CN110064130A - A kind of gall-bladder pacemaker - Google Patents
A kind of gall-bladder pacemaker Download PDFInfo
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- CN110064130A CN110064130A CN201910307213.1A CN201910307213A CN110064130A CN 110064130 A CN110064130 A CN 110064130A CN 201910307213 A CN201910307213 A CN 201910307213A CN 110064130 A CN110064130 A CN 110064130A
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- Prior art keywords
- module
- gall
- bladder
- external controller
- internal stimulator
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- 210000000232 gallbladder Anatomy 0.000 title claims abstract description 64
- 230000000638 stimulation Effects 0.000 claims abstract description 31
- 238000001514 detection method Methods 0.000 claims abstract description 6
- 238000002513 implantation Methods 0.000 claims abstract description 3
- 230000004936 stimulating effect Effects 0.000 claims description 21
- 238000000034 method Methods 0.000 claims description 12
- 230000008569 process Effects 0.000 claims description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 210000003205 muscle Anatomy 0.000 claims description 3
- 239000000741 silica gel Substances 0.000 claims description 3
- 229910002027 silica gel Inorganic materials 0.000 claims description 3
- 230000003187 abdominal effect Effects 0.000 claims description 2
- 230000005611 electricity Effects 0.000 claims description 2
- 239000004973 liquid crystal related substance Substances 0.000 claims 1
- 208000004845 Cholecystolithiasis Diseases 0.000 abstract description 7
- 201000001883 cholelithiasis Diseases 0.000 abstract description 7
- 201000001352 cholecystitis Diseases 0.000 abstract description 5
- 208000035965 Postoperative Complications Diseases 0.000 abstract description 3
- 230000001737 promoting effect Effects 0.000 abstract 1
- 238000005424 photoluminescence Methods 0.000 description 7
- 238000010586 diagram Methods 0.000 description 5
- 238000011282 treatment Methods 0.000 description 5
- 230000008602 contraction Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000033764 rhythmic process Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 210000000941 bile Anatomy 0.000 description 2
- 210000000013 bile duct Anatomy 0.000 description 2
- 230000002051 biphasic effect Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 231100000017 mucous membrane irritation Toxicity 0.000 description 2
- 230000000661 pacemaking effect Effects 0.000 description 2
- 210000002460 smooth muscle Anatomy 0.000 description 2
- 230000000392 somatic effect Effects 0.000 description 2
- 239000004575 stone Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000007238 Postcholecystectomy Syndrome Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229940124571 cholagogue Drugs 0.000 description 1
- 238000002192 cholecystectomy Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000001198 duodenum Anatomy 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003183 myoelectrical effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000011369 optimal treatment Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 239000007784 solid electrolyte Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0507—Electrodes for the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
Landscapes
- Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Electrotherapy Devices (AREA)
Abstract
The invention discloses a kind of gall-bladder pacemakers, including internal stimulator, external controller and the end PC；The end PC is connect with the external controller serial ports, is used to for pre-set control instruction parameter being transmitted in the external controller；The external controller and the internal stimulator are instructed, while being used for the storage and display of vivo detection data using wirelessly communicating for the internal stimulator input control；In the internal stimulator implantation patient, certain electric current stimulation is provided for sufferer gall-bladder.Gall-bladder pacemaker provided by the present invention has the function that stimulation is shunk by carrying out electric current stimulation to gallbladder wall, it is realized with this and cholecystolithiasis is treated, avoid the postoperative complications as brought by excision treating cholecystitis mode, new approach is provided for treating cholecystitis, with more vast market prospect, convenient for promoting.
Description
Technical field
The present invention relates to electron medical treatment product technical field, specially a kind of gall-bladder pacemaker.
Background technique
Cholecystolithiasis is a kind of common disease, and the disease incidence of China developed area has reached 10%-12%.Cholecystolithiasis
Treatment adopt cholecystectomy always, but the complication of postcholecystectomy has indigestion, abdominal distension, diarrhea, duodenum
The reflux of liquid and gastric juice oesophagus, postcholecystectomy syndrome, bile duct injury etc. in art, incidence in 10%-15%, and
Once bile duct injury occurs, consequence is extremely serious.
In recent years to the meaning of the research pay attention to day by day gallbladder contraction function of the cholecystolithiasis origin cause of formation, Clinical and experimental study table
Not fully dependent on the change in terms of bile physical chemistry, gall-bladder especially gallbladder contraction function itself hinders for the formation of bright cholelith
Hinder and plays an important role in the formation of cholesterol stone.However at present both at home and abroad in treatment gallbladder contraction function obstacle side
Face, in addition to some cholagogues, dissolve stone Chinese medicine other than, clinician is helpless.
Summary of the invention
The problem of for background technique, the present invention provides a kind of gall-bladder pacemakers.
To achieve the above object, the invention provides the following technical scheme: a kind of gall-bladder pacemaker, including internal stimulator,
External controller and the end PC；
The end PC is connect with the external controller serial ports, is used to transmit pre-set control instruction parameter
To in the external controller；
The external controller and the internal stimulator are the internal stimulator input control using wirelessly communicating
Instruction, while being used for the storage and display of vivo detection data；
In the internal stimulator implantation patient, certain electric current stimulation is provided for sufferer gall-bladder.
As a preferred technical solution of the present invention, the internal stimulator includes first microprocessor, the first radio frequency
Module, the first power module, clock control module, pulse generating module and stimulating electrode, first power module, first
Radio-frequency module, clock control module and pulse generating module are electrically connected with the first microprocessor, the pulse generation
Module is connect by extension lead with the stimulating electrode.
As a preferred technical solution of the present invention, the external controller includes the second microprocessor, the second radio frequency
Module, LCD MODULE, second power supply module and input key, second radio-frequency module, LCD MODULE, second
Power module and input key are electrically connected with second microprocessor.
As a preferred technical solution of the present invention, the pulse generating module generation is overlap biphasic impulse waveform.
As a preferred technical solution of the present invention, first power module uses clang battery.
As a preferred technical solution of the present invention, the first microprocessor of the internal stimulator, the first radio frequency mould
Block, the first power module, clock control module and pulse generating module are sealed in package casing, which plants in hypogastric zone
In the skin in domain, the stimulating electrode is planted in gallbladder wall muscle layer.
As a preferred technical solution of the present invention, the package casing of the internal stimulator uses silica gel material.
Compared with prior art, the beneficial effects of the present invention are: gall-bladder pacemaker provided by the present invention passes through to gall-bladder
Wall carries out electric current stimulation to have the function that stimulation is shunk, and is realized with this and is treated to cholecystolithiasis, avoided and controlled by excision gall-bladder
Postoperative complications brought by treatment mode provide new approach for treating cholecystitis, have more vast market prospect, are convenient for
It promotes.
Detailed description of the invention
Fig. 1 is a kind of gall-bladder pacemaker overall structure diagram provided by the invention；
Fig. 2 is a kind of internal stimulator structural schematic diagram of gall-bladder pacemaker provided by the invention；
Fig. 3 is a kind of external controller structural schematic diagram of gall-bladder pacemaker provided by the invention；
Fig. 4 is a kind of internal stimulator external structure schematic diagram of gall-bladder pacemaker provided by the invention；
Fig. 5 is a kind of external controller external structure schematic diagram of gall-bladder pacemaker provided by the invention；
In figure: stimulator in 1- body；101- first microprocessor；The first radio-frequency module of 102-；The first power module of 103-；
104- clock control module；105- pulse generating module；106- stimulating electrode；107- package casing；2- external controller；201-
Second microprocessor；The second radio-frequency module of 202-；203- LCD MODULE；204- second power supply module；205- inputs key；
The end 3-PC.
Specific embodiment
The basic principle of gall-bladder pace-making is that the electrical activity based on people's gall-bladder pacemaker can stimulate institute " to drive by additional electric current
It is dynamic ", the gall-bladder bio-electrical information similar with human gall bladder basic electric rhythm generated using electronic technology selects optimal treatment
Frequency and amplitude act on gall-bladder bottom pacemaker through internal or body surface, so that gall-bladder electrical activity is generated " following effect ", can make
Gall-bladder electricity restores the normal rhythm and pace of moving things and wave amplitude and reaches pre- so that the symptom of gallbladder contraction function obstacle disease be mitigated or eliminated
Anti- and treatment cholecystolithiasis purpose.
The main points that gall-bladder pace-making needs to pay attention to are as follows: 1, according to the position of stimulating electrode: gall-bladder electrical stimulation method is divided into slurry
Film stimulation, mucosal irritation and somatic stimulation.Wherein serous coat stimulation, which refers to, manages stimulating electrode in serosa of gallbladder face and does not penetrate viscous
Film layer directly acts on the stimulating method of smooth muscle of bile vesica.Mucosal irritation refers to stimulating electrode as mucous membrane of gallbladder surface, leads to
Adsorption electrode is crossed by exogenous electro photoluminescence by mucous membrane, smooth muscle layer is reached, to control a kind of stimulating method of myoelectrical activity.
Somatic stimulation, including the stimulation of body surface pacemaker and the stimulation of body surface acupoint.The stimulation of body surface pacemaker is from gall-bladder bottom in abdomen
The projection position input stimulus signal of portion's body surface, to drive gallbladder motor.
2, the quantity of stimulating electrode；Gall-bladder electrical stimulation method is divided into single lead stimulation and multi-lead stimulation.Single lead stimulation
Refer in physiological gall-bladder pacemaker region (bottom) a pair of electrodes row gall-bladder electro photoluminescence.Multi-lead stimulation, which then refers to, to be paced
The point multipair rows of electrodes gall-bladder electro photoluminescence in region, main purpose is to imitate the propagation and characteristic of normal gall-bladder slow wave.
3, according to the frequency of electro photoluminescence, gall-bladder electrical stimulation method is divided into high frequency stimulation, low frequency stimulating and pulse train.Its
Medium-high frequency stimulation refers to the electro photoluminescence with the 2-10 times of intrinsic slow wave rhythm and pace of moving things, but its pulsewidth is mostly hundreds of microseconds.Low frequency stimulating is
Refer to the electro photoluminescence of approximate or slightly above gall-bladder the intrinsic slow wave rhythm and pace of moving things, wave mode is impulse wave, and pulsewidth is generally Millisecond.Train of pulse
Stimulation is by duplicate burst blocks at being the combination based on two kinds of stimulation modes of low frequency stimulating and high frequency stimulation.
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, the present invention provides a kind of gall-bladder pacemaker, including internal stimulator 1, external controller 2 and PC
End 3；
The end PC 3 is connect with 2 serial ports of external controller, is used to pass pre-set control instruction parameter
It transports in the external controller 2；
The external controller 2, using wirelessly communicating, is inputted with the internal stimulator 1 for the internal stimulator 1
Control instruction, while being used for the storage and display of vivo detection data；
The internal stimulator 1 is implanted into patient, and certain electric current stimulation is provided for sufferer gall-bladder.
As shown in Fig. 2 and Fig. 4, the internal stimulator 1 includes first microprocessor 101, the first radio-frequency module 102, the
One power module 103, clock control module 104, pulse generating module 105 and stimulating electrode 106, first power module
103, the first radio-frequency module 102, clock control module 104 and pulse generating module 105 with the first microprocessor 101
Electrical connection, the pulse generating module 105 are connect by extension lead with the stimulating electrode 106.
As shown in Fig. 3 and Fig. 5, the external controller 2 includes the second microprocessor 201, the second radio-frequency module 202, liquid
Brilliant display module 203, second power supply module 204 and input key 205, second radio-frequency module 202, LCD MODULE
203, second power supply module 204 and input key 205 are electrically connected with second microprocessor 201.
The present invention at work, is connect by the software at the end PC 3 with 2 serial ports of external controller, by pre-set control
Order parameter processed downloads in external controller 2, then transmits control signals to internal stimulator 1, body by less radio-frequency
Internal stimulus device 1 generates corresponding actions after receiving command signal, acts on gall-bladder bottom smooth muscle cell through stimulating electrode 106, real
Existing gallbladder wall electro photoluminescence.Command signal, which mainly has, to be started stimulation, terminates stimulation, start detection, terminate detection, current detecting, be
System suspend mode and system reset etc..
In the specific implementation process, it is acted directly in biological tissue due to boost pulse by stimulating electrode, Ji Yaokao
Consider effect of stimulation, and need to consider its biological safety, selection endangers the smallest stimulus waveform to biological tissue.The present inventor grinds
It is all minimum to electrode corrosion and tissue damage to study carefully discovery overlap biphasic impulse waveform, thus is selected as body of gallbladder internal stimulus pulse
Basic waveform.Stimulus modality selects biological safety higher, and the constant pressure stimulus modality of comparative maturity is as cardinal stimuli mode.
In the specific implementation process, the use of the first power module 103 clang battery, clang battery applications solid electrolyte,
Can be hermetically sealed, energy height, high reliablity, self discharge amount are small.Clang ion charging battery with its high working voltage, the high circulation service life and
The excellent properties such as high-energy density are considered as the best battery system of current comprehensive performance.This gall-bladder pacemaker uses the time 2
Year, 3 times a day, 30 minutes every time.This active battery projected life is 5 years, fully meets needs.
As shown in figure 4, in the specific implementation process, first microprocessor 101, the first radio frequency of the internal stimulator 1
Module 102, the first power module 103, clock control module 104 and pulse generating module 105 are sealed in package casing 107
In, which plants in the skin of lower abdominal region, and the stimulating electrode 106 is planted in gallbladder wall muscle layer.
In the specific implementation process, the body of gallbladder internal stimulus device as designed by inventor is implanted therapeutic device,
Biocompatibility issues are also the problem of must be taken into consideration.In view of the rejection that egersimeter can generate in implanted body of gallbladder is anti-
It answers, the present invention is preferable using biocompatibility, encapsulation of nontoxic, the harmless medical safe silica gel material as internal stimulator
Shell 107.
Based on above-mentioned, present invention has the advantage that: gall-bladder pacemaker provided by the present invention by gallbladder wall into
The stimulation of row electric current is shunk to have the function that stimulate, and is realized with this and is treated to cholecystolithiasis, avoided by excision treating cholecystitis side
Postoperative complications brought by formula provide new approach for treating cholecystitis, have more vast market prospect, convenient for pushing away
Extensively.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (7)
1. a kind of gall-bladder pacemaker, it is characterised in that: including internal stimulator, external controller and the end PC；
The end PC is connect with the external controller serial ports, is used to pre-set control instruction parameter being transmitted to institute
It states in external controller；
The external controller and the internal stimulator are referred to using wirelessly communicating for the internal stimulator input control
It enables, while being used for the storage and display of vivo detection data；
In the internal stimulator implantation patient, certain electric current stimulation is provided for sufferer gall-bladder.
2. a kind of gall-bladder pacemaker according to claim 1, it is characterised in that: the internal stimulator includes first micro- place
Reason device, the first radio-frequency module, the first power module, clock control module, pulse generating module and stimulating electrode, described first
Power module, the first radio-frequency module, clock control module and pulse generating module are electrically connected with the first microprocessor,
The pulse generating module is connect by extension lead with the stimulating electrode.
3. a kind of gall-bladder pacemaker according to claim 2, it is characterised in that: the external controller includes second micro- place
Manage device, the second radio-frequency module, LCD MODULE, second power supply module and input key, second radio-frequency module, liquid crystal
Display module, second power supply module and input key are electrically connected with second microprocessor.
4. a kind of gall-bladder pacemaker according to claim 2, it is characterised in that: the pulse generating module generation is double
Phase stimulus waveform.
5. a kind of gall-bladder pacemaker according to claim 2, it is characterised in that: first power module is using clang electricity
Pond.
6. a kind of gall-bladder pacemaker according to claim 2, it is characterised in that: the first micro process of the internal stimulator
Device, the first radio-frequency module, the first power module, clock control module and pulse generating module are sealed in package casing, should
Part is planted in the skin of lower abdominal region, and the stimulating electrode is planted in gallbladder wall muscle layer.
7. a kind of gall-bladder pacemaker according to claim 6, it is characterised in that: the package casing of the internal stimulator is adopted
Use silica gel material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910307213.1A CN110064130A (en) | 2019-04-17 | 2019-04-17 | A kind of gall-bladder pacemaker |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910307213.1A CN110064130A (en) | 2019-04-17 | 2019-04-17 | A kind of gall-bladder pacemaker |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110064130A true CN110064130A (en) | 2019-07-30 |
Family
ID=67367883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910307213.1A Pending CN110064130A (en) | 2019-04-17 | 2019-04-17 | A kind of gall-bladder pacemaker |
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| Country | Link |
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Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056432A (en) * | 1990-05-11 | 1991-11-27 | 袁效果 | Ultra-low-frequency electrotherapy instrument for cholelithiasis |
| CN1476339A (en) * | 2000-09-26 | 2004-02-18 | 特兰施钮罗尼克斯股份有限公司 | Method and apparatus for treating obesity by electrical stimulation of gastrointestinal tract using sensed activity |
| US20080086180A1 (en) * | 2006-10-05 | 2008-04-10 | Omry Ben-Ezra | Techniques for gall bladder stimulation |
| CN101234227A (en) * | 2007-12-28 | 2008-08-06 | 中国人民解放军第三军医大学野战外科研究所 | Implantation type wireless limbs sport control nerve stimulation network system and control method |
| US20080195171A1 (en) * | 2007-02-13 | 2008-08-14 | Sharma Virender K | Method and Apparatus for Electrical Stimulation of the Pancreatico-Biliary System |
| CN102056645A (en) * | 2008-04-04 | 2011-05-11 | 安特罗麦迪克斯公司 | Methods and systems for glucose regulation |
| CN102500057A (en) * | 2011-09-28 | 2012-06-20 | 上海交通大学 | Multifunctional implanted gastrointestinal electrical stimulation system |
| CN104096313A (en) * | 2014-06-17 | 2014-10-15 | 华中科技大学 | Implantable nerve electrical stimulation device and system |
| CN104147699A (en) * | 2014-07-31 | 2014-11-19 | 李军 | Solar plexus electrical stimulation system used for treating type 2 diabetes mellitus |
| CN210992605U (en) * | 2019-04-17 | 2020-07-14 | 上海黎欧生物科技有限公司 | Gallbladder pacemaker |
-
2019
- 2019-04-17 CN CN201910307213.1A patent/CN110064130A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056432A (en) * | 1990-05-11 | 1991-11-27 | 袁效果 | Ultra-low-frequency electrotherapy instrument for cholelithiasis |
| CN1476339A (en) * | 2000-09-26 | 2004-02-18 | 特兰施钮罗尼克斯股份有限公司 | Method and apparatus for treating obesity by electrical stimulation of gastrointestinal tract using sensed activity |
| US20080086180A1 (en) * | 2006-10-05 | 2008-04-10 | Omry Ben-Ezra | Techniques for gall bladder stimulation |
| US20080195171A1 (en) * | 2007-02-13 | 2008-08-14 | Sharma Virender K | Method and Apparatus for Electrical Stimulation of the Pancreatico-Biliary System |
| CN101234227A (en) * | 2007-12-28 | 2008-08-06 | 中国人民解放军第三军医大学野战外科研究所 | Implantation type wireless limbs sport control nerve stimulation network system and control method |
| CN102056645A (en) * | 2008-04-04 | 2011-05-11 | 安特罗麦迪克斯公司 | Methods and systems for glucose regulation |
| CN102500057A (en) * | 2011-09-28 | 2012-06-20 | 上海交通大学 | Multifunctional implanted gastrointestinal electrical stimulation system |
| CN104096313A (en) * | 2014-06-17 | 2014-10-15 | 华中科技大学 | Implantable nerve electrical stimulation device and system |
| CN104147699A (en) * | 2014-07-31 | 2014-11-19 | 李军 | Solar plexus electrical stimulation system used for treating type 2 diabetes mellitus |
| CN210992605U (en) * | 2019-04-17 | 2020-07-14 | 上海黎欧生物科技有限公司 | Gallbladder pacemaker |
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