CN109999127A - 祛腐生肌洗液 - Google Patents
祛腐生肌洗液 Download PDFInfo
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Abstract
本发明涉及肛门术后辅助治疗，特别是一种中药制剂药方进行痔疮等肛门处术后治疗的祛腐生肌洗液。祛腐生肌洗液，由包含下列重量配比的原料作为活性成份组成：苦参25‑35份，白鲜皮26‑34份，黄柏10‑20份，金银花5‑16份，大黄8‑20份，白芷10‑15份，花椒6‑17份，龙血竭粉13‑20份。解除肛门括约肌痉挛，改善局部血液循环，活血化瘀，消肿止痛，促进创面肉芽组织修复再生，加速创面愈合方面有很好的疗效。
Description
技术领域
本发明涉及肛门术后辅助治疗，特别是一种中药制剂药方进行痔疮等肛门处术后治疗的祛腐生肌洗液。
背景技术
痔疮疾病是一种最常见的多发疾病，大部分人都容易患上这种疾病，只是严重不严重的区别，患者表现为痔疮周围发痒，坐立不安，想要用手去抓蹭，有的患者甚至有异物感，痒痛难忍，不能饮酒和吃辛辣食品，有时甚至会影响到走路。大部分患者难以启齿，如厕时疼痛难忍，严重患者有经常出血现象，可导致贫血，影响日常生活与工作，目前西医只能采取手术进行治疗，手术后有部分患者还会复发，不能够完全彻底治愈。术后疼痛是手术患者存在的共同问题，痔疮手术因其部位特殊，术后疼痛直接影响病人的排便功能以及饮食、睡眠等。肛肠病术后疼痛，其病因病机为手术后经络受损气血运行不畅，导致局部血液循环受阻气血凝滞，运化失常所致。
发明内容
为了克服现有技术的上述缺点，本发明提供一种具有清热利湿、消肿止痛、止痒，用于痔疮肿痛及痔疮、肛痈术后患者的具有祛腐生肌作用的洗液，能减轻早期肛肠病患者疼痛，在解除术后患者肛门括约肌痉挛，改善局部血液循环、活血化瘀、消肿止痛、促进创面肉芽组织修复再生，加速创面愈合方面有很好的临床疗效。
本发明解决其技术问题所采用的技术方案是：祛腐生肌洗液，由包含下列重量配比的原料作为活性成份组成：苦参25-35份，白鲜皮26-34份，黄柏10-20份，金银花5-16份，大黄8-20份，白芷10-15份，花椒6-17份，龙血竭粉13-20份。
更优配方，苦参28-31份，白鲜皮29-32份，黄柏13-16份，金银花8-12份，大黄14-17份，花椒9-13份，白芷13-15份，龙血竭粉13-20份。
所述祛腐生肌洗液的制备工艺：将以上除龙血竭粉外药物按重量份加水800-1000份浸泡30分钟，放入密闭式煎药机中煎煮至温度110℃保持30分钟，即可将药液压出，过滤后加入龙血竭粉，用耐高温袋密封好，每袋200ml备用。所述煎药机采用加压密封的密闭式煎药机。
祛腐生肌洗液组方精练，配伍合理，具有清热利湿、消肿止痛、止痒，促进术后肛门伤口愈合的作用。方中苦参苦寒，清热燥湿，杀虫止痒；白鲜皮苦寒，有清热燥湿、泻火解毒、祛风止痒之功，外洗治疗伤口痒痛效果较好，两药同为君药。金银花甘寒，清热解毒、散痈消肿；黄柏苦寒，清热燥湿，泄火解毒，二者共为臣药，共同加强君药清热解毒作用。大黄苦寒，功用泻热毒，破积滞，行瘀血，治痈疡肿毒；白芷辛温，有消肿排脓、止痛之功；花椒除湿止痒，共为佐药，奏清热利湿、活血消肿、止痛、止痒之功。龙血竭粉具有活血散瘀，定痛止血，敛疮生肌的功效，用于跌打损伤，瘀血作痛，妇女气血凝滞，外伤出血，脓疮久不收口，以及慢性结肠炎所致的腹痛、腹泻等症。诸药合用，共奏清热解毒、散风消肿、止痛之功。
本发明具有以下有益效果：临床广泛使用至今，共治疗8000余例患者，有效率高于常规治疗药物，起效快，同时创面愈合时间更短。
祛腐生肌洗液在解除肛门括约肌痉挛，改善局部血液循环，活血化瘀，消肿止痛，促进创面肉芽组织修复再生，加速创面愈合方面有很好的疗效。在痔疮术后止痛、消肿、促进愈合方面疗效明显。祛腐生肌洗液的优点；缩短疼痛时间，促进伤口愈合，具有使用安全、疗效明显、方便、费用低的特点，值得推广使用。
具体实施方式
实施例1
祛腐生肌洗液，由包含下列重量配比的原料作为活性成份组成：苦参28份，白鲜皮29份，黄柏16份，金银花12份，大黄15份，花椒16份，白芷15份，龙血竭粉15份。
制备工艺，将以上除龙血竭粉外药物按重量份加水800-1000份浸泡30分钟，放入密闭式煎药机中煎煮至温度110℃保持30分钟，即可将药液压出，过滤后加入龙血竭粉，用耐高温袋密封好，每袋200ml备用。使用时，每次取一袋放入坐浴盆中，加1000ml温开水(温开水温度80-100℃)，先熏洗，后坐浴 (注意温度，避免烫伤)，每日1-2次，每次10-20分钟。
实施例2
祛腐生肌洗液，由包含下列重量配比的原料作为活性成份组成：苦参31份，白鲜皮32份，黄柏13份，金银花8份，大黄14份，花椒9份，白芷15份，龙血竭粉15份。
制备工艺，将以上除龙血竭粉外药物按重量份加水800-1000份浸泡30分钟，放入密闭式煎药机中煎煮至温度110℃保持30分钟，即可将药液压出，过滤后加入龙血竭粉，用耐高温袋密封好，每袋200ml备用。使用时，每次取一袋放入坐浴盆中，加1000ml温开水(温开水温度80-100℃)，先熏洗，后坐浴 (注意温度，避免烫伤)，每日1-2次，每次10-20分钟
实施例3
祛腐生肌洗液，由包含下列重量配比的原料作为活性成份组成：苦参30份，白鲜皮30份，黄柏15份，金银花10份，大黄15份，花椒10份，白芷15份，龙血竭15份。
制备工艺，将以上除龙血竭粉外药物按重量份加水800-1000份浸泡30分钟，放入密闭式煎药机中煎煮至温度110℃保持30分钟，即可将药液压出，过滤后加入龙血竭粉，用耐高温袋密封好，每袋200ml备用。使用时，每次取一袋放入坐浴盆中，加1000ml温开水(温开水温度80-100℃)，先熏洗，后坐浴 (注意温度，避免烫伤)，每日1-2次，每次10-20分钟。
术后疼痛是手术科室存在的共同问题。痔疮手术因其部位特殊，术后疼痛直接影响病人的排便功能以及饮食、睡眠等。本发明对痔疮术后患者用中药熏洗，缩短疼痛时间，促进伤口愈合具有明显的疗效。
1、一般资料:选择痔疮手术患者共348例。其中男性182例，女性166例；年龄 16-66岁，平均 37.4岁。所有患者为实施过痔疮手术的住院患者，在术后均有不同程度疼痛，病例随机分为两组，治疗组174例(祛腐生肌洗液组)，对照组174例。两组的一般资料相似，具有可比性。
2、治疗方法:两组患者，术后均使用抗菌药物，每日创口换药治疗，嘱软质饮食等常规治疗。对照组在常规治疗基础上使用高锰酸钾外洗；治疗组在常规治疗基础上加用祛腐生肌洗液熏洗患处。祛腐生肌洗液药物组成及用法：金银花10份，大黄15份，苦参30份，白鲜皮30份，黄柏15份，白芷15份，花椒10份，龙血竭粉20份。将以上除龙血竭粉外药物按重量份加水800份浸泡30分钟，放入密闭式煎药机中煎煮至温度110℃保持30分钟，即可将药液压出，过滤后加入龙血竭粉，用耐高温袋密封好，每袋200ml备用。
每次取一袋放入坐浴盆中，加1000ml温开水(温开水温度80-100℃)，先熏洗，后坐浴 (注意温度，避免烫伤)，每日1-2次，每次10-20分钟，7-l0天为l个疗程。
3、观察指标:创面愈合时间及用药后疼痛、水肿、出血、坠胀等主要症状体征减轻的程度。
4、治疗结果：
4.1 1个疗程结束后2组临床疗效比较见表1
注，总体有效率治疗组为93.68%，对照组为77.59%，经检验P<0.05；两组间有显著性差异，说明治疗组总体疗效优于对照组。
4.2两治疗组疼痛时间比较-见表2
注：从表中看出，治疗组疼痛时间明显少于对照组，尤其是3-5天的止痛效果明显优于对照组，差异有显著性意义（P<0.05）。
4.3两治疗组创面愈合时间比较-见表3
注：经t检验，P<0.05，说明两组患者创面愈合时间差异有显著意义，两治疗组患者创面愈合时间明显低于对照组。
治疗组在痔疮术后止痛、消肿、促进愈合方面明显优于对照组。祛腐生肌洗液的优点:缩短疼痛时间，伤口愈合早，具有安全、疗效明显、使用方便、费用低的特点，值得推广使用。
痔疮术后疼痛病因病机为手术后经络受损，气血运行不畅，导致局部血液循环受阻，气血凝滞，运化失常所致。治以清热燥湿、散瘀止痛。方中金银花，其性甘寒，气芳香，清热解毒，凉散风热，散痈消肿敛疮;现代研究证明具有抗菌及抗病毒、增强免疫功能、抗炎解毒作用。大黄清热泻火，止血，散风，苦寒沉降，入脾、胃、大肠经，有“将军”之称，泻实火，破瘀血，祛瘀同时具有止痛功效；现代研究证明，大黄有很强的抗感染、抗衰老、抗氧化作用，能够调节免疫功能、抗炎、解热、抗病原微生物作用，对多种革兰阳性和阴性细菌均有抑制作用。苦参、黄柏清热燥湿清肠。白芷祛风止痛，本品具有镇静镇痛、抗炎作用。白鲜皮、花椒等燥湿温中，散寒止痛。
诸药合用，共奏清热解毒、散风消肿止痛之功。祛腐生肌洗液在解除肛门括约肌痉挛，改善局部血液循环，活血化瘀，消肿止痛，促进创面肉芽组织修复再生，加速创面愈合方面有很好的疗效。在痔疮术后止痛、消肿、促愈方面疗效明显优于对照组。
Claims (4)
1.祛腐生肌洗液，由包含下列重量配比的原料作为活性成份组成：苦参25-35份，白鲜皮26-34份，黄柏10-20份，金银花5-14份，大黄8-20份，花椒6-17份，白芷10-15份，龙血竭粉13-20份。
2.如权利要求1所述祛腐生肌洗液，其特征在于：苦参28-30份，白鲜皮29-32份，黄柏11-14份，金银花9-12份，大黄14-17份，花椒9-13份，白芷13-15份，龙血竭粉13-20份。
3.如权利要求1或2所述祛腐生肌洗液的制备工艺，其特征在于：将以上除龙血竭粉外药物按重量份加水800-1000份浸泡30分钟，放入密闭式煎药机中煎煮至温度110℃保持30分钟，即可将药液压出，过滤后加入龙血竭粉，用耐高温袋密封好，每袋200ml备用。
4.如权利要求3所述祛腐生肌洗液的制备工艺，其特征在于：所述煎药机采用加压密闭式煎药机。
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| 张天武: "中药熏洗方治疗痔瘘疾病108例", 《中国民间疗法》 * |
| 张天武: "血竭粉在肛瘘术后换药中的运用体会", 《中国现代医生》 * |
| 张天武等: "自拟银黄洗液熏洗治疗痔疮术后疼痛的效果研究", 《中国民间疗法》 * |
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