CN109865131B - Spirulina preparation for conditioning cardiovascular and cerebrovascular functions and preparation method and application thereof - Google Patents
Spirulina preparation for conditioning cardiovascular and cerebrovascular functions and preparation method and application thereof Download PDFInfo
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- CN109865131B CN109865131B CN201910256009.1A CN201910256009A CN109865131B CN 109865131 B CN109865131 B CN 109865131B CN 201910256009 A CN201910256009 A CN 201910256009A CN 109865131 B CN109865131 B CN 109865131B
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Abstract
The invention relates to the field of medical biology, and discloses a spirulina preparation for conditioning cardiovascular and cerebrovascular functions, and a preparation method and application thereof. The spirulina preparation for conditioning cardiovascular and cerebrovascular functions comprises the following components in parts by weight: 30-80 parts of spirulina, 10-30 parts of lophatherum gracile, 5-30 parts of honeysuckle, 5-30 parts of prickly pear, 1-5 parts of papain and 1-5 parts of cellulase. The invention also provides a preparation method of the preparation, which is simple and convenient to operate, convenient for parameter control and easy for realizing industrial production. The preparation of the invention can comprehensively condition the functions of heart and cerebral vessels, improve the functions of heart and cerebral vessels, protect heart and cerebral vessels and reduce the possibility of the occurrence of cardiovascular and cerebrovascular diseases to the maximum extent.
Description
Technical Field
The invention relates to the field of medical biology, in particular to a spirulina preparation for conditioning cardiovascular and cerebrovascular functions and a preparation method and application thereof.
Background
Cardiovascular and cerebrovascular diseases are the general names of cardiovascular and cerebrovascular diseases, and generally refer to ischemic or hemorrhagic diseases of heart, brain and systemic tissues caused by hyperlipidemia, blood viscosity, atherosclerosis, hypertension and the like. Cardiovascular and cerebrovascular diseases are common diseases seriously threatening the health of human beings, especially the health of middle-aged and elderly people over 50 years old. Has the characteristics of high morbidity, high disability rate and high mortality. Cardiovascular and cerebrovascular diseases are manifestations of systemic or systemic vasculopathy in the heart and brain. The etiology is mainly divided into 4 aspects: vascular factors such as atherosclerosis, hypertensive arteriosclerotic disease and arteritis; blood flow dynamics factors such as hypertension; dyshemorheology such as hyperlipidemia and diabetes; blood component factors such as leukemia, anemia and thrombocytosis.
Once a disease occurs, about more than 50% of survivors with cerebrovascular accidents still cannot take care of themselves completely even with the most advanced and sophisticated treatment methods. The number of people dying from cardiovascular and cerebrovascular diseases every year in the world is as high as 1500 thousands of people, and the people live at the first position of various causes of death. Therefore, more and more people pay attention to daily conditioning of the cardiovascular and cerebrovascular diseases, and the risk of the occurrence of the cardiovascular and cerebrovascular diseases is reduced to the maximum extent.
Disclosure of Invention
The invention provides a spirulina preparation for conditioning cardiovascular and cerebrovascular functions, a preparation method and application thereof, which can comprehensively regulate the cardiovascular and cerebrovascular functions, improve the cardiovascular and cerebrovascular functions and reduce the occurrence of cardiovascular and cerebrovascular diseases.
The technical scheme of the invention is realized as follows:
a spirulina preparation for conditioning cardiovascular and cerebrovascular functions comprises the following components in parts by weight: 30-80 parts of spirulina, 10-30 parts of lophatherum gracile, 5-30 parts of honeysuckle, 5-30 parts of prickly pear, 1-5 parts of papain and 1-5 parts of cellulase.
Further, the spirulina preparation for conditioning cardiovascular and cerebrovascular functions comprises the following components in parts by weight: 50 parts of spirulina, 20 parts of lophatherum gracile, 20 parts of honeysuckle, 15 parts of cactus fruit, 3 parts of papain and 3 parts of cellulase.
The preparation method of the spirulina compound preparation for conditioning the cardiovascular and cerebrovascular functions comprises the following steps:
(1) taking lophatherum gracile and honeysuckle according to the formula amount, adding water for decoction, filtering to remove filter residue, and drying the filtrate to obtain an extract; mixing cactus fruit with cellulase, squeezing, and removing fruit residue to obtain fruit juice;
(2) and (2) mixing the spirulina and the papain with the extract and the fruit juice obtained in the step (1) according to the formula ratio, and drying to obtain the preparation.
Further, in the step (1), in the process of decocting the lophatherum gracile and the honeysuckle, water which is 5-8 times of the total amount of the medicinal materials is added, and the decoction is carried out for 3 times, and each time lasts for 15-20 minutes.
Further, water is continuously added in the squeezing process of the cactus fruits in the step (1) until all the juice is squeezed out.
Further, in the step (2), a freeze drying method is adopted for drying.
The spirulina replication agent for conditioning the cardiovascular and cerebrovascular functions is applied to preparation of a preparation for conditioning the cardiovascular and cerebrovascular functions.
A medicine for regulating cardiovascular and cerebrovascular functions comprises the above Spirulina preparation and adjuvants.
Furthermore, the dosage form of the medicine is an oral preparation.
Furthermore, the dosage form of the medicine is tablets, granules, powder, pills and capsules.
The invention has the beneficial effects that:
the spirulina can reduce cholesterol, regulate blood sugar, protect intestines and stomach, resist oxidation, aging and fatigue and comprehensively improve immunity. Lophatherum gracile has the effects of cooling and relieving heat, clearing away heart-fire and removing dysphoria, and honeysuckle flower has the effects of clearing away heat and toxic materials. Papain is a plant protease, and has antiinflammatory, cholagogic, and digestion promoting effects. The prickly pear contains rich trace elements, protein and other beneficial components, and can promote the expansion and regeneration of normal limit cells of human body, and the cellulase can decompose cellulose in prickly pear and extract the active components from prickly pear to the maximum extent. The components are compatible for use, so that the cholesterol and the blood fat can be effectively reduced, the blood sugar level can be adjusted, the garbage in blood vessels can be removed, the damaged blood vessels can be repaired, and the cardiovascular and cerebrovascular functions can be recovered. The preparation of the invention can comprehensively condition cardiovascular and cerebrovascular functions, improve cardiovascular and cerebrovascular functions, protect the cardiovascular and cerebrovascular, reduce the possibility of cardiovascular and cerebrovascular diseases to the maximum extent, and has obvious curative effect on conditioning the cardiovascular and cerebrovascular.
The invention also provides a preparation method of the preparation, which is simple and convenient to operate, convenient for parameter control and easy for realizing industrial production.
Detailed Description
The technical solutions in the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A spirulina preparation for conditioning cardiovascular and cerebrovascular functions comprises the following components in parts by weight: 30 parts of spirulina, 10 parts of lophatherum gracile, 5 parts of honeysuckle, 5 parts of prickly pear, 1 part of papain and 1 part of cellulase.
The preparation method of the spirulina preparation for conditioning the cardiovascular and cerebrovascular functions comprises the following steps:
(1) taking lophatherum gracile and honeysuckle according to the formula amount, adding water which is 5-8 times of the total amount of the medicinal materials, decocting for 3 times, 15-20 minutes each time, filtering to remove filter residues, and drying the filtrate to obtain an extract; mixing cactus fruit with cellulase, squeezing, and removing fruit residue to obtain fruit juice; continuously adding water in the squeezing process until all the juice is squeezed out;
(2) and (2) mixing the spirulina and the papain with the extract and the fruit juice obtained in the step (1) according to the formula ratio, and then freezing and drying to obtain the preparation.
Example 2
A spirulina preparation for conditioning cardiovascular and cerebrovascular functions comprises the following components in parts by weight: 50 parts of spirulina, 20 parts of lophatherum gracile, 20 parts of honeysuckle, 15 parts of cactus fruit, 3 parts of papain and 3 parts of cellulase.
The preparation method of the spirulina preparation for conditioning the cardiovascular and cerebrovascular functions comprises the following steps:
(1) taking lophatherum gracile and honeysuckle according to the formula amount, adding water which is 5-8 times of the total amount of the medicinal materials, decocting for 3 times, 15-20 minutes each time, filtering to remove filter residues, and drying the filtrate to obtain an extract; mixing cactus fruit with cellulase, squeezing, and removing fruit residue to obtain fruit juice; continuously adding water in the squeezing process until all the juice is squeezed out;
(2) and (2) mixing the spirulina and the papain with the extract and the fruit juice obtained in the step (1) according to the formula ratio, and then freezing and drying to obtain the preparation.
Example 3
A spirulina preparation for conditioning cardiovascular and cerebrovascular functions comprises the following components in parts by weight: 80 parts of spirulina, 30 parts of lophatherum gracile, 30 parts of honeysuckle, 30 parts of prickly pear, 5 parts of papain and 5 parts of cellulase.
The preparation method of the spirulina preparation for conditioning the cardiovascular and cerebrovascular functions comprises the following steps:
(1) taking lophatherum gracile and honeysuckle according to the formula amount, adding water which is 5-8 times of the total amount of the medicinal materials, decocting for 3 times, 15-20 minutes each time, filtering to remove filter residues, and drying the filtrate to obtain an extract; mixing cactus fruit with cellulase, squeezing, and removing fruit residue to obtain fruit juice; continuously adding water in the squeezing process until all the juice is squeezed out;
(2) and (2) mixing the spirulina and the papain with the extract and the fruit juice obtained in the step (1) according to the formula ratio, and then freezing and drying to obtain the preparation.
Example 4
A medicine for regulating cardiovascular and cerebrovascular functions comprises the above Spirulina preparation and adjuvants. The dosage form of the medicine can be selected from oral preparations such as tablets, granules, powder, pills, capsules and the like. The auxiliary materials can be pharmaceutically acceptable according to different formulations.
Study of the therapeutic Effect of the preparation of the present invention
124 patients with symptoms of hyperlipidemia, hypertension or hypertriglyceridemia are randomly selected and divided into 4 groups, the spirulina preparation or the prepared medicine is respectively administered to the patients with serious diseases three times a day, the patients with mild diseases twice a day, and the patients take the medicine for three treatment courses continuously every 15 days. The original living habits and diet are maintained during the taking period. The blood pressure, total cholesterol and triglyceride data before and after administration were measured, respectively, and the average values were obtained. After the experiment was completed, the condition of each group of patients was counted according to the following criteria. The results are shown in tables 1-2.
Criteria for evaluating therapeutic effects
(1) The effect is shown: clinical symptoms disappear, and the function returns to normal. No recurrence was observed after withdrawal.
(2) The improvement is as follows: the clinical symptoms are relieved, and the state of the disease is stable. The disease condition is repeated after stopping taking the medicine.
(3) And (4) invalidation: no improvement in clinical symptoms.
TABLE 1 comparison of examination indexes of patients before and after administration
As can be seen from Table 1, the administration of the formulations or medicaments of the 4 embodiments of the present invention can significantly reduce the symptoms of hypertension, hyperlipidemia or hypertriglyceridemia in patients. The spirulina preparation and the medicine prepared by the preparation have obvious regulation effect on cardiovascular and cerebrovascular diseases such as hypertension, hyperlipidemia or hypertriglyceridemia and the like.
TABLE 2 statistics of efficacy
As can be seen from Table 2, the spirulina preparation and the medicine prepared from the preparation in 4 embodiments of the invention have the curative effect of more than 90%.
In addition, the patient does not have any uncomfortable reaction in the whole experimental process, which indicates that the spirulina preparation and the medicine prepared by the preparation are safe to use and have no toxic or side effect.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (7)
1. An application of a spirulina preparation in preparing a preparation for regulating cardiovascular and cerebrovascular functions is characterized in that:
the spirulina preparation consists of the following components in parts by weight: 50 parts of spirulina, 20 parts of lophatherum gracile, 20 parts of honeysuckle, 15 parts of prickly pear, 3 parts of papain and 3 parts of cellulase;
the preparation method of the spirulina preparation comprises the following steps:
(1) taking lophatherum gracile and honeysuckle according to the formula amount, adding water for decoction, filtering to remove filter residue, and drying the filtrate to obtain an extract; mixing cactus fruit with cellulase, squeezing, and removing fruit residue to obtain fruit juice;
(2) and (2) mixing the spirulina and the papain in a formula amount with the extract and the fruit juice obtained in the step (1), and drying to obtain the spirulina preparation.
2. The use of claim 1, wherein: in the step (1), in the process of decocting the lophatherum gracile and the honeysuckle, water which is 5-8 times of the total amount of the medicinal materials is added, and the decoction is carried out for 3 times, 15-20 minutes each time.
3. The use of claim 1, wherein: and (2) continuously adding water in the squeezing process of the cactus fruits in the step (1) until all the fruit juice is squeezed out.
4. The use of claim 1, wherein: in the step (2), the freeze drying method is adopted for drying.
5. A medicine for conditioning cardiovascular and cerebrovascular functions is characterized in that: comprising the spirulina formulation of claim 1 and adjuvants.
6. The medicament of claim 5, wherein: the dosage form of the medicine is oral preparation.
7. The medicament of claim 5, wherein: the dosage forms of the medicine are tablets, granules, powder, pills and capsules.
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| CN101288697A (en) * | 2008-06-10 | 2008-10-22 | 华中农业大学 | Medicinal composition for reducing fat, blood pressure, blood sugar, cholesterin and blood fat |
| CN101301351A (en) * | 2008-06-20 | 2008-11-12 | 刘树平 | Capsules for treating cardiovascular and cerebrovascular diseases and method for preparing the same |
| CN101911991A (en) * | 2010-08-03 | 2010-12-15 | 马伟光 | Spirulina health-care tea and preparation method thereof |
| CN102178233A (en) * | 2011-04-22 | 2011-09-14 | 南宁大单生物科技有限责任公司 | Spirulina nutrient solution |
| CN105586241A (en) * | 2016-03-22 | 2016-05-18 | 李琪 | Making method of cactus pear fruit vinegar |
| CN107137644A (en) * | 2017-05-19 | 2017-09-08 | 广西巴马德爱三通中草药有限责任公司 | Cardiovascular and cerebrovascular health preserving tea and preparation method thereof |
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