CN110180096A - A kind of method of ultrashort wave adjuvant treatment children's herpangina - Google Patents

A kind of method of ultrashort wave adjuvant treatment children's herpangina Download PDF

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CN110180096A
CN110180096A CN201910445989.XA CN201910445989A CN110180096A CN 110180096 A CN110180096 A CN 110180096A CN 201910445989 A CN201910445989 A CN 201910445989A CN 110180096 A CN110180096 A CN 110180096A
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ultrashort wave
herpangina
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adjuvant treatment
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赵小苗
张刚
储海娟
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0625Mouth
    • A61M2210/065Throat; Pharynx
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0004Applications of ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0043Ultrasound therapy intra-cavitary

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Abstract

The invention discloses a kind of methods of ultrashort wave adjuvant treatment children's herpangina, comprising the following steps: S1 treatment object, S2 exclude screening, S3 drug therapy, S4 ultrashort wave therapy and S5 and observe and record the state of an illness.Increase lesion local drug concentration by the high frequency magnetic field of generation, enhances curative effect of medication.Vasopermeability can be enhanced simultaneously, promote local blood circulation, accelerate the dissipation of oedema and the excretion and elimination of metabolite, inflammatory products and bacteriotoxin, low dose of ultrashort wave can enhance monokaryon-mononuclear phagocyte system function, phagocyte quantity increases, phagocytic function enhancing, internal globulin, antibody, complement, agglutinin increase, alkaline phosphatase activities increase in peripheral blood leucocytes, LeIF potency increases, be conducive to the control and dissipation of inflammation, ultrashort wave can effectively inhibit the conduction of the patient feels nerve, thus reduction of patient feeling of pain.

Description

A kind of method of ultrashort wave adjuvant treatment children's herpangina
Technical field
The present invention relates to ultrasonic therapy children's herpangina technical field, specially a kind of ultrashort wave adjuvant treatment The method of children's herpangina.
Background technique
Herpangina is a kind of common Pediatric Acute infectious disease, there is disease incidence and infectious rate with higher, main To be caused by Coxsackie virus infection, clinical manifestation is pharyngeal pain, salivation, nausea, anorexia etc..Infant is because of pharyngeal blister when morbidity Rash and pain often can it is irritated, cry and scream, eating difficulties affect infant health, also bring great pain to household.Herpetic pharynx Gorge inflammation is self-limited disease (1-2 weeks), and active treatment can shorten the course of disease, prevent related complication.Herpangina is paediatrics More typical communicable disease, natural history is mostly at 1 week or so, and herpangina is using typical isthmus faucium portion as principal pathogenetic portion Position, it is the main positions of the infection of the upper respiratory tract caused by virus that peripheral lymphoid circulation is abundant.If nervous system is involved in infection, can be simultaneously It sends out encephalitis and neurogenic pulmonary edema serious, even results in nervous system dysfunction and multiple organ injury.It there is no spy at present Treatment method is imitated, mainly based on supportive treatment of suiting the medicine to the illness.Ultrashort wave is treated as a kind of physiotherapy factor, extensively in recent years Applied to the treatment of the diseases such as infantile pneumonia, rhinitis, parotitis, still, blister seldom but is applied to and without by ultrashort wave In the treatment of rash angina, for this purpose, providing a kind of method for being used to assist in the treatment of herpangina for ultrashort wave.
Summary of the invention
The purpose of the present invention is to provide a kind of methods of ultrashort wave adjuvant treatment children's herpangina, on solving State the problem of proposing in background technique.
To achieve the above object, the invention provides the following technical scheme: a kind of ultrashort wave assists in the treatment of the herpetic pharynx of children The method of gorge inflammation, it is characterised in that: the following steps are included:
S1: treatment object: 1. meet the diagnostic criteria [2] of herpangina in " Zhu Futang practical paidonosology " the 8th edition; 2. the age 1-7 years old;
S2: it excludes screening: in the treatment object of step S1, excluding the patient for having following any situation, 1. whole body Chronic disease, tumour and there is metallic foreign body etc. to have ultrashort wave therapy taboo person in vivo;2. infant C-RP is higher than 80mg/L or more Person;3. switching to hand-foot-and-mouth disease person in treatment;4. complication or adverse reactions people are mismatched or occur in midway treatment;
S3: drug therapy: routine medication is used;
S4: ultrashort wave therapy: after the drug therapy of step S3, patient's lesions position is controlled by ultrasonic instrument It treats, ultrasonic frequency is 30~300MHz, and wavelength is the electric current of 1~10m, one day 1~3 time, every time 6~8min, the course for the treatment of 3~5 It;
S5: it observes and records the state of an illness: 1. recording patient temperature and situation of bringing down a fever;2. observing mucous membrane of mouth and pharyngeal bleb subsiding Situation, and record regression time;3. observing adverse reaction.
Preferably, the conventional medicine is interferon nebulae inhalation.
Preferably, the ultrasonic instrument is low-power, and output power is 50~80W.
Preferably, the electrode to the distance between skin be 20~24mm.
Preferably, the frequency of the ultrasonic wave is 40.68MHz, wavelength 7.37m.
Preferably, the dosage of the ultrasonic therapy is low dose without heat.
Compared with prior art, the beneficial effects of the present invention are:
1, lesion local drug concentration is increased by the high frequency magnetic field of generation, enhances curative effect of medication.Blood vessel can be enhanced simultaneously Permeability, promote local blood circulation, accelerate the dissipation and metabolite of oedema, the excretion of inflammatory products and bacteriotoxin and It eliminates;
2, low dose of ultrashort wave can enhance monokaryon-mononuclear phagocyte system function, and phagocyte quantity increases, phagocytic function Enhancing, internal globulin, antibody, complement, agglutinin increase, and alkaline phosphatase activities increase in peripheral blood leucocytes, white thin Born of the same parents' interferon potency increases, and is conducive to the control and dissipation of inflammation;
3, ultrashort wave can effectively inhibit the conduction of the patient feels nerve, thus reduction of patient feeling of pain.
The rehabilitation course for thus accelerating patient alleviates the painful time of patient, and infant fitness is high, without bad anti- It answers, is worth clinically wideling popularize.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described, Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all Belong to the scope of protection of the invention.
Embodiment 1
A kind of method of ultrashort wave adjuvant treatment children's herpangina, comprising the following steps:
S1: treatment object: 1. meet the diagnostic criteria [2] of herpangina in " Zhu Futang practical paidonosology " the 8th edition; 2. the age 1-7 years old;
S2: it excludes screening: in the treatment object of step S1, excluding the patient for having following any situation, 1. whole body Chronic disease, tumour and there is metallic foreign body etc. to have ultrashort wave therapy taboo person in vivo;2. infant C-RP is higher than 80mg/L or more Person;3. switching to hand-foot-and-mouth disease person in treatment;4. complication or adverse reactions people are mismatched or occur in midway treatment;
S3: drug therapy: using routine medication, and conventional medicine is interferon nebulae inhalation;
S4: ultrashort wave therapy: after the drug therapy of step S3, patient's lesions position is controlled by ultrasonic instrument It treats, ultrasonic instrument is low-power, it is relatively common, such as the production of Shanghai Shanghai Medical Instrument High Technology Company, there are multiple systems Column may be implemented, output power 50W, ultrasonic frequency 30MHz, and the distance between electrode to skin is 20mm, and wavelength is The electric current of 1m, once a day, each 6min, the course for the treatment of 3 days, the dosage of ultrasonic therapy was low dose without heat;
S5: it observes and records the state of an illness: 1. recording patient temperature and situation of bringing down a fever;2. observing mucous membrane of mouth and pharyngeal bleb subsiding Situation, and record regression time;3. observing adverse reaction.
Embodiment 2
A kind of method of ultrashort wave adjuvant treatment children's herpangina: the following steps are included:
S1: treatment object: 1. meet the diagnostic criteria [2] of herpangina in " Zhu Futang practical paidonosology " the 8th edition; 2. the age 1-7 years old;
S2: it excludes screening: in the treatment object of step S1, excluding the patient for having following any situation, 1. whole body Chronic disease, tumour and there is metallic foreign body etc. to have ultrashort wave therapy taboo person in vivo;2. infant C-RP is higher than 80mg/L or more Person;3. switching to hand-foot-and-mouth disease person in treatment;4. complication or adverse reactions people are mismatched or occur in midway treatment;
S3: drug therapy: using routine medication, and conventional medicine is interferon nebulae inhalation;
S4: ultrashort wave therapy: after the drug therapy of step S3, patient's lesions position is controlled by ultrasonic instrument It treats, ultrasonic instrument is low-power, it is relatively common, such as the production of Shanghai Shanghai Medical Instrument High Technology Company, there are multiple systems Column may be implemented, output power 60W, and the distance between electrode to skin is 22mm, and the frequency of ultrasonic wave is 40.68MHz, Wavelength 7.37m, two times a day, each 7min, the course for the treatment of 4 days, the dosage of ultrasonic therapy was low dose without heat;
S5: it observes and records the state of an illness: 1. recording patient temperature and situation of bringing down a fever;2. observing mucous membrane of mouth and pharyngeal bleb subsiding Situation, and record regression time;3. observing adverse reaction.
Embodiment 3
A kind of method of ultrashort wave adjuvant treatment children's herpangina, comprising the following steps:
S1: treatment object: 1. meet the diagnostic criteria [2] of herpangina in " Zhu Futang practical paidonosology " the 8th edition; 2. the age 1-7 years old;
S2: it excludes screening: in the treatment object of step S1, excluding the patient for having following any situation, 1. whole body Chronic disease, tumour and there is metallic foreign body etc. to have ultrashort wave therapy taboo person in vivo;2. infant C-RP is higher than 80mg/L or more Person;3. switching to hand-foot-and-mouth disease person in treatment;4. complication or adverse reactions people are mismatched or occur in midway treatment;
S3: drug therapy: using routine medication, and conventional medicine is interferon nebulae inhalation;
S4: ultrashort wave therapy: after the drug therapy of step S3, patient's lesions position is controlled by ultrasonic instrument It treats, ultrasonic instrument is low-power, it is relatively common, such as the production of Shanghai Shanghai Medical Instrument High Technology Company, there are multiple systems Column may be implemented, output power 80W, ultrasonic frequency 300MHz, and the distance between electrode to skin is 24mm, and wavelength is The electric current of 10m, three times a day, each 8min, the course for the treatment of 5 days, the dosage of ultrasonic therapy was low dose without heat;
S5: it observes and records the state of an illness: 1. recording patient temperature and situation of bringing down a fever, 2. observes mucous membrane of mouth and pharyngeal bleb recession Situation, and record regression time, 3. observe adverse reaction.
It is compared by three groups of embodiments, 2 effect of embodiment is more preferable, becomes apparent from, that is to say, that power 60W, electrode to skin The distance between be 22mm, the frequency of ultrasonic wave is 40.68MHz, wavelength 7.37m, and two times a day, each 7min is imitated for the course for the treatment of 4 days Fruit is relatively good, also reflects, and has had reached within 4 days therapeutic effect, and the 5th day unobvious on the basis of taking a turn for the better.
Increase lesion local drug concentration by the high frequency magnetic field of generation, enhances curative effect of medication.It is logical that blood vessel can be enhanced simultaneously Permeability promotes local blood circulation, accelerates the dissipation and metabolite of oedema, the excretion of inflammatory products and bacteriotoxin and disappear It removes, low dose of ultrashort wave can enhance monokaryon-mononuclear phagocyte system function, and phagocyte quantity increases, and phagocytic function enhances this It is a China Rehabilitation theory and practice in June, 2018 volume 24 the 6th it is interim " ultrashort wave promotes macrophage phenotype conversion simultaneously Inhibit the effect of inflammatory reaction after Spinal Cord Injury in Rats " in just illustrate, during ultrashort wave therapy, phagocyte is from M1 to M2 Type transformation, it is well known that the killing ability of M2 is stronger, and effect is more preferable, so as to shorten the anginal course of disease;
Internal globulin, antibody, complement, agglutinin increase, and alkaline phosphatase activities increase in peripheral blood leucocytes, white Cell Interferon potency increases, and is conducive to the control and dissipation of inflammation;
Ultrashort wave can effectively inhibit the conduction of the patient feels nerve, thus reduction of patient feeling of pain.[Wen Xinyi, Cai Ai Precious ultrashort wave and pulsating field treat 423 observation of curative effect [J] China Rehabilitations of mumps, 1993,8 (2): 136- 137.]
Experimental comparison
1, personnel choose: choosing the herpetic pharynx that peace one attached institute, medical university, 2 months 2018~2 months 2019 Pediatric Clinics are seen and treated patients Gorge inflammation infant 112.According to medical sequence, it is randomly divided into control group 56 and experimental group 56.Control group male 26, female 30, put down The equal age (3.8 ± 0.9 one full year of life);Experimental group male 29, female 27, average age (3.9+1.0 one full year of life);Two groups of infants are at age, property Not aspect comparing difference is not statistically significant (P > 0.05), is comparable.
2, it is included in standard: 1. meeting the diagnostic criteria [2] of herpangina in " Zhu Futang practical paidonosology " the 8th edition; 2. the age 1-7 years old;3. the course of disease was less than 2 days;4. not receiving treatment before medical;5. parents of hospitalized children knows and is ready to cooperate this research, Sign informed consent form;
1. exclusion criteria whole body chronic disease, tumour and has metallic foreign body etc. to have ultrashort wave therapy taboo person in vivo;② Infant C-RP is higher than 80mg/L or more person;3. switching to hand-foot-and-mouth disease person in treatment;4. complication is mismatched or is occurred in midway treatment And adverse reactions people;
3, condition: control group is using conventional drug therapy, that is, interferon is atomized and relieving cough and reducing sputum drug therapy is same When use, treat 5 days, experimental group increases ultrashort wave therapy, power 60W, electrode to skin on the basis of routine medication The distance between be 22mm, the frequency of ultrasonic wave is 40.68MHz, wavelength 7.37m, and two times a day, each 8min the course for the treatment of 5 days, is treated Criterion is imitated according to the standard of curative effect evaluation [2] in " practical paidonosology ".It is divided into effective, effective and invalid: 1. effective: 3 days Interior temperature recovery is normal, and bleb disappears, and feed is good, and ulcer surface starts to heal;2. effectively: body temperature peak descending, fever in 3 days Interval time increases, and the symptoms were significantly improved for pharyngalgia, and feed improves, and bleb significantly reduces, and ulcer surface still has redness, and faces in 5 days Bed symptom, sign disappear;3. invalid: the state of an illness does not disappear without symptom, sign in improvement, or even exacerbation or 5 days in 3 days.Always Efficient=(effective+effectively) and/total number of cases × 100%, obvious effective rate=effective/total number of cases × 100%.Statistics is as follows:
1 patients ' recovery situation of table
2 two groups of infant curative effects of table compare
3 two groups of infant fever times of table, bleb regression time compare
Experimental group total effective rate (94.6%) is higher than control group (87.5%) after treatment, and effective number of cases is apparently higher than control Group, difference are statistically significant (p < 0.05);The fever time (2.2 ± 0.58) of experimental group be shorter than control group (2.72 ± 0.59), difference is statistically significant (p < 0.05);Experimental group infant bleb, which is moved back, disappears the time (2.62 ± 0.56) also below control (3.30 ± 0.71) of group, it is statistically significant (p < 0.05) compared to difference, do not occur in two groups of therapeutic process bad anti- It answers.It illustrates to be remarkably improved curative effect better than simple drug therapy using ultrashort wave adjuvant treatment children's herpangina, Accelerate fever time and bleb regression time, is worth clinical expansion.
Note: it may be noted that because children's vessel wall elasticity is poor, nervus vasculairs function is more adult to be easier to disorder, treatment time If too long, may locally there be bleeding, therefore the ultrashort wave therapy time also foreshortens to 8 minutes/time in this research.In addition, small Youngster's epiphysis, eye are sensitive to ultrashort wave, should not use large dosage of [physiatrics], ultrashort therapeutic dose is in this research It is low dose of.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (6)

1. a kind of method of ultrashort wave adjuvant treatment children's herpangina, it is characterised in that: the following steps are included:
S1: treatment object: 1. meet the diagnostic criteria [2] of herpangina in " Zhu Futang practical paidonosology " the 8th edition;2. year Age 1-7 years old;
S2: it excludes screening: in the treatment object of step S1, excluding the patient for having following any situation, 1. whole body is chronic Disease, tumour and there is metallic foreign body etc. to have ultrashort wave therapy taboo person in vivo;2. infant C-RP is higher than 80mg/L or more person;③ Switch to hand-foot-and-mouth disease person in treatment;4. complication or adverse reactions people are mismatched or occur in midway treatment;
S3: drug therapy: routine medication is used;
S4: ultrashort wave therapy: after the drug therapy of step S3, treating patient's lesions position by ultrasonic instrument, Ultrasonic frequency is 30~300MHz, and wavelength is the electric current of 1~10m, one day 1~3 time, every time 6~8min, the course for the treatment of 3~5 days;
S5: it observes and records the state of an illness: 1. recording patient temperature and situation of bringing down a fever;2. observing mucous membrane of mouth and pharyngeal bleb recession feelings Condition, and record regression time;3. observing adverse reaction.
2. a kind of method of ultrashort wave adjuvant treatment children's herpangina according to claim 1, it is characterised in that: The conventional medicine is interferon nebulae inhalation.
3. a kind of method of ultrashort wave adjuvant treatment children's herpangina according to claim 1, it is characterised in that: The ultrasonic instrument is low-power, and output power is 50~80W.
4. a kind of method of ultrashort wave adjuvant treatment children's herpangina according to claim 3, it is characterised in that: The electrode to the distance between skin be 20~24mm.
5. a kind of method of ultrashort wave adjuvant treatment children's herpangina according to claim 3, it is characterised in that: The frequency of the ultrasonic wave is 40.68MHz, wavelength 7.37m.
6. a kind of method of ultrashort wave adjuvant treatment children's herpangina according to claim 1, it is characterised in that: The dosage of the ultrasonic therapy is low dose without heat.
CN201910445989.XA 2019-05-27 2019-05-27 A kind of method of ultrashort wave adjuvant treatment children's herpangina Pending CN110180096A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2198704C1 (en) * 2001-10-16 2003-02-20 Научно-клинический центр оториноларингологии Method for treating the cases of pharyngitis
CN1795947A (en) * 2004-12-24 2006-07-05 重庆融海超声医学工程研究中心有限公司 Ultrasonic therapy gun
CN101085397A (en) * 2006-06-07 2007-12-12 重庆海扶(Hifu)技术有限公司 Optical sight glass orthoptic ultrasonic therapy system
CN104324450A (en) * 2014-04-11 2015-02-04 秦皇岛嘎哈医疗电子仪器有限公司 Ultra-optical-frequency pulverization treatment instrument

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2198704C1 (en) * 2001-10-16 2003-02-20 Научно-клинический центр оториноларингологии Method for treating the cases of pharyngitis
CN1795947A (en) * 2004-12-24 2006-07-05 重庆融海超声医学工程研究中心有限公司 Ultrasonic therapy gun
CN101085397A (en) * 2006-06-07 2007-12-12 重庆海扶(Hifu)技术有限公司 Optical sight glass orthoptic ultrasonic therapy system
CN104324450A (en) * 2014-04-11 2015-02-04 秦皇岛嘎哈医疗电子仪器有限公司 Ultra-optical-frequency pulverization treatment instrument

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