CN109939025A - A kind of skin cream of opponent's foot chapped skin repair function - Google Patents
A kind of skin cream of opponent's foot chapped skin repair function Download PDFInfo
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- CN109939025A CN109939025A CN201910222968.1A CN201910222968A CN109939025A CN 109939025 A CN109939025 A CN 109939025A CN 201910222968 A CN201910222968 A CN 201910222968A CN 109939025 A CN109939025 A CN 109939025A
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- skin
- foot
- opponent
- repair function
- chapped
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Abstract
The present invention relates to a kind of skin cream of opponent's foot chapped skin repair function, it mainly include following components and its weight percentage: Garcinia indica seed rouge 5%-10%, egg oil 3%-8%, phytosterol isostearate 0.5%-2%, soluble protein polysaccharide 0.1%-1%, chitosan list succinamide 0.5%-2.5%, synthesize quasi-grease 3%-6%, emulsifier 2%-6%, thickener 2%-5%, moisturizer 3%-15%, preservative 0.6%-3%, antioxidant 0.5%-2%, neutralizer 0.1%-1%, deionized water add to 100%.The present invention is by Garcinia indica seed rouge, egg oil, phytosterol isostearate, soluble protein polysaccharide, chitosan list succinamide is used cooperatively, and is acted synergistically mutually, reasonable to select each component and its content, with preferable moisturizing and moisture-keeping efficacy, promote skin metabolism, inhibit scytitis, can effectively repair trick chapped skin, not increase burden to skin and effect is lasting, safe without toxic side effect is suitble to various crowds to use.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of skin cream of opponent's foot chapped skin repair function.
Background technique
Winter climate is cold and dries, as northwest blows air over, the brothers of people by it is wet switch to it is coarse.This is because hand
The palm and heel, almost without sebaceous glands.Into winter, temperature is gradually reduced, and the secretion of sebaceous glands is also just reduced therewith, however hand
It is often exposed with foot, rapid heat dissipation, along with often there are cold air invasion in winter, the heat and grease of hand and foot vapor away quickly
, trick hair shaft is made one, if be not protected, breach easily occurs, serious person there is also pain, bleeding, medically claim
Be " fissura ".
Garcinia indica seed oil derives from the seed of Garcinia indica, containing abundant fatty acid and vitamin E, can heal dry and cracked
Lip, hand and foot restore the elasticity of skin and continue cell senescence, increase cell oxygen content, penetration is stronger, and can releive
Skin mitigates sunburn, dry and cracked caused sense of discomfort.
Egg oil is the product that egg yolk is obtained by carbon dioxide low temperature supercritical extract, completely remains yolk
Middle heat-sensitive active material.Fatty acid, oleic acid, linoleic acid in egg oil have hydrophobicity, can completely cut off external irritant, mitigation office
Portion's pain；Containing a large amount of fat and protein, there are good nutrition and protective effect to the surface of a wound, the logical of capillary can be reduced
Permeability promotes tissue growth, has the function of restraining and inhibiting bacterial growth well.
One of lipid cholesterol structure is similar between phytosterol and Skin Cell, can strengthen skin barrier, to protect
Skin is not affected by.Phytosterol isostearate can largely reduce the transepidermal water loss rate of skin,
All there is splendid repair to epidermis and corium, promote skin metabolism, inhibit scytitis.
Proteoglycan is one of the biological component in the tissue such as the brain for being present in people, bone, muscle, blood vessel, especially
Contain this substance in skin and cartilage more.As one kind of extracellular matrix, cooperateed with ingredients such as collagen, hyaluronic acids
Keep intercellular moisture content.Proteoglycan can accelerate cell Proliferation, moreover it is possible to the environment for being easy proliferation is established for cell.
The chitosan group of chitosan list succinamide have good biocompatibility, adhesion,
Degradability, biocidal property and plasticity, can promote wound healing and regeneration, and outstanding film forming provides excellent moisturizing effect
Fruit.
Summary of the invention
The purpose of the present invention is to provide a kind of skin cream of opponent's foot chapped skin repair function, to solve due to winter
Temperature is low, be air-dried, smegma reduces the problems such as causing trick chapped skin.
A kind of skin cream of opponent's foot chapped skin repair function mainly includes following components and its weight percentage:
Garcinia indica seed rouge 5%-10%, egg oil 3%-8%, phytosterol isostearate 0.5%-2%, soluble protein polysaccharide
0.1%-1%, chitosan list succinamide 0.5%-2.5% synthesize quasi-grease 3%-6%, emulsifier 2%-6%,
Thickener 2%-5%, moisturizer 3%-15%, preservative 0.5%-3%, antioxidant 0.6%-2%, neutralizer 0.1%-
1%, deionized water adds to 100%.
Further, the Garcinia indica seed rouge, egg oil, phytosterol isostearate, soluble protein polysaccharide, de-
The mass ratio of chitosan list succinamide is 10:5:1:0.5:2.
Further, the synthesis quasi-grease is carbonic acid dioctyl ester.Carbonic acid dioctyl ester has excellent spreadability, Ke Yiyou
The spreading property of the improvement skin cream of effect.
Further, the moisturizer is the mixture of glycerol, diglycerol and antierythrite.
Further, the neutralizer is arginine.
Further, the thickener includes oil phase thickeners and water phase thickener, and the oil phase thickeners are that spermaceti is hard
Lipidol, the water phase thickener are carbomer.
Further, the emulsifier is -6 stearate of polyglycereol, Glyceryl stearate citrate, single glyceryl stearate
One or more of acid esters.
Preservative selects one or more of Phenoxyethanol, the smooth caprylate of sorb.
The antioxidant selects tocopherol acetate, pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate).
Preparation to the skin cream of above-mentioned trick chapped skin repair function, mainly comprises the steps that
(1) by Garcinia indica seed rouge, phytosterol isostearate, synthesis quasi-grease, emulsifier, thickener, anti-oxidant
Agent mixing is placed in oily phase pot, and stirring is warming up to 85 DEG C；
(2) deionized water and moisturizer are mixed and is placed in water phase pot, stirring is warming up to 85 DEG C；
(3) it takes the mode vacuumized to be mutually successively pumped into water phase and oil in emulsion pot, opens stirring, mixing speed is
35r/min homogeneous 5 minutes, then keeps the temperature 30 minutes, mixing speed 30r/min；
(4) it is cooled to 60 DEG C, is added egg oil, homogeneous 5 minutes；
(5) 45 DEG C are cooled to, soluble protein polysaccharide, chitosan list succinamide, neutralizer, anti-corrosion is added
Agent continues to stir；
(6) 38 DEG C are cooled to, discharging.
Compared with prior art, the present invention is by Garcinia indica seed rouge, egg oil, phytosterol isostearate, soluble
Proteoglycan, chitosan list succinamide are used cooperatively, and are acted synergistically mutually, and the present invention is by reasonably selecting each group
Divide and its content promotes skin metabolism, inhibits scytitis, can effectively repair with preferable moisturizing and moisture-keeping efficacy
Trick chapped skin does not increase burden to skin and effect is lasting, safe without toxic side effect, and various crowds is suitble to use.
Detailed description of the invention
Fig. 1 is photo before the skin cream using opponent's foot chapped skin repair function of the invention；
Fig. 2 is using the photo after skin cream one month of opponent's foot chapped skin repair function of the invention.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, the present invention is made into one below in conjunction with attached drawing
Step ground detailed description.
Embodiment 1- embodiment 4
Take into account effect, use feeling and its formulation stability, a kind of skin cream of opponent's foot chapped skin repair function, packet
It is as shown in table 1 containing component and its weight percent.
The component and its weight percentage of the skin cream of opponent's foot chapped skin repair function of 1 embodiment 1-4 of table
Preparation method: oil being mixed and is placed in oily phase pot, and stirring is warming up to 85 DEG C；Water phase is mixed and is placed in water phase pot
In, stirring is warming up to 85 DEG C；It takes the mode vacuumized to be mutually successively pumped into water phase and oil in emulsion pot, opens stirring, stirring
Speed is 35r/min, homogeneous 5 minutes, then keeps the temperature 30 minutes, mixing speed 30r/min；60 DEG C are cooled to, yolk is added
Oil, homogeneous 5 minutes；45 DEG C are cooled to, surplus stock is added, continues to stir；38 DEG C are cooled to, is discharged to get the profit is arrived
Skin frost.
Performance of keeping humidity test
Tester 40 are chosen, is randomly divided into 4 groups, every group of 10 people, wherein male 5, female 5, age distribution is 25 to 40
Year, the skin cream of opponent's foot chapped skin repair function of embodiment 1-4 was smeared respectively.Using on the inside of elbow as test when test
Position, it is 2 square centimeters of fixed area as test zone that a size is drawn on the inside of elbow.In 20 DEG C, relative humidity
In 50% indoor environment, with CorneometerCM820 moisture of skin measuring instrument to every group of tester's elbow inside skin
Carry out skin water content test, result by setting humidity measurements (Moisture Measurement Value,
MMV it) indicates, to evaluate the replenishing water and preserving moisture performance of the product, is averaged.The results are shown in Table 2.
Wherein: MMV1 --- the skin MMV value before smearing skin cream, MMV2 --- the skin after smearing skin cream in 1 minute
Skin MMV value, MMV3 --- skin MMV value after smearing skin cream 1 hour.
Make-up water percentage=MMV2/MMV1 × 100%
Moisturizing rate=MMV3/MMV2 × 100%
The performance of keeping humidity of the skin cream of opponent's foot chapped skin repair function of 2 embodiment 1-4 of table is tested
| MMV1 | MMV2 | MMV3 | Make-up water percentage, % | Moisturizing rate, % | |
| Embodiment 1 | 35.6 | 73.7 | 69.8 | 207.0 | 94.7 |
| Embodiment 2 | 35.7 | 71.5 | 66.1 | 200.3 | 92.5 |
| Embodiment 3 | 35.3 | 70.8 | 65.7 | 200.6 | 92.8 |
| Embodiment 4 | 35.4 | 69.2 | 55.5 | 195.5 | 80.2 |
By the test data in table as it can be seen that skin cream of the invention has good moisturizing performance and performance of keeping humidity.Especially
, the data of embodiment 1 are substantially better than embodiment 2-4.The moisturizing of embodiment 4 is largely divided into two aspects, on the one hand as closing
The additive amount of the grease of agent be it is minimum, another side is also minimum, the polysaccharide of effect addition as the amount of the polyalcohol of hygroscopic agent
Moisturizer is also least.
Efficacy assessments
Subject and its method
Subject: random, open, Self-controlled study is taken.Hand and foot chap person 200 are chosen, is randomly divided into 4 groups, often
50 people of group, wherein male 30, female 20, age distribution is 25 to 40 years old.
Application method: embodiment 1-4 skin cream is applied to affected part by patient's clearing skin twice sooner or later daily, and one month
After pay a return visit trial effect.Effect is as shown in table 3.
It cures: indicating that dry skin restores life completely；Skin not re-dry becomes to moisten and smooth；
Effect is preferable: dry skin is greatly improved, and moistens and smoothness makes moderate progress；
Effect is general: dry skin, moist and smoothness make moderate progress, but effect is little.
The trial effect of the skin cream of opponent's foot chapped skin repair function of 3 embodiment 1-4 of table
| Effect | It cures | Effect is preferable | Effect is general |
| Embodiment 1 | 48 | 2 | 0 |
| Embodiment 2 | 44 | 6 | 0 |
| Embodiment 3 | 43 | 6 | 1 |
| Embodiment 4 | 38 | 9 | 3 |
Conclusion: these results suggest that the skin cream has preferable repairing effect to hand and foot chap.
Typical case
Li Lin: female, 39 years old, trick skin was very dry always, winter especially severe, dry using opponent's foot skin skin of the invention
The photo of heel before the skin cream of repair function is split as shown in Figure 1, opponent's foot chapped skin of continuous use embodiment 1 is repaired
Skin cream one month of multiple function, wipes primary sooner or later, and the dry symptom of trick is cured completely, and skin polishes exquisiteness, uses implementation
The photo of one month heel of skin cream of opponent's foot chapped skin repair function of example 1 is as shown in Figure 2.
Comparative example 1-7
A kind of skin cream of opponent's foot chapped skin repair function, comprising component and its weight percent such as shown in table 4.
The component and its weight percentage of the skin cream of opponent's foot chapped skin repair function of 4 comparative example 1-7 of table
Performance of keeping humidity test
Tester 70 are chosen, is randomly divided into 7 groups, every group of 10 people, wherein male 5, female 5, age distribution is 25 to 40
Year, the skin cream of opponent's foot chapped skin repair function of comparative example 1-7 was smeared respectively.Using on the inside of elbow as test when test
Position, it is 2 square centimeters of fixed area as test zone that a size is drawn on the inside of elbow.In 20 DEG C, relative humidity
In 50% indoor environment, with CorneometerCM820 moisture of skin measuring instrument to every group of tester's elbow inside skin
Carry out skin water content test, result by setting humidity measurements (Moisture Measurement Value,
MMV it) indicates, to evaluate the replenishing water and preserving moisture performance of the product, is averaged.
Wherein: MMV1 --- the skin MMV value before smearing skin cream, MMV2 --- the skin after smearing skin cream in 1 minute
Skin MMV value, MMV3 --- skin MMV value after smearing skin cream 1 hour.
Make-up water percentage=MMV2/MMV1 × 100%
Moisturizing rate=MMV3/MMV2 × 100%
The performance of keeping humidity of the skin cream of opponent's foot chapped skin repair function of 5 comparative example 1-7 of table is tested
| MMV1 | MMV2 | MMV3 | Make-up water percentage, % | Moisturizing rate, % | |
| Comparative example 1 | 35.7 | 64.6 | 45.3 | 181.0 | 70.1 |
| Comparative example 2 | 35.3 | 65.1 | 48.6 | 184.4 | 74.7 |
| Comparative example 3 | 35.5 | 66.4 | 53.5 | 187.0 | 80.6 |
| Comparative example 4 | 35.6 | 65.8 | 45.8 | 184.8 | 69.6 |
| Comparative example 5 | 35.4 | 66.3 | 46.1 | 187.3 | 69.5 |
| Comparative example 6 | 35.4 | 71.0 | 66.1 | 200.6 | 93.1 |
| Comparative example 7 | 35.6 | 72.3 | 66.4 | 203.1 | 91.8 |
Efficacy assessments
Subject and its method
Subject: random, open, Self-controlled study is taken.Hand and foot chap person 140 are chosen, is randomly divided into 7 groups, often
20 people of group, wherein male 10, female 10, age distribution is 25 to 40 years old.
Application method: comparative example 1-7 skin cream is applied to affected part by patient's clearing skin twice sooner or later daily, and one month
After pay a return visit trial effect.Effect is as shown in table 6.
It cures: indicating that dry skin restores life completely；Skin not re-dry becomes to moisten and smooth；
Effect is preferable: dry skin is greatly improved, and moistens and smoothness makes moderate progress；
Effect is general: dry skin, moist and smoothness make moderate progress, but effect is little；
The trial effect of the skin cream of opponent's foot chapped skin repair function of 6 comparative example 1-7 of table
| Effect | It cures | Effect is preferable | Effect is general |
| Comparative example 1 | 3 | 7 | 10 |
| Comparative example 2 | 4 | 8 | 8 |
| Comparative example 3 | 5 | 10 | 5 |
| Comparative example 4 | 3 | 5 | 12 |
| Comparative example 5 | 2 | 9 | 9 |
| Comparative example 6 | 18 | 2 | 0 |
| Comparative example 7 | 17 | 2 | 1 |
Skin roughness and its flexibility test
220 hand and foot chap persons are selected, 25~55 years old, are randomly divided into 11 groups, every group of 20 people, continuous use is implemented respectively
Example 1-4, the resulting opponent's foot chapped skin repair function of comparative example 1-7 skin cream 1 month laggard heel of traveling far and wide skin it is thick
Rugosity and its flexibility test, are averaged, and test result is as shown in table 7.
The skin cream skin roughness and its flexibility test effect of 7 embodiment 1-4 of table, comparative example 1-7
Sense organ and physical and chemical index measurement result
Sense organ and physical and chemical index measurement result, as shown in table 8.
8 sense organ of table and physical and chemical index measurement result
The above embodiment of the present invention is only used for that the present invention will be described, does not constitute to embodiments of the present invention
Limitation, those skilled in the art carry out same changes or modifications change, within the scope of the invention as claimed.
Claims (10)
1. a kind of skin cream of opponent's foot chapped skin repair function, which is characterized in that mainly include following components and its weight
Percentage composition: Garcinia indica seed rouge 5%-10%, egg oil 3%-8%, phytosterol isostearate 0.5%-2% are solvable
Property proteoglycan 0.1%-1%, chitosan list succinamide 0.5%-2.5%, synthesize quasi-grease 3%-6%, emulsification
Agent 2%-6%, thickener 2%-5%, moisturizer 3%-15%, preservative 0.6%-3%, antioxidant 0.5%-2% are neutralized
Agent 0.1%-1%, deionized water add to 100%.
2. the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that the Garcinia indica
Seed rouge, egg oil, phytosterol isostearate, soluble protein polysaccharide, chitosan list succinamide mass ratio
For 10:5:1:0.5:2.
3. the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that the synthesis class oil
Rouge is carbonic acid dioctyl ester.
4. the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that the emulsifier is
One or more of -6 stearate of polyglycereol, Glyceryl stearate citrate, single stearine.
5. the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that the thickener packet
Oil phase thickeners and water phase thickener are included, the oil phase thickeners are cetostearyl alcohol, and the water phase thickener is carbomer.
6. the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that the moisturizer is
The mixture of glycerol, diglycerol and antierythrite.
7. the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that the preservative is
One or more of smooth caprylate of Phenoxyethanol, sorb.
8. the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that the antioxidant
For tocopherol acetate, pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate).
9. the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that the neutralizer is
Arginine.
10. the preparation of the skin cream of opponent's foot chapped skin repair function according to claim 1, which is characterized in that main
The following steps are included:
(1) by Garcinia indica seed rouge, phytosterol isostearate, synthesis quasi-grease, emulsifier, oil phase thickeners, anti-oxidant
Agent mixing is placed in oily phase pot, and stirring is warming up to 85 DEG C；
(2) deionized water, water phase thickener and moisturizer are mixed and is placed in water phase pot, stirring is warming up to 85 DEG C；
(3) it takes the mode vacuumized to be successively mutually pumped into water phase in emulsion pot with oil, opens stirring, mixing speed 35r/
Min homogeneous 5 minutes, then keeps the temperature 30 minutes, mixing speed 30r/min；
(4) it is cooled to 60 DEG C, is added egg oil, homogeneous 5 minutes；
(5) 45 DEG C are cooled to, soluble protein polysaccharide, chitosan list succinamide, neutralizer, preservative is added, after
Continuous stirring；
(6) 38 DEG C are cooled to, discharging.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910222968.1A CN109939025A (en) | 2019-03-22 | 2019-03-22 | A kind of skin cream of opponent's foot chapped skin repair function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910222968.1A CN109939025A (en) | 2019-03-22 | 2019-03-22 | A kind of skin cream of opponent's foot chapped skin repair function |
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| CN109939025A true CN109939025A (en) | 2019-06-28 |
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| CN201910222968.1A Pending CN109939025A (en) | 2019-03-22 | 2019-03-22 | A kind of skin cream of opponent's foot chapped skin repair function |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110192997A (en) * | 2019-07-08 | 2019-09-03 | 杭州悦萱堂化妆品有限公司 | A kind of shin moisturizer and preparation method thereof |
| CN110192988A (en) * | 2019-07-08 | 2019-09-03 | 杭州悦萱堂化妆品有限公司 | A kind of face cream and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106551856A (en) * | 2015-09-20 | 2017-04-05 | 沈阳市坤美惜美容用品有限公司 | One kind treats rhagadia manus et pedis cosmetics and preparation method thereof |
| CN108652994A (en) * | 2018-08-03 | 2018-10-16 | 广东丸美生物技术股份有限公司 | A kind of skin matrix and its preparation method and application with moisturizing, improvement wrinkle and anti-oxidation efficacy |
| CN109331095A (en) * | 2018-10-31 | 2019-02-15 | 广州艾蓓生物科技有限公司 | A kind of clearing damp rash composition and preparation method thereof |
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2019
- 2019-03-22 CN CN201910222968.1A patent/CN109939025A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106551856A (en) * | 2015-09-20 | 2017-04-05 | 沈阳市坤美惜美容用品有限公司 | One kind treats rhagadia manus et pedis cosmetics and preparation method thereof |
| CN108652994A (en) * | 2018-08-03 | 2018-10-16 | 广东丸美生物技术股份有限公司 | A kind of skin matrix and its preparation method and application with moisturizing, improvement wrinkle and anti-oxidation efficacy |
| CN109331095A (en) * | 2018-10-31 | 2019-02-15 | 广州艾蓓生物科技有限公司 | A kind of clearing damp rash composition and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110192997A (en) * | 2019-07-08 | 2019-09-03 | 杭州悦萱堂化妆品有限公司 | A kind of shin moisturizer and preparation method thereof |
| CN110192988A (en) * | 2019-07-08 | 2019-09-03 | 杭州悦萱堂化妆品有限公司 | A kind of face cream and preparation method thereof |
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