CN110721002B - Device of blood glucose is surveyed with blood sampling of mouse tail vein for experiments - Google Patents
Device of blood glucose is surveyed with blood sampling of mouse tail vein for experiments Download PDFInfo
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- CN110721002B CN110721002B CN201910866130.6A CN201910866130A CN110721002B CN 110721002 B CN110721002 B CN 110721002B CN 201910866130 A CN201910866130 A CN 201910866130A CN 110721002 B CN110721002 B CN 110721002B
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- blood
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- blood sampling
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- needle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15146—Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
Abstract
The invention discloses a device for measuring blood sugar by taking blood from tail veins of an experimental mouse, which comprises a bottom plate, wherein baffle plates are arranged around the bottom plate, a mouse positioning box is arranged on the bottom plate, a detachable box cover is arranged at the top of the mouse positioning box, a plurality of mouse tail extending holes are arranged on one side of the bottom of the mouse positioning box, and a blood taking mechanism is also arranged on the bottom plate. The invention solves the problem of low blood sampling efficiency of the traditional blood sampling mode, can effectively relieve the stress reaction of mice and improves the preparation rate of blood sugar measurement.
Description
Technical Field
The invention belongs to the technical field of blood sampling equipment, and relates to a device for measuring blood sugar by sampling blood from tail veins of an experimental mouse.
Background
The in-process does not have corresponding convenient device to the survey of mouse blood sugar for the experiment to current experiment development, and it is usually only many people of experimenter mutually support and accomplish the survey of mouse blood sugar, snatch and fix the mouse after, prick mouse tail vein with the blood taking needle and take a blood sample, and often cause the stress response nature blood sugar situation that the mouse rose at this in-process easily, and blood sampling efficiency is comparatively low moreover.
Disclosure of Invention
The invention aims to provide a device for measuring blood sugar by taking blood from tail veins of an experimental mouse, which solves the problem of low blood taking efficiency in the traditional blood taking mode, can effectively relieve the stress reaction of the mouse and improves the preparation rate of blood sugar measurement.
The technical scheme includes that the device for measuring the blood sugar by taking blood from the tail vein of the experimental mouse comprises a bottom plate, baffle plates are arranged on the periphery of the bottom plate, a mouse positioning box is arranged on the bottom plate, a detachable box cover is arranged at the top of the mouse positioning box, a plurality of mouse tail extending holes are formed in one side of the bottom of the mouse positioning box, and a blood taking mechanism is further arranged on the bottom plate.
The present invention is also characterized in that,
a layer of iron sheet is laid on the upper surface of the bottom plate, a magnet sheet A is arranged at the bottom of the mouse positioning box, and the mouse positioning box and the bottom plate are adsorbed together by the magnet sheet A;
the bottom of the blood sampling base is provided with a magnet piece B which adsorbs the blood sampling base on the bottom plate.
Mouse locating box and case lid are light-tight ya keli material.
The blood sampling mechanism comprises a blood sampling base, a groove for placing a mouse tail is formed in the upper surface of one end of the blood sampling base, the other end of the blood sampling base is connected with one end of a pressing plate through a rotating shaft, a spring is coaxially sleeved on the rotating shaft, one end of the spring is in contact with the lower surface of the pressing plate, the other end of the spring is in contact with the lower surface of the base, a blood sampling needle positioning sleeve is arranged at the other end of the pressing plate, and the blood sampling needle positioning sleeve is used for placing a blood sampling needle;
a circular needle hole is formed in the center of the blood taking needle positioning sleeve, and the needle tip of the blood taking needle extends out of the circular needle hole; the circular pinhole is positioned right above the groove.
The top of clamp plate is equipped with the gland, and the one end of gland is articulated with the one end of clamp plate, and the other end lock just of gland is at the other end upper surface of clamp plate, and the gland lid can prevent that the blood taking needle from popping out from the blood taking needle position sleeve on the clamp plate.
The upper surface of gland is equipped with handle B, conveniently pulls up the gland.
The invention has the following beneficial effects:
(1) the base plate, the mouse positioning box and the blood sampling mechanism form a detachable structure by utilizing the principle that the magnet and the iron attract each other, the mouse positioning box can move back and forth on the base plate, a mouse is placed in the mouse positioning box and moves along with the mouse positioning box, the tension can be properly relieved, and the stress response of an experimental mouse is reduced to a certain degree;
(2) the invention fills the gap of the blood sampling device special for the experimental mouse in the traditional measuring method, the blood sampling mechanism in the invention adopts a stapler type design, the convenience and the high efficiency of the blood sampling process are increased, meanwhile, the connection of the blood sampling device and the bottom plate improves the separation mode of the original blood sampling device and the bottom plate, the measuring environment is improved to a certain extent, and the measurement is well and orderly.
(3) The blood sampling and blood sugar measurement can be completed by only one operator by adopting the device disclosed by the invention, so that the labor is saved, and the blood sampling efficiency is improved.
Drawings
FIG. 1 is a schematic diagram showing the structure of a blood glucose measuring device for collecting blood from the tail vein of a laboratory mouse according to the present invention;
FIG. 2 is a schematic diagram showing the structure of a mouse positioning box in the device for measuring blood sugar by collecting blood from the tail vein of a laboratory mouse according to the present invention;
FIG. 3 is a schematic structural diagram of a blood sampling mechanism in the blood glucose measuring device for sampling blood from the tail vein of a laboratory mouse according to the present invention.
In the figure, 1, a box cover, 2, a mouse positioning box, 3, a tail extending hole, 4, a blood sampling mechanism, 5, a gland, 6, a blood sampling positioning sleeve, 7, a blood sampling base, 8, a bottom plate, 9, a baffle, 10, handles A, 11, handles B, 12, a groove, 13, a rotating shaft and 14, and a pressing plate.
Detailed Description
The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.
The invention relates to a device for measuring blood sugar by taking blood from tail veins of an experimental mouse, which comprises a bottom plate 8, wherein baffle plates 9 are arranged around the bottom plate 8, a layer of iron sheet is laid on the upper surface of the bottom plate 8, a mouse positioning box 2 is arranged on the bottom plate 8, a detachable box cover 1 is arranged at the top of the mouse positioning box 2, a handle A10 is arranged at the top of the box cover 1, a plurality of mouse tail extension holes 3 are arranged on one side of the bottom of the mouse positioning box 2, and the mouse tail extension holes 3 are arranged at equal intervals;
the bottom of mouse positioning box 2 is equipped with magnet piece A, and magnet piece A adsorbs mouse positioning box 2 and bottom plate 8 together.
Mouse locating box 2 and case lid 1 are light tight ya keli material.
The bottom plate 8 is also provided with a blood sampling mechanism 4, the blood sampling mechanism 4 comprises a blood sampling base 7, the upper surface of one end of the blood sampling base 7 is provided with a groove 12, and the shape of the groove 12 is adapted to the shape of the tail of the mouse; the other end of the blood taking base 7 is connected with one end of a pressing plate 14 through a rotating shaft 13, a spring is coaxially sleeved on the rotating shaft 13, one end of the spring is in contact with the lower surface of the pressing plate 14, the other end of the spring is in contact with the lower surface of the base 7, a blood taking needle positioning sleeve 6 is arranged at the other end of the pressing plate 14, and the blood taking needle positioning sleeve 6 is used for placing a blood taking needle;
a circular needle hole is formed in the center of the blood taking needle positioning sleeve 6, and the needle tip of the blood taking needle extends out of the circular needle hole, so that blood taking is facilitated; the circular pinhole is positioned right above the groove 12.
A gland 5 is arranged above the pressing plate 14, one end of the gland 5 is hinged with one end of the pressing plate 14, the other end of the gland 5 is just buckled on the upper surface of the other end of the pressing plate 14, and the gland 5 is covered on the pressing plate 14 to prevent the blood taking needle from being ejected out of the blood taking needle positioning sleeve 6;
the upper surface of the gland 5 is provided with a handle B11 to facilitate the pulling of the gland 5.
The bottom of the blood sampling base 7 is provided with a magnet piece B, and the magnet piece B absorbs the blood sampling base 7 on the bottom plate 8.
The invention relates to a use method of a device for measuring blood sugar by taking blood from tail veins of an experimental mouse, which comprises the following steps of firstly putting a needle head of a blood taking needle downwards into a blood taking needle positioning sleeve 6 before use, and extending the needle head of the blood taking needle out of a circular needle hole;
when the mouse positioning box is used, padding is laid on the bottom plate 8, an experimental mouse is placed on the bottom plate 8, the box cover 1 is opened, the experimental mouse is placed in the mouse positioning box 2, the mouse tail penetrates out of the mouse tail extending hole 3 in the proper position and is placed on the groove 12, after the mouse positioning box is used, the mouse tail is fixed by the left hand, the blood taking needle is pressed down on the pressing cover 5 by the right hand, the blood taking needle punctures the tip vein of the tail of the experimental mouse, then the blood glucose detector provided with the blood glucose test paper is held by the right hand, and blood glucose measurement can be carried out after blood overflows. If the blood sampling mechanism 4 is used for the first time and the blood sampling is not successful, the left hand can be used for repeatedly squeezing the blood sampling needle to prick the part, so that the blood at the tail of the rat is prompted to overflow and the blood is measured again.
Claims (1)
1. The utility model provides a device of blood glucose is surveyed with blood sampling of mouse tail vein which characterized in that: the mouse positioning box comprises a bottom plate, wherein baffle plates are arranged on the periphery of the bottom plate, a mouse positioning box is arranged on the bottom plate, a detachable box cover is arranged at the top of the mouse positioning box, a plurality of mouse tail extending holes are formed in one side of the bottom of the mouse positioning box, and a blood sampling mechanism is further arranged on the bottom plate;
the upper surface of the bottom plate is paved with a layer of iron sheet, the bottom of the mouse positioning box is provided with a magnet sheet A, and the mouse positioning box and the bottom plate are adsorbed together by the magnet sheet A;
the bottom of the blood sampling base is provided with a magnet piece B, and the magnet piece B adsorbs the blood sampling base on the bottom plate;
the blood sampling mechanism comprises a blood sampling base, a groove for placing a mouse tail is formed in the upper surface of one end of the blood sampling base, the other end of the blood sampling base is connected with one end of a pressing plate through a rotating shaft, a spring is coaxially sleeved on the rotating shaft, one end of the spring is in contact with the lower surface of the pressing plate, the other end of the spring is in contact with the lower surface of the base, a blood sampling needle positioning sleeve is arranged at the other end of the pressing plate, and the blood sampling needle positioning sleeve is used for placing a blood sampling needle;
a circular needle hole is formed in the center of the blood taking needle positioning sleeve, and the needle tip of the blood taking needle extends out of the circular needle hole; the circular pinhole is positioned right above the groove;
a gland is arranged above the pressing plate, one end of the gland is hinged with one end of the pressing plate, the other end of the gland is just buckled on the upper surface of the other end of the pressing plate, and the gland covers the pressing plate to prevent the blood taking needle from popping out of the blood taking needle positioning sleeve;
the upper surface of the gland is provided with a handle B, so that the gland can be conveniently pulled up;
the mouse positioning box and the box cover are both made of light-proof acrylic materials;
a method for using a device for measuring blood sugar by taking blood from tail veins of an experimental mouse comprises the steps of putting a blood taking needle head downwards into a blood taking needle positioning sleeve before use, wherein the blood taking needle head extends out of a circular needle hole;
when the blood sampling device is used, padding is laid on the bottom plate, an experimental mouse is placed on the bottom plate, the box cover is opened, the experimental mouse is placed in the mouse positioning box, the mouse tail penetrates out of the mouse tail extending hole in the proper position and is placed on the groove, after the mouse tail is placed on the groove, the mouse tail is fixed by the left hand, the right hand presses the pressing cover to press the blood sampling needle downwards, the blood sampling needle punctures the tail tip vein of the experimental mouse, then the blood glucose detector provided with the blood glucose test paper is held by the right hand, blood glucose measurement can be carried out after blood overflows, if the blood sampling mechanism is used for the first time for sampling blood, the left hand can repeatedly squeeze the blood sampling needle to puncture the position, the blood of the mouse tail is enabled to overflow, and blood is measured again.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910866130.6A CN110721002B (en) | 2019-09-09 | 2019-09-09 | Device of blood glucose is surveyed with blood sampling of mouse tail vein for experiments |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910866130.6A CN110721002B (en) | 2019-09-09 | 2019-09-09 | Device of blood glucose is surveyed with blood sampling of mouse tail vein for experiments |
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| CN110721002A CN110721002A (en) | 2020-01-24 |
| CN110721002B true CN110721002B (en) | 2021-09-14 |
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| CN112690786A (en) * | 2020-12-28 | 2021-04-23 | 复旦大学附属中山医院 | Sugar tolerance test system and method thereof |
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| CN110151195A (en) * | 2018-04-13 | 2019-08-23 | 刘奉伟 | A kind of clinical examination blood collection auxiliary device |
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| US20080168951A1 (en) * | 2007-01-11 | 2008-07-17 | Starr Life Sciences Corp. | Small animal restraining device with physiologic sensor mount |
| FR2917628B1 (en) * | 2007-06-19 | 2009-09-18 | Commissariat Energie Atomique | FLUIDIC CONNECTION DEVICE, SYSTEM AND METHOD FOR CONTINUOUSLY SAMPLING FLUID MICROECHANTILLES USING THE DEVICE. |
| CN109938747A (en) * | 2019-03-29 | 2019-06-28 | 西安医学院 | A kind of full-automatic venous blood collection machine |
| CN110141395B (en) * | 2019-06-11 | 2023-11-28 | 中国医科大学附属盛京医院 | Auxiliary device for intravenous injection of rat tail |
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| US4396023A (en) * | 1981-09-21 | 1983-08-02 | Anderson Porter W | Apparatus for obtaining blood samples from animals such as mice or rats |
| CN202637184U (en) * | 2012-07-26 | 2013-01-02 | 黑河学院 | Device for vein haemospasia and fixation of rat |
| CN204446167U (en) * | 2015-01-14 | 2015-07-08 | 苏州大学 | Mouse tail vein injection experimental provision |
| CN205198188U (en) * | 2015-11-12 | 2016-05-04 | 中国农业科学院农业质量标准与检测技术研究所 | Rattail vein experimental apparatus |
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