CN110123819B - Medicine and device for treating scars - Google Patents
Medicine and device for treating scars Download PDFInfo
- Publication number
- CN110123819B CN110123819B CN201910478332.3A CN201910478332A CN110123819B CN 110123819 B CN110123819 B CN 110123819B CN 201910478332 A CN201910478332 A CN 201910478332A CN 110123819 B CN110123819 B CN 110123819B
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- scars
- medicine
- treating
- capsule tube
- scar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3415—Trocars; Puncturing needles for introducing tubes or catheters, e.g. gastrostomy tubes, drain catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3468—Trocars; Puncturing needles for implanting or removing devices, e.g. prostheses, implants, seeds, wires
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Abstract
The invention belongs to the technical field of medicine preparation, and discloses a medicine and a device for treating scars. The silicone capsule tube is filled with medicine for treating scar. The anti-inflammatory and anti-inflammatory medicament is prepared from the raw materials of triamcinolone acetonide, diphenhydramine and type A botulinum toxin which are commonly used in clinic, and the medicament is clinically applied for a long time, because the medicament dose is very small, the medicament dose is in scars, and the hard fibrous tissues in the scars are limited and basically dispersed in the scar tissues. The invention implants the scars through the silicone capsule tubes, slowly releases the medicines, the three medicines can change at different periods, after the scars are healed, only the silicone capsule tube containing the mixed solution of diphenhydramine and type A botulinum toxin is buried into the scars and can be taken out after the scars are healed, the softening and healing effects of the scars are achieved, the problems that frequent injection in the scars is performed, the whole cost is high and the whole cost is painful are avoided.
Description
Technical Field
The invention belongs to the technical field of medicine preparation, and particularly relates to a medicine and a device for treating scars.
Background
Scarring is a general concept that is a collective term for the morphological and histopathological changes of the skin tissue that occur after various traumas. It is a normal and inevitable physiological reaction in the natural healing process of wounds or wound surfaces after human body trauma, and is also an inevitable result of the healing process of the wounds. The nature of a scar is an abnormal, incompetent tissue without normal skin tissue structure and physiological function, which loses normal tissue vitality. Scars not only disrupt the body's beauty, but also interfere with the physiological function of the associated tissue or organ, even leading to deformity. At present, there are conservative treatments and surgical treatments for scars. A very effective method for conservative treatment is an injection method in scars, the method has a relatively definite effect and a relatively good effect, and is mainly used for injecting glucocorticoid medicaments such as hydrocortisone and the like, but regular injection in scars, namely frequent injection is needed, the total cost is high and the injection is painful, in order to avoid the problem of injection pain, a syringe without a needle head appears on the market, but the syringe is not popularized and applied clinically, the liquid medicine is dispersed in scars by the pressure of the syringe, but keloids are very thick and hard, the medicaments entering the scars are limited, the exertion of the drug effect is greatly influenced, and the injection method in scars is adopted clinically.
In summary, the problems of the prior art are as follows:
the existing intrascar injection is painful, needs repeated injections and is higher in cost. A pinless syringe appears in the market, but the pinless syringe is not popularized and applied clinically, liquid medicine is dispersed in scars by syringe pressure, but because keloids are very back and hard, the medicine entering the scars is limited, the exertion of the medicine effect is greatly influenced, and meanwhile, the design and the operation of the pinless syringe also have great problems.
The difficulty of solving the technical problems is as follows: the greatest difficulty in solving the problems is how to deliver the medicines to the keloid without pain or with little pain, so that the medicines can continuously exert the functions and reach the maximum, and if a device can be innovated to fill with scars and prevent the medicines from being slowly released, the problems of poor efficacies of common direct injections and needleless injectors can be solved, and the difficulties lie in the selection and burying of the extractor.
The significance of solving the technical problems is as follows:
the technology solves the problems of high cost and great pain caused by repeated injections at present, and also solves the defect of poor effect of small dispersion of the medicine in the scar of a syringe without a needle. After the technology is widely applied, the satisfaction degree of a patient can be greatly improved, the aims of less pain, low cost and good effect are achieved, and huge economic and social benefits are brought.
Disclosure of Invention
In view of the problems of the prior art, the present invention provides a medicament and a device for treating scars.
The invention is realized in such a way that the medicine for treating the scar consists of inflammation-removing pine, diphenhydramine and type A botulinum toxin; 1 ml of 0.5 percent of triamcinolone acetonide, 1 ml of 1 percent of diphenhydramine and 3 ml of A type botulinum toxin 4 unit are taken as an injection unit.
Another object of the present invention is to provide a device containing the medicine for treating scars, which is provided with a silicone capsule tube filled with the medicine for treating scars.
Furthermore, both ends of the silicone capsule tube are of round and blunt structures.
Another object of the present invention is to provide a method for delivering a drug for treating scars, which comprises the steps of: the hollow puncture needle comprises a puncture cannula and a needle core; the needle core sends the silicone capsule tube into the puncture cannula, the puncture cannula is pulled out, the needle core pushes the silicone capsule tube to be arranged at the position to be implanted, the needle core is also pulled out after the needle sleeve is pulled out, and the medicine is conveyed.
In summary, the advantages and positive effects of the invention are:
the anti-inflammatory and anti-inflammatory medicament for treating the scars is implanted into the scars through the special trocar by the silicone capsule tube, slowly releases the medicament, takes out the scars after the scars are healed, achieves the effect of softening and healing the scars, and avoids the problems of frequent injection, high cost and pain.
The medicine for treating scars consists of triamcinolone acetonide, diphenhydramine and A-type botulinum toxin, and the device for treating scars is a silicone capsule tube filled with the medicine for treating scars. The antiphlogistic and soothing pine, the diphenhydramine and the A-type botulinum toxin are common clinical medicines, and are clinically good medicines with good treatment effect after long-term clinical application, because the medicine dose is very small, and the medicine is in scars, the medicine is mainly diffused and absorbed in the scars, the whole body absorption is very little, the influence on the whole body is small, and no side effect is generated.
The device for treating the medicament for the scars is provided with the silicon capsule tube, and the silicon capsule tube is filled with the medicament for treating the scars. The other auxiliary tool is a hollow puncture needle, a cylindrical sleeve core is arranged in the middle of the puncture needle, and is used for conveying the silicone capsule tube filled with the medicine into the scar, namely the sleeve is penetrated into the scar for a certain depth and is larger than the length of the silicone capsule tube, the silicone capsule tube is conveyed into the sleeve tube by using the needle core, the needle core pushes against the silicone capsule tube to reach a preset design position, the needle core is also pulled out after the needle sleeve is pulled out, and the medicine conveying process is completed. The technology that the medicines are buried inside scars is not found through searching for the existing medicine scar treatment, and belongs to the initiative of scar treatment. By comparing the medicines each new impoundment within a scar and 30 clinical intralesional injections into each 30 cases, the new impoundment within a scar does not need to be repeatedly operated for the rest of time except that the new impoundment was painful for the new impoundment, the medicines are slowly released within the scar to continuously exert the effect, and the cost is low. The recovery time is about 20 days earlier than the injection method.
Description of the drawings:
FIG. 1 is a schematic diagram of an apparatus for treating scars according to an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a cannula device for delivering a drug according to an embodiment of the present invention;
in the figure: 1. a silicone capsule tube; 2. puncturing a cannula; 3. a needle core.
Fig. 3 and 4 are schematic views illustrating the treatment effect of the medicament for treating scars provided by the embodiment of the invention;
in the figure: (a) before treatment; (b) after treatment.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
As shown in fig. 1, the device for treating scars provided by the embodiment of the invention is provided with a silicon capsule tube 1, and the silicon capsule tube 1 is filled with medicine for treating scars. The two ends of the silicon capsule tube 1 are in a round blunt structure.
The medicine for treating scars provided by the embodiment of the invention consists of hydrocortisone, diphenhydramine and botulinum toxin type A. 1 ml of 0.5 percent of triamcinolone acetonide, 1 ml of 1 percent of diphenhydramine and 4 units of A-type botulinum toxin are mixed, and 3 ml is used as an injection unit.
As shown in figure 2, the hollow puncture needle comprises a puncture cannula 2 and a needle core 3; the needle core 3 sends the silicon capsule tube 1 into the puncture sleeve 2, the puncture sleeve 2 is pulled out, the needle core 3 is arranged at the position to be implanted against the silicon capsule tube 1, the needle core 3 is pulled out after the needle sleeve is pulled out, and the medicine is conveyed. Is a hollow inner needle with a cylinder in the middle and is used for a device for delivering medicine. The hollow puncture needle is provided with a cylindrical needle in the middle and is used for conveying the silicone capsule tube in the scar, namely, the sleeve is penetrated into the scar for a certain depth and is larger than the length of the silicone capsule tube, the silicone capsule tube is conveyed into the sleeve by using the needle core, the puncture sleeve is pulled out, the needle core is arranged at the position to be implanted against the silicone capsule tube, the needle core is also pulled out after the needle sleeve is pulled out, and the medicine conveying process is finished.
The invention fills the medicine for treating the scar in the silicon capsule tube 1, implants the silicon capsule tube 1 into the scar by the trocar 2, slowly releases the medicine, and takes out the scar after the scar is healed, thereby achieving the effect of softening and healing the scar.
The technical effects of the present invention will be described in detail below with reference to the accompanying drawings.
As shown in fig. 3 and 4, the invention selects thicker scars by 30 cases of scar injection for clinical comparison at an outpatient department of a burn and plastic beauty center of a tertiary hospital and buries each new scar internally, and compares the pain, the treatment times, the acceptance of patients, the recovery speed of scars and the like, wherein the pain is heavier in all 30 cases of the injection groups in scars, the pain is more painful in each treatment, the average treatment is 8 +/-1.12 times, and the treatment method is not received in 30 cases, and the recovery time is 60 +/-7.25 days. The inner scars was found to have no pain when the patient was cultivated as a result of anesthesia for the first time, and the treatment was 1 time, 30 cases had received the treatment very relevantly with the scars leveled for 40 ± 5.18 days.
The medicine for treating the scars provided by the embodiment of the invention consists of 1 ml of inflammation-removing pine, 1 ml of diphenhydramine and 4 units of A-type botulinum toxin, wherein the mixture ratio is that 1 ml of 0.5% inflammation-removing pine, 1 ml of 1% diphenhydramine and 4 units of A-type botulinum toxin are mixed, 3 ml is taken as an injection unit, more or less injection units are carried out according to the size of the scars, a device for treating the scars is a silicone capsule tube, and the silicone capsule tube is filled with the medicine for treating the scars. The antiphlogistic and soothing pine, the diphenhydramine and the A-type botulinum toxin are common clinical medicines, and can achieve good clinical treatment effect after being clinically applied for a long time.
The invention provides a device filled with medicine for treating scars. The other auxiliary tool is a hollow puncture needle, a cylindrical needle core is arranged in the middle of the hollow needle and used for conveying the silicon capsule tube in the scar, namely the sleeve penetrates into the scar to a certain depth and is larger than the length of the silicon capsule tube, the silicon capsule tube is conveyed into the sleeve by the needle core, the needle core pushes against the silicon capsule tube to place the medicine at a pre-designed position, and the needle core is also pulled out after the pillowcase is pulled out, so that the medicine conveying process is completed. The two ends of the silicone capsule tube are in a round blunt structure. The trocar is hollow in the middle and is provided with a cylindrical trocar core.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.
Claims (1)
1. A pharmaceutical preparation for treating scars is characterized by comprising a silicon capsule tube and a medicament for treating scars; the medicine for treating scars consists of triamcinolone acetonide, diphenhydramine and type A botulinum toxin; wherein 1 ml of 0.5 percent of triamcinolone acetonide, 1 ml of 1 percent of diphenhydramine and 3 ml of type A botulinum toxin 4 unit are taken as an injection unit;
the medicine is placed in a silicon capsule tube;
the two ends of the silicone capsule tube are of round blunt structures.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910478332.3A CN110123819B (en) | 2019-06-03 | 2019-06-03 | Medicine and device for treating scars |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910478332.3A CN110123819B (en) | 2019-06-03 | 2019-06-03 | Medicine and device for treating scars |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110123819A CN110123819A (en) | 2019-08-16 |
| CN110123819B true CN110123819B (en) | 2022-03-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910478332.3A Active CN110123819B (en) | 2019-06-03 | 2019-06-03 | Medicine and device for treating scars |
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| Country | Link |
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| CN (1) | CN110123819B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720681A (en) * | 2013-12-27 | 2014-04-16 | 柳州市工人医院 | Application of tranilast in preparing medicine for preventing pathological scar |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004293463A1 (en) * | 2003-11-20 | 2005-06-09 | Angiotech International Ag | Implantable sensors and implantable pumps and anti-scarring agents |
| CN100584375C (en) * | 2005-12-16 | 2010-01-27 | 冯时 | Formula for treating scar |
| ES2310142B1 (en) * | 2007-06-15 | 2009-12-04 | Lipotec S.A | PIGMENTATION REGULATING COMPOUNDS. |
| CN102861318B (en) * | 2012-09-29 | 2014-11-26 | 山西医科大学 | Application of A-type kreotoxin heavy chains to exciting regeneration of neurite |
| CN105287441B (en) * | 2015-11-17 | 2016-09-28 | 哈尔滨乾佰纳生物药业有限公司 | A kind of Silica hydrogel scar plaster and preparation method thereof |
| CN206434466U (en) * | 2016-10-21 | 2017-08-25 | 苏州灵岩医疗科技股份有限公司 | Safety-type subdermal implantation puts medicine pin |
| CN208741250U (en) * | 2017-07-12 | 2019-04-16 | 苏州灵岩医疗科技股份有限公司 | Crosspointer cast subdermal implantation sets medicine needle |
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- 2019-06-03 CN CN201910478332.3A patent/CN110123819B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720681A (en) * | 2013-12-27 | 2014-04-16 | 柳州市工人医院 | Application of tranilast in preparing medicine for preventing pathological scar |
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| Publication number | Publication date |
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| CN110123819A (en) | 2019-08-16 |
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