CN109999118A - A kind of preparation method of rhizoma pinellinae praeparata - Google Patents
A kind of preparation method of rhizoma pinellinae praeparata Download PDFInfo
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- CN109999118A CN109999118A CN201910315979.4A CN201910315979A CN109999118A CN 109999118 A CN109999118 A CN 109999118A CN 201910315979 A CN201910315979 A CN 201910315979A CN 109999118 A CN109999118 A CN 109999118A
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- pinellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
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Abstract
The invention discloses a kind of preparation methods of rhizoma pinellinae praeparata, and its step are as follows: picking out the impurity in the tuber of pinellia on the table, obtain the net tuber of pinellia；The net tuber of pinellia is subjected to screening stepping；The tuber of pinellia after net system stepping is cleaned up in medicine-washing machine respectively；Clear water impregnates, and the tuber of pinellia after stepping is cleaned is respectively placed in medicine processing device to be impregnated with water, when in the tuber of pinellia without the dry heart, takes out spare；Radix Glycyrrhizae limewash is prepared, appropriate extracting liquorice adds water to cook secondary, collecting decoction；Quick lime is modulated with clear water simultaneously, lime liquor is made, and stir evenly；Then Radix Glycyrrhizae decocting liquid obtained is poured into lime liquor, is stirred evenly, it is spare；Radix Glycyrrhizae limewash impregnates, and the tuber of pinellia after clear water is impregnated pours into Radix Glycyrrhizae limewash obtained, stirs evenly, and impregnates, until section yellow homogeneous, mouth is tasted micro- when having numb feeling in the tongue, takes out；High production efficiency of the present invention, with short production cycle, simple process, easy to operate, concocting process convenient for control, be conducive to industrialized production.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, and in particular to a kind of preparation method of rhizoma pinellinae praeparata.
Background technique
The tuber of pinellia, Araeceae medicinal plant, medicinal part are stem tuber；Yu Xia, Qiu Liangji cauline leaf are excavated when luxuriant, are removed outer
Skin and fibrous root are dried or are dried, as dried pinellia；Dry tuber is rounded, semicircle is spherical or deflection shape, diameter 0.8-2cm；
Superficial white is faint yellow；Matter is solid, fine and close.It is its acrid flavour, warm-natured, it is toxic；Returns spleen, stomach, lung channel；Primary efficacy and effect are:
Eliminating dampness and eliminating phlegm, drop check is spat, dissolving lump and resolving mass；Wet phlegm and cold drink is controlled, is vomitted, gastric disorder causing nausea, cough and phlegm, fullness in chest, phlegm and headache, head
Dizzy egersis；Outer subduing inflammation.
Tuber of pinellia complete stool is toxic, and wherein stem tuber is more toxic, and eating 0.1-1.8g raw can cause to be poisoned；To oral cavity, larynx, disappear
Intense stimulus can be caused by changing road mucous membrane；Clothes can make dispute numb on a small quantity, volume then Burning Pain swelling, be unable to sounding, vomiting, whole body
Numb, oligopnea is finally benumbed and dead without whole, spasm, expiratory dyspnea；Taking dried pinellia volume can lead to permanent aphonia；Cause
Toxicity of Rhizoma Pinelliae is larger, need to use after processing, and is divided into rhizoma pinellinae praeparata, rhizoma pinellinae praeparata, rhizoma pinellinae praeparata etc. according to concocting method difference.
Currently, the concocting method of rhizoma pinellinae praeparata is method as defined in 2015 editions " Chinese Pharmacopoeia ", by the method for pharmacopeia, only greatly
Describe production rhizoma pinellinae praeparata process with causing, does not disclose the detail of the processings such as the selection of raw material, thus present city
There is quite a few rhizoma pinellinae praeparata to only reach standards of pharmacopoeia on face, and concocting process is not easy to grasp, and is unfavorable for industrialized production, if
In concocting process, tightened up regulation is made to the Key detail of each process, and the quality of rhizoma pinellinae praeparata can be improved, make concocting process
It is more controllable, it is conducive to industrialized production.
Summary of the invention
To solve the above problems, the present invention provides a kind of preparation method of rhizoma pinellinae praeparata, the preparation process high production efficiency, life
Produce the period is short, simple process, easy to operate, concocting process convenient for control, be conducive to industrialized production.
The present invention is achieved through the following technical solutions: a kind of preparation method of rhizoma pinellinae praeparata, its step are as follows:
Step 1, net system picks out the impurity in the tuber of pinellia on the table, obtains the net tuber of pinellia；
Step 2, the net tuber of pinellia in step 1 is carried out screening stepping by stepping, spare；
Step 3, it cleans, the tuber of pinellia after net system stepping in step 2 is cleaned up in medicine-washing machine respectively；
Step 4, clear water impregnates, and the tuber of pinellia after stepping cleaning in step 4 is respectively placed in medicine processing device and is impregnated with water, until
When in the tuber of pinellia without the dry heart, take out spare；
Step 5, Radix Glycyrrhizae limewash is prepared, appropriate extracting liquorice adds water to cook secondary, collecting decoction；Simultaneously by quick lime clear water
Modulation is made lime liquor, and stirs evenly；Then Radix Glycyrrhizae decocting liquid obtained is poured into lime liquor, is stirred evenly, it is spare；
Step 6, Radix Glycyrrhizae limewash impregnates, and the tuber of pinellia after impregnating in step 4 is poured into step 5 in Radix Glycyrrhizae limewash obtained,
It stirs evenly, impregnates, until section yellow homogeneous, mouth is tasted micro- when having numb feeling in the tongue, takes out；
Step 7, it cleans, is rinsed well the tuber of pinellia that Radix Glycyrrhizae limewash impregnated in step 6 with clear water, it is spare；
Step 8, dry, the tuber of pinellia cleaned up in step 7 is dried, and medicine bits are weeded out after cooling；
Step 9, it packs, detect, storage.
It is first placed in hold-up vessel after the completion of each step, carries out next step again after the assay was approved.
The hold-up vessel is plastic container or stainless steel barrel, and the condition of storage is temperature: 10~30 DEG C, relatively wet
Degree: 45~75%.
The temperature that clear water impregnates in the step 4 is room temperature, and the soaking time of summer is 3-4 days, when the immersion in winter
Between be 7-8 days, and in soaking process, change daily water 2-3 times.
The temperature that Radix Glycyrrhizae limewash impregnates in the step 6 is room temperature, and the soaking time of summer is 2-3 days, winter
Soaking time is 6-7 days, and in soaking process, daily stirring 1-2 times, and keeps immersion liquid pH value 12 or more.
In the step 7, the tuber of pinellia is cleaned with circulating water.
In the step 8, dried by uniformly spreading out the tuber of pinellia piece after the tuber of pinellia after drying or cutting to set in hot air circulation
It is dried in case stainless steel pallet.
The described tuber of pinellia booth set with a thickness of 1.5~2.5cm.
The dry temperature of the tuber of pinellia is 60 ~ 80 DEG C in the step 8, and the dry time is 5 ~ 7 hours, and moisture must not exceed
13%。
The quality proportioning relationship of the net tuber of pinellia, Radix Glycyrrhizae and quick lime are as follows: 20:3:2.
The beneficial effects of the present invention are: methods of the invention to specify the tuber of pinellia in each leaching drift time for processing process, sweet
The details such as the manufacturing process of grass juice factor and limewash, and dry temperature range, for reducing the toxicity of rhizoma pinellinae praeparata, improving it
Curative effect is of great significance；Preparation process of the invention largely uses mechanized operation, and production process is easily controllable, realizes
Automation, scale and the standardization of production；Resulting rhizoma pinellinae praeparata is processed through the method for the present invention, character identifies, thin layer identifies, water
Point, the indices such as total ash, extract meet the pertinent regulations in 2015 version " Chinese Pharmacopoeia " (one).
Specific embodiment
The present invention is further explained in the light of specific embodiments:
Embodiment 1
A kind of preparation method of rhizoma pinellinae praeparata, its step are as follows:
Step 1, net system picks out the impurity in the tuber of pinellia on the table, obtains the net tuber of pinellia；
Step 2, the net tuber of pinellia in step 1 is carried out screening stepping by stepping, spare；
Step 3, it cleans, the tuber of pinellia after net system stepping in step 2 is cleaned up in medicine-washing machine respectively；
Step 4, clear water impregnates, and the tuber of pinellia after stepping cleaning in step 4 is respectively placed in medicine processing device and is impregnated with water, until
When in the tuber of pinellia without the dry heart, take out spare；
Step 5, Radix Glycyrrhizae limewash is prepared, appropriate extracting liquorice adds water to cook secondary, collecting decoction；Simultaneously by quick lime clear water
Modulation is made lime liquor, and stirs evenly；Then Radix Glycyrrhizae decocting liquid obtained is poured into lime liquor, is stirred evenly, it is spare；
Step 6, Radix Glycyrrhizae limewash impregnates, and the tuber of pinellia after impregnating in step 4 is poured into step 5 in Radix Glycyrrhizae limewash obtained,
It stirs evenly, impregnates, until section yellow homogeneous, mouth is tasted micro- when having numb feeling in the tongue, takes out；
Step 7, it cleans, is rinsed well the tuber of pinellia that Radix Glycyrrhizae limewash impregnated in step 6 with clear water, it is spare；
Step 8, dry, the tuber of pinellia cleaned up in step 7 is dried, and medicine bits are weeded out after cooling；
Step 9, it packs, detect, storage.
Method of the invention specifies the tuber of pinellia in the production of each leaching drift time, succus liquiritiae and limewash for processing process
The details such as journey, and dry temperature range are of great significance for reducing the toxicity of rhizoma pinellinae praeparata, improving its curative effect；This hair
Bright preparation process largely uses mechanized operation, can control the parameters of the processing procedure of rhizoma pinellinae praeparata well, improves method
The quality of tuber of pinellia product, processing method is easy to operate, shortens production cycle and supplementary product consumption, saves production cost, is suitble to industry
Change large-scale production, effectively overcomes and need to control by experience in the prior art, be not easy to grasp, be difficult to lacking for industrialized production
It falls into.
Embodiment 2
A kind of preparation method of rhizoma pinellinae praeparata, its step are as follows:
Step 1, net system picks out the impurity in the tuber of pinellia on the table, obtains the net tuber of pinellia；
Step 2, the net tuber of pinellia in step 1 is carried out screening stepping by stepping, spare；
Step 3, it cleans, the tuber of pinellia after net system stepping in step 2 is cleaned up in medicine-washing machine respectively；
Step 4, clear water impregnates, and the tuber of pinellia after stepping cleaning in step 4 is respectively placed in medicine processing device and is impregnated with water, until
When in the tuber of pinellia without the dry heart, take out spare；
Step 5, Radix Glycyrrhizae limewash is prepared, appropriate extracting liquorice adds water to cook secondary, collecting decoction；Simultaneously by quick lime clear water
Modulation is made lime liquor, and stirs evenly；Then Radix Glycyrrhizae decocting liquid obtained is poured into lime liquor, is stirred evenly, it is spare；
Step 6, Radix Glycyrrhizae limewash impregnates, and the tuber of pinellia after impregnating in step 4 is poured into step 5 in Radix Glycyrrhizae limewash obtained,
It stirs evenly, impregnates, until section yellow homogeneous, mouth is tasted micro- when having numb feeling in the tongue, takes out；
Step 7, it cleans, is rinsed well the tuber of pinellia that Radix Glycyrrhizae limewash impregnated in step 6 with clear water, it is spare；
Step 8, dry, the tuber of pinellia cleaned up in step 7 is dried, and medicine bits are weeded out after cooling；
Step 9, it packs, detect, storage.
It is first placed in hold-up vessel after the completion of each step, carries out next step again after the assay was approved.
The hold-up vessel is plastic container or stainless steel barrel, and the condition of storage is temperature: 10~30 DEG C, relatively wet
Degree: 45~75%.
The temperature that clear water impregnates in the step 4 is room temperature, and the soaking time of summer is 3-4 days, when the immersion in winter
Between be 7-8 days, and in soaking process, change daily water 2-3 times.
The temperature that Radix Glycyrrhizae limewash impregnates in the step 6 is room temperature, and the soaking time of summer is 2-3 days, winter
Soaking time is 6-7 days, and in soaking process, daily stirring 1-2 times, and keeps immersion liquid pH value 12 or more.
In the step 7, the tuber of pinellia is cleaned with circulating water.
In the step 8, dried by uniformly spreading out the tuber of pinellia piece after the tuber of pinellia after drying or cutting to set in hot air circulation
It is dried in case stainless steel pallet.
The described tuber of pinellia booth set with a thickness of 1.5~2.5cm.
The dry temperature of the tuber of pinellia is 60 ~ 80 DEG C in the step 8, and the dry time is 5 ~ 7 hours, and moisture must not exceed
13%。
The quality proportioning relationship of the net tuber of pinellia, Radix Glycyrrhizae and quick lime are as follows: 20:3:2.
Method of the invention specifies the tuber of pinellia in the production of each leaching drift time, succus liquiritiae and limewash for processing process
The details such as journey, and dry temperature range are of great significance for reducing the toxicity of rhizoma pinellinae praeparata, improving its curative effect；This hair
Bright preparation process largely uses mechanized operation, can control the parameters of the processing procedure of rhizoma pinellinae praeparata well, improves method
The quality of tuber of pinellia product, processing method is easy to operate, shortens production cycle and supplementary product consumption, saves production cost, is suitble to industry
Change large-scale production, effectively overcomes and need to control by experience in the prior art, be not easy to grasp, be difficult to lacking for industrialized production
It falls into.
Claims (10)
1. a kind of preparation method of rhizoma pinellinae praeparata, which is characterized in that its step are as follows:
Step 1, net system picks out the impurity in the tuber of pinellia on the table, obtains the net tuber of pinellia；
Step 2, the net tuber of pinellia in step 1 is carried out screening stepping by stepping, spare；
Step 3, it cleans, the tuber of pinellia after net system stepping in step 2 is cleaned up in medicine-washing machine respectively；
Step 4, clear water impregnates, and the tuber of pinellia after stepping cleaning in step 4 is respectively placed in medicine processing device and is impregnated with water, until
When in the tuber of pinellia without the dry heart, take out spare；
Step 5, Radix Glycyrrhizae limewash is prepared, appropriate extracting liquorice adds water to cook secondary, collecting decoction；Simultaneously by quick lime clear water
Modulation is made lime liquor, and stirs evenly；Then Radix Glycyrrhizae decocting liquid obtained is poured into lime liquor, is stirred evenly, it is spare；
Step 6, Radix Glycyrrhizae limewash impregnates, and the tuber of pinellia after impregnating in step 4 is poured into step 5 in Radix Glycyrrhizae limewash obtained,
It stirs evenly, impregnates, until section yellow homogeneous, mouth is tasted micro- when having numb feeling in the tongue, takes out；
Step 7, it cleans, is rinsed well the tuber of pinellia that Radix Glycyrrhizae limewash impregnated in step 6 with clear water, it is spare；
Step 8, dry, the tuber of pinellia cleaned up in step 7 is dried, and medicine bits are weeded out after cooling；
Step 9, it packs, detect, storage.
2. a kind of preparation method of rhizoma pinellinae praeparata according to claim 1, it is characterised in that: be first placed in after the completion of each step
In hold-up vessel, next step is carried out again after the assay was approved.
3. a kind of preparation method of rhizoma pinellinae praeparata according to claim 2, it is characterised in that: the hold-up vessel is plastics
Turnover box or stainless steel barrel, the condition of storage are temperature: 10~30 DEG C, relative humidity: 45~75%.
4. a kind of preparation method of rhizoma pinellinae praeparata according to claim 1, it is characterised in that: clear water soaks in the step 4
The temperature of bubble is room temperature, and the soaking time of summer is 3-4 days, and the soaking time in winter is 7-8 days, and in soaking process, often
Day changes water 2-3 times.
5. a kind of preparation method of rhizoma pinellinae praeparata according to claim 1, it is characterised in that: Radix Glycyrrhizae stone in the step 6
The temperature that buck impregnates is room temperature, and the soaking time of summer is 2-3 days, and the soaking time in winter is 6-7 days, and in soaking process
In, daily stirring 1-2 times, and keep immersion liquid pH value 12 or more.
6. a kind of preparation method of rhizoma pinellinae praeparata according to claim 1, it is characterised in that: in the step 7, with flowing
Water cleans the tuber of pinellia.
7. a kind of preparation method of rhizoma pinellinae praeparata according to claim 1, it is characterised in that: in the step 8, pass through by
The tuber of pinellia piece after the tuber of pinellia or cutting after drying uniformly spreads out to set to be dried in heated-air circulation oven stainless steel pallet.
8. a kind of preparation method of rhizoma pinellinae praeparata according to claim 7, it is characterised in that: the tuber of pinellia spreads out the thickness set
For 1.5~2.5cm.
9. a kind of preparation method of rhizoma pinellinae praeparata according to claim 1 or 6, it is characterised in that: the tuber of pinellia in the step 8
Dry temperature is 60 ~ 80 DEG C, and the dry time is 5 ~ 7 hours, and moisture must not exceed 13%.
10. a kind of preparation method of rhizoma pinellinae praeparata according to claim 1, it is characterised in that: the net tuber of pinellia, Radix Glycyrrhizae and
The quality proportioning relationship of quick lime are as follows: 20:3:2.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111643587A (en) * | 2020-06-17 | 2020-09-11 | 潜江市潜半夏药业股份有限公司 | Processing method of rhizoma pinellinae praeparata |
| CN112641858A (en) * | 2021-02-02 | 2021-04-13 | 湖北道地药材科技有限公司 | Processing technology of rhizoma pinellinae praeparata |
| CN118189604A (en) * | 2024-04-22 | 2024-06-14 | 绍兴震元中药饮片有限公司 | Drying device for processing rhizoma pinellinae praeparata and processing production process of rhizoma pinellinae praeparata |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101711825A (en) * | 2009-10-10 | 2010-05-26 | 北京同仁堂（亳州）饮片有限责任公司 | Preparation method of rhizoma pinelliae preparata |
| CN105663527A (en) * | 2016-02-26 | 2016-06-15 | 江西青春康源中药饮片有限公司 | Processing method suitable for rhizoma pinellinae praeparata and rhizoma typhonii flagelliformis |
| CN109381579A (en) * | 2018-12-25 | 2019-02-26 | 广州市药材公司中药饮片厂 | A kind of Preparation process method of rhizoma pinellinae praeparata |
-
2019
- 2019-04-19 CN CN201910315979.4A patent/CN109999118A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101711825A (en) * | 2009-10-10 | 2010-05-26 | 北京同仁堂（亳州）饮片有限责任公司 | Preparation method of rhizoma pinelliae preparata |
| CN105663527A (en) * | 2016-02-26 | 2016-06-15 | 江西青春康源中药饮片有限公司 | Processing method suitable for rhizoma pinellinae praeparata and rhizoma typhonii flagelliformis |
| CN109381579A (en) * | 2018-12-25 | 2019-02-26 | 广州市药材公司中药饮片厂 | A kind of Preparation process method of rhizoma pinellinae praeparata |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111643587A (en) * | 2020-06-17 | 2020-09-11 | 潜江市潜半夏药业股份有限公司 | Processing method of rhizoma pinellinae praeparata |
| CN112641858A (en) * | 2021-02-02 | 2021-04-13 | 湖北道地药材科技有限公司 | Processing technology of rhizoma pinellinae praeparata |
| CN118189604A (en) * | 2024-04-22 | 2024-06-14 | 绍兴震元中药饮片有限公司 | Drying device for processing rhizoma pinellinae praeparata and processing production process of rhizoma pinellinae praeparata |
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Application publication date: 20190712 |