CN110140848A - A kind of production method of clear haze moistening lung effervescent tablet - Google Patents
A kind of production method of clear haze moistening lung effervescent tablet Download PDFInfo
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- CN110140848A CN110140848A CN201910313568.1A CN201910313568A CN110140848A CN 110140848 A CN110140848 A CN 110140848A CN 201910313568 A CN201910313568 A CN 201910313568A CN 110140848 A CN110140848 A CN 110140848A
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- effervescent tablet
- powder
- moistening lung
- extract
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- 239000007938 effervescent tablet Substances 0.000 title claims abstract description 64
- 210000004072 lung Anatomy 0.000 title claims abstract description 35
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 18
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 30
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 24
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract description 20
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 claims abstract description 16
- 241000287420 Pyrus x nivalis Species 0.000 claims abstract description 15
- 241001506047 Tremella Species 0.000 claims abstract description 14
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000011780 sodium chloride Substances 0.000 claims abstract description 12
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims abstract description 11
- 239000004383 Steviol glycoside Substances 0.000 claims abstract description 11
- 239000008101 lactose Substances 0.000 claims abstract description 11
- 235000019411 steviol glycoside Nutrition 0.000 claims abstract description 11
- 229930182488 steviol glycoside Natural products 0.000 claims abstract description 11
- 150000008144 steviol glycosides Chemical class 0.000 claims abstract description 11
- 235000019202 steviosides Nutrition 0.000 claims abstract description 11
- 229960003511 macrogol Drugs 0.000 claims abstract description 10
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims abstract description 10
- 235000017557 sodium bicarbonate Nutrition 0.000 claims abstract description 10
- 239000002994 raw material Substances 0.000 claims abstract description 9
- 241000234435 Lilium Species 0.000 claims abstract description 8
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 4
- 239000003765 sweetening agent Substances 0.000 claims abstract description 4
- 239000000945 filler Substances 0.000 claims abstract description 3
- 239000003906 humectant Substances 0.000 claims abstract description 3
- 239000000314 lubricant Substances 0.000 claims abstract description 3
- 241001409321 Siraitia grosvenorii Species 0.000 claims abstract 3
- 239000000843 powder Substances 0.000 claims description 62
- 239000000654 additive Substances 0.000 claims description 29
- 230000000996 additive effect Effects 0.000 claims description 28
- 238000002360 preparation method Methods 0.000 claims description 12
- 238000001035 drying Methods 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 10
- 239000002253 acid Substances 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 8
- 239000011812 mixed powder Substances 0.000 claims description 7
- 239000003513 alkali Substances 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 3
- 244000185386 Thladiantha grosvenorii Species 0.000 description 13
- 239000003205 fragrance Substances 0.000 description 10
- 238000012360 testing method Methods 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 239000003826 tablet Substances 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 5
- 235000013361 beverage Nutrition 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 4
- 238000009098 adjuvant therapy Methods 0.000 description 3
- 238000005352 clarification Methods 0.000 description 3
- 229910003460 diamond Inorganic materials 0.000 description 3
- 239000010432 diamond Substances 0.000 description 3
- 210000000697 sensory organ Anatomy 0.000 description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 230000035622 drinking Effects 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 241000205585 Aquilegia canadensis Species 0.000 description 1
- 235000007877 Diospyros australis Nutrition 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 240000002577 Prunus nigra Species 0.000 description 1
- 235000010875 Prunus nigra Nutrition 0.000 description 1
- 240000000851 Vaccinium corymbosum Species 0.000 description 1
- 235000003095 Vaccinium corymbosum Nutrition 0.000 description 1
- 235000017537 Vaccinium myrtillus Nutrition 0.000 description 1
- 235000018288 Vitex doniana Nutrition 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000021014 blueberries Nutrition 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 235000020717 hawthorn extract Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/40—Effervescence-generating compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of production methods of clear haze moistening lung effervescent tablet, the present invention is using Siraitia grosvenorii, pyrus nivalis, tremella, lily as raw material, add disintegrating agent (citric acid, sodium bicarbonate), filler lactose, sweetener steviol glycoside, lubricant Macrogol 6000, draw humectant sodium chloride, through scientific allocation, clear haze moistening lung effervescent tablet is made.Use method of the invention clear haze moistening lung effervescent tablet products directly obtained to be faint yellow, after being dissolved in water, water quality clear, uniformity, cool taste is sour-sweet, has Siraitia grosvenorii, the peat-reeks such as pyrus nivalis.
Description
[technical field]
The present invention relates to a kind of preparation methods of clear haze moistening lung effervescent tablet, belong to the technical field of health-care solid beverage.
[background technique]
Siraitia grosvenorii, integration of drinking and medicinal herbs is sweet in flavor cool in nature, return lung, can be with moistening lung to arrest cough, the hot dryness of the lung of clearing lung-heat.Tremella, it is sweet natured,
Enter lung, has the effects that moistening lung, clearing lung-heat are hot.Pyrus nivalis is cold in nature sweet in flavor, contains multivitamin, has moistening lung clear dry, relieving cough and reducing sputum
Effect.The sweet natured hardship of lily, master enter the lung heart, and containing various nutrients and alkaloid, integration of drinking and medicinal herbs can be dry with clearing lung-heat.Effervesce
Piece is to generate bulk gas after a kind of chance water and the tablet that is disintegrated rapidly.It has be disintegrated it is rapid, convenient, easy to carry,
The advantages that cold water can brew, thus be easy to by big well-established.In recent years, effervescent tablet is gradually expanded to food processing field,
Due to its many merits, so that product sales volume increases, wide market.Domestic at present is mostly fruity effervescent tablet preparation process's
Research or the development of novel taste, such as blueberry effervescent tablet, haw thorn extract effervescent tablet, black plum effervescent tablet, honeysuckle effervescence beverage-flake
Deng however, effervescent tablet is at present almost without the research about anti-haze clearing lung-heat effect.Therefore, the present invention mainly develops one kind and has
The functional form effervescent beverage(s) flake products of anti-haze clearing lung-heat effect.
Product cool taste that the present invention develops, fragrance are agreeable to the taste, and quickly, transparent clarification presents faint yellow for disintegration, have
The distinctive fragrance such as Siraitia grosvenorii.Product tissue morphology is diamond shape, and surface is smooth, and shape is neat, and color is faint yellow, disintegration time
It is short, there is the distinctive fragrance such as Siraitia grosvenorii, mouthfeel is soft, has the function of adjuvant treatment.
[summary of the invention]
Under the premise of guaranteeing taste and effect, the optimum formula of clear haze moistening lung effervescent tablet is developed,
To the lung of haze harm, play the role of adjuvant treatment.
Method provided by the invention be determined using Mixture Experiments Siraitia grosvenorii, tremella, lily, snow pear extract powder it is best
Mouthfeel ratio determines best soda acid source ratio using experiment of single factor, finally adds lactose, steviol glycoside again, and sodium chloride utilizes
Mixture Experiments determine the optimal proportion of all the components, tabletting after all the components mixing, obtained effervescent tablet cool taste, surface light
It is sliding, there is the distinctive fragrance such as Siraitia grosvenorii, and have good healthcare function.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of production method of clear haze moistening lung effervescent tablet comprising the steps of:
(1) mixing preparation of clear haze moistening lung extract: Fructus Monordicae extract powder, snow pear extract powder, dried tremella extract powder
It is mixed in the ratio of 15-30% (w/w), 25-40% (w/w), 10-20% (w/w) and 20-35% (w/w) with Bulbus Lilii extract powder
It closes, is put into blender and 1-3min is sufficiently stirred to get uniform extract mixed powder；
(2) citric acid (acid source) 20-40% the preparation of effervescent tablet powder: is added in the extract mixed powder in step (1)
(w/w), sodium bicarbonate (alkali source) 15-30% (w/w), steviol glycoside (sweetener) 2-6% (w/w), lactose (filler) 20-
30% (w/w), Macrogol 6000 (lubricant) 2-6% (w/w) and sodium chloride (drawing humectant) 0.5-3% (w/w), and sufficiently
1-3min is stirred to get effervescent tablet powder；
(3) drying of effervescent tablet powder: the powder in step (2) is put into electric drying oven with forced convection, and 40-60 DEG C of constant temperature dry
After dry 1-3h, 120 meshes are crossed to get dry effervescent tablet powder；
(4) production of effervescent tablet: the dried powder in step (3) is put into after stirring 1min in blender, is immediately placed in
Tabletting is carried out in tablet press machine, controlled at 10-30 DEG C, humidity is 30% hereinafter, up to effervescent tablet.
In the present invention, it is preferred to, the raw material extract of Siraitia grosvenorii, pyrus nivalis, tremella, lily in the step (1)
Powder is mixed in the ratio of 25% (w/w), 32% (w/w), 14% (w/w), 29% (w/w).
In the present invention, it is preferred to, clear haze moistening lung extract additive amount described in the step (2) is 15% (w/w),
Citric acid additive amount is 30% (w/w), and sodium bicarbonate additive amount is 22% (w/w), and steviol glycoside additive amount is 4% (w/w), cream
Sugared additive amount is 24% (w/w), and Macrogol 6000 additive amount is 4% (w/w) and sodium chloride additive amount is 1% (w/w).
In the present invention, it is preferred to, 120 mesh are crossed after dry 2h under the conditions of 50 DEG C of constant temperature described in the step (3)
Sieve.
In the present invention, it is preferred to, controlled at 20 DEG C described in the step (4).
The beneficial effects of the present invention are:
1) effervescent tablet with clear haze moistening lung can be directly made in production method through the invention, and the effervescent tablet is solid
Body beverage mouthfeel is refrigerant, fragrance is agreeable to the taste, and quickly, transparent clarification, presentation is faint yellow for disintegration, has the distinctive fragrance such as Siraitia grosvenorii.
Product tissue morphology is diamond shape, and surface is smooth, and shape is neat；Single 0.70 ± 0.05g of tablet quality, color are faint yellow, disintegration
Time≤3min has distinctive fragrance, the mouthfeels such as Siraitia grosvenorii soft.
2) present invention not only can satisfy demand of the consumer to beverage, but also can play to pulmonary disease caused by haze sky
The purpose of adjuvant treatment.
3) present invention has many advantages, such as that being disintegrated rapid, convenient, easy to carry, cold water can brew, thus be easy to by
It is big well-established.In recent years, effervescent tablet is gradually expanded to food processing field, due to its many merits, so that product sales volume increases
Add, wide market.
Specific embodiment
The specific embodiment of the invention is described in detail below, advantage and feature will be with description and more clear
Chu.But examples are merely exemplary, and it is not intended to limit the scope of the present invention in any way.Those skilled in the art should understand that
, without departing from the spirit and scope of the invention can details to technical solution of the present invention and form modify or replace
It changes, but these modifications and replacement are fallen within the protection scope of the present invention.
Embodiment 1
A kind of production method of clear haze moistening lung solid effervescent piece, comprising the following steps:
(1) mixing preparation of clear haze moistening lung extract: Fructus Monordicae extract powder, snow pear extract powder, dried tremella extract powder
With Bulbus Lilii extract powder in the ratio mixing in 25% (w/w), 32% (w/w), 14% (w/w), 29% (w/w), it is put into stirring
1-3min is sufficiently stirred to get uniform extract mixed powder in machine；
(2) preparation of effervescent tablet powder: clear haze moistening lung extract additive amount is 15% (w/w), citric acid addition in step (1)
Amount is 30% (w/w), and sodium bicarbonate additive amount is 22% (w/w), and steviol glycoside additive amount is 4% (w/w), and Inclusion of Lactose is
24% (w/w), Macrogol 6000 additive amount is 4% (w/w) and sodium chloride additive amount is 1% (w/w), and 1- is sufficiently stirred
3min is to get effervescent tablet powder；
(3) drying of effervescent tablet powder: the effervescent tablet powder in step (2) is put into electric drying oven with forced convection, constant temperature 50
After DEG C dry 2h, 120 meshes are crossed to get dry effervescent tablet powder；
(4) production of effervescent tablet: the dried powder in step (3) is put into after stirring 1min in blender, is immediately placed in
Tabletting is carried out in tablet press machine, controlled at 20 DEG C, humidity is 30% hereinafter, up to effervescent tablet.
Embodiment 2
A kind of production method of clear haze moistening lung solid effervescent piece, comprising the following steps:
(1) mixing preparation of clear haze moistening lung extract: Fructus Monordicae extract powder, snow pear extract powder, dried tremella extract powder
With Bulbus Lilii extract powder in the ratio mixing in 22% (w/w), 30% (w/w), 18% (w/w), 30% (w/w), it is put into stirring
1-3min is sufficiently stirred to get uniform extract mixed powder in machine；
(2) preparation of effervescent tablet powder: clear haze moistening lung extract additive amount is 15% (w/w), citric acid addition in step (1)
Amount is 30% (w/w), and sodium bicarbonate additive amount is 22% (w/w), and steviol glycoside additive amount is 4% (w/w), and Inclusion of Lactose is
24% (w/w), Macrogol 6000 additive amount is 4% (w/w) and sodium chloride additive amount is 1% (w/w), and 1- is sufficiently stirred
3min is to get effervescent tablet powder；
(3) drying of effervescent tablet powder: the effervescent tablet powder in step (2) is put into electric drying oven with forced convection, constant temperature 50
After DEG C dry 2h, 120 meshes are crossed to get dry effervescent tablet powder；
(4) production of effervescent tablet: the dried powder in step (3) is put into after stirring 1min in blender, is immediately placed in
Tabletting is carried out in tablet press machine, controlled at 20 DEG C, humidity is 30% hereinafter, up to effervescent tablet.
Embodiment 3
A kind of production method of clear haze moistening lung solid effervescent piece, comprising the following steps:
(1) mixing preparation of clear haze moistening lung extract: Fructus Monordicae extract powder, snow pear extract powder, dried tremella extract powder
With Bulbus Lilii extract powder in the ratio mixing in 25% (w/w), 32% (w/w), 14% (w/w), 29% (w/w), it is put into stirring
1-3min is sufficiently stirred to get uniform extract mixed powder in machine；
(2) preparation of effervescent tablet powder: clear haze moistening lung extract additive amount is 15% (w/w), citric acid addition in step (1)
Amount is 30% (w/w), and sodium bicarbonate additive amount is 22% (w/w), and steviol glycoside additive amount is 4% (w/w), and Inclusion of Lactose is
24% (w/w), Macrogol 6000 additive amount is 4% (w/w) and sodium chloride additive amount is 1% (w/w), and 1- is sufficiently stirred
3min is to get effervescent tablet powder；
(3) drying of effervescent tablet powder: the effervescent tablet powder in step (2) is put into electric drying oven with forced convection, constant temperature 60
After DEG C dry 3h, 120 meshes are crossed to get dry effervescent tablet powder；
(4) production of effervescent tablet: the dried powder in step (3) is put into after stirring 1min in blender, is immediately placed in
Tabletting is carried out in tablet press machine, controlled at 20 DEG C, humidity is 30% hereinafter, up to effervescent tablet.
1 four kinds of test example anti-fog haze optimum proportion of materials determine
Fructus Monordicae extract powder, snow pear extract powder, dried tremella extract powder, Bulbus Lilii extract powder are carried out in fact by table proportion
It tests.Every group of experiment is scored according to sense organ evaluating meter, and test result is as shown in table 1.
1 different ratios of raw materials of table is to effervescent tablet qualitative effects
| Siraitia grosvenorii (%) | Pyrus nivalis (%) | Tremella (%) | Lily (%) | Scoring | |
| 1 | 25.691 | 35.000 | 15.475 | 23.834 | 83.7 |
| 2 | 24.116 | 31.445 | 14.440 | 30.000 | 93.3 |
| 3 | 23.906 | 31.848 | 20.000 | 24.246 | 85.0 |
| 4 | 20.000 | 32.860 | 17.140 | 30.000 | 83.0 |
| 5 | 30.000 | 33.486 | 10.000 | 26.514 | 78.3 |
| 6 | 30.000 | 31.014 | 16.144 | 22.842 | 85.3 |
| 7 | 30.000 | 35.000 | 15.000 | 20.000 | 80.0 |
| 8 | 30.000 | 30.000 | 20.000 | 20.000 | 77.0 |
| 9 | 30.000 | 30.000 | 10.000 | 30.000 | 77.7 |
| 10 | 26.395 | 33.605 | 20.000 | 20.000 | 81.0 |
| 11 | 20.000 | 30.000 | 20.000 | 30.000 | 76.0 |
| 12 | 20.000 | 35.000 | 20.000 | 25.000 | 75.3 |
| 13 | 25.000 | 35.000 | 10.000 | 30.000 | 89.0 |
| 14 | 26.727 | 30.000 | 16.826 | 26.447 | 91.0 |
| 15 | 30.000 | 35.000 | 11.941 | 23.059 | 81.7 |
According to Design-Expert software it can be concluded that four kinds of anti-fog haze optimum proportion of materials be Siraitia grosvenorii 24.732%,
Pyrus nivalis 32.327%, tremella 14.142%, lily 28.800%, scoring is 92.6366 under this condition.
The best soda acid of test example 2 is than determining
To test optimum proportioning (Siraitia grosvenorii 24.732%, pyrus nivalis 32.327%, tremella of the raw material powder obtained for the first time
14.142%, lily 28.800%) match to obtain mixed raw material powder, according to basic components steviol glycoside 3%, lactose 27%, sodium chloride
2%, Macrogol 6000 3%, raw material dry powder 25%, soda acid source 40% prepare effervescent tablet, are made with the ratio of alkali source and acid source single
Factorial experiments select sodium bicarbonate and citric acid to prepare effervescent tablet as disintegrating agent, investigate disintegrating agent alkali source (sodium bicarbonate): acid
The ratio in source (citric acid) is respectively the influence of 1:1.2,1:1.25,1:1.3,1:1.35,1:1.4 to effervescent tablet.Test result
As shown in table 2.
2 disintegrating agent ratio of table is to effervescent tablet qualitative effects
As can be seen from the table, when disintegrating agent ratio is 1:1.35, (the 4th group of experiment) disintegration time limited is most short and gas release
Abundant, effervescent tablet sense organ is best.
The determination of 3 effervescent tablet optimum formula of test example
The mixed raw material powder of different ratio, soda acid source, steviol glycoside, lactose, sodium chloride, Macrogol 6000 are pressed into such as table
Shown in match and tested, scored according to sense organ evaluating meter, test result is as shown in table 3.
The different additives of table 3 are with comparison effervescent tablet qualitative effects
According to Design-expert software synthesis disintegration time limited and scoring it can be concluded that optimal adding ingredient matches are as follows:
Mixed raw material powder 15.000%, sweetener 4.000%, lactose 24.000%, sodium chloride 1.000%, gathers at soda acid source 52.000%
Ethylene glycol 6,000 4.000%, disintegration time limited under this condition is 138s, and scoring is 86.3063.
4 product quality analysis of test example
(1) organoleptic indicator: the solid beverage cool taste, fragrance are agreeable to the taste, and quickly, transparent clarification is presented for disintegration
It is faint yellow, there is the distinctive fragrance such as Siraitia grosvenorii.
(2) physical and chemical index: product tissue morphology is diamond shape, and surface is smooth, and shape is neat；Single tablet quality 0.70 ±
0.05g, color are faint yellow.
(3) product evaluation: disintegration time≤3min has distinctive fragrance, the mouthfeels such as Siraitia grosvenorii soft.
Claims (5)
1. a kind of production method of clear haze moistening lung effervescent tablet, it is characterised in that the following steps are included:
(1) mixing preparation of clear haze moistening lung extract: Fructus Monordicae extract powder, snow pear extract powder, dried tremella extract powder and hundred
It closes extract powder to mix in the ratio of 15-30% (w/w), 25-40% (w/w), 10-20% (w/w) and 20-35% (w/w), put
Enter blender and 1-3min is sufficiently stirred to get uniform extract mixed powder；
(2) citric acid (acid source) 20-40% (w/ the preparation of effervescent tablet powder: is added in the extract mixed powder in step (1)
W), sodium bicarbonate (alkali source) 15-30% (w/w), steviol glycoside (sweetener) 2-6% (w/w), lactose (filler) 20-30%
(w/w), Macrogol 6000 (lubricant) 2-6% (w/w) and sodium chloride (drawing humectant) 0.5-3% (w/w), and 1- is sufficiently stirred
3min is to get effervescent tablet powder；
(3) drying of effervescent tablet powder: the powder in step (2) is put into electric drying oven with forced convection, 40-60 DEG C of constant temperature dry 1-
After 3h, 120 meshes are crossed to get dry effervescent tablet powder；
(4) production of effervescent tablet: the dried powder in step (3) is put into after stirring 1min in blender, is immediately placed in tabletting
Tabletting is carried out in machine, controlled at 10-30 DEG C, humidity is 30% hereinafter, up to effervescent tablet.
2. the production method of clear haze moistening lung effervescent tablet according to claim 1, it is characterised in that: described in step (1)
Siraitia grosvenorii, pyrus nivalis, tremella, lily raw material extract powder press 25% (w/w), 32% (w/w), 14% (w/w), 29% (w/
W) ratio mixing.
3. the production method of clear haze moistening lung effervescent tablet according to claim 1, it is characterised in that: described in step (2)
Clear haze moistening lung extract additive amount is 15% (w/w), and citric acid additive amount is 30% (w/w), and sodium bicarbonate additive amount is 22%
(w/w), steviol glycoside additive amount is 4% (w/w), and Inclusion of Lactose is 24% (w/w), and Macrogol 6000 additive amount is 4%
(w/w) and sodium chloride additive amount is 1% (w/w).
4. the production method of clear haze moistening lung effervescent tablet according to claim 1, it is characterised in that: described in step (3)
Under the conditions of 50 DEG C of constant temperature after dry 2h, 120 meshes are crossed.
5. the production method of clear haze moistening lung effervescent tablet according to claim 1, it is characterised in that: described in step (4), control
Temperature processed is 20 DEG C.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111053178A (en) * | 2019-12-26 | 2020-04-24 | 桂林医学院 | Fructus momordicae composite beverage effervescent tablet and preparation method thereof |
| CN111728206A (en) * | 2020-07-20 | 2020-10-02 | 黑龙江仁合堂药业有限责任公司 | Composition for clearing internal heat, beverage for clearing internal heat and preparation method thereof |
-
2019
- 2019-04-18 CN CN201910313568.1A patent/CN110140848A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111053178A (en) * | 2019-12-26 | 2020-04-24 | 桂林医学院 | Fructus momordicae composite beverage effervescent tablet and preparation method thereof |
| CN111728206A (en) * | 2020-07-20 | 2020-10-02 | 黑龙江仁合堂药业有限责任公司 | Composition for clearing internal heat, beverage for clearing internal heat and preparation method thereof |
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Application publication date: 20190820 |