CN104257954A - Traditional Chinese medicine preparation for treating epilepsy - Google Patents
Traditional Chinese medicine preparation for treating epilepsy Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating epilepsy. The selected raw materials of the preparation are as follows in parts by weight: 20-30 g of rhizoma acori Talarinowii, 10-20 g of Saruma henryi, 10-20 g of uncaria, 10-20 g of Semen Pharbitidis, 10-20 g of Valerian root, 8-15 g of centipedes, 8-15 g of scorpion, 8-15 g of stiff silkworm, 8-15 g of lumbricus, 8-12 g of periostracum cicada, 8-12 g of cornu saigae tataricae and 8-12 g of calculus bovis. The compatibility of the preparation is accurate; reinforcement and elimination in combination are realized; both symptoms and root causes can be treated; diagnosis and treatment based on an overall analysis of the illness and the patient's condition are brought into full play; the traditional Chinese medicine preparation is used for treating epilepsy, has the efficacies of inducing resuscitation and sweeping phlegm, calming liver wind, clearing heat, sedating, activating meridian and detoxifying and is worthwhile being promoted and applied.
Description
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating epilepsy.
Background technology
Epilepsy is commonly called as epilepsy, is the electric discharge of cerebral neuron paroxysmal abnormality, causes a kind of chronic disease of of short duration cerebral disorder.Show as and break out, automatically stop, the obstacle of recurrent sensation of movement, spirit and consciousness aspect.Modern medicine thinks that the reason that epilepsy occurs can be divided into two classes: constitutional (functional) epilepsy and Secondary cases (symptomatic) epilepsy.General tonic-clonic seizure (grand mal), petit mal (petit mal), simple partial seizure, complex partial seizures (psychomotor attack), autonomic seizures (diencephalon) can be divided into again according to its clinical manifestation type.
Epilepsy is divided into different periods, and treatment has the possibility cancerated not in time, adds uncertain danger, therefore answer active treatment to patient.Current doctor trained in Western medicine mainly adopts medicine and operative treatment, but the drug administration cycle is long, side effect is large, patient is therefore very painful, for removing the misery of the mind & body of patient, according to the principle of tcm syndrome differentiation and treatment, treating both the principal and the secondary aspects of a disease at the same time, we provide a kind of Chinese medicine preparation, be used for the treatment of epilepsy and achieve good effect.
Summary of the invention
Instant invention overcomes the technical deficiency existed in treatment epilepsy at present, provide that a kind of side effect is little, evident in efficacy, cheap, patient compliance is higher, cure after the Chinese medicine preparation for the treatment of epilepsy that not easily recurs.
The technical solution adopted in the present invention is:
Treat a Chinese medicine preparation for epilepsy, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Acori Graminei 20-30 gram, Herba Asari 10-20 gram, Ramulus Uncariae Cum Uncis 10-20 gram, Semen Pharbitidis 10-20 gram, Rhizoma et radix valerianae 10-20 gram, Scolopendra 8-15 gram, Scorpio 8-15 gram, Bombyx Batryticatus 8-15 gram, Pheretima 8-15 gram, Periostracum Cicadae 8-12 gram, Cornu Saigae Tataricae 8-12 gram, Calculus Bovis 8-12 gram.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Acori Graminei 20 grams, Herba Asari 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Semen Pharbitidis 10 grams, Rhizoma et radix valerianae 10 grams, Scolopendra 8 grams, Scorpio 8 grams, Bombyx Batryticatus 8 grams, Pheretima 8 grams, Periostracum Cicadae 8 grams, Cornu Saigae Tataricae 8 grams, Calculus Bovis 8 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Acori Graminei 25 grams, Herba Asari 15 grams, Ramulus Uncariae Cum Uncis 15 grams, Semen Pharbitidis 15 grams, Rhizoma et radix valerianae 15 grams, Scolopendra 12 grams, Scorpio 12 grams, Bombyx Batryticatus 12 grams, Pheretima 12 grams, Periostracum Cicadae 10 grams, Cornu Saigae Tataricae 10 grams, Calculus Bovis 10 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Acori Graminei 30 grams, Herba Asari 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Semen Pharbitidis 20 grams, Rhizoma et radix valerianae 20 grams, Scolopendra 15 grams, Scorpio 15 grams, Bombyx Batryticatus 15 grams, Pheretima 15 grams, Periostracum Cicadae 12 grams, Cornu Saigae Tataricae 12 grams, Calculus Bovis 12 grams.
The instructions of taking of Chinese medicine preparation of the present invention is: after being mixed by the raw material Chinese medicine of above-mentioned weight proportion, 1 dose/day, every agent head decocts the 500ml that adds water, and warm fire boils 25 minutes, extracting juice 250ml; Two decoct the 300ml that adds water, and warm fire boils 20 minutes, extracting juice 150ml.Two decoct mixing, sooner or later empty stomach decoction being taken hot.20 doses was 1 course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Rhizoma Acori Graminei: acrid in the mouth, hardship, warm in nature; GUIXIN, stomach warp.There is removing dampness appetizing, eliminating phlegm of having one's ideas straightened out, effect of refreshment Fructus Alpiniae Oxyphyllae.
Herba Asari: taste is micro-pungent, bitter, sweet, light, gas is fragrant, and property is put down; Return liver, kidney, small intestinal, urinary bladder channel.There is inducing diuresis for treating stranguria syndrome, heat clearing away is relieving convulsion, expelling summer-heat, XIAOFENG SAN gas, go effect of amassing, invigorating blood circulation.
Ramulus Uncariae Cum Uncis: sweet in the mouth, micro-hardship, cold nature; Return liver, pericardium channel.There is suppressing the hyperactive liver to relieve the wind syndrome, effect that heat clearing away is relieving convulsion.
Semen Pharbitidis: bitter in the mouth, cold in nature; Return lung, kidney, large intestine channel.Have removing water retention by purgation relieving constipation, drink is washed in expectorant, and parasite killing attacks long-pending effect.
Rhizoma et radix valerianae: acrid in the mouth, micro-sweet, warm in nature; GUIXIN, liver two warp.There is calmness of calming the nerves, wind dispelling spasmolytic, promoting regeneration of the tissue and arresting bleeding, effect of pain relieving.
Scolopendra: salty in the mouth, warm in nature; Return Liver Channel.There is effect of relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.
Scorpio: acrid in the mouth, slightly warm in nature; Return Liver Channel.There is effect of relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain, detoxicating and resolving stagnation of pathogens.
Bombyx Batryticatus: salty in the mouth, pungent, property is put down; Return liver, lung meridian.There is effect of relieving spasm by subduing liver-wind, expelling wind and clearing away heat, dissipating phlegm and resolving masses.
Pheretima: salty in the mouth, cold in nature; Return liver, spleen, urinary bladder channel.There is calming wind and dredging collateral, heat clearing away be relieving convulsion, relieving asthma, effect of diuresis.
Periostracum Cicadae: sweet in the mouth, cold in nature; Return liver, lung meridian.There is dispelling wind and heat pathogens, removing heat in the liver to subdue the wind syndrome, effect of relieving convulsion.
Cornu Saigae Tataricae: salty in the mouth, cold in nature; Return liver, heart channel.There is suppressing the hyperactive liver to relieve the wind syndrome, heat clearing away be relieving convulsion, effect of removing toxic substances.
Calculus Bovis: bitter in the mouth, cool in nature; Return liver, heart channel.There is effect of the spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., waking up the patient from unconsciousness by dissipating phlegm, heat-clearing and toxic substances removing.
Epilepsy belongs to the traditional Chinese medical science " phlegm syndrome " category, and its Etiological mostly is that key is clearly disturbed, unit's out of control, refreshing machine of god is at random, brain is not filled, the weary machine of brain god, causes dusk to be fallen forward twitching, in a trance uneasy, One's eyesight is restrained etc.Modern medicine thinks that the generation of primary disease is lost with after multiple brain disease damage, dysbolismus, hyperpyrexia convulsion, wound, infection, poisoning, intracranial tumor, cerebrovascular disease, Nutrition and Metabolism disease etc. are relevant, wherein, heart storing spirit, the main marrow of kidney storing essence, burnt in spleen fortune, liver controlling conveyance and dispersion and harmonizing the functional activities of vital QI, visible brain and the heart, all dirty functions of liver,kidney,spleen are relevant, therefore treat primary disease to show according to patient's different symptoms, with eliminating phlegm of having one's ideas straightened out, tranquillizing and allaying excitement, fundamentally adjust body, dialectical treatment, applies in a flexible way, and Fang Xianqi is imitated.
In Chinese medicine preparation of the present invention, Rhizoma Acori Graminei can be had one's ideas straightened out eliminating phlegm, refreshment Fructus Alpiniae Oxyphyllae; Herba Asari, Ramulus Uncariae Cum Uncis, Semen Pharbitidis can removing water retention by purgation relieving constipations, and heat clearing away is calm; Rhizoma et radix valerianae, Scolopendra, Scorpio, Bombyx Batryticatus can relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain, eliminating stagnation; Pheretima, Periostracum Cicadae can dispelling wind and heat pathogens, calm relieving convulsion; Cornu Saigae Tataricae, Calculus Bovis can suppressing the hyperactive liver to relieve the wind syndrome, heat-clearing and toxic substances removing.Full side's compatibility is superior, attacks benefit and executes mutually, treating both the principal and secondary aspects of a disease, has given full play to the advantage that differential diagnosis in tcm treats, has been used for the treatment of epilepsy, has eliminating phlegm of having one's ideas straightened out, suppressing the hyperactive liver to relieve the wind syndrome, and heat clearing away is calm, dredging collateral, the merit of removing toxic substances, clinic promotion and application.
For investigating clinical efficacy and the safety of medicine of the present invention further, we select the routine out-patient of certain hospital 66 to carry out clinical trial; Minimum 38 years old of age, maximum 81 years old, average 59 years old; The course of disease is the shortest 3 months, the longest 3 years, average 2 years; Generalized tonic-clonic patient 8 example, petit mal patient 14 example, simple partial seizure patient 13 example, complex partial seizures patient 13 example, autonomic seizures patient 18 example.
Criterion of therapeutical effect:
Cure: clinical symptoms, sign disappear, and do not reaccess.
Effective: clinical symptoms, sign obviously alleviate, and seizure frequency significantly reduces.
Effective: clinical symptoms, sign slightly alleviated, and seizure frequency decreases.
Invalid: clinical symptoms, sign all remain unchanged, do not improve completely.
Therapeutic Method:
After being mixed by the raw material Chinese medicine of above-mentioned weight proportion, add water fried, every agent head decocts the 500ml that adds water, and warm fire boils 25 minutes, extracting juice 250ml; Two decoct the 300ml that adds water, and warm fire boils 20 minutes, extracting juice 150ml.Two decoct mixing, every day 1 dose, point morning and evening 2 decoction being taken hot.20 doses was 1 course for the treatment of.
Efficacy result:
1. clinical efficacy result:
After treatment, cure 31 examples, effective 17 examples, effective 12 examples, invalid 6 examples; Cure rate 47.0%, obvious effective rate 25.8%, effective percentage 18.2%, inefficiency 9.1%, total effective rate 91.0%.Detailed results is in table 1.
| Number of cases | Cure n (%) | Effective n (%) | Effective n (%) | Invalid n (%) | Effective percentage n (%) |
| 66 | 31(47.0) | 17(25.8) | 12(18.2) | 6(9.1) | 60(91.0) |
Table 1: clinical efficacy result table after treatment
2. classifying type disease efficacy result:
After treatment, statistics finds, generalized tonic-clonic outbreak treated effect is 75.0%, petit mal treated effect is 92.9%, simple partial seizure treated effect is 92.3%, complex partial seizures treated effect is 92.3%, autonomic seizures treated effect is 94.4%, can treat in adenofibroma of breast by Chinese medicine preparation of the present invention, curative effect is autonomic seizures > petit mal > simple partial seizure=complex partial seizures > generalized tonic-clonic outbreak.Detailed results is in table 2.
Table 2: classifying type disease efficacy result synopsis
| Disease title | Number of cases n | Cure n | Effective n | Effective n | Invalid n | Effective percentage (%) |
| Generalized tonic-clonic shows effect | 8 | 3 | 2 | 1 | 2 | 75.0 |
| Petit mal | 14 | 7 | 3 | 3 | 1 | 92.9 |
| Simple partial seizure | 13 | 7 | 2 | 3 | 1 | 92.3 |
| Complex partial seizures | 13 | 4 | 5 | 1 | 1 | 92.3 |
| Autonomic seizures | 18 | 10 | 5 | 4 | 1 | 94.4 |
3. side effect reaction
In the treatment, all there is not obvious adverse reaction in all patients.
Result shows, Chinese medicine preparation of the present invention, by Chinese medicine differential diagnosis of diseases and the dialectical principle combined, is attacked and mended double making, treating both the principal and the secondary aspects of a disease at the same time, is used for the treatment of that epilepsy is evident in efficacy, cure rate is high and not easily recurs, avoiding surgical injury simultaneously, there is certain advantage, clinic promotion and application.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of epilepsy, chooses Rhizoma Acori Graminei 20 grams, Herba Asari 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Semen Pharbitidis 10 grams, Rhizoma et radix valerianae 10 grams, Scolopendra 8 grams, Scorpio 8 grams, Bombyx Batryticatus 8 grams, Pheretima 8 grams, Periostracum Cicadae 8 grams, Cornu Saigae Tataricae 8 grams, Calculus Bovis 8 grams.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of epilepsy, Rhizoma Acori Graminei 25 grams, Herba Asari 15 grams, Ramulus Uncariae Cum Uncis 15 grams, Semen Pharbitidis 15 grams, Rhizoma et radix valerianae 15 grams, Scolopendra 12 grams, Scorpio 12 grams, Bombyx Batryticatus 12 grams, Pheretima 12 grams, Periostracum Cicadae 10 grams, Cornu Saigae Tataricae 10 grams, Calculus Bovis 10 grams.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of epilepsy, Rhizoma Acori Graminei 30 grams, Herba Asari 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Semen Pharbitidis 20 grams, Rhizoma et radix valerianae 20 grams, Scolopendra 15 grams, Scorpio 15 grams, Bombyx Batryticatus 15 grams, Pheretima 15 grams, Periostracum Cicadae 12 grams, Cornu Saigae Tataricae 12 grams, Calculus Bovis 12 grams.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is verified further:
Case 1
Liu so-and-so, male 58 years old.Just there is slight epilepsy syndromes before half a year in patient, recently occurs sudden loss of consciousness, then first tetanic rear clonic spasm, and companion screams, purplish complexion, urinary incontinence, tongue bite, spit out white foams or blood foam, platycoria symptom.Be diagnosed as through examination in hospital: generalized tonic-clonic outbreak type epilepsy.Take Chinese medicine preparation of the present invention upon somebody's introduction to treat, take medicine 20 doses, without uncomfortable, symptom alleviates.Serve on 3 months, substantially fully recover.Follow up a case by regular visits to 2 years without recurrence.
Case 2
Huang, male 41 years old.Patient repeatedly occurs that sudden ergasia is interrupted over nearly 1 year, loss of consciousness symptom.Show through examination in hospital: symptom is once shown effect second more than the several seconds to ten, and electroencephalogram occurs that 3 times/second slow or sharp slow waves of sour jujube are comprehensive.Be diagnosed as: outbreak type of losing virginity epilepsy.Take Chinese medicine preparation of the present invention to this hospital to treat, take medicine 20 doses, symptom alleviates.Serve on 2 months, substantially fully recover.Follow up a case by regular visits to 2 years without recurrence.
Case 3
Zhu, male 46 years old.Closely repeatedly there is disturbance of consciousness in various degree and significantly thinking, consciousness, emotion and Psychomotor disorders over the past half year in patient, with the automatism such as fugue, sleep-walking.Be diagnosed as through examination in hospital: complex partial seizures type epilepsy.Take Chinese medicine preparation of the present invention to this hospital to treat, take medicine 20 doses, symptom alleviates.Serve on 3 months, substantially fully recover.Follow up a case by regular visits to 2 years without recurrence.
Claims (4)
1. treat a Chinese medicine preparation for epilepsy, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Acori Graminei 20-30 gram, Herba Asari 10-20 gram, Ramulus Uncariae Cum Uncis 10-20 gram, Semen Pharbitidis 10-20 gram, Rhizoma et radix valerianae 10-20 gram, Scolopendra 8-15 gram, Scorpio 8-15 gram, Bombyx Batryticatus 8-15 gram, Pheretima 8-15 gram, Periostracum Cicadae 8-12 gram, Cornu Saigae Tataricae 8-12 gram, Calculus Bovis 8-12 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Acori Graminei 20 grams, Herba Asari 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Semen Pharbitidis 10 grams, Rhizoma et radix valerianae 10 grams, Scolopendra 8 grams, Scorpio 8 grams, Bombyx Batryticatus 8 grams, Pheretima 8 grams, Periostracum Cicadae 8 grams, Cornu Saigae Tataricae 8 grams, Calculus Bovis 8 grams.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Acori Graminei 25 grams, Herba Asari 15 grams, Ramulus Uncariae Cum Uncis 15 grams, Semen Pharbitidis 15 grams, Rhizoma et radix valerianae 15 grams, Scolopendra 12 grams, Scorpio 12 grams, Bombyx Batryticatus 12 grams, Pheretima 12 grams, Periostracum Cicadae 10 grams, Cornu Saigae Tataricae 10 grams, Calculus Bovis 10 grams.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Acori Graminei 30 grams, Herba Asari 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Semen Pharbitidis 20 grams, Rhizoma et radix valerianae 20 grams, Scolopendra 15 grams, Scorpio 15 grams, Bombyx Batryticatus 15 grams, Pheretima 15 grams, Periostracum Cicadae 12 grams, Cornu Saigae Tataricae 12 grams, Calculus Bovis 12 grams.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105194228A (en) * | 2015-11-12 | 2015-12-30 | 贵州盛世保康茶开发有限公司 | Miao medicine for treating epilepsy |
| CN105816653A (en) * | 2016-04-30 | 2016-08-03 | 何佑兵 | Traditional Chinese medicine composition for treating epilepsy and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1177498A (en) * | 1997-08-27 | 1998-04-01 | 黄朝明 | Chinese traditional medicine for treating epilepsy |
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| CN1177498A (en) * | 1997-08-27 | 1998-04-01 | 黄朝明 | Chinese traditional medicine for treating epilepsy |
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| Title |
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| 南征等主编: "《任继学用药心得十讲》", 31 January 2014, 中国医药科技出版社 * |
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| CN105194228A (en) * | 2015-11-12 | 2015-12-30 | 贵州盛世保康茶开发有限公司 | Miao medicine for treating epilepsy |
| CN105816653A (en) * | 2016-04-30 | 2016-08-03 | 何佑兵 | Traditional Chinese medicine composition for treating epilepsy and preparation method thereof |
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