CN110025489A - A kind of Pifubing Xuedu Pill preparation general ball machine and Pifubing Xuedu Pill preparation process - Google Patents

A kind of Pifubing Xuedu Pill preparation general ball machine and Pifubing Xuedu Pill preparation process Download PDF

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Publication number
CN110025489A
CN110025489A CN201910353858.9A CN201910353858A CN110025489A CN 110025489 A CN110025489 A CN 110025489A CN 201910353858 A CN201910353858 A CN 201910353858A CN 110025489 A CN110025489 A CN 110025489A
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CN
China
Prior art keywords
xuedu
pifubing
control system
general ball
pill
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Granted
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CN201910353858.9A
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Chinese (zh)
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CN110025489B (en
Inventor
林忠泽
张清民
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Special Pharmaceutical Group Ltd By Share Ltd
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Special Pharmaceutical Group Ltd By Share Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/583—Snakes; Lizards, e.g. chameleons
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Abstract

The invention discloses a kind of Pifubing Xuedu Pill preparation general ball machine and Pifubing Xuedu Pill preparation processes, general ball equipment provided by the present invention has automatic whitewashing plus powder function, it can replace during general ball and spray into liquid adhesive and addition medicinal powder, it has been provided simultaneously with mass size detection device, it can be automatically stopped operation when the quality or partial size of pellet reach necessary requirement, meet the needs of modern industry large-scale production is to automation control；The production technology of the Pifubing Xuedu Pill is still further provided, processing step is reasonable, and traditional Chinese medicine extraction is abundant, and it is easy to operate, meet the demand that modern industry produces pill.

Description

A kind of Pifubing Xuedu Pill preparation general ball machine and Pifubing Xuedu Pill preparation process
Technical field
The present invention relates to pharmaceutical production fields, and in particular to a kind of Pifubing Xuedu Pill preparation general ball machine and dermopathic blood Poison pill preparation process.
Background technique
Dermatosis toxemia preparation is a kind of prescription medicine, and with blood-cleaning detoxifying, repellent antipruritic can be used in treating channels and collaterals not With, rubeola caused by damp and hot blood is dry, eczema, skin urtication, freckle as well as acne, flushing nose Cha, sore swollen toxin, tinea pedis scabies, the head Dizziness, dry feces.The party has very strong killing ability to the pathogenic microorganisms for causing human skin inflammation, therefore to infection Dermatoses can play the role of repairing and treating.It is antipruritic rapid, significant in efficacy.Diseased region epidermal cell angling can be delayed to be formed The scales of skin that peel off is significant to the therapeutic effect of psoriasis (psoriasis).Nosotoxin in elimination patient blood, internal organs, makes skin disease from root The effect of curing on this, do not stay future trouble, play external disease and internal treatment.Human immunological competence is improved, is allowed to not by dermopathic puzzlement.
In Chinese patent drug, dermatosis toxemia preparation is made generally in pill, i.e. Pifubing Xuedu Pill.Pill has in gastrointestinal tract In be slowly disintegrated, gradually discharge drug, persistent, the characteristics of reducing toxicity and adverse reaction, mostly controlling suitable for chronic disease Treatment or eipathia asthenia, the regulation of qi and blood is used after being ill.Classify according to preparation method, pill can be divided into modeling pill, general pill and drop Pill；Modeling pill, which refers to, is mixed and made into soft or hard suitable plasticity ball block for fine drug powder and suitable adhesive, then by its point It is cut into pellets；Generic method be fine drug powder is replaced with water or other liquid adhesives soak and be spread in suitable container or In machinery, constantly roll, a kind of method successively increased；Dripping ball, which refers to, will mainly dissolve, be suspended, be emulsified in a kind of fusing point compared with In low fatty or water-soluble base, it is added dropwise to pill made of condensing in a kind of not miscible liquid coolant.
Wherein general pill has small in size, and surface compact is smooth, and convenient for taking, easy disintegrating in vivo is quickly effective and be not easy The moisture absorption is conducive to save；Various drugs can be layered it is general enter, can not only cover its bad smell but can prevent fragrance ingredient volatilization etc. it is excellent Point is widely used, but generic method prepares pill and generally uses traditional artificial hand-made at present, and complicated operation, is not suitable with Industrial mass production is easy not met GMP related request by microbial contamination；Judgement in preparation process simultaneously mostly according to Rely people's micro-judgment, production batch differs greatly, and influences drug quality；Existing some general ball machines do not have automatic metaplasia still It produces, and the function of automation control, does not meet the demand of modern industrial production.
Summary of the invention
In view of the above shortcomings of the prior art, the present invention provides a kind of Pifubing Xuedu Pills to prepare general ball machine, with solution Certainly in the prior art artificial hand-made general pill it is cumbersome, vulnerable to microbial contamination, rely on people's micro-judgment and existing general ball The incomplete problem of machine function.
The present invention is reached above-mentioned purpose by the following technical programs:
The general ball machine of a kind of Pifubing Xuedu Pill preparation comprising host, rotation system and hot-air system；The host Including base, fuselage, pot body and pot angle regulating device；The fuselage is set on the base；The rotation system packet Decelerating motor and arbor are included, the decelerating motor is fixedly connected by arbor with the pot body；The hot-air system includes hot wind Machine and hot-air channel, hot-air channel outlet are set in pot body；The pot body and fuselage are living by the pot angle regulating device Dynamic connection；It further includes having hydrojet charging system, mass size detection device and control system；The control system respectively with The rotation system, hydrojet charging system, the electrical connection of mass size detection device；The hydrojet charging system include sprayer with And dusting device, outlet are set in the pot body；The mass size detection device is set in the pot body；The matter Amount droplet measurement device, which detects pill in pot body and will test signal, is transferred to the control system, the control system Signal and preset threshold are compared, when detecting signal greater than preset threshold, the control system can control described turn Dynamic system, hydrojet charging system stop working, and general ball step is completed.
Specifically, the mass size detection device includes support plate and several pressure sensors, the pressure sensing Device is connected by support arm with the support plate, and the support plate is fixedly connected with the pot body；The pressure sensor difference It is electrically connected to the control system, the pressure sensor carries out detection to the active force that pellet in pot body hits generation and will inspection It surveys signal and is transferred to the control system, the control system will test signal and compare with preset threshold, if setting, which is worked as, to be had When dry detection signal is greater than preset threshold, the control system controls the rotation system, hydrojet charging system stops working, General ball step is completed.
Further, the force signals that the pellet detected every time hits generation are transferred to institute by the pressure sensor Control system is stated, the control system handles data: for first pressure sensor A, successively detecting to obtain detection letter Number XA1, XA2…XAN, N is the natural number greater than 1, and the control system receives detection signal XANWhen, to XAN-L-XANTotal L+1 Detection signal carries out variance and variance S is calculatedN, L is no more than the natural number of N；Obtained variance S will be calculatedNWith predetermined threshold Value compares, and when it is less than preset threshold in allowable range of error, i.e., each pellet, which hits pressure sensor, to be generated Difference is smaller between the size of active force, pellet uniform particle sizes reach home, and the control system controls the rotation system System, hydrojet charging system stop working, and general ball step is completed.
Further, the mass size detection device is rotatably mounted in the pot body by an apparatus capable of fluctuating It is interior；The apparatus capable of fluctuating is connected with the control system, and the height of detection device is adjusted by control jacking system, is avoided Hydrojet dusting operation, which detects it, to be impacted.
Further, the apparatus capable of fluctuating be include upper backup pad, lower supporting plate, the first cylinder and the second cylinder；Institute Lower supporting plate is stated to be fixed in the pot body；The upper backup pad passes through first cylinder and the second cylinder and the lower support Plate connection, wherein the cylinder part of the first cylinder is hinged with lower supporting plate, tailpiece of the piston rod is hinged with upper backup pad；Second cylinder Cylinder part be fixed on lower supporting plate, tailpiece of the piston rod is hinged with upper backup pad；The pressure sensor is pacified by support arm On the upper backup pad, so that in the presence of cylinder, the mass size detection device can change angle, so as to more It is detected well.
Further, the dusting device includes a powder case and dust outlet, and the dust outlet and powder case are logical Cross powder duct connection；The dust outlet, which goes out, is provided with motor switch and sieve；The sprayer by fluid pipeline with External world's connection, convenient for being passed through liquid adhesive；The dusting device motor switch and sprayer switch respectively with control system Electrical connection；Powder is equably sprinkled into pot body by sieve, avoids agglomerating.
Further, the powder duct and fluid pipeline are carbon steel hose, can free bend, with work Actual conditions adjust outlet port.
Further, the pot body is made of high-quality stainless steel material, durable easy cleaning, while will not be to drug It pollutes.
Compared with the existing technology, Pifubing Xuedu Pill preparation provided by the present invention is provided with automatic control with general ball machine and hands over For adhesive and medicinal powder is added, the function of general system is carried out to pill in conjunction with pot body rotation, is additionally provided with hot-air system, it can be to general Temperature is controlled during system；In addition it is also configured with mass size detection device, according to grain during the general system of pill in pot body Linear relationship caused by shock of the mass change to pressure sensor caused by diameter becomes larger, when pill partial size reaches default threshold Value, general ball machine are automatically stopped；Further, by carrying out variance calculating to detection data, error can be efficiently reduced, into one Step improves detection accuracy, reaches the demand of automation control.
In addition, the present invention also provides a kind of preparation methods of Pifubing Xuedu Pill, specifically includes the following steps:
1) madder of required quality, peach kernel, ching-chieh (charcoal), snake slough, radix paeoniae rubra, Radix Angelicae Sinensis, rhizoma imperatae, the fruit of summer cypress, grey is weighed The ears or side handles of a utensil (stir-fry), glutinous rehmannia, Fructus Forsythiae, honeysuckle, corydlis bungeana, smilax, Cortex Phellodendri, spina gleditsiae, campanulaceae, motherwort, peeling fry semen armeniacae amarae, Radix saposhnikoviae, poria cocos, Radix Paeoniae Alba, cicada slough, great burdock achene, cortex moutan, cortex dictamni, Rehmannia glutinosa, Radix et Rhizoma Rhei (parched with wine), caulis lonicerae, Asian puccoon, native shellfish Mother, wine moxibustion Rhizoma Chuanxiong, Radix Glycyrrhizae, the root of Dahurain angelica, radix semiaquilegiae, Kadsura Root-bark, Caulis Spatholobi, duckweed, safflower totally three ten nine taste medicinal material are ground into thin Powder, sieving mix spare；
2) by a part of above-mentioned general ball machine pot body of fine powder obtained by step 1), another part is placed in the powder case；
3) general system: the rotation general ball machine, water is added for interval and powder is general that ball is made；When pellet rolls, to pot Internal mass size detection device generates random shock, and the mass size detection device is detected and be will test to impact force Signal is transferred to control system described in the general ball machine；The control system will test signal and be handled and be compared；Work as detection When signal meets preset requirement, general ball machine is automatically stopped；
4) dry: to take out and pellet is made, go in baking oven and be dried；
5) it is coated: the pellet after drying is transferred to coating pan, polishing agent is added and is coated, polishes to get dermopathic blood Poison pill.
Compared with the existing technology, Pifubing Xuedu Pill production technology provided by the present invention, operating procedure advantages of simple, It is abundant to the extraction of Chinese herbal medicine, the drug effect of drug can be given full play to；It is utilized simultaneously with automatic whitewashing plus powder, heating General ball machine is produced, and dependence hand-made to people in the prior art is got rid of, and has reached modernization pharmaceutical industries production It is required that；In addition the general ball machine also has mass size detection function and can be judged according to testing result, reaches automation The demand of control in order to better understand and implement, the invention will now be described in detail with reference to the accompanying drawings.
Detailed description of the invention
Fig. 1 is the apparatus structure schematic diagram that Pifubing Xuedu Pill described in embodiment 1 prepares general ball machine；
Fig. 2 is the structure of the detecting device schematic diagram
In Fig. 1: host 10；Rotation system 20；Hydrojet feeding device 30；Detection device 40；Hot-air system 50；
Host: base 11；Fuselage 12；Pot body 13；Pot angle regulating device 14；Adjusting knob 142；Pallet 15；
Rotation system: decelerating motor 21；Arbor 22；
Hydrojet feeding device: sprayer 31；Fluid pipeline 311；Liquid outlet 312；Dusting device 32；Powder case 321；Powder Last pipeline 322；Dust outlet 323；Bracket 324
Hot-air system: air-heater 51；Ventilation shaft 52；
In Fig. 2: detection device 40: pressure sensor 41；Support arm 42, apparatus capable of fluctuating 43；Upper backup pad 431, lower support Plate 432；First cylinder 433；Second cylinder 434；First articulated shaft 435；Second articulated shaft 436；Third articulated shaft 437.
Specific embodiment
Embodiment 1
It is the apparatus structure that Pifubing Xuedu Pill described in embodiment prepares general ball machine referring to Fig. 1 and Fig. 2, Fig. 1 Schematic diagram, Fig. 2 are the pot nside structural schematic diagrams that Pifubing Xuedu Pill described in the present embodiment prepares general ball machine.
The general ball machine of a kind of Pifubing Xuedu Pill preparation comprising host, rotation system, hydrojet charging system, detection dress It sets and control system (not shown)；The control system is electric with the rotation system, hydrojet charging system, detection device respectively Connection, can control the work of each system or device.
The host includes base, fuselage, pot body, pot angle regulating device and pallet；The fuselage is set to described On base；The pot body is connect with fuselage by the pot angle regulating device, and the pot angle regulating device can pass through rotation Turn button and adjust the pot body and connect with fuselage to be formed by angle.
The rotation system includes decelerating motor and arbor, and the decelerating motor is able to drive the rotation of arbor, the machine Axis is fixedly connected with the pot body.
The hydrojet charging system includes sprayer, dusting device；The sprayer is connect by fluid pipeline with the external world, For being passed through liquid adhesive；The dusting device includes powder case, powder duct, dust outlet and bracket, bracket to Powder case is supported, the dust outlet is connected by powder duct；The dust outlet, which goes out, is provided with motor switch and sieve Net.The sprayer switch is electrically connected with the control device respectively with dust outlet motor switch, the control system control Device is switched on and is closed.The fluid pipeline and powder duct are carbon steel bend pipe, can free bend, can be with work Make actual conditions adjustment outlet port.
The detection device is mass size detection device comprising several pressure sensors, the pressure sensor It is connected by support arm with the pot body.Further, the mass size detection device passes through apparatus capable of fluctuating rotatably It is fixed in the pot body, the pressure sensor is fixedly connected by support arm with the apparatus capable of fluctuating；The liftable dress It sets and is electrically connected with the control system, control system being capable of controller lifting；The apparatus capable of fluctuating be include upper backup pad, under Support plate, the first cylinder and the second cylinder；The lower supporting plate is fixed in the pot body；The upper backup pad passes through described the One cylinder and the second cylinder are connect with the lower supporting plate, wherein the cylinder part of the first cylinder and lower supporting plate are hinged, are lived Stopper rod end and upper backup pad are hinged；The cylinder part of second cylinder is fixed on lower supporting plate, tailpiece of the piston rod and upper backup pad Hingedly；The pressure sensor is mounted on the upper backup pad by support arm.
The hot-air system includes an air-heater and ventilation shaft, and the hot-air channel outlet is set in pot body, energy It is enough that material is heated simultaneously during general ball, it avoids generating the excessive phenomenon of pill moisture content.
When work, the rotation system decelerating motor rotation drives arbor and pot body to be rotated；The control system The starting of the spraying feeding device and detection device is controlled, constant duration alternately successively opens sprayer, dusting device And the switch of apparatus capable of fluctuating；When sprayer switch is opened, sprayer is by the liquid adhesive of fluid pipeline conveying, specifically For water, spray into pot body；Sprayer switch is closed immediately, is opened dusting device switch and is opened, dusting device passes through sieve toward pot It is sprinkled into quantitative medicinal powder in vivo；Extract powder is constantly bonded in rotation pot body, is gradually formed under the action of liquid adhesive Grain；By alternately spraying into liquid adhesive and being sprinkled into medicinal powder, grain diameter constantly increases.The control device close sprayer with And dusting device switch, and apparatus capable of fluctuating is controlled, direction is stretched out and changed to mass size detection device, towards pot body bottom Portion, preferably to be detected to the intracorporal drug granule of pot.The starting time of each device is to preset, can be according to reality Situation is adjusted.Drug wet granular liquid adhesive and medicinal powder be alternately added and the continuous rolling action of pot body under, quality Constantly become larger with partial size, it is general that ball is made.When pill constantly stirs in pot body, inevitably be set to the intracorporal matter of pot It measures droplet measurement device and random collision occurs, the work that collision can be generated when multiple pressure sensors and pellet collide It is firmly detected, and will test signal and be transferred to the control system；The pellet that the pressure sensor will detect every time It hits the force signals generated and is transferred to the control system, the control system handles data.When detection signal When greater than preset threshold, then it represents that the quality or particle size of pellet reach preset requirement at this time, that is, reach home, described default Threshold value be as pot nside be put into production batch finished product pellet tested obtained by.
Further, to avoid detection error, the control system handles detection signal: first pressure is passed Sensor A successively detects to obtain detection signal XA1, XA2…XAN, N is the natural number greater than 1, and the control system receives detection Signal XANWhen, to XAN-L-XANTotal L+1 detection signal carries out variance and variance S is calculatedN, L is the natural number no more than N；It will Count counted variance SNIt is compared with preset threshold, such as in the present embodiment, is set as carrying out variance meter to 3 detection signals Calculate, the preset threshold be as pot nside be put into production batch finished product pellet tested obtained by；Work as SNLess than pre- If when threshold value, i.e., each pellet is smaller to difference between the size of pressure sensor shock generation active force, pellet uniform particle sizes, It reaches home, the control system controls the rotation system, hydrojet charging system stops working, and general ball step is completed.
To be further reduced error, S is calculated to obtainNLater, to received detection signal XAN+1Same treatment is carried out, for XAN-L+1-XAN+1Total L+1 detection signal carries out identical calculations and obtains variance SN+1；By SN、SN+1It is compared with preset threshold, when Variance SNAnd SN+1It is respectively less than the predetermined value in allowable range of error, reaches home, the control system control is described to be turned Dynamic system, hydrojet charging system stop working, and general ball step is completed.
The mass size detection device can the principle that is detected of quality to pill and partial size it is as follows:
Under the action of liquid adhesive, with being continuously added for medicinal powder, the quality and partial size of pill constantly become larger；With The mass size of pill constantly increases, and collides generated active force with the pressure sensor of the mass size detection device Also it is increasing, is in a linear relationship.Therefore, for the pill of special formulation, for specific general ball machine, as long as throwing It is antenatal that general ball process is tested, detect different quality respectively, this kind of pellet of partial size does not stop rolling and institute in general ball machine It states mass size detection device to collide the amount of force of generation, and is fabricated to a working curve, therefore can be according to work The firmly linear relationship of the quality or partial size of size and pellet, can quality to pellet and partial size detect.
In addition, the present invention also provides a kind of Pifubing Xuedu Pill production technology using above-mentioned general ball machine, it is specific to wrap Include following steps:
1) madder of required quality, peach kernel, ching-chieh (charcoal), snake slough, radix paeoniae rubra, Radix Angelicae Sinensis, rhizoma imperatae, the fruit of summer cypress, grey is weighed The ears or side handles of a utensil (stir-fry), glutinous rehmannia, Fructus Forsythiae, honeysuckle, corydlis bungeana, smilax, Cortex Phellodendri, spina gleditsiae, campanulaceae, motherwort, peeling fry semen armeniacae amarae, Radix saposhnikoviae, poria cocos, Radix Paeoniae Alba, cicada slough, great burdock achene, cortex moutan, cortex dictamni, Rehmannia glutinosa, Radix et Rhizoma Rhei (parched with wine), caulis lonicerae, Asian puccoon, native shellfish Mother, wine moxibustion Rhizoma Chuanxiong, Radix Glycyrrhizae, the root of Dahurain angelica, radix semiaquilegiae, Kadsura Root-bark, Caulis Spatholobi, duckweed, safflower totally three ten nine taste medicinal material are ground into thin Powder, sieving mix spare；
2) fine powder a part obtained by step 1) is transferred in the general ball machine pot body, another part is placed in the powder case In；
3) general system: will rotate the general ball machine, and water is added for interval and powder is general that ball is made；It is right when pellet rolls Quality droplet measurement device generates random shock in pot body, and the mass size detection device carries out detection to impact force and will inspection It surveys signal and is transferred to control system described in the general ball machine；The control system will test signal and be handled and be compared；Work as inspection When survey signal meets preset requirement, general ball machine is automatically stopped；
4) dry: to take out and pellet is made, go in baking oven and be dried；
5) it is coated: the pellet after drying is transferred to coating pan, polishing agent is added and is coated, polishes to get dermopathic blood Poison pill.
Compared with the existing technology, general ball equipment provided by the present invention has automatic whitewashing plus powder function, can be in general ball Liquid adhesive and addition medicinal powder are alternately sprayed into the process, have been provided simultaneously with mass size detection device, it can be in the matter of pellet Amount or partial size are automatically stopped operation when reaching necessary requirement, meet the needs of modern industry large-scale production is to automation control； The production technology of the Pifubing Xuedu Pill is still further provided, processing step is reasonable, and traditional Chinese medicine extraction is abundant, easy to operate, symbol Close the demand that modern industry produces pill.
The invention is not limited to above embodiment, if not departing from the present invention to various changes or deformation of the invention Spirit and scope, if these changes and deformation belong within the scope of claim and equivalent technologies of the invention, then this hair It is bright to be also intended to encompass these changes and deformation.

Claims (9)

1. a kind of Pifubing Xuedu Pill prepares general ball machine comprising host, rotation system and hot-air system；The host packet Include base, fuselage, pot body and pot angle regulating device；The fuselage is set on the base；The rotation system includes Decelerating motor and arbor, the decelerating motor are fixedly connected by arbor with the pot body；The hot-air system includes air-heater And hot-air channel, hot-air channel outlet are set in pot body；The pot body and fuselage pass through the pot angle regulating device activity Connection,
It is characterized by also including have hydrojet charging system, mass size detection device and control system；The control system It is electrically connected respectively with the rotation system, hydrojet charging system, mass size detection device；The hydrojet charging system includes spray Day with fog and dusting device, outlet are set in the pot body；The mass size detection device is set in the pot body；
The mass size detection device, which detects pill in pot body and will test signal, is transferred to the control system, institute Control system is stated to compare signal and preset threshold, when detecting signal greater than preset threshold, the control system control The rotation system, hydrojet charging system stop working, and general ball step is completed.
2. Pifubing Xuedu Pill according to claim 1 prepares general ball machine, it is characterised in that: the mass size detection Device includes several pressure sensors, and the pressure sensor is connected by support arm with the pot body；The pressure sensing Device is electrically connected in the control system, and the pressure sensor hits the active force generated to pellet in pot body and detects And will test signal and be transferred to the control system, the control system will test signal and compare with preset threshold, setting When there is several detection signals to be greater than preset threshold, the control system controls the rotation system, hydrojet charging system is stopped It only works, general ball step is completed.
3. Pifubing Xuedu Pill according to claim 2 prepares general ball machine, it is characterised in that: the pressure sensor will The pellet detected every time hits the force signals generated and is transferred to the control system, and the control system carries out data Processing: for first pressure sensor A, detection signal X is successively detected to obtainA1, XA2…XAN, N is the natural number greater than 1, described Control system receives detection signal XANWhen, to XAN-L-XANTotal L+1 detection signal carries out variance and variance S is calculatedN, L is Natural number no more than N；Obtained variance S will be calculatedNIt is compared with predetermined threshold, when it is small in allowable range of error When predetermined threshold, i.e., each pellet is smaller to difference between the size of pressure sensor shock generation active force, pellet partial size Uniformly, that is, it reaches home, the control system controls the rotation system, hydrojet charging system stops working, and general ball step is complete At.
4. Pifubing Xuedu Pill according to claim 3 prepares general ball machine, it is characterised in that: the mass size detection Device is rotatably mounted in the pot body by an apparatus capable of fluctuating；The apparatus capable of fluctuating is connected with the control system It connects.
5. Pifubing Xuedu Pill according to claim 4 prepares general ball machine, it is characterised in that: the apparatus capable of fluctuating is Including upper backup pad, lower supporting plate, the first cylinder and the second cylinder；The lower supporting plate is fixed in the pot body；On described Support plate is connect by first cylinder and the second cylinder with the lower supporting plate, wherein the cylinder part of the first cylinder is under Support plate is hinged, and tailpiece of the piston rod is hinged with upper backup pad；The cylinder part of second cylinder is fixed on lower supporting plate, piston Rod end is hinged with upper backup pad；The pressure sensor is mounted on the upper backup pad by support arm.
6. Pifubing Xuedu Pill according to claim 1 prepares general ball machine, it is characterised in that: the dusting device includes One powder case and dust outlet, the dust outlet are connect with powder case by powder duct, and the powder duct is provided with Air pump；The dust outlet, which goes out, is provided with motor switch and sieve；The sprayer is connected with fluid pipeline, the liquid Peristaltic pump is provided on pipeline；The dusting device motor switch and sprayer switch are electrically connected to the control system respectively.
7. -6 any Pifubing Xuedu Pills prepare general ball machine according to claim 1, it is characterised in that: the powder tube Road and fluid pipeline are carbon steel hose.
8. -6 any Pifubing Xuedu Pills prepare general ball machine according to claim 1, it is characterised in that: the pot body is adopted It is made of high-quality stainless steel material.
9. a kind of Pifubing Xuedu Pill production technology, which comprises the following steps:
1) madder, the peach kernel, charcoal ching-chieh, snake slough, radix paeoniae rubra, Radix Angelicae Sinensis, rhizoma imperatae, the fruit of summer cypress, stir-baked FRUCCTUS XANTHII of required quality are weighed Stir-fry, glutinous rehmannia, Fructus Forsythiae, honeysuckle, corydlis bungeana, smilax, Cortex Phellodendri, spina gleditsiae, campanulaceae, motherwort, peeling fry semen armeniacae amarae, radix saposhnikoviae, Poria cocos, Radix Paeoniae Alba, cicada slough, great burdock achene, cortex moutan, cortex dictamni, Rehmannia glutinosa, Radix et Rhizoma Rhei (parched with wine), caulis lonicerae, Asian puccoon, the rhizoma bolbostemmae, wine moxibustion Rhizoma Chuanxiong, Radix Glycyrrhizae, the root of Dahurain angelica, radix semiaquilegiae, Kadsura Root-bark, Caulis Spatholobi, duckweed, safflower totally three ten nine taste medicinal material, are ground into fine powder, are sieved, It mixes spare；
2) molding: fine powder a part obtained by step 1) is transferred in any pot body of claim 1-6, another part is placed in institute It states in powder case；
3) general system: the rotation general ball machine, water is added for interval and herb powder is general that ball is made；When pellet rolls, to pot Internal mass size detection device generates random shock, and the mass size detection device is detected and be will test to impact force Signal is transferred to control system described in the general ball machine；The control system will test signal and be handled and be compared；Work as detection When signal meets preset requirement, general ball machine is automatically stopped；
4) dry: to take out and pellet is made, go in baking oven and be dried；
5) it is coated: the pellet after drying is transferred to coating pan, polishing agent is added and is coated, polishes to get Pifubing Xuedu Pill.
CN201910353858.9A 2019-04-29 2019-04-29 Pill making machine for preparing dermatosis blood virus pills and preparation process of dermatosis blood virus pills Active CN110025489B (en)

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CN2794512Y (en) * 2005-05-11 2006-07-12 闵金杆 Dripping tank pressure regulator for dripping pill machine
CN101032449A (en) * 2006-03-09 2007-09-12 陆洲 Novel technique of producing drop pills by pressing
CN202516005U (en) * 2012-05-11 2012-11-07 四川制药制剂有限公司 Spray closed coating machine with automatically controllable temperature in pan
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