CN109945997A - A kind of faint circuit for amplifying differential signal and device of medical pressure sensor - Google Patents

A kind of faint circuit for amplifying differential signal and device of medical pressure sensor Download PDF

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CN109945997A
CN109945997A CN201910258377.XA CN201910258377A CN109945997A CN 109945997 A CN109945997 A CN 109945997A CN 201910258377 A CN201910258377 A CN 201910258377A CN 109945997 A CN109945997 A CN 109945997A
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China
Prior art keywords
signal
circuit
pressure sensor
stage
medical pressure
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CN201910258377.XA
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Inventor
袁刚
张明明
吴中毅
郑健
刘兆邦
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Suzhou Smaiev Technology Co Ltd
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Suzhou Smaiev Technology Co Ltd
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Priority to CN201910258377.XA priority Critical patent/CN109945997A/en
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Abstract

The present invention provides a kind of faint circuit for amplifying differential signal of medical pressure sensor, including first order amplifying circuit, second level amplifying circuit, add circuit.The invention further relates to the faint differential signal amplifying devices of medical pressure sensor.The present invention uses two-stage amplifying circuit and add circuit, realizes the amplification of medical pressure sensor differential signal, provides solid foundation to medical sensor small-signal real-time detection, realizes the microvolt detection of medical pressure signal.The present invention improves nursing efficiency in the application of medical nursing using wireless communication, reduces nursing work load, and as clinical and academic research tool;The real-time storage to data is realized simultaneously, is provided data for medical research and is supported.

Description

Weak differential signal amplification circuit and device of medical pressure sensor
Technical Field
The invention relates to signal acquisition of a medical sensor, in particular to a weak differential signal amplification circuit and a weak differential signal amplification device of a medical pressure sensor.
Background
In the field of medical detection, various sensors, especially pressure sensors, are often used, and because signals detected by the medical pressure sensors are often very weak and the signals change violently, the traditional signal amplification circuit cannot meet the requirements of medical detection.
On the other hand, in traditional hospital clinical application, many hands are often needed to perform detection operation of the medical pressure sensor, and detection accuracy and detection positions are different for different cases and different detection times. In the traditional method, a doctor and a nurse judge data detected by a sensor according to experience, and the state of a patient needs to be cared at any time; not only excessively depends on the experience of doctors and nurses, but also limits the working mode of medical staff and reduces the use efficiency of medical resources.
Therefore, a weak differential signal amplifying circuit and a device for a novel medical pressure sensor are urgently needed.
Disclosure of Invention
In order to overcome the defects of the prior art, the weak differential signal amplifying circuit of the medical pressure sensor provided by the invention adopts a two-stage amplifying circuit and an adding circuit to realize the amplification of the differential signal of the medical pressure sensor, provides a solid foundation for the real-time detection of the weak signal of the medical sensor and realizes the microvolt detection of the medical pressure signal.
The invention provides a weak differential signal amplifying circuit of a medical pressure sensor, which comprises a first-stage amplifying circuit, a second-stage amplifying circuit and an adding circuit, wherein the first-stage amplifying circuit is connected with the second-stage amplifying circuit; wherein,
the first-stage amplifying circuit is used for receiving the differential signal of the medical pressure sensor and carrying out first-stage amplification on the differential signal of the medical pressure sensor to obtain a first-stage amplified signal;
the second-stage amplifying circuit is used for receiving the first-stage amplified signal, filtering the first-stage amplified signal and performing second-stage amplification to obtain a second-stage amplified signal;
the addition circuit is used for receiving the second amplified signal and superposing a constant direct current voltage on the second amplified signal so as to enable the addition circuit to output a positive voltage signal which can be subjected to digital-to-analog conversion.
Preferably, the first stage of amplifying circuit further comprises a low-pass filter circuit for filtering out high-frequency noise.
Preferably, the first-stage amplifying circuit adopts a preamplifier U12; the second-stage amplifying circuit adopts a preamplifier U13, and the amplification gains of the preamplifiers U12 and U13 are 1-1000 times.
Preferably, a second-order passive filter circuit is configured between the first-stage amplification circuit and the second-stage amplification circuit and behind the addition circuit.
Preferably, the addition circuit adopts a potentiometer P11, and the output voltage of the second pin of the potentiometer P11 is greater than or equal to-5V and less than or equal to 5V; the negative pressure of the preamplifiers U12, U13 and the potentiometer P11 is provided by a negative pressure chip LM 2662.
A weak differential signal amplification device of a medical pressure sensor comprises a main control unit, a conversion module, a signal amplification module and a wireless communication module; the main control unit is electrically connected with the conversion module and the wireless communication module, and the signal amplification module is electrically connected with the conversion module; wherein,
the signal amplification module is internally provided with a weak differential signal amplification circuit of the medical pressure sensor as claimed in claim 1: the signal amplification module is used for receiving the differential signal of the medical pressure sensor, amplifying the signal and inputting the amplified signal to the conversion module; the conversion module is used for receiving the amplified signal, converting the signal into a digital signal and inputting the digital signal to the main control unit; the main control unit analyzes the digital signal and sends the digital signal to external communication equipment through the wireless communication module.
Preferably, the main control unit adopts an STM32 singlechip; the conversion module is an ADC digital-to-analog conversion circuit.
Preferably, the device further comprises a display module; the display module is electrically connected with the main control unit; the display module comprises an OLED display module or an LCD display module.
Preferably, the wireless communication module includes a bluetooth communication module, a WIFI communication module or a zigbee module.
Preferably, the device further comprises a storage module, wherein the storage module is electrically connected with the main control unit and used for storing digital signals; the storage module comprises a U disk, a CF card, an SD card, an SDHC card, an MMC card, an SM card, a memory stick and an xD card.
Compared with the prior art, the invention has the beneficial effects that:
the invention provides a weak differential signal amplifying circuit of a medical pressure sensor, which comprises a first-stage amplifying circuit, a second-stage amplifying circuit and an adding circuit, wherein the first-stage amplifying circuit is connected with the second-stage amplifying circuit; the first-stage amplifying circuit is used for receiving the differential signal of the medical pressure sensor and carrying out first-stage amplification on the differential signal of the medical pressure sensor to obtain a first-stage amplified signal; the second-stage amplifying circuit is used for receiving the first-stage amplified signal, filtering the first-stage amplified signal and performing second-stage amplification to obtain a second-stage amplified signal; the addition circuit is used for receiving the second amplified signal and superposing a constant direct-current voltage on the second amplified signal so as to enable the addition circuit to output a positive voltage signal which can be subjected to digital-to-analog conversion. The invention also relates to a weak differential signal amplifying device of the medical pressure sensor. The differential signal amplification circuit adopts a two-stage amplification circuit and an addition circuit to realize the differential signal amplification of the medical pressure sensor, provides a solid foundation for the real-time detection of the weak signal of the medical sensor and realizes the microvolt detection of the medical pressure signal. The wireless communication is adopted, so that the nursing efficiency is improved, the nursing workload is reduced in the application of medical nursing, and the wireless communication is used as a favorable tool for clinical and academic research; meanwhile, real-time data storage is realized, and data support is provided for medical research.
The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical solutions of the present invention more clearly understood and to implement them in accordance with the contents of the description, the following detailed description is given with reference to the preferred embodiments of the present invention and the accompanying drawings. The detailed description of the present invention is given in detail by the following examples and the accompanying drawings.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention without limiting the invention. In the drawings:
FIG. 1 is a schematic diagram of a weak differential signal amplifying circuit of a medical pressure sensor according to the present invention;
FIG. 2 is a schematic diagram of a modular weak differential signal amplification apparatus of a medical pressure sensor according to the present invention;
FIG. 3 is a circuit diagram of a weak differential signal amplification circuit of a medical pressure sensor according to an embodiment of the present invention;
FIG. 4 is a negative voltage circuit diagram of a weak differential signal amplifying circuit of a medical pressure sensor according to an embodiment of the present invention;
FIG. 5 is a first power circuit diagram of a weak differential signal amplifying device of a medical pressure sensor according to an embodiment of the present invention;
FIG. 6 is a second power circuit diagram of a weak differential signal amplifying device of a medical pressure sensor according to an embodiment of the present invention;
FIG. 7 is a reference power circuit diagram of an ADC DAC circuit according to an embodiment of the present invention;
fig. 8 is a circuit diagram of a master control unit according to an embodiment of the invention.
Detailed Description
The present invention will be further described with reference to the accompanying drawings and the detailed description, and it should be noted that any combination of the embodiments or technical features described below can be used to form a new embodiment without conflict.
A weak differential signal amplifying circuit of a medical pressure sensor is shown in figure 1 and comprises a first-stage amplifying circuit, a second-stage amplifying circuit and an adding circuit; wherein,
the first-stage amplifying circuit is used for receiving the differential signal of the medical pressure sensor and carrying out first-stage amplification on the differential signal of the medical pressure sensor to obtain a first-stage amplified signal;
the second-stage amplifying circuit is used for receiving the first-stage amplified signal, filtering the first-stage amplified signal and performing second-stage amplification to obtain a second-stage amplified signal;
the addition circuit is used for receiving the second amplified signal and superposing a constant direct-current voltage on the second amplified signal so as to enable the addition circuit to output a positive voltage signal which can be subjected to digital-to-analog conversion.
In this embodiment, the differential signal of the medical pressure sensor is a microvolt signal, and since the signal variation range is large, the amplification stages of the conventional amplification circuit are multiple, and signal distortion exist. In this embodiment, two-stage amplification is adopted, as shown in fig. 3, signals are led out from the second and third pins of P6, and weak differential signals are filtered by first-order low-pass filtering to remove high-frequency noise; as shown in fig. 3, the first-order low-pass filter circuit includes resistors R41, R46, capacitors C41, C42, and C47;
in one embodiment, as shown in FIG. 3, the first stage of amplification circuitry employs a preamplifier U12; the second stage of amplifying circuit adopts a preamplifier U13, and the amplifying gain of the preamplifiers U12 and U13 is 1-1000 times. In the embodiment, the preamplifier adopts an AD623, the AD623 is an integrated instrument preamplifier, and the AD623 is set to be a unit gain under the condition of no external resistor; after the resistor is externally connected, the AD623 can be programmed to set the gain, the gain can reach 1000 times at most, and the amplification times are adjusted to 100 times; for example, the full-scale output electric signal range of P6 is-350 uV-1700 uV, and a first amplified signal with the range of-35 mV-170 mV is obtained after the electric signal is amplified by a preamplifier U12; the first-time amplified signal also belongs to a weak signal, the second-stage amplifying circuit uses an instrument preamplifier AD623, the second-stage amplified signal is input into the second-stage amplifier AD623 after second-order passive filtering, the second-stage amplification is adjusted to 10 times through a resistor for amplification, and the second-time amplified signal with the range of-0.35V-1.7V is obtained after the second-stage amplification; as shown in fig. 3, the second-order passive filter circuit includes resistors R42, R43, capacitors C51, C45, and C46, and filters out amplified noise.
In one embodiment, as shown in fig. 3, the adder circuit employs a potentiometer P11, and the output voltage of the second pin of the potentiometer P11 is greater than or equal to-5V and less than or equal to 5V; the negative voltages of the preamplifiers U12, U13 and the potentiometer P11 are provided through a negative voltage chip LM 2662. As shown in fig. 4, the chip U11 is a negative chip LM2662, wherein a capacitor C39 is connected in series between the second pin and the fourth pin of U11; the negative voltage output is a fifth pin which is respectively connected with the fourth pin of U12, the fourth pin of U13 and the third pin of P11 and is used as the negative voltage output. In one embodiment, V in the summing circuitREFThe voltage is overlapped with a voltage of 1V through a potentiometer P11, and the range of minus 0.35V to 1.7V is increased to the range0.65V-2.7V, the signal is used for inputting to the conversion module for digital-to-analog conversion; in a preferred embodiment, a second-order passive filter circuit is further arranged between the addition circuit and the conversion module and used for filtering noise waves after voltage boosting; as shown in fig. 3, the second-order passive filter circuit includes resistors R44, R45, capacitors C43, C44, and C50; the signal output from ADCCH1 is a signal that enters the conversion module for digital-to-analog conversion.
A weak differential signal amplification device of a medical pressure sensor, as shown in fig. 2, comprises a main control unit, a conversion module, a signal amplification module and a wireless communication module; the main control unit is electrically connected with the conversion module and the wireless communication module, and the signal amplification module is electrically connected with the conversion module; wherein,
a weak differential signal amplifying circuit of the medical pressure sensor is configured in the signal amplifying module: the signal amplification module is used for receiving the differential signal of the medical pressure sensor, amplifying the signal and inputting the amplified signal to the conversion module; the conversion module is used for receiving the amplified signal, converting the amplified signal into a digital signal and inputting the digital signal to the main control unit; the main control unit analyzes the digital signal and sends the digital signal to external communication equipment through the wireless communication module.
In one embodiment, the main control unit adopts an STM32 singlechip; the conversion module is an ADC digital-to-analog conversion circuit. The main control unit adopts an STM32F103C8T6, and as shown in FIG. 8, comprises a main chip, a crystal oscillator circuit, a filter circuit and an isolation circuit; simultaneously, the system comprises a reading ADC digital-to-analog conversion SPI circuit, an OLED display SPI circuit, an SD card storage SPI circuit and a Bluetooth communication circuit. In a preferred embodiment, as shown in fig. 5 and 6, for the main control unit power circuit, the DC-DC conversion chip MP2359 in fig. 5 converts the voltage into DC5V to provide 5V DC power for the main control unit; the DC-DC chip AMS1117 in fig. 6 converts a 5V DC voltage into 3.3V, and provides a 3.3V DC power supply to the main control unit.
In one embodiment, the reference power circuit of the ADC digital-to-analog conversion circuit is shown in fig. 7, and includes a chip ADR03B and an OPA 350; wherein ADR03B converts DC5V to DC2.5V; the OPA350 forms a voltage follower circuit, the voltage follower circuit comprises the OPA350, capacitors C52, C53, C54, C55, C56 and a resistor R50, the wiring condition is shown in fig. 7, and finally, a reference power supply ADCREF is provided for the ADC digital-to-analog conversion circuit.
In one embodiment, the device further comprises a display module; the display module is electrically connected with the main control unit; the display module includes an OLED display module or an LCD display module. The working condition of the weak differential signal amplifying device of the medical pressure sensor is visually observed by adopting a visual mode, so that the medical staff and the patient can use the device conveniently.
In one embodiment, the wireless communication module includes a bluetooth communication module, a WIFI communication module, or a zigbee module. In medical care applications, improve care efficiency, reduce care workload, and can be a beneficial tool for clinical and academic research. Particularly, the weak differential signal amplification device of the medical pressure sensor is also provided with a storage module, and the storage module is electrically connected with the main control unit and used for storing digital signals; the storage module comprises a U disk, a CF card, an SD card, an SDHC card, an MMC card, an SM card, a memory stick and an xD card; the data can be stored in real time, and data support is provided for medical research.
The invention provides a weak differential signal amplifying circuit of a medical pressure sensor, which comprises a first-stage amplifying circuit, a second-stage amplifying circuit and an adding circuit, wherein the first-stage amplifying circuit is connected with the second-stage amplifying circuit; the first-stage amplifying circuit is used for receiving the differential signal of the medical pressure sensor and carrying out first-stage amplification on the differential signal of the medical pressure sensor to obtain a first-stage amplified signal; the second-stage amplifying circuit is used for receiving the first-stage amplified signal, filtering the first-stage amplified signal and performing second-stage amplification to obtain a second-stage amplified signal; the addition circuit is used for receiving the second amplified signal and superposing a constant direct-current voltage on the second amplified signal so as to enable the addition circuit to output a positive voltage signal which can be subjected to digital-to-analog conversion. The invention also relates to a weak differential signal amplifying device of the medical pressure sensor. The differential signal amplification circuit adopts a two-stage amplification circuit and an addition circuit to realize the differential signal amplification of the medical pressure sensor, provides a solid foundation for the real-time detection of the weak signal of the medical sensor and realizes the microvolt detection of the medical pressure signal. The wireless communication is adopted, so that the nursing efficiency is improved, the nursing workload is reduced in the application of medical nursing, and the wireless communication is used as a favorable tool for clinical and academic research; meanwhile, real-time data storage is realized, and data support is provided for medical research.
The foregoing is merely a preferred embodiment of the invention and is not intended to limit the invention in any manner; those skilled in the art can readily practice the invention as shown and described in the drawings and detailed description herein; however, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the scope of the invention as defined by the appended claims; meanwhile, any changes, modifications, and evolutions of the equivalent changes of the above embodiments according to the actual techniques of the present invention are still within the protection scope of the technical solution of the present invention.

Claims (10)

1. A weak differential signal amplifying circuit of a medical pressure sensor is characterized by comprising a first-stage amplifying circuit, a second-stage amplifying circuit and an adding circuit; wherein,
the first-stage amplifying circuit is used for receiving the differential signal of the medical pressure sensor and carrying out first-stage amplification on the differential signal of the medical pressure sensor to obtain a first-stage amplified signal;
the second-stage amplifying circuit is used for receiving the first-stage amplified signal, filtering the first-stage amplified signal and performing second-stage amplification to obtain a second-stage amplified signal;
the addition circuit is used for receiving the second amplified signal and superposing a constant direct current voltage on the second amplified signal so as to enable the addition circuit to output a positive voltage signal which can be subjected to digital-to-analog conversion.
2. The weak differential signal amplifying circuit of medical pressure sensor as claimed in claim 1, wherein: the low-pass filter circuit is arranged in front of the first-stage amplifying circuit and used for filtering high-frequency clutter.
3. The weak differential signal amplifying circuit of medical pressure sensor as claimed in claim 1, wherein: the first-stage amplifying circuit adopts a preamplifier U12; the second-stage amplifying circuit adopts a preamplifier U13, and the amplification gains of the preamplifiers U12 and U13 are 1-1000 times.
4. The weak differential signal amplification circuit of a medical pressure sensor as claimed in any one of claims 1-3, wherein: and a second-order passive filter circuit is configured between the first-stage amplifying circuit and the second-stage amplifying circuit and behind the addition circuit.
5. The weak differential signal amplifying circuit of medical pressure sensor as claimed in claim 3, wherein: the addition circuit adopts a potentiometer P11, and the output voltage of a second pin of the potentiometer P11 is greater than or equal to-5V and less than or equal to 5V; the negative pressure of the preamplifiers U12, U13 and the potentiometer P11 is provided by a negative pressure chip LM 2662.
6. A weak differential signal amplification device of a medical pressure sensor is characterized by comprising a main control unit, a conversion module, a signal amplification module and a wireless communication module; the main control unit is electrically connected with the conversion module and the wireless communication module, and the signal amplification module is electrically connected with the conversion module; wherein,
the signal amplification module is internally provided with a weak differential signal amplification circuit of the medical pressure sensor as claimed in claim 1: the signal amplification module is used for receiving the differential signal of the medical pressure sensor, amplifying the signal and inputting the amplified signal to the conversion module; the conversion module is used for receiving the amplified signal, converting the signal into a digital signal and inputting the digital signal to the main control unit; the main control unit analyzes the digital signal and sends the digital signal to external communication equipment through the wireless communication module.
7. The weak differential signal amplifying device of medical pressure sensor as claimed in claim 6, wherein: the main control unit adopts an STM32 singlechip; the conversion module is an ADC digital-to-analog conversion circuit.
8. The weak differential signal amplifying device of medical pressure sensor as claimed in claim 6, wherein: the device also comprises a display module; the display module is electrically connected with the main control unit; the display module comprises an OLED display module or an LCD display module.
9. The weak differential signal amplifying device of medical pressure sensor as claimed in claim 6, wherein: the wireless communication module comprises a Bluetooth communication module, a WIFI communication module or a zigbee module.
10. The weak differential signal amplifying device of medical pressure sensor as claimed in claim 6, wherein: the storage module is electrically connected with the main control unit and used for storing digital signals; the storage module comprises a U disk, a CF card, an SD card, an SDHC card, an MMC card, an SM card, a memory stick and an xD card.
CN201910258377.XA 2019-04-01 2019-04-01 A kind of faint circuit for amplifying differential signal and device of medical pressure sensor Pending CN109945997A (en)

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US20090018458A1 (en) * 2007-07-13 2009-01-15 Dimetek Digital Medical Technologies, Ltd. Pure digital medical amplifier for digitally acquiring, conditioning, storing, and transferring clinical and non-clinical biomedical signals
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CN104897953A (en) * 2015-01-30 2015-09-09 中天储能科技有限公司 Accurate lithium battery BMS system charging and discharging current sampling and calculation circuit and control method
CN106556717A (en) * 2015-09-24 2017-04-05 祁艳 A kind of highly sensitive accelerometer weak signal extraction circuit
CN107070424A (en) * 2017-03-10 2017-08-18 天津工业大学 A kind of pre-amplification circuit of pulse signal process chip
CN209706984U (en) * 2019-04-01 2019-11-29 苏州斯玛维科技有限公司 A kind of faint circuit for amplifying differential signal and device of medical pressure sensor

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090018458A1 (en) * 2007-07-13 2009-01-15 Dimetek Digital Medical Technologies, Ltd. Pure digital medical amplifier for digitally acquiring, conditioning, storing, and transferring clinical and non-clinical biomedical signals
CN104897953A (en) * 2015-01-30 2015-09-09 中天储能科技有限公司 Accurate lithium battery BMS system charging and discharging current sampling and calculation circuit and control method
CN104706360A (en) * 2015-03-02 2015-06-17 深圳市科曼医疗设备有限公司 Respiration monitoring device and method
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