CN110101619A - A kind of compound of Reduce allergy and preparation method thereof - Google Patents
A kind of compound of Reduce allergy and preparation method thereof Download PDFInfo
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- CN110101619A CN110101619A CN201910458605.8A CN201910458605A CN110101619A CN 110101619 A CN110101619 A CN 110101619A CN 201910458605 A CN201910458605 A CN 201910458605A CN 110101619 A CN110101619 A CN 110101619A
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- 206010020751 Hypersensitivity Diseases 0.000 title claims abstract description 47
- 208000026935 allergic disease Diseases 0.000 title claims abstract description 47
- 230000007815 allergy Effects 0.000 title claims abstract description 47
- 150000001875 compounds Chemical class 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 36
- 235000001674 Agaricus brunnescens Nutrition 0.000 claims abstract description 31
- 229920001503 Glucan Polymers 0.000 claims abstract description 30
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims abstract description 30
- 229960003966 nicotinamide Drugs 0.000 claims abstract description 29
- 235000005152 nicotinamide Nutrition 0.000 claims abstract description 29
- 239000011570 nicotinamide Substances 0.000 claims abstract description 29
- 239000000284 extract Substances 0.000 claims description 9
- 238000000926 separation method Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 3
- 244000025254 Cannabis sativa Species 0.000 claims 1
- 241000246500 Gentianella aspera Species 0.000 claims 1
- 210000000232 gallbladder Anatomy 0.000 claims 1
- 201000004624 Dermatitis Diseases 0.000 abstract description 22
- 230000000172 allergic effect Effects 0.000 abstract description 10
- 208000010668 atopic eczema Diseases 0.000 abstract description 10
- 238000011084 recovery Methods 0.000 abstract description 10
- 208000024891 symptom Diseases 0.000 abstract description 10
- 239000002537 cosmetic Substances 0.000 abstract description 9
- 238000013329 compounding Methods 0.000 abstract description 5
- 210000003491 skin Anatomy 0.000 description 14
- 230000000052 comparative effect Effects 0.000 description 13
- 239000000126 substance Substances 0.000 description 9
- 230000000694 effects Effects 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 4
- 235000002722 Dioscorea batatas Nutrition 0.000 description 3
- 235000006536 Dioscorea esculenta Nutrition 0.000 description 3
- 240000001811 Dioscorea oppositifolia Species 0.000 description 3
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 230000000638 stimulation Effects 0.000 description 3
- 230000002052 anaphylactic effect Effects 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 210000004927 skin cell Anatomy 0.000 description 2
- 206010027654 Allergic conditions Diseases 0.000 description 1
- 206010012442 Dermatitis contact Diseases 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 208000002029 allergic contact dermatitis Diseases 0.000 description 1
- 210000003651 basophil Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000000586 desensitisation Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 235000004879 dioscorea Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000008076 immune mechanism Effects 0.000 description 1
- 230000007233 immunological mechanism Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- -1 nicotinoyl Amine Chemical class 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 235000021259 spicy food Nutrition 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to cosmetic fields, provide a kind of compound and preparation method thereof of Reduce allergy, the allergic problem for rapid recovery skin.The compound of a kind of Reduce allergy provided by the invention, comprising: 50 ~ 70 mass parts of water, 10 ~ 20 mass parts of radix gentianae extracting solution, 10 ~ 20 mass parts of mushroom glucan, 10 ~ 20 mass parts of niacinamide.By compounding radix gentianae, mushroom glucan and niacinamide, the compound of available rapid recovery skin allergy can quickly alleviate skin allergy symptom, alleviate the pain of patient.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of compound of Reduce allergy and preparation method thereof.
Background technique
The definition of allergy is there are many version, in order to illustrate this major issue and ensure that medical worker is unified at one
It is exchanged in concept, WHO is recommended to use definition and the term of a set of international uniform.Skin allergy refers to the height induced by immunologic mechanism
Quick reaction.Allergy can be what body fluid (antibody) either cellular immune mechanism mediated.Allergy is a kind of allergy of body,
It is a kind of abnormal reaction of the people to koinomatter (anaphylactogen), when the crowd that anaphylactogen touches allergic constitution can just occur
Allergy, anaphylactogen have several hundred kinds of pollen, dust, foreign protein, chemical substance, ultraviolet light etc..In anaphylactoid generating process
In, Anaphylactic mediator plays direct effect, and anaphylactogen is the external cause that allergic condition occurs, and machine immunocompetence is low, largely certainly
It is the internal cause that allergy occurs by Oxidative demage of the base to mast cell and basophil.
The pathogenic factor of skin allergy includes internal factor, and two broad aspect of external factor: internal factor is exactly to have in itself
Allergic constitution, this plays a leading role in the morbidity of skin allergy.Thoroughly desensitization is that treatment skin allergy prevents recurrence early
It is crucial.
External factor is also very much.Including diet, inhalation (inhalatio), weather, contact allergy object factor etc..Wherein seafood, protein,
Spicy food, wine, sucking pollen, dust mite, cold snap, contact chemical substance, soap, detergent etc. are that skin allergy is most common
Inducement.
Most typical cosmetic allergic contact dermatitis is essence allergy, and the cosmetics containing alcoholic content such as astringent lotion also can be to skin
Generate certain stimulation.Other such as biochemical preservatives, tartaric acid can all cause different stimulations to different skin.
Certain in cosmetics cause skin allergy at branch, generate stimulation to Skin Cell, generate Skin Cell anti-
Body, so as to cause allergy.If, cannot be arbitrarily general dermopathic using treatment since cosmetics improper use causes skin allergy
Otherwise ointment can cause pachylosis, play color spot, aggravate skin disease.
The transdermal low efficiency of common external cosmetics, it is low into effect ingredient solubility inside skin, it can only be from skin
Surface layer improves skin allergy symptom, and specific aim is very single, palliative.Some may contain stimulating component to externally applied product,
Hormone, harmful chemical component, directly contact injury skin.
Meanwhile the complicated component of the cosmetics of existing Reduce allergy, it takes effect relatively slow, it cannot quickly Reduce allergy
Symptom.
Summary of the invention
Present invention solves the technical problem that being the allergic problem of rapid recovery skin, a kind of compound of Reduce allergy is provided
And preparation method thereof.
In order to solve the above technical problem, the present invention provides technical solution are as follows:
A kind of compound of Reduce allergy, comprising: 50 ~ 70 mass parts of water, 10 ~ 20 mass parts of radix gentianae extracting solution, mushroom Portugal are poly-
Sugared 10 ~ 20 mass parts, 10 ~ 20 mass parts of niacinamide.
By compounding radix gentianae, mushroom glucan and niacinamide, available rapid recovery skin allergy is answered
Close object.
Can be with the allergic symptom of rapid recovery skin, simple production process, production cost is low, can quickly promote.
Preferably, 60 ~ 70 mass parts of water, 15 ~ 20 mass parts of radix gentianae extracting solution, 10 ~ 20 mass of mushroom glucan
Part, 15 ~ 20 mass parts of niacinamide.The use for alleviating skin allergy is substantially reduced by the content of various substances in preferred compound
When.
Preferably, 60 mass parts of water, 15 mass parts of radix gentianae extracting solution, 10 mass parts of mushroom glucan, niacinamide
15 mass parts.
Preferably, the radix gentianae extracting solution the preparation method comprises the following steps: take radix gentianae, soak in water 50 ~ 60min, be added 7 ~
The water of 15 times of amounts extracts 1 ~ 2h, obtains the first extracting solution；The first extracting solution and the dregs of a decoction are separated, 4 ~ 8 times of amounts are added into the dregs of a decoction
Water extracts 3 ~ 4h, obtains the second extracting solution；The second extracting solution and the dregs of a decoction are separated, the water of 2 ~ 5 times of amounts is added into the dregs of a decoction, obtains
Third extracting solution after separation, merges the first, second, third extracting solution, the extracting solution after merging is concentrated 5 for quality of medicinal material ~
7 times/ml, obtain radix gentianae extracting solution.Radix gentianae is repeatedly extracted, it can be to greatest extent by the effective substance in radix gentianae extracting solution
Matter extracts, and after the same niacinamide of extract, mushroom glucan are compound, can quickly alleviate skin allergy.
A kind of preparation method of compound that alleviating skin allergy, by water, radix gentianae extracting solution, mushroom glucan, nicotinoyl
Amine is added in ultrasonic wave homogenizer, and homogeneous power is 1kW, 25 ~ 40min of homogenizing time, the compound for the allergy that is eased.
Compared with prior art, the device have the advantages that are as follows: by by radix gentianae, mushroom glucan and niacinamide
It is compounded, the compound of available rapid recovery skin allergy, has obtained significantly subtracting the time required to alleviating skin allergy
It is few, alleviate the pain of autopath.
Specific embodiment
It the following examples are further illustrations of the invention, is not limitation of the present invention.
Embodiment 1
A kind of compound of Reduce allergy, including 60 mass parts of water, 15 mass parts of radix gentianae extracting solution, 10 matter of mushroom glucan
Measure part, 15 mass parts of niacinamide.Water, radix gentianae extracting solution, mushroom glucan, niacinamide are added in ultrasonic wave homogenizer,
Homogeneous power is 1kW, 25 ~ 40min of homogenizing time, the compound for the allergy that is eased.
By compounding radix gentianae, mushroom glucan and niacinamide, available rapid recovery skin allergy is answered
Close object.Can be with the allergic symptom of rapid recovery skin, simple production process, production cost is low, can quickly promote.By excellent
The content of various substances in compound is selected to be substantially reduced the used time for alleviating skin allergy.Radix gentianae is repeatedly extracted, it can be maximum
Limit extracts the active principle in radix gentianae extracting solution, can be with after the same niacinamide of extract, mushroom glucan are compound
Quickly alleviate skin allergy.
Embodiment 2
A kind of compound of Reduce allergy, comprising: 50 mass parts of water, 10 mass parts of radix gentianae extracting solution, 10 matter of mushroom glucan
Measure part, 10 mass parts of niacinamide.Water, radix gentianae extracting solution, mushroom glucan, niacinamide are added in ultrasonic wave homogenizer,
Homogeneous power is 1kW, 25 ~ 40min of homogenizing time, the compound for the allergy that is eased.
Embodiment 3
A kind of compound of Reduce allergy, comprising: 70 mass parts of water, 20 mass parts of radix gentianae extracting solution, 20 matter of mushroom glucan
Measure part, 20 mass parts of niacinamide.Water, radix gentianae extracting solution, mushroom glucan, niacinamide are added in ultrasonic wave homogenizer,
Homogeneous power is 1kW, 25 ~ 40min of homogenizing time, the compound for the allergy that is eased.
Embodiment 4
A kind of compound of Reduce allergy, comprising: 50 mass parts of water, 10 mass parts of radix gentianae extracting solution, 10 matter of mushroom glucan
Measure part, 10 mass parts of niacinamide.The radix gentianae extracting solution the preparation method comprises the following steps: take radix gentianae, soak in water 50 ~ 60min, add
Enter the water of 7 ~ 15 times of amounts, extracts 1 ~ 2h, obtain the first extracting solution；The first extracting solution and the dregs of a decoction are separated, 4 ~ 8 times are added into the dregs of a decoction
The water of amount extracts 3 ~ 4h, obtains the second extracting solution；The second extracting solution and the dregs of a decoction are separated, the water of 2 ~ 5 times of amounts is added into the dregs of a decoction,
Third extracting solution is obtained, after separation, merges the first, second, third extracting solution, the extracting solution after merging is concentrated as quality of medicinal material
5 ~ 7 times/ml, obtain radix gentianae extracting solution.Ultrasonic wave homogeneous is added in water, radix gentianae extracting solution, mushroom glucan, niacinamide
In equipment, homogeneous power is 1kW, 25 ~ 40min of homogenizing time, the compound for the allergy that is eased.
Comparative example 1
A kind of compound of Reduce allergy, comprising: 75 mass parts of water, 10 mass parts of mushroom glucan, 15 mass parts of niacinamide.
Comparative example 2
A kind of compound of Reduce allergy, comprising: 70 mass parts of water, 15 mass parts of radix gentianae extracting solution, 15 mass of niacinamide
Part.
Comparative example 3
A kind of compound of Reduce allergy, comprising: 75 mass parts of water, 15 mass parts of radix gentianae extracting solution, 10 matter of mushroom glucan
Measure part.
Comparative example 4
A kind of compound of Reduce allergy, comprising: 85 mass parts of water, 15 mass parts of radix gentianae extracting solution.
Comparative example 5
A kind of compound of Reduce allergy, comprising: 90 mass parts of water, 10 mass parts of mushroom glucan.
Comparative example 6
A kind of compound of Reduce allergy, comprising: 85 mass parts of water, 15 mass parts of niacinamide.
Comparative example 7
A kind of compound of Reduce allergy, comprising: 100 mass parts of water.
Experimental example
20 volunteers are randomly selected, men and women is fifty-fifty, and the age, interior both hands inboard arm must not for 24 hours before test between 20 ~ 35 years old
Using any cosmetics, test starts preceding wash hands inboard arm and dries.In tested volunteer's inboard arm marking pen
Picture takes 5 regions 3cm*3cm, after uniformly being smeared in defined area 30 seconds, 2 minutes with the fresh Chinese yam of 5mm thickness slice by
The region that examination volunteer smears yam slices starts to generate skin sensitivity stress reaction, if not selecting without this reaction is observed
The volunteer tests.Formulation examples 1, the experimental comparison group 1, experiment contrast of 5ml are uniformly smeared in 5 tested regions respectively
It organizes the sample of 2, experimental comparison group 3 and blank control group and starts timing, since record stress to skin sensitivity smearing sample
Reaction alleviates elapsed time and takes its average value.
As can be known from the above table, skin sensitivity stress reaction is significantly less than comparative example 1 ~ 4, table the time required to alleviating in embodiment 1
The formula of bright the application can be with rapid recovery skin allergy.
The preparation method of radix gentianae extracting solution is optimized in embodiment 4, can also quickly alleviate skin mistake
It is quick.
In comparative example 1, is compounded using mushroom glucan with niacinamide, radix gentianae extracting solution is not added；In comparative example 2, adopt
It is compounded with radix gentianae extracting solution with niacinamide, mushroom glucan is not added；It is multiple using radix gentianae and mushroom glucan in comparative example 3
Match, niacinamide is not added.Although corresponding three kinds of compounds have the effect of certain Reduce allergy, alleviate skin allergy
The required time is longer, can not quickly Reduce allergy symptom, show that the various substances in the application are individually or multiple two-by-two
With can react to a certain extent with Reduce allergy, but effective it is weaker than three's compounding.
In comparative example 4 ~ 6, individual mushroom glucan, niacinamide or radix gentianae extracting solution are selected, with the sky of comparative example 7
White addition is compared, and three kinds of substances have the effect of certain Reduce allergy, but the time used in Reduce allergy is compared with embodiment 1 ~ 4
Longer, rapid recovery allergic symptom caused by compound cannot all be reached by showing to be used alone any one of substance in upper
Effect.
Alleviation skin allergy elapsed time is most short in embodiment 1, has more significant difference, table with embodiment 2 ~ 4
Bright radix gentianae extracting solution, niacinamide, mushroom glucan according to certain proportion carry out compounding can further improve it is compound
The effect of object alleviation skin allergic symptom.The allergic symptom that the user to Succus Rhizoma Dioscoreae allergy can especially be alleviated, can be quick
Alleviation user allergic symptom.A kind of natural adding ingredient of the Chinese yam as skin care item, has been obtained and is widely applied, but
It is in the juice in Chinese yam but containing a large amount of ingredient for causing allergy.
Above-listed detailed description is illustrating for possible embodiments of the present invention, and above embodiments are not to limit this
The scope of the patents of invention, all equivalence enforcements or change without departing from carried out by the present invention, is intended to be limited solely by the scope of the patents of this case.
Claims (5)
1. a kind of compound of Reduce allergy characterized by comprising 50 ~ 70 mass parts of water, 10 ~ 20 matter of radix gentianae extracting solution
Measure part, 10 ~ 20 mass parts of mushroom glucan, 10 ~ 20 mass parts of niacinamide.
2. a kind of compound of Reduce allergy according to claim 1, which is characterized in that 60 ~ 70 mass parts of water, dragon
15 ~ 20 mass parts of gallbladder grass extracting solution, 10 ~ 20 mass parts of mushroom glucan, 15 ~ 20 mass parts of niacinamide.
3. a kind of compound of Reduce allergy according to claim 2, which is characterized in that 60 mass parts of water, rough gentian
Careless 15 mass parts of extracting solution, 10 mass parts of mushroom glucan, 15 mass parts of niacinamide.
4. a kind of compound of Reduce allergy according to claim 1, which is characterized in that the system of the radix gentianae extracting solution
Preparation Method are as follows: take radix gentianae, soak in water 50 ~ 60min, the water of 7 ~ 15 times of amounts is added, extract 1 ~ 2h, obtain the first extracting solution；
The first extracting solution and the dregs of a decoction are separated, the water of 4 ~ 8 times of amounts is added into the dregs of a decoction, 3 ~ 4h is extracted, obtains the second extracting solution；Separation second
The water of 2 ~ 5 times of amounts is added into the dregs of a decoction, obtains third extracting solution for extracting solution and the dregs of a decoction, after separation, merges first, second, third
Extracting solution after merging is concentrated 5 ~ 7 times/ml for quality of medicinal material, obtains radix gentianae extracting solution by extracting solution.
5. a kind of preparation method of the compound of Reduce allergy, which is characterized in that by water, radix gentianae extracting solution, mushroom glucan,
Niacinamide be added ultrasonic wave homogenizer in, homogeneous power be 1kW, 25 ~ 40min of homogenizing time, the allergy that is eased it is compound
Object.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910458605.8A CN110101619A (en) | 2019-05-29 | 2019-05-29 | A kind of compound of Reduce allergy and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910458605.8A CN110101619A (en) | 2019-05-29 | 2019-05-29 | A kind of compound of Reduce allergy and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
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| CN110101619A true CN110101619A (en) | 2019-08-09 |
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| CN201910458605.8A Pending CN110101619A (en) | 2019-05-29 | 2019-05-29 | A kind of compound of Reduce allergy and preparation method thereof |
Country Status (1)
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267075A (en) * | 2014-06-27 | 2016-01-27 | 天津强微特生物科技有限公司 | Inflammation-diminishing anti-allergy facial cleanser |
| CN109260094A (en) * | 2018-11-20 | 2019-01-25 | 上海悦目化妆品有限公司 | A kind of composition and preparation method thereof containing plant antiallergic ingredient |
-
2019
- 2019-05-29 CN CN201910458605.8A patent/CN110101619A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267075A (en) * | 2014-06-27 | 2016-01-27 | 天津强微特生物科技有限公司 | Inflammation-diminishing anti-allergy facial cleanser |
| CN109260094A (en) * | 2018-11-20 | 2019-01-25 | 上海悦目化妆品有限公司 | A kind of composition and preparation method thereof containing plant antiallergic ingredient |
Non-Patent Citations (1)
| Title |
|---|
| 顾有守: "《顾有守皮肤病诊断和治疗精选》", 30 April 2009, 广东科技出版社 * |
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Application publication date: 20190809 |