CN109867001A - Liver tumour marker enzyme detection reagent device in a kind of serum - Google Patents
Liver tumour marker enzyme detection reagent device in a kind of serum Download PDFInfo
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- CN109867001A CN109867001A CN201910283565.8A CN201910283565A CN109867001A CN 109867001 A CN109867001 A CN 109867001A CN 201910283565 A CN201910283565 A CN 201910283565A CN 109867001 A CN109867001 A CN 109867001A
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Abstract
The invention discloses liver tumour marker enzyme detection reagent devices in a kind of serum, including incubator and two movable plates, symmetrical side plate there are two being fixedly connected at the top of the incubator, side on the movable plate close to bottom offers through-hole and slidably connects locating rod by through-hole, the opposite end of two locating rods is fixedly connected with the two sides of incubator, surface in the locating rod close to incubator one end is cased with pressure spring, and the both ends of the pressure spring are fixedly connected with the opposite side of movable plate and incubator.The present invention, pass through being used cooperatively between above structure, it solves in actual use since traditional kit is difficult to realize detection reagent heat preservation operation when in use, easily reduce reagent inactivation or activity, there are partly precipitateds after long-time stands storage for the reagent that kit takes out simultaneously, it also needs to be shaken up when in use, increases the amount of labour of doctor.To using the problem of making troubles.
Description
Technical field
The present invention relates to reagent storage technical field, liver tumour marker enzyme detection reagent device in specially a kind of serum.
Background technique
Tumour is the cell clone of a fast breeding, and the biochemical reaction process of tumour cell is related to a large amount of enzyme, albumen, swashs
Element etc., there is only the variations of expression quantity, and there are the expression of the variation of isozymogram and ectopic hormone, these variations are often
Indicate the occurrence and development of tumour.The variation for detecting these indexs has biggish clinical value, is that clinician is frequent
Reference index；Tumor markers are also known as tumor marker, refer to that characteristic is present in malignant cell, or by pernicious swollen
The substance that substance that oncocyte generates extremely or host generate the stimulate the reaction of tumour, and can reflect tumour occur, hair
Exhibition, a substance of the monitoring tumour to therapeutic response.Tumor markers are present in the tissue, body fluid and excreta of tumor patient
In, it can be detected with the method for immunology, biology and chemistry；In clinical application, we will select different according to sign
Enzyme is checked, to make correct diagnosis；Thus it has been proposed that a kind of blood that can be commonly used convenient for Various Hospitalss
Liver tumour marks enzyme detection kit in clear, liver tumour label in a kind of serum as disclosed in Chinese patent CN202101995U
Enzyme detection kit includes rectangular box and the box cover with one side edge bending disjunctor, and reagent rack is placed in box body,
There are 4 circular socket holes in reagent rack, is formed with receiving gamma glutamyl transpeptidase reagent bottle, alpha-L-fucosidase reagent respectively
Bottle, lactic dehydrogenase reagent bottle, alkaline phosphatase reagent bottle.The utility model patent is carried out according to using enzyme coupling rate method
Gamma glutamyl transpeptidase, alpha-L-fucosidase, lactic dehydrogenase, alkaline phosphatase test and analyze, and are suitable for liver tumour patient
Diagnosis can be used for automatically measuring, be suitable for medical treatment at different levels and scientific research institutions use convenient for universal；But traditional reagent
Box, which is difficult to realize detection reagent when in use, keeps the temperature operation, easily reduces reagent inactivation or activity, while kit taking-up
Reagent, there are partly precipitated, also needs to be shaken up when in use, increases the amount of labour of doctor after long-time stands storage.
It makes troubles to using.
Summary of the invention
The purpose of the present invention is to provide liver tumour marker enzyme detection reagent devices in a kind of serum, carry out to conventional apparatus
It improves, solves the problems in background technique.
To achieve the above object, the invention provides the following technical scheme: liver tumour marker enzyme detection reagent in a kind of serum
Device, including incubator and two movable plates, are fixedly connected with that there are two symmetrical side plate, the movements at the top of the incubator
Side on plate close to bottom offers through-hole and slidably connects locating rod, the opposite end of two locating rods by through-hole
It being fixedly connected with the two sides of incubator, the surface in the locating rod close to incubator one end is cased with pressure spring, and the two of the pressure spring
End is fixedly connected with the opposite side of movable plate and incubator.
Through slot one is offered on front side of the movable plate, the inner wall of the through slot one slidably connects traveller one, the cunning
The rear end of column one is fixedly connected with cursor, opens up fluted on front side of the side plate, and the surface of the cursor passes through pin shaft
It is rotatablely connected with the inner wall of groove, the surface of the cursor offers through slot two, and the inner wall of the through slot two slidably connects
Traveller two, the rear end of the traveller two are fixedly connected with connecting rod, and the bottom of the connecting rod is fixedly connected with thermal insulation board, described
The side of thermal insulation board and the inner wall of incubator are slidably connected, and the upper surface of the thermal insulation board offers through-hole and slided by through-hole
It is connected with test tube.
Framework is fixedly connected at the top of the side plate, the inner wall of the framework is fixedly connected with pillar, the pillar
Top is fixedly connected with sphere, and the surface rotation-limited of the sphere has turntable, and the upper surface of the turntable is equipped with rubber strip, institute
The inner wall on the surface and rubber strip of stating test tube is slidably connected, and the upper surface of the framework is fixedly connected with motor, on the motor
The bottom of output shaft runs through the upper surface of framework and is fixedly connected with pivoted arm, by proximal edge on the bottom of the pivoted arm and turntable
Upper surface slide connection.
Preferably, the bottom of the incubator is fixedly connected with pedestal, the pedestal position truncated cone-shaped pedestal, and pedestal is suitable for reading
The relatively large one end of diameter is downward.
Preferably, the phase back side of described two movable plates is fixedly connected to non-slip mat, the side of the non-slip mat
Offer finger slot.
Preferably, one end in the locating rod far from incubator is fixedly connected with baffle, and the side of the baffle can be with
The side of movable plate is flexibly connected.
Preferably, the quantity of through-hole is no less than five on the thermal insulation board, and above-mentioned through-hole is uniform on thermal insulation board
Distribution.
Preferably, the upper surface of the turntable offers sliding slot, and the basal sliding of the inner wall and pivoted arm of the sliding slot connects.
Preferably, the bottom of the pivoted arm is arcwall face, and the inner wall of the arcwall face and sliding slot on pivoted arm is slidably connected.
Compared with prior art, beneficial effects of the present invention are as follows:
One, the present invention is that detection reagent persistently keeps constant temperature by incubator, and test agent is made to be able to maintain high activity state；It moves
Movable plate plays transmission effect；By the limitation of locating rod, guarantee stability when movable plate moves left and right；When pressing, overcoming
After the elastic force of pressure spring, moving toward one another for two movable plates is realized；After releasing to the opposite pressing of movable plate, in the elastic force of pressure spring
Under effect, so that two movable plates carry out being away from each other movement；Through slot one plays the role of limit and guidance；Traveller one plays transmission
Effect；In use, traveller one moves down in through slot one, and then makes cursor when two movable plates are moved toward one another
It is rotated in groove, one end on cursor far from movable plate tilts, and the upper of thermal insulation board is realized in the transmission through connecting rod
It moves, and then test tube is driven to rising together, and then facilitate and take test tube from thermal insulation board away；It together should two movable plates progress phases
When away from movement, thermal insulation board can decline and engage with the inner wall of incubator, realize sealing thermal insulation；
Two, the present invention plays fixed function by framework, and the lower surface of turntable offers arch groove compatible with sphere and leads to
The engaging that arch groove completes the two is crossed, turntable can be freely rotated on sphere；Test tube is fixed on the upper of turntable by rubber strip
Surface is simultaneously freely rotated with turntable, and then realizes that reagent shakes up in test tube；The rotation of pivoted arm, pivoted arm are driven by motor
Bottom slided on the upper surface of turntable so that turntable is rotated using the sphere on pillar as center of rotation；
Three, the present invention solves in actual use by being used cooperatively between above structure due to traditional reagent
Box, which is difficult to realize detection reagent when in use, keeps the temperature operation, easily reduces reagent inactivation or activity, while kit taking-up
Reagent, there are partly precipitated, also needs to be shaken up when in use, increases the amount of labour of doctor after long-time stands storage.
To using the problem of making troubles.
Detailed description of the invention
Fig. 1 is the elevational cross-sectional view of structure of the invention；
Fig. 2 is the top view of sliding slot of the present invention.
In figure: 1- incubator, 2- side plate, 3- movable plate, 4- locating rod, 5- pressure spring, 6- through slot one, 7- traveller one, 8- turn
Swing arm, 9- groove, 10- through slot two, 11- traveller two, 12- connecting rod, 13- thermal insulation board, 14- test tube, 15- framework, 16- pillar,
17- turntable, 18- rubber strip, 19- motor, 20- pivoted arm, 21- pedestal, 22- non-slip mat, 23- baffle, 24- sliding slot.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Fig. 1 to Fig. 2 is please referred to, the present invention provides a kind of technical solution: liver tumour marker enzyme detection reagent in a kind of serum
Device, including incubator 1 and two movable plates 3, incubator 1 have the effect of persistently keeping constant temperature for detection reagent, make to test
Reagent is able to maintain high activity state, mainly realizes intermittent heat supply after being powered up by heating wire in incubator 1, simultaneously
Also masking foil is posted in incubator, for reinforcing heat insulation effect, movable plate 3 plays transmission effect, and the bottom of incubator 1 is fixed to be connected
Pedestal 21,21 truncated cone-shaped pedestals of pedestal are connected to, and the relatively large one end of bore downward, passes through setting for pedestal 21 on pedestal 21
It sets, improves stability when device integrally uses, be not susceptible to shake；And the setting of truncated cone-shaped pedestal, and bore on pedestal 21
Relatively large one end downward, increases the contact area with supporting surface, further increases the stability of device entirety, two movements
The phase back side of plate 3 is fixedly connected to non-slip mat 22, and the side of non-slip mat 22 offers finger slot, by the setting of non-slip mat 22,
It when carrying out opposite squeeze to two movable plates 3, is not easy to skid, and refers to the setting of slot thereon, prevent when further increasing pressing
Sliding effect, the top of incubator 1 are fixedly connected there are two symmetrical side plate 2, are offered on movable plate 3 close to the side of bottom logical
Hole simultaneously slidably connects locating rod 4 by through-hole, by the limitation of locating rod 4, guarantees stabilization when movable plate 3 moves left and right
Property, one end in locating rod 4 far from incubator 1 is fixedly connected with baffle 23, and the side of baffle 23 can be living with the side of movable plate 3
Dynamic connection is avoided after releasing to the pressing of pressure spring 5 by the setting of baffle 23, and the elastic force of pressure spring 5 discharges suddenly, so that moving
The mobile excess of movable plate 3 is fixed departing from the contact of locating rod 4, the opposite end of two locating rods 4 and the two sides of incubator 1
Connection, the surface in locating rod 4 close to 1 one end of incubator are cased with pressure spring 5, when pressing, after the elastic force for overcoming pressure spring 5, realize
Two movable plates 3 move toward one another；After releasing to the opposite pressing of movable plate 3, under the elastic force effect of pressure spring 5, so that two
A movable plate 3 carries out being away from each other movement；The both ends of pressure spring 5 are fixedly connected with the opposite side of movable plate 3 and incubator 1.
The front side of movable plate 3 offers through slot 1, and through slot 1 plays the role of limit and guidance, the inner wall of through slot 1
Traveller 1 is slidably connected, traveller 1 plays transmission effect, and the rear end of traveller 1 is fixedly connected with cursor 8, side plate 2
Front side opens up fluted 9, and the surface of cursor 8 is rotatablely connected by the inner wall of pin shaft and groove 9, and the surface of cursor 8 opens up
There is through slot 2 10, the inner wall of through slot 2 10 slidably connects traveller 2 11, and the rear end of traveller 2 11 is fixedly connected with connecting rod 12,
The bottom of connecting rod 12 is fixedly connected with thermal insulation board 13, in use, traveller 1 exists when two movable plates 3 are moved toward one another
It is moved down in through slot 1, and then rotates cursor 8 in groove 9, one end on cursor 8 far from movable plate 3 is stuck up
It rises, the transmission through connecting rod 12, realizes moving up for thermal insulation board 13, and then test tube 14 is driven to rising together, and then facilitate and will try
Pipe is taken away from thermal insulation board 13, with should two movable plates 3 carry out being away from each other movement when, thermal insulation board 13 can decline and with heat preservation
The inner wall of case 1 engages, and realizes sealing thermal insulation；The quantity of through-hole is no less than five on thermal insulation board 13, and above-mentioned through-hole is in thermal insulation board
It is uniformly distributed on 13, test tube 14 is realized by the through-hole on thermal insulation board 13 and fixed, and it is many to be uniformly distributed quantity on thermal insulation board 13
In five through-holes, guarantees that sufficient amount of test tube can be placed in incubator 1 and store sufficient amount of reagent, thermal insulation board 13
Side and the inner wall of incubator 1 be slidably connected, the upper surface of thermal insulation board 13 offers through-hole and is slidably connected by through-hole
Test tube 14, test tube 14 are the test tube that end is sealed, and are always maintained at sealing state before not breaking a seal；
The top of side plate 2 is fixedly connected with framework 15, and framework 15 plays fixed function, and the inner wall of framework 15 is fixedly connected with pillar
16, the top of pillar 16 is fixedly connected with sphere, and the surface rotation-limited of sphere has turntable 17, and the lower surface of turntable 17 offers
Arch groove compatible with sphere and the engaging that the two is completed by arch groove, turntable 17 can be freely rotated on sphere, turntable
17 upper surface offers sliding slot 24, and the inner wall of sliding slot 24 is connect with the basal sliding of pivoted arm 20, by the setting of sliding slot 24, protects
The upper surface of the stability that rotates on turntable 17 of card pivoted arm 20, turntable 17 is equipped with rubber strip 18, by rubber strip by test tube 14
It is fixed on the upper surface of turntable 17 and is freely rotated with turntable 17, and then realize that reagent shakes up in test tube 14；Test tube 14
Surface and the inner wall of rubber strip 18 be slidably connected, the upper surface of framework 15 is fixedly connected with motor 19, output shaft on motor 19
Bottom through framework 15 upper surface and be fixedly connected with pivoted arm 20, pass through motor 19 drive pivoted arm 20 rotation, pivoted arm 20
Bottom slided on the upper surface of turntable 17 so that turntable 17 is rotated using the sphere on pillar 16 as center of rotation, turn
The bottom of arm 20 is arcwall face, and the inner wall of the arcwall face on pivoted arm 20 and sliding slot 24 is slidably connected, and passes through 20 bottom arc of pivoted arm
The setting in shape face leans on proximal edge so that sliding of the pivoted arm 20 in sliding slot 24 is more smooth on the bottom of pivoted arm 20 and turntable 17
Upper surface slide connection.
Working principle: liver tumour marker enzyme detection reagent device when in use, when pressing, is overcoming pressure spring 5 in the serum
Elastic force after, realize moving toward one another for two movable plates 3；After releasing to the opposite pressing of movable plate 3, in the elastic force of pressure spring 5
Under effect, so that two movable plates 3 carry out being away from each other movement；When two movable plates 3 are moved toward one another, traveller 1 is logical
It is moved down in slot 1, and then rotates cursor 8 in groove 9, one end on cursor 8 far from movable plate 3 is stuck up
It rises, the transmission through connecting rod 12, realizes moving up for thermal insulation board 13, and then test tube 14 is driven to rising together, and then facilitate and will try
Pipe is taken away from thermal insulation board 13；With should two movable plates 3 carry out being away from each other movement when, thermal insulation board 13 can decline and with heat preservation
The inner wall of case 1 engages, and realizes sealing thermal insulation；The lower surface of turntable 17 offers arch groove compatible with sphere and passes through cambered surface
Slot completes the engaging of the two, and turntable 17 can be freely rotated on sphere；Test tube 14 is fixed on turntable 17 by rubber strip 18
Upper surface is simultaneously freely rotated with turntable 17, and then realizes that reagent shakes up in test tube 14；Pivoted arm 20 is driven by motor 19
Rotation, the bottom of pivoted arm 20 slides on the upper surface of turntable 17, so that turntable 17 is in rotation with the sphere on pillar 16
The heart is rotated；By being used cooperatively between above structure, solve in actual use due to traditional kit
It is difficult to realize detection reagent heat preservation operation when in use, easily reduces reagent inactivation or activity, while the examination that kit takes out
Agent, there are partly precipitated, also needs to be shaken up when in use, increases the amount of labour of doctor after long-time stands storage.It gives
The problem of using making troubles.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (7)
1. liver tumour marker enzyme detection reagent device in a kind of serum, it is characterised in that: including incubator (1) and two movable plates
(3), there are two being fixedly connected at the top of the incubator (1) symmetrical side plate (2), close to bottom on the movable plate (3)
Side offers through-hole and is slidably connected locating rod (4) by through-hole, the opposite end of two locating rods (4) and incubator
(1) two sides are fixedly connected, and the surface on the locating rod (4) close to incubator (1) one end is cased with pressure spring (5), the pressure spring
(5) both ends are fixedly connected with the opposite side of movable plate (3) and incubator (1)；
Through slot one (6) is offered on front side of the movable plate (3), the inner wall of the through slot one (6) slidably connects traveller one
(7), the rear end of the traveller one (7) is fixedly connected with cursor (8), opens up fluted (9), institute on front side of the side plate (2)
The surface for stating cursor (8) is rotatablely connected by pin shaft and the inner wall of groove (9), and the surface of the cursor (8) offers logical
Slot two (10), the inner wall of the through slot two (10) slidably connect traveller two (11), and the rear end of the traveller two (11) is fixed to be connected
It is connected to connecting rod (12), the bottom of the connecting rod (12) is fixedly connected with thermal insulation board (13), the side of the thermal insulation board (13)
It is slidably connected with the inner wall of incubator (1), the upper surface of the thermal insulation board (13) offers through-hole and is slidably connected by through-hole
There are test tube (14)；
It being fixedly connected with framework (15) at the top of the side plate (2), the inner wall of the framework (15) is fixedly connected with pillar (16),
Sphere is fixedly connected at the top of the pillar (16), the surface rotation-limited of the sphere has turntable (17), the turntable
(17) upper surface is equipped with rubber strip (18), and the surface of the test tube (14) and the inner wall of rubber strip (18) are slidably connected, described
The upper surface of framework (15) is fixedly connected with motor (19), and the bottom of output shaft is through the upper of framework (15) on the motor (19)
Surface is simultaneously fixedly connected with pivoted arm (20), and the upper surface slide on the bottom and turntable (17) of the pivoted arm (20) by proximal edge connects
It connects.
2. liver tumour marker enzyme detection reagent device in a kind of serum according to claim 1, it is characterised in that: the guarantor
The bottom of incubator (1) is fixedly connected with pedestal (21), pedestal (21) position truncated cone-shaped pedestal, and bore is opposite on pedestal (21)
Biggish one end is downward.
3. liver tumour marker enzyme detection reagent device in a kind of serum according to claim 1, it is characterised in that: two institutes
The phase back side for stating movable plate (3) is fixedly connected to non-slip mat (22), and the side of the non-slip mat (22) offers finger slot.
4. liver tumour marker enzyme detection reagent device in a kind of serum according to claim 1, it is characterised in that: described fixed
One end on position bar (4) far from incubator (1) is fixedly connected with baffle (23), and the side of the baffle (23) can be with movable plate
(3) side is flexibly connected.
5. liver tumour marker enzyme detection reagent device in a kind of serum according to claim 1, it is characterised in that: it is described every
The quantity of through-hole is no less than five on hot plate (13), and above-mentioned through-hole is uniformly distributed on thermal insulation board (13).
6. liver tumour marker enzyme detection reagent device in a kind of serum according to claim 1, it is characterised in that: described turn
The upper surface of disk (17) offers sliding slot (24), and the inner wall of the sliding slot (24) is connect with the basal sliding of pivoted arm (20).
7. liver tumour marker enzyme detection reagent device in a kind of serum according to claim 1, it is characterised in that: described turn
The bottom of arm (20) is arcwall face, and the inner wall of the arcwall face on pivoted arm (20) and sliding slot (24) is slidably connected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910283565.8A CN109867001B (en) | 2019-04-10 | 2019-04-10 | Reagent device for detecting liver tumor marker enzyme in serum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910283565.8A CN109867001B (en) | 2019-04-10 | 2019-04-10 | Reagent device for detecting liver tumor marker enzyme in serum |
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| Publication Number | Publication Date |
|---|---|
| CN109867001A true CN109867001A (en) | 2019-06-11 |
| CN109867001B CN109867001B (en) | 2020-10-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910283565.8A Active CN109867001B (en) | 2019-04-10 | 2019-04-10 | Reagent device for detecting liver tumor marker enzyme in serum |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206868130U (en) * | 2017-05-26 | 2018-01-12 | 仕承生物工程（上海）有限公司 | A kind of three-dimensional mixer |
| CN207254223U (en) * | 2017-09-22 | 2018-04-20 | 河北奇正环境科技有限公司 | Turning motion device is used in a kind of reagent detection |
| CN207562957U (en) * | 2017-12-07 | 2018-07-03 | 刘平 | A kind of external diagnosis reagent rack |
| CN108516198A (en) * | 2018-05-29 | 2018-09-11 | 中国地质大学（武汉） | A kind of large size water conservancy and hydropower geotechnical investigation soil sample storage box |
-
2019
- 2019-04-10 CN CN201910283565.8A patent/CN109867001B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206868130U (en) * | 2017-05-26 | 2018-01-12 | 仕承生物工程（上海）有限公司 | A kind of three-dimensional mixer |
| CN207254223U (en) * | 2017-09-22 | 2018-04-20 | 河北奇正环境科技有限公司 | Turning motion device is used in a kind of reagent detection |
| CN207562957U (en) * | 2017-12-07 | 2018-07-03 | 刘平 | A kind of external diagnosis reagent rack |
| CN108516198A (en) * | 2018-05-29 | 2018-09-11 | 中国地质大学（武汉） | A kind of large size water conservancy and hydropower geotechnical investigation soil sample storage box |
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| CN109867001B (en) | 2020-10-16 |
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