CN109907174A - Ruminant functional additive - Google Patents
Ruminant functional additive Download PDFInfo
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- CN109907174A CN109907174A CN201910244514.4A CN201910244514A CN109907174A CN 109907174 A CN109907174 A CN 109907174A CN 201910244514 A CN201910244514 A CN 201910244514A CN 109907174 A CN109907174 A CN 109907174A
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- growth
- animal
- ruminant
- vitamin
- carnitine
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- 241000282849 Ruminantia Species 0.000 title claims abstract description 38
- 239000013538 functional additive Substances 0.000 title claims abstract description 10
- 239000011782 vitamin Substances 0.000 claims abstract description 29
- BPMFZUMJYQTVII-UHFFFAOYSA-N guanidinoacetic acid Chemical compound NC(=N)NCC(O)=O BPMFZUMJYQTVII-UHFFFAOYSA-N 0.000 claims abstract description 24
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims abstract description 22
- 229940088594 vitamin Drugs 0.000 claims abstract description 20
- 229930003231 vitamin Natural products 0.000 claims abstract description 20
- 235000013343 vitamin Nutrition 0.000 claims abstract description 20
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract description 20
- 239000000203 mixture Substances 0.000 claims abstract description 16
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229960003151 mercaptamine Drugs 0.000 claims abstract description 14
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 20
- 230000000996 additive effect Effects 0.000 claims description 11
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 10
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 10
- 239000000654 additive Substances 0.000 claims description 10
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 10
- 235000019155 vitamin A Nutrition 0.000 claims description 10
- 239000011719 vitamin A Substances 0.000 claims description 10
- 229940045997 vitamin a Drugs 0.000 claims description 10
- WIGIZIANZCJQQY-UHFFFAOYSA-N 4-ethyl-3-methyl-N-[2-[4-[[[(4-methylcyclohexyl)amino]-oxomethyl]sulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide Chemical compound O=C1C(CC)=C(C)CN1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCC(C)CC2)C=C1 WIGIZIANZCJQQY-UHFFFAOYSA-N 0.000 claims description 9
- 229930003427 Vitamin E Natural products 0.000 claims description 9
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 9
- 235000019165 vitamin E Nutrition 0.000 claims description 9
- 239000011709 vitamin E Substances 0.000 claims description 9
- 229940046009 vitamin E Drugs 0.000 claims description 9
- 241001465754 Metazoa Species 0.000 abstract description 37
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- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 12
- 229910052698 phosphorus Inorganic materials 0.000 description 12
- 239000011574 phosphorus Substances 0.000 description 12
- 229960004203 carnitine Drugs 0.000 description 11
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 9
- 241000283690 Bos taurus Species 0.000 description 9
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 9
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
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- 108010011619 6-Phytase Proteins 0.000 description 4
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 description 4
- DRBBFCLWYRJSJZ-UHFFFAOYSA-N N-phosphocreatine Chemical compound OC(=O)CN(C)C(=N)NP(O)(O)=O DRBBFCLWYRJSJZ-UHFFFAOYSA-N 0.000 description 4
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- 230000029087 digestion Effects 0.000 description 4
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 description 4
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- 241000287828 Gallus gallus Species 0.000 description 3
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- MXNRLFUSFKVQSK-QMMMGPOBSA-O N(6),N(6),N(6)-trimethyl-L-lysine Chemical compound C[N+](C)(C)CCCC[C@H]([NH3+])C([O-])=O MXNRLFUSFKVQSK-QMMMGPOBSA-O 0.000 description 2
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- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 1
- OIRDTQYFTABQOQ-KQYNXXCUSA-N Adenosine Natural products C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 1
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- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
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Landscapes
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Abstract
The invention discloses ruminant functional additive, the vitamin mixtures of the L-carnitine of cysteamine, 90-115g, the glycocyamine of 375-435g and 85-115g in every 1000g containing 365-425g.The present invention has the advantage that moulding animal shape by glycocyamine and L-carnitine and improving the speed of growth, pass through cysteamine again, after eliminating animal excitation activity, caused nauseous state when Ruminant behavior is carried out at once, and cysteamine itself can eliminate the activity of inhibiting hormone of growth, provide animal body inner growth hormone indirectly, promote growth, and three is by suitably matching, and it is very good to the growth-promoting effect of ruminant;Through properly mixed vitamin, under conditions of guaranteeing low in cost, moreover it is possible to guarantee growth of animal needs, animal guarantees animal crust, bone and internal liver health development in fast-growth.
Description
Technical field
The present invention relates to animals to assist foodstuff, is related specifically to the additive of animal feed, and in particular to ruminant function
It can property additive.
Background technique
Ruminant is a suborder in Artiodactyla.It ruminates and refers to that feed will partly disappear under one's belt after after a period of time
The food return of change is chewed again in the mouth, and ruminant is exactly the animal for ruminating this digestion method.Usually some food grass
Animal, because the fiber of plant is more heavy.Ruminant feeding is general relatively more hasty, especially roughage, big portion
Divide and just swallow without sufficiently chewing into cud, after rumen bypass impregnates and softens a period of time, food passes through inverse vomit and comes back to
Oral cavity is mixed into saliva again and swallows the process into cud again by chewing again.In addition to camel and vigone, these animals
All without upper front tooth, but hard gums is had on a corresponding position, for the thing for supporting lower front tooth to be baited.
Ruminant is high to the utilization rate of feed crude fibre especially cellulose and hemicellulose.Ruminant tumor gastric is
One big fermentor, energy decomposition of cellulose, hemicellulose etc. generate volatile fatty acid and utilize.Therefore, forage grass, crops pair
The utilization rate of the high feed of the crude fiber contents such as product and grain and oil processed side product and forage grass, energy is much higher than nonruminant,
And often use the capacity usage ratio of grain trough not as good as nonruminant the nonruminants such as corn.Wheat bran ruminant metabolic energy
It is the 86% of 2770 Mcal/kg of corn for 2370Mcal/kg;And the metabolic energy of chicken only has 1570 Mcal/kg, is corn
The 49% of 3220Mcal/kg;Ruminant only has the 86% of chicken to the utilization rate of corn energy.This is that we develop plant-eating animal
Basic point of departure, if excessively relying on cereal, the sheep raising such as corn just loses meaning.Wheat bran is on the high side currently on the market,
The 80% of general slightly above corn, it is really uneconomical for preparing monogastric animal feed but quite different for ruminant, not counting
The albumen being higher by maintains an equal level or even slightly higher compared with corn benefit.The health of ruminant is cud health first, and cud is strong
The basic guarantee of health is exactly a large amount of crude fibre, therefore it is still necessary to selecting wheat bran under current price.Ruminant is to thick
The utilization of albumen is also different from pig, chicken.It (1) can be by rumen microorganism for synthesizing thallus egg into the nonprotein nitrogen of cud
It is white;(2) it is decomposed into most albumen of cud by rumen microorganism, then synthesising thalli protein, the micro- life of a portion
Object is eaten by cud infusorian and is converted into polypide albumen;(3) finally, microorganism, infusorian and undigested albumen together into
Enter abomasum, then carries out the digestion and absorption process similar to nonruminant.So ruminant to inferior quality, contain more non-egg
The utilization rate of the protein feed of white nitrogen and the crude protein in other low-quality feeds is also above nonruminant, such as DDGS, Cottonseed Meal, beans
Rotten slag, wheat bran etc., and the utilization rate of high-quality protein feed such as dregs of beans is lower than nonruminant, therefore need to often carry out rumen bypass processing
To increase operation rate.Ruminant can utilize phytate phosphorus.Vegetable seeds is stored phosphorus in the form of phytic acid, but animal cannot
Phytase is generated, nonruminant cannot utilize phytate phosphorus, but the microorganism in ruminant tumor gastric can generate phytase, because
And ruminant can utilize phytate phosphorus.Studies have shown that ruminant to the utilization rate of phytate phosphorus 50% or more, adult is ruminated dynamic
Object even up to 90%.There are wheat bran, rice bran, cotton dregs etc., the phytate phosphorus of wheat containing phytic acid (phytate) higher common feedstuffs
Also it is much higher than corn.It is not required to add other phosphorus sources again if preparing ruminant if with these feeds, can also make sometimes
At high phosphorus low calcium, lead to fibrous osteodystrophy.This is also the Important cause of disease of the urolithiasis of ruminant.Present commodity phytic acid
Enzyme product comparative maturity is Phytase, is used for simple stomach homeothermal animal.Its efficiency is real in vitro also not as good as rumen microorganism
It is 30% or more that it is small, which to test condition,.Theoretically, a possibility that whether there is additive effect with rumen microorganism is also little.So
It is not recommended that adding phytase in ruminant.
Today's society is raised for that can add feed addictive in feed in the feed of animal to reach reinforcing basis
Material nutrient value, improves breeding performonce fo animals, guarantees animal health, saves feed cost, improves the effect of livestock products quality.But
It is the feed addictive not dedicated for ruminant, or is used for the feed addictive of ruminant at this stage, to ruminates
Animal is ineffective, causes ruminant slow growth, lean meat percentage lower.
Summary of the invention
The purpose of the present invention is to provide a kind of ruminant functional additives, to solve existing ruminant growth
Slowly, the low problem of lean meat percentage.
To achieve the above object, the technical scheme is that ruminant functional additive, contain in every 1000g
The vitamin mixing of the cysteamine of 365-425g, the L-carnitine of 90-115g, the glycocyamine of 375-435g and 85-115g
Object.
The glycocyamine and 100g of cysteamine containing 400g, the L-carnitine of 100g, 400g in every 1000g
Vitamin mixtures.
The vitamin mixtures include that the dimension of the vitamin A of 20-30g, the vitamine D3 of 10-15g and 55-68g is raw
Plain E.
The vitamin mixtures include the vitamin E of the vitamin A of 25g, the vitamine D3 of 12g and 63g.
In mentioned component, glycocyamine is huge using extensively, acting in animal feed, mainly has:
1, improve animal figure: phosphocreatine only largely exists in muscle, nerve fiber, and content is little in adipose tissue, therefore
Energy can be promoted to shift into musculature.2, promote growth: glycocyamine is the precursor of creatine, and performance is stablized, and is absorbed
Rate is high, and energy can be promoted more to be assigned to the synthesis of musculature.3, product is stablized using safe: glycocyamine is finally with flesh
Ammonia anhydride form is external out by animal organism metabolism, noresidue in body, effectively overcomes many forbidden drugs such as clenbuterol hydrochloride
Toxic side effect, safety are good.4, remove free radical, improve yellowish pink: the free radical that creatine supplementation can be reduced mitochondria generates, and
Obtain preferably yellowish pink and meat quality, accelerate the synthesis of the ATP in muscle, reduce animal transport, turn the heat stresses such as group it is anti-
It answers.
Glycocyamine (C3H7N3O2), make body generate a large amount of phosphate group transfer of material (phosphocreatine,
C4H10N3O5P), to provide power for efficient operations such as the tissues such as muscle, brain, sexual gland, promote energy continuously to
It is distributed in musculature.
Glycocyamine has the conversion process of following reaction formula in body:
L-carnitine also has use in animal feed, and main effect is as follows:
1, it participates in the transhipment of long chain fatty acids and betaoxidation, critical function will be grown in the form of acylcarnitine as carrier
Chain fatty is transported in film outside mitochondria, promotes the beta oxidation of fatty acid, reduces the content of serum cholesterol and triglyceride,
Improve body tolerance.The speed of beta oxidation is heavily dependent on available carnitine amount, and the carnitine of high concentration can increase
The oxidation rate of fat, improves the utilization rate of adipose energy.
2, acyl-CoA/CoA ratio in mitochondria is adjusted, the ratio of the CoA of acyl and CoA in mitochondrial matrix will affect
The activity of pyruvate kinase, thus influence being normally carried out for animal energy i (in vivo) metabolism.Research has shown that carnitine has and adjusts line grain
The effect of internal acyl-CoA/CoA ratio.
3, have and be acylated detoxication, some toxic ester acyl CoA can be generated in the metabolism of mitochondrial fatty acid beta oxidation,
Such as propionyl CoA, some key enzyme activities in mitochondrial metabolism can be printed, cause to poison, and carnitine can be in conjunction with these malicious acyls
Carnitine compound is released and is poisoned.
4, to the influence of protein metabolism, carnitine is mainly methionine and trimethyl lysine is Material synthesis, and carnitine closes
Be necessarily dependent upon breaks down proteins at required raw material and lysine and methionine be provided, cell hydrolysis generate in S- adenosine first sulphur ammonia
Under acid effect, trimethyl lysine is converted by lysine methyl in muscle.Therefore, in feed add carnitine can be reduced it is interior
The synthesis of source carnitine reduces the decomposition of vivo protein, plays the effect for saving lysine and albumen propylhomoserin.Carnitine is non-to body
Must amino acid metabolism also have an impact, the storage that can increase body nitrogen is stayed, promote protein precipitation.
5, the digestion power of animal is improved, carnitine can adjust functions of intestines and stomach, promote digestive juice secretion, improve digestive enzyme
Property, to promote animal appetite.
Cysteamine has the function of reducing inhibiting hormone of growth in animal body, to improve animal growth hormone, promotes dynamic
Object body digestion and metabolism promotes growth of animal.
Vitamin E (C29H50O2) is a kind of liposoluble vitamin, and hydrolysate is tocopherol, and tocopherol can promotion property
Hormone secretion plays an important role to the synthesis of hormone.Vitamin E has very strong antioxidation, can prevent vitamin A, dimension life
The oxidation of plain C.
Vitamin A (molecular formula C20H30O) promotes the biosynthesis of protein and the differentiation of osteocyte.Vitamin A helps
In cell Proliferation and growth.
Vitamine D3 has following physiological function: 1, improving absorption of the human body to calcium, phosphorus, make the level of plasma calcium and blood plasma phosphorus
Reach degree of saturation.2, promote growth and bone calcification, promote tooth sound;3, increase the absorption of phosphorus by intestinal wall, and pass through
The re-absorption of renal tubule increase phosphorus;4, the normal level of citrate in blood is maintained;5, prevent amino acid from damaging by kidney
It loses.
The present invention has the advantage that animal shape is moulded by glycocyamine and L-carnitine and improves the speed of growth,
Again by cysteamine, after eliminating animal excitation activity, caused nauseous state when Ruminant behavior, and cysteamine sheet are carried out at once
Body can eliminate the activity of inhibiting hormone of growth, provide animal body inner growth hormone indirectly, promote growth, and three passes through conjunction
Suitable proportion is very good to the growth-promoting effect of ruminant;It is low-cost in guarantee by properly mixed vitamin
Under the conditions of, moreover it is possible to guarantee growth of animal needs, animal guarantees animal crust, bone and internal liver health in fast-growth
Development;This product promotes speed to the growth of ruminant and reaches 30%-40%, and the lean meat percentage of animal has and significantly mentions
It is high.
Specific embodiment
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
Embodiment 1
Ruminant functional additive, the guanidine radicals second of the cysteamine containing 365g, the L-carnitine of 90g, 435g in every 1000g
The vitamin mixtures of acid and 110g.
The vitamin mixtures include the vitamin E of the vitamin A of 30g, the vitamine D3 of 12g and 68g.
Embodiment 2
Ruminant functional additive, the guanidine radicals of the cysteamine containing 425g, the L-carnitine of 115g, 375g in every 1000g
The vitamin mixtures of acetic acid and 85g.
The vitamin mixtures include the vitamin E of the vitamin A of 20g, the vitamine D3 of 10g and 55g.
Embodiment 3
Ruminant functional additive, the guanidine radicals of the cysteamine containing 400g, the L-carnitine of 100g, 400g in every 1000g
The vitamin mixtures of acetic acid and 100g.
The vitamin mixtures include the vitamin E of the vitamin A of 25g, the vitamine D3 of 12g and 63g.
Embodiment 4
Ruminant functional additive, the guanidine radicals of the cysteamine containing 390g, the L-carnitine of 110g, 415g in every 1000g
The vitamin mixtures of acetic acid and 90g.
The vitamin mixtures include the vitamin E of the vitamin A of 20g, the vitamine D3 of 15g and 55g.
The present invention carries out growth experiment using the Xia Luolai beef cattle at 50 6 monthly ages, and beef cattle is randomly divided into 5 groups, first group
The additive of embodiment 1 is added in feed, is named as experimental group one;The additive of second group of addition embodiment 2 in feed,
It is named as experimental group two;The additive of embodiment 3 is added in third group in feed, is named as experimental group three;4th group in feed
The interior additive that embodiment 4 is added, is named as experimental group four, and the feed of last group is added without additive, is named as control group,
Weigh daily to beef cattle, continue 6 months, measure the daily gain (unit K G) of beef cattle the result is as follows:
Group | 7 monthly ages | August age | September age | 10 monthly ages | 11 monthly ages | 12 monthly ages |
Experimental group one | 1.84 | 1.91 | 1.97 | 2.05 | 2.11 | 2.19 |
Experimental group two | 1.82 | 1.90 | 1.97 | 2.04 | 2.10 | 2.18 |
Experimental group three | 1.88 | 1.93 | 2.01 | 2.08 | 2.15 | 2.23 |
Experimental group four | 1.85 | 1.91 | 1.98 | 2.05 | 2.11 | 2.18 |
Control group | 1.39 | 1.43 | 1.47 | 1.51 | 1.56 | 1.62 |
Experimental result: by the way that the present invention is added, so that the Daily gain of beef cattle is significantly improved, the speed of growth reaches 30%-
40%.Especially experimental group three, the formula used promote most preferably the speed of growth of beef cattle, are optimum proportioning of the invention.
The beef cattle of experimental group one, two, three, four checks all beef cattles after 12 monthly ages delivered for sale, four groups of experimental group meat
Ox ketoboidies lean meat percentage respectively reaches 86%, 87%, 89% and 87%.The lean meat percentage tool of beef cattle increases significantly.
Claims (4)
1. ruminant functional additive, which is characterized in that cysteamine, 90-115g in every 1000g containing 365-425g
The vitamin mixtures of L-carnitine, the glycocyamine of 375-435g and 85-115g.
2. additive as described in claim 1, which is characterized in that the cysteamine containing 400g, 100g in every 1000g
L-carnitine, the glycocyamine of 400g and the vitamin mixtures of 100g.
3. additive as claimed in claim 1 or 2, which is characterized in that the vitamin mixtures include the dimension of 20-30g
The raw element vitamine D3 of A, 10-15g and the vitamin E of 55-68g.
4. additive as claimed in claim 3, which is characterized in that the vitamin mixtures include 25g vitamin A,
The vitamine D3 of 12g and the vitamin E of 63g.
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