CN109975102A - The device of suspended solid in a kind of separation fluid - Google Patents
The device of suspended solid in a kind of separation fluid Download PDFInfo
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- CN109975102A CN109975102A CN201910289839.4A CN201910289839A CN109975102A CN 109975102 A CN109975102 A CN 109975102A CN 201910289839 A CN201910289839 A CN 201910289839A CN 109975102 A CN109975102 A CN 109975102A
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- flow channel
- chamber
- runner
- separation
- separation chamber
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- 238000000926 separation method Methods 0.000 title claims abstract description 88
- 239000012530 fluid Substances 0.000 title claims abstract description 22
- 239000007787 solid Substances 0.000 title claims abstract description 20
- 230000000694 effects Effects 0.000 abstract description 34
- 238000001514 detection method Methods 0.000 abstract description 3
- 210000002381 plasma Anatomy 0.000 description 40
- 210000004369 blood Anatomy 0.000 description 29
- 239000008280 blood Substances 0.000 description 29
- 230000006835 compression Effects 0.000 description 5
- 238000007906 compression Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000010276 construction Methods 0.000 description 4
- 230000010148 water-pollination Effects 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 238000009832 plasma treatment Methods 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000009194 climbing Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a kind of devices of suspended solid in separation fluid, are related to detection device technical field；It includes the inlet chamber (1) for being sequentially connected conducting, first runner (2), separation chamber and second flow channel, the second flow channel includes time sluice way (3-1), bend (3-2) and the aerial drainage runner (3-3) for being sequentially connected conducting, described time sluice way (3-1) connect conducting with separation chamber, and the outlet of the bend (3-2), the entrance and aerial drainage runner (3-3) that return sluice way (3-1) is radially outward sequentially distributed along rotary shaft；It realizes the solid to suspend in separation fluid and transfers out the fluid after separation, the module is small in size, and work efficiency is high, and effect is good by inlet chamber, first runner, separation chamber and second flow channel etc..
Description
Technical field
The present invention relates to a kind of devices of suspended solid in detection device technical field more particularly to separation fluid.
Background technique
Currently, the equipment for separating the solid to suspend in fluid in detection process, mostly bulky, realize that efficiency is lower,
Effect is poor.
For example, by blood plasma and the haemocyte equipment that separates and transfer out blood plasma in blood, it is mostly bulky, realize effect
Rate is lower, and effect is poor.
Rotate monitor station revolving speed explanation:
High revolving speed is > 50Hz；
Middle revolving speed is 15Hz~50Hz；
The slow-speed of revolution is < 15Hz；
Unit Hz be circle/second.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of devices of suspended solid in separation fluid, pass through entrance
Room, first runner, separation chamber and second flow channel etc. realize the solid to suspend in separation fluid and transfer out the stream after separation
Body, the module is small in size, and work efficiency is high, and effect is good.
In order to solve the above technical problems, the technical solution used in the present invention is: include be sequentially connected conducting inlet chamber,
First runner, separation chamber and second flow channel, the second flow channel include time sluice way, bend and the aerial drainage stream for being sequentially connected conducting
Road, described time sluice way connect conducting, the outlet edge rotation of the bend, the entrance for returning sluice way and aerial drainage runner with separation chamber
Axis is radially outward sequentially distributed.
A further technical solution lies in: it further include the third flow channel that conducting is connect with the separation chamber, the third stream
Road and the junction of separation chamber are third flow channel connector, and the junction of described time sluice way and separation chamber is that second flow channel connects
Mouthful, the third flow channel, third flow channel connector and second flow channel connector are radially outward sequentially distributed along rotary shaft.
A further technical solution lies in: the first runner is the runner for the flow resistance that flow resistance is greater than second flow channel.
A further technical solution lies in: the third flow channel is the runner for the flow resistance that flow resistance is greater than second flow channel.
A further technical solution lies in: described time sluice way is capillary flow path.
A further technical solution lies in: the third flow channel connectors to be located at the separation along rotary shaft radially-inwardly side
On room.
A further technical solution lies in: the second flow channel connector is located at the middle part of separation chamber, the third flow channel
Connector is located at the middle part of separation chamber.
A further technical solution lies in: the inlet chamber and separation chamber to be radially outward sequentially distributed along rotary shaft, described
Bend and separation chamber are radially outward sequentially distributed along rotary shaft.
A further technical solution lies in: the separation chamber includes that conducting is radially outward sequentially distributed and connected along rotary shaft
Discharge chambe and mud chamber, the first runner be connected between inlet chamber and mud chamber.
A further technical solution lies in: the separation chamber further includes retract chamber, the retract chamber be connected to discharge chambe with
Between mud chamber, described time sluice way connect conducting with retract chamber.
The beneficial effects of adopting the technical scheme are that
First, inlet chamber, first runner, separation chamber and second flow channel including being sequentially connected conducting, the second flow channel includes
Be sequentially connected conducting returns sluice way, bend and aerial drainage runner, and described time sluice way connect conducting with separation chamber, the bend,
The outlet for returning the entrance and aerial drainage runner of sluice way is radially outward sequentially distributed along rotary shaft.The technical solution realizes separation
The solid that suspends in fluid simultaneously transfers out the fluid after separation, and the module is small in size, and work efficiency is high, and effect is good.
Second, it further include the third flow channel that conducting is connect with the separation chamber, the connection of the third flow channel and separation chamber
Place is third flow channel connector, and the junction of described time sluice way and separation chamber is second flow channel connector, the third flow channel,
Third flow channel connector and second flow channel connector are radially outward sequentially distributed along rotary shaft.The technical solution, more reasonable structure,
Module volume is smaller, and working efficiency is higher, and effect is more preferable.
Third, the first runner are the runner for the flow resistance that flow resistance is greater than second flow channel.The technical solution, structure are more closed
Reason, module-occupying space is smaller, and working efficiency is higher, and effect is more preferable.
4th, the third flow channel is the runner for the flow resistance that flow resistance is greater than second flow channel.The technical solution, structure are more closed
Reason, module-occupying space is smaller, and working efficiency is higher, and effect is more preferable.
5th, described time sluice way is capillary flow path.The technical solution, more reasonable structure, working efficiency is higher, effect
More preferably.
6th, the third flow channel connector is located in the rotary shaft radially-inwardly separation chamber of side.The technical solution,
More reasonable structure, module volume is smaller, and working efficiency is higher, and effect is more preferable.
7th, the second flow channel connector is located at the middle part of separation chamber, and the third flow channel connector is located at separation chamber
Middle part.The technical solution, more reasonable structure, working efficiency is higher, and effect is more preferable.
8th, the inlet chamber and separation chamber are radially outward sequentially distributed along rotary shaft, and the bend and separation chamber are along rotation
Shaft is radially outward sequentially distributed.The technical solution, more reasonable structure, stability is more preferable, and working efficiency is higher, and effect is more preferable.
9th, the separation chamber includes the discharge chambe and precipitating that conducting is radially outward sequentially distributed and connected along rotary shaft
Room, the first runner are connected between inlet chamber and mud chamber.The technical solution, more reasonable structure, stability is more preferable, work
More efficient, effect is more preferable.
Tenth, the separation chamber further includes retract chamber, and the retract chamber is connected between discharge chambe and mud chamber, and described time
Sluice way connect conducting with retract chamber.The technical solution, more reasonable structure, stability is more preferable, and working efficiency is higher, and effect is more
It is good.
It is detailed in specific embodiment part description.
Detailed description of the invention
Fig. 1 is the structure chart of the embodiment of the present invention 1；
Fig. 2 is the first working state figure of the embodiment of the present invention 1；
Fig. 3 is the second working state figure of the embodiment of the present invention 1；
Fig. 4 is the third working state figure of the embodiment of the present invention 1；
Fig. 5 is the 4th working state figure of the embodiment of the present invention 1；
Fig. 6 is the structure chart of the embodiment of the present invention 2；
Fig. 7 is the structure chart of the embodiment of the present invention 3；
Fig. 8 is the structure chart of the embodiment of the present invention 4；
Fig. 9 is the structure chart of the embodiment of the present invention 5；
Figure 10 is the structure chart of the embodiment of the present invention 6.
Wherein: 1 inlet chamber, 2 first runners, 3-1 return sluice way, 3-2 bend, 3-3 aerial drainage runner, 3-4 second flow channel and connect
Interface, 4-1 third flow channel, 4-2 retract chamber side third flow channel connector, 4-3 discharge chambe side third flow channel connector, 5-1 compression
Room, the mud chamber 5-2,5-3 retract chamber, 6 blood, 6-1 blood plasma, 6-2 haemocyte.
Specific embodiment
Below in conjunction with the attached drawing in the embodiment of the present application, technical solutions in the embodiments of the present application carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of embodiments of the present application, instead of all the embodiments.Below
Description only actually at least one exemplary embodiment be it is illustrative, never as to the application and its application or making
Any restrictions.Based on the embodiment in the application, those of ordinary skill in the art are not making creative work premise
Under every other embodiment obtained, shall fall in the protection scope of this application.
Many details are explained in the following description in order to fully understand the application, but the application can be with
Implemented using other than the one described here other way, those skilled in the art can be without prejudice to the application intension
In the case of do similar popularization, therefore the application is not limited by the specific embodiments disclosed below.
It should be noted that term used herein above is merely to describe specific embodiment, and be not intended to restricted root
According to the illustrative embodiments of the application.As used herein, unless the context clearly indicates otherwise, otherwise singular
Also it is intended to include plural form, additionally, it should be understood that, when in the present specification using term "comprising" and/or " packet
Include " when, indicate existing characteristics, step, operation, device, component and/or their combination.
Unless specifically stated otherwise, positioned opposite, the digital table of the component and step that otherwise illustrate in these embodiments
Up to the unlimited scope of the present application processed of formula and numerical value.Simultaneously, it should be appreciated that for ease of description, each portion shown in attached drawing
The size divided not is to draw according to actual proportionate relationship.For technology, side known to person of ordinary skill in the relevant
Method and equipment may be not discussed in detail, but in the appropriate case, and the technology, method and apparatus should be considered as authorizing explanation
A part of book.In shown here and discussion all examples, any occurrence should be construed as merely illustratively, and
Not by way of limitation.Therefore, the other examples of exemplary embodiment can have different values.It should also be noted that similar label
Similar terms are indicated in following attached drawing with letter, therefore, once it is defined in a certain Xiang Yi attached drawing, then subsequent attached
It does not need that it is further discussed in figure.
In the description of the present application, it is to be understood that the noun of locality such as " front, rear, top, and bottom, left and right ", " laterally, vertical,
Vertically, orientation or positional relationship indicated by level " and " top, bottom " etc. is normally based on orientation or position shown in the drawings and closes
System is merely for convenience of description the application and simplifies description, and in the absence of explanation to the contrary, these nouns of locality do not indicate that
It must have a particular orientation or be constructed and operated in a specific orientation with the device or element for implying signified, therefore cannot manage
Solution is the limitation to the application protection scope；The noun of locality " inside and outside " refers to inside and outside the profile relative to each component itself.
For ease of description, spatially relative term can be used herein, as " ... on ", " ... top ",
" ... upper surface ", " above " etc., for describing such as a device shown in the figure or feature and other devices or spy
The spatial relation of sign.It should be understood that spatially relative term is intended to comprising the orientation in addition to device described in figure
Except different direction in use or operation.For example, being described as if the device in attached drawing is squeezed " in other devices
It will be positioned as " under other devices or construction after part or construction top " or the device of " on other devices or construction "
Side " or " under other devices or construction ".Thus, exemplary term " ... top " may include " ... top " and
" in ... lower section " two kinds of orientation.The device can also be positioned with other different modes and (is rotated by 90 ° or in other orientation), and
And respective explanations are made to the opposite description in space used herein above.
In addition, it should be noted that, limiting components using the words such as " first ", " second ", it is only for be convenient for
Corresponding components are distinguished, do not have Stated otherwise such as, there is no particular meanings for above-mentioned word, therefore should not be understood as to this
Apply for the limitation of protection scope.
Embodiment 1:
As Figure 1-Figure 5, the invention discloses a kind of devices of suspended solid in separation fluid, including being sequentially connected conducting
Inlet chamber 1, first runner 2, separation chamber and second flow channel, the separation chamber include radially outward being sequentially distributed and connecting along rotary shaft
The discharge chambe 5-1, retract chamber 5-3 and mud chamber 5-2 of conducting are met, the second flow channel includes time sluice way for being sequentially connected conducting
3-1, bend 3-2 and aerial drainage runner 3-3, the first runner 2 are connected between inlet chamber 1 and mud chamber 5-2, described time drainage
Road 3-1 connect conducting with retract chamber 5-3, and the junction for returning sluice way 3-1 and retract chamber 5-3 is second flow channel connector 3-4, institute
The outlet of inlet chamber 1, bend 3-2, discharge chambe 5-1, second flow channel connector 3-4 and aerial drainage runner 3-3 are stated along rotary shaft radial direction
It is sequentially distributed outward.
The entrance of described time sluice way 3-1 is second flow channel connector 3-4.
Operation instruction:
As shown in Fig. 2, the first step, instills blood 6 in inlet chamber 1, this module is placed on rotation monitor station, operation rotation
Monitor station middling speed rotation clockwise.
As shown in figure 3, second step, under the influence of centrifugal force, the blood 6 in inlet chamber 1 are introduced into mud chamber 5-2, when
After the liquid level of blood 6 is higher than second flow channel connector 3-4, the blood 6 for continuing to pour in starts to compressible Jie in discharge chambe 5-1
Matter is compressed.
Operation rotates monitor station high speed rotation clockwise, and 6 almost all of blood in inlet chamber 1 is introduced into separation chamber.
As shown in figure 4, third step, keeps rotation monitor station high speed rotation clockwise, effect of the haemocyte 6-2 in centrifugal force
Under be deposited in mud chamber 5-2, and blood plasma 6-1 be located at first runner 2, discharge chambe 5-1, retract chamber 5-3 and return sluice way 3-1
Interior, the compressible medium in discharge chambe 5-1 is compressed at this time；It is returned in the liquid level position in sluice way 3-1 and first runner 2 at this time
Liquid level position it is concordant and more radial more inner than the liquid level position in discharge chambe 5-1.
As shown in figure 5, the 4th step, operation rotates monitor station low speed rotation clockwise, the compressible medium in discharge chambe 5-1
Expansion, separates indoor blood plasma 6-1 at this time and is transported to first runner 2 and second flow channel and crosses bend 3-2, next exist
Under the action of centrifugal force, due to siphonic effect, separates indoor blood plasma 6-1 and transferred out via aerial drainage runner 3-3.
The inventive concept of embodiment 1: by being sequentially connected the inlet chamber 1 of conducting, first runner 2, separation chamber, returning sluice way
3-1, bend 3-2 and aerial drainage runner 3-3, the bend 3-2 and separation chamber are radially outward sequentially distributed along rotary shaft, return sluice way
The outlet of the entrance and aerial drainage runner 3-3 of 3-1 is radially outward sequentially distributed along rotary shaft, solves blood plasma in blood and blood is thin
The technical issues of born of the same parents separate and transfer out blood plasma, this module is small in size, and work efficiency is high, and effect is good.
Embodiment 2:
As shown in fig. 6, embodiment 2 is similar to Example 1, the difference is that, the bend 3-2, inlet chamber 1 and discharge chambe 5-
1 is radially outward sequentially distributed along rotary shaft, and the first runner 2 is the runner for the flow resistance that flow resistance is greater than second flow channel.
Inlet chamber 1, first runner 2, separation chamber and second flow channel including being sequentially connected conducting, the separation chamber includes edge
Rotary shaft is radially outward sequentially distributed and connects the discharge chambe 5-1, retract chamber 5-3 and mud chamber 5-2 of conducting, the second flow channel
Time sluice way 3-1, bend 3-2 and aerial drainage runner 3-3, the first runner 2 including being sequentially connected conducting are connected to inlet chamber 1
Between mud chamber 5-2, described time sluice way 3-1 connect conducting with retract chamber 5-3, goes back to the company of sluice way 3-1 and retract chamber 5-3
Meeting place is second flow channel connector 3-4, the bend 3-2, inlet chamber 1, discharge chambe 5-1, second flow channel connector 3-4 and aerial drainage
The outlet of runner 3-3 is radially outward sequentially distributed along rotary shaft.
The entrance of described time sluice way 3-1 is second flow channel connector 3-4.
Operation instruction:
As shown in fig. 6, embodiment 2 is similar to Example 1, the difference is that,
4th step, the compressible medium expansion in discharge chambe 5-1, separates indoor blood plasma 6-1 at this time and is transported to first runner 2
And second flow channel, since the flow resistance of first runner 2 is greater than the flow resistance of second flow channel, blood plasma 6-1 climbs relatively slowly along first runner 2,
Blood plasma 6-1 will not pour in inlet chamber 1, and blood plasma 6-1 can only cross bend 3-2, next under the influence of centrifugal force, due to rainbow
Effect is inhaled, indoor blood plasma 6-1 is separated and is transferred out via aerial drainage runner 3-3.Due to the bend 3-2, inlet chamber 1 and compression
Room 5-1 is radially outward sequentially distributed along rotary shaft, which makes the layout of this module more compact, saves the sky of occupancy
Between.
The inventive concept of embodiment 2: by being sequentially connected the inlet chamber 1 of conducting, first runner 2, separation chamber, returning sluice way
3-1, bend 3-2 and aerial drainage runner 3-3, the bend 3-2 and separation chamber are radially outward sequentially distributed along rotary shaft, return sluice way
The outlet of the entrance and aerial drainage runner 3-3 of 3-1 is radially outward sequentially distributed along rotary shaft, solves blood plasma in blood and blood is thin
The technical issues of born of the same parents separate and transfer out blood plasma, this module volume is smaller, and working efficiency is higher, and effect is more preferable.
As shown in fig. 6, when bend 3-2, inlet chamber 1 and discharge chambe 5-1 are radially outward sequentially distributed along rotary shaft,
It uses first runner 2 to be greater than the runner of the flow resistance of second flow channel for flow resistance, solves the technical issues of reducing module volume, this mould
The layout of block is more compact, has saved the space occupied.
Since bend 3-2, inlet chamber 1 and discharge chambe 5-1 are radially outward sequentially distributed along rotary shaft, so that the cloth of this module
Office is more compact, saves the space occupied.
When bend 3-2, inlet chamber 1 and discharge chambe 5-1 are radially outward sequentially distributed along rotary shaft, due to using
First runner 2 is the runner for the flow resistance that flow resistance is greater than second flow channel, solves blood plasma 6-1 and asks from the technology that second flow channel exports
Topic.
Since the flow resistance of first runner 2 is greater than the flow resistance of second flow channel, when separation chamber transfers out blood plasma, first runner 2
It is like to be tightened mouth, blood plasma 6-1 can hardly be climbed along first runner 2, separated indoor compressed media and suppressed the strength entirely
Power blood plasma 6-1 is exported from second flow channel, delivery efficiency further increases while outputing more blood plasma 6-1.
Embodiment 3:
As shown in fig. 7, embodiment 3 is similar to Example 1, the difference is that, it further include third flow channel 4-1, the third stream
One end of road 4-1 connect conducting with retract chamber 5-3, and the other end of third flow channel 4-1 is connected to gas vent, third flow channel 4-1 with
The junction of retract chamber 5-3 is third flow channel connector, which is retract chamber side third flow channel connector 4-
Gas vent, bend 3-2, retract chamber side third flow channel connector 4-2 and the second flow channel connector 3- of 2, the third flow channel 4-1
4 are radially outward sequentially distributed along rotary shaft.
Operation instruction:
Embodiment 3 is similar to Example 1, the difference is that second step, when the liquid level of blood 6 is higher than retract chamber side third flow channel
After connector 4-2, the blood 6 for continuing to pour in starts to compress the compressible medium in discharge chambe 5-1.It is advantageous in that implementation
Example 3 is fewer than embodiment 1 to have compressed compressible medium in discharge chambe 5-1, in situation similar in separation chamber volume, almost without subtracting
Few blood 6 reduces compression time, further improves working efficiency, and also almost without reduction in the volume of separation chamber
The volume of the blood plasma 6-1 exported from second flow channel.When handling the blood 6 of same volume, hence it is evident that reduce discharge chambe 5-1 occupancy
Space.For example, the blood of 30uL 6 is equally pressed into discharge chambe 5-1, compressed medium amount is bigger, the discharge chambe 5-1 needed
Volume is bigger, because compressed medium amount is less susceptible to compress more greatly.
The inventive concept of embodiment 3: by being sequentially connected the inlet chamber 1 of conducting, first runner 2, separation chamber, returning sluice way
3-1, bend 3-2 and aerial drainage runner 3-3, the bend 3-2 and separation chamber are radially outward sequentially distributed along rotary shaft, return sluice way
The outlet of the entrance and aerial drainage runner 3-3 of 3-1 is radially outward sequentially distributed along rotary shaft, solves blood plasma in blood and blood is thin
The technical issues of born of the same parents separate and transfer out blood plasma, this module is small in size, and work efficiency is high, and effect is good.
By third flow channel 4-1, third flow channel connector and second flow channel connector 3-4 along rotary shaft radially outward successively
Distribution, solves the technical issues of further increasing working efficiency, solves the technical issues of further decreasing module volume.
Embodiment 4:
As shown in figure 8, embodiment 4 is similar to Example 2, the difference is that, it further include third flow channel 4-1, the third stream
One end of road 4-1 connect conducting with retract chamber 5-3, and the other end of third flow channel 4-1 is connected to gas vent, third flow channel 4-1 with
The junction of retract chamber 5-3 is third flow channel connector, which is retract chamber side third flow channel connector 4-
2, the bend 3-2, the gas vent of third flow channel 4-1, retract chamber side third flow channel connector 4-2 and second flow channel connector 3-
4 are radially outward sequentially distributed along rotary shaft.The third flow channel 4-1 is the runner for the flow resistance that flow resistance is greater than second flow channel.
Operation instruction:
Embodiment 4 is similar to Example 2, the difference is that the 4th step, compressible medium expansion in discharge chambe 5-1, at this time
It separates indoor blood plasma 6-1 and is transported to first runner 2, second flow channel and third flow channel 4-1, due to first runner 2 and third
The flow resistance of runner 4-1 is all larger than the flow resistance of second flow channel, and blood plasma 6-1 can only cross bend 3-2, next in the effect of centrifugal force
Under, due to siphonic effect, separates indoor blood plasma 6-1 and transferred out via aerial drainage runner 3-3.
Embodiment 5:
As shown in figure 9, embodiment 5 is similar to Example 1, the difference is that, it further include third flow channel 4-1, the third stream
One end of road 4-1 connect conducting with discharge chambe 5-1, and the other end of third flow channel 4-1 is connected to gas vent, third flow channel 4-1 with
The junction of discharge chambe 5-1 is third flow channel connector, which is discharge chambe side third flow channel connector 4-
3, the discharge chambe side third flow channel connector 4-3 are located at discharge chambe 5-1 along the radially inward side of rotary shaft, the bend 3-
2, the gas vent of third flow channel 4-1, discharge chambe side third flow channel connector 4-3 and second flow channel connector 3-4 are along the rotation diameter of axle
To being sequentially distributed outward.Described time sluice way 3-1 is capillary flow path, itself is hydrophilic capillary for blood plasma 6-1
Pipe runner or the capillary flow path for doing hydrophily processing.
Operation instruction:
As shown in figure 9, embodiment 5 is similar to Example 1, the difference is that, second step, the blood 6 poured in is not to discharge chambe
Compressible medium in 5-1 is compressed, and blood 6 is by the medium in discharge chambe 5-1 via the row of exhausting-gas hole of third flow channel 4-1
Out.Embodiment 5 is advantageous in that compared with Example 1 without compressing the medium in discharge chambe 5-1, in the identical feelings of separation chamber volume
Under condition, blood 6 is not reduced in the volume of separation chamber, eliminates compression time, further improves working efficiency, and is several yet
Without reducing the volume of the blood plasma 6-1 exported from second flow channel.Meanwhile in the case where handling same volume blood 6, this skill
Art scheme further saves space.
4th step, operation rotation monitor station low speed rotation clockwise, under the action of the capillary force of capillary flow path, capillary
Along returning sluice way 3-1 climbing and crossing bend 3-2, next blood plasma 6-1 in pipe runner overcomes the centrifugal force of its own
Under the influence of centrifugal force, it due to siphonic effect, separates indoor blood plasma 6-1 and is transferred out via aerial drainage runner 3-3.
The inventive concept of embodiment 5: by being sequentially connected the inlet chamber 1 of conducting, first runner 2, separation chamber, returning sluice way
3-1, bend 3-2 and aerial drainage runner 3-3, the bend 3-2 and separation chamber are radially outward sequentially distributed along rotary shaft, return sluice way
The outlet of the entrance and aerial drainage runner 3-3 of 3-1 is radially outward sequentially distributed along rotary shaft, solves blood plasma in blood and blood is thin
The technical issues of born of the same parents separate.
The third flow channel connector is located in the rotary shaft radially-inwardly separation chamber of side, eliminates compression separation chamber
The time of interior medium, further improve working efficiency.
Described time sluice way 3-1 is capillary flow path, solves the technical issues of transferring out blood plasma.
Being located in the rotary shaft radially-inwardly separation chamber of side and return sluice way 3-1 in third flow channel connector is hair
Under the collective effect of capillary flow passage, solve the technical issues of blood plasma and haemocyte in blood separate and transfers out blood plasma, into
One step improves work efficiency, this module is small in size, and effect is good.
Embodiment 6:
As shown in Figure 10, embodiment 6 is similar to Example 1, the difference is that, the separation chamber and bend 3-2 are along rotary shaft
It is radially outward sequentially distributed, i.e., the outlet of described discharge chambe 5-1, bend 3-2, second flow channel connector 3-4 and aerial drainage runner 3-3
It is radially outward sequentially distributed along rotary shaft.
Embodiment 7:
Embodiment 7 is similar to Example 1, the difference is that, described time sluice way 3-1 is capillary flow path, itself is to blood
It is hydrophilic capillary flow path or the capillary flow path for doing hydrophily processing for slurry 6-1.
Operation instruction:
Embodiment 7 is similar to Example 1, the difference is that, the 4th step, operation rotation monitor station low speed rotation clockwise, pressure
Compressible medium expansion in the 5-1 of contracting room separates indoor blood plasma 6-1 in the expansive force and capillary stream of discharge chambe 5-1 at this time
It is transferred out under the collective effect of the capillary force in road via second flow channel, working efficiency is higher, and effect is more preferable.
The inventive concept of embodiment 7: by being sequentially connected the inlet chamber 1 of conducting, first runner 2, separation chamber, returning sluice way
3-1, bend 3-2 and aerial drainage runner 3-3, the bend 3-2 and separation chamber are radially outward sequentially distributed along rotary shaft, return sluice way
The outlet of the entrance and aerial drainage runner 3-3 of 3-1 is radially outward sequentially distributed along rotary shaft, and described time sluice way 3-1 is capillary
Runner solves the technical issues of blood plasma and haemocyte in blood separate and transfers out blood plasma, this module is small in size, work effect
Rate is higher, and effect is more preferable.
Embodiment 8:
Embodiment 8 is similar to Example 2, the difference is that, described time sluice way 3-1 is capillary flow path, itself is to blood
It is hydrophilic capillary flow path or the capillary flow path for doing hydrophily processing for slurry 6-1.
Operation instruction:
Embodiment 8 is similar to Example 2, the difference is that, the 4th step, operation rotation monitor station low speed rotation clockwise, pressure
Compressible medium expansion in the 5-1 of contracting room separates indoor blood plasma 6-1 in the expansive force and capillary stream of discharge chambe 5-1 at this time
It is transferred out under the collective effect of the capillary force in road via second flow channel, working efficiency is higher, and effect is more preferable.
The inventive concept of embodiment 8: by being sequentially connected the inlet chamber 1 of conducting, first runner 2, separation chamber, returning sluice way
3-1, bend 3-2 and aerial drainage runner 3-3, the bend 3-2 and separation chamber are radially outward sequentially distributed along rotary shaft, return sluice way
The outlet of the entrance and aerial drainage runner 3-3 of 3-1 is radially outward sequentially distributed along rotary shaft, and the first runner 2 is greater than for flow resistance
The runner of the flow resistance of second flow channel, described time sluice way 3-1 are capillary flow path, solve blood plasma and haemocyte point in blood
From and the technical issues of transfer out blood plasma, this module volume is smaller, and working efficiency is higher, and effect is more preferable.
Explanation of nouns:
In the statement of use " radial direction ", " radial direction " refers to that relative rotation axle center is radial, and the present apparatus or rotor can be with
It is rotated around the axis of rotation.Therefore, in centrifugal field, the direction definition far from axis of rotation be radially outward, and it is close
The direction definition of axis of rotation is radially-inwardly.Similarly, it is referred to as radial inner part close to the part of axis of rotation, and it is remote
It is referred to as radially outer part from the part of axis of rotation.
The common method of surface hydrophilicity processing: such as silicidation, plasma treatment.
Above-mentioned hydrophilic capillary flow path or did hydrophily processing capillary flow path refer to silicidation or
The capillary flow path that plasma treatment is crossed.
In above-described embodiment, the width of flow path size of first runner 2 is more preferably greater than 100um and the runner of first runner 2
More preferably greater than 100um, avoid damage to haemocyte 6-2 causes to influence separating effect height dimension.
Claims (10)
1. the device of suspended solid in a kind of separation fluid, it is characterised in that: including be sequentially connected conducting inlet chamber (1), the
One runner (2), separation chamber and second flow channel, the second flow channel include time sluice way (3-1), bend for being sequentially connected conducting
(3-2) and aerial drainage runner (3-3), described time sluice way (3-1) connect conducting with separation chamber, and the bend (3-2) returns sluice way
The outlet of the entrance and aerial drainage runner (3-3) of (3-1) is radially outward sequentially distributed along rotary shaft.
2. it is according to claim 1 it is a kind of separation fluid in suspended solid device, it is characterised in that: further include with it is described
The third flow channel (4-1) of separation chamber's connection conducting, the third flow channel (4-1) are that third flow channel is connect with the junction of separation chamber
Mouthful, the junction of described time sluice way (3-1) and separation chamber is second flow channel connector (3-4), the third flow channel (4-1),
Third flow channel connector and second flow channel connector (3-4) are radially outward sequentially distributed along rotary shaft.
3. the device of suspended solid in a kind of separation fluid according to claim 1, it is characterised in that: the first runner
(2) it is greater than the runner of the flow resistance of second flow channel for flow resistance.
4. the device of suspended solid in a kind of separation fluid according to claim 2, it is characterised in that: the third flow channel
(4-1) is the runner for the flow resistance that flow resistance is greater than second flow channel.
5. the device of suspended solid in a kind of separation fluid according to claim 1, it is characterised in that: described time sluice way
(3-1) is capillary flow path.
6. the device of suspended solid in a kind of separation fluid according to claim 5, it is characterised in that: the third flow channel
Connector is located in the rotary shaft radially-inwardly separation chamber of side.
7. the device of suspended solid in a kind of separation fluid according to claim 2, it is characterised in that: the second flow channel
Connector (3-4) is located at the middle part of separation chamber, and the third flow channel connector is located at the middle part of separation chamber.
8. the device of suspended solid in a kind of separation fluid according to claim 1, it is characterised in that: the inlet chamber
(1) be radially outward sequentially distributed with separation chamber along rotary shaft, the bend (3-2) and separation chamber along rotary shaft radially outward successively
Distribution.
9. according to claim 1 described in any one of -8 in a kind of separation fluid suspended solid device, it is characterised in that:
The separation chamber includes the discharge chambe (5-1) and mud chamber (5-2) that conducting is radially outward sequentially distributed and connected along rotary shaft, institute
First runner (2) is stated to be connected between inlet chamber (1) and mud chamber (5-2).
10. the device of suspended solid in a kind of separation fluid according to claim 9, it is characterised in that: the separation chamber
It further include retract chamber (5-3), the retract chamber (5-3) is connected between discharge chambe (5-1) and mud chamber (5-2), draws for described time
Runner (3-1) connect conducting with retract chamber (5-3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910289839.4A CN109975102A (en) | 2019-04-11 | 2019-04-11 | The device of suspended solid in a kind of separation fluid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910289839.4A CN109975102A (en) | 2019-04-11 | 2019-04-11 | The device of suspended solid in a kind of separation fluid |
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| CN109975102A true CN109975102A (en) | 2019-07-05 |
Family
ID=67084122
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| Application Number | Title | Priority Date | Filing Date |
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| CN201910289839.4A Pending CN109975102A (en) | 2019-04-11 | 2019-04-11 | The device of suspended solid in a kind of separation fluid |
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| WO2014198703A1 (en) * | 2013-06-10 | 2014-12-18 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Fluid handling apparatus and method for processing a liquid using a diffusion barrier |
| CN105675894A (en) * | 2014-11-20 | 2016-06-15 | 绍兴普施康生物科技有限公司 | Gas-type microfluid detection apparatus and operation method thereof |
| US20190091686A1 (en) * | 2012-12-05 | 2019-03-28 | Radisens Diagnostics Limited | Acceleration-Primed Valving System for Centrifugal Microfluidics |
| CN210090157U (en) * | 2019-04-11 | 2020-02-18 | 石家庄禾柏生物技术股份有限公司 | Device for separating suspended solids in fluid |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2006112993A (en) * | 2004-10-18 | 2006-04-27 | Matsushita Electric Ind Co Ltd | Color bead discriminating device |
| JP2006177751A (en) * | 2004-12-22 | 2006-07-06 | Matsushita Electric Ind Co Ltd | Color bead discrimination device |
| US20190091686A1 (en) * | 2012-12-05 | 2019-03-28 | Radisens Diagnostics Limited | Acceleration-Primed Valving System for Centrifugal Microfluidics |
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