CN110063341A - A kind of culicifuge - Google Patents
A kind of culicifuge Download PDFInfo
- Publication number
- CN110063341A CN110063341A CN201910476336.8A CN201910476336A CN110063341A CN 110063341 A CN110063341 A CN 110063341A CN 201910476336 A CN201910476336 A CN 201910476336A CN 110063341 A CN110063341 A CN 110063341A
- Authority
- CN
- China
- Prior art keywords
- parts
- culicifuge
- citral
- emulsifier
- mosquito
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/28—Myrtaceae [Myrtle family], e.g. teatree or clove
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Botany (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to daily-use chemical industry technical fields, and in particular to a kind of culicifuge.Using the citral of extracted form natural plant as principle active component, formula is simple at low cost, and repelling effect is significant, stability is good, is applied to after human body salubrious not sticky, and there are also citrus scenteds, without any side effects, the specific groups such as pregnant woman and infant can use safely.
Description
Technical field
The invention belongs to daily-use chemical industry technical fields, and in particular to a kind of culicifuge.
Background technique
The insects such as mosquito bring to human and animal creates disturbances to, injures and life threat, can also cause such as: influence sleep,
It spreads the disease, welding, causes the poor harvest of crops.Therefore, the mankind resist the harm of insect bring using various method classes.
Commonly resisting method has chemical mosquito repellent and physics to keep away mosquito.Chemical mosquito repellent, for example use mosquito-repellent incense, electric mat, prevent
Mosquito liquid, mosquitocide aerosol etc., principle are to play mosquito repellent by chemical components such as addition Metadelphene, pyrethrins, cypermethrins
The effect of desinsection, but such method use can often bring toxicity problem, containing the ingredient being harmful to the human body, especially to pregnant woman,
The specific groups such as infant, there are poisoning hidden danger.And when using such method, the problem of also causing in terms of environmental protection.Object
Reason keeps away mosquito, such as can effectively be resisted mosquito using the methods of mosquito net, mosquito repelling lamp and is created disturbances to, also without chemicals, but mosquito net
Using trouble, and the air circulation in mosquito net is stale slowly, mosquito repelling lamp uses the limited time in night, and vulnerable to other light sources shadow
It rings, to interfere repelling effect.
In addition, most of market chemistry culicifuge is nozzle types, this seed type in certain enclosure space more suitable for driving
Mosquito, when having wind or space is excessive, volatile and usage amount is excessive, causes to waste and cannot be guaranteed effect；There is minority
Type culicifuge can be made ballpoint type, and when use is applied on body, it is this it is most of is lotion or more sticky liquid
Body, protection timeliness is short, product excessively oiliness, stick greasy, sensory experience is poor, and can usually cannot be guaranteed with flavour of a drug, safety.
Furthermore most of culicifuge in the prior art formula is complicated, and raw material type even can reach tens of kinds, and effective component is a variety of more
Sample, inventor's discovery not only cannot be guaranteed can there is stability problem between effect superposition or even heterogeneity so sometimes, make to drive
Mosquito agent product quality cannot obtain long-term guarantee.
Summary of the invention
In order to overcome the drawbacks of the prior art, a kind of culicifuge is inventor provided, with the citral of extracted form natural plant
As principle active component, formula is simple at low cost, and repelling effect is significant, and stability is good, does not glue clearly after being applied to human body
Greasy, there are also citrus scenteds, without any side effects, and the specific groups such as pregnant woman and infant can use safely.
The technical solution of the present invention is as follows:
A kind of culicifuge, raw material is according to weight, comprising: and 2-15 parts of citral, 3-15 parts of eucalyptus citriodora oil, emulsification
10-30 parts of agent, 10-25 parts of ethyl alcohol, 0.1-15 parts of sodium carboxymethylcellulose, 29-73 parts of distilled water；
Preferably, raw material is according to weight, comprising: and 3-11 parts of citral, 4-11 parts of eucalyptus citriodora oil, emulsifier
11-27 parts, 12-22 parts of ethyl alcohol, 0.1-12 parts of sodium carboxymethylcellulose, 46-68 parts of distilled water.
Preferably, emulsifier is selected from TX-10, NP-10, OP-10, AEO-9；
Preferably, emulsifier is selected from TX-10；
Preparation method are as follows: mix citral, eucalyptus citriodora oil, ethyl alcohol；Sodium carboxymethylcellulose, water, emulsifier is added,
It is stirred.
Culicifuge of the invention is more suitable for ballpoint type container.
The invention has the benefit that being prepared using Pure natural plant essential oil and the chemical products science that has no toxic side effect, nothing
Any additive, can effectively expelling parasite be up to 10 hours or so, product is colourless transparent liquid, have citrus scented, to skin without
The advantages that stimulation, while will not be detrimental to health, and outgoing carry is suitble to use, and production method is simple, and raw material easily take.
Specific embodiment
Invention is described further combined with specific embodiments below, those skilled in the art can be made to further understand
The present invention, but not as the limitation to summary of the invention, all technologies based on principle of the present invention all belong to the scope of the present invention.
Embodiment 1
The raw material and proportion of the culicifuge are by weight are as follows: and 3 parts of citral, 4 parts of eucalyptus citriodora oil, emulsifier (AEO-9) 11
Part, 12 parts of ethyl alcohol, 2 parts of sodium carboxymethylcellulose, 68 parts of distilled water.Citral, eucalyptus citriodora oil, ethyl alcohol are mixed；Carboxylic first is added
Base sodium cellulosate, water, emulsifier, are stirred.Prepare it is rear canned in conventional vessel, the container can be conventional bottle, spray
Mist bottle, ballpoint bottle etc., it is especially best with ballpoint bottle effect.
Embodiment 2
The raw material and proportion of the culicifuge are by weight are as follows: and 6 parts of citral, 7 parts of eucalyptus citriodora oil, emulsifier (OP-10) 18
Part, 15 parts of ethyl alcohol, 6 parts of sodium carboxymethylcellulose, 48 parts of distilled water.Citral, eucalyptus citriodora oil, ethyl alcohol are mixed；Carboxylic first is added
Base sodium cellulosate, water, emulsifier, are stirred.Prepare it is rear canned in conventional vessel, the container can be conventional bottle, spray
Mist bottle, ballpoint bottle etc., it is especially best with ballpoint bottle effect.
Embodiment 3
The raw material and proportion of the culicifuge are by weight are as follows: and 9 parts of citral, 8 parts of eucalyptus citriodora oil, emulsifier (TX-10)
14 parts, 18 parts of ethyl alcohol, 2 parts of sodium carboxymethylcellulose, 49 parts of distilled water.Citral, eucalyptus citriodora oil, ethyl alcohol are mixed；Carboxylic is added
Sodium carboxymethylcellulose pyce, water, emulsifier, are stirred.Prepare it is rear canned in conventional vessel, the container can be conventional bottle,
Spray bottle, ballpoint bottle etc., it is especially best with ballpoint bottle effect.
Embodiment 4
The raw material and proportion of the culicifuge are by weight are as follows: and 11 parts of citral, 11 parts of eucalyptus citriodora oil, emulsifier (NP-
10) 11 parts, 20 parts of ethyl alcohol, 1 part of sodium carboxymethylcellulose, 46 parts of distilled water.Citral, eucalyptus citriodora oil, ethyl alcohol are mixed；It is added
Sodium carboxymethylcellulose, water, emulsifier, are stirred.Prepare rear canned in conventional vessel, which can be commonly
Bottle, spray bottle, ballpoint bottle etc., it is especially best with ballpoint bottle effect.
Comparative example 1
The comparative example raw material and proportion are by weight are as follows:
11 parts of citral, 14 parts of emulsifier (TX-10), 18 parts of ethyl alcohol, 2 parts of sodium carboxymethylcellulose, 49 parts of distilled water；
(1) citral, ethyl alcohol are mixed；
(2) sodium carboxymethylcellulose, water, emulsifier, stirring, mixing are added into mixture obtained in step (1).Match
It makes rear canned in ballpoint container.
Comparative example 2
The comparative example raw material and proportion are by weight are as follows:
9 parts of citral, 8 parts of peppermint oil, 14 parts of emulsifier (TX-10), 18 parts of ethyl alcohol, 2 parts of sodium carboxymethylcellulose, distillation
49 parts of water；
(1) citral, peppermint oil, ethyl alcohol are mixed；
(2) sodium carboxymethylcellulose, water, emulsifier, stirring, mixing are added into mixture obtained in step (1).Match
It makes rear canned in ballpoint container.
Efficacy validation is carried out to the embodiment of the present invention below:
1, repelling effect is tested
(1) laboratory sample: the embodiment of the present invention 1~4,1~2 culicifuge of comparative example, certain commercially available mosquito-repellent perfume；
(2) for test worm kind and strain: aedes albopictus (Aedes albopictus), the sensitive strain standard of laboratory rearing
Test worm, -5 days 3 days female insects that do not suck blood after emergence.
(3) test method: according to GB/T 13917.9-2009 (" agriculture chemical registration hygienic insecticide indoor pharmacodynamic test and
Evaluate the 9th part: repellant ") test method tested, wherein every group of repellency test selection 20 attack is qualified
Volunteer tests, and men and women is fifty-fifty.
(4) experimental result: effective protecting time of the sample to volunteer
| Sample | Average effective guard time (h) |
| Embodiment 1 | 8.5 |
| Embodiment 2 | 9 |
| Embodiment 3 | 10 |
| Embodiment 4 | 9.5 |
| Comparative example 1 | 6 |
| Comparative example 2 | 6.5 |
| Certain commercially available mosquito-repellent perfume | 7 |
By above-mentioned experimental result it is found that inventive formulation culicifuge repelling effect is significant, when to the effective protection of volunteer
Between be up to 8h or more, repelling effect be better than comparative example and commercial product.Compared with the embodiment of the present invention 3, the formula of comparative example 1 is improved
The dosage of citral but do not add eucalyptus citriodora oil, comparative example 2 is formulated the peppermint oil similar in effect and replaces the embodiment of the present invention 3
Eucalyptus citriodora oil in formula, comparative example 1 and comparative example 2 substantially reduce the effective protecting time of volunteer, and repelling effect is not so good as
The embodiment of the present invention 3 illustrates each ingredient synergistic effect of culicifuge of the present invention, has significant repelling effect, wherein the present invention is real
It is the most significant to apply culicifuge repelling effect made from example 3.
2, safety evaluatio
(1) skin irritation test: the subject in above-mentioned mosquito repellent test is nonirritant during the test, also has no
There are whole body or local adverse reaction.
(2) skin allergy test: selection 60 people of healthy women volunteer, age between 18-40 years old, are divided into 6 groups,
Every group of 10 people, routinely usage amount after an embodiment 1-4 daily using being tested, and the period is one month, knot
Fruit proves the present invention to human skin without sensitization.
(3) acute eye irritation test: carrying out family small white mouse animal experiment according to the pertinent regulations of state, as a result proves that the present invention is real
It is non-stimulated to eyes to apply a 1-4.
3, organoleptic test is carried out according to QB/T 2660-2004
It materialses in 25mL colorimetric cylinder, visual observations are under room temperature and non-Yanguan Pass direct projection to detect appearance.
Equivalent sample and regulation sample are individually placed in identical container, with wide 0.5cm~1.0cm, long 10cm~
The blotting paper of 15cm dips sample and regulation sample about 1cm~2cm (the two should approach) as fragrant paper is commented respectively, with smell come
Identify.
Experimental result is as follows:
4, comfort is tested
Laboratory sample: the embodiment of the present invention 1~4, certain commercially available mosquito-repellent perfume
Experimental method: 60 healthy volunteers of selection participate in activity on probation, men and women each 30, the age 18-30 years old it
Between, the embodiment of the present invention 1~4, certain commercially available mosquito-repellent perfume are tested respectively.
Product sample is used respectively, and comfort evaluation result is recorded.
Experimental result is as follows:
In conclusion illustrating that culicifuge security performance of the invention is splendid, repelling effect and sense organ by comparison and experiment
Experience is also significantly better than the similar-type products of the prior art, therefore culicifuge of the invention is suitble to the use of daily indoor and outdoor.
Claims (5)
1. a kind of culicifuge, which is characterized in that its raw material is according to weight, comprising: 2-15 parts of citral, eucalyptus citriodora oil 3-
15 parts, 10-30 parts of emulsifier, 10-25 parts of ethyl alcohol, 0.1-15 parts of sodium carboxymethylcellulose, 29-73 parts of distilled water.
2. culicifuge according to claim 1, which is characterized in that its raw material is according to weight, comprising: citral 3-
11 parts, 4-11 parts of eucalyptus citriodora oil, 11-27 parts of emulsifier, 12-22 parts of ethyl alcohol, 0.1-12 parts of sodium carboxymethylcellulose, distilled water
46-68 parts.
3. culicifuge according to claim 1 or 2, which is characterized in that emulsifier be selected from TX-10, NP-10, OP-10,
AEO-9。
4. culicifuge according to claim 1 or 2, which is characterized in that emulsifier is selected from TX-10.
5. the preparation method of culicifuge according to claim 1 or 2, which is characterized in that by citral, eucalyptus citriodora oil, second
Alcohol mixing；Sodium carboxymethylcellulose, water, emulsifier is added, is stirred.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910476336.8A CN110063341A (en) | 2019-06-03 | 2019-06-03 | A kind of culicifuge |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910476336.8A CN110063341A (en) | 2019-06-03 | 2019-06-03 | A kind of culicifuge |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110063341A true CN110063341A (en) | 2019-07-30 |
Family
ID=67372388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910476336.8A Pending CN110063341A (en) | 2019-06-03 | 2019-06-03 | A kind of culicifuge |
Country Status (1)
| Country | Link |
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| CN (1) | CN110063341A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1362017A (en) * | 2000-12-30 | 2002-08-07 | 王学礼 | Mosquito repellent product and its production method |
| CN103690449A (en) * | 2013-12-17 | 2014-04-02 | 天津商业大学 | Alcohol-free mosquito-repellent floral water and preparation method thereof |
| CN105494329A (en) * | 2015-12-16 | 2016-04-20 | 西安德立生物化工有限公司 | Preparation method and application of water-soluble insect-resistant and mosquito-repellent plant oil |
| CN105519597A (en) * | 2016-01-11 | 2016-04-27 | 安佑生物科技集团股份有限公司 | Animal barn air disinfectant containing plant essential oil, and application method thereof |
| CN105534871A (en) * | 2016-02-17 | 2016-05-04 | 广西大学 | Mosquito-repelling and itching-relieving floral water and preparation method thereof |
| WO2018122034A1 (en) * | 2016-12-28 | 2018-07-05 | Zobele Holding S.P.A. | Insect repellent product |
-
2019
- 2019-06-03 CN CN201910476336.8A patent/CN110063341A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1362017A (en) * | 2000-12-30 | 2002-08-07 | 王学礼 | Mosquito repellent product and its production method |
| CN103690449A (en) * | 2013-12-17 | 2014-04-02 | 天津商业大学 | Alcohol-free mosquito-repellent floral water and preparation method thereof |
| CN105494329A (en) * | 2015-12-16 | 2016-04-20 | 西安德立生物化工有限公司 | Preparation method and application of water-soluble insect-resistant and mosquito-repellent plant oil |
| CN105519597A (en) * | 2016-01-11 | 2016-04-27 | 安佑生物科技集团股份有限公司 | Animal barn air disinfectant containing plant essential oil, and application method thereof |
| CN105534871A (en) * | 2016-02-17 | 2016-05-04 | 广西大学 | Mosquito-repelling and itching-relieving floral water and preparation method thereof |
| WO2018122034A1 (en) * | 2016-12-28 | 2018-07-05 | Zobele Holding S.P.A. | Insect repellent product |
Non-Patent Citations (5)
| Title |
|---|
| 《中国药物大全》编委会编: "《中国药物大全 西药卷》", 31 August 1991, 人民卫生出版社 * |
| 主编：李忠阳: "《有害生物防制技术指引》", 31 October 2015, 第二军医大学出版社 * |
| 主编：董桂蕃: "《吸血昆虫的化学防护》", 30 November 1999, 军事医学科学出版社 * |
| 本书编委会: "《新编药物实用全书（上）》", 30 September 1998, 中国中医药出版社 * |
| 董文煦 等: "《美丽圣经 升级版》", 30 April 2017, 广西师范大学出版社 * |
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Application publication date: 20190730 |