CN110074823A - Saliva collection apparatus - Google Patents
Saliva collection apparatus Download PDFInfo
- Publication number
- CN110074823A CN110074823A CN201910468084.4A CN201910468084A CN110074823A CN 110074823 A CN110074823 A CN 110074823A CN 201910468084 A CN201910468084 A CN 201910468084A CN 110074823 A CN110074823 A CN 110074823A
- Authority
- CN
- China
- Prior art keywords
- sampling
- liquid storage
- cylinder
- detection container
- saliva
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000003296 saliva Anatomy 0.000 title claims abstract description 65
- 238000005070 sampling Methods 0.000 claims abstract description 102
- 238000001514 detection method Methods 0.000 claims abstract description 52
- 238000012360 testing method Methods 0.000 claims abstract description 50
- 239000007788 liquid Substances 0.000 claims abstract description 48
- 230000008859 change Effects 0.000 claims description 6
- 238000007689 inspection Methods 0.000 claims description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical group [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 3
- 229910052782 aluminium Inorganic materials 0.000 claims description 3
- 239000004411 aluminium Substances 0.000 claims description 3
- 238000002845 discoloration Methods 0.000 claims description 3
- 238000002791 soaking Methods 0.000 claims description 2
- 238000009736 wetting Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 8
- 230000008569 process Effects 0.000 abstract description 5
- 238000007789 sealing Methods 0.000 description 13
- 230000002093 peripheral effect Effects 0.000 description 5
- 230000004323 axial length Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000011358 absorbing material Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000005213 imbibition Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
Abstract
The present invention provides a kind of saliva collection apparatus, it includes detection container (300) and sampling component, sampling component includes the sampling body (200) for absorbing saliva sample, the base wall (302) of detection container (300) has through-hole, the periphery of through-hole is connected with the liquid storage cylinder (301) for being contained in the inner cavity of detection container (300), liquid storage cylinder (301) is perforation in the axial direction, the radially inner side region of liquid storage cylinder (301) constitutes liquid storage chamber (301M), region between the radially inner side of the periphery wall of the radial outside and detection container (300) of liquid storage cylinder (301) constitutes test chamber (301N), after sampling component is installed to detection container (300), body (200) are sampled to be squeezed by liquid storage cylinder (301) and discharge absorbed saliva sample, make Part saliva sample enters liquid storage chamber (301M), part saliva sample enters test chamber (301N).Saliva collection apparatus according to the present invention is capable of providing test samples twice by one acquisition process, realizes the function of liquid storage and reinspection.
Description
Technical field
The present invention relates to in-vitro diagnosis fields, more particularly, to a kind of saliva collection apparatus.
Background technique
Saliva collection apparatus in the prior art is usually disposable, can only correspond to completion one after acquiring a saliva
The detection of secondary saliva sample.And in actual operation, when such as needing to detect subject and whether consume illegal drugs, when sample for the first time
When testing result is positive, it usually needs rechecked the accuracy to guarantee testing result to sample.Therefore above-mentioned primary
The saliva collection apparatus for acquiring corresponding one-time detection is not able to satisfy reinspection demand.
In addition, saliva collection apparatus in the prior art tends not to prompt whether sample size collected meets demand,
Prevent subject from grasping suitable collection capacity.
Summary of the invention
It is an object of the invention to overcome or at least mitigate above-mentioned the shortcomings of the prior art, a kind of can provide again is provided
The saliva collection apparatus of sample sheet.
The present invention provides a kind of saliva collection apparatus comprising detection container and sampling component, the sampling component can
It is contained in the detection container, the sampling component includes the sampling body for absorbing saliva sample, wherein
The base wall of the detection container has through-hole, and the periphery of the through-hole, which is connected with, is contained in the detection container
The liquid storage cylinder of inner cavity, the liquid storage cylinder are perforation in the axial direction,
The radially inner side region of the liquid storage cylinder constitutes liquid storage chamber,
Region between the radial outside of the liquid storage cylinder and the radially inner side of the periphery wall of the detection container constitutes inspection
Chamber is surveyed,
The end face positioned at the detection container bottom of the liquid storage chamber can destructively be closed,
After the sampling component is installed to the detection container, the sampling body is squeezed by the liquid storage cylinder and discharges institute
The saliva sample absorbed enters the part saliva sample described in the liquid storage chamber, the part saliva sample entrance
Test chamber.
In at least one embodiment, the closure of the end face positioned at the detection container bottom of the liquid storage chamber is
Aluminium sealer.
In at least one embodiment, the outer diameter of the liquid storage cylinder is less than the outer diameter of the sampling body.
In at least one embodiment, the sampling component further includes sampling handle, and the sampling handle includes sampling
Cylinder, the sampling cylinder are located at an end in the axial direction of the sampling handle, and the sampling body is fixed on the sampling cylinder simultaneously
At least partly stretch out the sampling cylinder.
In at least one embodiment, the sampling component further includes the indicator that can change colour after soaking, the finger
Show that part is connected to the sampling body, after the sampling body absorbs the saliva sample of sufficient amount, saliva sample is transmitted to the finger
Showing makes the indicator change colour at part.
In at least one embodiment, the sampling handle further includes indicator drum, and the internal diameter of the indicator drum is less than institute
The internal diameter of sampling cylinder is stated, the inner cavity of the indicator drum is connected to the inner cavity of the sampling cylinder,
The inner cavity of the indicator drum accommodates the indicator that can change colour after wetting, and the indicator is connected to the sampling
Body.
In at least one embodiment, the sampling handle further includes locking cylinder, and the periphery wall of the locking cylinder has
The lock structure being removedly connected with the detection container.
In at least one embodiment, the sampling handle further includes handheld tube, the handheld tube and the locking cylinder
It is connected, the outer diameter of the handheld tube is greater than the outer diameter of the locking cylinder.
In at least one embodiment, described device further includes the test paper card plug of tubular, and the test paper card plug is for holding
Receive the Test paper for detecting the saliva sample,
The outer diameter of the test paper card plug is less than or equal to the internal diameter of the periphery wall of the detection container, the test paper card plug
Internal diameter is greater than the outer diameter of the liquid storage cylinder.
In at least one embodiment, the test paper card plug includes support portion, and the support portion protrudes from the test paper
The axial end face of the main body of card plug, when the test paper card plug is placed in the inner cavity of the detection container, the support portion against
To the base wall.
Saliva collection apparatus according to the present invention is capable of providing test samples twice by one acquisition process, realizes
The function of liquid storage and reinspection.
Detailed description of the invention
Fig. 1 is the decomposition diagram of the axial section view of saliva collection apparatus according to embodiment of the present invention.
Fig. 2 is the schematic diagram of the axial section view of the completion installation of the corresponding saliva collection apparatus of Fig. 1.
Description of symbols
100 sampling handles；101 sampling cylinders；102 indicator drums；103 locking cylinders；104 handheld tubes；
200 sampling bodies；
300 detection containers；301 liquid storage cylinders；301M liquid storage chamber；301N test chamber；302 base walls；
400 test paper card plugs；401 test paper slots；402 support portions；
500 sealing films；600 indicators；S sealing ring；
A is axial；R is radial.
Specific embodiment
Exemplary embodiments of the present invention are described with reference to the accompanying drawings.It should be appreciated that these specific descriptions are only used for
How teaching those skilled in the art implement the present invention, rather than all feasible modes that exhaustion is of the invention, without in
It limits the scope of the invention.
Below unless stated otherwise, referring to Fig.1, in the drawings and in the description, A indicates the axial direction of saliva collection apparatus, and R is indicated
The radial direction of saliva collection apparatus.
In the present embodiment, saliva collection apparatus includes sampling handle 100, sampling body 200, detection container 300, test paper
Card plug 400, sealing film 500, indicator 600 and sealing ring S.
Sampling handle 100, sampling body 200, indicator 600 and sealing ring S are assembled together to be participated in constituting set of samples jointly
Part.
(sampling component)
With reference first to Fig. 1, the basic structure of sampling component is introduced.
Sampling handle 100 plays the role of bracket in sampling component.Sampling handle 100 include on axial A successively
Connected sampling cylinder 101, indicator drum 102, locking cylinder 103 and handheld tube 104.
Sampling cylinder 101 has the end wall of annular and is circumferentially connected to the peripheral wall of end wall periphery in substantially cover shape.Sampling
Body 200 partly accommodates and is fixed on the inner cavity of sampling cylinder 101.
The connection type for sampling body 200 and sampling cylinder 101 is, for example, point glue sticking.Preferably, sampling body 200 is by water imbibition
Strong fiber is constituted and is compressed into cylindric.The axial length for sampling body 200 is greater than the axial length of sampling cylinder 101, thus
Sampling body 200 stretches out in sampling cylinder 101 (i.e. when sampling component is without supplying detection container 300) in its natural state,
The extension end for sampling body 200 can be placed in mouth to acquire saliva by subject.Sampling body 200 obtains after fully absorbing saliva sample
The sample size taken provides detection twice enough and uses.
Indicator drum 102 has hollow inner cavity, and the inner cavity of indicator drum 102 and the inner cavity of sampling cylinder 101 communicate.Refer to
Show that part 600 is contained in the inner cavity of indicator drum 102 and contacts with sampling body 200.
The making material of indicator 600 includes water-absorbing material, such as indicator 600 is discoloration test paper, water suction front and back
Color it is different.After sampling body 200 absorbs enough saliva samples, saliva can be further transferred to indicator 600 and quilt
It is absorbed, and indicator 600 changes colour.
Preferably, indicator drum 102 is transparent or at least has partially transparent region, is allowed an operator to through instruction
Cylinder 102 identifies the color of indicator 600.
The periphery wall of locking cylinder 103 has lock structure, which is used for and the detection container 300 that is discussed below
Internal perisporium lock structure coupling, thus realize sampling handle 100 and detection container 300 dismountable connection.Preferably,
The lock structure of the internal perisporium of the lock structure and detection container 300 of the periphery wall of locking cylinder 103 is helicitic texture.
The outer diameter of the peripheral wall of handheld tube 104 is greater than the outer diameter of the peripheral wall of locking cylinder 103.When sampling handle 100 is installed to inspection
After xylometer 300, locking cylinder 103 will be housed in the inner cavity of detection container 300 and handheld tube 104 expose detection container 300 with
The convenient dismounting to sampling handle 100.
Sealing ring S is mounted on the periphery of locking cylinder 103 and abuts to the end of handheld tube 104, when sampling handle 100 is installed
To after detection container 300, sealing ring S above while can play sealing function on axial A and circumferentially.
(saliva collection apparatus)
Sampling component and detection container 300, test paper card plug 400 and sealing film 500 together constitute saliva according to the present invention
Liquid collection apparatus.
Referring to Figures 1 and 2, detection container 300 is in the tubular of both ends open.The base wall 302 of detection container 300 is in ring
Shape, the inner peripheral portion of base wall 302 is connected with the liquid storage cylinder 301 of the inner cavity for being contained in detection container 300 of annular, thus in liquid storage
The inner circumferential side of cylinder 301 limits liquid storage chamber 301M, the shape between the peripheral side of liquid storage cylinder 301 and the inner circumferential side of detection container 300
At test chamber 301N.
The internal diameter of liquid storage cylinder 301 is less than the outer diameter of sampling body 200.Preferably, the outer diameter of liquid storage cylinder 301 is again smaller than sampling body
200 outer diameter.In sampling process to be introduced below, body 200 is sampled by the extruding on axial A by liquid storage cylinder 301
And it is compressed.
Sealing film 500 is fixed on base wall 302, in one end of the axial end portion of detection container 300 closing liquid storage cylinder 301
Opening.Sealing film 500 is, for example, aluminium sealer, such as can be connected to detection container 300 using seal technique.
Test paper card plug 400 is in the tubular of both ends open.Preferably, test paper card plug 400 can be close to 300 inner wall of detection container
Ground is placed in detection container 300.The internal diameter of test paper card plug 400 is equal or slightly larger than the outer diameter of sampling cylinder 101, and test paper card plug
400 internal diameter is greater than the outer diameter of liquid storage cylinder 301, thus sampling body 200 be squeezed and after deforming and releasing part saliva sample,
These saliva samples can flow into test chamber 301N.
The periphery wall of test paper card plug 400 limits multiple for storing the test paper slot 401 of Test paper.Test paper card plug 400
Main body axial one end axially projectingly be equipped with several support portions 402, in other words, an end of test paper card plug 400 is in axis
It is not concordant upwards.Test paper card plug 400 is placed in detection container 300 in a manner of inwardly by support portion 402, support portion 402
The bottom end face of test chamber 301N will be abutted to, and test chamber 301N has the area that do not filled up by test card plug 400 in the circumferential
Domain, these regions provide the flowing space for saliva sample.
Next it introduces and is sampled and rechecked the method for taking liquid using saliva collection apparatus according to the present invention.
Subject uses sampling component to obtain saliva sample first, after the discoloration of part 600 to be instructed is to prompt sampling quantity enough,
The insertion of handle 100 will be sampled equipped in the detection container 300 of test paper card plug 400.When the completion of sampling handle 100 and detection container
After 300 installation, i.e. after the internal screw thread of the external screw thread of locking cylinder 103 and detection container 300 screws togather completely, sampling body 200 is stored up
Fluid cylinder 301 squeezes, and part saliva sample is flowed into liquid storage chamber 301M and is temporarily stored, and part saliva sample flows into test chamber 301N
It is interior and further contact test paper card plug 400 in Test paper and obtain for the first time detect.
When needing to recheck the saliva sample stored in liquid storage chamber 301M, sealing film 500 can be punctured, liquid storage is made
Saliva sample outflow in chamber 301M.
An advantage during the present invention has at least the following advantages:
(i) saliva collection apparatus of the invention by one acquisition to saliva sample be separately stored in liquid storage chamber 301M and inspection
It surveys in chamber 301N, one acquisition is enabled to provide the sample of saliva detection twice.
(ii) color change for passing through indicator 600, simply and significantly indicates whether sampling quantity meets the requirements, and improves
The efficiency of sampling process.
(iii) by destroying the sealing acquisition reinspection of film 500 required saliva sample when, sampling process is simple and sample is used in reinspection
Originally it is not easy maliciously to be exchanged.
Certainly, the present invention is not limited to the above embodiments, and those skilled in the art under the teachings of the present invention can be to this
The above embodiment of invention makes various modifications, without departing from the scope of the present invention.Such as:
Indicator 600, which may not be, to be contained in indicator drum 102, for example, indicator 600 can be attached directly to sampling
The periphery of body 200 and the close sampling cylinder 101 on axial A.
Claims (10)
1. a kind of saliva collection apparatus comprising detection container (300) and sampling component, the sampling component can be contained in institute
It states in detection container (300), the sampling component includes the sampling body (200) for absorbing saliva sample, which is characterized in that
The base wall (302) of the detection container (300) has through-hole, and the periphery of the through-hole, which is connected with, is contained in the detection
The liquid storage cylinder (301) of the inner cavity of container (300), the liquid storage cylinder (301) are perforation in the axial direction,
The radially inner side region of the liquid storage cylinder (301) constitutes liquid storage chamber (301M),
Region between the radially inner side of the periphery wall of the radial outside and detection container (300) of the liquid storage cylinder (301)
It constitutes test chamber (301N),
The end face positioned at the detection container (300) bottom of the liquid storage chamber (301M) can destructively be closed,
After the sampling component is installed to the detection container (300), the sampling body (200) is by the liquid storage cylinder (301)
It squeezes and discharges the saliva sample absorbed, the part saliva sample is made to enter the liquid storage chamber (301M), part institute
Saliva sample is stated into the test chamber (301N).
2. saliva collection apparatus according to claim 1, which is characterized in that the liquid storage chamber (301M) is located at the inspection
The closure of the end face of xylometer (300) bottom is aluminium sealer.
3. saliva collection apparatus according to claim 1, which is characterized in that the outer diameter of the liquid storage cylinder (301) is less than institute
State the outer diameter of sampling body (200).
4. saliva collection apparatus according to claim 1, which is characterized in that the sampling component further includes sampling handle
(100), the sampling handle (100) includes sampling cylinder (101), and the sampling cylinder (101) is located at sampling handle (100)
An end in axial direction, the sampling body (200) are fixed on the sampling cylinder (101) and at least partly stretch out the sampling
Cylinder (101).
5. saliva collection apparatus according to claim 1, which is characterized in that the sampling component further includes can after soaking
The indicator (600) of discoloration, the indicator (600) are connected to the sampling body (200), when the sampling body (200) absorbs
After the saliva sample of sufficient amount, saliva sample, which is transmitted at the indicator (600), makes the indicator (600) to change colour.
6. saliva collection apparatus according to claim 4, which is characterized in that the sampling handle (100) further includes instruction
Cylinder (102), the internal diameter of the indicator drum (102) are less than the internal diameter of the sampling cylinder (101), the inner cavity of the indicator drum (102)
It is connected to the inner cavity of the sampling cylinder (101),
The inner cavity of the indicator drum (102) accommodates the indicator (600) that can change colour after wetting, and the indicator (600) is even
It is connected to the sampling body (200).
7. saliva collection apparatus according to claim 4, which is characterized in that the sampling handle (100) further includes locking
Cylinder (103), the periphery wall of the locking cylinder (103) have the lock structure being removedly connected with the detection container (300).
8. saliva collection apparatus according to claim 7, which is characterized in that the sampling handle (100) further includes holding
Cylinder (104), the handheld tube (104) are connected with the locking cylinder (103), and the outer diameter of the handheld tube (104) is greater than the lock
Close the outer diameter of cylinder (103).
9. saliva collection apparatus according to claim 1, which is characterized in that described device further includes the test paper card plug of tubular
(400), the test paper card plug (400) is used to accommodate the Test paper for detecting the saliva sample,
The outer diameter of the test paper card plug (400) is less than or equal to the internal diameter of the periphery wall of the detection container (300), the test paper
The internal diameter of card plug (400) is greater than the outer diameter of the liquid storage cylinder (301).
10. saliva collection apparatus according to claim 9, which is characterized in that the test paper card plug (400) includes support portion
(402), the support portion (402) protrudes from the axial end face of the main body of the test paper card plug (400), when the test paper card plug
(400) when being placed in the inner cavity of the detection container (300), the support portion (402) abuts to the base wall (302).
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910468084.4A CN110074823A (en) | 2019-05-31 | 2019-05-31 | Saliva collection apparatus |
| PCT/CN2019/116287 WO2020238035A1 (en) | 2019-05-31 | 2019-11-07 | Saliva sampling and testing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910468084.4A CN110074823A (en) | 2019-05-31 | 2019-05-31 | Saliva collection apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110074823A true CN110074823A (en) | 2019-08-02 |
Family
ID=67422899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910468084.4A Pending CN110074823A (en) | 2019-05-31 | 2019-05-31 | Saliva collection apparatus |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN110074823A (en) |
| WO (1) | WO2020238035A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111380724A (en) * | 2020-04-24 | 2020-07-07 | 万华普曼生物工程有限公司 | Body fluid sample collecting and inspecting device |
| WO2020238035A1 (en) * | 2019-05-31 | 2020-12-03 | 万华普曼生物工程有限公司 | Saliva sampling and testing device |
| CN116793429A (en) * | 2023-07-27 | 2023-09-22 | 北京华铠安全防护技术有限公司 | Dangerous goods detector integrating explosive drug detection and dangerous liquid detection |
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| EP4173711A1 (en) | 2021-10-27 | 2023-05-03 | Société BIC | Device for collecting biological samples |
| EP4173707A1 (en) | 2021-10-27 | 2023-05-03 | BIC Violex Single Member S.A. | Device for collecting biological samples |
| EP4173713A1 (en) | 2021-10-27 | 2023-05-03 | BIC Violex Single Member S.A. | Device for collecting biological samples |
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| EP4173710A1 (en) | 2021-10-27 | 2023-05-03 | BIC Violex Single Member S.A. | Device for collecting biological samples |
| WO2023073032A1 (en) | 2021-10-27 | 2023-05-04 | Societe Bic | Device for collecting biological samples |
| EP4173712A1 (en) | 2021-10-27 | 2023-05-03 | Société BIC | Device for collecting biological samples |
| CN117462180B (en) * | 2023-12-27 | 2024-03-12 | 中国人民解放军总医院第二医学中心 | Saliva sampling screening device |
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| CN111380724B (en) * | 2020-04-24 | 2023-08-25 | 万华普曼生物工程有限公司 | Body fluid sample sampling and detecting device |
| CN116793429A (en) * | 2023-07-27 | 2023-09-22 | 北京华铠安全防护技术有限公司 | Dangerous goods detector integrating explosive drug detection and dangerous liquid detection |
| CN116793429B (en) * | 2023-07-27 | 2023-11-14 | 北京华铠安全防护技术有限公司 | Dangerous goods detector integrating explosive drug detection and dangerous liquid detection |
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| WO2020238035A1 (en) | 2020-12-03 |
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