CN110141640A - A kind of anti-bacterial, anti-itching Chinese medicine composition and its application - Google Patents

A kind of anti-bacterial, anti-itching Chinese medicine composition and its application Download PDF

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CN110141640A
CN110141640A CN201910520622.XA CN201910520622A CN110141640A CN 110141640 A CN110141640 A CN 110141640A CN 201910520622 A CN201910520622 A CN 201910520622A CN 110141640 A CN110141640 A CN 110141640A
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extract
parts
essential oil
oil
chinese medicine
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杨子雄
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Fujian Hailewei Bio Engineering Co Ltd
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Fujian Hailewei Bio Engineering Co Ltd
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Abstract

The present invention relates to field of Chinese medicinal composition, provide a kind of anti-bacterial, anti-itching Chinese medicine composition, by weight percentage, the raw material of the composition includes at least, 1-3% Gotu Kola P.E, 5-10% purslane extract, 3-6% camomile extract, 2-5% hamamelis extract, 3-10% Flos Lonicerae extractive solution, 1-3% Roselle flower extract, 5-10% haw thorn extract, 3-10% mint extract, 5-10% aloe extract, 1-5% glycine betaine, solvent supply surplus;Additionally provide ointment, lotion, antipruritic water comprising Chinese medicine composition.

Description

A kind of anti-bacterial, anti-itching Chinese medicine composition and its application
Technical field
The present invention relates to field of Chinese medicinal composition, specifically, further relating to a kind of anti-bacterial, anti-itching Chinese medicine composition and its application.
Background technique
Itch is a kind of offending feeling of skin and mucosa for causing to scratch desire.The reason of causing pruitus is very Complexity, such as bite by mosquitos, sarcoptic mite parasitism skin, drug allergy, dermatitis, eczema, fungal infection etc., can lead to skin scabies Itch.Under pathological conditions, keratinocyte can be with secrete cytokines, amine, neuropeptide, nerve growth factor, opioids Substance of itching is caused with a variety of endogenous such as eicosanoid, stimulates histamine release of mast cell or direct sensitization skin C- nerve fibre sense Receiver induces pruitus.External treatment with Chinese medicine itch multiselect moisturizes work with dispelling wind and eliminating dampness, removing toxic substances desinsection, nourshing blood and promoting blood circulation, cool blood Drug, it is most common have kuh-seng, Cortex Phellodendri, the fruit of summer cypress, frutus cnidii, cortex dictamni, Chinese prickly ash, the achene of Siberian cocklebur, radix saposhnikoviae, cicada slough, Radix Angelicae Sinensis, Peppermint.The antipruritic product based on Western medicine, for example, antihistamine diphenhydramine, chlorpheniramine (chlorphenamine maleate), cyproheptadine, Ketotifen, Loratadine;Corticoid medicine momestasone furoate etc..In addition also some Chinese patent drug such as Skin bacterial flora, "Runzao Zhiyang Capsule", Shiduqing Capsule, Pifubing Xuedu Pill etc..Children are the important crowds with cutaneous pruritus, but youngster Virgin constitution be not it is strong as adult, existing Anti-itch Products can skin etc. to this specific group for children Certain irritation is generated, is unfavorable for children's use, so needing to develop one kind can be with high security and mildly antipruritic The product of excellent effect.
Summary of the invention
In order to solve the above technical problems, the first aspect of the invention provides a kind of anti-bacterial, anti-itching Chinese traditional medicine composition Object, by weight percentage, raw material include at least, 1-3% Gotu Kola P.E, 5-10% purslane extract, and the ocean 3-6% is sweet Chrysanthemum extract, 2-5% hamamelis extract, 3-10% Flos Lonicerae extractive solution, 1-3% Roselle flower extract, 5-10% hawthorn Extract, 3-10% mint extract, 5-10% aloe extract, 1-5% glycine betaine, solvent supply surplus.
As a kind of perferred technical scheme, heretofore described composition, by weight percentage, raw material at least wraps Contain, 1.5-2.5% Gotu Kola P.E, 6-9% purslane extract, 3.5-5.5% camomile extract, 1.5-2% gold thread Prunus mume extract, 2-4% Flos Lonicerae extractive solution, 1.5-2.5% Roselle flower extract, 6-9% haw thorn extract, 5-7% peppermint Extract, 2-4% glycine betaine, solvent supply surplus.
As a kind of perferred technical scheme, the raw material of heretofore described composition also includes Fructus Monordicae extract, Pu Public English extract;The haw thorn extract, Fructus Monordicae extract, dandelion extract weight ratio are 1:(0.1-1): (0.5-1).
As a kind of perferred technical scheme, it is 1-10% that the raw material of heretofore described composition, which also includes weight ratio, Plants essential oil;The plants essential oil is selected from citronella oil, spearmint oil, curcuma oil, Lavender, Geranium Essential, folium artemisiae argyi essence Oil, eucalyptus citriodora essential oil, clove oil, camellia seed essential oil, Catnip essential oil, thyme essential oil, Rosemary Oil, castor oil, wood Jiang Zi essential oil, Lavender, Asian puccoon essential oil, fragrant Fructus Perillae quintessence oil, spearmint essential oil, pot marigold essential oil, deodar essential oil, juniperko Essential oil, motherwort essential oil, Cortex Eucommiae essential oil, refined jasmine oil, Rosa Damascana, osmanthus essential oil, lemon grass (Cymbopogon citratus) essential oil, tea oil, grape fruit One of essential oil or a variety of combinations.
As a kind of perferred technical scheme, heretofore described solvent is water and/or small molecular alcohol.
As a kind of perferred technical scheme, the raw material of heretofore described composition also includes phytosterol, grape pip Extract;The phytosterol, grape seed extract, mint extract weight ratio be 1:(0.1-0.5): (0.5-1).
As a kind of perferred technical scheme, heretofore described plants essential oil is citronella oil, Lavender, fish pelargonium Essential oil, P-Cymene, Rosemary Oil, grapefruit essential oil composition;The citronella oil, Lavender, Geranium Essential, P-Cymene, Rosemary Oil, grapefruit essential oil weight ratio be 1:(0.1-1): (0.1-0.5): (0.5-1): (0.5-1): (0.1-0.5)。
The second aspect of the invention provides a kind of lotion comprising the Chinese medicine composition, by weight, raw material It includes at least, 30-50 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 0.1-0.5 parts of thickeners, 1-5 parts of stearic acid, 30-50 parts Glycerol, 20-40 parts of deionized waters, 5-10 parts of surfactants.
The third aspect of the invention provides a kind of lotion comprising the Chinese medicine composition, by weight, raw material It includes at least, 30-50 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 0.1-0.5 parts of thickeners, 1-5 parts of stearic acid, 30-50 parts Glycerol, 20-40 parts of deionized waters, 5-10 parts of surfactants.
The fourth aspect of the invention provides a kind of antipruritic water comprising the Chinese medicine composition, by weight, former Material includes at least, and 20-30 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 1-5 parts of stearic acid, 20-40 parts of glycerol, 40-60 parts are gone Ionized water, 5-10 parts of surfactants.
With reference to following details, it is easier to understand technical characteristic, content and advantage described in previous section in the present invention.
Specific embodiment
Unless otherwise indicated, from context cues or belong to the convention of the prior art, otherwise number all in the application It is all based on weight with percentage, and test and characterizing method used is all synchronous with the submission date of the application.If existing There is defining for the concrete term disclosed in technology inconsistent with any definition provided herein, then with provided herein Subject to term definition.
It is further clear, complete that the technical characteristic work in technical solution is provided to the present invention With reference to embodiment Description, not to the limitation of its protection scope.
Word " preferred ", " preferably ", " preferred " in the present invention etc. refer to, can provide certain in some cases The embodiment of the present invention of a little beneficial effects.However, other embodiments may also under identical circumstances or in the case of other It is preferred.In addition, not implying that other embodiments are unavailable to the statement of one or more preferred embodiments, it is not yet It is intended to exclude other embodiments except the scope of the present invention.The source of unmentioned component is commercially available in the present invention.
The first aspect of the invention provides a kind of anti-bacterial, anti-itching Chinese medicine composition, and by weight percentage, raw material is extremely It less include 1-3% Gotu Kola P.E, 5-10% purslane extract, 3-6% camomile extract, the extraction of 2-5% witch hazel Object, 3-10% Flos Lonicerae extractive solution, 1-3% Roselle flower extract, 5-10% haw thorn extract, 3-10% mint extract, 5-10% aloe extract, 1-5% glycine betaine, solvent supply surplus.
In some preferred embodiments, by weight percentage, the raw material of the composition includes at least, 1.5- 2.5% Gotu Kola P.E, 6-9% purslane extract, 3.5-5.5% camomile extract, 2.5-3.5% witch hazel are extracted Object, 5-8% Flos Lonicerae extractive solution, 1.5-2.5% Roselle flower extract, 6-9% haw thorn extract, 5-7% mint extract, 6-8% aloe extract, 2-4% glycine betaine, solvent supply surplus.
In some preferred embodiments, by weight percentage, the raw material of the composition is included at least, and 2% Gotu Kola P.E, 8% purslane extract, 4.5% camomile extract, 1.8% hamamelis extract, 3% honeysuckle mention Take liquid, 2% Roselle flower extract, 8% haw thorn extract, 6% mint extract, 7% aloe extract, 3% glycine betaine is molten Surplus is supplied in agent.
No. CAS of the Gotu Kola P.E is 84696-21-9;No. CAS of the purslane extract is 90083- 07-1;No. CAS of the camomile extract is 8015-92-7;No. CAS of the hamamelis extract is 84696-19-5; No. CAS of the Flos Lonicerae extractive solution is 84603-62-3;The Roselle flower extract EINECS is 923-971-0;Institute No. CAS of haw thorn extract is stated as 64820-99-1;No. CAS of the mint extract is 90063-97-1;The aloe mentions No. CAS for taking object is 8001-97-6;No. CAS of the glycine betaine is 107-43-7.
In some embodiments, the raw material of the composition also includes Fructus Monordicae extract, dandelion extract;It is described Haw thorn extract, Fructus Monordicae extract, dandelion extract weight ratio are 1:(0.1-1): (0.5-1);Preferably, the hawthorn Extract, Fructus Monordicae extract, dandelion extract weight ratio are 1:(0.3-0.7): (0.6-0.9);It is furthermore preferred that the mountain Short, bristly hair or beard extract, Fructus Monordicae extract, dandelion extract weight ratio are 1:0.5:0.8.
The present invention provides a kind of anti-bacterial, anti-itching Chinese medicine compositions, wherein being comprising a variety of natural plant active components A kind of pure plant preparation, can effective bactericidal, also have the effects that antipruritic, anti-inflammatory;In the present invention, it was discovered that especially Be used in compounding using haw thorn extract, Fructus Monordicae extract, dandelion extract three can play excellent synergy can So that lasting medicine is stablized, thus it is speculated that possible cause is amino acid, vitamin and mineral rich in Fructus Monordicae extract Matter has good permeability to skin, and more minerals can be improved skin and be extracted to hawthorn with active cell in Siraitia grosvenorii The osmotic absorption of the ingredient of procyanidine, flavonoids and triterpenes in object acts on, and Siraitia grosvenorii mineral and hawthorn mention Take the microelement in object can promote and improve minerals dandelion extract to various bacteriums have it is stronger killing and Inhibiting effect and the metabolism and immunity for improving Skin Cell.
In some embodiments, the raw material of the composition also includes phytosterol, grape seed extract;The plant Sterol, grape seed extract, mint extract weight ratio be 1:(0.1-0.5): (0.5-1);Preferably, the plant steroid Alcohol, grape seed extract, mint extract weight ratio be 1:(0.2-0.4): (0.6-0.9);It is furthermore preferred that the plant steroid Alcohol, grape seed extract, mint extract weight ratio be 1:0.3:0.75.
In the Chinese medicine composition provided by the invention with anti-bacterial, anti-itching effect, have property mild, it is without side-effects, be suitable for Children use, and discovery is used in conjunction with using phytosterol, grape seed extract, mint extract in the present invention, reduce thin Volatilizable oil volatility, can make composition more mild in lotus extract,;Speculating possible cause is, phytosterol tool There is natural lipid property, have the effect of having with Skin Cell compatible well, can reduce the surface layer tension of skin, promote skin Skin surface layer in the procyanidine and mint extract in grape seed extract it is effective at absorption.And procyanidine is absorbed It can be very good maintenance Skin Cell later, further enhance the infiltration to the natural activity component in plants essential oil, make product Anti-bacterial, anti-itching effect greatly promoted.
No. CAS of the Fructus Monordicae extract is 88901-36-4;No. CAS of the dandelion extract is 68990- 74-9;No. CAS of the phytosterol is 85681-87-4;No. CAS of the grape seed extract is 84929-27-1.
In some embodiments, the raw material of the composition also includes the plants essential oil that weight ratio is 1-10%;It is preferred that , the raw material of the composition also includes the plants essential oil that weight ratio is 3-7%;It is furthermore preferred that the raw material of the composition is also The plants essential oil for being 5% comprising weight ratio.
In some embodiments, the plants essential oil is selected from citronella oil, spearmint oil, curcuma oil, Lavender, day Zhu Kui essential oil, P-Cymene, eucalyptus citriodora essential oil, clove oil, camellia seed essential oil, Catnip essential oil, thyme essential oil, rosemary Essential oil, castor oil, Litsea pungens essential oil, Lavender, Asian puccoon essential oil, fragrant Fructus Perillae quintessence oil, spearmint essential oil, pot marigold essential oil, Deodar essential oil, juniper berry essential oil, motherwort essential oil, Cortex Eucommiae essential oil, refined jasmine oil, Rosa Damascana, osmanthus essential oil, lemon grass (Cymbopogon citratus) essence Oil, tea oil, one of grapefruit essential oil or a variety of combinations;Preferably, the plants essential oil is selected from citronella oil, lavender One of essential oil, Geranium Essential, P-Cymene, Rosemary Oil, grapefruit essential oil, thyme essential oil, tea oil are more The combination of kind;It is furthermore preferred that the plants essential oil changes selected from citronella oil, Lavender, Geranium Essential, P-Cymene, fan One of essential oil, grapefruit essential oil or a variety of combinations.
In some embodiments, the plants essential oil be citronella oil, Lavender, Geranium Essential, P-Cymene, The composition of Rosemary Oil, grapefruit essential oil.
In some embodiments, the citronella oil, Lavender, Geranium Essential, P-Cymene, rosemary essence Oily, grapefruit essential oil weight ratio is 1:(0.1-1): (0.1-0.5): (0.5-1): (0.5-1): (0.1-0.5);Preferably, The citronella oil, Lavender, Geranium Essential, P-Cymene, Rosemary Oil, grapefruit essential oil weight ratio be 1: (0.3-0.7): (0.2-0.4): (0.7-0.8): (0.6-0.8): (0.2-0.4);It is furthermore preferred that the citronella oil, lavender Essential oil, Geranium Essential, P-Cymene, Rosemary Oil, grapefruit essential oil weight ratio be 1:0.5:0.3:0.75:0.7: 0.3。
No. CAS of the citronella oil is 8000-29-1;No. CAS of the Lavender is 8000-28-0;The day No. CAS of Zhu Kui essential oil is 8000-46-2;No. CAS of the P-Cymene is 8008-93-3;The CAS of the Rosemary Oil Number be 8000-25-7;No. CAS of the grapefruit essential oil is 90045-43-5.
In some embodiments, the solvent is water and/or small molecular alcohol;Preferably, the solvent is water and small point The combination of sub- alcohol.
In some embodiments, the weight ratio of the water and small molecular alcohol is 1:(0.5-1);Preferably, the water and The weight ratio of small molecular alcohol is 1:(0.6-0.9);It is furthermore preferred that the weight ratio of the water and small molecular alcohol is 1:0.75.
In some embodiments, the small molecular alcohol be selected from one of glycerol, propylene glycol, sorbierite, butanediol or Several combinations;Preferably, the small molecular alcohol is selected from the combination of one or more of glycerol, propylene glycol, sorbierite;It is preferred that , the small molecular alcohol is selected from the combination of one or more of glycerol, propylene glycol;It is further preferred that the small molecular alcohol For propylene glycol.
In some embodiments, heretofore described Chinese medicine composition the preparation method is as follows: by the original of composition Each plant extracts in material is added sequentially in agitated kettle, is stirred and heated to 65-80 DEG C, is added after mixing evenly molten Agent continues to stir evenly, be cooled to room temperature to get.
Preferably, the Chinese medicine composition the preparation method is as follows: by each plant extracts in the raw material of composition It is added sequentially in agitated kettle, is stirred and heated to 70 DEG C, adds solvent after mixing evenly, continue to stir evenly, be cooled to Room temperature to get.
The second aspect of the invention provides a kind of ointment comprising the Chinese medicine composition, by weight, raw material It includes at least, 40-60 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 0.1-2.5 parts of thickeners, 1-5 parts of stearic acid, 30-50 parts Glycerol.
In some preferred embodiments, the ointment, by weight, raw material includes at least, 50 parts of Chinese traditional medicine compositions Object, 0.7 part of dispersing agent, 1.5 parts of thickeners, 3 parts of stearic acid, 40 parts of glycerol.
In some embodiments, the ointment the preparation method is as follows:
Raw material in ointment: stearic acid, glycerol, Chinese medicine composition, dispersing agent, thickener is added sequentially to agitated kettle In, be stirred and heated to 75 DEG C, continue to stir evenly, be cooled to room temperature to get.
The third aspect of the invention provides a kind of lotion comprising the Chinese medicine composition, by weight, raw material It includes at least, 30-50 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 0.1-0.5 parts of thickeners, 1-5 parts of stearic acid, 30-50 parts Glycerol, 20-40 parts of deionized waters, 5-10 parts of surfactants.
In some preferred embodiments, the lotion, by weight, raw material includes at least, 40 parts of Chinese traditional medicine compositions Object, 0.8 part of dispersing agent, 0.3 part of thickener, 2.5 parts of stearic acid, 40 parts of glycerol, 30 parts of deionized waters, 7 parts of surfactants.
In some embodiments, the lotion the preparation method is as follows:
Raw material in lotion: stearic acid, glycerol, Chinese medicine composition, dispersing agent, thickener, surfactant is successively added Enter into agitated kettle, be stirred and heated to 75 DEG C, deionized water is added and continues to stir evenly, be cooled to room temperature to get.
The fourth aspect of the invention provides a kind of antipruritic water comprising the Chinese medicine composition, by weight, former Material includes at least, and 20-30 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 1-5 parts of stearic acid, 20-40 parts of glycerol, 40-60 parts are gone Ionized water, 5-10 parts of surfactants.
In some embodiments, the antipruritic water, by weight, raw material includes at least, 25 parts of Chinese medicine compositions, 0.7 part of dispersing agent, 3.5 parts of stearic acid, 30 parts of glycerol, 50 parts of deionized waters, 8 parts of surfactants.
In some embodiments, the antipruritic water the preparation method is as follows:
Raw material in lotion: stearic acid, glycerol, Chinese medicine composition, dispersing agent, surfactant is added sequentially to stir In pot, be stirred and heated to 90 DEG C, deionized water be added and continues to stir evenly, be cooled to room temperature to get.
The present invention is specifically described below by embodiment, following embodiment is only used for the present invention and does further Illustrate, can not be interpreted as the limitation that the present invention protects, professional and technical personnel in the field makes according to the content of foregoing invention Nonessential correction and adjustment, still fall within the range of protection of the invention.
Dispersing agent described in following embodiment is polyvinylpyrrolidone;The thickener is cetostearyl alcohol;The table Face activating agent is laureth sodium sulfovinate.
Embodiment 1-1
A kind of ointment comprising the Chinese medicine composition, by weight, raw material include 50 parts of Chinese medicine compositions, and 0.7 part Dispersing agent, 1.5 parts of thickeners, 3 parts of stearic acid, 40 parts of glycerol;
The ointment the preparation method is as follows:
Raw material in ointment: stearic acid, glycerol, Chinese medicine composition, dispersing agent, thickener is added sequentially to agitated kettle In, be stirred and heated to 75 DEG C, continue to stir evenly, be cooled to room temperature to get;
Chinese medicine composition described in the present embodiment, by weight percentage, the raw material of the composition include at least, 2% product Avenge careless extract, 8% purslane extract, 4.5% camomile extract, 1.8% hamamelis extract, the extraction of 3% honeysuckle Liquid, 2% Roselle flower extract, 8% haw thorn extract, 6% mint extract, 7% aloe extract, 3% glycine betaine, solvent Supply surplus;
The raw material of the composition also includes Fructus Monordicae extract, dandelion extract, the haw thorn extract, Siraitia grosvenorii Extract, dandelion extract weight ratio are 1:0.5:0.8;The raw material of the composition also includes that phytosterol, grape pip mention Take object, the phytosterol, grape seed extract, mint extract weight ratio be 1:0.3:0.75;The original of the composition The plants essential oil that material is also 5% comprising weight ratio, the plants essential oil are citronella oil, Lavender, Geranium Essential, folium artemisiae argyi Essential oil, Rosemary Oil, grapefruit essential oil composition, weight ratio 1:0.5:0.3:0.75:0.7:0.3;The solvent For the combination of water and propylene glycol, the weight ratio of the water and propylene glycol is 1:0.75;
The Chinese medicine composition the preparation method is as follows: each plant extracts in the raw material of composition is successively added Enter into agitated kettle, be stirred and heated to 70 DEG C, add solvent after mixing evenly, continues to stir evenly, be cooled to room temperature, i.e., ?.
Embodiment 1-2
A kind of ointment comprising the Chinese medicine composition, by weight, raw material include 40 parts of Chinese medicine compositions, and 0.5 part Dispersing agent, 0.1 part of thickener, 1 part of stearic acid, 30 parts of glycerol;
The ointment the preparation method is as follows:
Raw material in ointment: stearic acid, glycerol, Chinese medicine composition, dispersing agent, thickener is added sequentially to agitated kettle In, be stirred and heated to 75 DEG C, continue to stir evenly, be cooled to room temperature to get;
Chinese medicine composition described in the present embodiment, by weight percentage, the raw material of the composition include at least, 1% product The careless extract of snow, 5% purslane extract, 3% camomile extract, 2% hamamelis extract, 3% Flos Lonicerae extractive solution, 1% Roselle flower extract, 5% haw thorn extract, 3% mint extract, 5% aloe extract, 1% glycine betaine, solvent are mended Sufficient surplus;
The raw material of the composition also includes Fructus Monordicae extract, dandelion extract, the haw thorn extract, Siraitia grosvenorii Extract, dandelion extract weight ratio are 1:0.1:0.5;The raw material of the composition also includes that phytosterol, grape pip mention Take object, the phytosterol, grape seed extract, mint extract weight ratio be 1:0.1:0.5;The raw material of the composition The plants essential oil for being also 1% comprising weight ratio, the plants essential oil are citronella oil, Lavender, Geranium Essential, folium artemisiae argyi essence Oil, Rosemary Oil, grapefruit essential oil composition, weight ratio 1:0.1:0.1:0.5:0.5:0.1;The solvent is water With the combination of propylene glycol, the weight ratio of the water and propylene glycol is 1:0.5;
The Chinese medicine composition the preparation method is as follows: each plant extracts in the raw material of composition is successively added Enter into agitated kettle, be stirred and heated to 70 DEG C, add solvent after mixing evenly, continues to stir evenly, be cooled to room temperature, i.e., ?.
Embodiment 1-3
A kind of ointment comprising the Chinese medicine composition, by weight, raw material include 60 parts of Chinese medicine compositions, and 1 part point Powder, 2.5 parts of thickeners, 5 parts of stearic acid, 50 parts of glycerol;
The ointment the preparation method is as follows:
Raw material in ointment: stearic acid, glycerol, Chinese medicine composition, dispersing agent, thickener is added sequentially to agitated kettle In, be stirred and heated to 75 DEG C, continue to stir evenly, be cooled to room temperature to get;
Chinese medicine composition described in the present embodiment, by weight percentage, the raw material of the composition include at least, 3% product The careless extract of snow, 10% purslane extract, 6% camomile extract, 5% hamamelis extract, 10% Flos Lonicerae extractive solution, 3% Roselle flower extract, 10% haw thorn extract, 10% mint extract, 10% aloe extract, 5% glycine betaine, solvent Supply surplus;
The raw material of the composition also includes Fructus Monordicae extract, dandelion extract, the haw thorn extract, Siraitia grosvenorii Extract, dandelion extract weight ratio are 1:1:1;The raw material of the composition also includes phytosterol, grape seed extract, The phytosterol, grape seed extract, mint extract weight ratio be 1:0.5:1;The raw material of the composition also includes The plants essential oil that weight ratio is 10%, the plants essential oil are citronella oil, Lavender, Geranium Essential, P-Cymene, fan Repeatedly essential oil, grapefruit essential oil composition, weight ratio 1:1:0.5:1:1:0.5;The solvent is water and propylene glycol The weight ratio of combination, the water and propylene glycol is 1:1;
The Chinese medicine composition the preparation method is as follows: each plant extracts in the raw material of composition is successively added Enter into agitated kettle, be stirred and heated to 70 DEG C, add solvent after mixing evenly, continues to stir evenly, be cooled to room temperature, i.e., ?.
Embodiment 1-4
A kind of ointment comprising the Chinese medicine composition, by weight, raw material include 50 parts of Chinese medicine compositions, and 0.7 part Dispersing agent, 1.5 parts of thickeners, 3 parts of stearic acid, 40 parts of glycerol;
The ointment the preparation method is as follows:
Raw material in ointment: stearic acid, glycerol, Chinese medicine composition, dispersing agent, thickener is added sequentially to agitated kettle In, be stirred and heated to 75 DEG C, continue to stir evenly, be cooled to room temperature to get;
Chinese medicine composition described in the present embodiment, by weight percentage, the raw material of the composition include at least, and 1.5% Gotu Kola P.E, 6% purslane extract, 3.5% camomile extract, 2.5% hamamelis extract, 5% honeysuckle mention Take liquid, 1.5% Roselle flower extract, 6% haw thorn extract, 5% mint extract, 6% aloe extract, 2% glycine betaine, Solvent supplies surplus;
The raw material of the composition also includes Fructus Monordicae extract, dandelion extract, the haw thorn extract, Siraitia grosvenorii Extract, dandelion extract weight ratio are 1:0.3:0.6;The raw material of the composition also includes that phytosterol, grape pip mention Take object, the phytosterol, grape seed extract, mint extract weight ratio be 1:0.2:0.6;The raw material of the composition The plants essential oil for being also 3% comprising weight ratio, the plants essential oil are citronella oil, Lavender, Geranium Essential, folium artemisiae argyi essence Oil, Rosemary Oil, grapefruit essential oil composition, weight ratio 1:0.3:0.2:0.7:0.6:0.2;The solvent is water With the combination of propylene glycol, the weight ratio of the water and propylene glycol is 1:0.6;
The Chinese medicine composition the preparation method is as follows: each plant extracts in the raw material of composition is successively added Enter into agitated kettle, be stirred and heated to 70 DEG C, add solvent after mixing evenly, continues to stir evenly, be cooled to room temperature, i.e., ?.
Embodiment 1-5
A kind of ointment comprising the Chinese medicine composition, by weight, raw material include 50 parts of Chinese medicine compositions, and 0.7 part Dispersing agent, 1.5 parts of thickeners, 3 parts of stearic acid, 40 parts of glycerol;
The ointment the preparation method is as follows:
Raw material in ointment: stearic acid, glycerol, Chinese medicine composition, dispersing agent, thickener is added sequentially to agitated kettle In, be stirred and heated to 75 DEG C, continue to stir evenly, be cooled to room temperature to get;
Chinese medicine composition described in the present embodiment, by weight percentage, the raw material of the composition include at least, and 2.5% Gotu Kola P.E, 9% purslane extract, 5.5% camomile extract, 3.5% hamamelis extract, 8% honeysuckle mention Take liquid, 2.5% Roselle flower extract, 9% haw thorn extract, 7% mint extract, 8% aloe extract, 4% glycine betaine, Solvent supplies surplus;
The raw material of the composition also includes Fructus Monordicae extract, dandelion extract, the haw thorn extract, Siraitia grosvenorii Extract, dandelion extract weight ratio are 1:0.7:0.9;The raw material of the composition also includes that phytosterol, grape pip mention Take object, the phytosterol, grape seed extract, mint extract weight ratio be 1:0.4:0.9;The raw material of the composition The plants essential oil for being also 7% comprising weight ratio, the plants essential oil are citronella oil, Lavender, Geranium Essential, folium artemisiae argyi essence Oil, Rosemary Oil, grapefruit essential oil composition, weight ratio 1:0.7:0.4:0.8:0.8:0.4;The solvent is water With the combination of propylene glycol, the weight ratio of the water and propylene glycol is 1:0.9;
The Chinese medicine composition the preparation method is as follows: each plant extracts in the raw material of composition is successively added Enter into agitated kettle, be stirred and heated to 70 DEG C, add solvent after mixing evenly, continues to stir evenly, be cooled to room temperature, i.e., ?.
Embodiment 1-6
A kind of ointment comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 1-1 exist In without containing Fructus Monordicae extract.
Embodiment 1-7
A kind of ointment comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 1-1 exist In without containing haw thorn extract.
Embodiment 1-8
A kind of ointment comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 1-1 exist In without containing grape seed extract.
Embodiment 1-9
A kind of ointment comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 1-1 exist In the phytosterol, grape seed extract, mint extract weight ratio be 1:0.05:0.1.
Embodiment 1-10
A kind of ointment comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 1-1 exist In the phytosterol, grape seed extract, mint extract weight ratio be 1:1:0.1.
Embodiment 2-1
A kind of lotion comprising the Chinese medicine composition, by weight, raw material include 40 parts of Chinese medicine compositions, and 0.8 part Dispersing agent, 0.3 part of thickener, 2.5 parts of stearic acid, 40 parts of glycerol, 30 parts of deionized waters, 7 parts of surfactants;
The lotion the preparation method is as follows:
Raw material in lotion: stearic acid, glycerol, Chinese medicine composition, dispersing agent, thickener, surfactant is successively added Enter into agitated kettle, be stirred and heated to 75 DEG C, deionized water is added and continues to stir evenly, be cooled to room temperature to get;
Chinese medicine composition described in the present embodiment, by weight percentage, the raw material of the composition include at least, 2% product Avenge careless extract, 8% purslane extract, 4.5% camomile extract, 1.8% hamamelis extract, the extraction of 3% honeysuckle Liquid, 2% Roselle flower extract, 8% haw thorn extract, 6% mint extract, 7% aloe extract, 3% glycine betaine, solvent Supply surplus;
The raw material of the composition also includes Fructus Monordicae extract, dandelion extract, the haw thorn extract, Siraitia grosvenorii Extract, dandelion extract weight ratio are 1:0.5:0.8;The raw material of the composition also includes that phytosterol, grape pip mention Take object, the phytosterol, grape seed extract, mint extract weight ratio be 1:0.3:0.75;The original of the composition The plants essential oil that material is also 5% comprising weight ratio, the plants essential oil are citronella oil, Lavender, Geranium Essential, folium artemisiae argyi Essential oil, Rosemary Oil, grapefruit essential oil composition, weight ratio 1:0.5:0.3:0.75:0.7:0.3;The solvent For the combination of water and propylene glycol, the weight ratio of the water and propylene glycol is 1:0.75;
The Chinese medicine composition the preparation method is as follows: each plant extracts in the raw material of composition is successively added Enter into agitated kettle, be stirred and heated to 70 DEG C, add solvent after mixing evenly, continues to stir evenly, be cooled to room temperature, i.e., ?.
Embodiment 2-2
A kind of lotion comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 2-1 exist In, by weight, raw material includes at least, 30 parts of Chinese medicine compositions, 0.5 part of dispersing agent, 0.1 part of thickener, 1 part of stearic acid, 30 parts of glycerol, 20 parts of deionized waters, 5 parts of surfactants.
Embodiment 2-3
A kind of lotion comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 2-1 exist In, by weight, raw material includes at least, 50 parts of Chinese medicine compositions, 1 part of dispersing agent, 0.5 part of thickener, 5 parts of stearic acid, and 50 Part glycerol, 40 parts of deionized waters, 10 parts of surfactants.
Embodiment 3-1
A kind of lotion comprising the Chinese medicine composition, by weight, raw material include 25 parts of Chinese medicine compositions, and 0.7 part Dispersing agent, 3.5 parts of stearic acid, 30 parts of glycerol, 50 parts of deionized waters, 8 parts of surfactants;
The lotion the preparation method is as follows:
Stearic acid, glycerol, Chinese medicine composition, dispersing agent, surfactant are added sequentially in agitated kettle, are stirred and are heated To 90 DEG C, be added deionized water continue to stir evenly, be cooled to room temperature to get;
Chinese medicine composition described in the present embodiment, by weight percentage, the raw material of the composition include at least, 2% product Avenge careless extract, 8% purslane extract, 4.5% camomile extract, 1.8% hamamelis extract, the extraction of 3% honeysuckle Liquid, 2% Roselle flower extract, 8% haw thorn extract, 6% mint extract, 7% aloe extract, 3% glycine betaine, solvent Supply surplus;
The raw material of the composition also includes Fructus Monordicae extract, dandelion extract, the haw thorn extract, Siraitia grosvenorii Extract, dandelion extract weight ratio are 1:0.5:0.8;The raw material of the composition also includes that phytosterol, grape pip mention Take object, the phytosterol, grape seed extract, mint extract weight ratio be 1:0.3:0.75;The original of the composition The plants essential oil that material is also 5% comprising weight ratio, the plants essential oil are citronella oil, Lavender, Geranium Essential, folium artemisiae argyi Essential oil, Rosemary Oil, grapefruit essential oil composition, weight ratio 1:0.5:0.3:0.75:0.7:0.3;The solvent For the combination of water and propylene glycol, the weight ratio of the water and propylene glycol is 1:0.75;
The Chinese medicine composition the preparation method is as follows: each plant extracts in the raw material of composition is successively added Enter into agitated kettle, be stirred and heated to 70 DEG C, add solvent after mixing evenly, continues to stir evenly, be cooled to room temperature, i.e., ?.
Embodiment 3-2
A kind of lotion comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 2-1 exist In, by weight, 20 parts of Chinese medicine compositions, 0.5 part of dispersing agent, 1 part of stearic acid, 20 parts of glycerol, 40 parts of deionized waters, 5 parts Surfactant.
Embodiment 3-3
A kind of lotion comprising Chinese medicine composition is present embodiments provided, the distinctive points of the present embodiment and embodiment 2-1 exist In, by weight, 30 parts of Chinese medicine compositions, 1 part of dispersing agent, 5 parts of stearic acid, 40 parts of glycerol, 60 parts of deionized waters, 10 parts of tables Face activating agent.
Performance test
1. antipruritic test
Test method: volunteer 140 with serious itching of the scalp symptom that the age is 40~50 years old are selected, wherein female Property 52 people, volunteer is randomly divided into 7 groups by 88 people of male, and every group of 20 people use 1~embodiment of embodiment 5, comparative example respectively Anti-dandruff and itching-relieving composition and commercially available anti-dandruff and itching-relieving liquid.
Application method are as follows: after hair washing, be applied at scalp, 1 time a day, each 3ml~5ml is for 3 weeks.
Appraisal procedure: by the way of questionnaire survey, understand using after 3 weeks, subject changes product using rear anti-dandruff The evaluation of kind situation.
Evaluation result is divided into: (the example)/tested number (example) × 100% of significant effective rate=clearly.
Effect is unobvious: significant effective rate is 0-20% range;
Effect is general: significant effective rate is 20-40% range;
More apparent: significant effective rate is 40-60% range;
Clearly: significant effective rate is 60-100% range.
Test result is as shown in table 1.
The antipruritic evaluation of table 1
Embodiment Antipruritic evaluation Embodiment Antipruritic evaluation
Embodiment 1-1 Clearly Embodiment 1-7 Effect is unobvious
Embodiment 1-2 Effect is general Embodiment 1-8 Effect is unobvious
Embodiment 1-3 It is more apparent Embodiment 1-9 Effect is unobvious
Embodiment 1-4 It is more apparent Embodiment 1-10 Effect is unobvious
Embodiment 1-5 Effect is general Embodiment 2-1 Clearly
Embodiment 1-6 Effect is unobvious Embodiment 2-2 It is more apparent
Example above-mentioned is merely illustrative, some features of the feature for explaining the disclosure.The attached claims It is intended to the range as wide as possible for requiring to be contemplated that, and embodiments as presented herein is only according to all possible embodiment Combined selection embodiment explanation.Therefore, the purpose of applicant is that the attached claims are not illustrated the present invention Feature exemplary selectional restriction.And the progress in science and technology will be formed language express it is inaccurate due to and not The possible equivalent being presently considered or son replacement, and these variations should also be interpreted in the conceived case by appended Claim covering.

Claims (10)

1. a kind of anti-bacterial, anti-itching Chinese medicine composition, which is characterized in that by weight percentage, the raw material of the composition at least wraps Contain, 1-3% Gotu Kola P.E, 5-10% purslane extract, 3-6% camomile extract, 2-5% hamamelis extract, 3-10% Flos Lonicerae extractive solution, 1-3% Roselle flower extract, 5-10% haw thorn extract, 3-10% mint extract, 5- 10% aloe extract, 1-5% glycine betaine, solvent supply surplus.
2. Chinese medicine composition as described in claim 1, which is characterized in that by weight percentage, the raw material of the composition It includes at least, 1.5-2.5% Gotu Kola P.E, 6-9% purslane extract, 3.5-5.5% camomile extract, 1.5- 2% hamamelis extract, 2-4% Flos Lonicerae extractive solution, 1.5-2.5% Roselle flower extract, 6-9% haw thorn extract, 5- 7% mint extract, 2-4% glycine betaine, solvent supply surplus.
3. such as the described in any item Chinese medicine compositions of claim 1-2, which is characterized in that the raw material of the composition also includes sieve Chinese berry extract, dandelion extract;The haw thorn extract, Fructus Monordicae extract, dandelion extract weight ratio are 1: (0.1-1): (0.5-1).
4. such as the described in any item Chinese medicine compositions of claim 1-2, which is characterized in that the raw material of the composition also includes weight Amount is than the plants essential oil for 1-10%;The plants essential oil is selected from citronella oil, spearmint oil, curcuma oil, Lavender, India Certain herbaceous plants with big flowers essential oil, P-Cymene, eucalyptus citriodora essential oil, clove oil, camellia seed essential oil, Catnip essential oil, thyme essential oil, rosemary essence Oil, castor oil, Litsea pungens essential oil, Lavender, Asian puccoon essential oil, fragrant Fructus Perillae quintessence oil, spearmint essential oil, pot marigold essential oil, snow Loose essential oil, juniper berry essential oil, motherwort essential oil, Cortex Eucommiae essential oil, refined jasmine oil, Rosa Damascana, osmanthus essential oil, lemon grass (Cymbopogon citratus) essential oil, Tea oil, one of grapefruit essential oil or a variety of combinations.
5. such as the described in any item Chinese medicine compositions of claim 1-2, which is characterized in that the solvent is water and/or small molecule Alcohol.
6. such as the described in any item Chinese medicine compositions of claim 1-2, which is characterized in that the raw material of the composition also includes to plant Object sterol, grape seed extract;The phytosterol, grape seed extract, mint extract weight ratio be 1:(0.1- 0.5): (0.5-1).
7. Chinese medicine composition as claimed in claim 4, which is characterized in that the plants essential oil be citronella oil, Lavender, Geranium Essential, P-Cymene, Rosemary Oil, grapefruit essential oil composition;The citronella oil, Lavender, India Certain herbaceous plants with big flowers essential oil, P-Cymene, Rosemary Oil, grapefruit essential oil weight ratio be 1:(0.1-1): (0.1-0.5): (0.5-1): (0.5-1): (0.1-0.5).
8. a kind of ointment comprising the Chinese medicine composition as described in claim any one of 1-7, which is characterized in that by weight, Raw material includes at least, 40-60 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 0.1-2.5 parts of thickeners, 1-5 parts of stearic acid, 30- 50 parts of glycerol.
9. a kind of lotion comprising the Chinese medicine composition as described in claim any one of 1-7, which is characterized in that by weight, Raw material includes at least, 30-50 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 0.1-0.5 parts of thickeners, 1-5 parts of stearic acid, 30- 50 parts of glycerol, 20-40 parts of deionized waters, 5-10 parts of surfactants.
10. a kind of antipruritic water comprising the Chinese medicine composition as described in claim any one of 1-7, which is characterized in that by weight Meter, raw material include at least, 20-30 parts of Chinese medicine compositions, 0.5-1 parts of dispersing agents, 1-5 parts of stearic acid, 20-40 parts of glycerol, 40-60 Part deionized water, 5-10 parts of surfactants.
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CN112494542A (en) * 2020-12-23 2021-03-16 青岛初方美即生物制药有限公司 Biological agent for treating skin diseases and preparation method thereof
CN113244382A (en) * 2021-06-11 2021-08-13 江南大学 Itching-relieving and swelling-diminishing composition as well as preparation method and application thereof
CN114225086A (en) * 2021-12-29 2022-03-25 安徽全民环保科技有限公司 Natural plant type deodorizing and insect expelling preparation and preparation method thereof
CN114225086B (en) * 2021-12-29 2024-02-02 安徽全民环保科技有限公司 Natural plant type deodorizing and insect-repellent preparation and preparation method thereof
CN115300419A (en) * 2022-08-10 2022-11-08 北京思邈香草生物科技有限公司 Composite vegetable oil with mosquito-repelling, itching-relieving, bacterium-inhibiting and swelling-diminishing effects and preparation method and application thereof
CN115300419B (en) * 2022-08-10 2023-05-26 北京思邈香草生物科技有限公司 Compound vegetable oil with effects of repelling mosquitoes, relieving itching, inhibiting bacteria and relieving swelling, and preparation method and application thereof

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Application publication date: 20190820