CN109984963B - Preparation method of pine pollen-turmeric antioxidant skin care product - Google Patents
Preparation method of pine pollen-turmeric antioxidant skin care product Download PDFInfo
- Publication number
- CN109984963B CN109984963B CN201910393771.4A CN201910393771A CN109984963B CN 109984963 B CN109984963 B CN 109984963B CN 201910393771 A CN201910393771 A CN 201910393771A CN 109984963 B CN109984963 B CN 109984963B
- Authority
- CN
- China
- Prior art keywords
- turmeric
- extract
- pine pollen
- skin care
- care product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9767—Pinaceae [Pine family], e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a preparation method of a pine pollen-turmeric antioxidant skin care product, which comprises the steps of preparing a pine pollen extract and a turmeric extract, and mixing the pine pollen extract and the turmeric extract to prepare the antioxidant skin care product. The invention has the beneficial effects that: the antioxidant skin care product prepared from natural extracts of pine pollen and turmeric does not contain harmful chemical additives, can effectively remove free radicals, reduce the ROS level, improve the activity of antioxidant enzyme, improve the skin elasticity and delay senility.
Description
Technical Field
The invention relates to the field of daily-use chemistry, in particular to a preparation method of a pine pollen-turmeric antioxidant skin care product.
Background
With the development of modern science, active oxygen free radical theory has been widely accepted in a plurality of theories of skin aging. In the normal physiological metabolism process of human body, a large amount of Reactive Oxygen Species (ROS) are generated under the influence of light, dust, radiation, ultraviolet rays, air pollution, fried food, pressure and the like. The human body is in a balanced state, and when the accumulation amount of ROS cannot be counteracted with the ability of the human body to remove free radicals, the balance is broken. The skin covers the whole body of people to isolate the inside of the human body from the external environment, is equivalent to a 'barrier' between the human body and the external environment, is directly exposed to the environment, is an important organ for protecting the human body and maintaining the stability and balance of the internal environment of the human body, more easily and more intuitively reflects the oxidative damage of the organism, and is expressed as skin aging or diseases such as photoaging, dermatitis, skin tumor and the like.
Because the antioxidant mechanism of the human body is not an independent system, but the result of the mutual coordination and combined action of various mechanisms of the human body. Therefore, the development and use of skin care products with antioxidant effect directly act on the body surface, can achieve the effect of delaying skin aging, and gradually become the main requirements of consumer groups. At present, an evaluation system for eliminating free radicals, reducing the level of ROS (reactive oxygen species), improving the antioxidant activity and other antioxidant effects is widely accepted and popularized, natural products from plants are sought, the use of chemical components is reduced, and antioxidant active components are obtained on the basis of health and safety, so that the evaluation system becomes a development hotspot for designing and developing anti-aging skin care products.
Disclosure of Invention
The invention provides a preparation method of a pine pollen-turmeric antioxidant skin care product, aiming at the problem that the existing antioxidant skin care product has non-natural chemical components.
The technical scheme for solving the technical problems is as follows: a preparation method of a pine pollen-turmeric antioxidant skin care product is characterized by comprising the following steps:
1) preparing a pine pollen extract: taking dried pollen of Pinus massoniana of Pinaceae, breaking cell wall, soaking in 95% ethanol solution for 12-15h for degreasing and decolorizing, centrifuging, taking precipitate, drying by blowing, adding distilled water with the mass being 12 times of that of the precipitate, stirring and leaching at 95 ℃ for 3h, centrifuging, taking precipitate, repeatedly leaching for 2 times, combining filtrates obtained by 3 times of leaching, decolorizing the filtrate by AB-8 macroporous resin, and concentrating under reduced pressure to 20% of the original volume to obtain pollen Pini extract solution;
2) preparing a turmeric extract: pulverizing dried Curcuma rhizome, sieving with 40 mesh sieve, collecting powder 500g, extracting with 8 times weight of 80% ethanol solution under heating and refluxing for three times (2 hr each time), filtering, mixing ethanol extractive solutions, concentrating under reduced pressure, and oven drying to obtain total curcumin compound Curcuma rhizome extract;
3) preparing a pine pollen-turmeric antioxidant skin care product: mixing the pine pollen extract solution obtained in the step 1) and the turmeric extract obtained in the step 2), adding the mixture into a solution of 1, 3-butanediol and purified water in a volume ratio of 3:2, and uniformly stirring to obtain the pine pollen-turmeric antioxidant skin care product.
Wherein the content of total flavonoids in the pine pollen extract obtained in the step 1) is not less than 0.18 mg/mL; the content of the total curcumin in the turmeric extract obtained in the step 2) is not lower than 0.20 mg/mL; the mass ratio of the pine pollen extract solution to the total curcumin compound extract in the step 3) is (3-8) to 1.
The pine pollen is fresh yellow or light yellow fine powder, and has sweet and mild taste and no toxicity. The history of the pine pollen used as both medicine and food is over a thousand years, the pine pollen is one of two kinds of pollen collected in ancient Chinese medical Lao-Shi, is the only pollen variety used as both food and medicine in the medical treasury of China, the record of the pine pollen in the first pharmacopoeia of China, Shennong Bencao Jing, is listed as the superior; the pharmacopoeia of the Tang Dynasty "Xin Xiu Ben Cao" also includes it; ming dynasty Li Shizhen is better called in Ben Cao gang mu: flos Pini, sweet and warm, has no toxicity, and can moisten heart and lung, invigorate qi, remove wind, stop bleeding, and also be used for brewing wine. As an ancient medicine source and a nutrient source, pine pollen is confirmed to be a new resource food by the ministry of health of China in recent years and listed as common food management, and is received in the 2005 edition of Chinese pharmacopoeia. The pine pollen contains all nutrient components and life active substances of pine plants, wherein the pine pollen contains a plurality of proteins, more than 20 amino acids (including 8 kinds of essential amino acids for human bodies), 15 vitamins, more than 30 mineral elements, 11% fat, nearly hundred kinds of enzymes and coenzymes, as well as nucleic acid, unsaturated fatty acid, lecithin, flavonoid, monosaccharide, polysaccharide, cellulose and the like, the total amount reaches more than 200 kinds, and the pine pollen is reasonably matched, can completely supplement and balance the nutrition required for the human bodies, has the effects of improving immunity, resisting aging, resisting fatigue, regulating organism metabolism, reducing blood fat, beautifying and the like, and is widely applied to the fields of health care products, medicines, cosmetics, feed additives and the like at home and abroad.
Turmeric (Curcuma longa L.) which is a curcumin plant of Zingiberaceae is a traditional botanical drug widely used in countries of Asia, and is collected in the Law edition of pharmacopoeia of the people's republic of China. Curcumin is derived from dried rhizome of Curcuma longa (Curcuma longaL) belonging to Curcuma of Zingiberaceae, and is one of effective components of Curcuma longa (Curcuma Longae). Has various good biological activities and pharmacological effects of resisting inflammation, resisting oxidation, etc. In traditional Chinese medicine, the traditional Chinese medicine has the advantages of obvious effect and low toxicity, and is more and more valued at home and abroad, and is used for dispelling wind, activating blood, stimulating the menstrual flow, relieving pain and the like. In modern research, aiming at the structural characteristics of plant polyphenol, a novel derivative or analogue is generated by means of synthesis, dehydrogenation, condensation and the like, and the novel derivative or analogue is widely applied to the field of daily chemicals by utilizing the oxidation resistance, free radical removal, anti-inflammation and antibacterial effects of the novel derivative or analogue, such as tyrosinase inhibitors, antioxidants and the like.
The total curcumin compound prepared in the step 2) mainly comprises three phenolic substances, which are respectively as follows: curcumin (curcumin, C)21H20O6Formula I), Demethoxycurcumin (Demethoxycurcumin, C)20H18O5Formula II) and Bisdemethoxycurcumin (Bisdeomethoxycurcumin, C)19H16O4Formula III).
The invention has the beneficial effects that: the antioxidant skin care product prepared from natural extracts of pine pollen and turmeric does not contain harmful chemical additives, can effectively remove free radicals, reduce the ROS level, improve the activity of antioxidant enzyme, improve the skin elasticity and delay senility.
Detailed Description
The present invention is described below with reference to examples, which are provided for illustration only and are not intended to limit the scope of the present invention.
Preparation work:
1) preparing a pine pollen extract: taking dry pollen of pinus massoniana of Pinaceae, breaking cell wall, soaking in 95% ethanol solution for 12-15h for degreasing and decoloring, centrifuging, taking precipitate, drying by blowing, adding distilled water with the mass being 12 times of that of the precipitate, stirring and leaching at 95 ℃ for 3h, centrifuging, taking precipitate, repeatedly leaching for 2 times, combining filtrates obtained by 3 times of leaching, decoloring the filtrates by AB-8 macroporous resin, concentrating under reduced pressure to 20% of the original volume to obtain a pollen pini extract solution, preparing a rutin standard solution, drawing a linear regression curve, determining the content of total flavonoids to be 0.25mg/mL by an ultraviolet-spectrophotometry, detecting the appearance, pH, the total number of bacterial colonies, mould, saccharomycetes, heat-resistant coliform group bacteria and other microbial indexes, and testing for later use after the total flavonoids are qualified;
2) preparing a turmeric extract: pulverizing dried Curcuma rhizome, sieving with 40 mesh sieve, collecting powder 500g, extracting with 8 times weight of 80% ethanol solution under heating and refluxing for three times, each for 2 hr, filtering, mixing ethanol extractive solutions, concentrating under reduced pressure, oven drying to obtain Curcuma rhizome extract as total curcumin compound, detecting appearance, pH, total bacterial count, mold and yeast, heat-resisting coliform group bacteria and other microorganism indexes by thin layer chromatography with total curcumin content of 0.28mg/mL, and checking.
Examples 1-3 are methods for preparing a pollen pini-turmeric antioxidant skin care product, respectively, the same operations being: mixing the pollen pini extract solution and the curcuma extract, adding the mixture into a solution of 1, 3-butanediol and purified water in a volume ratio of 3:2, and uniformly stirring, wherein the difference is that the proportions of the pollen pini extract solution and the curcuma extract in examples 1-3 are respectively 5:1, 8:1 and 3: 1.
DPPH clearance test
1. Test materials: absolute ethyl alcohol, analytically pure; 1, 1-diphenyl-2-trinitrophenylhydrazine (DPPH); dimethyl sulfoxide (DMSO);
2. the main test instrument: varioskan Flash enzyme-linked immunosorbent assay (ELISA); Milli-Q ultrapure water; an ultraviolet-visible spectrophotometer (TU-1810); a Brand pipette; a 96-hole enzyme label plate;
3. positive control drug: vc solution;
4. the test steps are as follows: accurately weighing 20mg of DPPH, and diluting to 250mL with absolute ethyl alcohol to obtain a solution with a concentration of 2X 10- 4A solution of DPPH in mol/L. The characteristic purple red chromogen 517nm absorption peak of DPPH solution is utilized, the decrease of A517 absorption after the test substance is added is measured by an enzyme-linked immunosorbent assay to show the scavenging capacity of the enzyme-linked immunosorbent assay (ELISA) instrument on organic free radicals, the test sample is diluted to different concentrations, 190 mu L DPPH and 10 mu L of sample are added into a 96-hole ELISA plate, and the total reaction volume is 200 mu L. The blank control group is 190 μ L DPPH +10 μ L DMSO, the tinfoil paper is wrapped well after being mixed uniformly and then is shaken in the dark for reaction for 30min, and the change of the absorbance value under the wavelength of 517nm is measured;
5. data processing: the inhibition rate of the antioxidant substance was calculated according to the following formula,
inhibition [ ([ 1- ([ DPPH. ] t/[ DPPH. ] t ═ 0) ] × 100%,
in the formula: [ DPPH. t ═ 0-initial concentration of 1, 1-diphenyl-2-trinitrophenylhydrazine free radical in the blank system,
[ DPPH. t-concentration of 1, 1-diphenyl-2-trinitrophenylhydrazine radical after addition of the drug to be tested.
The measured results are shown in table 1, the pine pollen extract and the curcumin extract have obvious antioxidant effect compared with a positive control Vc, when the mass ratio of the pine pollen extract to the curcumin extract is 3:1, the in-vitro antioxidant effect of the composition has obvious antioxidant effect compared with the single use of the pine pollen extract and the curcumin extract, and the in-vitro antioxidant effect of the composition has a synergistic effect.
TABLE 1 DPPH clearance results of examples 1-3
Clearance rate test of di-hydroxyl free radical
1. Test materials: phosphate buffer at pH 7.4, 0.2 mol/L; 5.0mmol/L of phenanthroline; dimethyl sulfoxide (DMSO); FeCl2；H2O2；
2. The main test instrument: varioskan Flash enzyme-linked immunosorbent assay (ELISA); Milli-Q ultrapure water; an ultraviolet-visible spectrophotometer (TU-1810); a Brand pipette; a 96-hole enzyme label plate; a constant temperature water bath device;
3. positive control drug: vc solution.
4. The test steps are as follows: taking 40 mu L of phosphate buffer solution with pH 7.4 and 0.2mol/L and 160 mu L of ultrapure water as blanks; taking 40 mu L of phosphate buffer solution, 30 mu L of phenanthroline and 30 mu L of FeCl2(7.5mmol/L) and 110. mu.L of ultrapure water as A were intact; taking 40 mu L of phosphate buffer solution, 30 mu L of phenanthroline and 20 mu L of FeCl290 μ L of ultrapure water and 20 μ L of Vc solution (0.1%) as a lesion; taking 40 mu L of phosphate buffer solution, 30 mu L of phenanthroline and 20 mu L of FeCl280 μ L of ultrapure water, 10 μ L of drugs with different concentrations and 20 μ L of Vc solution are used as A samples, the total volume of the reaction is 200 μ L, the above groups of samples are shaken up and then placed in a constant temperature water tank, the temperature is kept at 37 ℃ for 60min, the samples are placed at a wavelength of 510nm, and the measured absorbance (A) value is shown in Table 2.
TABLE 2 Absorbance (A) assay record
5. Data processing: the clearance of hydroxyl radicals was calculated according to the following formula:
hydroxyl radical clearance ═ x 100% (sample a-a damaged)/(a undamaged-a damaged) ];
the results are shown in table 3, and the pollen pini-curcuma longa antioxidant skin care product obtained in examples 1-3 has a significant effect of removing hydroxyl radicals.
TABLE 3 results of hydroxyl radical scavenging rates for examples 1-3
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (3)
1. A preparation method of a pine pollen-turmeric antioxidant skin care product is characterized by comprising the following steps:
1) preparing a pine pollen extract: taking dried pollen of Pinus massoniana of Pinaceae, breaking cell wall, soaking in 95% ethanol solution for 12-15h for degreasing and decolorizing, centrifuging, taking precipitate, drying by blowing, adding distilled water with the mass being 12 times of that of the precipitate, stirring and leaching at 95 ℃ for 3h, centrifuging, taking precipitate, repeatedly leaching for 2 times, combining filtrates obtained by 3 times of leaching, decolorizing the filtrate by AB-8 macroporous resin, and concentrating under reduced pressure to 20% of the original volume to obtain pollen Pini extract solution;
2) preparing a turmeric extract: pulverizing dried Curcuma rhizome, sieving with 40 mesh sieve, collecting powder 500g, extracting with 8 times weight of 80% ethanol solution under heating and refluxing for three times (2 hr each time), filtering, mixing ethanol extractive solutions, concentrating under reduced pressure, and oven drying to obtain total curcumin compound Curcuma rhizome extract;
3) preparing a pine pollen-turmeric antioxidant skin care product: mixing the pine pollen extract solution obtained in the step 1) and the turmeric extract obtained in the step 2), adding the mixture into a solution of 1, 3-butanediol and purified water in a volume ratio of 3:2, and uniformly stirring to obtain a pine pollen-turmeric antioxidant skin care product; the ratio of the pollen pini extract solution to the curcumin extract is 3:1, 5:1 or 8: 1.
2. The method for preparing the pine pollen-turmeric antioxidant skin care product according to claim 1, wherein the content of total flavonoids in the pine pollen extract obtained in step 1) is not less than 0.18 mg/mL.
3. The method for preparing the pine pollen-turmeric antioxidant skin care product according to claim 1, wherein the total curcumin content in the turmeric extract obtained in step 2) is not less than 0.20 mg/mL.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910393771.4A CN109984963B (en) | 2019-05-13 | 2019-05-13 | Preparation method of pine pollen-turmeric antioxidant skin care product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910393771.4A CN109984963B (en) | 2019-05-13 | 2019-05-13 | Preparation method of pine pollen-turmeric antioxidant skin care product |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109984963A CN109984963A (en) | 2019-07-09 |
| CN109984963B true CN109984963B (en) | 2022-02-11 |
Family
ID=67136416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910393771.4A Active CN109984963B (en) | 2019-05-13 | 2019-05-13 | Preparation method of pine pollen-turmeric antioxidant skin care product |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109984963B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113456559A (en) * | 2021-06-18 | 2021-10-01 | 南京中医药大学 | Lily pearlescent colorant with antioxidant effect and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6579543B1 (en) * | 2002-02-22 | 2003-06-17 | Jackie H. McClung | Composition for topical application to skin |
| CN102228666A (en) * | 2011-06-29 | 2011-11-02 | 烟台新时代健康产业有限公司 | Composition prepared from pine pollen and curcuma, preparation method thereof, and application of composition in preparing medicament for treating inflammatory bowel disease |
| CN104257575A (en) * | 2014-09-04 | 2015-01-07 | 杨珍 | Anti-wrinkle antioxidant vitamin-C skin-care powder |
| CN104739710A (en) * | 2015-02-25 | 2015-07-01 | 烟台新时代健康产业日化有限公司 | Skin regeneration compound and use thereof |
| CN106511217A (en) * | 2016-12-28 | 2017-03-22 | 广州市聚吉科绿色化学共性技术研究院有限公司 | Anti-aging composition and application thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4495406B2 (en) * | 2003-04-21 | 2010-07-07 | 株式会社武蔵野免疫研究所 | Sendangusa plant extract-containing composition |
| US8017162B2 (en) * | 2005-10-26 | 2011-09-13 | Oryza Oil & Fat Chemical Co., Ltd. | Anti-inflammatory agent |
| US8623335B2 (en) * | 2007-09-10 | 2014-01-07 | Tauna Ann Waddington | Scar and rosacea and other skin care treatment composition and method |
| CN105285977A (en) * | 2015-09-23 | 2016-02-03 | 洛阳华以生物工程有限公司 | Health-care product having efficacies of resisting ageing and improving immunity |
-
2019
- 2019-05-13 CN CN201910393771.4A patent/CN109984963B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6579543B1 (en) * | 2002-02-22 | 2003-06-17 | Jackie H. McClung | Composition for topical application to skin |
| CN102228666A (en) * | 2011-06-29 | 2011-11-02 | 烟台新时代健康产业有限公司 | Composition prepared from pine pollen and curcuma, preparation method thereof, and application of composition in preparing medicament for treating inflammatory bowel disease |
| CN104257575A (en) * | 2014-09-04 | 2015-01-07 | 杨珍 | Anti-wrinkle antioxidant vitamin-C skin-care powder |
| CN104739710A (en) * | 2015-02-25 | 2015-07-01 | 烟台新时代健康产业日化有限公司 | Skin regeneration compound and use thereof |
| CN106511217A (en) * | 2016-12-28 | 2017-03-22 | 广州市聚吉科绿色化学共性技术研究院有限公司 | Anti-aging composition and application thereof |
Non-Patent Citations (4)
| Title |
|---|
| Antioxidant capacity of fresh and dried rhizomes from four clones of turmeric (Curcuma longa L.) grown in vitro;M. Cousins等;《Industrial Crops and Products》;20070228;第25卷(第2期);第129-135页 * |
| 基于DPPH自由基清除能力的姜黄提取物抗氧化活性评价;王笑晴;《药物评价研究》;20111031;第34卷(第5期);第360页第1段,第362页第3节第2段,第361页第1.2.1节 * |
| 松花粉提取物护肤功效体外研究;潘松浩，等;《香料香精化妆品》;20181231(第6期);第29-32页 * |
| 松花粉黄酮提取物体外抗氧化作用的研究;回晶，等;《辽宁大学学报》;20140930;第41卷(第3期);第281页摘要 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109984963A (en) | 2019-07-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Yang et al. | Antioxidant and immunity activity of water extract and crude polysaccharide from Ficus carica L. fruit | |
| Rosidah et al. | Antioxidant potential of Gynura procumbens | |
| Dashora et al. | Antitumor activity of Dendrophthoe falcata against ehrlich ascites carcinoma in swiss albino mice | |
| Begum et al. | 44. Antioxidant, antimicrobial activity and phytochemical analysis of the seeds extract of Cucumis sativus Linn | |
| CN108042433B (en) | Whitening antioxidant plant composition, plant composition fermentation liquor, preparation method and application | |
| Naqash et al. | Anticoagulant, antiherpetic and antibacterial activities of sulphated polysaccharide from Indian medicinal plant Tridax procumbens L.(Asteraceae) | |
| Olakunle et al. | Toxicity, anti-lipid peroxidation, invitro and invivo evaluation of antioxidant activity of Annona muricata ethanol stem bark extract | |
| Jack et al. | Evaluation of phytochemical, antimicrobial and antioxidant capacities of Pennisetum purpureum (Schumach) extracts | |
| Chatterjee et al. | Antidiabetic and antioxidative activity of ethyl acetate fraction of hydromethanolic extract of seed of Eugenia jambolana Linn through in-vivo and in-vitro study and its chromatographic purification | |
| Isla et al. | Flower beverages of native medicinal plants from Argentina (Acacia caven, Geoffroea decorticans and Larrea divaricata) as antioxidant and anti-inflammatory | |
| KR102232572B1 (en) | Manufacturing method for cosmetic pomposition comprising centella asiatica extract | |
| Tisnadjaja et al. | Potency of cinnamomum burmannii as antioxidant and α glucosidase inhibitor and their relation to trans-cinamaldehyde and coumarin contents | |
| KR101178594B1 (en) | Cosmetic composition containing Polygonum multiflorum extracts, jujube extracts and Hibiscus manihot extracts for moisturizing skin | |
| Behrangi et al. | Comparison among cornelian cherry and Prunus cerasus according to phenolic content and antioxidant capacity by three various methods of extraction | |
| Nadilah et al. | Evaluation of DPPH free radical scavenging, α-glucosidase inhibitory, and antimicrobial activities of Aquilaria malaccensis leaf extracts | |
| Putri et al. | Administrations of Butterfly Pea Flower (Clitoria Ternatea L) Extract Reduce Oxidative Stress and Increase Body Weight of Male Wistar Rats with Diabetes. | |
| CN109984963B (en) | Preparation method of pine pollen-turmeric antioxidant skin care product | |
| Phansawan et al. | Antioxidant capacities of Pueraria mirifica, Stevia rebaudiana Bertoni, Curcuma longa Linn., Andrographis paniculata (Burm. f.) Nees. and Cassia alata Linn. for the development of dietary supplement | |
| Wang et al. | Polysaccharides from mulberry leaf in relation to their antioxidant activity and antibacterial ability | |
| Sarkar et al. | Evaluation of in vitro anti diabetic activity of two mangrove plant extracts: Heritiera fomes and Sonneratia apetala | |
| CN109078047B (en) | Preparation and application of effective part with tyrosinase inhibition effect in cortex mori | |
| Ghosh et al. | Comparison of different aqueous extraction methods for optimum extraction of polyphenols and in-vitro anti-oxidant activity from pomegranate peel | |
| Ojha et al. | Aloe vera gel: A potent nutraceutical | |
| KR101480695B1 (en) | Cosmetic composition containing Scutellaria baicalensis extract using processing of herbal medicine | |
| Luong et al. | Antioxidant and Blood Sugar-Stabilizing Activities of Extracts from Three Coloured Rice Varieties in Streptozotocin-Induced Diabetic Mice. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |