CN110141395B - Auxiliary device for intravenous injection of rat tail - Google Patents

Auxiliary device for intravenous injection of rat tail Download PDF

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Publication number
CN110141395B
CN110141395B CN201910499099.7A CN201910499099A CN110141395B CN 110141395 B CN110141395 B CN 110141395B CN 201910499099 A CN201910499099 A CN 201910499099A CN 110141395 B CN110141395 B CN 110141395B
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rotating wheel
needle
rat tail
bottom plate
fixed
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CN110141395A (en
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赵相轩
孙洪赞
卢再鸣
石喻
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Shengjing Hospital of China Medical University
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Shengjing Hospital of China Medical University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Husbandry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A rat tail intravenous injection auxiliary device belongs to the technical field of medical experiment auxiliary equipment, and particularly relates to a rat tail intravenous needle penetration injection auxiliary device. The auxiliary device for the rat tail injection is convenient to use and improves the success rate of rat tail puncture. The invention comprises a bottom plate, wherein a rat tail fixing component and a puncture component are arranged on the bottom plate, and the invention is characterized in that: the rat tail fixing assembly comprises a fixed rotating wheel arranged on a bottom plate, a movable rotating wheel is arranged on the side of the fixed rotating wheel on the bottom plate through a first chute, and a reset spring for enabling the movable rotating wheel to lean against the fixed wheel is arranged on the movable rotating wheel; the needle inserting assembly comprises a rotating shaft arranged on the bottom plate, a sliding block capable of transversely sliding along the rotating shaft and rotating along with the rotating shaft is arranged on the rotating shaft, a needle cylinder is arranged below the sliding block, and a needle head sliding along the needle cylinder is arranged in the needle cylinder; the needle cylinder corresponds to the fixed rotating wheel and the movable rotating wheel; the fixed rotating wheel is connected with the rotating shaft through a gear transmission assembly.

Description

Auxiliary device for intravenous injection of rat tail
Technical Field
The invention belongs to the technical field of auxiliary equipment for medical experiments, and particularly relates to an auxiliary device for puncture injection of a tail vein needle.
Background
In medical research, rats (e.g., SD rats, wistar rats, etc.), mice (e.g., kunming mice), and humans belong to the same species of mammal, and have similar organ structures and genes as humans. The plant growth regulator has the advantages of small mass, mild and smooth sex, fast growth, short propagation period, strong disease resistance and the like, and is selected as an animal model research object in a laboratory. By carrying out pharmacological, toxicological and tumor experiments and other various acute and chronic reaction experiments on rats or mice, the method has the advantages of obtaining the attention achievement accepted by the medical community, greatly promoting the progress and development of human medical level and benefiting mankind. In practice, the current administration modes of the animal model of the mice are gastric lavage administration, intraperitoneal injection, subcutaneous injection, tail vein injection and the like. The tail intravenous injection (also called as tail vein puncture) is the most important administration method, and compared with other administration modes, the method has the advantages of accurate and reliable pharmacological experiment results, closest to the human body administration mode, and capability of saving the dosage and the number of experimental animals. However, in practice, it has been found that since the tail vein is thin, the tail vein is buried deeply, and particularly, since the tail cuticle and vein of the rat are thin, successful puncture is very difficult, and particularly, the tail vein is square or bamboo-shaped, and the puncture administration success rate is very low. Thus, the experimenters, especially the beginners, need to spend a great deal of effort to practice the 'rat tail vein puncture', but still have high failure rate, waste of substances and time is caused, the problems plague basic and clinical testers, and the progress of related medical tests is hindered and delayed. It is therefore highly desirable to find a safer, more reliable method of venipuncture from the tail of the rat with a higher success rate. The semi-automatic puncture device for the tail vein successfully solves the problems. The needle feeding device has the characteristics of economy, practicality, stable structure, easy operation, high needle feeding success rate, difficult shifting and falling, accurate administration and the like. The technical device utilizes the characteristics of different tail parts and other body parts: the skin is exposed, regular convex-concave ring-shaped structures exist on the surface, the position of the needle head is calculated in a stepping mode through the hinged gear, angle adjustment is carried out, the needle is shot into the needle by means of shooting, and the needle head is accurately positioned, mechanically pierced into the needle and stably kept by the aid of the structure that the needle is successfully shot into the observation window is verified. The device successfully solves the problems of difficult medication and even medication failure caused by inaccurate venipuncture of the mice, can be started by simple learning, has high repeatability, and provides guarantee for obtaining reliable experimental data and good experimental effect in animal experiments.
Disclosure of Invention
The invention aims at the problems and provides the auxiliary device for the rat tail injection, which is convenient to use and improves the success rate of rat tail puncture.
In order to achieve the above purpose, the invention adopts the following technical scheme that the invention comprises a bottom plate, and the bottom plate is provided with a rat tail fixing component and a puncture component, and is characterized in that: the rat tail fixing assembly comprises a fixed rotating wheel arranged on a bottom plate, a movable rotating wheel is arranged on the side of the fixed rotating wheel on the bottom plate through a first chute, and a reset spring for enabling the movable rotating wheel to lean against the fixed wheel is arranged on the movable rotating wheel; the needle inserting assembly comprises a rotating shaft arranged on the bottom plate, a sliding block capable of transversely sliding along the rotating shaft and rotating along with the rotating shaft is arranged on the rotating shaft, a needle cylinder is arranged below the sliding block, and a needle head sliding along the needle cylinder is arranged in the needle cylinder; the needle cylinder corresponds to the fixed rotating wheel and the movable rotating wheel; the fixed rotating wheel is connected with the rotating shaft through a gear transmission assembly.
As a preferable scheme of the invention, tooth grooves are arranged on the surfaces of the fixed rotating wheel and the movable rotating wheel.
As another preferable scheme of the invention, a thrust spring of a needle is arranged in the needle cylinder, a wedge-shaped card matched with the needle cylinder is arranged on the side surface of the needle cylinder, and a button is arranged on the needle cylinder corresponding to the wedge-shaped card; the surface of the needle cylinder is provided with an observation slide rail corresponding to the needle head, and the needle head is provided with a bump matched with the observation slide rail.
As a third preferred scheme of the invention, the movable rotating wheel is connected with a driving rack below the bottom plate; the driving rack is connected with the driven rack through a gear set, and a shifting fork matched with the sliding block is arranged on the driven rack.
Further, the gear set comprises a driving gear matched with the driving rack and a driven gear matched with the driven rack; the transmission ratio of the driving gear and the driven gear enables the moving distance of the driving rack to be twice as long as the moving distance of the driven rack.
As a fourth preferred scheme of the invention, a vertical plate is arranged on the bottom plate, and a rat tail inlet is arranged on the vertical plate corresponding to the space between the fixed rotating wheel and the driven rotating wheel; a rat cylinder is arranged on the bottom plate through a longitudinal slideway, and a rat tail outlet is arranged on the rat cylinder corresponding to the rat tail inlet.
The invention has the beneficial effects that: 1. according to the invention, the rat tail clamp can be fixed between the fixed rotating wheel and the movable rotating wheel through the cooperation of the fixed rotating wheel and the movable rotating wheel; meanwhile, the angle of the needle cylinder can be automatically adjusted through the gear transmission assembly; after the angle of the needle cylinder is adjusted, the function of automatically adjusting the angle can be realized; the needle outlet depth of the needle head is fixed due to the limitation of the needle cylinder, so that the function of automatic needle inlet is realized; greatly reduces the risk of the test mice being pricked.
2. By arranging tooth grooves on the fixed rotating wheel and the movable rotating wheel, the tooth grooves can be matched with the bone joint of the rat tail to rotate, so that the effect of precisely controlling the angle of the needle cylinder is achieved.
3. Due to the structural characteristics of the needle cylinder and the needle head, the needle head can automatically advance the needle under the action of the thrust spring by pressing the button, so that the error caused by manual needle advance of a person is avoided.
4. According to the invention, through the cooperation of the driving rack, the gear set and the driven rack, the transverse moving distance of the sliding block is half of that of the movable rotating wheel, so that the needle head is ensured to be always right against the center of the rat tail, and the pricking deviation is avoided.
5. The invention is provided with the mouse cylinder, which can fix the mouse and avoid the mouse from being tampered with or biting an operator.
Drawings
Fig. 1 is a schematic structural view of the present invention.
Fig. 2 is a front view of the present invention.
Fig. 3 is a bottom view of the present invention.
Fig. 4 is a top view of the present invention.
Fig. 5 is a cross-sectional view A-A of fig. 4.
Fig. 6 is a B-B cross-sectional view of fig. 5.
Fig. 7 is a schematic view of another angle of the present invention.
In the drawing, a rotating shaft 1, a sliding block 2, a movable rotating wheel 3, a fixed rotating wheel 4, a reset spring 5, a guide block 6, a guide groove 7, a mouse barrel 8, a rat tail outlet 9, a fixed beam 10, a horizontal umbrella tooth 11, a vertical plate 12, a vertical umbrella tooth 13, a toothed belt 14, a driven straight tooth 15, a shifting fork 16, a needle cylinder 17, a button 18, a needle 19, a bottom plate 20, a fixed straight tooth 21, a longitudinal slideway 22, a driving rack 23, a driving gear 24, a driven gear 25, a driven rack 26, a limiting guide shaft 27, a thrust spring 28, a wedge-shaped card 29, an observation slideway 30 and a convex block 31 are arranged.
Detailed Description
The invention comprises a bottom plate 20, wherein a rat tail fixing component and a puncture component are arranged on the bottom plate 20, and the invention is characterized in that: the rat tail fixing assembly comprises a fixed rotating wheel 4 arranged on a bottom plate 20, a movable rotating wheel 3 is arranged on the side of the fixed rotating wheel 4 on the bottom plate 20 through a first chute, and a reset spring 5 for enabling the movable rotating wheel 3 to lean against the fixed wheel is arranged on the movable rotating wheel 3; the needle insertion assembly comprises a rotating shaft 1 arranged on a bottom plate 20, a sliding block 2 capable of transversely sliding along the rotating shaft 1 and rotating along with the rotating shaft 1 is arranged on the rotating shaft 1, a needle cylinder 17 is arranged below the sliding block 2, and a needle 19 sliding along the needle cylinder 17 is arranged in the needle cylinder 17; the needle cylinder 17 corresponds to the fixed rotating wheel 4 and the movable rotating wheel 3; the fixed rotating wheel 4 is connected with the rotating shaft 1 through a gear transmission assembly.
The gear transmission assembly comprises a horizontal bevel gear 11 fixedly connected with the shaft of the fixed rotating wheel 4, and the horizontal bevel gear 11 is matched with a fixed vertical bevel gear 13; the vertical umbrella teeth 13 are provided with fixed straight teeth, and the fixed straight teeth 21 are connected with driven straight teeth 15 on the rotating shaft 1 through a toothed belt 14.
The base plate 20 may be provided with a tensioner (not shown) for the toothed belt 14.
As a preferable scheme of the invention, tooth grooves are arranged on the surfaces of the fixed rotating wheel 4 and the movable rotating wheel 3.
As another preferable scheme of the invention, a thrust spring 28 of the needle 19 is arranged in the needle cylinder 17, a wedge-shaped card 29 matched with the needle cylinder 17 is arranged on the side surface of the needle 19, and a button 18 is arranged on the needle cylinder 17 corresponding to the wedge-shaped card 29; the surface of the needle cylinder 17 is provided with an observation slide corresponding to the needle 19, and the needle 19 is provided with a bump matched with the observation slide.
As a third preferred scheme of the invention, the movable rotating wheel 3 is connected with a driving rack 23 below the bottom plate 20; the driving rack 23 is connected with a driven rack 26 through a gear set, and a shifting fork 16 matched with the sliding block 2 is arranged on the driven rack 26.
Further, the gear set includes a driving gear 24 engaged with the driving rack 23 and a driven gear 25 engaged with the driven rack 26; the transmission ratio of the driving gear 24 to the driven gear 25 makes the moving distance of the driving rack 23 twice as long as the moving distance of the driven rack 26.
The base plate 20 is provided with a limiting guide shaft 27 matched with the driving rack 23 and the driven rack 26.
The bottom plate 20 is provided with a fixed beam 10, a guide groove 7 is arranged in the fixed beam 10, the shaft of the movable rotating wheel 3 is connected with a guide block 6, and the guide block 6 is arranged in the guide groove 7; the return spring 5 is arranged between the guide block 6 and the fixed beam 10.
As a fourth preferred solution of the present invention, the bottom plate 20 is provided with a vertical plate 12, and a rat tail inlet is arranged on the vertical plate 12 corresponding to the space between the fixed runner 4 and the driven runner; a rat barrel 8 is arranged on the bottom plate 20 through a longitudinal slideway 22, and a rat tail outlet 9 is arranged on the rat barrel 8 corresponding to the rat tail inlet.
The whole device can be arranged in a shell (not shown), and the shell can protect components such as a driving rack 23 and the like at the bottom of the bottom plate 20; the shell can also be used for fixing the rotating shaft 1, the fixed beam 10 and other parts.
When the invention is used, firstly, the angle of the needle cylinder 17 is adjusted according to the condition of the experimental mouse; then the lug in the observation slide way is pulled to enable the needle 19 to overcome the thrust of the thrust spring 28; when moved into position, the wedge-shaped card 29 on the needle 19 springs out of engagement with the barrel 17 and the needle 19 is secured. Then putting the mouse into a mouse cylinder 8, enabling the tail of the mouse to extend out of a rat tail outlet hole 9 and enter a rat tail inlet hole, enabling bone joints of the rat tail to be matched with a fixed rotating wheel 4 and a driven rotating wheel in the rat tail inlet process, enabling the fixed rotating wheel 4 to rotate, driving a rotating shaft 1 to rotate through a gear transmission assembly, enabling a sliding block 2 to rotate along with the rotating shaft 1, enabling a needle cylinder 17 below the sliding block 2 to rotate along with the rotating shaft, and accordingly changing the needle inlet angle of the needle cylinder 17; when the proper position is reached, the button 18 is pressed, the button 18 pushes the wedge-shaped card 29 to retract, the locking structure of the wedge-shaped card 29 and the needle cylinder 17 is released, the needle 19 is ejected out by the thrust spring 28, and the needle is penetrated into the blood vessel of the rat tail, so that the needle insertion work is completed. An operator can observe the needle 19 by utilizing the observation slide way, if blood return does not occur, the needle 19 can be retracted after the needle insertion failure is indicated, and then the rat tail is rebunched after going deep into a condyle, so that the fault tolerance rate is improved.
The device has the following characteristics: 1. the invention can be divided into two types of special rat and mouse. 2. The invention has the observation slide way, blood can be seen in the observation slide way after successful needle insertion, meanwhile, the needle tube can be internally provided with the one-way valve, and the one-way valve system is closed after the blood is refluxed, so that the blood is prevented from flowing out. The one-way valve can be inserted into the needle for drug administration. The needle is automatically closed after withdrawal. Preventing contamination and drug leakage. 3. The invention can be reused, and the alcohol can be used for disinfection, thus preventing cross infection. 4. The needle cylinder and the needle head can be made of glass materials or transparent plastic materials, and the rest can be made of stainless steel materials, so that the needle cylinder and the needle head are durable and corrosion-resistant. 5. The invention does not need an external power supply, is a pure mechanical device, does not consume energy and is environment-friendly.
It should be understood that the foregoing detailed description of the present invention is provided for illustration only and is not limited to the technical solutions described in the embodiments of the present invention, and those skilled in the art should understand that the present invention may be modified or substituted for the same technical effects; as long as the use requirement is met, the invention is within the protection scope of the invention.

Claims (6)

1. The utility model provides a rat tail injection auxiliary device, includes bottom plate (20), is provided with rat tail fixed subassembly and puncture subassembly on bottom plate (20), its characterized in that: the rat tail fixing assembly comprises a fixed rotating wheel (4) arranged on a bottom plate (20), a movable rotating wheel (3) is arranged on the side of the fixed rotating wheel (4) on the bottom plate (20) through a first chute, and a reset spring (5) for enabling the movable rotating wheel (3) to lean against the fixed wheel is arranged on the movable rotating wheel (3); the needle insertion assembly comprises a rotating shaft (1) arranged on a bottom plate (20), a sliding block (2) which can transversely slide along the rotating shaft (1) and rotate along with the rotating shaft (1) is arranged on the rotating shaft (1), a needle cylinder (17) is arranged below the sliding block (2), and a needle head (19) which slides along the needle cylinder (17) is arranged in the needle cylinder (17); the needle cylinder (17) corresponds to the fixed rotating wheel (4) and the movable rotating wheel (3); the fixed rotating wheel (4) is connected with the rotating shaft (1) through a gear transmission assembly; tooth grooves are formed in the surfaces of the fixed rotating wheel (4) and the movable rotating wheel (3); a thrust spring (28) of a needle head (19) is arranged in the needle cylinder (17), a wedge-shaped card (29) matched with the needle cylinder (17) is arranged on the side surface of the needle head (19), and a button (18) is arranged on the needle cylinder (17) corresponding to the wedge-shaped card (29); the surface of the needle cylinder (17) is provided with an observation slide way corresponding to the needle head (19), and the needle head (19) is provided with a bump matched with the observation slide way; the movable rotating wheel (3) is connected with a driving rack (23) below the bottom plate (20); the driving rack (23) is connected with the driven rack (26) through a gear set, and a shifting fork (16) matched with the sliding block (2) is arranged on the driven rack (26); the gear set comprises a driving gear (24) matched with the driving rack (23) and a driven gear (25) matched with the driven rack (26); the transmission ratio of the driving gear (24) and the driven gear (25) enables the moving distance of the driving rack (23) to be twice as long as the moving distance of the driven rack (26).
2. The rat tail injection aid of claim 1, wherein: the gear transmission assembly comprises a horizontal bevel gear (11) fixedly connected with the shaft of the fixed rotating wheel (4), and the horizontal bevel gear (11) is matched with a fixed vertical bevel gear (13); the vertical umbrella teeth (13) are provided with fixed straight teeth, and the fixed straight teeth (21) are connected with driven straight teeth (15) on the rotating shaft (1) through toothed belts (14).
3. The rat tail injection aid of claim 1, wherein: and a limiting guide shaft (27) matched with the driving rack (23) and the driven rack (26) is arranged on the bottom plate (20).
4. The rat tail injection aid of claim 1, wherein: the bottom plate (20) is provided with a fixed beam (10), a guide groove (7) is formed in the fixed beam (10), the shaft of the movable rotating wheel (3) is connected with a guide block (6), and the guide block (6) is arranged in the guide groove (7); the return spring (5) is arranged between the guide block (6) and the fixed beam (10).
5. The rat tail injection aid of claim 1, wherein: a vertical plate (12) is arranged on the bottom plate (20), and a rat tail inlet is arranged on the vertical plate (12) corresponding to the space between the fixed rotating wheel (4) and the driven rotating wheel; a rat barrel (8) is arranged on the bottom plate (20) through a longitudinal slideway (22), and a rat tail outlet (9) is arranged on the rat barrel (8) corresponding to the rat tail inlet.
6. The rat tail injection aid of claim 1, wherein: a one-way valve is arranged in the needle tube.
CN201910499099.7A 2019-06-11 2019-06-11 Auxiliary device for intravenous injection of rat tail Active CN110141395B (en)

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CN201910499099.7A CN110141395B (en) 2019-06-11 2019-06-11 Auxiliary device for intravenous injection of rat tail

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CN110141395B true CN110141395B (en) 2023-11-28

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110721002B (en) * 2019-09-09 2021-09-14 西安医学院 Device of blood glucose is surveyed with blood sampling of mouse tail vein for experiments

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CN210990901U (en) * 2019-06-11 2020-07-14 中国医科大学附属盛京医院 Auxiliary device for intravenous injection of rat tail

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