CN110025719A - A kind of Chinese medicinal formulae and preparation method thereof for treating lung cancer - Google Patents

A kind of Chinese medicinal formulae and preparation method thereof for treating lung cancer Download PDF

Info

Publication number
CN110025719A
CN110025719A CN201910343636.9A CN201910343636A CN110025719A CN 110025719 A CN110025719 A CN 110025719A CN 201910343636 A CN201910343636 A CN 201910343636A CN 110025719 A CN110025719 A CN 110025719A
Authority
CN
China
Prior art keywords
parts
lung cancer
chinese medicinal
medicinal formulae
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910343636.9A
Other languages
Chinese (zh)
Inventor
陈凯芸
陈志道
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Jianheng Institute Of Traditional Chinese Medicine
Original Assignee
Hangzhou Jianheng Institute Of Traditional Chinese Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hangzhou Jianheng Institute Of Traditional Chinese Medicine filed Critical Hangzhou Jianheng Institute Of Traditional Chinese Medicine
Priority to CN201910343636.9A priority Critical patent/CN110025719A/en
Publication of CN110025719A publication Critical patent/CN110025719A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965Asparagus, e.g. garden asparagus or asparagus fern
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of Chinese medicinal formulaes and preparation method thereof for treating lung cancer, drug price in order to solve the problems, such as to treat lung cancer in the prior art is high, therapeutic effect is poor, proposes a kind of technical solution are as follows: a kind of Chinese medicinal formulae for treating lung cancer includes following component according to parts by weight: double 28-32 parts of grass of dragon, open country 28-32 parts of Radix Angelicae Sinensis, 18-22 parts of Radix Rehmanniae, 10-14 parts of asparagus fern, 18-22 parts of cordate houttuynia, 10-14 parts of the root bark of tree peony, 10-14 parts of alkanet;Preparation method includes the following steps: S1: weighing the medicinal material of specified amount and successively puts into medicinal material in casserole;S2: clear water is added in casserole and decocts 1 hour;Filter residue and filtrate are collected in filtering;S3: clear water is added into filter residue again and decocts 1 hour;Filtrate is collected in filtering;S4: merge the filtrate being obtained by filtration twice, obtain Chinese medicinal formulae.Present component is simple, cheap and curative effect is preferable.

Description

A kind of Chinese medicinal formulae and preparation method thereof for treating lung cancer
Technical field
The present invention relates to a kind of Chinese medicinal formulaes and preparation method thereof, and in particular to treats Chinese medicinal formulae and its preparation of lung cancer Method.
Background technique
According to the statistics of the World Health Organization, the annual pathogenesis of cancer number about 10,000,000 in the whole world, dead about 7,000,000 people, oneself at For the second killer of the mankind for being only second to cardiovascular disease.The death rate of lung cancer is first of cancer, and clinically lung cancer can be divided into cellule Lung cancer (SCLC) and non-small cell type lung cancer (NSCLC), wherein NSCLC includes gland cancer, squamous carcinoma and maxicell lung cancer, accounts for about lung cancer The 80-85% of sum, due to lacking early diagnosis and effective treatment means, 5 years survival rates of NSCLC are less than 15%.Although putting Chemotherapy is widely used in NSCLC, and since long-term survival rate is low, toxic side effect is big, and curative effect is simultaneously unsatisfactory.
At present in the chemotherapeutics of the most direct kill tumour cell of clinical application, since its cytotoxicity and multiple medicine are resistance to Pharmacological property makes its development encounter bottleneck, and nearly stage difficulty has breakthrough.Treatment of Lung Cancer with Chinese Medicine clinical experience proves that lung cancer is postoperative to match Chinese medicine treatment is closed, postoperative rehabilitation can be accelerated, improves operative effect, delays even to contain useless cancer recurrence and transfer, for extending Patient survival improves its quality of life and has preferable effect.The drug variety of Current therapeutic lung cancer is various, however cure rate The shortcomings that not high, and that there is drug prices is higher, and patient wants Long-term taking medicine.
If publication date is on July 21st, 2004, the Chinese patent of Publication No. CN1158091C, which proposes, a kind of treats lung The Chinese medicine composition of cancer, costly, and the Chinese medicine composition needs the drug prices such as cordyceps sinensis used, the root of straight ladybell in the invention It takes for a long time just effective.
Summary of the invention
It is an object of the invention to overcome the above deficiencies in the existing technologies, and provide it is a kind of simple, conveniently, treatment The Chinese medicinal formulae for the treatment of lung cancer and preparation method thereof that effect is good, medicine valence is low.
Technical solution used by the present invention solves the above problems is: the Chinese medicinal formulae of the treatment lung cancer includes by weight The following component of number meter: double 28-32 parts of grass of dragon, wild 28-32 parts of Radix Angelicae Sinensis, 18-22 parts of Radix Rehmanniae, 10-14 parts of asparagus fern, cordate houttuynia 18- 22 parts, 10-14 parts of the root bark of tree peony, 10-14 parts of alkanet.
Preferably, the Chinese medicinal formulae of heretofore described treatment lung cancer includes following component according to parts by weight: double Imperial 30 parts of grass, wild 30 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae, 12 parts of asparagus fern, 20 parts of cordate houttuynia, 12 parts of the root bark of tree peony, 12 parts of alkanet.
A kind of preparation method of Chinese medicinal formulae that treating lung cancer includes the following steps:
S1: double dragon grass, the wild Radix Angelicae Sinensis, Radix Rehmanniae, asparagus fern, cordate houttuynia, the root bark of tree peony, alkanet of specified amount are weighed, and medicinal material is successively thrown Enter into casserole;
S2: being added clear water in casserole and decoct 1 hour, and the weight of clear water is 10 times of medicinal material total weight;Filtering, collect filter residue and Filtrate;
S3: clear water being added into filter residue again and decocts 1 hour, and the weight of clear water is 8 times of medicinal material total weight;Filtrate is collected in filtering;
S4: merge the filtrate being obtained by filtration twice, obtain Chinese medicinal formulae.
Preferably, the Chinese medicinal formulae of heretofore described treatment lung cancer avoids eating seafood and cattle and sheep in duration of medication patient Meat.
Preferably, the dosage of the Chinese medicinal formulae of heretofore described treatment lung cancer be it is adult twice daily, each 100- 125ml。
The pharmacological action for the various bulk pharmaceutical chemicals that the present invention uses is as follows:
Double dragon grass: mainly having dispelling wind removing toxic substances, clearing away heat to and alleviating pain and other effects, can be used to treat venomous snake bite, abscess of throat and each Kind tumour.
Wild Radix Angelicae Sinensis: bitter in taste, pungent, cold nature;Channel tropism, lung, spleen, Liver Channel;Function blood-nourishing effect, menstruation regulating, promoting blood circulation and stopping pain, ease constipation are logical Just, irregular menstruation, dysmenorrhea, hemostasis amenorrhoea, anaemia, rheumatic arthralgia, traumatic injury, dry constipation of intestines are cured mainly.
Radix rehmanniae recen: it is cold in nature sweet in flavor, have the function of clearing heat and cooling blood, nourishing Yin and promoting production of body fluid;It can be used to treat various hot illnesss, enter The diseases such as febrile virulent maculae, blood-head bleeding, consumption of YIN caused by febrile disease, fever due to yin deficiency and Tianjin hinder constipation;Enhance immune function: radix rehmanniae recen can be bright The immune function of aobvious raising body, can enhance the generation of bone-marrow-derived lymphocyte antibody, increase the content of hemolysin in serum, stimulate T Lymphocyte transformation enhances delayed allergy, promotes the function of cellular immunity at sensitized lymphocyte;Antitumor action: The antitumor action of radix rehmanniae recen enhances that body's immunity is closely related with it, contained polysaccharide be its it is antitumor it is effective at / mono-, it can significantly inhibit tumour growth.
Asparagus fern: energy nourishing Yin and promoting production of body fluid, moistening lung and clearing away the heart-fire are used for dryness of the lung dry cough, cough due to consumptive disease, injury thirst, vexed insomnia, interior heat It quenches one's thirst, the symptoms such as dry constipation of intestines, diphtheria;Antitumor: the root tuber of asparagus fern has antitumor efficacy, and asparagus fern is for acute lymphoblastic The leucocyte dehydrogenase of type leukaemia, chronic myelocytic leukemia and Acute monocytic type leukaemic has certain suppression Production is used, and it is able to suppress the breathing of acute lymphoblastic type leukaemic's leucocyte;Antibacterial: asparagus fern root tuber also has Fabulous antibacterial curative effect;Asparagus fern root tuber decoction is in vitro to bacillus anthracis, A type and beta hemolytic streptococcus, corynebacterium diphtheriae, class Corynebacterium diphtheriae, Diplococcus pneumopniae, staphylococcus aureus, Staphylococcus citreus, staphylococcus albus and hay bacillus etc. are each Class fungi has different degrees of inhibiting effect;Delay senescence: asparagus fern root tuber has fabulous anti-oxidant and anti-aging to human body It acts on, containing the effective component to delay senescence in the extract of asparagus fern, asparagus fern polysaccharide, which has, removes free radical and anti peroxidation of lipid Active effect.
Cordate houttuynia: have antibacterial, anticancer, it is antiviral the effect of, control enteritis, dysentery, nephritic dropsy and mazoitis, tympanitis Deng;The carbuncle that disappears apocenosis: cordate houttuynia is pungent cold, the carbuncle that can disappear apocenosis, can external curing pathopyretic ulcer and treatment phlegm heat heap soil or fertilizer over and around the roots Lung, pectoralgia, the illnesss such as cough vomiting of pus and blood is stench;Enhancing is immune: the phagocytic activity of leucocyte can be enhanced in cordate houttuynia, and it is standby to improve serum Xie Su, when treating tracheitis, sodium houttuyfonate can make patient's leucocyte obviously mention the staphylococcic phagocytic activity of white Height, serum properdin are significantly raised.
Cortex moutan: clearing heat and cooling blood: cortex moutan acrid flavour, cold nature have the function of clearing heat and cooling blood, are usually used in treatment heat and join the army Blood, fever due to yin deficiency, hematemesis and epistaxis, carbuncle sore tumefacting virus etc.;Anti-inflammatory analgesic: cortex moutan is commonly used to joint caused by treatment a variety of causes Inflammation can inhibit inflammation, swelling, exudation, inhibit capillary permeability;Although its analgesic activity is not strong, in compound, can add The effect of strong main ingredient;Tranquilizing to relieve muscle spasm: paeonol can substantially reduce spontaneous activity in mice, there is significant calm effect;Paeonol pair Caused by acetylcholine, isolated ileum segments in guinea pigs strong contraction has significant spasmolysis;Contained Paeoniflorin is to intestinal smooth With significant spasmolysis;Improve immunity: to rat oral gavage cortex moutan extracting solution, microscopically observation, it is seen that withered in liver In Schwann Cells and spleen macrophage phagocytic activity enhance, from this point as can be seen that cortex moutan can enhance immunity of organisms, help to Anti-bacterium invasion.
Asian puccoon: have effects that promoting blood circulation and cooling blood, removing toxic substances promoting eruption, can be used for treating the diseases such as macula, sore, eczema, scald;Solution Malicious nti-freckle: Asian puccoon is salty-cold, enters Liver Channel blood system, can cooling and activating blood and promoting eruption of detoxifying, can be used to treat febrile virulent maculae, void Very, there are the illnesss such as purple blackspot rash to heat toxin in skin;Antitumor: alkanet has chorioepithelioma and chorioadenoma certain Curative effect;With methylene blue test tube method primary dcreening operation, alkanet has extremely slight inhibiting effect to acute lymphoblastic leukemia;Asian puccoon can be reduced The disease incidence of spontaneous mammary carcinoma.
Compared with prior art, the present invention having the following advantages that and effect: the Chinese medicinal formulae in the present invention is only by 7 taste medium-height grass Medicine composition, related Chinese herbal medicine is common Chinese medicine, and cheap, convenient for various regions, patient is taken.And the Chinese medicinal formulae pair Patient has apparent curative effect, and 200 patients with lung cancer discovery of the traditional Chinese herbal decoction: 5 years survival rates of patient is taken through investigating 76%;And there is 87.6% patient symptom to be improved.
Specific embodiment
Below by embodiment, the present invention is described in further detail, following embodiment be explanation of the invention and The invention is not limited to following embodiments.
Embodiment 1.
The Chinese medicinal formulae for the treatment of lung cancer includes following component according to parts by weight in the present embodiment: double 30 parts of dragon grass, open country 30 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae, 12 parts of asparagus fern, 20 parts of cordate houttuynia, 12 parts of the root bark of tree peony, 12 parts of alkanet.
The preparation method that the Chinese medicinal formulae of lung cancer is treated in the present embodiment includes the following steps:
S1: double dragon grass, wild Radix Angelicae Sinensis, Radix Rehmanniae, asparagus fern, cordate houttuynia, the root bark of tree peony, the alkanet for weighing specified amount are put into casserole;
S2: being added clear water in casserole and decoct 1 hour, and the weight of clear water is 10 times of Chinese herbal medicine total weight;Filter residue is collected in filtering And filtrate;
S3: clear water being added into filter residue again and decocts 1 hour, and the weight of clear water is 8 times of Chinese herbal medicine total weight;Filter is collected in filtering Liquid;
S4: merge the filtrate being obtained by filtration twice, obtain Chinese medicinal formulae.
The dosage of the Chinese medicinal formulae of the treatment lung cancer be it is adult twice daily, each 100-125ml;The Chinese medicine for treating lung cancer Prescription avoids eating seafood and beef and mutton in duration of medication patient.
Embodiment 2.
The present embodiment and the difference of embodiment 1 are as follows:
The Chinese medicinal formulae for the treatment of lung cancer includes following component according to parts by weight in the present embodiment: double 28 parts of dragon grass, wild Radix Angelicae Sinensis 28 parts, 18 parts of Radix Rehmanniae, 10 parts of asparagus fern, 18 parts of cordate houttuynia, 10 parts of the root bark of tree peony, 10 parts of alkanet.
Embodiment 3.
The present embodiment and the difference of embodiment 1 are as follows:
The Chinese medicinal formulae for the treatment of lung cancer includes following component according to parts by weight in the present embodiment: double 32 parts of dragon grass, wild Radix Angelicae Sinensis 32 parts, 22 parts of Radix Rehmanniae, 14 parts of asparagus fern, 22 parts of cordate houttuynia, 14 parts of the root bark of tree peony, 14 parts of alkanet.
Embodiment 4.
The present embodiment and the difference of embodiment 1 are as follows:
The Chinese medicinal formulae for the treatment of lung cancer includes following component according to parts by weight in the present embodiment: double 29 parts of dragon grass, wild Radix Angelicae Sinensis 29 parts, 19 parts of Radix Rehmanniae, 11 parts of asparagus fern, 19 parts of cordate houttuynia, 11 parts of the root bark of tree peony, 11 parts of alkanet.
Embodiment 5.
The present embodiment and the difference of embodiment 1 are as follows:
The Chinese medicinal formulae for the treatment of lung cancer includes following component according to parts by weight in the present embodiment: double 31 parts of dragon grass, wild Radix Angelicae Sinensis 31 parts, 21 parts of Radix Rehmanniae, 13 parts of asparagus fern, 21 parts of cordate houttuynia, 13 parts of the root bark of tree peony, 13 parts of alkanet.
Clinical case.
Further to investigate curative effect of medication of the present invention, clinical experimental study, all patients are carried out to the patient with lung cancer Voluntarily receive treatment, reflection is good, no obvious toxic-side effects.The following are the typical cases of clinical test.
Patient 1: Liu, female, and 64 years old.
First visit result: CT examination shows right lung Ca with mediastinal lymph node metastasis, hydropericardium, a large amount of pleural effusions;Liver function Show: SGPT is increased, and patient had shortness of breath, cyanotic lips at that time, and jugular vein, which is exerted, to be opened, and considers lung Ca advanced stage, and pericardium, pleural effusion influence Lung function gives hydrothorax drainage, protect liver, the treatment such as nutrition;Patient is out of breath after treatment is clearly better, and liver function is restored substantially, gives strong Ten Cisplatin chemotherapy are selected, in conjunction with Chinese traditional treatment;Two examine after taking traditional Chinese herbal decoction 7 days in embodiment 1.
Two examine result: patient's cough is out of breath to be clearly better, and no blood-stained sputum, tongue is red, and whitish tongue is greasy, and arteries and veins slightly counts, and checks B ultrasound Show a small amount of hydropericardium, pleural effusion has significantly reduced, and sb.'s illness took a favorable turn;It is taken three behind traditional Chinese herbal decoction 7 days in embodiment 1 again It examines.
Three examine result: all diseases of patient are substantially reduced, no hemoptysis;Check CT shows that pulmonary lesions have been obviously reduced, pericardium, chest Chamber disappears substantially.
Patient 2: Shen, male, and 67 years old.
First visit result: there is blood urine in patient's five years ago, upon examination it is found that bladder cancer, gives bladder ca radical correction, it is postoperative to give bladder Perfusion chemotherapy, stable disease, no relapse and transfer;Appearance fever, cough, phlegm are few before one week, do not treat;CT examination discovery is right Lower lung lobar pneumonia;Blood routine shows leucocyte 15600/mm3, neutrophil leucocyte 82%;Take the Chinese medicinal decoction in embodiment 1 Two examine after agent 7 days.
Two examine result: patient's resolution of fever, and cough improves, bottom right lung can and a small amount of bubble, red tongue with thin and yellowish fur, arteries and veins omit Number, then take behind traditional Chinese herbal decoction 7 days in embodiment 1 three and examine.
Three examine result: patient shows that right lung lesion disappears substantially without obvious cough, fever check CT, clinical cure.
Patient 3: Tan, male, and 59 years old.
First visit result: patient's five years ago is because lung Ca row upper left pneumonectomy+hilar and mediastinal lymph node cleans, during postoperative pathological shows Break up gland cancer, it is postoperative to give 4 period of TP scheme chemotherapy;The left limb that happened suddenly before 2 days is out of strength, and headache, vomiting are checked through MRI and prompted Lung cancer metastasis, brain edema give Whole-brain radiotherapy, and Chinese medicine are combined to treat;Two examine after taking traditional Chinese herbal decoction 7 days in embodiment 1.
Two examine result: patient's headache, vomiting disappear, left limb improvement out of strength, consider radiotherapy and Li Shui easily to impairment of yin, therefore Former Fang Jiayong radix rehmanniae recen 30g, asparagus fern 12g;Three examine after taking again 15.
Three examine result: the left myodynamia of patient improves, and check MRI shows that brain tumor reduces, and brain edema subsides substantially.
Patient 4: Hu, male, and 72 years old.
First visit result: patient often feels left rib secret anguish over nearly 3 months, and unable to lie due to dyspnea checks diagnosis through iconography and laboratory For exudative pleurisy, etiology unknown;Multiple row pneumothorax paracentesis, Relapse rate are refractory;X-ray film and B ultrasound show, left side Thoracic cavity moderate hydrops;Two examine after taking traditional Chinese herbal decoction 7 days in embodiment 1.
Two examine result: the left rib secret anguish of patient disappears, and breathes with cough, shortness of breath is relieved, tongue drop, husky tongue fur, veins string, chest pa & lat The a small amount of hydrops of X-ray film and B ultrasound display left side thoracic cavity, pachynsis pleurae sample change.
Patient 5: Mr. Wang, male, and 55 years old.
First visit result: patient's two years ago is because cough finds thymoma, and the state of an illness is still stable after giving radiotherapy;Nothing was played before 15 days Obviously inducement gradually appears uncomfortable in chest out of breath, cannot lie down, and ultrasound diagnosis prompts large pericardial effusion, pleural effusion;Give hydropericardium Symptom mitigates after drainage, but hydropericardium still has 50 ~ 100ml daily, to reinforce treating and Chinese medicine of seeing a doctor;It takes in embodiment 1 Traditional Chinese herbal decoction 7 days after two examine.
Two examine result: patient's hydropericardium significantly reduces, and only drains 20ml or so daily, and hydrops switched to it is yellowish Color, it is uncomfortable in chest it is out of breath be clearly better, tongue vein as before, therefore original side in lepidium seed be kept to 15g, go rhizoma alismatis, the tuber of pinellia processed to take 7 doses again;It takes Three examine behind traditional Chinese herbal decoction 7 days in embodiment 1.
Three examine result: patient is without uncomfortable in chest, out of breath, drainage of pericardium without obvious hydrops, and check B ultrasound and show: pericardium has no long-pending Liquid pulls out drainage tube.
Patient 6: Yan, male, and 85 years old.
First visit result: 3 Nian Qianjing physical examination of patient finds pulmonary masses, considers that lung Ca, Bronchofiberscope routine pathology show on right lung The small thin chest cancer of leaf, at that time without cough and expectoration, no pectoralgia is uncomfortable in chest out of breath, and take traditional Chinese medicine always treatment;Occurred before 2 months out of breath and gradually Aggravate, look into CT show right lung central type lung Ca with mediastinum, right lung door Lymph Node Metastasis, middle lobe of right lung obstructive atelectasis, pleural effusion, Superior vena cava is pressurized;The treatment such as hydrothorax drainage, anti-inflammatory is given after being admitted to hospital;But still sense is uncomfortable in chest out of breath, and it is comprehensive to be thought of as superior vena cava compression Disease is closed, family members are reluctant row superior vena cava Stent, therefore add and treated with Chinese medicine;After taking traditional Chinese herbal decoction 7 days in embodiment 1 Two examine.
Two examine result: patient facial region's oedema, uncomfortable in chest out of breath to be improved.
In addition, it should be noted that, the specific embodiments described in this specification, the shape of parts and components are named Title etc. can be different, and above content is only to structure of the invention example explanation described in this specification.It is all according to According to equivalence changes or simple change that the invention patent design structure, feature and principle is done, it is included in this hair In the protection scope of bright patent.Those skilled in the art can do described specific embodiment various The mode that the modify or supplement or adopt of various kinds is similar substitutes, and without departing from structure of the invention or surmounts present claims Range defined in book, is within the scope of protection of the invention.

Claims (5)

1. a kind of Chinese medicinal formulae for treating lung cancer, which is characterized in that the Chinese medicinal formulae of the treatment lung cancer includes according to parts by weight Following component: it is double dragon 28-32 parts of grass, open country 28-32 parts of Radix Angelicae Sinensis, 18-22 parts of Radix Rehmanniae, 10-14 parts of asparagus fern, 18-22 parts of cordate houttuynia, 10-14 parts of the root bark of tree peony, 10-14 parts of alkanet.
2. the Chinese medicinal formulae for the treatment of lung cancer according to claim 1, which is characterized in that the Chinese medicinal formulae packet of the treatment lung cancer Include following component according to parts by weight: double 30 parts of dragon grass, wild 30 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae, 12 parts of asparagus fern, 20 parts of cordate houttuynia, 12 parts of the root bark of tree peony, 12 parts of alkanet.
3. a kind of preparation method of the Chinese medicinal formulae of the treatment lung cancer as described in claim 1-2 any claim, feature It is, includes the following steps:
S1: weighing double dragon grass, the wild Radix Angelicae Sinensis, Radix Rehmanniae, asparagus fern, cordate houttuynia, the root bark of tree peony, alkanet of specified amount, by weighed medicinal material according to In secondary investment casserole;
S2: being added clear water in casserole and decoct 1 hour, and the weight of clear water is 10 times of medicinal material total weight;Filtering, collect filter residue and Filtrate;
S3: clear water being added into filter residue again and decocts 1 hour, and the weight of clear water is 8 times of medicinal material total weight;Filtrate is collected in filtering;
S4: merge the filtrate being obtained by filtration twice, obtain Chinese medicinal formulae.
4. a kind of application method of the Chinese medicinal formulae of the treatment lung cancer as described in claim 1-2 any claim, feature Be, the dosage of the Chinese medicinal formulae of the treatment lung cancer be it is adult twice daily, each 100-125ml.
5. the application method of the Chinese medicinal formulae for the treatment of lung cancer according to claim 4, which is characterized in that suffer from duration of medication Person avoids eating seafood and beef and mutton.
CN201910343636.9A 2019-04-26 2019-04-26 A kind of Chinese medicinal formulae and preparation method thereof for treating lung cancer Pending CN110025719A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910343636.9A CN110025719A (en) 2019-04-26 2019-04-26 A kind of Chinese medicinal formulae and preparation method thereof for treating lung cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910343636.9A CN110025719A (en) 2019-04-26 2019-04-26 A kind of Chinese medicinal formulae and preparation method thereof for treating lung cancer

Publications (1)

Publication Number Publication Date
CN110025719A true CN110025719A (en) 2019-07-19

Family

ID=67240390

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910343636.9A Pending CN110025719A (en) 2019-04-26 2019-04-26 A kind of Chinese medicinal formulae and preparation method thereof for treating lung cancer

Country Status (1)

Country Link
CN (1) CN110025719A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1094957A (en) * 1993-06-07 1994-11-16 宫龙章 Xiaojianwan pill for eliminating hard masses
CN101524436A (en) * 2008-03-06 2009-09-09 北京中科仁和科技有限公司 Chinese medicinal composition for treating lung cancer
CN103055100A (en) * 2010-07-21 2013-04-24 李政育 Traditional Chinese medicine composition for inhibiting growth of cancer cells and traditional Chinese medicine extract thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1094957A (en) * 1993-06-07 1994-11-16 宫龙章 Xiaojianwan pill for eliminating hard masses
CN101524436A (en) * 2008-03-06 2009-09-09 北京中科仁和科技有限公司 Chinese medicinal composition for treating lung cancer
CN103055100A (en) * 2010-07-21 2013-04-24 李政育 Traditional Chinese medicine composition for inhibiting growth of cancer cells and traditional Chinese medicine extract thereof

Similar Documents

Publication Publication Date Title
CN102178804B (en) Chinese medicinal composition for treating perianal eczema and preparation method thereof
CN103520572B (en) A kind of Chinese medicine composition being used for the treatment of atopic dermatitis and preparation method thereof
CN103652360B (en) Feed for curing pig paratyphus and preparation method thereof
CN103933425A (en) Traditional Chinese medicine composition for treating lung cancer and preparation method thereof
CN104208245A (en) Traditional Chinese medicine medicated bath for tinea of feet and hands and preparation method thereof
CN102078569B (en) Traditional Chinese medicine preparation for treating liver cancer and preparation method thereof
CN103385993B (en) Chinese medicine preparation for treating gastric ulcer and preparation method thereof
CN103041257B (en) Chinese materia medica preparation for curing high fever and respiratory tract infection of children
CN104906465A (en) Traditional Chinese medicine blood-stasis dispersing composition for treating woman chronic pelvic inflammation and preparation method thereof
CN106039109A (en) Traditional Chinese medicinal liquor for preventing and treating cold dampness accumulation pattern rheumatoid arthritis
CN103495072B (en) Traditional Chinese medicine composition treating bronchiectasia disease and preparation method thereof
CN110025719A (en) A kind of Chinese medicinal formulae and preparation method thereof for treating lung cancer
CN105213876A (en) A kind of medicament for treating insomnia and preparation method thereof
CN103735906A (en) Chinese herb preparation for treating dry bronchiectasis and preparation method thereof
CN103520427A (en) Traditional Chinese medicine for treating body-resistance-weak and pathogen-strong type chronic osteomyelitis and preparation method thereof
CN103285161A (en) Anti-virus traditional Chinese medicinal composition and preparation method thereof
CN107744549A (en) A kind of medicine for treating toothache and preparation method thereof
CN106109895A (en) A kind of Chinese medicine composition treating phlegm stagnation fire type chronic pharyngitis and method
CN104873596A (en) Externally-applied traditional Chinese medicine lotion for treating eczema
CN105597004A (en) Traditional Chinese medicine combination for treating cancer
CN117379510A (en) Oral medicinal liquor and preparation method thereof
CN105079310A (en) Traditional Chinese medicine composition for relieving pain and method for preparing traditional Chinese medicine composition
CN114886959A (en) Pharmaceutical composition, preparation and application thereof
CN103860976A (en) Drug composition for treating infantile dermatitis
CN109820965A (en) It is a kind of to treat lung cancer cough, the Chinese medicine composition of asthma and its application

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190719