CN110057819A - A kind of electronic reading out device - Google Patents
A kind of electronic reading out device Download PDFInfo
- Publication number
- CN110057819A CN110057819A CN201910269927.8A CN201910269927A CN110057819A CN 110057819 A CN110057819 A CN 110057819A CN 201910269927 A CN201910269927 A CN 201910269927A CN 110057819 A CN110057819 A CN 110057819A
- Authority
- CN
- China
- Prior art keywords
- light
- photodetector
- notch
- testing element
- emitting component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012360 testing method Methods 0.000 claims abstract description 406
- 230000000903 blocking effect Effects 0.000 claims description 82
- 239000000126 substance Substances 0.000 claims description 25
- 238000007689 inspection Methods 0.000 claims description 13
- 238000001514 detection method Methods 0.000 abstract description 90
- 230000035945 sensitivity Effects 0.000 abstract description 6
- 238000010998 test method Methods 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 57
- 239000012491 analyte Substances 0.000 description 40
- 239000003153 chemical reaction reagent Substances 0.000 description 31
- 238000005286 illumination Methods 0.000 description 20
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 19
- 230000003287 optical effect Effects 0.000 description 18
- 239000007788 liquid Substances 0.000 description 17
- 239000003550 marker Substances 0.000 description 15
- 239000000463 material Substances 0.000 description 15
- 239000000758 substrate Substances 0.000 description 15
- 238000000034 method Methods 0.000 description 13
- 238000004458 analytical method Methods 0.000 description 9
- 238000009825 accumulation Methods 0.000 description 8
- 230000003760 hair shine Effects 0.000 description 8
- 239000000047 product Substances 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 5
- 238000002835 absorbance Methods 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 239000000123 paper Substances 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 210000002700 urine Anatomy 0.000 description 5
- 230000027455 binding Effects 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 235000013399 edible fruits Nutrition 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000035935 pregnancy Effects 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 229940123445 Tricyclic antidepressant Drugs 0.000 description 3
- 238000003556 assay Methods 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 150000003384 small molecules Chemical class 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000003029 tricyclic antidepressant agent Substances 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 2
- VAYOSLLFUXYJDT-RDTXWAMCSA-N Lysergic acid diethylamide Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N(CC)CC)C2)=C3C2=CNC3=C1 VAYOSLLFUXYJDT-RDTXWAMCSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000000020 Nitrocellulose Substances 0.000 description 2
- 239000004721 Polyphenylene oxide Substances 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 2
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 2
- 239000012472 biological sample Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000004587 chromatography analysis Methods 0.000 description 2
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000009533 lab test Methods 0.000 description 2
- 238000012125 lateral flow test Methods 0.000 description 2
- 229950002454 lysergide Drugs 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 229920001220 nitrocellulos Polymers 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000008520 organization Effects 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 229920006380 polyphenylene oxide Polymers 0.000 description 2
- 238000004886 process control Methods 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 239000010865 sewage Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 241000219357 Cactaceae Species 0.000 description 1
- 241000589876 Campylobacter Species 0.000 description 1
- 206010013654 Drug abuse Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 241001567553 Eryngium aquifolium Species 0.000 description 1
- 241000605909 Fusobacterium Species 0.000 description 1
- 206010052128 Glare Diseases 0.000 description 1
- 238000012351 Integrated analysis Methods 0.000 description 1
- 241000186779 Listeria monocytogenes Species 0.000 description 1
- 102000009151 Luteinizing Hormone Human genes 0.000 description 1
- 108010073521 Luteinizing Hormone Proteins 0.000 description 1
- JEYCTXHKTXCGPB-UHFFFAOYSA-N Methaqualone Chemical compound CC1=CC=CC=C1N1C(=O)C2=CC=CC=C2N=C1C JEYCTXHKTXCGPB-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- 108091005461 Nucleic proteins Proteins 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000256856 Vespidae Species 0.000 description 1
- 241000607598 Vibrio Species 0.000 description 1
- 239000011358 absorbing material Substances 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229940025084 amphetamine Drugs 0.000 description 1
- 239000000935 antidepressant agent Substances 0.000 description 1
- 229940005513 antidepressants Drugs 0.000 description 1
- 239000002249 anxiolytic agent Substances 0.000 description 1
- 230000000949 anxiolytic effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000000688 bacterial toxin Substances 0.000 description 1
- 229940125717 barbiturate Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 229960003920 cocaine Drugs 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000002359 drug metabolite Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007071 enzymatic hydrolysis Effects 0.000 description 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 238000013100 final test Methods 0.000 description 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 1
- 230000003325 follicular Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 230000004313 glare Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 239000005554 hypnotics and sedatives Substances 0.000 description 1
- 238000013095 identification testing Methods 0.000 description 1
- 238000005213 imbibition Methods 0.000 description 1
- 229960004801 imipramine Drugs 0.000 description 1
- BCGWQEUPMDMJNV-UHFFFAOYSA-N imipramine Chemical compound C1CC2=CC=CC=C2N(CCCN(C)C)C2=CC=CC=C21 BCGWQEUPMDMJNV-UHFFFAOYSA-N 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000003447 ipsilateral effect Effects 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 229940040129 luteinizing hormone Drugs 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 229960001252 methamphetamine Drugs 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- 229960002803 methaqualone Drugs 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- ORQBXQOJMQIAOY-UHFFFAOYSA-N nobelium Chemical compound [No] ORQBXQOJMQIAOY-UHFFFAOYSA-N 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- -1 opiate Substances 0.000 description 1
- 229940127240 opiate Drugs 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 229960005489 paracetamol Drugs 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000005622 photoelectricity Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000000088 plastic resin Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000013535 sea water Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 229920000468 styrene butadiene styrene block copolymer Polymers 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000002351 wastewater Substances 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/8483—Investigating reagent band
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
Abstract
The invention belongs to biochemistry detection fields, disclose a kind of electronic reading out device of reading testing result being used cooperatively together with testing element that is using biological immune test method.Electronic reading out device of the invention includes: at least two photodetectors, including the first photodetector and the second photodetector, for receiving the reflection light from testing element corresponding region, wherein one at least two photodetectors is isolated in independent space.The device of the invention allows the maximum possible as far as possible of the light from testing element specific region to be received by light detection, reduces interference of the uncorrelated area light to photodetector, improves the accuracy and sensitivity of detection.
Description
Technical field
The present invention relates to biochemistry detection fields, particularly, are related to a kind of test member with using biological immune test method
The electronic reading out device for the reading testing result that part is used cooperatively together.
Background technique
Currently, for detect in sample whether the device for fast detecting containing analyte be largely used to hospital or
In home diagnostic, these include one or more detection reagent items for the detection device of quick diagnosis, for example early pregnancy detects, poison
Product Misuse detection etc..These detection devices can obtain testing result at one minute, or at most ten minutes or so the time, tool
Have the advantages that easy to operate.Combine figure reading electronic device and test carrier, such as analytical test strip to detection stream
The visualization that testing result can be achieved in the concentration of analyte and/or amount in body sample is read.
US5580794 discloses a kind of disposable integrated analysis reader and lateral flow assay test-strips, utilizes reading
Optical element in device out obtains testing result by measurement reflected light.However the device have the defects that it is certain, when multiple
Light-emitting component is radiated in the corresponding region on narrow reagent strip, can not only be shone from the light of corresponding region internal reflection or transmission
It is mapped on specific one or multiple photodetectors, and photodetector may be directly entered from the light that light source issues, thus
Affect the accuracy of testing result.
US7315378 provides a kind of method for solving the problems, such as this, by being arranged between light-emitting component and photodetector
Baffle, the light to avoid light-emitting component from issuing shine directly on photodetector.But, it is still desirable to these equipment are changed
Into, particularly, when need in a test-strips simultaneously carry out multiple and different tests when, need photoelectric detector accurately to reflect
Signal intensity in institute's specific test region, and avoid the interference by other non-test region reflection lights.
The Chinese patent of Publication No. CN101650298 discloses a kind of assay readings being used together with analytical test strip
Device, the reader include one or more light sources, and the light that light source issues is incident in test-strips at least two and is spatially separated
Region, one or more photodetectors are for detecting the light issued from each of two regions of test-strips;In order to ensure
Each light source can only irradiate region corresponding in test-strips, by lighttight baffle make each light source optically every
From, and a domatic component is set to avoid the light from light source from being directly mapped to photodetector between light source and photodetector.
Test-strips are located above the reader light source, without covering photodetector, so that the volume of the reader is relatively large, and other light
The distance between source and photodetector need accurate control, apart from it is too far will lead to photodetector and can not receive test-strips reflected
Light.
The Chinese patent of Publication No. CN104730229 disclose it is a kind of to chemical examination detection test-strips be analyzed and processed
Electronic detecting device comprising one intersect the first separator and the second separator, the first separator includes light source separator
With anti-scatter separator.Multiple light sources are formed separately two groups in the position of light source by light source separator, and by the detection of test-strips
Area is distinguished with blank, and anti-scatter separator distinguishes the detection zone of test-strips with blank, and the second separator is by light source and light
Detector separates.Can prevent between blank area and detection zone in this way and between light emitter region and reception area light phase
Mutually interference.
When needs very delicately read final test knot with the signal intensity on test paper item on detection zone
It still has many problem when fruit just to need that traditional design is further improved, to improve its better performance
Summary of the invention
The present invention provides a kind of reading plotter for reading testing result, and knot is tested in the chemical examination on read test element
Fruit, the device reflected light as much as possible allowed on testing element are incident on photodetector;Particularly, it allows and comes from as far as possible
The effective reflected light for being able to reflect testing result on testing element is detected by photodetector, and avoids the influence of other veiling glares.
The first aspect of the present invention, the present invention provide a kind of electronic reading out device for reading result of laboratory test, described device packet
It includes:
At least two photodetectors, including the first photodetector and the second photodetector come from testing element for receiving
The reflection light of corresponding region, which is characterized in that one at least two photodetectors is isolated in independent sky
In.
Preferably, at least one photodetector is separated in independence by the blocking element being enclosed in around photodetector
Space in.
Preferably, having the notch for allowing the light from testing element to penetrate on the blocking element.
Preferably, test section or the position where control zone that the notch is set to corresponding testing element.
Preferably, the notch includes the first notch and/or the second notch.
Preferably, the blocking element includes the first light-blocking member for separating photodetector and light-emitting component, institute
Stating has the first notch on the first light-blocking member.
Preferably, first notch is inclined notch.
Preferably, the blocking element further comprises the second light-blocking part for separating photodetector and testing element
Part has the second notch on second light-blocking member.
Preferably, second notch is connected with the first notch.
Preferably, the blocking element further comprises light-blocking for separating the third of at least two photodetector
Component does not have notch on the third light-blocking member.
Preferably, described device further includes light-emitting component, the light-emitting component is set to the survey of corresponding testing element
Try the position where area or control zone.
Preferably, the light-emitting component at least two, do not have gear between at least two light-emitting components
Optical element.
Preferably, further including third photodetector between at least two light-emitting components.
Preferably, at least two light-emitting components and/or third photodetector linearly arrange.
Preferably, the electronic reading out device further includes lateral flow testing element, include on the testing element
Test section and control zone.
As a second aspect of the invention, the present invention provides a kind of electronic reading out device for reading result of laboratory test, the dress
It sets and includes:
First and second light-emitting components issue light and are irradiated to testing element accordingly in one or more areas;
First and second photodetectors receive the reflected light on the testing element accordingly one or more areas
Line;
Blocking element, the path of the light for guiding light-emitting component to issue and/or the light from testing element, wherein
The blocking element separates the first photodetector and the second photodetector in mutually independent space.
Preferably, having the notch for allowing the light from testing element to penetrate on the blocking element.
Preferably, test section or the position where control zone that the notch is set to corresponding testing element.
Preferably, the notch includes the first notch and/or the second notch.
Preferably, the blocking element includes the first light-blocking member for separating photodetector and light-emitting component, institute
Stating has the first notch on the first light-blocking member.
Preferably, first notch is inclined notch.
Preferably, the blocking element further comprises the second light-blocking part for separating photodetector and testing element
Part has the second notch on second light-blocking member.
Preferably, second notch is connected with the first notch.
Preferably, the blocking element further comprises the third light-blocking part for separating described two photodetectors
Part does not have notch on the third light-blocking member.
Preferably, the shared third light-blocking member of two photodetectors separates or two light inspection
Two third light-blocking members that device is separated from each other are surveyed to separate.
Preferably, two be separated from each other the third light-blocking member is in longitudinal parallel construction.
Preferably, first photodetector and the second photodetector linearly arranges.
Preferably, first light-emitting component and the second light-emitting component is respectively arranged at the test of corresponding testing element
Position where area and control zone.
Preferably, not having blocking element between first light-emitting component and the second light-emitting component.
Preferably, further including third photodetector between first light-emitting component and the second light-emitting component.
Preferably, first light-emitting component, the second light-emitting component and/or third photodetector linearly arrange.
As the third aspect of the present invention, the present invention provides a kind of method of the test result of read test element, provides
Foregoing electronic reading out device, the device include: at least two photodetectors, including the first photodetector and the inspection of the second light
Device is surveyed, for receiving the reflection light from testing element corresponding region, which is characterized in that at least two photodetectors
In one be isolated in independent space.
Method of the invention is by allowing light-emitting component to shine, after light is radiated at the corresponding region of testing element, through reflecting
It is received afterwards by photodetector, forms the electric signal that can be detected then to carry out the judgement of test result.
Preferably, at least one photodetector is separated in independence by the blocking element being enclosed in around photodetector
Space in, allow the light from testing element specific region to be able to enter photodetector.
Preferably, having the notch for allowing the light from testing element to penetrate on the blocking element, allows and carry out self-test member
The light of part specific region enters photodetector by the notch.
Preferably, test section or the position where control zone that the notch is set to corresponding testing element, allow and come from
The light of testing element test section or control zone enters photodetector by the notch.
Preferably, the notch includes the first notch and/or the second notch.
Preferably, the blocking element includes the first light-blocking member for separating photodetector and light-emitting component, institute
Stating the first frequency modulated light component allows the illumination for carrying out self-emission device to be mapped on testing element, without shining directly on photodetector, institute
Stating has the first notch on the first light-blocking member.
Preferably, first notch is inclined notch.
Preferably, the blocking element further comprises the second light-blocking part for separating photodetector and testing element
Part, second light-blocking member allows the illumination for carrying out self-emission device to be mapped to the corresponding region of testing element, without being irradiated to other
Region, or the light from testing element specific region is allowed to enter photodetector, have second to lack on second light-blocking member
Mouthful.
Preferably, second notch is connected with the first notch.
Preferably, the blocking element further comprises light-blocking for separating the third of at least two photodetector
Component does not have notch on the third light-blocking member.
Preferably, described device further includes light-emitting component, the light-emitting component is set to the survey of corresponding testing element
The position where area or control zone is tried, the illumination of light-emitting component is allowed to be mapped to the test section or control zone of testing element.
Preferably, the light-emitting component at least two, do not have gear between at least two light-emitting components
Optical element.
Preferably, further including third photodetector between at least two light-emitting components.
Preferably, at least two light-emitting components and/or third photodetector linearly arrange.
Preferably, the first light-emitting component and the second light-emitting component is allowed successively to shine, light is radiated at the survey of testing element
It tries on area and control zone, light enters the first photodetector and the second photodetector after reflection, is formed for determining detection knot
Fruit electric signal, for determining test result.
Beneficial effect:
Electronic reading out device of the invention is guided by blocking element or changes opticpath, in light-emitting component and light detection
A kind of preferable optical circuit path is provided between device, electronic reading out device of the invention is compact-sized, ensure that optical path signal
It sufficiently and efficiently uses, increases the accuracy and sensitivity of detection.Make the light from testing element test section and control zone most
Amount maximum possible is received by light detection, and reduces interference of the uncorrelated area light to photodetector, to improve detection
Accuracy and sensitivity.And the light for carrying out initial calibration is arranged in electronic reading out device of the invention between light-emitting component
Detector realizes light modulation, calibration of the equipment before use, ensure that the accuracy of testing result.
Detailed description of the invention
Fig. 1 is the schematic perspective view of the electronic reading out device in the specific embodiment of the present invention.
Fig. 2 is the schematic diagram of the section structure of the electronic reading out device in the specific embodiment of the present invention.
Fig. 3 is the partial enlargement diagram of Fig. 2, wherein (A) is top view, (B) is front view.
Fig. 4 is the bottom schematic view of the electronic reading out device in the specific embodiment of the present invention.
Fig. 5 is the bottom schematic view of the electronic reading out device in another embodiment of the invention.
Fig. 6 is the schematical top view of the electronic reading out device of Fig. 5.
Fig. 7 is the exploded view of the electronic reading out device in the specific embodiment of the present invention.
Fig. 8 is the testing element schematic diagram in the specific embodiment of the present invention.
Appended drawing reference: 101 first light-emitting components, 102 second light-emitting components, 201 first photodetectors, the inspection of 202 second light
Survey device, 203 third photodetectors, 30 blocking elements, 301 first light-blocking members, 302 second light-blocking members, 303 third light-blocking parts
Part, 304 fourth gear light components, 305 fifth gear light components, 306 sixth gear light components, 307 the 7th light-blocking members, 308 the 8th gears
Light component, 309 the 9th light-blocking members, 310 the tenth light-blocking members, 40 testing elements, 401 sample absorbance areas, 402 reagent areas, 403
Test section, 404 reference regions, 405 control zones, 406 suction zones, the region near 407 and 408 test sections, 409 and 410 control zones
Neighbouring region, 50 notches, 501 first notches, 502 second notches, 60 substrates, 70 pedestals, 701 detection windows, 702 card slots,
703 grooves, 704 protrusions, 80 upper housings, 90 lower cases, 100 lids, 110 inhale lining bar, 120 front end conduction electrodes, 130 displays
Device, 140 power supply components, 150 buzzers.
It is described in detail
Structure of the present invention or technical term used in these are described further below.These explanations are only
Be only using example way be illustrated it is of the invention by the way of how to realize, any limit can not be constituted to the present invention
System.
Detection
Detection indicates chemical examination or tests a kind of substance or material to whether there is, for example, but it is not limited to this, chemical substance,
Organic compound, inorganic compound, metabolism product, drug or drug metabolite, organic organization or organic organization generation
Thank object, nucleic acid, protein or polymer.In addition, detection indicates the quantity of test substances or material.Furtherly, table is gone back in chemical examination
Show immune detection, chemical detection, enzyme detection etc..
Sample
It include biofluid (such as casing fluids or clinical sample with the sample that detection device of the invention can detecte
This).Liquid sample or fluid sample can from the sample of solid-state or semisolid, including excreta, biological tissue and
Food samples.The sample of solid-state or semisolid can be converted to liquid sample using any method appropriate, such as mix, smash
It is broken, macerate, be incubated for, dissolution or in a suitable solution (such as water, phosphate solution or other buffer solutions) using enzymatic hydrolysis make
With digestion of solid sample." biological sample " includes deriving from animal, plant and food samples, for example including from human or animal
Urine, saliva, blood and its ingredient, spinal fluid, vaginal fluid, sperm, excrement, sweat, secretion, tissue, organ, tumor, group
Knit the culture with organ, cell culture and medium.Preferred biological sample is urine.Food samples include the object of food processing
Matter, final products, meat, cheese, wine, milk and reference water.Plant sample includes being derived from any plant, plant tissue, and plant is thin
Born of the same parents' culture and medium." environmental samples " from environment (for example, from lake or the liquid sample of other water bodys, sewage
Sample, soil property sample, underground water, seawater and waste liquid sample).Environmental samples may also include sewage or other waste water.
Using the device of the invention and suitable testing element, any analyte can detecte.Preferably by the present invention
Device for early pregnancy detect.Preferred sample is urine specimen.
Analyte
It include but is not limited to creatinine, bilirubin, nitrite, egg with the analyte that the device of the invention detects
White (non-specificity), hormone (such as human chorionic promotes sex hormone, luteinizing hormone, follicular stimulating hormone etc.), blood, white blood cell,
Sugar, heavy metal or toxin, bacterial components (albumen or glucide as being directed to specific bacterial, such as colon bacillus 0157:
H7, staphylococcus, salmonella, fusobacterium, Campylobacter, L.monocytogenes, vibrio or cactus bacillus) and urine
Substance relevant to physiological characteristic in sample, such as pH and specific gravity.
In addition, can be used for detecting drug abuse, such as cocaine, amphetamine AMP, crystal methamphetamine MET, barbiturates
Salt BAR, sedative, lysergic acid diethylamide (LSD), inhibitor (downers, goofballs, barbs, blue devils,
Yellowjackets, methaqualone), the anti-antidepressant of tricyclic antidepressants (TCA), opiate, anxiolytic and hypnotic sedative agent etc..
It can be used for the detection that detection belongs to medical usage but is easy overdose using the device of the invention, such as the anti-suppression of tricyclic antidepressants
Strongly fragrant medicine (imipramine or the like) and Paracetamol etc..These drugs can resolve into different small molecule objects after being absorbed by the body
Matter, these small-molecule substances be present in the body fluid such as blood, urine, saliva, sweat or part body fluid there are above-mentioned small molecule objects
Matter.
Other any Clinical Urinary chemical analyses all cooperate apparatus of the present invention to be detected using lateral flow test format.
In one embodiment, analyte is any one detectable substance.Analyte in one embodiment
Matter includes a kind of labeled reagent, such as marks markd conjugate, and conjugate is illustrated to purpose analyte or purpose
The binding affinity of analyte analog.
In one embodiment, analyte includes a directly label, such as dyestuff or gold particle.In this way
The quantity that the accumulation of the substance of label can reflect detection zone or transmit light causes a kind of detectable influence.
In preferred mode, the analyte be HCG perhaps LH for detecting whether pregnancy or whether arranging
Ovum.
Testing element
A variety of testing elements can be with combined application into the present invention, and preferred test is first in certain embodiments of the present invention
Part is test-strips.Test-strips can there are many forms, for example, by using biological immune or test chemical form, for test sample
In analyte, such as drugs or indicate physical condition correlative metabolites.In some forms, test-strips are that have sample-adding
The water-absorbing material of area, reagent area and test section.Sample is added to sample application zone, flows into reagent area using capillarity.It is trying
Agent area, sample solubilising reagent simultaneously mixed can be used for detecting analyte (if there are analytes in sample).Band at this time
There is the sample of reagent to continue to flow to test section.Other reagents, such as molecule with analyte specific binding are fixed on
Test section.These reagents react with the analyte (if present) in sample and analyte are incorporated in the area, Huo Zheyu
Some reagent of reagent area combines.
In a specific embodiment, test-strips include for a kind of the specific with marker of analyte
Binding reagents, which is generally arranged at the reagent area of test-strips, and one kind can be with same analyte specific bond
Without the particular combination reagent of marker, which is fixed on the test in the downstream of the particular combination reagent with marker
Qu Zhong, when the liquid sample containing analyte is applied in test-strips, liquid sample flows on the test strip, the quilt
Substance is analyzed with the particular combination reagent with marker in conjunction with, one species complex of formation, wherein the marker is
Coloured.The complex moves further into test section, test section be fixed on test section without the specific of marker
Binding reagents are bonded another species complex, so that the analyte is detected in test section.Particularly, the inspection
Surveying includes accumulation of the marker in test section, and there are the accumulation that analyte often causes the marker in sample
Test-strips may include the transmitting that multiple material is used for liquid sample.One of material can be covered on another material
On, as filter paper is covered on nitrocellulose filter.One area of test-strips can select one or more materials, and another area selects
With other different one or more materials.Test-strips can be attached on certain support or hard surface and take for improving
Pinch the intensity of Test paper.
In the detection process, analyte is detected by signal generating system, is such as occurred using with analyte
One or more enzymes of specific reaction will be a kind of using such as aforementioned by the fixed method on the test strip of specific combinating substance
Or the composition of multi-signal generating system is fixed on the analyte test area of test-strips.The substance for generating signal can be loaded
On area, reagent area or test section, or entire test-strips, which can be full of on one or more materials of test-strips.Specifically
Ground, the detection is preferably including the accumulation of marker, usually accumulation of the marker in test section.The marker can be
The colored particles such as enzyme, radioactive isotope tracer, fluorescein, colloidal gold, colored latex.
Each area of test-strips can arrange in the following manner: sample application zone, reagent area, test section, control zone determine sample
Whether adulterated area, liquid sample uptake zone.Control zone is located at after test section.All areas can be arranged at only with a kind of material
On one test paper of material.The direction that each area can directly and liquid sample contacts or different areas is flowed according to liquid sample
Arrangement, the end in each area is connected and is overlapped with the front end in another area.Material used can be the preferable material of water imbibition such as
Filter paper, glass or nitrocellulose filter etc. can also use other forms.
It is applied to lateral effluent reagent strip (the Lateral flowtest that testing element of the invention can be known as
Strip), the specific structure of these detection reagent items and testing principle are known in persons skilled in the art in the prior art
Technology, the form as disclosed in US6156271, US5504013, EP728309 etc..Testing element may include multiple areas, such as
Sample collection area, mark zone, test section and suction zones, sample collection area include sample receiving pad, and mark zone includes label pad, are inhaled
Pool may include water absorption pad, wherein include that can detect whether the necessary chemical substance containing analyte, example on detection zone
Such as immunoreagent or enzymology reagent.It certainly, can also include control zone in the downstream of test section, in general, control zone and survey
Examination area occurs in the form of horizontal line, is detection line or control line.Dry chemistry reagent ingredient, example are had on general detection reagent item
Such as fixed antibody or other reagents, after encountering liquid sample, liquid is flowed with capillarity along test-strips, with
Flowing, allows dry agent formulations to be dissolved in liquid, thus react to next region and the dry reagent in the area, thus into
The necessary detection of row.Liquid flowing mainly carries out through capillary action.
In the specific embodiment of the present invention, see in Fig. 7, testing element 40 has sample absorbance area 401, reagent
Area 402, test section 403, reference region 404, control zone 405 and suction zones 406.Test section 403 is that light letter is formed in testing element
Number region, be the accumulation area or storage area of the marker of the coloured binding reagents of such as graininess, indicate whether that there are to be analyzed
Substance, certainly, when not having test analyte, some analyses are as replaced analysis that may will form signal.Control zone 405 is test
Whether the region that another is capable of forming optical signal on element detects whether correctly to carry out and/or have in conjunction with reality for showing
Effect, it is unrelated with the presence or absence of substance to be analyzed.Reference region 404 is the region between test section and control zone, is a shape
At the region of " background " signal, such as the signal can be used for calibrating assay readings device and/or provide and can refer to for test signal
Background signal.Reference region can also be not provided between test section and control zone.
In the specific embodiment of the present invention, the test section 403 and/or control zone 405 of testing element and this hair
The light-emitting component of bright electronic reading out device is corresponding, and the light that the light-emitting component issues is incident on the test section of testing element
403 or control zone 405 on, and be incident on corresponding photodetector from the light that the area reflects, so that generating one can
Detected electric signal indicates the amount of analyte in the area.
In other modes, which includes blocking element 30 for example shown in Fig. 3, and blocking element 30 is by photodetector
It separates with light-emitting component, so that the light for avoiding light-emitting component from issuing is directly entered photodetector, and guides from testing element
Light enters photodetector, or is substantially received by photodetector.Further, blocking element 30 is to corresponding from testing element 40
The light in one or more regions stopped, guide the illumination of light-emitting component to be mapped to testing element in addition corresponding one or more
On a region, so that guidance is from testing element, in addition the light in one or more regions enters photodetector accordingly, preferably keeps off
Light of the optical element guidance from testing element test section and control zone enters photodetector, or is substantially received by photodetector,
It will be made below specifically illustrating.
Light-emitting component and photodetector
Light-emitting component and photodetector constitute Systems for optical inspection, detect the product of the analyte on testing element
It is tired.Wherein, light-emitting component is a variety of to shine for emitting beam and being irradiated to testing element one or more areas accordingly
Light source be adapted to as light-emitting component.In a specific embodiment, light-emitting component is light emitting diode, such as LED light.
Photodetector is converted into the electric signal that can be detected for detecting the reflected light being irradiated to thereon, the electric signal and test member
The amount of the marker accumulated on part is directly proportional, wherein and reflected light is that the light that light-emitting component issues is formed after element reflects after tested,
Also it is considered the light from testing element, although the light is substantially to carry out self-emission device.It is embodied at one
In mode, photodetector is photodiode (PD detector).The suitably skill of light-emitting component and photodetector for this field
Art personnel are well known.
In a specific embodiment, electronic reading out device of the invention includes at least two photodetectors, including
First photodetector 201 and the second photodetector 202, first photodetector 201 and the second photodetector 202 connect respectively
Receive the reflection light from testing element corresponding region.In a preferred mode, first photodetector 201 and
Two photodetectors 202 are set to the position where corresponding testing element test section and control zone, receive come from testing element respectively
The reflection light of test section and control zone.In a preferred mode, first photodetector 201 and the second light detection
202 linear array of device.
In a specific embodiment, electronic reading out device of the invention includes at least one light-emitting component and at least
Two photodetectors.Wherein, at least one described light-emitting component includes the first light-emitting component 101, first light-emitting component
101 illumination issued are mapped in the corresponding one or more areas of testing element 40, and the corresponding region of light element 40 after tested is anti-
It is received after penetrating by the first photodetector 201 and the second photodetector 202.In a preferred mode, the first light inspection
It surveys device 201 and the second photodetector 202 linearly arranges, first light-emitting component 101 is located at 201 He of the first photodetector
The opposite of second photodetector 202 is arranged in parallel, i.e. the first light detection with the first photodetector 201 and the second photodetector 202
Device 201 and the second photodetector 202 share a light-emitting component.In one preferred embodiment, it described first shines
Element 101, the first photodetector 201 and the second photodetector 202 are arranged in " product " font.
In another particular embodiment of the invention, electronic reading out device of the invention includes at least two light-emitting components and extremely
Few two photodetectors, wherein at least two light-emitting components include the first light-emitting component 101 and the second light-emitting component
102, the light that first light-emitting component 101 and the second light-emitting component 102 issue irradiates testing element 40 corresponding one respectively
Or in multiple areas, light receives (Fig. 4) by photodetector 201 and photodetector 202 respectively after reflection.A preferred side
In formula, the photodetector 201 is correspondingly arranged with the first light-emitting component 101, photodetector 202 and the second light-emitting component 102
It is correspondingly arranged, photodetector 201 and 202 can be received from testing element at least two respectively spatially by isolated region institute
The light of sending.In a preferred mode, first light-emitting component 101 is located at the opposite of the first photodetector 201, with
Linearly arrangement, second light-emitting component 102 are located at the opposite of the second photodetector 202 to first photodetector 201, with the
The two linearly arrangements of photodetector 202.In a preferred mode, the illumination that the first light-emitting component 101 issues is mapped to test
The test section of element 40 and the region 407 and 408 (Fig. 8) near test section, such as it is irradiated to test section 403 and/or part
Reference region 404 and/or portion of reagent area 402, the illumination that the second light-emitting component 102 issues are mapped to the control zone 405 of testing element
And the region 409 and 410 (Fig. 8) near control zone, such as it is irradiated to control zone 405 and/or the part reference of testing element
Area 404 and/or part suction zones 406, photodetector 201 receive near test section 403 and test section from testing element
Region light, photodetector 202 receives the light in the region near the control zone 405 from testing element and control zone.?
In one preferred embodiment, the illumination that the first light-emitting component 101 issues is mapped to the test section 403 of testing element 40, and second
The illumination that light-emitting component 102 issues is mapped to the control zone 405 of testing element, and photodetector 201 and photodetector 202 receive respectively
The light of test section 403 and control zone 405 from testing element.Light-emitting component and photodetector correspond, can be more acurrate
The optical information of ground reaction test element each region guarantees the accuracy and sensitivity of detection.In a preferred embodiment party
In formula, first light-emitting component 101 and the second linearly arrangement of light-emitting component 102,201 He of the first photodetector
The second linearly arrangement of photodetector 202.It is preferred that two light-emitting components successively shine, i.e. transmitting light has surrounding time difference,
Form the time difference that shines.It is preferred that the energy coincidence of the light of two light-emitting components transmitting.
In another particular embodiment of the invention, electronic reading out device of the invention includes at least two light-emitting components and extremely
Few three photodetectors, wherein at least two light-emitting components include the first light-emitting component 101 and the second light-emitting component
102, the light that first light-emitting component 101 and the second light-emitting component 102 issue irradiates testing element 40 corresponding one respectively
Or multiple areas, light is received by photodetector 201 and photodetector 202 respectively after reflection, and third photodetector 203 is used for
Electronic reading out device of the invention is carried out using preceding initial calibration or light modulation (Fig. 5 and Fig. 6).
In a preferred mode, the photodetector 201 is correspondingly arranged with the first light-emitting component 101, light detection
Device 202 is correspondingly arranged with the second light-emitting component 102, and first light-emitting component 101 and the second light-emitting component 102 are linearly arranged
Column, first photodetector 201 and the second photodetector 202 linearly arrangement, in first light-emitting component 101 and the
Third photodetector 203 is equipped between two light emitting 102.In one preferred embodiment, the third light detection
Device 203 is between the first light-emitting component 101 and the second light-emitting component 102.In one preferred embodiment, described
Three photodetectors 203 between the first light-emitting component 101 and the second light-emitting component 102, and with the first light-emitting component 101 and
Two light emitting 102 linearly arranges.
Here in linear array, preferably the first light-emitting component 101 and the second light-emitting component 102 are located at same
Straight line, the first photodetector 201 and the second photodetector 202 are located at same straight line, or, the first light-emitting component 101 and the first light
Detector 201 is located at same straight line or the second light-emitting component 102 and the second photodetector 202 is located at same straight line, or, first
Light-emitting component 101, the second light-emitting component 102 and third photodetector 203 are located at same straight line, it is not intended that can only
Be located along the same line, between two light-emitting components and/or between two photodetectors and/or the first light-emitting component 101 with
Between first photodetector 201 and/or between the second light-emitting component 201 and the second photodetector 202 and/or first shines member
It can be mutually staggered between part 101, the second light-emitting component 102 and third photodetector 203, such as the first light-emitting component 101,
It can be arranged in " product " font between two light emitting 102 and third photodetector 203, because testing element generally has centainly
Width, the light for receiving light-emitting component be there is certain area, and from testing element reflect or issue light also have
Certain area is of virtually the light beam of certain 3D shape or the region of light, as long as photodetector is in these three-dimensional shapeds
Within the light beam of shape or the region of light, all it is possible.So slightly position between light-emitting component and/or between photodetector
The offset set also belongs to a scheme of the invention.
Blocking element
In some preferred modes, on the specific region that the light issued from light-emitting component is incident on testing element, through surveying
Enter photodetector after trying element reflection, in this case, light-emitting component and photodetector are typically provided at testing element
It is ipsilateral, therefore, in some modes, it is desirable to provide a blocking element 30, the element allow the light on testing element by light
Detector receives.30 one side of blocking element is for avoiding the light for carrying out self-emission device from being directly entered photodetector, on the other hand
For allowing the illumination from a certain specific region of testing element to be received by photodetector, and stop the light substantially quilt in other regions
Photodetector receives.Therefore, change light-emitting component sending and/or from testing element light by setting blocking element
Path allows the light for carrying out self-emission device to be incident on testing element accordingly in one or more areas, and allows from testing element phase
The light in one or more areas answered is received by photodetector reception or essence by photodetector.Light path and light-emitting component and survey
The height or width for trying the distance between the distance between element, blocking element and light-emitting component and blocking element are related.One
As, light-emitting component issues light, it is desirable to is irradiated in the corresponding region on testing element as far as possible, and light-emitting component is not intended to send out
Illumination is mapped to other regions unrelated with testing result out, or the light of light-emitting component is not intended to directly to be received by photodetector, this
Blocking element generally can be all set when a to prevent light-emitting component from issuing the direct of light and be received by photodetector.Although subtracting in this way
Light interference, still, if allowing the light from testing element, especially whether the light of target area is not received by photodetector,
Thus further reduce interference of the invalid light to photodetector, so that testing result is sensitiveer reliable.
When the illumination that light-emitting component issues is mapped in test-strips 40, generally, of course, it is desirable to the survey being irradiated in test-strips
Treated substance, such as antibody in area, such as previous test zone is tried, which has the accumulation of colored particle substance, from
And cause the variation of region sending light, it is desirable to which these variations are received by photodetector as far as possible, so as to more sensitive
These optical changes are reacted, so that test result is more accurate.But during this time, the light that light-emitting component issues not only may be used
To be irradiated to specific region, such as test section 403, other regions except test section, such as test section can also be irradiated to
Reference region 404 between 403 and control zone 405 and the region near test section 407 and 408, other areas except test section
The light in domain can also be irradiated on photodetector, and these light can not reflect the variation of test section light, but belong to interference light
Type, if interference light is received by photodetector, it will cause the interference to normal light, thus identification test that cannot be sensitive
The variation in area causes the inaccuracy of test result.And the interference light from test section is stopped to be examined by light using blocking element
It surveys device to receive, so that the light from specific region be allowed to be received by photodetector as far as possible, improves the susceptibility of detection in this way.
In some modes, blocking element 30 can be used to the light and/or carry out self-test that guidance light-emitting component issues
The path of the light of element so that light-emitting component be allowed to irradiate the specific specific region of testing element, or allows from testing element
Light (such as a certain specific region) is received by photodetector as far as possible.
The material of blocking element 30 needs to meet light-blocking function, and preferably blocking element 30 is that optical baffle is (such as opaque
And the visible light part of pop cannot be transmitted), suitable material includes the synthetic plastic resin of dense black or furvous or black
Deng, such as PPO (polyphenylene oxide).
In a preferred embodiment, the device includes at least two photodetectors, including the first light
Detector 201 and the second photodetector 202, wherein one at least two photodetectors is isolated in independent space.
Referring to Fig.1-3, at least one of two photodetectors are separated only by the way that blocking element 30 is arranged around photodetector
In vertical space.Independent space refers to the photodetector separated relative to light-emitting component, testing element and other light
It is enclosed in for detector in the space of a relative closure, so that certain light outside this space cannot be introduced into the sky
In, specifically, the photodetector is not contacted with light-emitting component, so that the light that light-emitting component issues can not be directly entered light inspection
Device is surveyed, which does not contact with the partial region of testing element or testing element, so that from testing element or test member
The light of part partial region cannot be introduced into the photodetector, and the photodetector is not contacted with other photodetector, so that into
Entering the light in the space of the opposing seal can not be received by other photodetector.In a preferred mode, in the gear
There is the notch 50 for allowing the light from testing element to penetrate, the setting of the notch is so that corresponding from testing element on optical element 30
The light in region can enter photodetector by the notch, and the light from the other region of testing element cannot be introduced into light detection
Device.50 one side of notch is for guiding the light of testing element corresponding region to enter photodetector, on the other hand for guiding hair
The path for the light that optical element issues, enables the light of the light-emitting component testing element as much as possible that is irradiated to wish to be irradiated to
Region.In a preferred mode, the notch 50 is set to where the test section or control zone of corresponding testing element
Position, for guiding the light of test section or control zone from testing element to be received by photodetector.In a preferred mode
In, the notch 50 includes the first notch 501 and/or the second notch 502.
In a preferred mode, the blocking element 30 includes for separating photodetector and light-emitting component
One light-blocking member 301, the first light-blocking member 301 is between light-emitting component and photodetector, for guiding light-emitting component to issue
Light path, allow it to be irradiated to some or multiple regions of testing element, without shining directly on photodetector.?
In one preferred mode, there is the first notch 501 on first light-blocking member, specifically, in the first light-blocking member 301
There is a recess, when testing element 40 is fixed on electronic reading out device, described first close to the position of testing element 40
Light-blocking member 301 forms the first notch 501 between recess and testing element 40, and the presence of first notch 501 is reduced
On the one hand the blocking of first light of the light-blocking member 301 to light-emitting component and the reflected light from testing element makes from surveying
The light for trying element corresponding region can enter photodetector by the first notch 501, on the other hand allow the light of light-emitting component bigger
Range is irradiated on the corresponding region of testing element.In a preferred mode, which opens to be inclined
Mouthful, specifically, the recess being located on the first light-blocking member 301 is slope surface in the side of neighbouring photodetector and/or light-emitting component,
To form inclined first notch 501, the setting of the slope surface can be further reduced the first light-blocking member 301 to testing element
Reflection light and/or light-emitting component issue light blocking, be on the one hand conducive to the light from 40 corresponding region of testing element
Line enters photodetector, to ensure that photodetector receives the reflected light from testing element corresponding region maximum area, another party
The light corresponding region as much as possible for being irradiated to testing element that face issues light-emitting component, so that detection effect is more preferable.One
In a preferred mode, the test section 403 or control zone 405 of the corresponding testing element of first notch 501 are arranged.At one
In preferred mode, the p-wire of the corresponding testing element of first notch 501 or the position setting where control line.One
In a preferred mode, the width of the first notch 501, that is, the length of the groove on the first light-blocking member 301 are equal to
Either less than the width of the test section of testing element 403 or control zone 405.
In a preferred mode, the blocking element 30 further comprises for separating photodetector and testing element
The second light-blocking member 302, second light-blocking member 302 is set between photodetector and testing element, covering or portion
Divide coverage test element and/or photodetector.When testing element is fixed on reading plotter, the second light-blocking member 302 with
Testing element 40 contacts, the partial region of coverage test element 40.In a preferred mode, in the second light-blocking member 302
It is upper that there is the second notch 502, when testing element 40 is fixed on reading plotter, on testing element with second notch 502
The region being in contact is not covered with.The presence of second notch 502 reduces the second light-blocking member 302 to the light of light-emitting component
With the blocking of the reflected light from testing element, on the one hand to be in contact from testing element with second notch not by
The light in the region that the second blocking element is covered can enter photodetector by second notch 502, on the other hand allow luminous
The light of element is larger range of to be irradiated on the corresponding region of testing element, that is, allows the light of light-emitting component that can be irradiated to survey
On the region not covered by the second blocking element 302 being in contact on examination element with second notch.Mode in, it is described
The corresponding testing element of the second notch 502 test section 403 or control zone 405 be arranged, i.e., when testing element is fixed on reading
When on device, the partial test area of testing element or control zone are not covered by the second light-blocking member 302.It is preferred at one
In mode, the p-wire of the corresponding testing element of second notch 502 or the position setting where control line.Preferably at one
Mode in, the width of the second notch 502 is equal to or less than the test section 403 of testing element or the width of control zone 405.
Second light-blocking member 302 is considered a laminated structure being arranged between testing element and photodetector, the sheet
The region that structure is hollowed out in the test section of corresponding testing element or the position of control zone there are one, to form the second notch
502.Second light-blocking member 302 also may be considered that the fourth gear light component for being divided into and being separated from each other at the second notch 502
304 and fifth gear light component 305, it is also assumed that the second light-blocking member 302 is 304 He of fourth gear light component by being separated from each other
Fifth gear light component 305 forms, and the distance between fourth gear light component 304 and fifth gear light component 305 are equal to the second notch 502
Width.
In a preferred mode, first notch 501 is connected with the second notch 502.Specifically, first
Notch 501 and the second notch 502 are set to the same position for test section 403 or control zone 405, and in the first notch
501 and second do not have connector between notch 502, that is to say, that the first notch 501 and the second notch 502 combine so that
Blocking element 30 has the notch 50 of a L-type.In a preferred mode, the width of first notch 501 is equal to the
The width of two notches 502.In a preferred mode, the width of the width of first notch 501 and the second notch 502 is not
It is equal.In a preferred mode, there is a connector in the junction of the first notch 501 and the second notch 502, so that
First notch 501 is not connected to the second notch 502, and the shapes and sizes of connector are unrestricted, can be strip structure, can also
Laminated structure is thought, as long as the first notch 501 and the second notch 502 can be made not exclusively capped.A preferred side
In formula, the position where the first notch 501 and the second notch 502 can have certain offset, because of test section 403 or control zone
405 width has certain range, has certain deviation between the first notch 501 and the second notch 502 it is also ensured that lacking
Mouth 50 is in the position where test section 403 or control zone 405.In a preferred mode, when on the second light-blocking member 302
When with the second notch 502, can not have the first notch 501 on the first light-blocking member 301.
In a preferred mode, the blocking element 30 further comprises for separating at least two photodetectors
Third light-blocking member 303.The third light-blocking member 303 is located between two photodetectors, and two photodetectors are separated.
In a preferred mode, do not have notch on the third light-blocking member 303, so that by the compartment
Light not can enter in other photodetector.In a preferred mode, two photodetectors share one the
Three light-blocking members 303, i.e., two adjacent photodetectors by a third light-blocking member 303 being set between them by every
It opens.In a preferred mode, two photodetectors by mutually independent two third light-blocking members 303 by every
It opens.In a preferred mode, mutually independent two third gear for being used to separate two adjacent photodetectors
Light component 303 is at a distance.In a preferred mode, the phase for being used to separate two adjacent photodetectors
Mutual independent two third light-blocking members 303 are in longitudinal parallel.In a preferred mode, described is adjacent for separating
Region between mutually independent two third light-blocking members 303 of two photodetectors corresponds to the reference region 404 of testing element.
In some preferred modes, testing element 40 can be to carry out analyte quality detection and be introduced into electronics
The individual equipment of reading plotter, such as cross-flow type test-strips, testing element 40 and the electronic reading out device are with dismountable side
Formula is combined, when testing element 40 and electronic reading out device are fixed together, the light-emitting component, photodetector with
And testing element 40 forms the detection space for detecting analyte.In some embodiments, testing element 40 is laterally
The test strip of flowing has sample absorbance area 401, reagent area 402, test section 403, reference region 404,405 and of control zone
Suction zones 406, when testing element 40 is fixed on reading plotter, the photodetector corresponds to test section or control zone setting,
The illumination that first light-blocking member 301 guidance light-emitting component issues is mapped to testing element accordingly on one or more regions, light
Enter photodetector after the corresponding region reflection of element after tested, range of exposures of the light-emitting component on testing element and from survey
The range of the light of photodetector is reflected on examination element at a distance from light-emitting component and testing element 40, the first light-blocking member
301 height is related to the coverage area of the second light-blocking member 302.
In a preferred mode, the first light-blocking member 301 is connected with third light-blocking member 303.Preferably at one
Mode in, the first light-blocking member 301 and angle of the third light-blocking member 303 in junction are 90 °, i.e. the first light-blocking member
303 with the perpendicular structure of third light-blocking member 303.In a preferred mode, it is light-blocking that the second light-blocking member 302 is located at first
On component 301 and third light-blocking member 303, i.e., the second light-blocking member 302 is covered on the first light-blocking member 301 and third is light-blocking
On component 303.In a preferred mode, the second light-blocking member 302 and the first light-blocking member 301 and third light-blocking member
303 perpendicular structures.In a preferred mode, the first light-blocking member 301 it is longitudinal extend respectively with 40 phase of testing element
It hands over, and vertical with the short axle of testing element 40, the second light-blocking member 302 is in contact with testing element 40 and in longitudinal parallel junction
Longitudinal extend of structure, third light-blocking member 303 is intersected with testing element 40, and vertical with the long axis of testing element 40.At one
In preferred mode, the blocking element that is made of the first light-blocking member 301, the second light-blocking member 302 and third light-blocking member 303
At least one photodetector is separated in independent space, or also can be regarded as by the first light-blocking member 301, third gear
The blocking element that light component 303, fourth gear light component 304 and fifth gear light component 305 form divides at least one photodetector
It is interposed between in independent space.
In a preferred embodiment, the device further comprises light-emitting component, the luminous member
The test section 403 or the position where control zone 405 that part is set to corresponding testing element.In one preferred embodiment,
The light-emitting component at least two is respectively arranged at the opposite of the first photodetector 201 and the second photodetector 202, hair
There is blocking element 30 between optical element and photodetector.In a preferred mode, between two light-emitting components
Without blocking element 30.In a preferred mode, there is third photodetector 203 between two light-emitting components, uses
In to equipment progress initial calibration or light modulation.
Electronic reading out device
Electronic reading out device refers to the device of the test result on read test element, and the present invention mentions electronical reading dress
It can not include testing element 40 when setting, also may include testing element 40.As described above, testing element 40 can be
The individual equipment of electronic reading out device is introduced into order to carry out analyte quality detection or testing element 40 is that electronics is read
Counting apparatus inalienable part.If testing element 40 is the indivisible component part of the electronic reading out device, the electronics
Reading plotter may include the testing element 40 for being able to carry out microfluid detection or lateral chromatography detection.The electronic reading out device
It may include the space for accommodating testing element 40, but be not necessarily required to containing testing element 40, testing element 40 can
To be combined when subsequent any suitable with electronic reading out device.When the electronic reading out device includes testing element 40
When, the electronic reading out device be considered for detect in sample whether the detection device containing analyte,
Electronic reading out device i.e. of the invention is substantially a kind of for detecting the detection device of analyte in sample, utilizes this hair
Bright device and suitable testing element, can detecte any analyte.It is examined preferably by the device of the invention for early pregnancy
It surveys.
In a specific embodiment, electronic reading out device of the invention includes the first light-emitting component 101 and second
Light-emitting component 102 issues light and is irradiated in the corresponding one or more areas of testing element 40;First photodetector 201 and
Two photodetectors 202 receive the reflection light in the corresponding one or more areas of the testing element 40;Blocking element,
The path of light for guiding light-emitting component to issue and/or the light from testing element, by the first photodetector 201 and second
Photodetector 202 separates in independent space.In a preferred mode, the first light-emitting component 101 and the first light detection
Device 201 is set to the position where corresponding testing element test section 403, and the second light-emitting component 102 and the second photodetector 202 are set
It is placed in the position where corresponding testing element control zone 405.Wherein, including the first light-blocking member 301, the second light-blocking member 302
First photodetector 201 is separated in independent space with the blocking element of third light-blocking member 303, including sixth gear light portion
The blocking element of part 306, the 7th light-blocking member 307 and the 8th light-blocking member 308 separates the second photodetector 202 independent
In space.In a preferred mode, separating has notch 50, the notch on the blocking element of the first photodetector 201
50 correspond to the test section 403 of testing element, which includes 501 He of the first notch on the first light-blocking member 301
The second notch 502 on the second light-blocking member 302, the first notch 501 are connected with the second notch 502.Second light-blocking part
Part 302 is divided into the fourth gear light component 304 and fifth gear light component 305 being separated from each other at the second notch 502, thus
It can be regarded as including the first light-blocking member 301, third light-blocking member 303, fourth gear light component 304 and fifth gear light component
First photodetector 201 is enclosed in independent space by 305 blocking element 30.In a preferred mode, separate the
There is notch 50, the notch 50 corresponds to the control zone 405 of testing element, should on the blocking element 30 of two photodetectors 202
Notch 50 includes the first notch 501 on sixth gear light component 306 and the second notch on the 7th light-blocking member 307
502, the first notch 501 is connected with the second notch 502.7th light-blocking member 307 is divided into mutually at the second notch 502
Thus the 9th light-blocking member 309 and the tenth light-blocking member 310 of separation also can be regarded as including sixth gear light component 306, the
The blocking element 30 of eight light-blocking members 308, the 9th light-blocking member 309 and the tenth light-blocking member 310 encloses the second photodetector 202
It closes in independent space (Fig. 3).
In a specific mode, as shown in figure 3, the light that the first light-emitting component 101 issues can be irradiated to test member
Region 407 and 408 near the test section 403 of part and test section, due to fourth gear light component 304 and fifth gear light component
305 presence, so that the reflected light in the region after region and test section before test section is by fourth gear light component 304
Stop with fifth gear light component 305 without can enter the first photodetector 201;Due in fourth gear light component 304 and fifth gear
There is the second notch 502, which is set to the position where corresponding testing element test section 403 between light component 305
It sets, the presence of second notch 502 covers the test section 403 on the first photodetector 201 by blocking element, from
And the light that light-emitting component is issued more is irradiated to the test section 403 of testing element, but also coming from testing element
The light of test section 403 can be received by the first photodetector 201.In a specific mode, the second light-emitting component 102 is issued
Light can be irradiated to the region 409 and 410 near the control zone 405 and control zone of testing element, due to the 9th light-blocking part
The presence of part 309 and the tenth light-blocking member 310, so that the reflection in the region after region and control zone before control zone
Light is stopped by the 9th light-blocking member 309 and the tenth light-blocking member 310 without can enter the second photodetector 202;Due to the 9th
There is the second notch 502, which is set to corresponding test member between light-blocking member 309 and the tenth light-blocking member 310
Position where part control zone 405, the presence of second notch 502 do not have the control zone 405 on the second photodetector 202
Have and is covered by blocking element, so that the light that light-emitting component issues can more be irradiated to the control zone 405 of testing element,
But also the light from testing element control zone 405 can be received by the second photodetector 202.
In the present invention, the composition blocking element 30 each light-blocking member mutual cooperation further limit light path and
Photoirradiated surface product, specifically, the illumination that the first light-emitting component 101 issues is mapped to the test section 403 of testing element 40, and then comes from
The light of testing element test section 403 is received by notch 50 by photodetector 201, the light irradiation that the second light-emitting component 102 issues
Pass through notch 50 by photodetector 202 to the control zone of testing element 40 405, and then from the light of testing element control zone 405
It receives, is optimized by above-mentioned light path so that photodetector only receives test section 403 from testing element and control zone 405
Light, so that the effective light for being able to reflect testing result from testing element is received by photodetector and avoids other invalid light
Into photodetector, detection sensitivity and accuracy are improved comprehensively.Also, the setting of notch is so that first shines on blocking element
The light test section 403 as much as possible for being respectively radiated to testing element and control that element 101 and the second light-emitting component 102 issue
Area 405, and then received after tested element reflection by the first photodetector 201 and the second photodetector 202, not only reduce gear
Blocking of the optical element to light-emitting component, also defines the path of the light from testing element target area.
In a specific embodiment, reading plotter of the invention further comprises substrate 60 and pedestal 70, wherein
Light-emitting component and photodetector are located on substrate 60, and the substrate 60 is pcb board;There is a detection window on the pedestal 70
701, the blocking element is located in the detection window 701 of pedestal 70.When substrate 60 and pedestal 70 are combined, testing element
40 when being fixed on pedestal 70, and detection window 701 is by one of light-emitting component, photodetector 201 and testing element 40 or more
A area is enclosed in a closed space.
In a specific embodiment, reading plotter of the invention further comprises a shell, is read for supporting
The component of counting apparatus, and/or the influence of external environment is protected them from, the shell is by upper housing 80, lower case 90 and lid
Body 100 forms.
In one preferred embodiment, which includes a processor, for receiving electric signal and carrying out
Analysis and result judgement.Processor, which controls two light-emitting components and successively shines, irradiates detection zone 403 and the control of testing element 40
Area 405, photodetector successively receive the reflection light from test section 403 and control zone 405 and are converted into electric signal, processor
The electric signal for receiving photodetector carries out reading and analysis processing.
In one preferred embodiment, which further includes a display 130 and power supply component 140.Place
Reason device shows processing result on the display 130, to facilitate observation testing result.Power supply component 140 is used for entire photoelectricity
Detection system power supply, can use such as button cell power supply component.
In one preferred embodiment, which further includes a buzzer 150, for prompting detection procedure
Or testing result.
It is to be appreciated that " the first light-blocking member, the second light-blocking member ..., first shine term in the present invention
Element, the second light-emitting component, the first photodetector, the second photodetector, the first notch, second notch etc. " is just for the sake of just
The title used by the structure for illustrating electronic reading out device of the invention can not constitute any limitation to the present invention.
Dismountable combination
Dismountable combination refers to that the connection relationship between two components is in several different states or position is closed
System, such as when being the component in two physical significances, can be at the beginning it is separated, at suitable first
It connects or combines, at suitable second, two components can be allowed to separate, this is separately physical significance
On space separate without contact.Alternatively, two components are combined at the beginning, when in a suitable case, Ke Yirang
The space that two components are formed in physical significance separates.Again alternatively, two objects be at the beginning it is separated, combined when needs
Certain function is completed together, is then separated again, or later in order to which certain purpose is combined again.In short, the two group
Separating between being combined or both is readily to carry out, it is this combine or be separately can repeat it is more
Secondary circulation, it is of course also possible to be disposably to combine and separate.Furthermore it is possible to removably combined between two components,
Three or three be can be with dismountable combination two-by-two between upper-part.
It should be noted that it can be directly in another yuan when an element referred to as " is fixed on " another element
On part or there may also be elements placed in the middle.When an element is considered as " connection " another element, it be can be directly
It is connected to another element or may be simultaneously present centering elements.Term "and/or" used in the present invention include one or
Any and all combinations of multiple relevant listed items.
With reference to Fig. 1 and Fig. 7, in some preferred embodiments, blocking element is located at the detection window of pedestal 70
In 701, light-emitting component and photodetector are set on substrate 60, and substrate 60 and pedestal 70 are removably connected, combine or tied
It closes.In one preferred embodiment, testing element 40 is the specific installation for introducing reading plotter, testing element 40 and reading
Device is removably connected, combines or is combined, and pedestal 70 is equipped with the card slot 702 for accommodating testing element 40, and testing element 40 exists
It is combined when appropriate with pedestal.When substrate 60 and pedestal 70 are combined, and testing element 40 is fixed on pedestal 70, inspection
It surveys window 701 and one or more areas of light-emitting component, photodetector and testing element 40 is enclosed in a closed space
It is interior and carry out the reading or detection.
Detection method
The present invention provides a kind of method of the test result of read test element, provides foregoing electronical reading dress
It sets, which includes: at least two photodetectors, including the first photodetector 201 and the second photodetector 202, for receiving
Reflection light from testing element corresponding region, which is characterized in that one at least two photodetectors is divided
It is interposed between in independent space.
Method of the invention is by allowing light-emitting component to shine, after light is radiated at the corresponding region of testing element, through reflecting
It is received afterwards by photodetector, forms the electric signal that can be detected then to carry out the judgement of test result.This electric signal be by
Caused by the accumulation of marker, meanwhile, the amount of analyte in sample is also depended on, to detect analyte in sample
The amount of matter.
In a preferred mode, by the blocking element 30 that is enclosed in around photodetector by least one light detection
Device separates in independent space, and the light from testing element specific region is allowed to be able to enter photodetector.
In a preferred mode, there is the notch for allowing the light from testing element to penetrate on the blocking element 30
50, allow the light from testing element specific region to enter photodetector by the notch 50.
In a preferred mode, the notch is set to 405 institute of test section 403 or control zone of corresponding testing element
Position, allow the light from testing element test section 403 or control zone 405 by the notch 50 enter photodetector.
In a preferred mode, the notch includes the first notch 501 and/or the second notch 502.
In a preferred mode, the blocking element 30 includes first for separating photodetector and light-emitting component
Light-blocking member 301, the first frequency modulated light component 301 allows the illumination for carrying out self-emission device to be mapped on testing element, without directly shining
It is mapped on photodetector, there is the first notch 501 on first light-blocking member 301.
In a preferred mode, first notch 501 is inclined notch.
In a preferred mode, the blocking element 30 further comprises for separating photodetector and testing element
40 the second light-blocking member 302, second light-blocking member 302 allow the illumination for carrying out self-emission device to be mapped to the corresponding of testing element
Region without being irradiated to other regions, or allows the light from testing element specific region to enter photodetector, the second gear
There is the second notch 502 on light component 302.
In a preferred mode, second notch 502 is connected with the first notch 501.
In a preferred mode, the blocking element 30 further comprises for separating at least two light detection
The third light-blocking member 303 of device does not have notch on the third light-blocking member 303.
In a preferred mode, described device further includes light-emitting component, and the light-emitting component is set to corresponding survey
The test section 403 or the position where control zone 405 for trying element, allow the illumination of light-emitting component to be mapped to the test section of testing element
403 or control zone 405.
In a preferred mode, the light-emitting component at least two, including the first light-emitting component 101 and second
Light-emitting component 102 does not have blocking element 30 between at least two light-emitting components.
It further include third photodetector 203 between at least two light-emitting components in a preferred mode.
In a preferred mode, at least two light-emitting components and/or third photodetector 203 are linearly arranged
Column.
In a preferred mode, the first light-emitting component 101 and the second light-emitting component 102 is allowed successively to shine, light shines
It penetrates on the test section of testing element 403 and control zone 405, light enters the first photodetector 201 and the second light after reflection
Detector 202 is formed for determining testing result electric signal, for determining test result.
Using electronic reading out device read test element of the invention test result or carry out analyte quality detection when
The step of are as follows: (1) process control the first light-emitting component 101 and the second light-emitting component 102 shine, and third photodetector 203 is to setting
It is standby to carry out initial calibration or light modulation;(2) liquid sample is applied on testing element 40, liquid 40 flowing on testing element,
Marker is accumulated in the test section of testing element 403;(3) process control the first light-emitting component 101 and the second light-emitting component 102 according to
It is secondary to shine, wherein on the test section 403 that the illumination from the first light-emitting component 101 is mapped to testing element, to pass through notch after reflection
50 are received by the first photodetector 201;On the control zone 405 that illumination from the second light-emitting component 102 is mapped to testing element, instead
It is received by notch 50 by the second photodetector 201 after penetrating;(4) first photodetectors 201 and the formation of the second light detection 202 can quilts
The electric signal of detection carries out the judgement and analysis of test result.
Specific embodiment
Below in conjunction with attached drawing, the technical scheme in the embodiment of the invention is clearly and completely described, described
Embodiment is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiment of the present invention, this field is general
Logical technical staff every other technical solution obtained without making creative work, belongs to guarantor of the present invention
The range of shield.
It is to be appreciated that term " on ", " before ", " later ", " except " etc. instructions orientation or positional relationship
To be based on the orientation or positional relationship shown in the drawings, it is only for convenient for the description present invention and simplify description, rather than indicate
Or imply that signified device or element must have a particular orientation, with the operation of specific orientation, therefore should not be understood as to this
The limitation of invention.
Embodiment 1
In the present embodiment, the present invention provides a kind of reading plotter for reading testing result, is used for read test element
Chemical examination test result, described device includes: the first light-emitting component 101 and the second light-emitting component 102, is respectively arranged at corresponding survey
The test section 403 and the position where control zone 405 for trying element, issue light and are irradiated to the corresponding region of testing element 40;The
One photodetector 201 and the second photodetector 202, are respectively arranged at pair of the first light-emitting component 101 and the second light-emitting component 102
Face, for receiving the reflection light from 40 corresponding region of testing element;Blocking element 30, for guiding light-emitting component to send out
The path of light out and/or the light from testing element will separate in independent space in two photodetectors
(Fig. 1).
In the present embodiment, the first light-emitting component 101 and the second light-emitting component 102 are light emitting diode, specially LED
Lamp, the first photodetector 201 and the second photodetector 202 are photodiode (PD), for detecting the light being irradiated to thereon,
And it is converted into the electric signal that can be detected.
In the present embodiment, first light-emitting component 101 and the second linearly arrangement of light-emitting component 102, it is described
The first photodetector 201 and the linearly arrangement, and the first light-emitting component 101 and the first light detection of the second photodetector 202
The linear arrangement respectively of device 201, the second light-emitting component 102 and the second photodetector 202.
In the present embodiment, have on the blocking element for separating the first light detection 201 and allow the survey from testing element
The notch 50 that the light in area 403 penetrates is tried, the position where the test section 403 of corresponding testing element, packet is arranged in the notch 50
The first notch 501 and the second notch 502 are included, first notch 501 is connected with the second notch 502;Separating the inspection of the second light
Surveying has the notch 50 for allowing the light of the control zone 405 from testing element to penetrate on the blocking element of device 202, the notch 50 is set
It sets and is lacked in the position where the control zone 405 of corresponding testing element, including the first notch 501 and the second notch 502, described first
Mouth 501 is connected with the second notch 502.
Wherein, including the first light-blocking member 301, third light-blocking member 303, fourth gear light component 304 and fifth gear light portion
First photodetector 201 is enclosed in independent space by the blocking element of part 305, has the on the first light-blocking member 301
One notch 501, first notch 501 are slope surface adjacent to the face of the first light-emitting component 101 and the first photodetector 102,
There is the second notch 502, first notch 501 and second lacks between fourth gear light component 304 and fifth gear light component 305
The width of mouth 502 is equal, so that a L-type notch 50 is formed on the blocking element for enclosing the first photodetector 201, so that the
The light that one light-emitting component 101 issues as much as possible can be irradiated to test section 403, but also the luminous energy from test section 403
Enough enter the first photodetector 201, the invalid light of test section near zone is effectively avoided to enter the first photodetector 201.Wherein,
Light-blocking member including sixth gear light component 306, the 8th light-blocking member 308, the 9th light-blocking member 309 and the tenth light-blocking member 310
Second photodetector 202 is enclosed in independent space by part, has the first notch 501 on sixth gear light component 306, described
The first notch 501 adjacent to the face of the second light-emitting component 102 and the second photodetector 202 be slope surface, in the 9th light-blocking member 309
And the tenth have the second notch 502, the width phase of first notch 501 and the second notch 502 between light-blocking member 310
Deng so that a L-type notch 50 is formed on the blocking element for enclosing the second photodetector 202, so that the second light-emitting component 102
The light of sending as much as possible can be irradiated to control zone 405, but also the light from control zone 405 is able to enter the inspection of the second light
Device 202 is surveyed, the invalid light of control zone near zone is effectively avoided to enter the second photodetector 202.Optimized by above-mentioned light path
Define light path and photoirradiated surface product, effectively further to improve the sensitivity and accuracy of testing result.
In the present embodiment, when testing element 40 is fixed on electronic reading out device, the fourth gear light portion
Part 304, fifth gear light component 305, the 9th light-blocking member 309 and the tenth light-blocking member 310 are contacted with testing element 40, and with survey
It is parallel in longitudinal direction to try element 40, the first light-blocking member 301, third light-blocking member 303, sixth gear optical element 306 and the 8th are light-blocking
Longitudinal extend of component 308 is intersected with testing element 40.
In the present embodiment, the electronic reading out device further includes third photodetector 203, the third light inspection
Device 203 is surveyed between the first light-emitting component 101 and the second light-emitting component 102, and is shone with the first light-emitting component 101 and second
Element 102 linearly arranges, for carrying out initial calibration or light modulation to electronic reading out device.
In the present embodiment, described device includes lateral flow testing element 40, as described above, testing element 40 can be with
It is to introduce the individual equipment of reading plotter to carry out analyte quality detection or testing element 40 is reading plotter
Inalienable part.If testing element is the indivisible component part of the reading plotter, which may include one
A testing element 40 for being able to carry out microfluid detection or lateral chromatography detection.
In the present embodiment, which is inserted into reading plotter including one with accommodating testing element 40
Slit or other openings, the shape and size of slit or opening, to allow a testing element 40 only can be in direction appropriate
It is successively inserted into.
In the present embodiment, which includes a processor, for receiving electric signal and being analyzed
And result judgement.Processor, which controls two light-emitting components and successively shines, irradiates detection zone 403 and the control zone of testing element 40
405, the first photodetector and the second photodetector successively receive the reflection light from test section 403 and control zone 405 and turn
Electric signal is turned to, the electric signal that processor receives photodetector carries out reading and analysis processing.
In the present embodiment, which further includes a display 130 and power supply component 140.Processor
Processing result is shown on the display 130, to facilitate observation testing result.Power supply component 140 is used for entire Photoelectric Detection
System power supply can use such as button cell power supply component (Fig. 7).
In the present embodiment, which further includes a buzzer 150, for prompting detection procedure or detection knot
Fruit.
In the present embodiment, the reading plotter includes substrate 60 and pedestal 70, wherein light-emitting component and photodetector
On substrate 60, substrate 60 is the board structure of circuit of strip, such as pcb board.There is a detection window on pedestal 70
701, the blocking element is located in detection window 701.In a specific embodiment, above-mentioned blocking element 30 is located at inspection
It surveys in window 701, wherein above-mentioned fifth gear light component 305 and the tenth light-blocking member 310 can be and be connected to detection window 701
Individual components, a distance that is also possible to be extended internally by detection window 701 formed.Further, the blocking element
30 can be integrally formed (Fig. 2 and Fig. 5) with pedestal 70.
In the present embodiment, the processor is circuit system, the processor, display 130, power supply component
140 and buzzer 150 be set on substrate 60.
In the present embodiment, substrate 60 is located at the side of detection window 701, and testing element 40 is located at detection window 701
The other side, substrate 60 and pedestal 70 can be dismountable combination, when substrate 60 and pedestal 70 are combined, testing element
40 when being fixed on pedestal 70, and detection window 701 is by the first light-emitting component 101, the second light-emitting component 102, the first photodetector
201, one or more areas of the second photodetector 202, third photodetector 203 and testing element 40 be enclosed in one it is closed
Space in.At this point, the first light-blocking member 301, third light-blocking member 303, sixth gear light component 306 and the 8th light-blocking member
308 with the mounting plane of light-emitting component 101/102 and photodetector 201~203 is seamless abuts, by 101 He of the first light-emitting component
Second light-emitting component 102 is separated with the first photodetector 201 and the second photodetector 202 respectively, and by the first photodetector
201 and second photodetector 202 separate;Fourth gear light component 304, fifth gear light component 305, the 9th light-blocking member 309 and
Ten light-blocking members 310 with testing element 40 is seamless abuts, one or more areas of testing element 40 are covered, will preferably be located at and survey
The partial region before and after area is tried, and the partial region covering before and after control zone, on the one hand stops to shine
The illumination that element issues is mapped to the capped region, and another party stops the light from the coated region to enter photodetector.
Reflected light from testing element test section and control zone passes through notch respectively and is received by two photodetectors, and being converted into can quilt
The electric signal of processor detection.Herein, blocking element can execute additional function, such as suitably support testing element 40,
Testing element 40 and light-emitting component and/or photodetector is set to keep appropriately distance.
In the present embodiment, testing element 40 can be an individual component for introducing the reading plotter, test member
Part 40 is fixed in the card slot 702 on pedestal 70.In the present embodiment, testing element 40 is set close to one end of detection zone 403
Have and inhales lining bar 110.Inhaling lining bar 110 is that common flow over inhales lining bar, and the sample absorbance area 401 of one end and testing element 40 connects
It connects, i.e. the sample absorbance area 401 of testing element 40, which is overlapped on, inhales on lining bar 110, and the other end is for contacting sample (Fig. 7).Inhale sample
Stick 110 is fixed in the groove 703 for being set to 70 one end of pedestal, the card slot 702 of the groove 703 and connecting test element 40
Not on a horizontal plane, the position of groove 703 is lower than card slot 702, when suction lining bar 110 is fixed in groove 703, the suction
Lining bar 110 is substantially flushed with testing element 40 or with the card slot 702 for placing testing element.The groove 703 is inhaled for contacting
There is a protrusion 704, which, which can be inserted into, inhales lining bar 110, plays the fixed work for inhaling lining bar 110 on the surface of lining bar 110
With (Fig. 1).When in use, using the absorption sample of lining bar 110 is inhaled, sample is flowed via testing element 40 to be transmitted.
In the present embodiment, which has conducting device, and the conducting device is for activating or waking up reading
Counting apparatus.The conducting device is front end conduction electrode 120, and one end of the front end conduction electrode 120 and suction lining bar 110 connect
It connects, the other end connects the preceding electrode contact blade of reading plotter turning circuit.In the present embodiment, the front end conduction electrode
120 be two.In the present embodiment, front end conduction electrode 120 is set in the fixed groove 703 for inhaling lining bar 110, with suction sample
Stick 110 is in contact.Specifically, the front end conduction electrode 120 is located at groove 703 and inhales between lining bar 110, inhales lining bar 110 and inhale
After sampling originally, when liquid flow is through front end conduction electrode 120, then detection system is switched on, and equipment starts to carry out self-test.Front end is led
Energization pole 120, which is set to groove 703 and inhales, can guarantee front end conduction electrode 120 and inhale the good of lining bar 110 between lining bar 110
Contact, because in use, certain displacement may be occurred because of collision or misoperation by inhaling lining bar 110, so that front end
Conduction electrode 120 cannot be contacted effectively with lining bar 110 is inhaled, and the device of the invention can be effectively prevent because of front end conduction electrode 120
With inhaling device can not be connected or can not activated caused by 110 poor contact of lining bar.
In the present embodiment, the electronic reading out device can also include a shell.The function of shell is simultaneously
It supports the component of reading plotter, and/or protects them from the influence of external environment.The shell can be such as poly- with carbonized plastic
Styrene or ABS (acrylonitrile-butadiene-styrene (ABS)) form optimal shape.Shell includes upper housing 80, lower case 90 and lid
Body 100.Upper housing 80, lower case 90 and the cooperation of lid 100 constitute hollow shell.In the present embodiment, upper housing 80, under
Shell 90, lid 100 are removably combined by buckle, can be convenient assembling.There is a window on upper housing 80,
For observing testing result.The structure of shell is without being limited thereto, upper housing 80, lower case 90, the detachable combination of lid 100
It is also not necessarily limited to buckle, such as the modes such as screw are adapted to the present invention.It is exposed by the opening of shell one end to inhale lining bar 110, it can be with
Facilitate pipette samples.
The reading plotter is in low energy consumption dormant state when unused, with suction 110 pipette samples of lining bar, fluid sample stream
Premenstrual termination electrode 120 turns it on, and reading plotter is activated.The device can about be waken up activation in 5-15 seconds, open immediately
Begin to carry out self-test, checks calibration parameter.
In a specific embodiment, (this is for a period of time after sample is added to 40 the preceding paragraph time of testing element
Refer to pre-set on analyte and testing element in sample can react with the analyte in sample
The reaction time for detecting substance, in general, this is 5-10 minutes for a period of time), processor controls two according to timing Design respectively
Light-emitting component alternately shines, and is respectively radiated to the test section 403 and control zone 405 of testing element, this receives the region of light
Light is reflected, reflected light by notch 50 be respectively radiated on photodetector 201 and photodetector 202 on.Photodetector 201
Corresponding electric signal or voltage are detected respectively with photodetector 202, and feedback detection information is to processor, and processor is according to being received
Detection information analyzed and determined.
Electronic reading out device of the invention provides a kind of preferable optical circuit path between light-emitting component and photodetector,
It obtains light intensity signal, the decision content for judging to compare is converted to by processor.The reading plotter of this optical path optimization can be used
In on other similar wide spectrum detection device.
In the case where lacking any element specifically disclosed herein, limitation, may be implemented illustrated and described herein
Invention.Used terms and expressions method is used as the term of explanation rather than limits, and is not intended in these terms and table
Up to any equivalent for excluding shown and described feature or part thereof in the use of method, and it should be realized that various remodeling exist
It is all feasible in the scope of the present invention.It is therefore to be understood that although specifically being disclosed by various embodiments and optional feature
The present invention, but the modifications and variations of concept as described herein can be used by those of ordinary skill in the art, and recognize
It is fallen into for these modifications and variations within the scope of the present invention of the appended claims restriction.
It is described herein or record article, patent, patent application and every other document and can electronically obtain
The content of information to a certain extent in full include herein by reference, just as each individual publication by specific and single
Solely point out by reference.Applicant retains from any of any this article, patent, patent application or other documents
And all material and information are incorporated into the right in the application.
Claims (15)
1. a kind of electronic reading out device, the chemical examination test result on read test element, described device include:
At least two photodetectors, including the first photodetector and the second photodetector, it is corresponding from testing element for receiving
The reflection light in region, which is characterized in that one at least two photodetectors is isolated in independent space.
2. electronic reading out device according to claim 1, which is characterized in that light-blocking around photodetector by being enclosed in
Element separates at least one photodetector in independent space.
3. electronic reading out device according to claim 2, which is characterized in that have to allow on the blocking element and carry out self-test
The notch that the light of element penetrates.
4. electronic reading out device according to claim 3, which is characterized in that the notch is set to corresponding testing element
Position where test section or control zone.
5. electronic reading out device according to claim 3, which is characterized in that the notch includes the first notch and/or the
Two notches.
6. electronic reading out device according to claim 3, which is characterized in that the blocking element includes for separating light inspection
The first light-blocking member of device and light-emitting component is surveyed, there is the first notch on first light-blocking member.
7. electronic reading out device according to claim 6, which is characterized in that first notch is inclined notch.
8. electronic reading out device according to claim 3, which is characterized in that the blocking element further comprises for dividing
Every on the second light-blocking member of photodetector and testing element, second light-blocking member have the second notch.
9. electronic reading out device according to claim 8, which is characterized in that second notch is connected with the first notch
It is logical.
10. electronic reading out device according to claim 3, which is characterized in that the blocking element further comprises being used for
Separate the third light-blocking member of at least two photodetector, does not have notch on the third light-blocking member.
11. electronic reading out device according to claim 1, which is characterized in that described device further includes light-emitting component, described
The light-emitting component test section that is set to corresponding testing element or the position where control zone.
12. electronic reading out device according to claim 11, which is characterized in that the light-emitting component at least two,
Do not have blocking element between at least two light-emitting components.
13. electronic reading out device according to claim 12, which is characterized in that between at least two light-emitting components
It further include third photodetector.
14. electronic reading out device according to claim 13, which is characterized in that at least two light-emitting components and/
Or third photodetector linearly arranges.
15. electronic reading out device according to claim 1, which is characterized in that the electronic reading out device further includes cross
It include test section and control zone on the testing element to flowing test element.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910269927.8A CN110057819A (en) | 2019-04-04 | 2019-04-04 | A kind of electronic reading out device |
AU2019206031A AU2019206031A1 (en) | 2019-01-10 | 2019-07-17 | Reading apparatus |
US16/517,027 US11525773B2 (en) | 2019-01-10 | 2019-07-19 | Reading apparatus |
EP19194038.6A EP3680646A1 (en) | 2019-01-10 | 2019-08-28 | Reading apparatus |
US17/985,437 US11860085B2 (en) | 2019-01-10 | 2022-11-11 | Reading apparatus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910269927.8A CN110057819A (en) | 2019-04-04 | 2019-04-04 | A kind of electronic reading out device |
Publications (1)
Publication Number | Publication Date |
---|---|
CN110057819A true CN110057819A (en) | 2019-07-26 |
Family
ID=67318257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910269927.8A Pending CN110057819A (en) | 2019-01-10 | 2019-04-04 | A kind of electronic reading out device |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN110057819A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114486866A (en) * | 2020-10-23 | 2022-05-13 | 浙江东方基因生物制品股份有限公司 | Device for displaying liquid sample detection result by visual symbol |
US20230077363A1 (en) * | 2019-01-10 | 2023-03-16 | Zhejiang Orient Gene Biotech Co., LTD | Reading Apparatus |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1174996A (en) * | 1996-07-16 | 1998-03-04 | 曼海姆泊灵格股份公司 | Analysis system for testing small volume sample |
US20050237531A1 (en) * | 2004-03-05 | 2005-10-27 | Roman Juan F | Miniature optical readhead for optical diagnostic device |
CN1948952A (en) * | 2005-10-12 | 2007-04-18 | 安捷伦科技有限公司 | Semi-disposable optoelectronic rapid diagnostic test system |
EP2031376A2 (en) * | 2007-09-01 | 2009-03-04 | Inverness Medical Switzerland GmbH | Assay device with shared zones |
US20110184651A1 (en) * | 2010-01-26 | 2011-07-28 | Shih-Yi Weng | Electronic assay apparatus and method thereof |
CN102323215A (en) * | 2011-08-05 | 2012-01-18 | 广州万孚生物技术有限公司 | Analyzing and reading device and method |
CN202486051U (en) * | 2011-11-17 | 2012-10-10 | 艾博生物医药(杭州)有限公司 | Equipment for reading test result on test carrier |
CN103115899A (en) * | 2011-11-17 | 2013-05-22 | 艾博生物医药(杭州)有限公司 | Device for reading test results on test carrier |
CN104730229A (en) * | 2015-03-27 | 2015-06-24 | 广州万孚生物技术股份有限公司 | Electronic detection device |
CN210142078U (en) * | 2019-04-04 | 2020-03-13 | 浙江东方基因生物制品股份有限公司 | Electronic reading device |
-
2019
- 2019-04-04 CN CN201910269927.8A patent/CN110057819A/en active Pending
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1174996A (en) * | 1996-07-16 | 1998-03-04 | 曼海姆泊灵格股份公司 | Analysis system for testing small volume sample |
US20050237531A1 (en) * | 2004-03-05 | 2005-10-27 | Roman Juan F | Miniature optical readhead for optical diagnostic device |
CN1948952A (en) * | 2005-10-12 | 2007-04-18 | 安捷伦科技有限公司 | Semi-disposable optoelectronic rapid diagnostic test system |
EP2031376A2 (en) * | 2007-09-01 | 2009-03-04 | Inverness Medical Switzerland GmbH | Assay device with shared zones |
US20110184651A1 (en) * | 2010-01-26 | 2011-07-28 | Shih-Yi Weng | Electronic assay apparatus and method thereof |
CN102323215A (en) * | 2011-08-05 | 2012-01-18 | 广州万孚生物技术有限公司 | Analyzing and reading device and method |
CN202486051U (en) * | 2011-11-17 | 2012-10-10 | 艾博生物医药(杭州)有限公司 | Equipment for reading test result on test carrier |
CN103115899A (en) * | 2011-11-17 | 2013-05-22 | 艾博生物医药(杭州)有限公司 | Device for reading test results on test carrier |
CN104730229A (en) * | 2015-03-27 | 2015-06-24 | 广州万孚生物技术股份有限公司 | Electronic detection device |
CN210142078U (en) * | 2019-04-04 | 2020-03-13 | 浙江东方基因生物制品股份有限公司 | Electronic reading device |
Non-Patent Citations (2)
Title |
---|
刘军涛;郭宗慧;刘春秀;岳伟伟;周爱玉;蔡新霞;: "免疫层析试条量化检测系统研究", 微纳电子技术, no. 1, 15 August 2007 (2007-08-15), pages 379 - 382 * |
王洋;蒋凯;王萍;韩纪昱;: "基于光源调制技术的金标试纸条定量分析仪器", 电子技术应用, no. 12, 6 December 2012 (2012-12-06), pages 17 - 19 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20230077363A1 (en) * | 2019-01-10 | 2023-03-16 | Zhejiang Orient Gene Biotech Co., LTD | Reading Apparatus |
US11860085B2 (en) * | 2019-01-10 | 2024-01-02 | Zhejiang Orient Gene Biotech Co., LTD | Reading apparatus |
CN114486866A (en) * | 2020-10-23 | 2022-05-13 | 浙江东方基因生物制品股份有限公司 | Device for displaying liquid sample detection result by visual symbol |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11802882B2 (en) | Methods for the detection of analytes in small-volume blood samples | |
ES2291530T3 (en) | READING DEVICE, METHOD AND SYSTEM TO PERFORM SIDE FLOW TESTS. | |
CN104471384A (en) | Clinical diagnostic systems | |
CN106716137A (en) | Joint spectroscopic and biosensor system for point-of-care testing | |
JP2007511770A (en) | Sample collection cup with integrated sample analysis system | |
US20150118689A1 (en) | Systems and methods for whole blood assays | |
CN101533014A (en) | Colloidal gold chromatography test paper strip for quickly detecting bisphenol A and preparation method thereof | |
CN110057819A (en) | A kind of electronic reading out device | |
CN101545864A (en) | Optical analysis reading device | |
CN201210144Y (en) | Optical analysis reading device | |
CN112326974A (en) | Detection device | |
US20230087999A1 (en) | Test device | |
CN108802018A (en) | A kind of manufacturing method for the method and detection device that can intuitively read testing result | |
CN207751883U (en) | A kind of sample testing apparatus | |
US11860085B2 (en) | Reading apparatus | |
CN210090318U (en) | Reading device and reading device for reading detection result | |
CN209269717U (en) | The detection device of analyte in sample | |
KR101635956B1 (en) | Diagnostic kit having puncturing element | |
CN107874767A (en) | The device of analyte in a kind of detection sample | |
CN111426684A (en) | Reading device | |
CN207882276U (en) | A kind of detection device with solution storage device | |
CN209269716U (en) | Integrated sample collecting and detecting device | |
CN210166298U (en) | Information acquisition device for dry chemical analysis and immunological analysis | |
US20230128976A1 (en) | Device for testing a analyte in a liquid sample | |
CN209107366U (en) | A kind of detection device with hemostix |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |