CN109982721A - 靶向并结合恶性肿瘤而非良性肿瘤的可检测分子 - Google Patents

靶向并结合恶性肿瘤而非良性肿瘤的可检测分子 Download PDF

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Publication number
CN109982721A
CN109982721A CN201780071462.4A CN201780071462A CN109982721A CN 109982721 A CN109982721 A CN 109982721A CN 201780071462 A CN201780071462 A CN 201780071462A CN 109982721 A CN109982721 A CN 109982721A
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China
Prior art keywords
present
malignant
bind
cells
targets
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Pending
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CN201780071462.4A
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English (en)
Chinese (zh)
Inventor
史蒂文·D·延森
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Cao Group Inc
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Cao Group Inc
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Publication of CN109982721A publication Critical patent/CN109982721A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7023—(Hyper)proliferation
    • G01N2800/7028—Cancer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
CN201780071462.4A 2016-10-26 2017-10-25 靶向并结合恶性肿瘤而非良性肿瘤的可检测分子 Pending CN109982721A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662412948P 2016-10-26 2016-10-26
US62/412,948 2016-10-26
PCT/US2017/058276 WO2018081262A1 (en) 2016-10-26 2017-10-25 Detectable molecules that target and bind to malignant tumors and not benign tumors

Publications (1)

Publication Number Publication Date
CN109982721A true CN109982721A (zh) 2019-07-05

Family

ID=62025452

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780071462.4A Pending CN109982721A (zh) 2016-10-26 2017-10-25 靶向并结合恶性肿瘤而非良性肿瘤的可检测分子

Country Status (4)

Country Link
US (1) US20190255195A1 (https=)
JP (1) JP2019536015A (https=)
CN (1) CN109982721A (https=)
WO (1) WO2018081262A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040047804A1 (en) * 1998-10-29 2004-03-11 The General Hospital Corporation, A Massachusetts Corporation Enhanced radiation therapy
CN102372771A (zh) * 2010-08-26 2012-03-14 杨静雯 一种肿瘤靶向分子及其应用
CN104892820A (zh) * 2015-05-11 2015-09-09 厦门大学 一种受体类分子靶向显像剂及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9678059B2 (en) * 2010-05-23 2017-06-13 Technion Research & Development Foundation Ltd. Detection, staging and grading of benign and malignant tumors
WO2014074805A1 (en) * 2012-11-08 2014-05-15 Whitehead Institute For Biomedical Research Selective targeting of cancer stem cells

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040047804A1 (en) * 1998-10-29 2004-03-11 The General Hospital Corporation, A Massachusetts Corporation Enhanced radiation therapy
CN102372771A (zh) * 2010-08-26 2012-03-14 杨静雯 一种肿瘤靶向分子及其应用
CN104892820A (zh) * 2015-05-11 2015-09-09 厦门大学 一种受体类分子靶向显像剂及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FREDERICK E. DOMANN等: "Constitutive AP-1 DNA Binding and Transactivating Ability of Malignant but Not Benign Mouse Epidermal Cells", 《MOLECULAR CARCINOGENESIS》 *
JARED J. BARROTT等: "Tethered Hsp90 Inhibitors Carrying Optical or Radioiodinated Probes Reveal Selective Internalization of Ectopic Hsp90 in Malignant Breast Tumor Cells", 《CHEM BIOL.》 *

Also Published As

Publication number Publication date
WO2018081262A1 (en) 2018-05-03
US20190255195A1 (en) 2019-08-22
JP2019536015A (ja) 2019-12-12

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Application publication date: 20190705