CN106889317A - A kind of young age ruminant early weaning accelerator and its feeding method - Google Patents
A kind of young age ruminant early weaning accelerator and its feeding method Download PDFInfo
- Publication number
- CN106889317A CN106889317A CN201710093776.6A CN201710093776A CN106889317A CN 106889317 A CN106889317 A CN 106889317A CN 201710093776 A CN201710093776 A CN 201710093776A CN 106889317 A CN106889317 A CN 106889317A
- Authority
- CN
- China
- Prior art keywords
- accelerator
- young age
- early weaning
- fine fodder
- ruminant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000282849 Ruminantia Species 0.000 title claims abstract description 21
- 238000000034 method Methods 0.000 title claims abstract description 12
- 210000004767 rumen Anatomy 0.000 claims abstract description 28
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 26
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 claims abstract description 22
- 229930182817 methionine Natural products 0.000 claims abstract description 16
- 235000006109 methionine Nutrition 0.000 claims abstract description 16
- 239000004470 DL Methionine Substances 0.000 claims abstract description 14
- FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 13
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 13
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 13
- 229940046009 vitamin E Drugs 0.000 claims abstract description 13
- 239000011709 vitamin E Substances 0.000 claims abstract description 13
- 235000010388 propyl gallate Nutrition 0.000 claims abstract description 8
- 239000000473 propyl gallate Substances 0.000 claims abstract description 8
- 229940075579 propyl gallate Drugs 0.000 claims abstract description 8
- 244000309466 calf Species 0.000 claims description 35
- 230000003078 antioxidant effect Effects 0.000 claims description 19
- 239000003963 antioxidant agent Substances 0.000 claims description 15
- 235000006708 antioxidants Nutrition 0.000 claims description 15
- AZJQQNWSSLCLJN-UHFFFAOYSA-N 2-ethoxyquinoline Chemical compound C1=CC=CC2=NC(OCC)=CC=C21 AZJQQNWSSLCLJN-UHFFFAOYSA-N 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 5
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 4
- 235000013601 eggs Nutrition 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 3
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 claims description 2
- 235000019764 Soybean Meal Nutrition 0.000 claims description 2
- 240000008042 Zea mays Species 0.000 claims description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 2
- 241000482268 Zea mays subsp. mays Species 0.000 claims description 2
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims description 2
- 235000005822 corn Nutrition 0.000 claims description 2
- 235000019700 dicalcium phosphate Nutrition 0.000 claims description 2
- 235000013312 flour Nutrition 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 239000004455 soybean meal Substances 0.000 claims description 2
- 239000004575 stone Substances 0.000 claims description 2
- 235000015099 wheat brans Nutrition 0.000 claims description 2
- 241001465754 Metazoa Species 0.000 abstract description 12
- 230000003647 oxidation Effects 0.000 abstract description 10
- 238000007254 oxidation reaction Methods 0.000 abstract description 10
- 206010012735 Diarrhoea Diseases 0.000 abstract description 8
- 150000002978 peroxides Chemical class 0.000 abstract description 8
- 238000011161 development Methods 0.000 abstract description 4
- 230000006641 stabilisation Effects 0.000 abstract description 3
- 238000011105 stabilization Methods 0.000 abstract description 3
- 206010067484 Adverse reaction Diseases 0.000 abstract description 2
- 230000006838 adverse reaction Effects 0.000 abstract description 2
- 210000000981 epithelium Anatomy 0.000 abstract description 2
- 241000283690 Bos taurus Species 0.000 description 23
- 235000015278 beef Nutrition 0.000 description 20
- 210000004369 blood Anatomy 0.000 description 13
- 239000008280 blood Substances 0.000 description 13
- 238000002474 experimental method Methods 0.000 description 12
- 238000012360 testing method Methods 0.000 description 12
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
- 230000035882 stress Effects 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 235000021050 feed intake Nutrition 0.000 description 8
- 102000019197 Superoxide Dismutase Human genes 0.000 description 7
- 108010012715 Superoxide dismutase Proteins 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 239000003795 chemical substances by application Substances 0.000 description 6
- 235000013384 milk substitute Nutrition 0.000 description 6
- 244000025254 Cannabis sativa Species 0.000 description 5
- 239000004459 forage Substances 0.000 description 5
- 235000013336 milk Nutrition 0.000 description 5
- 239000008267 milk Substances 0.000 description 5
- 210000004080 milk Anatomy 0.000 description 5
- 229910052757 nitrogen Inorganic materials 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- 108010088751 Albumins Proteins 0.000 description 4
- 102000009027 Albumins Human genes 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- 230000003064 anti-oxidating effect Effects 0.000 description 4
- 230000037396 body weight Effects 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 230000002708 enhancing effect Effects 0.000 description 4
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 4
- 210000004209 hair Anatomy 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 229910021645 metal ion Inorganic materials 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- 150000007524 organic acids Chemical class 0.000 description 4
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Substances [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 description 4
- 230000002195 synergetic effect Effects 0.000 description 4
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 235000020256 human milk Nutrition 0.000 description 3
- 210000004251 human milk Anatomy 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 230000036542 oxidative stress Effects 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 3
- 235000019345 sodium thiosulphate Nutrition 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 229940074391 gallic acid Drugs 0.000 description 2
- 235000004515 gallic acid Nutrition 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 231100000989 no adverse effect Toxicity 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 238000005502 peroxidation Methods 0.000 description 2
- 238000003044 randomized block design Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 238000004448 titration Methods 0.000 description 2
- 230000003442 weekly effect Effects 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 206010053759 Growth retardation Diseases 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- VIWKRRWWEWJHBP-UHFFFAOYSA-N acetic acid 2,2,4-trimethylpentane Chemical compound CC(O)=O.CC(C)CC(C)(C)C VIWKRRWWEWJHBP-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000003026 anti-oxygenic effect Effects 0.000 description 1
- 230000002180 anti-stress Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000005784 autoimmunity Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000013401 experimental design Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000019261 food antioxidant Nutrition 0.000 description 1
- 231100000001 growth retardation Toxicity 0.000 description 1
- 230000037111 immune power Effects 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000008557 oxygen metabolism Effects 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/02—Breeding vertebrates
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a kind of feed addictive, more particularly to a kind of young age ruminant early weaning accelerator and its feeding method.A kind of young age ruminant early weaning accelerator, is counted with fine fodder weight to be added as 100%, and the accelerator includes following components:Vitamin E 0.003 0.02%;Ethoxyquinoline 0.006 0.03%;Propylgallate 0.0005 0.005%;Rumen bypass DL methionine 0.05 0.5%.The TAC of animal can be increased using this accelerator, reduce the generation of peroxide, make young age ruminant preferably resist wean brought stress, particularly adverse reaction caused by free-radical oxidation, the pH value of stabilization Rumen Internal Environment is 6.4 6.6, the development of cud epithelium can be conducive to, the generation 10 30% of diarrhoea is reduced.
Description
Technical field
The present invention relates to a kind of feed addictive, more particularly to a kind of young age ruminant early weaning accelerator and its feeding
The method of feeding.
Background technology
During calf wean, along with the change of feed shape, nutriment source and feeding environment, calf is caused
Certain stress reaction.Digestive system, immune organ of early weaning calf etc. are not all developed also completely, and function is not still complete
It is kind, the symptoms of stress such as growth retardation, diarrhoea are easily produced during weaning.
The fatty height of calf forage, is oxidized easily, and during early weaning body redox equilibrium
It is broken, free radical increases, while oxidation resistance declines, causes serious oxidative stress to produce.Milk cow early weaned technology
Although abroad and Some Domestic large-scale milch cow farms start to carry out, China is still at an early stage, feeding and management level
Do not catch up with the directive breeding needs to cud, to wean during resisting stress intervention techniques be more a lack of research, wean calf is made
Into stress root it is still not very clear.Especially become in wean its digestion characteristics of this, physiochemical indice of calf in special physiological stage
Law and alleviation oxidative stress lack research to the mechanism of action for improving calf antioxidant status, it is necessary to a large amount of basic research
Further improve the Cultivating techniques of calf.
The content of the invention
It is an object of the invention to a kind of young age ruminant early weaning accelerator being added into feed, it can be effective
The inoxidizability of feed is improved, strengthens anti-oxidant animal itself, anti-stress ability and immunocompetence, enhancing rumen microorganism life
It is long.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of young age ruminant early weaning accelerator, is counted with fine fodder weight to be added as 100%, accelerator bag
Include following components:Vitamin E 0.003-0.02%;Ethoxyquinoline 0.006-0.03%;Propylgallate (PG)
0.0005-0.005%;Rumen bypass DL methionine 0.05-0.5%.
Vitamin E can play internal antioxidant and be also required vitamin, be conducive to transferring animal itself
Immunocompetence.PG is strength feed antioxidant, and can prevent VE oxidations and ethoxyquinoline from sharing and can reduce consumption and reach
To more preferable antioxidant effect.Ethoxyquinoline can play the dual antioxidation of in vitro and in vivo.Several materials can be with
There is the synergy of internal antioxidation in vitro, promote the growth of rumen microorganism, improve animal autoimmunity ability.
Rumen bypass DL methionine in formula plays synergistic effect, with chelated metal ions, anti-oxidant and offer organic acid
Supplementary function.And suitable rumen bypass rate ensure that the growth of the microorganism in cud, promote cud development, and supply simultaneously
The methionine for answering animal after cud needs, enhancing animal immunizing power, resisting stress power and methyl supply capacity.
Ethoxyquinoline is one of feed antioxidant of function admirable, is most economical antioxidant, it is adaptable to premix
The product of material, fish meal and addition fat, can prevent vitamin A. D. E therein etc. and the rotten natural pigment oxidation of fatty oxygen from becoming
Color, and have certain mould proof and preservation;Separately can be used as food antioxidant, fruit antistaling agent, rubber antioxidant.In this hair
In bright accelerator, ethoxyquinoline can play a part of in vivo combine in vitro it is anti-oxidant, alleviate stress, cooperateed with vitamin E,
VE can it is anti-oxidant in the cell, alleviate stress;Ethoxyquinoline can play antioxidation in body fluid, and improve animal immune
Power.And can ensure that the unrighted acid on animal erythrocyte film is not oxidized, it is ensured that the stability of biomembrane and flowing
Property, improve the pest resistance of animal.
Preferably, the accelerator includes following components:Vitamin E 0.006-0.01%;Ethoxyquinoline 0.012-
0.024%;Propylgallate (PG) 0.001-0.002%;Rumen bypass DL methionine 0.4-0.5%.
Preferably, the rumen bypass rate of rumen bypass DL methionine is 50-80%.Rumen bypass rate is how many egg is show
Propylhomoserin can be by the index of cud.The methionine that the rumen bypass rate of 50-80% can discharge suitable proportion in cud supplies knurl
The synthesis of stomach microorganism and the effect of the above-mentioned other materials of enhancing.And the rumen bypass egg ammonia of ruminant proper ratio is provided
Acid enhancing animal immunizing power, the free methyl of offer promote animal synthetic phospholipid phatidylcholine, it is ensured that the mobility and stabilization of biomembrane
Property.
A kind of fine fodder composition for young age ruminant early weaning, the fine fodder composition includes fine fodder and promotion
Agent, wherein being counted with fine fodder weight as 100%, the accelerator includes following components:Vitamin E 0.003-0.02%;Ethyoxyl
Quinoline 0.006-0.03%;Propylgallate (PG) 0.0005-0.005%;Rumen bypass DL methionine 0.05-0.5%.
Preferably, described fine fodder includes the raw material of following mass fraction meter:Corn 52.0%, Soybean Meal 27.5%,
Popcorn 5.0%, wheat bran 11.0%, salt 1.0%, calcium monohydrogen phosphate 1.1%, stone flour 1.4%, calf premix 1.0%.
The beneficial effects of the invention are as follows:The wean level of China ruminant is still relatively low, incorrect wean method with
And without the additive for wean cause China cattle and sheep weaning period generally occur it is serious stress phenomenon, feed intake is low
Under, diarrhoea, serious is even dead.Can play nutrient synergistic effect using this accelerator, with chelated metal ions, it is anti-oxidant and
The supplementary function of organic acid is provided, increases the TAC of animal, reduce the generation of peroxide, make young age ruminant
Preferably resistance wean brought stress, particularly adverse reaction caused by free-radical oxidation, improve daily gain, improve wean
Afterwards to the adaptability of daily ration, the pH value of stabilization Rumen Internal Environment can be conducive to the development of cud epithelium in 6.4-6.6, reduce abdomen
The generation 10-30% for rushing down.
Specific embodiment
Below by specific embodiment, technical scheme is described in further detail.It should be appreciated that this hair
Bright implementation is not limited to the following examples, and any formal accommodation and/or change made to the present invention will all fall
Enter the scope of the present invention.
In the present invention, if not refering in particular to, all of part, percentage are unit of weight, equipment and raw material for being used etc.
It is commercially available or commonly used in the art.Method in following embodiments, unless otherwise instructed, is the normal of this area
Rule method.
Rumen bypass DL methionine, purchased from the rumen bypass DL methionine that Hangzhou Kangdequan Feed Co., Ltd, embodiment use
Rumen bypass rate be 50-80%;
Calf premix, my special agricultural science and technology Co., Ltd is thought purchased from Hangzhou;
Love can be more, and Nuo Weisi companies of the U.S., active ingredient is ethoxyquinoline, and the mass fraction of ethoxyquinoline is about
60%.
Embodiment 1:
A kind of early weaning accelerator (hereinafter referred to as combining accelerator), is counted with the fine fodder weight added as 100%,
It is composed of the following components:Vitamin E 0.006%;Love can be more (Nuo Weisi companies of the U.S., active ingredient is ethoxyquinoline)
0.02%;Propylgallate (PG) 0.001%;Rumen bypass DL methionine 0.4%.The accelerator adds when using in fine fodder
Plus.
Embodiment 2:
A kind of early weaning accelerator (hereinafter referred to as combining accelerator), is counted with fine fodder weight as 100%, including:
Vitamin E 0.006%;Love can be more (Nuo Weisi companies of the U.S., active ingredient is ethoxyquinoline) 0.02%;Gallic acid third
Ester (PG) 0.001%;Rumen bypass DL methionine (plays synergistic effect, with chelated metal ions, anti-oxidant and provide organic acid
Supplementary function) 0.4%.The accelerator is added when using in fine fodder.
Embodiment 3:
A kind of early weaning accelerator (hereinafter referred to as combining accelerator), is counted with fine fodder weight as 100%, including:
Vitamin E 0.006%;Love can be more (Nuo Weisi companies of the U.S., active ingredient is ethoxyquinoline) 0.02%;Gallic acid third
Ester (PG) 0.001%;Rumen bypass DL methionine (plays synergistic effect, with chelated metal ions, anti-oxidant and provide organic acid
Supplementary function) 0.4%.The accelerator is added when using in fine fodder.
It is verification the verifying results, feeding experiment is carried out using the obtained joint accelerator of embodiment 1 below:
1. the antioxidant effect of accelerator is combined
Experimental design is control group feed using opened guideway and powered milk substitute 1:1 coordinates, test group using joint accelerator or
Ethoxyquinoline (0.025%) or vitamin E (300mg/kg) are used as treatment group.
Determine antioxidant effect by determining peroxide number (POV).Peroxide number uses active oxygen metabolism (AOM)
Method, determines according to GB GB/T 5538-2005, and its principle is according to generation peroxide and KI during Oxidation of Fat and Oils
Effect, generates free-iodine, is titrated with hypo solution, calculates peroxide number.3g samples are weighed in conical flask, is incited somebody to action
50mL acetic acid-isooctane solution adds sample dissolution in conical flask, adds 0.5mL saturated solution of potassium iodide to make its reaction 1min.
30mL distilled water is added immediately after, titrates above-mentioned solution with hypo solution until yellow almost disappears.Addition 0.5mL
Starch solution continues to be titrated to the blue as titration end-point that disappears.The sodium thiosulfate volume of consumption is recorded, according to following equation
Calculate peroxide number:POV=1000 (V-V0) c/m, wherein, V is the volume (mL) of the hypo solution of titration, and V0 is
The sodium thiosulfate volume (mL) of blank, c is the concentration (mol/L) of sodium thiosulfate, and m is the quality for weighing sample, and unit is
g。
Each treatment group peroxide number of table 1
Feed oxidation deterioration is just illustrated higher than 5.0meq/kg in feedstuff, is added in feed in this research and promoted
Agent, the POV for being surveyed below 5.0meq/kg illustrate that quality of the fodder is good, this with adopted feed normal temperature under time for storing compared with
Short, feed freshness is higher relevant.The POV of addition accelerator each group is below control group in addition, illustrates to add promotion in feed
Agent can play good antioxidant effect.The preventing and treating feed oxide effect of joint accelerator is better than individually as seen from Table 1
Accelerator group.
2. joint accelerator implements time determination
Experiment uses RANDOMIZED BLOCK DESIGN.Selection is grown normally, the southern ox calf that health has just been born without disease
20, according to the principle that body weight, date of birth are same or like, it is randomly assigned into 2 groups:Control group, test group, every group 10
Ox.
The feeding powered milk substitute of calf replaces as breast milk, raises to calf and reaches 45 ages in days or so wean, and opened guideway is placed on feeding
Calf free choice feeding is supplied in grass.
Control group feeds accelerator after wean, and test group starts to feed accelerator for 2 weeks before wean.
The opened guideway (fine fodder) of each group calf is shown in Table 2 in being placed on forage grass for calf free choice feeding, opened guideway (fine fodder) formula.
The opened guideway of table 2 (fine fodder) is formulated
Calf, body chi original body mass, weanling weight and 15 are determined during experiment, 30 days body weight determine weekly feed intake,
Data are shown in Table 3.
Respectively at the 2nd day after wean, the 10th day, the 20th day collection blood sample 10ml, centrifugation packing 3 was managed.For determining serum
Middle SOD (superoxide dismutase), MDA (MDA), TAOC (TAC), glucose, total protein, albumin, urine
Plain nitrogen, data are shown in Table 4.
The different time points of table 3 implement influence of the joint accelerator to Beef Cattle Growth performance
The different time points of table 4 implement influence of the joint accelerator to beef cattle blood
By finding out in table 3, there is no negative effect to beef cattle feed intake using joint is anti-oxidant, 11.8% (P is increased on the contrary
=0.05).The increase of feed intake may improve calf health with accelerator is combined, and alleviate oxidative stress relevant.And join
The implementation for closing accelerator selects start preferably for 2 weeks before wean.
Wean starts the daily gain that joint accelerator improves beef cattle, test group average daily gain control group high for first 2 weeks
5.1%, this explanation, when joint accelerator is used within 2 weeks before wean, can improve the appetite of beef cattle, and to feed conversion rate
Also helpful, this also causes the daily gain of test group beef cattle and weightening feeding than higher than control group.
As shown in table 4, joint accelerator is used after weaning preceding 2 weeks or wean to blood total protein, albumin, the blood of beef cattle
The content of sugar and urea nitrogen has no significant effect (P>0.05).Test group and the blood urea nitrogen (BUN) content difference of control group beef cattle
Do not illustrate significantly to have no adverse effect beef cattle nitrogen metabolism using joint accelerator.In addition, the SOD of the blood of test group beef cattle and
T-AOC will be significantly higher than control group profile and be conducive to improving calf oxidation resistance using joint accelerator before wean.And try
The reduction explanation of group MDA is tested, helps to reduce Peroxidation Product in young calf body using joint accelerator within 2 weeks before wean.
In addition, control group has 3 hairs to give birth to diarrhoea, and test group is not suffered from diarrhoea generation.
Research show that substituting recommendation 2 weeks implementation addition joints before wean when breast milk carries out early weaning using powered milk substitute promotees
Enter agent.
3. joint promotes agent dose to determine
Experiment uses RANDOMIZED BLOCK DESIGN.Selection is grown normally, the southern ox calf that health has just been born without disease
30, according to the principle that body weight, date of birth are same or like, it is randomly assigned into 3 groups:2 groups of control group, 1 group of experiment and experiment,
Every group 10.
The feeding powered milk substitute of calf replaces as breast milk, raises to calf and reaches 45 ages in days or so wean, and opened guideway (be shown in by formula
Table 2) it is placed in forage grass for calf free choice feeding, persistently feed accelerator.
Without accelerator in control group daily ration, powered milk substitute is fed, to 45 ages in days wean (being not added with accelerator).
The joint accelerator of 1 multiple dose in 1 group of daily ration is tested, milk replacer is fed, raised to 45 ages in days, stopped hello powered milk substitute and hold
Since continuous feeding accelerator wean is first 2 weeks 30 days after being fed to wean.
The joint accelerator of 2 multiple doses in 2 groups of daily rations is tested, milk replacer is fed, raised to 45 ages in days, stop feeding milk replacer,
Opened guideway supplies calf free choice feeding in being placed on forage grass, and persistently since feeding EQ wean is first 2 weeks 30 days after being fed to wean.
The opened guideway of each group calf supplies calf free choice feeding in being placed on forage grass.
Calf, body chi original body mass, weanling weight and 15 are determined during experiment, 30 days body weight determine weekly feed intake,
Data are shown in Table 5.
Rumen fluid, Sartorius PB -20 type pH meters are gathered in 1-2 days interior stomach tube sampling apparatuses after experiment calf wean
Determine medium pH value.Before measure, pH meter is first corrected with buffer solution.
Respectively at the 2nd day after wean, the 10th day, the 20th day collection blood sample 10ml, centrifugation packing 3 was managed.For determining serum
Middle SOD (superoxide dismutase), MDA (MDA), TAOC (TAC), glucose, total protein, albumin, urine
Plain nitrogen, data are shown in Table 6.
The various dose of table 5 combines influence of the anti-accelerator to Beef Cattle Growth performance
The different time points of table 6 implement influence of the joint accelerator to beef cattle blood
By finding out in table 5,1 multiple dose joint accelerator improves beef cattle feed intake, but 2 multiple doses joint accelerator with it is right
Acted on compared to no raising according to group.The increase of feed intake may improve calf health with accelerator is combined, and alleviating oxidation should
Swash relevant.And excessive use accelerator may be unfavorable to searching for food.
Wean begins to use joint accelerator or 2 multiple doses joint accelerator to improve the daily gain of beef cattle, examination for first 2 weeks
2 groups higher than control group average daily gain by 17.3% and 7.7% respectively of 1 group of group and experiment are tested, and is increased weight:Feed intake each group does not show
Write difference (P>0.05).This explanation, when weaning first 2 weeks using 1 multiple dose joint accelerator, can improve the appetite of beef cattle, and
Also helpful to feed conversion rate, this also causes the daily gain of test group beef cattle and weightening feeding than higher than control group.And use 2
Effect is not more preferable than 1 multiple dose during multiple dose joint accelerator.The rumen fluid pH value of other each group is not significantly different from, but
It is numerically to be partial to neutrality, is conducive to the development of cud, illustrates to produce lumen fermentation environment using the joint accelerator
Change.
As shown in table 6, blood total egg of the accelerator to beef cattle is combined using 1 times or 2 multiple doses after weaning first 2 weeks or wean
In vain, the content of albumin, blood sugar and urea nitrogen has no significant effect (P>0.05).The blood urine of test group and control group beef cattle
Plain nitrogen content difference does not illustrate significantly to have no adverse effect beef cattle nitrogen metabolism using joint accelerator.1 times or 2 multiple doses joint
The SOD and T-AOC of the blood of accelerator test group beef cattle will be significantly higher than control group profile and joint accelerator is used before wean
Be conducive to improving calf oxidation resistance.And the reduction for testing MDA in 1 group and 2 groups of calf blood of experiment is illustrated, wean first 2 weeks
Help to reduce Peroxidation Product in young calf body using joint accelerator.
Calf is weaned first 2 weeks and combines accelerator compared with 1 times is combined accelerator using 2 multiple doses, and SOD, T-AOC, MDA are equal
It is not significantly different from.This experiment shows, 2 multiple doses joint accelerator does not have and further carried on 1 times is combined accelerator basis
High antioxygenic property.Therefore, joint accelerator need not be higher than 2 multiple doses.
In addition, control group diarrhoea generation has 3,1 times of accelerator group has 1 hair to give birth to diarrhoea, and 2 multiple dose groups do not occur
Diarrhoea situation.
Experiment understands according to more than, and early weaning accelerator of the invention and cultural method are disconnected in young age ruminant
Implementation result preferably, recommends wean to come into effect for first 2 weeks before milk, is capable of achieving preferable inside and outside joint anti-oxidation efficacy, recommends
Dosage is that 1-2 multiple doses combine accelerator.
Embodiment described above is a kind of preferably scheme of the invention, not makees any formal to the present invention
Limitation, also has other variants and remodeling on the premise of without departing from the technical scheme described in claim.
Claims (7)
1. a kind of young age ruminant early weaning accelerator, it is characterised in that:Counted as 100% with fine fodder weight to be added, should
Accelerator includes following components:Vitamin E 0.003-0.02%;Ethoxyquinoline 0.006-0.03%;Propylgallate(PG)
0.0005-0.005%;Rumen bypass DL methionine 0.05-0.5%.
2. young age ruminant early weaning accelerator according to claim 1, it is characterised in that the accelerator include with
Lower component:Vitamin E 0.006-0.01%;Ethoxyquinoline 0.012-0.024%;Propylgallate(PG) 0.001 -
0.002%;Rumen bypass DL methionine 0.4-0.5%.
3. young age ruminant early weaning accelerator according to claim 1, it is characterised in that:The rumen bypass DL eggs
The rumen bypass rate of propylhomoserin is 50-80%.
4. the young age ruminant early weaning accelerator described in a kind of claim 1 is in the anti-oxidant side of young age ruminant feed
The application in face.
5. the feeding method of the young age ruminant early weaning accelerator described in a kind of use claim 1, it is characterised in that:
The accelerator is in the wean of young age ruminant starts added to fine fodder for first 2 weeks.
6. a kind of fine fodder composition for young age ruminant early weaning, it is characterised in that:The fine fodder composition includes essence
Material and accelerator, wherein being counted with fine fodder weight as 100%, the accelerator includes following components:Vitamin E 0.003-0.02%;
Ethoxyquinoline 0.006-0.03%;Propylgallate(PG) 0.0005-0.005%;Rumen bypass DL methionine 0.05-
0.5%。
7. fine fodder composition according to claim 6, it is characterised in that:Described fine fodder includes following mass fraction meter
Raw material:Corn 52.0%, Soybean Meal 27.5%, popcorn 5.0%, wheat bran 11.0%, salt 1.0%, calcium monohydrogen phosphate 1.1%,
Stone flour 1.4%, calf premix 1.0%.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710093776.6A CN106889317B (en) | 2017-02-21 | 2017-02-21 | Early weaning promoter for young ruminants and feeding method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710093776.6A CN106889317B (en) | 2017-02-21 | 2017-02-21 | Early weaning promoter for young ruminants and feeding method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106889317A true CN106889317A (en) | 2017-06-27 |
CN106889317B CN106889317B (en) | 2020-05-22 |
Family
ID=59184833
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710093776.6A Active CN106889317B (en) | 2017-02-21 | 2017-02-21 | Early weaning promoter for young ruminants and feeding method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106889317B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114468150A (en) * | 2022-01-26 | 2022-05-13 | 南京农业大学 | Application of gentisic acid in promoting growth and rumen development of young ruminants |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1795741A (en) * | 2004-12-29 | 2006-07-05 | 上海光明荷斯坦牧业有限公司 | Premix material and proportioned pellet feed for calves in earlier stage and preparation method |
CN101053372A (en) * | 2006-04-14 | 2007-10-17 | 中国农业大学 | Rumen bypass methionine feed for feeding cow and its preparation method and application |
CN101692878A (en) * | 2009-10-23 | 2010-04-14 | 北京九州大地生物技术集团股份有限公司 | Method for preparing antidysenteric early-weaning of calf opening material |
CN103518975A (en) * | 2013-10-23 | 2014-01-22 | 麦仑(漳州)生物科技有限公司 | Compound antioxidant for animal feeds as well as preparation method of compound antioxidant |
CN104222666A (en) * | 2014-09-28 | 2014-12-24 | 四川铁骑力士实业有限公司 | Fully-mixed ration feed capable of reducing weaning stress of lamb |
CN104351542A (en) * | 2014-11-10 | 2015-02-18 | 广东恒兴饲料实业股份有限公司 | Creep feed capable of reducing piglet weanling stress as well as preparation method and application method thereof |
CN106343182A (en) * | 2016-08-12 | 2017-01-25 | 黑龙江八农垦大学 | Feed additive for reducing nitrogen excretion of ruminants and preparation method of feed additive |
-
2017
- 2017-02-21 CN CN201710093776.6A patent/CN106889317B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1795741A (en) * | 2004-12-29 | 2006-07-05 | 上海光明荷斯坦牧业有限公司 | Premix material and proportioned pellet feed for calves in earlier stage and preparation method |
CN101053372A (en) * | 2006-04-14 | 2007-10-17 | 中国农业大学 | Rumen bypass methionine feed for feeding cow and its preparation method and application |
CN101692878A (en) * | 2009-10-23 | 2010-04-14 | 北京九州大地生物技术集团股份有限公司 | Method for preparing antidysenteric early-weaning of calf opening material |
CN103518975A (en) * | 2013-10-23 | 2014-01-22 | 麦仑(漳州)生物科技有限公司 | Compound antioxidant for animal feeds as well as preparation method of compound antioxidant |
CN104222666A (en) * | 2014-09-28 | 2014-12-24 | 四川铁骑力士实业有限公司 | Fully-mixed ration feed capable of reducing weaning stress of lamb |
CN104351542A (en) * | 2014-11-10 | 2015-02-18 | 广东恒兴饲料实业股份有限公司 | Creep feed capable of reducing piglet weanling stress as well as preparation method and application method thereof |
CN106343182A (en) * | 2016-08-12 | 2017-01-25 | 黑龙江八农垦大学 | Feed additive for reducing nitrogen excretion of ruminants and preparation method of feed additive |
Non-Patent Citations (1)
Title |
---|
ÁNGEL ABUELO ET AL: "Effect of colostrum redox balance on the oxidative status of calves during the first 3 months of life and the relationship with passive immune acquisition", 《THE VETERINARY JOURNAL》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114468150A (en) * | 2022-01-26 | 2022-05-13 | 南京农业大学 | Application of gentisic acid in promoting growth and rumen development of young ruminants |
CN114468150B (en) * | 2022-01-26 | 2022-11-25 | 南京农业大学 | Application of gentisic acid in promoting growth and rumen development of young ruminants |
Also Published As
Publication number | Publication date |
---|---|
CN106889317B (en) | 2020-05-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Löfstedt | White muscle disease of foals | |
RU2755947C2 (en) | Animal feed additive and method | |
Hawe et al. | The effects of dietary fibre, lactose and antibiotic on the levels of skatole and indole in faeces and subcutaneous fat in growing pigs | |
Kosiorowska et al. | Gastrointestinal development of dairy calves fed low-or high-starch concentrate at two milk allowances | |
Bell | Ferret nutrition | |
BR112019022345A2 (en) | method for feeding a ruminant calf | |
CN102178051B (en) | Nutrient-functional feed attractant | |
RU2470522C2 (en) | Impact on pigs for fodder assimilation coefficient reduction or growth rate increase | |
CN106889327A (en) | A kind of milk powder for sucking pig and preparation method thereof | |
KR100372341B1 (en) | Carnitine-Supplemented Diets for Gestating and Lactating Swine | |
Wu et al. | Effects of forage type and age at which forage provision is started on growth performance, rumen fermentation, blood metabolites and intestinal enzymes in Holstein calves | |
WO2002071865A1 (en) | Method of feeding a ruminant | |
Prebble | Nutrition and feeding | |
ES2948678T3 (en) | Use of nitrate for the treatment of postpartum dysgalactia syndrome of monogastric mammals | |
CN106889317A (en) | A kind of young age ruminant early weaning accelerator and its feeding method | |
CN109480063A (en) | A kind of biological environmental production type fowl premix | |
CN108617856A (en) | Application of the zinc benzoate in preparing animal feed additive | |
RU2512305C1 (en) | Sapromix vitamin-and-mineral concentrate for farm animals (versions) | |
Tomar et al. | Feeding Management of Ruminant Livestock | |
CN108703268A (en) | A kind of premix and the sow complete feed being configured to using the premix | |
RU2211578C1 (en) | Fodder supplement "kisolan" and method for its feeding | |
WO2007097203A1 (en) | Feed additive | |
Sasidharan et al. | TRANSITION OF DIGESTION IN DAIRY CALVES | |
Stockman et al. | Nutrition for Small Mammalian Companion Herbivores and Carnivores | |
De Passillé et al. | Code of Practice for the Care and Handling of veal Cattle: Review of Scientific Research on Priority Issues |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |