CN109985676A - A kind of Multi-channel liquid sample collection storage device suitable for hand-held SPR detector - Google Patents
A kind of Multi-channel liquid sample collection storage device suitable for hand-held SPR detector Download PDFInfo
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- CN109985676A CN109985676A CN201910335249.0A CN201910335249A CN109985676A CN 109985676 A CN109985676 A CN 109985676A CN 201910335249 A CN201910335249 A CN 201910335249A CN 109985676 A CN109985676 A CN 109985676A
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- 239000007788 liquid Substances 0.000 title claims abstract description 125
- 239000003153 chemical reaction reagent Substances 0.000 claims description 18
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- 238000001914 filtration Methods 0.000 claims description 4
- 238000007689 inspection Methods 0.000 claims description 2
- 238000005070 sampling Methods 0.000 claims description 2
- 238000001514 detection method Methods 0.000 abstract description 18
- 238000012360 testing method Methods 0.000 abstract description 8
- 239000012530 fluid Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
- G01N21/553—Attenuated total reflection and using surface plasmons
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
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Abstract
The invention discloses a kind of Multi-channel liquid sample collection storage devices suitable for hand-held SPR detector, including liquid sample collecting device and liquid sample storage device；Liquid sample collecting device includes multiple liquid sample collectors；Liquid sample storage device, including storage device shell, storage device enclosure interior are provided with multiple acquisition device storage chambers, and each acquisition device storage chamber lower end is provided with the interface arrangement for connecting with SPR detector adding mouth.The present invention can either well store multiple testing liquid samples, and Multi-channel liquid pattern detection operation can be carried out on SPR detector, improve SPR detection efficiency.
Description
Technical field
The present invention relates to a kind of sample collection storage devices more particularly to a kind of suitable for the more of hand-held SPR detector
Channel liquid sample collection storage device.
Background technique
Surface plasma resonance (SPR) is a kind of physical optics phenomenon.In two kinds of different refractivity (refractive
Index on transparent medium interface) (such as glass and water), it is situated between when Ray Of Light is incident on low-refraction from high refractive index medium
Matter, light will occur to reflect and reflect.When incidence angle increases to a certain particular value, refraction angle be equal to 90 °, this time along with
The tangent direction in interface is projected, and incidence angle at this time is known as critical angle.If incidence angle is more than critical angle, incident ray will not
Another transfer can be entered, and be all reflected back toward in incident medium, experiences total internal reflection.
In fact, although whole incident light is reflected, a kind of electromagnetic field being evanescent wave can pass through contacting permeation to low folding
It penetrates in rate medium, energy is exponentially decayed.If plating one layer of metallic film (general gold-plated film or silverskin), metal in interface
The free electron of film surface is excited by incident light and generates charge oscillation, and then forms surface plasma.Adjustment light enters
When firing angle or wavelength are to a certain appropriate value, surface plasma is equal with the frequency of evanescent wave and wave number, and energy just occurs for the two
Coupling forms surface plasma resonance.The total reflection condition of interface will be destroyed when resonance, and incident laser energy is transferred to table
In surface plasma wave, sharply decline in the air so as to cause intensity of reflected light, decaying total reflection phenomenon is presented.Wherein make anti-
It penetrates the incident light angle that light completely disappears and is known as resonance angle (SPR angle).Resonance angle can be with the medium of metal film surfaces
The change of refractive index and change, and refractive index variation it is directly proportional to the quality for the molecule for being incorporated in metal surface.Therefore pass through
Analyze resonance angle, so that it may obtain the information of intermolecular interaction.
SPR sensorgram technology, which has without label, to surface characteristic and substance, changes sensitivity, in real time, quickly and easily realizes
The features such as automation.The technology has been widely used in life science, clinical diagnosis, drug screening, food safety, environmental monitoring
Equal fields, test object includes albumen, nucleic acid, hormone, toxin, pesticide, cell, microorganism etc..
Application No. is the patents of CN2016213963168 to disclose a kind of hand-held SPR bio-detector, including shell,
It equipped with light incidence component, light-receiving component and light for receiving the sending of light incidence component and is reflexed to light and is connect in shell
The light reflection subassembly of component is received, light reflection subassembly includes reflecting prism, the sensing chip on the reflecting surface of reflecting prism, is passed
Sense chip includes substrate and gold-plated sheet glass, and the substrate is equipped with loading slot, negative pressure chamber and is used for loading slot and bears
The sample runner that pressure chamber is connected.Light incidence component, light-receiving component and light reflection subassembly are fixed in shell by the present invention,
Wavelength, angle and the intensity that incident light can be fixed avoid the turntable design of the SPP instrument of large scale business in the market, whole
Body structure is more simple, easily operated, so that product of the present invention is small in size.
In above-mentioned patent, on the one hand, when testing liquid sample is added, need to take out sensing chip, and in exposure ring
Testing liquid sample is instilled in loading slot under border, it is inconvenient, it also will cause testing liquid sample contamination.Simultaneously as real
Border generally requires to store liquid sample to be measured when working, and detects followed by SPR.On the other hand, existing hand-held
Formula SPR detector is only capable of once carrying out SPR detection for a sample, and detection efficiency is lower.
Therefore being badly in need of one kind can well store to multiple survey liquid samples, while be suitable for hand-held SPR detector
Multi-channel liquid sample collection storage device efficiently carries out SPR detection convenient for user.
Summary of the invention
The object of the present invention is to provide a kind of Multi-channel liquid sample collections suitable for hand-held SPR detector to store dress
It sets, can either well store multiple testing liquid samples, and Multi-channel liquid pattern detection behaviour can be carried out on SPR detector
Make, improves SPR detection efficiency.
The present invention adopts the following technical solutions:
A kind of Multi-channel liquid sample collection storage device suitable for hand-held SPR detector, including liquid sample acquisition dress
It sets and liquid sample storage device；
The liquid sample collecting device, including multiple liquid sample collectors, the upper end opening of liquid sample collector be
Collector sample tap, liquid sample collector are internally provided with storage chamber, and the lower end of liquid sample collector is provided with and deposits
The collector outlet of storage chamber conducting, is provided with collector sample tap plugging device, collector outlet on collector sample tap
On be provided with collector outlet plugging device；
The liquid sample storage device, including storage device shell, storage device enclosure interior are provided with multiple acquisition dresses
Storage chamber is set, each liquid sample collecting device is all made of removably and is correspondingly arranged in each acquisition device storage chamber,
Each acquisition device storage chamber lower end is provided with collector outlet connecting tube, and each collector outlet connecting tube passes through
The U-shaped channel that storage device enclosure interior is arranged in is connected with interface arrangement for connecting with SPR detector adding mouth, corresponding
Collector outlet connecting tube, U-shaped channel and interface arrangement conducting, be provided with interface plugging device in interface arrangement；Each
It is provided with connecting pipe head accommodation groove below interface arrangement, the two sides of connecting pipe head accommodation groove offer sliding groove, connecting tube
The sliding shoe that head is arranged by connecting pipe head two sides is slidably connected with connecting pipe head accommodation groove, and SPR inspection is provided in connecting pipe head
Survey the connecting cavity that instrument sample-adding mouth-shaped matches.
The liquid sample collector is tubular, and collector sample tap inner surface is provided with internal screw thread, collector sampling
Mouth plugging device is cylindrical sealing-plug, is provided with and the matched outer spiral shell of collector sample tap internal screw thread on the outside of sealing-plug
Line, sealing-plug are threadedly coupled with collector sample tap；The middle part of sealing-plug is axially disposed threaded hole, is provided in threaded hole
Push rod, the lower part of push rod are provided with thread segment, and the diameter of thread segment is greater than rod diameter, and the lower end of thread segment is connected with and stores
The rubber stopper that chamber matches, storage chamber are slidably connected with storage chamber.
Filter device is provided in the storage chamber, filter device includes filter holder and the first filter screen, filtering branch
Frame includes the mounting ring to match with storage chamber, the first filter screen is provided in mounting ring, there are two branch for the setting of mounting ring lower part
The outer surface of leg, mounting ring is provided with rubber layer.
The outlet plugging device and interface plugging device is all made of rubber film.
The collector outlet connecting tube is vertically arranged and end is provided with sharp portion, acquisition device storage chamber bottom
It is additionally provided with the limiting slot to match with collector outlet outer diameter, the shape of limiting slot and collector outlet matches.
The acquisition device storage inner cavity surface is provided with internal screw thread, the outer surface of upper setting of liquid sample collector
There is external screw thread, liquid sample collector is threadedly coupled with liquid sample storage device, when liquid sample collector is revolved by screw thread
When going to least significant end, collector outlet is located in limiting slot and sharp portion punctures rubber film, collector outlet connecting tube
It is connected with storage chamber.
The interface arrangement is internally provided with the cylindrical cavity that upper surface is inclined-plane, and interface plugging device is arranged in circle
Cylindrical cavity lower end surface.
The top of the connecting pipe head matches with cylindrical cavity, and the upper surface of connecting pipe head is inclined-plane, connecting tube
Head is internally provided with truncated cone-shaped connecting cavity, and shape and the SPR detector sample-adding mouth-shaped of truncated cone-shaped connecting cavity match.
Reagent adsorption layer is connected in the middle part of the storage chamber.
The two sides of the storage device shell are also vertically provided with elastic extension item, the inner surface setting of elastic extension item
There is arc convex.
The present invention is sealed storage to liquid sample using multiple liquid sample collecting devices, and is arranged in storage chamber
There are reagent adsorption layer and filter device, makes liquid sample can be sufficiently with the detection reagent in reagent adsorption layer in reagent adsorption layer
The saliva sample of more clarification, bubble-free and impurity is precipitated in mixing, and the fluid sample for being mixed with detection reagent is finally filled through filtering
It sets in influent sample storage device；The present invention adopts the liquid sample equipped with liquid sample using liquid sample storage device
Storage is stored, conveying easy to carry, while logical as the transmission of SPR detector adding mouth and liquid sample storage device
Road.The U-shaped channel being arranged in liquid sample storage device, the injection rate of enough effectively control liquid samples, prevents liquid sample from existing
Injection rate is excessive when being injected by SPR detector adding mouth.The present invention is additionally provided with the push rod connecting with plug thread and rubber
Rubber plug can derive downwards push rod according to certain pressure according to actual use demand, extrude liquid sample using rubber stopper and store
Chamber avoids sample from polluting.When the present invention and SPR detector adding mouth are attached, if respectively will be in liquid sample storage device
Dry connecting pipe head accommodation groove alignment SPR detector adding mouth is simultaneously pressed, and the protruding portion of SPR detector adding mouth will pass through flexibility
The truncated cone-shaped connecting cavity of the inside of rubber layer and connecting pipe head setting fits closely, meanwhile, connecting pipe head will move upwards, and lead to
The inclined-plane or sharp portion bursting interface plugging device for crossing end flow into the testing liquid in interface arrangement corresponding
SPR detector adding mouth is detected.It effectively connect, deposits with SPR detector adding mouth for the ease of liquid sample storage device
The two sides of storage device shell are also vertically provided with elastic extension item, and the inner surface of elastic extension item is provided with arc convex.Elasticity
Liquid-like can be guaranteed by the frictional force and position-limiting action generated at elastic clamping and arc convex by extending item and arc convex
This storage device is reliably connected with SPR detector adding mouth.The present invention can be efficiently completed multiple fluid samples acquisition,
It mixing with detection reagent and is detected simultaneously using SPR detector, improves sample treatment efficiency, it can disposably will be more
A liquid template is directly injected into different SPR detector adding mouths and is detected.
Detailed description of the invention
Fig. 1 is the structural diagram of the present invention；
Fig. 2 is the structural schematic diagram of liquid sample collecting device in the present invention；
Fig. 3 is the structural schematic diagram of liquid sample storage device in the present invention.
Specific embodiment
The present invention is made with detailed description below in conjunction with drawings and examples:
As shown in Figure 1 to Figure 3, the Multi-channel liquid sample collection of the present invention suitable for hand-held SPR detector stores
Device, including liquid sample collecting device and liquid sample storage device；
The liquid sample collecting device is sampled for carrying out liquid sample to sample collector, and to obtained liquid
Sample is stored.Liquid sample collecting device includes multiple liquid sample collectors 1, and the upper end of liquid sample collector 1 is opened
Mouth is collector sample tap, and liquid sample collector 1 is internally provided with storage chamber 2, the lower end setting of liquid sample collector 1
There is the collector outlet 3 be connected with storage chamber 2, be provided with collector sample tap plugging device 5 on collector sample tap, acquires
Collector outlet plugging device 4 is provided on device outlet 3.Sample collector can be led liquid sample by collector sample tap
Enter in storage chamber 2, and be sealed collector sample tap using collector sample tap plugging device 5, cooperation collector goes out sample
Mouth plugging device 4, can effectively seal against storage liquid sample.
In the present embodiment, liquid sample collector 1 is tubular, and collector sample tap inner surface is provided with internal screw thread, is acquired
Device sample tap plugging device 5 is cylindrical sealing-plug, is provided on the outside of sealing-plug and matches with collector sample tap internal screw thread
External screw thread, sealing-plug is threadedly coupled with collector sample tap, can effectively improve sealing performance.The middle part of sealing-plug is along axial direction
It is provided with threaded hole, push rod 6 is provided in threaded hole, the lower part of push rod 6 is provided with thread segment 7, and the diameter of thread segment 7, which is greater than, to be pushed away
6 diameter of bar, the lower end of thread segment 7 are connected with the rubber stopper 8 to match with storage chamber 2, and storage chamber 2 is slidably connected with storage chamber 2.
Due to first is that needing to drive liquid sample to SPR detector adding mouth, depending merely on gravity realization in subsequent liquid detection process
The outflow of liquid sample is ineffective, second is that subsequent need to mix liquid sample with detection reagent, depends merely on shaking and passes through
Liquid sample collector 1 is also easy to produce a large amount of bubbles, and mixed effect is bad.Therefore, the present invention by rubber stopper 8 and push rod 6 effectively
It is combined with sealing-plug, is used convenient for follow-up work personnel.In view of portability of the invention, spiral shell can be passed through in sample phase
Line section 7 by entire push rod 6 be arranged in sealing-plug, when needing using push rod 6, push rod 6 can be rotated down, make thread segment 7 with
Sealing-plug is detached from, can be according to actual use demand according to a level pressure since 6 diameter of push rod of 7 top of thread segment is less than threaded hole
Power derives downwards push rod 6, and liquid sample is extruded storage chamber 2 using rubber stopper 8.In the present embodiment, the lower part of storage chamber 2 is to fall
Taper type 9 converges downwards under the effect of gravity convenient for liquid sample.
The liquid sample storage device, including storage device shell 10, the setting of 10 interior parallel of storage device shell
There are multiple acquisition device storage chambers 11, liquid sample collecting device is all made of removably and is correspondingly arranged in acquisition device storage
In chamber 11, each 11 lower end of acquisition device storage chamber is provided with collector outlet connecting tube 12, each collector outlet
Connecting tube 12 passes through the U-shaped channel 13 being arranged in inside storage device shell 10 and is connected with for connecting with SPR detector adding mouth
The interface arrangement 14 connect, corresponding collector outlet connecting tube, U-shaped channel 13 and interface arrangement conducting, each interface arrangement
14 lower ends are provided with connecting pipe head accommodation groove 23, and the two sides of connecting pipe head accommodation groove 23 offer sliding groove, connecting pipe head 24
It is slidably connected by the sliding shoe 25 that 24 two sides of connecting pipe head are arranged with connecting pipe head accommodation groove 23, is provided in connecting pipe head 24
The connecting cavity that SPR detector sample-adding mouth-shaped matches.
Liquid sample storage device is convenient for for storing to multiple liquid sample collectors 1 equipped with liquid sample
Conveying, while the transmission channel as SPR detector adding mouth and liquid sample storage device are carried, is convenient for and SPR detector
It is used cooperatively.In the present embodiment, outlet plugging device 4 and interface plugging device 15 are all made of rubber film.Collector goes out sample
Mouth connecting tube 12 is vertically arranged and end is provided with sharp portion, and acquisition device storage chamber bottom is additionally provided with and collector outlet
The shape of the limiting slot that outer diameter matches, limiting slot and collector outlet matches.11 inner surface of acquisition device storage chamber is set
It is equipped with internal screw thread, the outer surface of upper of liquid sample collector 1 is provided with external screw thread, liquid sample collector 1 and liquid sample
Storage device is threadedly coupled.When only be used only liquid sample storage device to equipped with liquid sample liquid sample collector 1 into
When row storage, it is only necessary to be connected the two by screw thread, without rotating liquid sample collector 1 to bottom.Work as needs
When SPR detector adding mouth being connected with liquid sample memory using liquid sample storage device, by liquid sample collector 1
When by screw thread rotation to least significant end, collector outlet 3 is positioned in limiting slot and sharp portion punctures rubber film, adopts at this time
Storage outlet connecting tube 12 and storage chamber 2 are connected.
Since there may be certain impurity in fluid sample, in order to improve Detection accuracy, the present invention is in storage chamber 2
It is inside provided with filter device 14, filter device 14 includes filter holder and the first filter screen, and filter holder includes and 2 phase of storage chamber
Matched mounting ring is provided with the first filter screen in mounting ring, and there are two supporting leg 18, the appearances of mounting ring for the setting of mounting ring lower part
Face is provided with rubber layer.Mounting ring and its rubber layer of outer surface setting, can effectively improve filter effect, prevent unfiltered
Liquid sample is flowed out from the gap between 2 inner wall of mounting ring and storage chamber.Meanwhile the design of supporting leg 18 may make the first filter screen energy
Access effective limit.In the present invention, filter device 14 is changeable type, can be replaced not according to liquid sample filtration needs
With the filter screen in filter hole aperture.
Interface arrangement is internally provided with the cylindrical cavity 21 that upper surface is inclined-plane, and interface plugging device 15 is arranged in cylinder
21 lower end surface of shape cavity.The top of connecting pipe head 24 matches with cylindrical cavity 21, and the upper surface of connecting pipe head 24 is inclined-plane,
Or it is provided with sharp portion, connecting pipe head 24 is internally provided with truncated cone-shaped connecting cavity 22, the shape and SPR of truncated cone-shaped connecting cavity 22
Detector sample-adding mouth-shaped matches.The settable flexible rubber layer of the inner surface of truncated cone-shaped connecting cavity 22, so that SPR detector adds
The protruding portion of sample mouth is fitted closely with truncated cone-shaped connecting cavity 22, guarantees certain airtightness, cooperates SPR detector internal negative pressure machine
Structure sucks liquid sample in the sample detection unit inside micro-fluidic chip.The setting of the lesser U-shaped channel 13 of internal diameter can
The effectively injection rate of control liquid sample prevents liquid sample injection rate when injecting by SPR detector adding mouth excessive.
In the present embodiment, the middle part of storage chamber 2 is connected with reagent adsorption layer 20, reagent adsorption layer 20 can be adsorbed in advance with
The corresponding detection reagent of fluid sample.The porous elastic material that sponge etc. has adsorption function can be used in reagent adsorption layer 20.When
After liquid sample collects storage chamber 2, liquid sample can be sufficiently with the detection reagent in reagent adsorption layer 20 in reagent adsorption layer
Mixing in 20, the fluid sample for being mixed with detection reagent flow out after rubber stopper 8 and filter device 14 squeeze, can be precipitated compared with
For the saliva sample of clarification, bubble-free and impurity, corresponding SPR detector adding mouth finally is flowed into through filter device 14, efficiently
The acquisition for completing multiple fluid samples and mixing with detection reagent, improve sample treatment efficiency, can disposably by
Multiple liquid templates are directly injected into different SPR detector adding mouths and are detected.
When the present invention is attached with SPR detector adding mouth, several in liquid sample storage device are connected respectively
Pipe joint accommodation groove 23 is directed at SPR detector adding mouth and presses, and the protruding portion of SPR detector adding mouth will pass through flexible rubber
The truncated cone-shaped connecting cavity 22 that the inside of layer and connecting pipe head 24 is arranged fits closely, meanwhile, connecting pipe head 24 will move upwards, and
By the inclined-plane or sharp portion bursting interface plugging device 15 of end, finally make the testing liquid inflow pair in interface arrangement 14
The SPR detector adding mouth answered is detected.Effectively connect for the ease of liquid sample storage device and SPR detector adding mouth
It connects, the two sides of storage device shell 10 are also vertically provided with elastic extension item 26, and the inner surface of elastic extension item is provided with arc
Protrusion 27.Elastic extension item 26 and arc convex 27 can pass through the frictional force and limit of generation at elastic clamping and arc convex 27
Position effect, guarantee liquid sample storage device are reliably connected with SPR detector adding mouth.
Claims (10)
1. a kind of Multi-channel liquid sample collection storage device suitable for hand-held SPR detector, it is characterised in that: including liquid
Body sample collecting device and liquid sample storage device；
The liquid sample collecting device, including multiple liquid sample collectors, the upper end opening of liquid sample collector be
Collector sample tap, liquid sample collector are internally provided with storage chamber, and the lower end of liquid sample collector is provided with and deposits
The collector outlet of storage chamber conducting, is provided with collector sample tap plugging device, collector outlet on collector sample tap
On be provided with collector outlet plugging device；
The liquid sample storage device, including storage device shell, storage device enclosure interior are provided with multiple acquisition dresses
Storage chamber is set, each liquid sample collecting device is all made of removably and is correspondingly arranged in each acquisition device storage chamber,
Each acquisition device storage chamber lower end is provided with collector outlet connecting tube, and each collector outlet connecting tube passes through
The U-shaped channel that storage device enclosure interior is arranged in is connected with interface arrangement for connecting with SPR detector adding mouth, corresponding
Collector outlet connecting tube, U-shaped channel and interface arrangement conducting, be provided with interface plugging device in interface arrangement；Each
It is provided with connecting pipe head accommodation groove below interface arrangement, the two sides of connecting pipe head accommodation groove offer sliding groove, connecting tube
The sliding shoe that head is arranged by connecting pipe head two sides is slidably connected with connecting pipe head accommodation groove, and SPR inspection is provided in connecting pipe head
Survey the connecting cavity that instrument sample-adding mouth-shaped matches.
2. the Multi-channel liquid sample collection storage device according to claim 1 suitable for hand-held SPR detector,
Be characterized in that: the liquid sample collector is tubular, and collector sample tap inner surface is provided with internal screw thread, collector sampling
Mouth plugging device is cylindrical sealing-plug, is provided with and the matched outer spiral shell of collector sample tap internal screw thread on the outside of sealing-plug
Line, sealing-plug are threadedly coupled with collector sample tap；The middle part of sealing-plug is axially disposed threaded hole, is provided in threaded hole
Push rod, the lower part of push rod are provided with thread segment, and the diameter of thread segment is greater than rod diameter, and the lower end of thread segment is connected with and stores
The rubber stopper that chamber matches, storage chamber are slidably connected with storage chamber.
3. the Multi-channel liquid sample collection storage device according to claim 2 suitable for hand-held SPR detector,
It is characterized in that: being provided with filter device in the storage chamber, filter device includes filter holder and the first filter screen, filtering branch
Frame includes the mounting ring to match with storage chamber, the first filter screen is provided in mounting ring, there are two branch for the setting of mounting ring lower part
The outer surface of leg, mounting ring is provided with rubber layer.
4. the Multi-channel liquid sample collection storage device according to claim 1 suitable for hand-held SPR detector,
Be characterized in that: the outlet plugging device and interface plugging device is all made of rubber film.
5. the Multi-channel liquid sample collection storage device according to claim 4 suitable for hand-held SPR detector,
Be characterized in that: the collector outlet connecting tube is vertically arranged and end is provided with sharp portion, acquisition device storage chamber bottom
Portion is additionally provided with the limiting slot to match with collector outlet outer diameter, and the shape of limiting slot and collector outlet matches.
6. the Multi-channel liquid sample collection storage device according to claim 5 suitable for hand-held SPR detector,
Be characterized in that: the acquisition device storage inner cavity surface is provided with internal screw thread, and the outer surface of upper of liquid sample collector is set
It is equipped with external screw thread, liquid sample collector is threadedly coupled with liquid sample storage device, when liquid sample collector passes through screw thread
When rotation to least significant end, collector outlet is located in limiting slot and sharp portion punctures rubber film, the connection of collector outlet
Pipe is connected with storage chamber.
7. the Multi-channel liquid sample collection storage device according to claim 1 suitable for hand-held SPR detector,
Be characterized in that: the interface arrangement is internally provided with the cylindrical cavity that upper surface is inclined-plane, and the setting of interface plugging device exists
Cylindrical cavity lower end surface.
8. the Multi-channel liquid sample collection storage device according to claim 7 suitable for hand-held SPR detector,
Be characterized in that: the top of the connecting pipe head matches with cylindrical cavity, and the upper surface of connecting pipe head is inclined-plane, connecting tube
Head is internally provided with truncated cone-shaped connecting cavity, and shape and the SPR detector sample-adding mouth-shaped of truncated cone-shaped connecting cavity match.
9. the Multi-channel liquid sample collection storage device according to claim 1 suitable for hand-held SPR detector,
It is characterized in that: being connected with reagent adsorption layer in the middle part of the storage chamber.
10. the Multi-channel liquid sample collection storage device according to claim 1 suitable for hand-held SPR detector,
It is characterized by: the two sides of the storage device shell are also vertically provided with elastic extension item, the inner surface of elastic extension item
It is provided with arc convex.
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