CN110123892A - A kind of draft emulsifiable paste and preparation method thereof for treating anemofrigid cold - Google Patents

A kind of draft emulsifiable paste and preparation method thereof for treating anemofrigid cold Download PDF

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Publication number
CN110123892A
CN110123892A CN201910436485.1A CN201910436485A CN110123892A CN 110123892 A CN110123892 A CN 110123892A CN 201910436485 A CN201910436485 A CN 201910436485A CN 110123892 A CN110123892 A CN 110123892A
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China
Prior art keywords
parts
draft
emulsifiable paste
anemofrigid cold
radix
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Pending
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CN201910436485.1A
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Chinese (zh)
Inventor
刘金权
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Sichuan Jin Huiai Health Management Co Ltd
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Sichuan Jin Huiai Health Management Co Ltd
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Priority to CN201910436485.1A priority Critical patent/CN110123892A/en
Publication of CN110123892A publication Critical patent/CN110123892A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Abstract

The invention discloses a kind of draft emulsifiable pastes and preparation method thereof for treating anemofrigid cold, including following component by weight: 25-32 parts of the root of Dahurain angelica, 7-12 parts of ramulus cinnamomi, 10-15 parts of Rhizoma Et Radix Notopterygii, 9-16 parts of radix saposhnikoviae, 3-10 parts of Radix Paeoniae Alba and 9-13 parts of semen armeniacae amarae.The present invention is formed using draft drug matching, and is targetedly applied with, treating both manifestation and root cause of disease, has good curative effect, effective percentage up to 96%.

Description

A kind of draft emulsifiable paste and preparation method thereof for treating anemofrigid cold
Technical field
The invention belongs to traditional Chinese medicine emulsifiable paste technical fields, and in particular to a kind of draft emulsifiable paste for treating anemofrigid cold and its preparation Method.
Background technique
Anemofrigid cold is the flu because caused by suffering from cold wind, and the autumn and winter occur more.Its symptom be ache all over, stream of having a stuffy nose Tears bring up phlegm when one coughs.Anemofrigid cold, which is that the heresy of chill is outer, attacks, caused by Lung Qi obstraction.Symptom is visible: aversion to cold is heavy, it is light, lossless to generate heat, It is thin white that headache bodily pain, stuffy nose with watery discharge, cough spit dilute white phlegm, not thirsty or thirsty hot drink preference, tongue fur.Therapy should be with relieving the exterior syndrome with drugs pungent in flavor and warm in property It is main.
The drug for the treatment of anemofrigid cold is various at present, and mainly Western medicine and Chinese patent drug, western medicine class are Chemical composition thats, mainly It is treated using antiviral, antipyretic-antalgic and antibiotic, the curative effect that do not eradicate, the state of an illness is easy repeatedly, and there are certain pairs Effect；And Chinese patent drug is then plurality of Chinese to be crushed molding to be made, and Chinese patent drug is a lot of to the effect of prevention, therapeutic effect is not Obviously, and slow curative effect.
It is existing treatment anemofrigid cold drug be substantially it is oral, the oral of Western medicine is easy to cause tablet to cover when oral Trunnion causes discomfort to pill taker；Since Chinese patent drug is mostly that traditional Chinese medicine forms, Chinese patent drug is mostly bitter, to cause Majority do not like.
Summary of the invention
The technical problems to be solved by the invention are in view of the above shortcomings of the prior art, to provide and a kind of treat chill sense Draft emulsifiable paste emitted and preparation method thereof, the draft emulsifiable paste are formulated using pure Chinese medicine, traditional oral medication are changed to Application treatment avoids oral drugs to discomfort caused by pill taker, while using Chinese medicine application, and quick, good effect can reach To the purpose of radical cure.
The technical scheme adopted by the invention is that: a kind of draft emulsifiable paste that treating anemofrigid cold, including by weight Following component: 25-32 parts of the root of Dahurain angelica, 7-12 parts of ramulus cinnamomi, 10-15 parts of Rhizoma Et Radix Notopterygii, 9-16 parts of radix saposhnikoviae, 3-10 parts of Radix Paeoniae Alba and semen armeniacae amarae 9-13 Part.
Preferably, the anemofrigid cold draft emulsifiable paste includes 10 parts of 30 parts of the root of Dahurain angelica, ramulus cinnamomi by weight, Rhizoma Et Radix Notopterygii 10 Part, 10 parts of radix saposhnikoviae, 10 parts of Radix Paeoniae Alba and 10 parts of semen armeniacae amarae.
A kind of preparation method of draft emulsifiable paste that treating anemofrigid cold, comprising the following steps:
(1) root of Dahurain angelica, ramulus cinnamomi, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, Radix Paeoniae Alba and semen armeniacae amarae are chosen according to the ratio；
(2) raw material of selection is crushed, crush temperature be 0-10 DEG C, grinding time 25-30min, it is smashed Hybrid particles mesh number is 280-320 mesh；
(3) smashed hybrid particles are emulsified, emulsifying temperature control is at 60-75 DEG C, emulsification times 30- 60min treats the draft emulsifiable paste of anemofrigid cold after emulsification.
Preferably, the speed of agitator in step (3) in emulsion process is controlled in 40-60r/min.
The root of Dahurain angelica: property is acrid in flavour and warm in nature；Enter lung, spleen, stomach meridian；For wind-dispelling, eliminating dampness is reduced swelling, analgesic.Control headache, pain in the supra-orbital bone, tooth Bitterly, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, scabies；
Ramulus cinnamomi: it is pungent, it is sweet, it is warm-natured, return bladder meridian, the heart channel of Hang-Shaoyin, lung channel；Sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, helps yang transforming qi, cold dispelling stop Bitterly；Main exterior syndrome due to wind-cold；Numbness and ache of cold dampness；Peripheral coldness；Amenorrhea and algomenorrhea；Abdominal mass caking, thoracic obstruction, palpitaition, phlegm retention, difficult urination are used In anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, arthralgia, phlegm retention, oedema, palpitaition, renal mass；
Rhizoma Et Radix Notopterygii: property is pungent, tepor, and bitter, dry scattered property is big, and diverging inducing diaphoresis power is strong, directly upper mountain peak top, tonneau the five internal organs, row limb arm, With except the part of the body cavity above the diaphragm housing the heart and lungs head term shoulder back pain imitate it is good；Wind-damp dispelling analgesic, inducing sweat and dispelling exogenous evils, with controlling arthralgia due to wind-cold-dampness disease and the wet exterior syndrome of affection of exogenous wind-cold；
Radix saposhnikoviae: it is acrid flavour, sweet, it is warm-natured；Have the effect of sweating, eliminating the phlegm, wind dispelling, deliver, ease pain, cure mainly anemofrigid cold, headache, Fever, joint pain, tetanus；
Radix Paeoniae Alba: bitter, acid, it is slightly cold, enter liver, the spleen channel, enriches blood and hold back yin, soft liver analgesic, yin-nourishing calming the liver.Hardship is cool to expel the heat-evil, and has benefit Blood holds back yin, soft liver relieves pain, the function of calming the liver, treats all pains；
Semen armeniacae amarae: main cough with dyspnea is thunderous, sore throat, lower gas, galactopoiesis metal-inflicted wound, bitterly disappointed renal mass；For cough and asthma, fullness sensation in chest phlegm More, deficiency of blood saliva is withered, dry constipation of intestines.
The beneficial effects of the present invention are:
(1) it is used to be applied with by the way that emulsifiable paste is made in draft Chinese medicine, eliminates the inconvenience of patient's medication, and first cross is avoided to imitate It answers and the peak valley phenomenon of oral medicine and half-life period influences；
(2) it is directed to anemofrigid cold, emulsifiable paste is applied at corresponding acupuncture point, emulsifiable paste pharmacological property enters acupuncture point relevant to anemofrigid cold In, it is targetedly applied with, so that emulsifiable paste is quick, good effect, there is no any side effects, can be applied with for a long time.
The present invention is formed using draft drug matching, and is targetedly applied with, treating both manifestation and root cause of disease, has good treatment Effect, effective percentage up to 96%.
Specific embodiment
Below in conjunction with specific embodiment, invention is further described in detail.
Embodiment 1
The draft emulsifiable paste for the treatment of anemofrigid cold provided in this embodiment, is prepared by following steps:
(1) 30 parts of the root of Dahurain angelica, 10 parts of ramulus cinnamomi, 10 parts of Rhizoma Et Radix Notopterygii, 10 parts of radix saposhnikoviae, 10 parts of Radix Paeoniae Alba and semen armeniacae amarae 10 are chosen by weight Part；
(2) raw material of selection is crushed, crush temperature be 8 DEG C, grinding time 28min, smashed mixing Grain mesh number is 280 mesh；
(3) smashed hybrid particles are sent into emulsifying homogeneous machine and are emulsified, emulsifying temperature controls the emulsification at 60 DEG C Time is 45min, and the speed of agitator of emulsifying homogeneous machine controls after 45r/min, emulsification up to treatment chill sense in emulsion process The draft emulsifiable paste emitted.
Embodiment 2
The draft emulsifiable paste for the treatment of anemofrigid cold provided in this embodiment, is prepared by following steps:
(1) 28 parts of the root of Dahurain angelica, 9 parts of ramulus cinnamomi, 12 parts of Rhizoma Et Radix Notopterygii, 14 parts of radix saposhnikoviae, 8 parts of Radix Paeoniae Alba and semen armeniacae amarae 12 are chosen by weight Part；
(2) raw material of selection is crushed, crush temperature be 10 DEG C, grinding time 25min, smashed mixing Grain mesh number is 300 mesh；
(3) smashed hybrid particles are sent into emulsifying homogeneous machine and are emulsified, emulsifying temperature controls the emulsification at 70 DEG C Time is 30min, and the speed of agitator of emulsifying homogeneous machine controls after 60r/min, emulsification up to treatment chill sense in emulsion process The draft emulsifiable paste emitted.
Embodiment 3
The draft emulsifiable paste for the treatment of anemofrigid cold provided in this embodiment, is prepared by following steps:
(1) 31 parts of the root of Dahurain angelica, 12 parts of ramulus cinnamomi, 15 parts of Rhizoma Et Radix Notopterygii, 12 parts of radix saposhnikoviae, 4 parts of Radix Paeoniae Alba and semen armeniacae amarae 10 are chosen by weight Part；
(2) raw material of selection is crushed, crush temperature be 3 DEG C, grinding time 30min, smashed mixing Grain mesh number is 285 mesh；
(3) smashed hybrid particles are sent into emulsifying homogeneous machine and are emulsified, emulsifying temperature controls the emulsification at 65 DEG C Time is 55min, and the speed of agitator of emulsifying homogeneous machine controls after 40r/min, emulsification up to treatment chill sense in emulsion process The draft emulsifiable paste emitted.
The draft emulsifiable paste of present invention treatment anemofrigid cold is externally applied to Dazhui acupoint and Tiantu cave by application method of the invention, Each external application early, middle and late daily is primary, and 3 as a treatment course.
Clinical trial:
(1) clinical data
It is selected in more than 200 example of anemofrigid cold patient altogether and carries out clinical observation, male 95, female 110, the age was at 20-60 years old Between.
(2) diagnostic criteria
The fever mainly shown according to patient is light, it is lossless, feel cold, bodily pain of having a headache, stuffy nose with watery discharge, cough spit it is dilute white Phlegm, not thirsty or thirsty hot drink preference, tongue fur Bao Bailai judgement；
(3) the draft emulsifiable paste of present invention treatment anemofrigid cold is externally applied to Dazhui acupoint and Tiantu cave by treatment method, early daily, In, evening it is each be applied with primary, 3 are as a treatment course, need two courses for the treatment of, first course for the treatment of is treatment stage, and second stage is Consolidation phase.
(4) efficacy assessment standard
Recovery from illness: the pains such as headache, abscess of throat, Muscular stiffness disappear；Generate heat it is light, lossless, feel cold, the diseases such as stuffy nose with watery discharge Shape disappears；
Effective: the symptoms such as headache, abscess of throat, Muscular stiffness are mitigated alleviation；With generate heat it is light, lossless, feel cold and The symptoms such as stuffy nose with watery discharge；
Improve: the symptoms such as headache, abscess of throat, Muscular stiffness are mitigated；With feel cold, the symptoms such as stuffy nose with watery discharge；
Invalid: the symptoms such as headache, abscess of throat, Muscular stiffness still continue；With feel cold, be lossless, stuffy nose with watery discharge etc. Symptom.
(5) treatment results
More than 200 example patients are treated and the later period tracks, improvement rate 100%, obvious effective rate 98.62%, cure rate 93.33%, therapeutic effect is significant.
The above is only the preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, any The transformation and replacement carried out based on technical solution provided by the present invention and inventive concept should all be covered in protection model of the invention In enclosing.

Claims (4)

1. a kind of draft emulsifiable paste for treating anemofrigid cold, it is characterised in that: including following component by weight: root of Dahurain angelica 25- 32 parts, 7-12 parts of ramulus cinnamomi, 10-15 parts of Rhizoma Et Radix Notopterygii, 9-16 parts of radix saposhnikoviae, 3-10 parts of Radix Paeoniae Alba and 9-13 parts of semen armeniacae amarae.
2. a kind of draft emulsifiable paste for treating anemofrigid cold according to claim 1, it is characterised in that: including by weight 30 parts of the root of Dahurain angelica, 10 parts of ramulus cinnamomi, 10 parts of Rhizoma Et Radix Notopterygii, 10 parts of radix saposhnikoviae, 10 parts of Radix Paeoniae Alba and 10 parts of semen armeniacae amarae.
3. a kind of preparation method of draft emulsifiable paste for treating anemofrigid cold according to claim 1, it is characterised in that: including Following steps:
(1) root of Dahurain angelica, ramulus cinnamomi, Rhizoma Et Radix Notopterygii, radix saposhnikoviae, Radix Paeoniae Alba and semen armeniacae amarae are chosen according to the ratio；
(2) raw material of selection is crushed, crush temperature be 0-10 DEG C, grinding time 25-30min, smashed mixing Particle mesh number is 280-320 mesh；
(3) smashed hybrid particles are emulsified, emulsifying temperature is controlled at 60-75 DEG C, emulsification times 30-60min, cream The draft emulsifiable paste of anemofrigid cold is treated after change.
4. a kind of preparation method of draft emulsifiable paste for treating anemofrigid cold according to claim 3, it is characterised in that: step (3) speed of agitator in emulsion process is controlled in 40-60r/min.
CN201910436485.1A 2019-05-23 2019-05-23 A kind of draft emulsifiable paste and preparation method thereof for treating anemofrigid cold Pending CN110123892A (en)

Priority Applications (1)

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CN201910436485.1A CN110123892A (en) 2019-05-23 2019-05-23 A kind of draft emulsifiable paste and preparation method thereof for treating anemofrigid cold

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Application Number Priority Date Filing Date Title
CN201910436485.1A CN110123892A (en) 2019-05-23 2019-05-23 A kind of draft emulsifiable paste and preparation method thereof for treating anemofrigid cold

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CN110123892A true CN110123892A (en) 2019-08-16

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Application publication date: 20190816

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