CN103115899A - Device for reading test results on test carrier - Google Patents
Device for reading test results on test carrier Download PDFInfo
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- CN103115899A CN103115899A CN2011103664462A CN201110366446A CN103115899A CN 103115899 A CN103115899 A CN 103115899A CN 2011103664462 A CN2011103664462 A CN 2011103664462A CN 201110366446 A CN201110366446 A CN 201110366446A CN 103115899 A CN103115899 A CN 103115899A
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Abstract
The invention provides a device for reading test results on a test carrier. The device comprises the test carrier, at least one light-emitting component, at least one photodetector and a light baffling component, wherein the at least one light-emitting component is used for emitting light and enabling the light to be irradiated onto corresponding one or more corresponding area on the test carrier; the at least one photodetector is used for detecting light emitted by the one or the more area on the test carrier; and the light baffling component is capable of preventing outside light from entering the device. According to the device provided by the invention, the detection can not be interfered, and the detection precision can be improved. Meanwhile, the device further comprises a light path conduction structure for preferably conducting light rays, so that the detection accuracy of the device can be further improved; and after an unloaded form is adopted, the device can be used for detecting for a plurality of times, so that the utilization rate of the device is improved, and the device is easily operated by an operator.
Description
Technical field
Theme disclosed by the invention relates to the equipment that reads by chemical examination object measured value.Especially, it relates to figure reading electronic device, uses together with the chemical examination test piece of using measuring method.
Background technology
Can buy in the market the multiple family that is suitable for and use the analytical equipment that the chemical examination thing is tested.Unipath just sells the crossing current immunoassay device of a kind of suitable measurement conceived hormone human body chorion (hCG) under the CLEARBLUE trade (brand) name, this equipment is open in EP291194.
Particularly, EP291194 discloses a kind of immunoassay device, comprising: the test carrier of a porous infiltration, and this carrier comprises the particular combination reagent of chemically examining the particulate mark of thing for a kind of, and under dampness, this reagent can move freely; With a kind of particular combination reagent of the not tape label for same chemical examination thing, this reagent is fixed in the test section or test section in specific adhesive agent downstream of described not tape label.Suspect that the liquid sample that contains described chemical examination thing is applied to the carrier of described porous infiltration, should chemically examine the particular combination reagent effect of thing and described particulate mark thereon, form a kind of complex of chemically examining thing-combination.Described particulate mark is coloured, normally golden or dyeing condensate, for example, latex or poly-inferior peace fat.Described complex moves into the test section subsequently, consists of another mesocomplex at the particular combination reagent of test section and described fixing not tape label, makes the existence range of described chemical examination thing detected or observe.
With electronics reader and test carrier, analytical test strip for example, the concentration and/or the amount that combine in order to analyte in the test fluid sample are known technologies, for example Chinese patent 200410045273.4; 200410045275.3; 200410063910.0 described such.General, as to send from light source such as light emitting diode irradiation test-strips, and with photodetector detection of reflected light or transmitted light.Typically, this reader contains a light emitting diode at least, and each light emitting diode is provided with corresponding photodetector.
Above disclosed device and concrete product are implemented out, in these equipment, test-strips all with fetch equipment prior assembled being fixed together all, position between test-strips and fetch equipment is producing, transportation, sell and test, and test all is in a relatively-stationary state after finishing, between them without any change.Such structure mainly applies in the early pregnancy detection at present, and the user only need to be drenched urine on the suction sheet of proving installation, just directly can wait result to be tested.Along with the continuous demand of consumer to this series products, to wish at all to apply to such detection in other detection, this just need to provide some different fetch equipments to satisfy growing market demand.Such as: need an equipment can carry out the detection of a plurality of samples, perhaps, test result is more accurate etc.
Summary of the invention
In order to solve above problems, the invention provides the equipment of test result on a kind of read test carrier, it comprises at least one light-emitting component, sends light and shines on test carrier in corresponding one or more districts; At least one photodetector is for detection of the light that sends the one or more districts from described test carrier; With the element that is in the light, this element that is in the light can stop that extraneous light enters in this equipment.
In the present invention, the element that is in the light can stop extraneous light to enter into equipment of the present invention, concrete, when test carrier is positioned at equipment, this element that is in the light can stop light shine on test carrier certain or some the zone or whole test carrier, further, also can stop light to shine photodetector and the light-emitting component that is positioned at equally on equipment.For guarantee extraneous light do not shine on test carrier certain or some the zone or whole test carrier, this element that is in the light surrounds certain or some zones or the whole test carrier of test carrier, makes extraneous light can't enter into certain or some zone or whole test carrier on test carrier; And this element that is in the light also surrounds light-emitting component and photodetector, makes extraneous light also can't shine this two kinds of elements.On the other hand, this element that is in the light surrounds certain or some zone of test carrier or whole test carrier and light-emitting component and photodetector, the light that light-emitting component is sent is blocked in certain zone, and is preferred, on the test zone of test carrier; And, make photodetector can receive only the light that sends on test carrier.More specifically, this element that is in the light makes certain or some zone of test carrier and light-emitting component and photodetector in the space of a relative closure, and the light outside this space can't enter in this space; And the light in this space also can only transmit in this space.
This element that is in the light can be made of complete parts, also can be formed by a plurality of component combinations, and it can be positioned at the outside or inner of present device.The material of this element that is in the light is not limit, as long as possess the function that can stop light, preferred, the material of the element that is in the light is identical with equipment material.In a specific embodiment, this be in the light element and equipment are lighttight plastics and make.
In an embodiment, test carrier coordinates with this equipment with the form that can unload." can unload " and can be here, when also not detecting, can allow test carrier and fetch equipment separately, when needs detect, allow test carrier be combined with fetch equipment, in conjunction with time can be that test carrier is applied in before sample or afterwards, allow test result on fetch equipment read test carrier.Perhaps, the form of " can unload " can also be, after detection is completed, can also isolate test carrier from fetch equipment, carries out reading for test result on the next test carrier of same sample or different samples.Allow like this result of fetch equipment on can continuous several times read test carrier, more save cost and be conducive to environmental protection.Even, can use different material in this equipment Inspection sample that can unload.
In preferred mode, the element that is in the light is comprised of two parts at least, this at least two parts be in the light and coordinate with the form that can unload between element.In an embodiment, the element that is in the light of the part in two parts is positioned on equipment at least, and the element that is in the light of the another part in two parts is positioned on test carrier at least.In preferred embodiment, another part element that is in the light is positioned on the test zone of test carrier.Perhaps, in selectable embodiment, another part element that is in the light also is positioned at the detection control area of test carrier or/and on the reference zone.
In an embodiment, be positioned at a part on equipment element and another part on being positioned at test carrier element that is in the light that is in the light and coordinate to form and to stop that external light source enters test zone and/or reference zone on test carrier and/or detects the structure of control area.
When test carrier when this equipment is combined with the form that can unload, this element that is in the light can be divided into two parts at least, wherein a part is arranged in equipment, enclose and seal light-emitting component and photodetector, and another part element that is in the light is positioned on certain or some zones or whole test carrier of test carrier, is used for enclosing all or part of zone on test carrier.The two parts of element of being in the light are also to coordinate with the form that can unload, and forming when these two parts are combined together can airtight test carrier, and the space of light-emitting component and photodetector stops that extraneous light enters in the space of this element that is in the light.
In another preferred mode, test carrier is arranged in a housing, and the element that is in the light of the another part in two parts is positioned on this housing at least.Preferably, housing comprises the window corresponding with the test carrier subregion, and wherein, the element that is in the light of the another part in two parts is positioned on this window at least.In more preferred mode, the element that is in the light of the another part in two parts is divided at least two parts to window at least.Optionally, the element that is in the light of the another part in two parts is divided into window test zone and detects the control area at least.Again or, the element that is in the light of the another part in two parts is divided into window test zone, reference zone and detects the control area at least.Further in mode, when the housing that test carrier is arranged is inserted in this equipment, is positioned at a part on equipment element and another part on being positioned at housing element that is in the light that is in the light and coordinates to form and to stop that extraneous veiling glare enters the structure of window.
When but test carrier coordinated for unload-type with equipment, its advantage was the sample that can utilize on a plurality of test carriers of testing of equipment, more convenient operation.But also to consider some problems: wish that at first previous test-strips does not cause any pollution to afterwards test-strips, also wish in addition to avoid during insertion some mechanical parts on equipment to cause infringement to the test carrier structure; And to causing damage or loss of function through accurate some the chemical reagent of anticipating on carrier of processing, because these destructions can be caused the invalid or inaccurate of test result.Simultaneously, the cooperation position of wishing carrier and fetch equipment is relative fixing, and the precision that cooperatively interacts, so just may not affect the result that finally reads, the result that reads like this is more accurate, when adopting simultaneously different test carriers that same sample is repeatedly tested, the result of acquisition is more consistent, and error is controlled in tolerance interval.Increase a housing at test carrier, just can avoid these above-mentioned problems.When patching with the test carrier of housing and checkout equipment, originally directly contacted with equipment by test carrier and the equipment housing that changes on test carrier that directly contacts.Housing directly contacts with checkout equipment, does not affect the test carrier that is positioned at enclosure interior, simultaneously, has also avoided the sample of test carrier can touch checkout equipment, can not affect the detection of next test carrier.Therefore, increase a housing on test carrier, be very important in this equipment that can unload, this service life of equipment is increased, can also increase accuracy and the accuracy of detection.
Further, the another part that originally was positioned at the element that is in the light on test carrier changes to and is positioned on this housing.But the element that is in the light on this housing coordinates for unload-type with the element that is in the light on being positioned at equipment, in the test carrier interventional instrument with housing, the two-part element that is in the light coordinates certain or some zone of test carrier or whole test carrier is enclosed in the element that is in the light, and makes it not be subject to the irradiation of extraneous light.
Some preferred embodiment in, the element that partly is in the light forms the conducting light paths structure, the light that light-emitting component sends can be shone on test carrier for this conducting light paths structure, allows simultaneously the light that sends in one or more districts on test carrier be received by photodetector.
In preferred mode, this conducting light paths structure is divided into two parts, coordinates with the form that can unload between two parts.
Be in the light some or a certain zone of element with test carrier, as: test zone, and/or reference is regional, and/or control area, be enclosed in the space of a sealing with light-emitting component and photodetector, make its interference that is not subjected to extraneous light, simultaneously, also guaranteed taking full advantage of of internal illumination element light.Preferred, the space segmentation that the parts of the element that is in the light will seal is one or more conducting light paths structures.The conducting light paths structure makes certain or some zone of test carrier and light-emitting component and photodetector in the space of a relative closure, and the light outside this space can't enter in this space; And the light in this space also can only transmit in this space, light in this space is utilized effectively more fully, and make the light that receives light-emitting component of test carrier energy optimization (maximum), reduce light as far as possible and shine other zones; And the light that sends (reflection) from test carrier also can fully be received by photodetector; And this conducting light paths structure can be avoided mirror-reflection fully.Namely this conducting light paths structure light that light-emitting component is sent has certain path channels, and the light that photodetector is received has certain scope; The light that also namely light-emitting component is sent is blocked in certain zone, such as, on the test zone of test carrier; And, make photodetector can receive only the light that sends on test carrier.
One preferred embodiment in, the part of this two parts conducting light paths structure is positioned on equipment, and another part of this two-part conducting light paths structure is positioned on test carrier.In another optimal way, test carrier is arranged in a housing, and this housing comprises the window corresponding with the test carrier subregion, and another part of two parts conducting light paths structure is positioned on the window of this housing.
Lay respectively on equipment and the shell window of test carrier on the cooperation of two parts conducting light paths structure for unloading, when both combining, can be with light-emitting component, the window of photodetector and housing and the subregion of the test carrier under window are included in whole conducting light paths structure, make the luminous energy that light-emitting component sends arrive certain subregion of test carrier according to certain passage, and make the light of this subregion arrive photodetector by certain passage.
In an embodiment, at least one light-emitting component comprises three light-emitting components, and at least one photodetector comprises three photodetectors.
In another embodiment, the element that is in the light forms three conducting light paths structures.
In a preferred embodiment, three light-emitting components, three photodetectors and three conducting light paths elements are one-to-one relationship, i.e. light-emitting component, photodetector and conducting light paths structure form a conducting light paths system.More specifically in embodiment, each conducting light paths system is corresponding to the test zone of test carrier, or the reference zone, or the control area.More specifically in embodiment, the test zone of the corresponding test carrier of the first light-emitting component, and corresponding with the first photodetector, be positioned at the first conducting light paths structure; And, the reference zone of the corresponding test carrier of the second light-emitting component, and corresponding with the second photodetector, be positioned at the second conducting light paths structure; And, the control area of the corresponding test carrier of the 3rd light-emitting component, and corresponding with the 3rd photodetector, be positioned at the 3rd conducting light paths structure.
Be surrounded by a zone of a light-emitting component and photodetector and test carrier in this each conducting light paths structure, shine the test section of test carrier such as a light-emitting component, light by the test section reflection shines a photodetector again, and this three is in same conducting light paths structure.Same, the illumination that another light-emitting component sends is mapped to the reference region of test carrier, then reflexes to another photodetector by reference region, and this three is in another conducting light paths structure.Have, the 3rd illumination that light-emitting component sends is mapped to the control zone of test carrier again, then reflexes to the 3rd photodetector by the control zone, and this three is positioned at the 3rd conducting light paths structure.Form a path channels in each conducting light paths structure.
Specifically, a light-emitting component, test zone and the corresponding sensitivity that improves detection of photodetector.The device that utilizes optical detection that some are traditional utilizes the corresponding test of a photodetector to need to detect the structure of light more than one usually, such as, a photodetector detects the light that send in a plurality of zones, and perhaps, a photodetector detects the light that is sent by a plurality of light-emitting components.Like this, can there be data cross between regional and/or the situation of interference, thereby the slow or coarse situation of result of detection reaction occur, the inaccurate situation of testing result is even arranged.In the present invention, the three is corresponding one by one, provides special element to carry out corresponding detection, can improve sensitivity and the degree of accuracy of detection.
Another preferred embodiment in, three photodetectors are respectively in the both sides of light-emitting component.Photodetector is respectively in light-emitting component both sides, can make between each photodetector and maintain a certain distance, and can guarantee that each photodetector and light-emitting component are nearest, avoided photodetector to receive the light of other light-emitting component and produced interference, impact detects accuracy and the accuracy of reading.
In embodiment, comprise one to one another parts that are in the light between light-emitting component and photodetector more specifically, this another be in the light parts will be one to one light-emitting component and photodetector separation.This another element that is in the light can stop that the light of light-emitting component shines directly into photodetector, avoids the impact on the data on photodetector read test carrier.
In some preferred specific embodiments, in each conducting light paths system, the face that is positioned at the conducting light paths structure adjacent light detecting device on equipment is domatic; The face that is positioned at the conducting light paths structure adjacent light detecting device on housing is vertical plane.Conducting light paths structure on the housing of this adjacent light detecting device is by the common domatic vertical plane that changes into, and the light that can avoid light-emitting component to send shines directly into the mirror-reflection of the domatic rear formation of the conducting light paths structure on this original housing; After light shines on present vertical plane simultaneously, through reflection, light arrives the zone of the needs irradiation on test carrier, thereby increased amount of light and the intensity of light reflection to the test carrier in this conducting light paths structure, can further improve the display effect as a result of test zone on test carrier.
In other preferred embodiments, in each conducting light paths system, two parts of the conducting light paths structure of contiguous light-emitting component are positioned at part on housing than being positioned at part on equipment away from light-emitting component not on same vertical plane.After light-emitting component emits beam, have the part light emission to each face of this conducting light paths structure, and reflect.The face of contiguous light-emitting component also can receive light and reflect, and the light great majority of reflection can shine directly on photodetector, and the conducting light paths structure on housing is after light-emitting component, forming a groove on test carrier and equipment between the light path conducting structure, after the light arrival groove that light-emitting component sends, can reflex on test carrier through recess sidewall, like this, both reduced the light that does not shine on test carrier and directly reflexed on photodetector, and increased again light simultaneously and incide on test carrier.
In some embodiment, test carrier is porous carrier.
In some embodiments, this equipment also comprises optical access system.
Beneficial effect
Fetch equipment of the present invention can make and detect without interruption, increase the precision that detects, simultaneously, also comprise and make the conducting light paths structure that light can better conducting, the accuracy and precision of this equipment Inspection is further increased, simultaneously, take the form that can unload, make this equipment can carry out repeatedly detection, increase plant factor and also the operator is more easily operated.
Description of drawings
Fig. 1 is fetch equipment optical texture in an embodiment (conducting light paths structure) cross-sectional view;
Fig. 2 is optical texture (conducting light paths structure) cross-sectional view of fetch equipment in another embodiment of the present invention;
Fig. 3 is optical texture (conducting light paths structure) cross-sectional view of fetch equipment in another preferred implementation of the present invention;
Fig. 4 is the blast structural representation of fetch equipment in one embodiment of the present invention and the perspective view that includes the housing of test carrier;
Fig. 5 is the plan structure schematic diagram of one embodiment of the present invention middle shell;
Fig. 6 be in the light comprising of one embodiment of the present invention element fetch equipment look up structural representation;
Fig. 7 is the perspective view (the lower part that do not comprise test carrier and housing) (from top) of fetch equipment with shell combination time the in a specific embodiment of the present invention;
Fig. 8 is fetch equipment another perspective view (the lower part that does not comprise test carrier and housing) (from the below) with shell combination time the in a specific embodiment of the present invention;
Fig. 9 is that in a specific embodiment of the present invention, fetch equipment is looked up structural representation (the lower part that does not comprise test carrier and housing) with shell combination the time;
Figure 10 is the part structure for amplifying schematic top plan view that includes the fetch equipment of the element that is in the light;
Figure 11 is the vertical section structure schematic diagram (the lower part that does not comprise test carrier and housing) of the A-A` in Fig. 7;
Figure 12 is the cross-sectional view of the B-B` in Fig. 7;
Figure 13 is test zone on LED lamp and PD detecting device and test carrier in a specific embodiment of the present invention; Locus projection relation schematic diagram between reference area and testing result control area;
Figure 14 is light road schematic diagram in conducting light paths structure of the present invention;
Figure 15 is another light road schematic diagram in conducting light paths structure of the present invention.
Description of reference numerals
The optical texture of fetch equipment (conducting light paths structure) 100; The optical texture of another fetch equipment of the present invention (conducting light paths structure) 200,201; The present invention comprises the fetch equipment 400 of the element that is in the light; The fetch equipment 300 that comprises test carrier and housing; Light-emitting component 105; Photoelectric detector 103; LED lamp 51,52,53; PD detecting device 41,42,43; Conducting light paths structure (part of the element that is in the light) 101; Light path conducting structure on equipment (element is in the light on equipment) 202; Light path conducting structure on housing (element is in the light on housing) 203; Domatic 106 of conducting light paths structure; On equipment, the light path conducting structure domatic 2021; Light path conducting structure vertical plane 2031 on housing; The another side of light path conducting structure on equipment (near light-emitting component) 2022; The another side of light path conducting structure on housing (near light-emitting component) 2032; Test carrier 10; The film 120 of test carrier; Pcb board 102; Another parts 104,44 that are in the light, 45; The housing 30 that contains test carrier; Shell window 90,35,36,37; Housing groove 34; Sample interpolation place 31 on housing; Top shell component 71; Bottom shell component 72; Be affectedly bashful position 73; Housing side groove 32; On housing, alignment windows 33; Element 40 is in the light on equipment; The element 38,39 that is in the light on housing, 61,62; Element card article 406,407 is in the light on equipment; The alignment windows 47 of element is in the light on equipment; The window 401,402,403 that the element that is in the light on equipment is corresponding with shell window; The projection 404 that the element that is in the light on equipment is corresponding with housing groove 34; The element projection that is in the light on equipment (being used for laying light-emitting component and photodetector) 70; The projection 701,702,703,704 of interval light-emitting component; The projection 705,706,707,708,709 of interval light detecting device; The test zone 130 of test carrier, reference zone 140, control area 150; Element recess 48 is in the light; Indicate 74 on housing; Path channels structure 80; Part on housing 30 element 75,76 that is in the light; Groove area 85 in the conducting light paths structure.
Embodiment
In an embodiment of the invention, fetch equipment includes test carrier 10, at least one light-emitting component 105, at least one photodetector 103 and the element 101 that is in the light.
In an embodiment, test carrier comprises sample area, test section 130, control zone 150 and suction zones.In another embodiment, this test carrier comprises sample area, test section 130, reference region 140, control zone 150 and suction zones.Preferably, on the subregion on test carrier 10, can add film 120 and ooze out from the zone of test carrier to prevent unnecessary sample.
Light-emitting component 105 is used for emitting beam, such as various light sources.In an embodiment, this light-emitting component is the LED lamp.Light-emitting component 105 is one or more, such as, be 1, or 2, or 3,4 and above etc.
Photodetector 103 is used for detecting the light that shines on it, and in a specific embodiment, this photodetector is photodiode (PD detecting device).The quantity of photodetector 103 is also one or more, such as 1, or 2, or 3, and 4 and above etc.
In fetch equipment of the present invention, the as a whole element of the element 101 that is in the light consists of, and also can form for a plurality of component combinations.The subregion that this element 101 that is in the light can make light-emitting component 105 and the photodetector 103 in this fetch equipment 100 and be positioned at the test carrier 10 of fetch equipment is not subjected to irradiation and the interference of extraneous light.
On this fetch equipment 100, light-emitting component 105 and photodetector 103 can the position in the inner, test carrier 10 also can be positioned at fetch equipment, and it is inner or outside that the element 101 that is in the light can be positioned at this equipment 100, as long as can satisfy the function that stops extraneous light access arrangement inside.
The making material of this fetch equipment 300 is extensive, such as PP, and the materials such as PVC or plastics, in an embodiment, this reading device is that lighttight plastic material is made.The material of element of being in the light need to satisfy the function that is in the light, and other are not limit.This material can be identical or different with fetch equipment, and in a preferred concrete mode, the material that the element that is in the light uses is not lighttight plastic material also, and is identical with the fetch equipment material.
In a specific embodiment, (the detection material reaction time that can react with analyte in sample that this a period of time refers to settle in advance on analyte and test carrier in sample after sample is added on test carrier after a period of time, usually, this a period of time is 5-10 minute), light-emitting component is emitted beam, shine a certain on test carrier or some is regional, this zone that receives light is with light reflection, and reflected light shines on photodetector.Then, the light that reads by photodetector shows the result of the sample reaction that these are regional.
A fetch equipment of the present invention, as shown in Figure 1, it comprises at least one light-emitting component 105, sends light and shines on the film 120 of test carrier 10 or test carrier; At least one photoelectric detector 103, for detection of the light that sends the one or more districts from described test carrier 10, and the element 101 that is in the light, allow test carrier 10 and light-emitting component 105 be fixed together with photodetector 103 by this element 101 that is in the light, simultaneously rational layout can be completed smoothly the test result on test carrier 10 is read.Preferably, light-emitting component 105 and photoelectric detector 103 are positioned on pcb board 102.This fetch equipment 100 is that test carrier 10 and equipment 100 are fixed together, and after completing test, fetch equipment 100 and test carrier 10 abandon, and are disposable equipment.Such equipment causes the waste of resource and is unfavorable for environmental protection, and such equipment can not carry out repeatedly reading different test carriers in addition.
The fetch equipment 200 of another embodiment of the invention can make fetch equipment repeatedly use, and saves cost and cuts the waste.What the fetch equipment 200 of this optimization was different from last embodiment is that test carrier 10 is not what be fixed together with fetch equipment 200, but both is combining of unload-type.Here " can unload " can be understood as: first separate, then be in contact with one another and form parts of completing; Also can be understood as: complete two establishments of some functions in the situation that separately or incorrect position, these two assemblies can not realize becoming after these two assemblies combinations the function of assembly, only have to combine when two assemblies and could realize certain function.Concrete, this equipment 200 comprises at least one light-emitting component 105, sends light and shines on the film 120 of test carrier 10 or test carrier in corresponding one or more districts; At least one photodetector 103 is for detection of the light that sends the one or more districts from described test carrier 10; With the element 101 that is in the light, this element 101 that is in the light can stop in extraneous light access arrangement, even extraneous light can't shine the photodetector 103 in equipment, light-emitting component 105, test carrier 10; Wherein, test carrier 10 and the form combination of fetch equipment 200 for unloading.In order to coordinate the detachable of test carrier and fetch equipment, the element 101 that is in the light can form for two parts at least, wherein a part is positioned on equipment 202, another part is positioned on test carrier 203, be also both the unloading form to coordinate, as shown in Figure 2, when fetch equipment 200 did not have test result on read test carrier 10, the part 202 of the element that is in the light was separated and does not contact with another part 203 of the element that is in the light; When needs carry out read test as a result the time, allow test carrier 10 be inserted in fetch equipment 200, and the part 202 of the element that is in the light contacts with another part 203 of the element that is in the light and forms a complete element 101 that is in the light, and this moment, fetch equipment 200 was completed reading of test result on test carrier 10.For example, in Fig. 2, be in the light another part 203 of a part 202 and the element that is in the light of element when separating, due to the malposition that does not have test carrier or test carrier (with respect to light-emitting component 105, the position of photoelectric detector 103), can not correctly carry out reading of test result on test carrier, otherwise, can correctly carry out reading of test result.Certainly, the part 202 of the element that is in the light can be positioned on pcb board 102 on fetch equipment, and and light-emitting component 105, detecting device 103 is numbered C and exists together as another separate part; The another part 203 of element of being in the light can as parts together with test carrier 10, be numbered D, individualism.When needs carry out on test carrier 10 test result, after allowing two two different parts C that include the element that is in the light and D be coupled to suitable position, complete reading of whole test result.Certainly, the another part 203 of the part 202 of element and the element that is in the light of being in the light can also be positioned at fetch equipment other parts and or structure on, when also not carrying out the reading of test result on test carrier, these two parts separately, when need to read the test result on test carrier, allow two parts that before separated coordinate, allow test carrier and light-emitting component and tester be in suitable position, carry out reading of test result.
Fig. 4-13rd, the fetch equipment 300 of the integral body in a preferred embodiment of the present invention.
As shown in Figure 4, test carrier 10 is arranged in a housing 30, and housing 30 comprises two housing parts 71,72 in up and down, and they engage by the form of buckle or rivet, and test carrier 10 is positioned between the housing parts 71,72 of two of up and down and is fixed in housing 30.Like this, when the test carrier 10 with housing patches with fetch equipment, can avoid sample to touch fetch equipment, also can avoid test carrier damaged.Have on top shell component 71 and expose the subregional window 90 in test carrier top.Zone on the test carrier 10 that is exposed by window 90 can be test zone 130, one or several in reference zone 140 and control area 150.The shape of window 90 can design arbitrarily according to the shape that needs on test zone expose, and is generally rectangle, can certainly be for circular or oval.Window 90 can be the district that directly exposes on test carrier, also can be covered by transparent sheet (film) 120, be not mapped on test carrier 10 but do not affect the illumination of sending from light-emitting component 105, do not affect that the light that derives from carrier 10 passes this sheet or film 120 is received by photoelectric detector 103 yet.Also comprise alignment windows 33 on housing 30, this window 33 is used for aiming at a certain correspondence position on equipment, to guarantee whether to arrive in the housing interventional instrument the correct position of appointment.。Also be designed with adding mouth 31 on housing 30, this adding mouth 31 communicates with test carrier 10, when needs detect, sample is added from here and arrive on test carrier 10.Adding mouth its profile under the requirement of the function that satisfies application of sample is not limit, and in a specific embodiment, better coordinates with equipment 400 in order to make this housing 30, and this adding mouth 31 is designed to circular protrusions, and namely the outside is cylindrical, and inside is the structure of former taper.In addition, the person's hand that can also be designed with the handled easily on housing 30 is taken is affectedly bashful position 73, when the operator pinches this and is affectedly bashful position 73, can accurately insert or extract with equipment.For the operator can be accurately will be detected in the housing interventional instrument with test carrier, be designed with at the end away from sample tap 31 of housing 30 arrow 74 that the indication operator plugs direction, such as " ", " " or " → " etc.
In a specific embodiment, another part 203 of the element that is in the light is positioned on housing 30 and is corresponding with the window 90 that exposes test carrier, for example is positioned on the window on top shell component 71.The part 203 of element of being in the light can mark off different parts to window 90 by the different designs at window, for example by two tiny glazing bars 38,39 windows are divided into three wickets 35,36,37, such division just also just is divided into Three regions to the zone that is exposed by window 90 on test carrier, is for example test zone 130, reference zone 140 and test control area 150 are as shown in Figure 4 and 5 and 13.The element 203 that is in the light on the D of unit can be positioned on housing 30, and the element 203 that is in the light on this housing 30 is fixed the subregion on test carrier 10 and surround.Specifically, be positioned at the 61 and 62 common elements 203 that are in the light that consist of on housings 30 of the outer side shield of septulum bar 38,39 on window and window.After housing 30 interventional instruments 400 with test carrier 10, the element 203 that is in the light of this part coordinates with the element 202 that is in the light on equipment, form the space of a sealing, make the subregion on test carrier 10, light-emitting component 105 and photodetector 103 are positioned at this enclosure space.
In another specific embodiment, the element 202 that is in the light is positioned on equipment 400 with another separate part C that light-emitting component 105 and photodetector 103 consist of, as shown in Figure 4, this is positioned at the part 40(202 of the element that is in the light on equipment) as a whole, a projection 70 on being in the light componentry, this is arranged, on projection 70, a plurality of separated spaces are arranged, be used for installing light emitting element 105 and photodetector 103, and light-emitting component 105 and photodetector 103 are separated.In embodiment, as shown in Figure 10 and Figure 11, projection 701,702,703 and 704 is separated out the space of laying light-emitting component 105, is used for laying 3 light-emitting components, i.e. LED lamp 51,52 and 53 more specifically.The projection 705,706,707,708 and 709 that is positioned at the both sides of LED lamp is separated out 3 spaces of laying photodetector, and wherein, a side has a PD detecting device 42, and opposite side is laid two PD detecting devices 41,43.
In use, in order to guarantee to be fixed after housing 30 inserts fetch equipment 400, and make LED lamp and PD detecting device can with the corresponding regional fine registration of test carrier in housing 30, be designed with card article 406 and 407 on the element 40 that is in the light on equipment, this card article 406,407 lay respectively at the both sides of element 40 of being in the light, and have elasticity; Simultaneously, also be designed with at the back side of the element 40 that is in the light rectangular protruding 404, as shown in Figure 6; Corresponding with it, as shown in Figure 5, be designed with the side groove 32 that can hold card article 406,407 ports on the element that is in the light on housing 30, this groove 32 lays respectively at two sides of housing 30; And, also be designed with the rectangular recess 34 supporting with the back side projection 404 of the element 40 that is in the light on the upper part 71 of housing.When in housing 30 interventional instruments 400, card article 406 on element 40 is in the light, 407 sides along housing 30 slide, final card article 406,407 port falls into respectively in groove corresponding to housing side 32, fixing also locking housing 30, simultaneously, on housing, rectangular recess 34 is slided along the back projection 404 of the element that is in the light, slide into the fixed position of appointment when housing 30 after, the end of groove 34 also arrives the end of projection 404, both closely cooperates, thus the precision when guaranteeing housing and coordinative composition of equipments use.
Preferably, also have circular arc recess 48 on the element 40 that is in the light, when in housing 30 interventional instruments 400 and after arriving assigned address, this recess 48 circular adding mouth 31 on housing of conflicting, thus further be fixed in test carrier 10 and housing 30 in equipment.The equipment 400 of the element that is in the light and closely cooperating of housing 30 have also been guaranteed to comprise.In another preferred mode, insert in fetch equipment in order to ensure housing and arrive preposition, include the alignment windows corresponding with housing alignment windows 33 47 on the element 40 that is in the light.In a specific embodiment, can also set alignment windows 33 on housing with after alignment windows 47 on equipment is aimed at, this fetch equipment detects beginning.
Fig. 6 is the schematic rear view of element of being in the light on equipment, can find out in the figure, with window 35,36,37 correspondences on housing, the element 40 that is in the light on equipment also have 3 with window to deserved window 401,402,403.After housing 30 was inserted in equipment 400, two-part window is corresponding to be overlapped, and forms passage one by one.The light that these passages can make light-emitting component send shines on the zone of test carrier, and the light on this zone is turned back on photodetector.
In fetch equipment in preferred embodiment, as shown in Figure 4, at least one light-emitting component 105 comprises three light-emitting components, and each light-emitting component shines respectively the specific region of test carrier; At least one photodetector 103 comprises three photodetectors, for detection of the light of specific region on test carrier.Concrete, the first light-emitting component shines the test section; The second light-emitting component irradiation reference region; And the 3rd light-emitting component shines the control zone.And the first detecting device is corresponding to the first light-emitting component, and namely the first detecting device detects light that the first light-emitting component sends to the light of test zone back reflection; The second detecting device is corresponding to the second light-emitting component, and namely the second detecting device detects light that the second light-emitting component sends to the light of reference region back reflection; The 3rd detecting device detects the 3rd light that sends to the light of control zone back reflection.Like this, light-emitting component and photodetector detect one to one, can react more accurately the optical information of regional, guarantee the accuracy that detects.In specific embodiment, as shown in Figure 4, the corresponding photodetector 43 of LED lamp 51, it is the test zone 130 that the light that sends of LED lamp 51 arrives test carrier (test-strips) 10, then, on test zone 130, the light of reflection is detected by PD detecting device 43, at this moment, the light that LED lamp 51 sends only shines specific zone-test zone on test carrier, and 43 of PD detecting devices detect the light that zone-test zone fixing on test carrier sends.More specifically in embodiment, the LED lamp that is positioned on the element that is in the light is corresponding with a certain zone on test carrier, as shown in Fig. 7 and 8, LED lamp 53 is positioned on window 403 and shell window 37, corresponding to the control area 150 of test carrier, the illumination that this LED lamp 53 sends is mapped on corresponding control area; Light source led lamp 52 is positioned on window 402 and shell window 36, and corresponding to the reference zone 140 of test carrier, the light that LED lamp 52 sends shines directly on this reference zone 140; Light source led lamp 51 is positioned on window 401 and shell window 35, and corresponding to the test zone 130 of test carrier, the illumination of sending is mapped on test zone.Same, photodetector is also with it relation one to one, specifically as shown in figure 13, PD detecting device 41 is corresponding with control area 150, for detection of the light that sends from this control area, and PD detecting device 42 is corresponding with reference regional 140, detects the light that sends on this zone, PD detecting device 43 is corresponding with test zone 130, detects the light from this zone 130.
In a specific embodiment, this equipment also comprises the conducting light paths structure, and this path channels structure equally as shown in Figures 2 and 3.Conducting light paths structure 200,201 Main Function: the one, allow light-emitting component 105 can be to greatest extent illumination be mapped on test carrier 10 upper (the test zone for example in specific zone, one or several in reference zone or test control area), do not shine on other nonspecific zone; The conducting light paths structure also allows photoelectric detector 103 receive to greatest extent light from the specific region on test carrier 10 (test zone for example in addition, one or several in reference zone or test control area), rather than from the light on other unspecific zones.For example by the structure of design conducting light paths, only allow one or several light-emitting component only shine specific test zone and do not shine the control area; Only allow simultaneously light from test zone or test control area be detected by one of them photoelectric detector and do not detect the light of other test zone, for example reference zone.As shown in Figure 2, be in the light on equipment element 202 encloses be in the light element 203 and test carrier 10 and pcb board 102 on test carrier and forms conducting light paths structure 200.More specifically in embodiment, as shown in figure 12, the element 38,39 that is in the light on be in the light element 40 and housing on equipment, 61,62 are combined to form 3 path channels structures 80; Be also window 401 combinations on element of being in the light on window 35 and equipment on housing, and lay LED lamp 51 and coordinate with the space that separates of PD detecting device 43, form a conducting light paths structure 80.Shown in Figure 12, the conducting light paths structure 80 of surrounding test zone 130 is by the element 75 that is in the light of the part on housing 30,76 and equipment on the element projection 408,409 that is in the light combine, form a complete conducting light paths structure in conjunction with test zone 130 and the pcb board 102 of test carrier 10.This structure can make light a that LED lamp 51 sends only shine the zone of window 35 on housing, it is the test zone 130 of test carrier, and after test zone 130 or the film on it 120 receive this light a, reflect, the light b that reflects is received by PD detecting device 43, completes the detection by optics on test zone 130; Same, be in the light on window 36 and equipment on housing window 402 combinations of element, coordinate with the space of laying LED lamp 52 and PD detecting device 42, form another conducting light paths structure, in this another conducting light paths structure, the illumination that LED lamp 52 sends is mapped to the reference zone 140 of test carrier, and then the reference zone is reflected, light after reflection is detected by PD detecting device 42, completes the detection by optics on reference zone 140; Be in the light on window 37 and equipment on housing window 403 combinations of element, coordinate with the space of laying LED lamp 53 and PD detecting device 41, form the 3rd conducting light paths structure, in this structure, the light that LED lamp 53 sends only shines on the control area 150 of test carrier, again by the control area with this light reflection, the light of reflection only can be received by PD detecting device 41, completes the detection by optics on control area 150.
Fig. 3 is a preferred structural representation of the present invention's represented embodiment in Fig. 2.Concrete conducting light paths project organization is arranged in Fig. 2 and Fig. 3, in order to reduce domatic 106 pairs of light-emitting components 105 of 110 parts in Fig. 2, or the LED lamp 51 reflection of light effect of sending and the interference that causes, being configured to one to domatic 106 is positioned at equipment domatic 2021 on the element that be in the light and is positioned at face vertical on housing 2031 with one, this vertical plane 2031 is vertical with the face at test carrier 10 places, as Fig. 3 and shown in Figure 12.In such structure, because of the existence of vertical plane, make the area change that receives the light that LED lamp 51 sends on test zone; And the light c that LED lamp 51 sends is reflected after arriving vertical plane 2031, and the light d of reflection can arrive on test zone 130, as shown in figure 14, has increased the amount of incident ray on test zone 130, makes the detection better effects if.
Simultaneously, as Fig. 3 and shown in Figure 12, directly reflex in photodetector be mapped on the sidewall of the element 101 that is in the light in order to reduce illumination that light-emitting component 105 sends after, original structure on a vertical plane is changed near the zone of test carrier part cave in backward, form a groove area 85, namely two parts of the conducting light paths structure of contiguous light-emitting component are on same vertical plane, the face 2032 on housing of being positioned at than the face 2022 on equipment of being positioned at away from light-emitting component 105.Like this, the light that light-emitting component sends all shines the specific region on test carrier because having lacked stopping of sidewall, thereby, the more effective light source that utilizes.Namely after light-emitting component 105 or LED lamp 51 emit beam, have the part light emission to each face of this conducting light paths structure, and reflect, the face of contiguous light-emitting component 105 or LED lamp 51 also can receive light and reflect, and the light great majority of reflection can shine directly on photodetector 103, can affect testing result; And the face 2032 on housing is after light-emitting component 105, form a groove 85 between the face 2022 of the element that is in the light on test carrier 10 and equipment, after light e that light-emitting component 105 or LED lamp 51 send arrives groove 85, can be through groove 85 sidewall reflects, reflection ray f arrives on the test zone 130 of test carrier 10, as shown in figure 15, like this, both reduce the light that does not shine on test carrier 10 and directly reflexed to photodetector 103, or on PD detecting device 43, increase again simultaneously on the test zone 130 that light incides test carrier 10.
In another preferred implementation, as shown in Figures 2 and 3, also there are another parts 104 that are in the light between light-emitting component and photodetector.This another parts 104 that are in the light can separate light-emitting component and photodetector, thereby avoid shining directly on photodetector on light-emitting component, the testing result of stray light detecting device.In specific embodiment, as Fig. 4 and shown in Figure 12, another parts that are in the light 44 and 45 are distributed on the both sides of LED lamp, separate all LED lamps and PD detecting device.This another parts 44,45 that are in the light are a rectangular lighttight partition, and preferred, this partition is identical with the element material that is in the light.
Below just the concrete use operation of the fetch equipment 300 shown in Fig. 4 of the present invention-13 be specifically described.when detecting, be split with the housing 30 of test carrier 10 and fetch equipment 400, the sample that needs detection in the adding mouth 31 places interpolation of housing 30, housing 30 is kept flat and a standing end after the time, as 5 minutes, that holds housing is affectedly bashful position 73, according to housing upward arrow 74 direction indications, housing 30 is inserted in fetch equipment 400, after in the complete interventional instrument 400 of housing 30, be after on the alignment windows 33 of housing and equipment, alignment windows 47 is aimed at, this fetch equipment 300 starts, at first the LED lamp 51, 52, 53 is luminous successively, shine successively the zone of its correspondence: test zone 130, reference zone 140, control area 150, then, reflection ray on regional enters respectively its special PD detecting device 43, 42, 41, complete corresponding detection.
In addition, according to reality, fetch equipment disclosed in this invention can also comprise optical access system, and this system has detailed description at application number 200910126658.3 or 200410063910.0 in the Chinese patent application in June 4 2004 applying date.In these disclosed documents, each concrete embodiment can consist of technical approach of the present invention with scheme combination disclosed by the invention, and becomes a part of the present invention.
Claims (29)
1. the equipment of chemical examination test result on a read test carrier comprises:
Test carrier; At least one light-emitting component sends light and shines on test carrier in corresponding one or more districts;
At least one photodetector is for detection of the light that sends the one or more districts from described test carrier;
With the element that is in the light, the element that is in the light can stop that extraneous light enters in this equipment.
2. equipment according to claim 1, is characterized in that, test carrier coordinates with this equipment with the form that can unload.
3. equipment according to claim 2, is characterized in that, the element that is in the light is comprised of two parts at least, this at least two parts be in the light and coordinate with the form that can unload between element.
4. equipment according to claim 3, is characterized in that, wherein, the element that is in the light of the part in two parts is positioned on equipment at least, and the element that is in the light of the another part in two parts is positioned on test carrier at least.
5. equipment according to claim 4, is characterized in that, wherein said another part element that is in the light is positioned on the test zone of test carrier.
6. equipment according to claim 4, is characterized in that, wherein said another part element that is in the light also is positioned at the detection control area of test carrier or/and on the reference zone.
7. equipment according to claim 4, is characterized in that, test carrier is arranged in a housing, and the element that is in the light of the another part in described two parts at least is positioned on this housing.
8. equipment according to claim 7, is characterized in that, described housing comprises the window corresponding with the test carrier subregion, and the element that is in the light of the another part in described two parts at least is positioned on this window.
9. equipment according to claim 8, is characterized in that, the element that is in the light of the another part in described two parts at least is divided at least two parts to window.
10. equipment claimed in claim 9, is characterized in that, the element that is in the light of the another part in described two parts at least is divided into window test zone and detects the control area.
11. according to equipment claimed in claim 9, it is characterized in that, the element that is in the light of the another part in described two parts at least is divided into window test zone, reference zone and detects the control area.
12. according to claim 5 or 6 described equipment, it is characterized in that, a described part that is positioned on equipment element and another part on being positioned at test carrier element that is in the light that is in the light coordinates to form and can stop that external light source enters test zone and/or reference zone on test carrier and/or detects the structure of control area.
13. equipment according to claim 8, it is characterized in that, when the housing that test carrier is arranged is inserted in this equipment, is positioned at a part on equipment element and another part on being positioned at housing element that is in the light that is in the light and coordinates to form and to stop that extraneous veiling glare enters the structure of window.
14. one of according to claim 1-4 described equipment, it is characterized in that, the described part element that is in the light forms the conducting light paths structure, the light that light-emitting component sends can be shone on test carrier for this conducting light paths structure, allows simultaneously the light that sends in one or more districts on test carrier be received by photodetector.
15. equipment according to claim 14 is characterized in that, this conducting light paths structure is divided into two parts, coordinates with the form that can unload between two parts.
16. equipment according to claim 15 is characterized in that, the part of conducting light paths structure is positioned on equipment, and another part of conducting light paths structure is positioned on test carrier.
17. equipment according to claim 16 is characterized in that, test carrier is arranged in a housing, and this housing comprises the window corresponding with the test carrier subregion, and another part of described conducting light paths structure is positioned on the window of this housing.
18. according to claim 1 or 17 described equipment is characterized in that, described at least one light-emitting component comprises three light-emitting components, and described at least one photodetector comprises three photodetectors.
19. equipment according to claim 18 is characterized in that, the described element that is in the light forms three conducting light paths structures.
20. equipment according to claim 19, it is characterized in that, described three light-emitting components, three photodetectors and three conducting light paths elements are one-to-one relationship, i.e. light-emitting component, photodetector and conducting light paths structure form a conducting light paths system.
21. equipment according to claim 20 is characterized in that, each conducting light paths system is corresponding to the test zone of test carrier, or the reference zone, or the control area.
22. equipment according to claim 21 is characterized in that, the test zone of the corresponding test carrier of the first light-emitting component, and corresponding with the first photodetector, be positioned at the first conducting light paths structure.
23. equipment according to claim 21 is characterized in that, the reference zone of the corresponding test carrier of the second light-emitting component, and corresponding with the second photodetector, be positioned at the second conducting light paths structure.
24. equipment according to claim 21 is characterized in that, the control area of the corresponding test carrier of the 3rd light-emitting component, and corresponding with the 3rd photodetector, be positioned at the 3rd conducting light paths structure.
25. one of according to claim 20-24 described equipment is characterized in that a described light-emitting component and the corresponding sensitivity that improves detection of photodetector.
26. equipment according to claim 25 is characterized in that, described three photodetectors are respectively in the both sides of light-emitting component.
27. equipment according to claim 26 is characterized in that, comprises one to one another parts that are in the light between light-emitting component and photodetector, this another be in the light parts will be one to one light-emitting component and photodetector separation.
28. equipment according to claim 27 is characterized in that, in each conducting light paths system, the face that is positioned at the conducting light paths structure adjacent light detecting device on equipment is domatic; The face that is positioned at the conducting light paths structure adjacent light detecting device on housing is vertical plane.
29. according to claim 26 or 28 described equipment, it is characterized in that, in each conducting light paths system, two parts of the conducting light paths structure of described contiguous light-emitting component are positioned at part on housing than being positioned at part on equipment away from light-emitting component not on same vertical plane.
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| CN201110366446.2A CN103115899B (en) | 2011-11-17 | 2011-11-17 | The equipment of result of laboratory test on a kind of read test carrier |
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| CN201110366446.2A CN103115899B (en) | 2011-11-17 | 2011-11-17 | The equipment of result of laboratory test on a kind of read test carrier |
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| CN103115899A true CN103115899A (en) | 2013-05-22 |
| CN103115899B CN103115899B (en) | 2018-01-16 |
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Cited By (1)
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| CN110057819A (en) * | 2019-04-04 | 2019-07-26 | 浙江东方基因生物制品股份有限公司 | A kind of electronic reading out device |
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| CN103115899B (en) | 2018-01-16 |
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