CN1101208C - Medicine for treating uninary calculaus and its preparing process - Google Patents
Medicine for treating uninary calculaus and its preparing process Download PDFInfo
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- CN1101208C CN1101208C CN 00124371 CN00124371A CN1101208C CN 1101208 C CN1101208 C CN 1101208C CN 00124371 CN00124371 CN 00124371 CN 00124371 A CN00124371 A CN 00124371A CN 1101208 C CN1101208 C CN 1101208C
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- medicine
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- lithangiuria
- polyporus
- potassium chloride
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Abstract
The present invention discloses medicine for treating urinary calculus. The medicine uses tickclover herbs from Sichuan of China, perfoliate knotweed herbs, folium pyrrosiae, armstrong, water plantain, caulis, polyporus, cogongrass rhizomes, radix curcumae from Sichuan of China, tuckahoes, talcum powder and potassium chloride which are prepared into pills, tablets, capsules, etc. The effective rate for treating urinary calculus reaches 91.7%.
Description
The present invention relates to be used for the treatment of the pharmaceutical composition of lithangiuria, specifically is the Chinese patent medicine of feedstock production with Chinese herbal medicine.
Betiding the calculus general designation lithangiuria of kidney, ureter, bladder, is commonly encountered diseases, frequently-occurring disease clinically.Modern medicine mainly contains two kinds to effective treatment means of lithangiuria: surgical removal and ultrasound wave rubble.These two kinds of Therapeutic Method are reliable for effect, but certain indication restriction is all arranged, and are more suitable to calculus single-shot, that volume is bigger, and the calculus of the many places of occurring together just is difficult to carry out.These two kinds of Therapeutic Method also cause certain damage to human body in implementation process, therefore except that the basic body constitution to the patient has the requirement of selection, also have the worry that multiple complications, sequela take place.Moreover therefore the economic cost of these two kinds of Therapeutic Method has usually limited many patients' that are in a bed economic state treatment also than higher.
About the treatment of lithangiuria, except that above-mentioned operation and hyperacoustic method, patent documentation and non-patent literature were also reported some " fossils " " the drive stone " drug treatment of " calculus ".These Chinese and western drugses also can not make the people satisfied aspect cure rate, effective percentage very much.The bigger side effect of also existence that has, perhaps drug dose is very big, the course of treatment is very long, it is inconvenient to use.Therefore still there is not a kind of medicine of generally being accepted, generally acknowledge treatment lithangiuria reliable for effect by medical circle so far.
The inventor excavates the square medicine of treatment lithangiuria from Chinese traditional medicine, obtain important breakthrough, through for many years checking, improvement, finishes the present invention again.
The object of the present invention is to provide a kind of medicine with Chinese medicine natural drug preparation, its selection, making and use are all more convenient, and the treatment of lithangiuria is had reliable effect.
Solution of the present invention is based on motherland's medical science to the understanding of lithangiuria with to the understanding of the multiple Chinese herbal medicine property of medicine, by types of drugs compatibility and corresponding processing of medical material processing and preparation method, makes the present invention have good fossil function.
The component of medicine of the present invention comprises following proportion raw material medicine, is expressed as follows with weight portion.Herba Lysimachiae 24-36 Herba Polygoni Perfoliati 24-36 Folium Pyrrosiae 10-20 holds 8-12 Rhizoma Alismatis 15-25 Talcum 40-60 Poria 10-20 Caulis Aristolochiae Manshuriensis 10-20 Polyporus 10-20 Rhizoma Imperatae 24-36 Radix Curcumae 20-30 potassium chloride 4-6
Above crude drug can be manufactured dosage forms such as tablet, honeyed pill, water pill, capsule, granular pattern electuary by normally used pharmaceutical technique method of modern times.
The method of making honeyed pill is, with Herba Lysimachiae, Herba Polygoni Perfoliati, Folium Pyrrosiae, hold, Rhizoma Alismatis, Caulis Aristolochiae Manshuriensis, Polyporus, Rhizoma Imperatae, Radix Curcumae decoct respectively, each decocted liquid medicine is mixed, drop into potassium chloride, make dissolving, with Pulvis Talci, Poria powder be equivalent to the Mel of above medicine total amount about 2/5ths or sucrose joins to mix in the medicinal liquid to rub and rolls evenly, make pill.
The method of making tablet is, with Herba Lysimachiae, Herba Polygoni Perfoliati, Folium Pyrrosiae, hold, Rhizoma Alismatis, Caulis Aristolochiae Manshuriensis, Polyporus, Rhizoma Imperatae, Radix Curcumae decoct respectively, each decocted liquid medicine is mixed, drop into potassium chloride, make dissolving, Pulvis Talci, Poria powder joined in the medicinal liquid to mix to rub roll evenly, airing or oven dry are pulverized.The medicine component of this moment is equivalent to about 3/5ths of crude drug total amount.Add excipient again, tabletting.Do not add Mel or sucrose when making tablet.
More than various dosage forms adult oral doses be equivalent to crude drug 150-200 gram approximately every day, divide 3-5 to take, general logotype 7-14 days is a course of treatment.
Each dosage form of medicine of the present invention is applicable to kidney, ureter, cystolithic treatment.
The inventor uses Drug therapy lithangiuria patient 100 examples of the present invention, male's 68 examples wherein, women's 32 examples; The oldest 67 years old, minimum 14 years old; The course of disease (, ending) 5 years person's 46 examples of less than to accepting Drug therapy of the present invention day from day of angor outbreak first or various inspection means finding lithangiuria day, 10 years person's 38 examples of less than more than 5 years, person's 16 examples more than 10 years.
This group case all has typical clinical manifestation, and the angor history of attack is arranged, and angor is the urine RBC positive between stage of attack.Case about half is respectively through X line radiography or CT or the existence of nuclear magnetic resonance, NMR confirmation calculus.
In treating above-mentioned 100 cases of observation, 2 examples are abandoning cure midway, and 2 examples are implemented operative treatment midway, gets rid of outside statistics, and all the other 96 examples are included the curative effect statistics in.
Therapeutic Method: use bolus of drug of the present invention, tablet or other dosage forms, every day, dosage was equivalent to former medicine 150-200 gram, divide 3-5 time oral.Serveing on 14 is a course of treatment.Listing this group treatment observer in uses 4 courses of treatment at most.Polydipsia water during the treatment.
Angor is frequently sent out the author generally in medication pain disappearance after 5 days.The less calculus of volume generally disappears in week at 2-3.Therapeutic outcome, 74 examples of fully recovering (77.1%), produce effects 9 examples (9.4%), 5 examples that take a turn for the better (5.2%), invalid 8 examples (8.3%), total effective rate is 91.7%.Take medicine of the present invention and do not have bad side effect.
The invention will be further described by the following examples.
Embodiment 1 produces pill
Select medicine and its weight for use: Herba Lysimachiae 3000 gram Herba Polygoni Perfoliati 3000 gram Folium Pyrrosiaes 1500 gram hold 1000 gram Talcums, 5000 gram Poria, 1500 gram Rhizoma Alismatis, 2000 gram Caulis Aristolochiae Manshuriensis, 1500 gram Polyporus, 1500 gram Rhizoma Imperataes, 3000 gram Radix Curcumaes, 2500 gram potassium chloride, 500 grams
Processing technology:
1. Poria is pulverized, crossed 80 mesh sieves, it is standby to get powder.
2. Herba Lysimachiae, Herba Polygoni Perfoliati, Folium Pyrrosiae, are held, Rhizoma Alismatis, Caulis Aristolochiae Manshuriensis, Polyporus, Rhizoma Imperatae, Radix Curcumae decoct respectively.Add 4-6 times of water respectively by each medicine weight before decocting, decoct to the water yield and remain about 1/4, remove slag filter medicinal liquid, with each medicinal liquid mixing for standby use.
3. potassium chloride is joined in the medicinal liquid, make the dissolving mix homogeneously.
4. Pulvis Talci, Poria powder and the Mel that is equivalent to above medicine total amount about 2/5ths are joined to mix in the medicinal liquid to rub and roll evenly, make pill.
Use various crude drug 26 000 grams altogether, make about 2 400 balls of pill, the adult takes 4-8 ball, every day 3-5 time at every turn.General 14 days is a course of treatment.
Embodiment 2 produces tablet Herba Lysimachiae 3500 gram Herba Polygoni Perfoliati 2500 gram Folium Pyrrosiaes 1500 gram and holds 1000 gram Rhizoma Alismatis, 2000 gram Talcums, 6000 gram Poria, 1800 gram Caulis Aristolochiae Manshuriensis, 1200 gram Polyporus, 1100 gram Rhizoma Imperataes, 3200 gram Radix Curcumaes, 2000 gram potassium chloride, 450 grams
Processing technology:
1. Poria is pulverized, crossed 100 mesh sieves, it is standby to get powder.
2. Herba Lysimachiae, Herba Polygoni Perfoliati, Folium Pyrrosiae, are held, Rhizoma Alismatis, Caulis Aristolochiae Manshuriensis, Polyporus, Rhizoma Imperatae, Radix Curcumae decoct respectively.Add 4-6 times of water respectively by each medicine weight before decocting, decoct to the water yield and remain about 1/4, remove slag filter medicinal liquid, with each medicinal liquid mixing for standby use.
3. potassium chloride is joined in the medicinal liquid, make the dissolving mix homogeneously.
4. Pulvis Talci, Poria powder are joined to mix in the medicinal liquid to rub and roll evenly, put oven dry in 40 ℃ of drying baker, pulverize.The medicine component of this moment is equivalent to about 3/5ths of crude drug total amount.Add excipient again, tabletting.
Do not add Mel or sucrose when making tablet.
Claims (5)
1. medicine for the treatment of lithangiuria, it is characterized in that, it is the medicament of being made by the following weight proportion raw material, and Herba Lysimachiae 24-36 Herba Polygoni Perfoliati 24-36 Folium Pyrrosiae 10-20 holds 8-12 Rhizoma Alismatis 15-25 Talcum 40-60 Poria 10-20 Caulis Aristolochiae Manshuriensis 10-20 Polyporus 10-20 Rhizoma Imperatae 24-36 Radix Curcumae 20-30 potassium chloride 4-6.
2. the medicine of treatment lithangiuria according to claim 1 is characterized in that, said medicament is a said dosage form on any pharmaceutics.
3. the medicine of treatment lithangiuria according to claim 2 is characterized in that, said medicament is pill or tablet.
4. the preparation method of the bolus of drug of treatment lithangiuria according to claim 3, it is characterized in that, with Herba Lysimachiae, Herba Polygoni Perfoliati, Folium Pyrrosiae, hold, Rhizoma Alismatis, Caulis Aristolochiae Manshuriensis, Polyporus, Rhizoma Imperatae, Radix Curcumae decoct respectively, each decocted liquid medicine is mixed, drop into potassium chloride, Pulvis Talci, Poria powder and be equivalent to the Mel of above medicine total amount about 2/5ths or sucrose mixes to rub and is rolled into pill.
5. the preparation method of treatment lithangiuria medicinal tablet according to claim 3, it is characterized in that, with Herba Lysimachiae, Herba Polygoni Perfoliati, Folium Pyrrosiae, hold, Rhizoma Alismatis, Caulis Aristolochiae Manshuriensis, Polyporus, Rhizoma Imperatae, Radix Curcumae decoct respectively, each decocted liquid medicine is mixed, drop into potassium chloride, Pulvis Talci, Poria powder, mix to rub and roll evenly, airing or oven dry, pulverize, add excipient again, tabletting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00124371 CN1101208C (en) | 2000-09-11 | 2000-09-11 | Medicine for treating uninary calculaus and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00124371 CN1101208C (en) | 2000-09-11 | 2000-09-11 | Medicine for treating uninary calculaus and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1298719A CN1298719A (en) | 2001-06-13 |
| CN1101208C true CN1101208C (en) | 2003-02-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00124371 Expired - Fee Related CN1101208C (en) | 2000-09-11 | 2000-09-11 | Medicine for treating uninary calculaus and its preparing process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1101208C (en) |
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2000
- 2000-09-11 CN CN 00124371 patent/CN1101208C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1298719A (en) | 2001-06-13 |
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