CN109949677A - A kind of blood vessel field simulator - Google Patents
A kind of blood vessel field simulator Download PDFInfo
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- CN109949677A CN109949677A CN201910232527.XA CN201910232527A CN109949677A CN 109949677 A CN109949677 A CN 109949677A CN 201910232527 A CN201910232527 A CN 201910232527A CN 109949677 A CN109949677 A CN 109949677A
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Abstract
This application discloses a kind of blood vessel field simulators, including controller, driving mechanism, blood simulator, simulated organ and logical oxygen device；Blood simulator is used to simulate the environment of the blood of preset temperature；Simulated organ is internally provided with predetermined number phantom channel for characterizing human body certain organs；Controller is used to control the switch of logical oxygen device, to control the amount of oxygen that logical oxygen device is passed through blood simulator, is also used to control driving mechanism movement；Blood after driving blood simulator is interior in conjunction with oxygen when driving mechanism is used to move is input to phantom channel, will pass through the blood oxygen saturation of the measuring instrument being arranged in simulated organ measurement blood, wherein, driving mechanism generates periodically variable driving force when moving, and the variation of driving force is consistent with human body artery blood profile.This application provides relatively reliable and true simulated environment, facilitate the test and calibration of measuring instrument.
Description
Technical field
This application involves field of biomedicine technology, more particularly to a kind of blood vessel field simulator.
Background technique
The real-time monitoring of arterial oxygen saturation is extremely important in clinic rescue.Traditional measurement method of blood oxygen saturation
It is advanced row human blood collection, recycles blood gas analyzer to carry out electrochemical analysis, calculate blood oxygen saturation.This method compares
Trouble, causes secondary injury to patient, and not can be carried out continuous monitoring.Therefore, can real-time, continuous and noninvasive blood oxygen it is full
It is widely studied and is paid close attention to the measuring instrument of degree.
Before measuring instrument investment application, need to be tested by human body or animal number by testing and demarcating
It is tired, and higher cost, required simulated environment is generally provided using simulator.The emulation that current simulator provides
Environment only simply considers blood temperature, and the artery blood pressure of simulation is a steady state value, and the blood pressure of human vas is with a kind of week
Phase property fluctuation status persistently changes, as shown in Figure 1, it is seen then that the simulated environment and human vas that existing simulator provides
True environment deviation it is larger, bring detrimental effect to the test and calibration of measuring instrument.
Therefore, how a kind of scheme can solve above-mentioned technical problem is provided, is that those skilled in the art needs at present
It solves the problems, such as.
Summary of the invention
The purpose of the application is to provide a kind of blood vessel field simulator, provides relatively reliable and true simulated environment,
The test and calibration that instrument can be measured in the case where not by human body or animal are convenient for measuring the test and calibration of instrument.
In order to solve the above technical problems, this application provides a kind of blood vessel field simulator, including controller, driving machine
Structure, blood simulator, simulated organ and logical oxygen device；
The blood simulator is used to simulate the environment of the blood of preset temperature；
The simulated organ is internally provided with predetermined number phantom channel for characterizing human body certain organs；
The controller is used to control the switch of the logical oxygen device, is passed through the blood mould to control the logical oxygen device
The amount of oxygen of quasi- device is also used to control the driving mechanism movement；
Blood after the driving mechanism is used to drive when moving in the blood simulator in conjunction with oxygen is input to
The phantom channel, will pass through the blood oxygen saturation of the measuring instrument being arranged in simulated organ measurement blood, wherein institute
Periodically variable driving force, the variation of the driving force and human body artery blood profile one are generated when stating driving mechanism movement
It causes.
Preferably, the blood simulator includes:
Hold the blood cylinder of blood；The temperature that the temperature of blood in the blood cylinder maintains preset temperature is controlled into mould
Block.
Preferably, the temperature control modules include temperature sensor.
Preferably, the simulated organ is emulation bladder.
Preferably, the predetermined number is the integer greater than 1.
Preferably, the diameter of multiple phantom channels is unequal.
Preferably, the controller is programmable logic controller (PLC) PLC.
Preferably, the driving mechanism is cam-type piston driving mechanism.
Preferably, the logical oxygen device is oxygen cylinder.
Preferably, the simulated organ is silica gel simulated organ.
This application provides a kind of blood vessel field simulators, including controller, driving mechanism, blood simulator, emulation
Organ and logical oxygen device；Blood simulator is used to simulate the environment of the blood of preset temperature；Simulated organ is for characterizing human body
Certain organs are internally provided with predetermined number phantom channel；Controller is used to control the switch of logical oxygen device, to control logical oxygen
Device is passed through the amount of oxygen of blood simulator, is also used to control driving mechanism movement；Driving mechanism is for driving blood when moving
In liquid simulator in conjunction with oxygen after blood be input to phantom channel, will pass through the measuring instrument being arranged in simulated organ
Measure the blood oxygen saturation of blood, wherein driving mechanism generates periodically variable driving force when moving, the variation of driving force with
Human body artery blood profile is consistent.
The blood vessel field simulator of the application is provided and human body artery blood using driving mechanism for blood simulator
The consistent Driving Forces of curvilinear motion, so that into the blood pressure of the blood of phantom channel in simulated organ and human body actual environment
The situation of change of middle blood pressure is consistent, so that relatively reliable and true simulated environment is provided, not by human body or animal
In the case where can measure the test and calibration of instrument, facilitate the test and calibration of measuring instrument.
Detailed description of the invention
It in order to more clearly explain the technical solutions in the embodiments of the present application, below will be to institute in the prior art and embodiment
Attached drawing to be used is needed to be briefly described, it should be apparent that, the accompanying drawings in the following description is only some implementations of the application
Example, for those of ordinary skill in the art, without creative efforts, can also obtain according to these attached drawings
Obtain other attached drawings.
Fig. 1 is a kind of blood pressure curve schematic diagram of human body artery blood vessel provided by the present application；
Fig. 2 is a kind of structural schematic diagram of blood vessel field simulator provided by the present application；
Fig. 3 is the structural schematic diagram of another blood vessel field provided by the present application simulator.
Specific embodiment
The core of the application is to provide a kind of blood vessel field simulator, provides relatively reliable and true simulated environment,
The test and calibration that instrument can be measured in the case where not by human body or animal are convenient for measuring the test and calibration of instrument.
To keep the purposes, technical schemes and advantages of the embodiment of the present application clearer, below in conjunction with the embodiment of the present application
In attached drawing, the technical scheme in the embodiment of the application is clearly and completely described, it is clear that described embodiment is
Some embodiments of the present application, instead of all the embodiments.Based on the embodiment in the application, those of ordinary skill in the art
Every other embodiment obtained without making creative work, shall fall in the protection scope of this application.
Fig. 2 and Fig. 3 are please referred to, Fig. 2 is a kind of structural schematic diagram of blood vessel field simulator provided herein, Fig. 3
For the structural schematic diagram of another blood vessel field provided by the present application simulator, including the simulation of controller 1, driving mechanism 2, blood
Device 3, simulated organ 4 and logical oxygen device 5；
Blood simulator 3 is used to simulate the environment of the blood of preset temperature；
Simulated organ 4 is internally provided with predetermined number phantom channel for characterizing human body certain organs；
Controller 1 is used to control the switch of logical oxygen device 5, to control the oxygen that logical oxygen device 5 is passed through blood simulator 3
Amount is also used to control the movement of driving mechanism 2；
It is logical that blood after driving blood simulator 3 is interior in conjunction with oxygen when driving mechanism 2 is used to move is input to emulation
Road, will pass through the blood oxygen saturation of the measuring instrument being arranged in simulated organ 4 measurement blood, wherein when driving mechanism 2 moves
Periodically variable driving force is generated, the variation of driving force is consistent with human body artery blood profile.
Specifically, in order to solve the problems in the existing technology, this application provides a kind of blood vessel field simulator, packets
Include controller 1, driving mechanism 2, blood simulator 3, simulated organ 4 and logical oxygen device 5, wherein controller 1 can be electrical
Controller, in the case that in blood vessel field, simulator is powered on, controller 1 can be such that driving mechanism 2 rotates, and driving mechanism 2 rotates
When, driving force is generated to blood simulator 3, and in blood simulator 3 it is the blood of preset temperature, such as 36 DEG C, in blood
Containing can be with the hemoglobin in conjunction with oxygen.Under the action of driving force, the blood in blood simulator 3 is input to emulator
In the phantom channel of official 4, so as to the blood oxygen saturation of the measuring instrument measurement blood in simulated organ 4.
It should be noted that measuring instrument here can be by being made based on volumetric blood principle and spectrophotometry principle
Sensor, have the advantages that real-time, noninvasive and continuous.Specifically, the measuring principle of noninvasive arterial oxygen saturation includes blood
Liquid volume principle and spectrophotometry principle two parts.Spectrophotometry is according to oxyhemoglobin (Sp02) and reduction
The absorption characteristic of hemoglobin (Hb) is different and obtains oximetry value.Reduced hemoglobin inhales the feux rouges of 660nm wavelength
Receipts amount is less, more to the infrared Absorption amount of 940nm wavelength；And oxyhemoglobin (Sp02) is to the feux rouges of 660nm wavelength
Uptake is less, more to the infrared Absorption amount of 940nm wavelength.In addition, the other compositions in tissue, such as venous blood, bone
The light quantity of the absorptions such as bone, skin and muscle is constant, but oxyhemoglobin and reduced hemoglobin are to light in blood
Absorption is changed as pulse wave cycle changes.Heart shrink when, periphery blood volume is most, blood to absorbing amount most
Greatly, the light energy that detected is minimum；And it is on the contrary therewith when diastole.Blood reflects bleeding to the variation of absorbing amount
The variation of capacity, therefore the blood volume of only artery can just obtain the intensity of illumination of variation, here it is volumetric blood principles.This two
Kind characteristic, provides theoretical foundation for the measurement of blood oxygen saturation.According to the difference of acquisition mode used in sensor, sensing
Device can be divided into transmission sensors and two kinds of reflection sensor, and the blood vessel field simulator of the application is suitable for both biographies
Sensor.
Certainly, measuring instrument in addition to transmission-type and it is reflective other than, can also be other, the application does not do special limit herein
It is fixed.
This application provides a kind of blood vessel field simulators, including controller, driving mechanism, blood simulator, emulation
Organ and logical oxygen device；Blood simulator is used to simulate the environment of the blood of preset temperature；Simulated organ is for characterizing human body
Certain organs are internally provided with predetermined number phantom channel；Controller is used to control the switch of logical oxygen device, to control logical oxygen
Device is passed through the amount of oxygen of blood simulator, is also used to control driving mechanism movement；Driving mechanism is for driving blood when moving
In liquid simulator in conjunction with oxygen after blood be input to phantom channel, will pass through the measuring instrument being arranged in simulated organ
Measure the blood oxygen saturation of blood, wherein driving mechanism generates periodically variable driving force when moving, the variation of driving force with
Human body artery blood profile is consistent.
The blood vessel field simulator of the application is provided and human body artery blood using driving mechanism for blood simulator
The consistent Driving Forces of curvilinear motion, so that into the blood pressure of the blood of phantom channel in simulated organ and human body actual environment
The situation of change of middle blood pressure is consistent, so that relatively reliable and true simulated environment is provided, not by human body or animal
In the case where can measure the test and calibration of instrument, facilitate the test and calibration of measuring instrument.
On the basis of the above embodiments:
Embodiment as one preferred, blood simulator 3 include:
Hold the blood cylinder of blood；The temperature of blood in blood cylinder is maintained to the temperature control modules of preset temperature.
Specifically, in order to simulate environment locating for blood of human body, the blood simulator 3 of the application may include blood cylinder
With temperature control modules, wherein temperature control modules are connect with controller 1, when the temperature of blood in blood cylinder is lower than default temperature
When spending, under the control of controller 1, temperature control modules are heated to blood cylinder, until the temperature of blood reaches default in blood cylinder
Temperature.
It should be noted that blood simulator 3 can also exist other than above structure for other structures, the application
This is not particularly limited.
Embodiment as one preferred, temperature control modules include temperature sensor.
Specifically, blood simulator 3 is during maintaining this of preset temperature for the temperature of blood, temperature control
Module can be with the temperature of blood in real-time detection blood cylinder, and for the ease of detection, the application can be using with temperature detection function
The temperature sensor of energy, such as can be DHT11 digital temperature sensor, with responding, fast, strong antijamming capability, data are smart
Spend high feature.
Certainly, other than aforesaid way, it can also realize that above-mentioned function, the application are not spy herein using other modes
Other restriction.
Embodiment as one preferred, simulated organ 4 are emulation bladder.
Specifically, the simulated organ 4 of the application can be emulation bladder, and simulated organ 4 is different, and simulated environment might have
Institute is different, and blood pressure is also different, and driving mechanism 2 also will adaptably change.When simulated organ 4 is emulation bladder, the application
For can be carried out inside human bladder blood oxygen saturation data acquisition oxygen saturation measurement instrument precision calibration or test mention
Next step can be just carried out after oxygen saturation measurement instrument is by test and precision calibration for a kind of blood vessel field simulated environment
Human clinical trial.
Certainly, other than emulating bladder, simulated organ 4 can also be other, and the application is not particularly limited herein.
Embodiment as one preferred, predetermined number are the integer greater than 1.
Specifically, in order to provide the simulated environment of closer human body actual organ a kind of, the phantom channel of the application is more
It is a.Since there are many blood vessel in human organ, one blood vessel field of many blood vessels compositions, rather than single vessel, if only with one
A phantom channel carrys out simulated blood vessel, larger with actual environment gap, therefore, in order to be more nearly the environment tested and demarcated very
Real human body environment, quantity of the quantity of the application phantom channel as far as possible with human organ medium vessels are consistent.
The diameter of embodiment as one preferred, multiple phantom channels is unequal.
Specifically, in order to be laid out further to blood vessel in human body actual organ multiple emulation of the case where, the application are logical
The diameter in road is unequal, it is contemplated that the thickness of blood vessel is not identical in human organ, and therefore, phantom channel can root
It is set as different diameters according to the actual conditions of human organ, so that the test of measuring instrument and calibration result are more acurrate.
It should be noted that simulated organ 4 can also improve in terms of other to connect other than considering from diameter and quantity
Nearly actual human body environment, such as material, the application are not particularly limited herein.
Embodiment as one preferred, controller 1 are that (Programmable Logic Controller, can compile PLC
Journey logic controller).
Specifically, for the ease of control, the controller 1 of the application can be PLC, compared with other controllers 1, PLC tool
There is the advantages that at low cost, high reliablity, strong antijamming capability.
In addition, controller 1 can also be other, and the application is not particularly limited herein other than PLC.
Embodiment as one preferred, driving mechanism 2 are cam-type piston driving mechanism.
Specifically, in order to provide a kind of simulated environment of closer human organ true environment, guarantee measuring instrument test with
The driving mechanism 2 of the accuracy of calibration, the application can be cam-type piston driving mechanism, in order to make cam-type piston driving machine
Structure is capable of providing the driving force consistent with the variation of human body artery blood profile in Fig. 1, the cam-type piston driving of the application
The cam profile of mechanism can be consistent with human body artery blood profile in Fig. 1, turns in this way with cam-type piston driving mechanism
It is dynamic that periodically variable driving force can be generated to blood cylinder, for example decline after the rising of systole phase driving force reaches maximum,
Diastole driving force is gradually reduced, and the blood pressure of blood also can be with the variation phase one of blood pressure in human organ in such blood cylinder
It causes, it is seen then that the blood vessel field simulator of the application can simulate the cyclic fluctuation state of blood pressure, be more nearly real human body
The pulse wave phenomenon of blood pressure in blood.
It should be noted that driving mechanism 2 can also be other, and the application exists other than cam-type piston driving mechanism
This is not particularly limited.
Embodiment as one preferred, leading to oxygen device 5 is oxygen cylinder.
Specifically, it is contemplated that the oxygen carrying capacity of different human body is different, causes blood sample concentration in blood different, i.e., blood oxygen is saturated
Degree is different, therefore, in order to simulate different human body same organs environment, convenient for test and calibration measuring instrument, blood simulation dress
Setting 3 it is also required to provide the blood of different blood sample concentration.The application is passed through in blood simulator 3 by changing logical oxygen device 5
Amount of oxygen, so that the combination degree of blood also oxygen is different, to provide the blood of different blood oxygen concentrations.
In view of convenience, the logical oxygen device 5 of the application can be oxygen cylinder, as shown in figure 3, generally having out on oxygen cylinder
It closes, controller 1 can control the amount of oxygen being passed through by the time span that control switch is opened, and this implementation is simple and square
Just.
Certainly, leading to oxygen device 5 can be oxygen cylinder, or other, the application is not particularly limited herein.
Embodiment as one preferred, simulated organ 4 are silica gel simulated organ.
Specifically, in order to provide a kind of simulated environment of closer human organ true environment, simulated organ 4 can be silicon
Closed simulated organ 4 made of glue can be machined with similar human body when making closed simulated organ 4 in colloidal silica
The phantom channel of different thicknesses blood vessel in organ.Closed simulated organ 4 provides the blood vessel field ring of test and calibration for measuring instrument
Border.
It should be noted that the material of simulated organ 4 can be silica gel, it can also be other, the application is not spy herein
Other restriction.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other
The difference of embodiment, the same or similar parts in each embodiment may refer to each other.For method disclosed in embodiment
For, since it is corresponding with system disclosed in embodiment, so being described relatively simple, related place is defended oneself referring to Account Dept
It is bright.
It should also be noted that, in the present specification, relational terms such as first and second and the like be used merely to by
One entity or operation are distinguished with another entity or operation, without necessarily requiring or implying these entities or operation
Between there are any actual relationship or orders.Moreover, the terms "include", "comprise" or its any other variant meaning
Covering non-exclusive inclusion, so that the process, method, article or equipment for including a series of elements not only includes that
A little elements, but also including other elements that are not explicitly listed, or further include for this process, method, article or
The intrinsic element of equipment.In the absence of more restrictions, being wanted by what sentence " including one " limited
Element, it is not excluded that there is also other identical elements in the process, method, article or apparatus that includes the element.
The foregoing description of the disclosed embodiments makes professional and technical personnel in the field can be realized or use the application.
Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the application.Therefore, the application
It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one
The widest scope of cause.
Claims (10)
1. a kind of blood vessel field simulator, which is characterized in that including controller, driving mechanism, blood simulator, simulated organ
With logical oxygen device；
The blood simulator is used to simulate the environment of the blood of preset temperature；
The simulated organ is internally provided with predetermined number phantom channel for characterizing human body certain organs；
The controller is used to control the switch of the logical oxygen device, is passed through the blood simulation dress to control the logical oxygen device
The amount of oxygen set is also used to control the driving mechanism movement；
The driving mechanism is input to described for the blood after driving the blood simulator interior in conjunction with oxygen when moving
Phantom channel, will pass through the blood oxygen saturation of the measuring instrument being arranged in simulated organ measurement blood, wherein the drive
Periodically variable driving force is generated when dynamic mechanism kinematic, the variation of the driving force is consistent with human body artery blood profile.
2. blood vessel field according to claim 1 simulator, which is characterized in that the blood simulator includes:
Hold the blood cylinder of blood；The temperature of blood in the blood cylinder is maintained to the temperature control modules of preset temperature.
3. blood vessel field according to claim 2 simulator, which is characterized in that the temperature control modules include that temperature passes
Sensor.
4. blood vessel field according to claim 1 simulator, which is characterized in that the simulated organ is emulation bladder.
5. blood vessel field according to claim 1 simulator, which is characterized in that the predetermined number is the integer greater than 1.
6. blood vessel field according to claim 5 simulator, which is characterized in that the diameter of multiple phantom channels not phase
Deng.
7. blood vessel field according to claim 6 simulator, which is characterized in that the controller is Programmable logical controller
Device PLC.
8. blood vessel field according to claim 1-7 simulator, which is characterized in that the driving mechanism is cam
Formula piston drive mechanism.
9. blood vessel field according to claim 8 simulator, which is characterized in that the logical oxygen device is oxygen cylinder.
10. blood vessel field according to claim 9 simulator, which is characterized in that the simulated organ is silica gel emulator
Official.
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| CN201910232527.XA CN109949677B (en) | 2019-03-26 | 2019-03-26 | Vascular field simulation device |
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| CN201910232527.XA CN109949677B (en) | 2019-03-26 | 2019-03-26 | Vascular field simulation device |
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| CN113409667A (en) * | 2021-06-21 | 2021-09-17 | 中国人民解放军陆军军医大学 | Device for simulating aortic blood spraying |
| CN113706984A (en) * | 2021-08-06 | 2021-11-26 | 西安交通大学 | Synchronous analog calibration device and method for blood pressure and reflection type photoelectric accumulated wave |
| CN113855013A (en) * | 2021-09-28 | 2021-12-31 | 杭州大牧医疗科技有限公司 | Probe conversion device of blood oxygen simulator |
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| CN109949677B (en) | 2021-07-13 |
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