CN110101805A - Pure plant rhinitis conditioning liquid and preparation method thereof - Google Patents

Pure plant rhinitis conditioning liquid and preparation method thereof Download PDF

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Publication number
CN110101805A
CN110101805A CN201910480510.6A CN201910480510A CN110101805A CN 110101805 A CN110101805 A CN 110101805A CN 201910480510 A CN201910480510 A CN 201910480510A CN 110101805 A CN110101805 A CN 110101805A
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rhinitis
parts
conditioning liquid
pure plant
preparation
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刘春雨
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Suzhou Zhishi Biotechnology Co Ltd
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Suzhou Zhishi Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538—Schizonepeta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides a kind of pure plant rhinitis conditioning liquid and preparation method thereof, wherein the pure plant rhinitis conditioning liquid includes following component: menthol, mustard a species of orchid, licorice, honeysuckle, chrysanthemum, cordate houttuynia, Asiatic plantain, elm skin, mulberry leaf, lophatherum gracile.Pure plant rhinitis conditioning liquid of the invention has pure plant component, has no toxic side effect, and rhinitis tool is had a better effect, with good application prospect.

Description

Pure plant rhinitis conditioning liquid and preparation method thereof
Technical field
The present invention relates to the rhinitis conditioning liquids and its preparation side of a kind of rhinitis conditioning liquid more particularly to a kind of pure plant component Method.
Background technique
Modern life rhythm is very fast, and endocrine disorder and environmental pollution are got worse, and rhinitis disease incidence is in rising trend, Clinically common rhinitis situation is mostly nose resistance (concha is loose), and secretion increases, nasal decongestion, bleeding or erosion, few Number is atrophic rhinitis, i.e. mucous membrane severe is rotten to the corn, and concha is eliminated, and more has many allergic rhinitises, daily to sneeze, runny nose. And rhinitis radical cure difficulty is larger easy to recur at present, administration time is long, increases the economy and mental burden of patient, many patient's warps It is not cured long, even finally developing into nasosinusitis, nasopharyngeal carcinoma, the preparation for treating rhinitis sold on this life face, point oral and external application takes orally system Agent dosage is big, and much has drowsiness sense after taking containing western medicine compositions, patients such as chlorpheniramines, influence work and life；External application Medicine generally uses aqua collunarium, and nose drops water instills nasal cavity and often pollutes oral cavity, while collunarium aqua is volatile, and drug effect is lasting Time is short, affects the treatment, and using conventional antimicrobial element intravenous administration, therapeutic effect is not very good.Therefore, for how above-mentioned asking Topic, it is necessary to propose further solution.
Summary of the invention
The purpose of the present invention is to provide a kind of pure plant rhinitis conditioning liquids and preparation method thereof, to overcome in the prior art Existing deficiency.
For achieving the above object, the present invention provides a kind of pure plant rhinitis conditioning liquid comprising following component: peppermint Brain, mustard a species of orchid, licorice, honeysuckle, chrysanthemum, cordate houttuynia, Asiatic plantain, elm skin, mulberry leaf, lophatherum gracile.
As the improvement of pure plant rhinitis conditioning liquid of the invention, the pure plant rhinitis conditioning liquid includes such as by mass parts Lower component: 2-5 parts of menthol, 4-6 parts of mustard a species of orchid, 3-6 parts of licorice, 9-10 parts of honeysuckle, 5.5-7.8 parts of chrysanthemum, cordate houttuynia 1.2-4.3 parts, 6.7-10.2 parts of Asiatic plantain, 6-10 parts of elm skin, 8-12 parts of mulberry leaf, 3-7 parts of lophatherum gracile, remaining is water.
For achieving the above object, the present invention provides a kind of preparation side of pure plant rhinitis conditioning liquid as described above Method comprising following steps:
S1, each component in pure plant rhinitis conditioning liquid is weighed according to the weight ratio；
S2, weighed each group is placed in pure water, carries out giving up in advance under conditions of 90-100 DEG C and boil 1-2h, after useless boils Mixture be filtered；
S3, the solid matter being obtained by filtration in step S2 is dried at room temperature, and carry out wall cell disruption powder it is broken and sieving, obtain demand The powder of particle size；
S3, by the powder of obtained each component under conditions of 145-160 DEG C maturation process；
S4, maturation process powder after cooling, each powder is mixed, and stirs evenly；
S5, obtained mixed-powder is subjected to immersion 15-18h with the ethyl alcohol of 4-5 times of parts by weight, and gives up and boils 60-90min, it is useless to boil After cooling, the dregs of a decoction of filtering removal bottom deposit；
S6, the filtrate that step S2 is obtained is mixed with the obtained filtrate of step S5, is sufficiently stirred and distills removal ethyl alcohol；
S7, the mixture for obtaining step S6 carry out sterilization treatment under conditions of 120-130 DEG C, obtain pure plant of the invention Rhinitis conditioning liquid.
The improvement of preparation method as pure plant rhinitis conditioning liquid of the invention, step S2 further include: by each component benefit It is washed with ethanol solution, each group is placed in pure water again after distillation removal ethyl alcohol.
The improvement of preparation method as pure plant rhinitis conditioning liquid of the invention carries out using model when broken wall The breaking-wall cell machine of the Ultramicro-powder grade of sjy5-8.
The improvement of preparation method as pure plant rhinitis conditioning liquid of the invention, when sieving, used sieve is 200-300 mesh.
The improvement of preparation method as pure plant rhinitis conditioning liquid of the invention, the system of the pure plant rhinitis conditioning liquid In Preparation Method, after step S5 further include: the obtained dregs of a decoction are carried out immersion 18-20h with the ethyl alcohol of 4-5 times of parts by weight, and are given up 70-100min is boiled, is given up after boiling cooling, the dregs of a decoction of filtering bottom deposition obtain obtained filtrate and step S1 and step S5 Filtrate mixes together.
Compared with prior art, the beneficial effects of the present invention are: pure plant rhinitis conditioning liquid of the invention has pure plant Ingredient has no toxic side effect, and treatment rhinitis tool is had a better effect, with good application prospect.
Specific embodiment
Below with reference to each embodiment, the present invention is described in detail, but it should be stated that, these embodiments are not Limitation of the present invention, those of ordinary skill in the art are according to these embodiments in made function, method or structure Equivalent transformation or substitution, all belong to the scope of protection of the present invention within.
The present invention provides menthol, mustard a species of orchid, licorice, honeysuckle, chrysanthemum, cordate houttuynia, Asiatic plantain, elm skin, mulberry leaf, henon bamboo Leaf.Preferably, the pure plant rhinitis conditioning liquid includes following component by mass parts: 2-5 parts of menthol, 4-6 parts of mustard a species of orchid, life are sweet 3-6 parts careless, 9-10 parts of honeysuckle, 5.5-7.8 parts of chrysanthemum, 1.2-4.3 parts of cordate houttuynia, 6.7-10.2 parts of Asiatic plantain, elm skin 6-10 Part, 8-12 parts of mulberry leaf, 3-7 parts of lophatherum gracile, remaining is water.
Below with reference to specific preparation method embodiment, the technical solution of pure plant rhinitis conditioning liquid of the invention is carried out It illustrates.
Embodiment 1
Weigh 2 parts of menthol, 4 parts of mustard a species of orchid, 3 parts of licorice, 9 parts of honeysuckle, 5.5 parts of chrysanthemum, 1.2 parts of cordate houttuynia, Asiatic plantain 6.7 Part, 6 parts of elm skin, 8 parts of mulberry leaf, 3 parts of lophatherum gracile, remaining is water.Each component is washed using ethanol solution, distillation removal second Each group is placed in pure water again after alcohol, carries out giving up in advance under conditions of 90 DEG C and boils 1h, the mixture after useless boil is carried out Filtering.The solid matter being obtained by filtration is dried at room temperature, uses the breaking-wall cell machine of the Ultramicro-powder grade of model sjy5-8 Broken wall crushing is carried out, is then sieved using the sieve of 200 mesh, the powder of demand particle size is obtained.The each group that will be obtained The powder of part maturation process under conditions of 145 DEG C.After cooling, each powder is mixed, and stirs for the powder of maturation process It mixes uniformly.Obtained mixed-powder is subjected to immersion 15h with the ethyl alcohol of 4 times of parts by weight, and gives up and boils 60min, is given up after boiling cooling, mistake Filter off the dregs of a decoction for removing bottom deposit.The filtrate that the filtrate being obtained by filtration for the second time is obtained by filtration with first time is mixed, is sufficiently stirred It mixes and distills removal ethyl alcohol.Obtained mixture is subjected to sterilization treatment under conditions of 120 DEG C, obtains pure plant of the invention Rhinitis conditioning liquid.
Embodiment 2
Weigh 5 parts of menthol, 6 parts of mustard a species of orchid, 6 parts of licorice, 10 parts of honeysuckle, 7.8 parts of chrysanthemum, 4.3 parts of cordate houttuynia, Asiatic plantain 10.2 parts, 10 parts of elm skin, 12 parts of mulberry leaf, 7 parts of lophatherum gracile, remaining is water.Each component is washed using ethanol solution, is distilled Each group is placed in pure water again after removal ethyl alcohol, carries out giving up in advance under conditions of 100 DEG C and boils 2h, to the mixing after useless boil Object is filtered.The solid matter being obtained by filtration is dried at room temperature, uses the cell of the Ultramicro-powder grade of model sjy5-8 Wall-breaking machine carries out broken wall crushing, is then sieved using the sieve of 300 mesh, obtains the powder of demand particle size.It will obtain Each component powder under conditions of 160 DEG C maturation process.After cooling, each powder is mixed for the powder of maturation process It closes, and stirs evenly.Obtained mixed-powder is subjected to immersion 18h with the ethyl alcohol of 5 times of parts by weight, and gives up and boils 90min, giving up, it is cold to boil But after, the dregs of a decoction of filtering removal bottom deposit.The obtained dregs of a decoction are subjected to immersion 18-20h with the ethyl alcohol of 4-5 times of parts by weight, and It is useless to boil 70-100min, it gives up after boiling cooling, the dregs of a decoction of filtering removal bottom deposit.The filtrate being obtained by filtration three times is sufficiently stirred And distill removal ethyl alcohol.Obtained mixture is subjected to sterilization treatment under conditions of 130 DEG C, obtains pure plant nose of the invention Scorching conditioning liquid.
It is verified below by toxicity of the following toxicological experiment to pure plant rhinitis conditioning liquid of the invention:
Adult guinea pig 6 are chosen, male and female each 3, pure plant rhinitis conditioning liquid of the invention is placed in globefish according to same dose On the right side of mouse on buccal mucosa, the drug paste for being impregnated with pure plant rhinitis conditioning liquid of the invention specifically can be used.Continue 2 hours, daily 3 It is secondary.Finally successively after medication, respectively in 2h, 12h, respectively select 1 cavy for 24 hours, take its right side medication buccal mucosa, while left side is made For control, pathological section is made, is observed under an optical microscope.It is observed that property is without significant change.It follows that of the invention Pure plant rhinitis conditioning liquid has no toxic side effect.
In conclusion pure plant rhinitis conditioning liquid of the invention has pure plant component, have no toxic side effect, for treatment Human oral cavity ulcer tool has a better effect, with good application prospect.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims Variation is included within the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (7)

1. a kind of pure plant rhinitis conditioning liquid, which is characterized in that the pure plant rhinitis conditioning liquid includes following component: peppermint Brain, mustard a species of orchid, licorice, honeysuckle, chrysanthemum, cordate houttuynia, Asiatic plantain, elm skin, mulberry leaf, lophatherum gracile.
2. pure plant rhinitis conditioning liquid according to claim 1, which is characterized in that the pure plant rhinitis conditioning liquid presses matter Measuring part includes following component: 2-5 parts of menthol, 4-6 parts of mustard a species of orchid, 3-6 parts of licorice, 9-10 parts of honeysuckle, chrysanthemum 5.5-7.8 Part, 1.2-4.3 parts of cordate houttuynia, 6.7-10.2 parts of Asiatic plantain, 6-10 parts of elm skin, 8-12 parts of mulberry leaf, 3-7 parts of lophatherum gracile, remaining is Water.
3. a kind of preparation method of pure plant rhinitis conditioning liquid according to claim 1 or 2, which is characterized in that the system Preparation Method includes the following steps:
S1, each component in pure plant rhinitis conditioning liquid is weighed according to the weight ratio；
S2, weighed each group is placed in pure water, carries out giving up in advance under conditions of 90-100 DEG C and boil 1-2h, after useless boils Mixture be filtered；
S3, the solid matter being obtained by filtration in step S2 is dried at room temperature, and carry out wall cell disruption powder it is broken and sieving, obtain demand The powder of particle size；
S3, by the powder of obtained each component under conditions of 145-160 DEG C maturation process；
S4, maturation process powder after cooling, each powder is mixed, and stirs evenly；
S5, obtained mixed-powder is subjected to immersion 15-18h with the ethyl alcohol of 4-5 times of parts by weight, and gives up and boils 60-90min, it is useless to boil After cooling, the dregs of a decoction of filtering removal bottom deposit；
S6, the filtrate that step S2 is obtained is mixed with the obtained filtrate of step S5, is sufficiently stirred and distills removal ethyl alcohol；
S7, the mixture for obtaining step S6 carry out sterilization treatment under conditions of 120-130 DEG C, obtain pure plant of the invention Rhinitis conditioning liquid.
4. the preparation method of pure plant rhinitis conditioning liquid according to claim 3, which is characterized in that step S2 further include: Each component is washed using ethanol solution, each group is placed in pure water again after distillation removal ethyl alcohol.
5. the preparation method of pure plant rhinitis conditioning liquid according to claim 3, which is characterized in that carry out use when broken wall The breaking-wall cell machine of the Ultramicro-powder grade of model sjy5-8.
6. the preparation method of pure plant rhinitis conditioning liquid according to claim 3, which is characterized in that when sieving, used Sieve be 200-300 mesh.
7. the preparation method of pure plant rhinitis conditioning liquid according to claim 3, which is characterized in that the pure plant rhinitis In the preparation method of conditioning liquid, after step S5 further include: impregnate the obtained dregs of a decoction with the ethyl alcohol of 4-5 times of parts by weight 18-20h, and give up and boil 70-100min, it gives up after boiling cooling, the dregs of a decoction of filtering bottom deposition, by obtained filtrate and step S1 and step The filtrate that rapid S5 is obtained mixes together.
CN201910480510.6A 2019-06-04 2019-06-04 Pure plant rhinitis conditioning liquid and preparation method thereof Pending CN110101805A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114569672A (en) * 2020-12-01 2022-06-03 青岛权道管理咨询有限公司 Rhinitis spray and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102293832A (en) * 2011-08-13 2011-12-28 胡佳顶 Traditional Chinese medicinal composition for treating rhinitis
CN102440929A (en) * 2011-12-27 2012-05-09 郑州大学 Compound wild chrysanthemum spraying agent

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102293832A (en) * 2011-08-13 2011-12-28 胡佳顶 Traditional Chinese medicinal composition for treating rhinitis
CN102440929A (en) * 2011-12-27 2012-05-09 郑州大学 Compound wild chrysanthemum spraying agent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114569672A (en) * 2020-12-01 2022-06-03 青岛权道管理咨询有限公司 Rhinitis spray and preparation method thereof

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