CN109876058A - A kind of pharmaceutical composition and preparation method thereof for treating anaphylactoid purpura - Google Patents
A kind of pharmaceutical composition and preparation method thereof for treating anaphylactoid purpura Download PDFInfo
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- CN109876058A CN109876058A CN201910331182.3A CN201910331182A CN109876058A CN 109876058 A CN109876058 A CN 109876058A CN 201910331182 A CN201910331182 A CN 201910331182A CN 109876058 A CN109876058 A CN 109876058A
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- anaphylactoid purpura
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Abstract
The present invention provides a kind of pharmaceutical compositions and preparation method thereof for treating anaphylactoid purpura, are related to technical field of traditional Chinese medicines.It is a kind of for treating the pharmaceutical composition of anaphylactoid purpura, be mainly made of raw material, according to parts by weight, raw material includes 100~180 parts of ovate neolepisorus herb, 75~120 parts of tea oil.To have the function of clearing heat and detoxicating, antibacterial anti-inflammatory, cooling blood and hemostasis after ovate neolepisorus herb and tea oil compatibility；Anaphylactoid purpura can be effectively treated, and uneasy to recur.A kind of preparation method of aforementioned pharmaceutical compositions mixes ovate neolepisorus herb and tea oil.This method is at low cost, simple and easy, being capable of industrialization large-scale production.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of pharmaceutical composition for treating anaphylactoid purpura and
Preparation method.
Background technique
Anaphylactoid purpura is tiny artery and capillary hemorrhage caused by a kind of vasculitis, is mainly shown as purpura, abdomen
Bitterly, arthralgia and renal damage etc., the cause of disease is more complex, and the allergy object such as pathogenic infection, drug or pollen may cause, 7-14
Year is the disease high-incidence season.
China's treatment anaphylactoid purpura is frequently with antalgesic, solution spasm medicine, antihistamine, anticoagulant medicine etc., Chinese medicine at present
Treatment then mostly uses oral traditional Chinese medicine preparation.After the Western medicine or Chinese materia medica preparation of above-mentioned higher cost, anaphylactoid purpura is still
It is easy recurrence.
Summary of the invention
The purpose of the present invention is to provide a kind of for treating the pharmaceutical composition of anaphylactoid purpura, this pharmaceutical composition energy
Enough sufficiently treatment anaphylactoid purpuras, and the case where be not in recurrence；Cost is relatively low simultaneously.
Another object of the present invention is to provide a kind of for treating the preparation method of the pharmaceutical composition of anaphylactoid purpura,
Preparation method is simple for this, strong operability.
The present invention solves its technical problem and adopts the following technical solutions to realize.
The present invention proposes a kind of for treating the pharmaceutical composition of anaphylactoid purpura, is mainly made of raw material, by weight
Number meter, raw material includes 100~180 parts of ovate neolepisorus herb, 75~120 parts of tea oil.
The present invention propose it is a kind of above-mentioned for treating the preparation method of the pharmaceutical composition of anaphylactoid purpura, by ovate neolepisorus herb and
Tea oil mixing.
A kind of beneficial effect of pharmaceutical composition for treating anaphylactoid purpura proposed by the present invention and preparation method thereof
It is:
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 100~180 parts of ovate neolepisorus herb, 75~120 parts of tea oil.Ovate neolepisorus herb is fern Polypodiaceae shield Cyclosorus plant shield fern also known as west wind
Sword, single leaf fan fern, have the effect of clearing heat and promoting diuresis, cooling blood and hemostasis, can pick herb or leaf uses.Tea oil, by camellia seed pressure
It squeezes and obtains, containing a variety of fatty acid such as oleic acid, linoleic acid, linolenic acids, there is the effect of clearing heat and detoxicating, antibacterial anti-inflammatory.By ovate neolepisorus herb
And have the function of clearing heat and detoxicating, antibacterial anti-inflammatory, cooling blood and hemostasis after tea oil compatibility；Anaphylactoid purpura can be effectively treated, and
It is uneasy to recur.
It is a kind of above-mentioned for treating the preparation method of the pharmaceutical composition of anaphylactoid purpura, ovate neolepisorus herb and tea oil are mixed.
This method is at low cost, simple and easy, being capable of industrialization large-scale production.
Specific embodiment
It in order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below will be in the embodiment of the present invention
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, according to normal conditions or manufacturer builds
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
Below to a kind of pharmaceutical composition for treating anaphylactoid purpura of the embodiment of the present invention and preparation method thereof into
Row illustrates.
The present embodiment it is a kind of for treating the pharmaceutical composition of anaphylactoid purpura, be mainly made of raw material, by weight
Number meter, raw material includes 100~180 parts of ovate neolepisorus herb, 75~120 parts of tea oil.
Ovate neolepisorus herb is that fern Polypodiaceae shield Cyclosorus plant shield fern also known as west wind sword, single leaf fan fern, have clearing heat and promoting diuresis,
The effect of cooling blood and hemostasis, can pick herb or leaf uses.
Tea oil is squeezed by camellia seed and obtain, containing a variety of fatty acid such as oleic acid, linoleic acid, linolenic acid, with it is clearing heat and detoxicating,
The effect of antibacterial anti-inflammatory.
To have the function of clearing heat and detoxicating, antibacterial anti-inflammatory, cooling blood and hemostasis after ovate neolepisorus herb and tea oil compatibility；It can effectively control
Anaphylactoid purpura is treated, and uneasy to recur.
Preferably, raw material includes 120~160 parts of ovate neolepisorus herb, 80~100 parts of tea oil.
It is further preferable that raw material includes 150 parts of ovate neolepisorus herb, 100 parts of tea oil.By inventor's the study found that matching at this
Than under, the effect of the medicine composite for curing anaphylactoid purpura is best.
It should be noted that in the present embodiment, the density of tea oil is 0.8~1.3g/ml.
In preferably a kind of embodiment of the present embodiment, ovate neolepisorus herb selects herb or leaf.
The present embodiment additionally provides a kind of preparation method of above-mentioned pharmaceutical composition for being used to treat anaphylactoid purpura, will be big
Golden knife and tea oil mixing.This method is simple and easy, being capable of industrialization large-scale production.
Preferably, it is mixed again with ovate neolepisorus herb after first heating tea oil.Medicine group can be significantly improved after first tea oil is heated
Close the curative effect of object.
Preferably, tea oil is heated to 50 DEG C~70 DEG C.Within this temperature range, will not destroy in raw material it is effective at
Point, improve drug effect.It is further preferable that tea oil is heated to 60 DEG C.
It is emphasized that in the present embodiment it is preferred to tea oil is heated using the equipment with a thermometer, with stringent
Control the temperature of tea oil.
Preferably, ovate neolepisorus herb is crushed before ovate neolepisorus herb and tea oil are mixed.Preferably, ovate neolepisorus herb is crushed to 60~
100 mesh.First its effective ingredient can be made fully to mix with tea oil ovate neolepisorus herb crushing.
The present embodiment additionally provides a kind of specific treatment method of pharmaceutical composition and step for preferably treating anaphylactoid purpura
Suddenly are as follows:
The first step picks ovate neolepisorus herb herb or leaf, smashs to pieces, wrapped with gauze or cotton.
Second step takes tea oil, put be heated on charcoal fire or electric furnace 55 degrees centigrades (actual temp regard patient skin,
Need to there are boiling hot feeling but not injury skin).
Pack heat release oil the inside is warmed 10s or more by third step.Then there is skin at purpura with the pack point touching of heat, such as
This puts repeatedly applies repeatedly, 3 times a day, needs to change new drug every time, more than continuous January.
Feature and performance of the invention are described in further detail with reference to embodiments.
Embodiment 1
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 100 parts of ovate neolepisorus herb, 75 parts of tea oil.
The preparation method of aforementioned pharmaceutical compositions: ovate neolepisorus herb and tea oil are mixed.
Embodiment 2
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 180 parts of ovate neolepisorus herb, 120 parts of tea oil.
The preparation method of aforementioned pharmaceutical compositions: it after tea oil is first heated to 55 DEG C, then mixes with smashed ovate neolepisorus herb.
Embodiment 3
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 120 parts of ovate neolepisorus herb, 80 parts of tea oil.
The preparation method of aforementioned pharmaceutical compositions: it after tea oil is first heated to 60 DEG C, then mixes with smashed ovate neolepisorus herb.
Embodiment 4
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 160 parts of ovate neolepisorus herb, 100 parts of tea oil.
The preparation method of aforementioned pharmaceutical compositions: it after tea oil is first heated to 70 DEG C, then mixes with smashed ovate neolepisorus herb.
Embodiment 5
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 150 parts of ovate neolepisorus herb, 100 parts of tea oil.
The preparation method of aforementioned pharmaceutical compositions: it after tea oil is first heated to 55 DEG C, then mixes with smashed ovate neolepisorus herb.
Embodiment 6
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 120 parts of ovate neolepisorus herb, 100 parts of tea oil.
The preparation method of aforementioned pharmaceutical compositions: it after tea oil is first heated to 60 DEG C, then mixes with smashed ovate neolepisorus herb.
Embodiment 7
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 110 parts of ovate neolepisorus herb, 90 parts of tea oil.
The preparation method of aforementioned pharmaceutical compositions: it after tea oil is first heated to 65 DEG C, then mixes with smashed ovate neolepisorus herb.
Embodiment 8
It is a kind of to be mainly made of raw material for treating the pharmaceutical composition of anaphylactoid purpura, according to parts by weight, raw material packet
Include 165 parts of ovate neolepisorus herb, 80 parts of tea oil.
The preparation method of aforementioned pharmaceutical compositions: it after tea oil is first heated to 50 DEG C, then mixes with smashed ovate neolepisorus herb.
Typical case 1:
Chen, Guizhou Song Taoxian people, male, 10 months 2 years old when illness.In April, 2018, patient throw from bicycle and lead
Cause scrotum etc. redness, abdominal pain.It is checked to township hospital and buys medicine treatment, and converted wine with rural area herbal medicine and apply red and swollen position, two
Its rear foot bottom, shank, foot bow out existing blood cake.After enter the county hospital Song Tao, hospital considers that tumble injury row is infused anti-inflammatory, one week
The red and swollen discharge that disappears afterwards.Discharge same day evening disease relapse, abdominal pain aggravate, foot enlargement, on foot blood cake in flakes, some hairs of blood cake
It is bright.Enter the inspection of Tongren City the People's Hospital later and is diagnosed as anaphylactoid purpura, and hospitalization, row Amoxicillin, mountain LiangEqual medicines
Object one week treatment, the swelling simultaneously of purpura lighter mitigates, but abdominal pain is serious always, and it is invalid to be relieved pain with hormone, and discharge turns Chongqing
Army hospital, one week treatment.Abdominal pain disappears, and purpura also disappears substantially, leaves hospital.After discharge only two days again there is purpura, gradually plus
Weight, the pharmaceutical composition provided using the present embodiment 5, continuous treatment one month, purpura completely disappears, and no longer recurs in 1 year.
To sum up, pharmaceutical composition provided by the invention, the effect for treating anaphylactoid purpura is good, is not in the feelings of recurrence
Condition, and it is at low cost, preparation method is simple, is very beneficial to industrialization large-scale production.
Embodiments described above is a part of the embodiment of the present invention, instead of all the embodiments.Reality of the invention
The detailed description for applying example is not intended to limit the range of claimed invention, but is merely representative of selected implementation of the invention
Example.Based on the embodiments of the present invention, obtained by those of ordinary skill in the art without making creative efforts
Every other embodiment, shall fall within the protection scope of the present invention.
Claims (9)
1. a kind of for treating the pharmaceutical composition of anaphylactoid purpura, which is characterized in that be mainly made of raw material, in parts by weight
Meter, the raw material includes 100~180 parts of ovate neolepisorus herb, 75~120 parts of tea oil.
2. according to claim 1 for treating the pharmaceutical composition of anaphylactoid purpura, which is characterized in that the raw material packet
Include 120~160 parts of the ovate neolepisorus herb, 80~100 parts of the tea oil.
3. according to claim 2 for treating the pharmaceutical composition of anaphylactoid purpura, which is characterized in that the raw material packet
Include 150 parts of the ovate neolepisorus herb, 100 parts of the tea oil.
4. according to claim 1-3 for treating the pharmaceutical composition of anaphylactoid purpura, which is characterized in that institute
It states ovate neolepisorus herb and selects herb or leaf.
5. a kind of such as according to claim 1-3 for treating the preparation side of the pharmaceutical composition of anaphylactoid purpura
Method, which is characterized in that mix the ovate neolepisorus herb and the tea oil.
6. according to claim 5 for treating the preparation method of the pharmaceutical composition of anaphylactoid purpura, which is characterized in that
It will first be mixed again with the ovate neolepisorus herb after tea oil heating.
7. according to claim 6 for treating the preparation method of the pharmaceutical composition of anaphylactoid purpura, which is characterized in that
The tea oil is heated to 50 DEG C~70 DEG C.
8. according to claim 5 for treating the preparation method of the pharmaceutical composition of anaphylactoid purpura, which is characterized in that
Before the ovate neolepisorus herb and the tea oil are mixed, the ovate neolepisorus herb is crushed.
9. according to claim 8 for treating the preparation method of the pharmaceutical composition of anaphylactoid purpura, which is characterized in that
The ovate neolepisorus herb is crushed to 60~100 mesh.
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| CN201910331182.3A CN109876058A (en) | 2019-04-23 | 2019-04-23 | A kind of pharmaceutical composition and preparation method thereof for treating anaphylactoid purpura |
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| CN201910331182.3A CN109876058A (en) | 2019-04-23 | 2019-04-23 | A kind of pharmaceutical composition and preparation method thereof for treating anaphylactoid purpura |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115448927A (en) * | 2022-10-20 | 2022-12-09 | 重庆瑞泊莱医药科技有限公司 | Epinastine hydrobromide crystal form II and preparation method thereof |
-
2019
- 2019-04-23 CN CN201910331182.3A patent/CN109876058A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 江苏新医学院编: "《中药大辞典》", 31 May 1986, 上海科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115448927A (en) * | 2022-10-20 | 2022-12-09 | 重庆瑞泊莱医药科技有限公司 | Epinastine hydrobromide crystal form II and preparation method thereof |
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Address after: 554300 Kaihang Road 238, Chuandong Education Park, Bijiang District, Tongren City, Guizhou Province Applicant after: tongren university Address before: 554300 Kaihang Road 238, Chuandong Education Park, Bijiang District, Tongren City, Zunyi City, Guizhou Province Applicant before: tongren university |
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Application publication date: 20190614 |
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