CN109833562A - A kind of disposable self-destructing vibration head assembly and the rush infiltration instrument using the component - Google Patents
A kind of disposable self-destructing vibration head assembly and the rush infiltration instrument using the component Download PDFInfo
- Publication number
- CN109833562A CN109833562A CN201711204592.9A CN201711204592A CN109833562A CN 109833562 A CN109833562 A CN 109833562A CN 201711204592 A CN201711204592 A CN 201711204592A CN 109833562 A CN109833562 A CN 109833562A
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- Prior art keywords
- destructing
- head assembly
- platform
- disposable self
- pedestal
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 230000008595 infiltration Effects 0.000 title abstract description 6
- 238000001764 infiltration Methods 0.000 title abstract description 6
- 230000000149 penetrating effect Effects 0.000 claims abstract description 5
- 206010020649 Hyperkeratosis Diseases 0.000 claims abstract description 4
- 208000001126 Keratosis Diseases 0.000 claims abstract description 4
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 27
- 238000007789 sealing Methods 0.000 claims description 6
- 239000011148 porous material Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 8
- 238000010521 absorption reaction Methods 0.000 abstract description 6
- 230000036541 health Effects 0.000 abstract description 3
- 238000004064 recycling Methods 0.000 abstract description 3
- 210000003491 skin Anatomy 0.000 description 14
- 230000003796 beauty Effects 0.000 description 6
- 210000002615 epidermis Anatomy 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 3
- 229960004194 lidocaine Drugs 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 2
- 229910021421 monocrystalline silicon Inorganic materials 0.000 description 2
- FGRBYDKOBBBPOI-UHFFFAOYSA-N 10,10-dioxo-2-[4-(N-phenylanilino)phenyl]thioxanthen-9-one Chemical compound O=C1c2ccccc2S(=O)(=O)c2ccc(cc12)-c1ccc(cc1)N(c1ccccc1)c1ccccc1 FGRBYDKOBBBPOI-UHFFFAOYSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 230000010165 autogamy Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002159 nanocrystal Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Percussion Or Vibration Massage (AREA)
Abstract
The invention discloses the rush infiltration instrument of a kind of disposable self-destructing vibration head assembly and the application component, and including hollow pressure part, the hollow inside of the pressure part is equipped with an inner core, twist off part connection by least one between the inner core and the pressure part;The inner core includes active section and linkage section, and the upper surface of the active section is equipped with the micro device for only penetrating keratoderma, offers annular slot in the circumferential direction of the linkage section;It further include connector, the upper end of the connector is equipped with the buckle matched with the annular slot, and lower end is equipped with platform.A kind of disposable self-destructing vibration head assembly of the invention and the rush infiltration instrument using the component, reach self-destruction effect by the way that the rotation of pressure part and inner core is disconnected, the problem of avoiding recycling has ensured the health of human body of user while guaranteeing that human skin improves absorption efficiency.
Description
Technical field
The present invention relates to percutaneous delivery instrument technical field more particularly to a kind of disposable self-destructing vibration head assembly and
Instrument is seeped using the rush of the component.
Background technique
Currently, nanometer micropin and nanometer chip can be used in medical treatment or beauty industry.By taking beauty industry as an example, human skin
With epidermis and corium, human body is that beauty product need to enter corium by epidermis can just be absorbed by the body smearing beauty product,
But due to the barrier effect of epidermis, limit the absorption efficiency of beauty product.Nanometer micropin is to open skin by nanotechnology
A kind of micropin of skin pipeline, syringe needle have been covered with close, thin small to what be can't see above similar to one piece slight of chip square
Needle can allow beauty product to enter epidermis by this small cube by the skin, and people is almost without feeling.Nanometer chip be
Promoted to seep specific purpose tool according to the nanometer of human skin mechanical development, be carved by monocrystalline silicon by nanotechnology technique.Nanometer
The surface of chip is a series of microneedle arrays, they can open the outmost cuticula of skin, while will not injure skin corium,
Greatly improve penetrating power of the pumped (conveying) medium on skin epidermis.The bio-compatibility of monocrystalline silicon in turn ensures that nano-crystal was using
Safety in journey.
Therefore, the epidermis of human skin can be punctured by nanometer micropin or nanometer chip, to get through skin passage.Such as
This will not cause wound, and improve the absorption efficiency of skin because not acting on corium to human body.To realize above-mentioned mesh
, nanometer micropin or nanometer chip can be placed on the platform of a plastic assembly, using nanometer micropin or nanometer chip to human body
Skin is acted on.In view of safe and healthy, the problem of preventing cross-infection, such product all requires user disposably to make
With still, the phenomenon that being reused in the market behavior in the case where interests drive frequently occurs, and this reuse is easy to lead
Cause disease infection and Bacterial infection of the user in aesthetic procedure.
Summary of the invention
In view of above-mentioned defect existing in the prior art, the purpose of the present invention is to propose to a kind of disposable self-destructing vibration heads
The rush of component and the application component seeps instrument.
To achieve the goals above, present invention employs following technical solutions:
A kind of disposable self-destructing vibration head assembly, including hollow pressure part, the hollow inside of the pressure part is equipped with
One inner core twists off part connection by least one between the inner core and the pressure part;The inner core includes active section and company
Connect section, the upper surface of the active section is equipped with the micro device for only penetrating keratoderma, in the circumferential direction of the linkage section
Offer annular slot;It further include connector, the upper end of the connector is equipped with the buckle matched with the annular slot, under
End is equipped with platform.
Further, the inner surface of the pressure part is equipped with salient point.
Further, by twisting off part connection described in 4 between the inner core and the pressure part.
Further, the cross section of the active section of the pressure part and the inner core is circle.
Further, the cross section of the linkage section of the inner core be triangle or square, the connector it is upper
The buckle at end is the three-clove style buckle or fFour piece type buckle matched with the linkage section.
Further, the micro device is nanometer micropin or nanometer chip.
Further, the lower end of the connector is equipped with connection card slot, and the platform is buckled equipped with platform, the connection
Part is solidly connected with the platform by the connection card slot and the platform snap lock.
A kind of rush infiltration instrument, vibrates head assembly including above-mentioned disposable self-destructing, with the disposable self-destructing vibration head
The upper housing that component is detachably connected, and the lower case being detachably connected with the upper housing;The lower case is fixed on bottom
On seat, power supply module, and the motor being electrically connected with the power supply module, a shaft are equipped in the pedestal and the lower case
One end connect with the motor driven, the other end and the disposable self-destructing vibration head assembly the platform offset;Institute
It states and is equipped with locating part in upper housing, the connector is arranged in the locating part, and the platform cannot pass through the limit
Part is equipped with limit spring between the platform and the locating part.
Further, the power supply module includes power supply body, the wiring board connecting with the power supply body, and with institute
State the switch of circuit board electrical connection;The motor and the circuit board electrical connection.
Further, the power supply body is rechargable power supplies, is electrically connected with charge port on the wiring board.
Further, the pedestal is equipped with switch hole corresponding with the switch and the charge port and charge port
Hole.
Further, the upper end oral area of the upper housing is equipped with the upper card slot matched with the salient point, the upper housing
It is detachably connected by the clamping and disposable self-destructing vibration head assembly of the upper card slot and the salient point;Under described
The upper end oral area of shell is equipped with convex block, and the lower end oral area of the upper housing is equipped with the lower bayonet slot matched with the convex block, described
Upper housing is detachably connected by the clamping of the lower bayonet slot and the convex block and the lower case;The upper port of the pedestal
Portion is equipped with pedestal convex block, and the lower end oral area of the lower case is equipped with the pedestal card slot matched with the pedestal convex block, under described
Shell is detachably connected by the clamping of the pedestal card slot and the pedestal convex block and the pedestal.
Further, it is equipped with sealing element between the motor and the platform, offers on the sealing element for wearing
The through-hole of the shaft.
Protrusion effect of the invention are as follows: a kind of disposable self-destructing of the invention vibrates head assembly and using the component
Promote to seep instrument, by the rotation of pressure part and inner core disconnected the problem of reaching self-destruction effect, avoiding recycling, is guaranteeing human skin
While improving absorption efficiency, the health of human body of user has been ensured.
Detailed description of the invention
Fig. 1 is the pressure part and model core arrangement schematic diagram of the embodiment of the present invention 1;
Fig. 2 is the structural schematic diagram of the connector of the embodiment of the present invention 1;
Fig. 3 is the structural schematic diagram of the platform of the embodiment of the present invention 1;
Fig. 4 is the Structure explosion diagram of the embodiment of the present invention 2;
Fig. 5 is the upper housing bottom view of the embodiment of the present invention 2;
Fig. 6 is the structural schematic diagram of the embodiment of the present invention 2;
Fig. 7 is that permeability changes over time figure in experimental example of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Embodiment 1
As shown in Figure 1-3, a kind of disposable self-destructing vibration head assembly of the present embodiment is held including hollow pressure part 1
The inner surface of casting die 1 is equipped with salient point 11.
The hollow inside of pressure part 1 is equipped with an inner core 2, twists off the connection of part 3 by 4 between inner core 2 and pressure part 1;It is interior
Core 2 includes active section 21 and linkage section 22, and the upper surface of active section 21 is equipped with the micro device for only penetrating keratoderma
23, micro device 23 is nanometer chip.
Annular slot 24 is offered in the circumferential direction of linkage section 22;The cross section of the active section 21 of pressure part 1 and inner core 2 is
It is round.
It further include connector 4, the upper end of connector 4 is equipped with the buckle 41 matched with annular slot 24, and lower end is equipped with flat
Platform 42.The cross section of the linkage section 22 of inner core 2 is square, and the buckle 41 of the upper end of connector 4 is to match with linkage section 22
FFour piece type buckle.The lower end of connector 4 is equipped with connection card slot 43, and platform 42 is equipped with platform buckle 44, connector 4 and platform
42 are locked and connected by connection card slot 43 and platform card button 44.
Embodiment 2
The present embodiment is similar to Example 1, the difference is that optionally, the cross section of the linkage section 22 of inner core 2 is three
Angular, the buckle 41 of the upper end of connector 4 is the three-clove style buckle matched with linkage section 22;Micro device 23 is that nanometer is micro-
Needle.
Embodiment 3
A kind of rush of the present embodiment seeps instrument, and the disposable self-destructing including embodiment 1 vibrates head assembly, with Disposable, self-destroying
The upper housing 5 that formula vibration head assembly is detachably connected, and the lower case 6 being detachably connected with upper housing 5;Lower case 6 is fixed
On pedestal 7, power supply module, and the motor 8 being electrically connected with power supply module are equipped in pedestal 7 and lower case 6, a shaft 9
One end and motor 8 are drivingly connected, and the other end and the platform 42 of disposable self-destructing vibration head assembly offset;It is equipped in upper housing 5
Locating part 51, connector 4 are arranged in locating part 51, and platform 42 cannot pass through locating part 51, platform 42 and locating part 51 it
Between be equipped with limit spring 52.
Power supply module includes power supply body 61, the wiring board 62 connecting with power supply body 61, and is electrically connected with wiring board 62
The switch 63 connect;Motor 8 is electrically connected with wiring board 62.
Power supply body 61 is rechargable power supplies, is electrically connected with charge port 64 on wiring board 62.
Pedestal 7 is equipped with switch hole 71 corresponding with switch 63 and charge port 64 and charging oral pore 72.
The upper end oral area of upper housing 5 is equipped with the upper card slot 53 that matches with salient point 11, and upper housing 5 passes through upper card slot 53 and convex
The clamping of point 11 and disposable self-destructing vibration head assembly are detachably connected;The upper end oral area of lower case 6 is equipped with convex block 65, on
The lower end oral area of shell 5 is equipped with the lower bayonet slot 54 matched with convex block 65, and upper housing 5 passes through the clamping of lower bayonet slot 54 and convex block 65
It is detachably connected with lower case 6;The upper end oral area of pedestal 7 is equipped with pedestal convex block 73, and the lower end oral area of lower case 6 is equipped with and bottom
The pedestal card slot 66 that seat convex block 73 matches, lower case 6 are removable by the clamping of pedestal card slot 66 and pedestal convex block 73 and pedestal 7
It connects with unloading.
It is equipped with sealing element 10 between motor 8 and platform 42, the through-hole 101 for wearing shaft 9 is offered on sealing element 10.
The rush of a kind of disposable self-destructing vibration head assembly and application of the present embodiment component seeps instrument, passes through pressure part
1 and inner core 2 rotation disconnected the problem of reaching self-destruction effect, avoiding recycling, guaranteeing that human skin improves absorption efficiency
Meanwhile the health of human body of user is ensured.
Experimental example
This experiment compares the lidocaine gel of autogamy (miniature using disposable self-destructing of the present invention vibration head assembly
Set and use nanometer chip) cooperation promotees to seep instrument (A group) and rush infiltration instrument (B group) of setting nanometer chip is handled respectively directly on shaft
Transdermal absorption result after 20 seconds.
This experimental method is as follows:
Pig ear in refrigerator is taken, 800 μ m-thick of skin is taken, removes the hair on surface, until smooth.PBS (7.4) impregnate 10 minutes-
After 15 minutes, 2 parts are taken to be cut into reception tank outer rim size respectively, A group and B group act on 20s, are placed between reception tank and administration pond, 37
± 0.2 DEG C of PBS (7.4) balances 1h.With Franze diffusion cell, dosage 120mg, reception tank volume 2.5mL, practical transdermal area
0.66cm2, receiving liquid be PBS (7.4), 37 ± 0.2 DEG C of temperature, magnetic agitation 280rmp.
By Fig. 7 (wherein ◆ be A group, ■ is B group) as it can be seen that compared with A group, the transdermal effect of the lidocaine gel of B group
It is poor, and the transdermal effect of the lidocaine gel of A group is obviously improved.It is most unexpected to be that while it is using nanocrystalline
Piece, the effect of A group are substantially better than B group, illustrate that the method can significantly improve the mechanisms of nanometer chip, using with advantage.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (13)
1. a kind of disposable self-destructing vibrates head assembly, it is characterised in that: including hollow pressure part, the pressure part it is hollow
Inside is equipped with an inner core, twists off part connection by least one between the inner core and the pressure part;The inner core includes work
Make section and linkage section, the upper surface of the active section is equipped with the micro device for only penetrating keratoderma, the linkage section
Circumferential direction on offer annular slot;It further include connector, the upper end of the connector is equipped with to be matched with the annular slot
Buckle, lower end be equipped with platform.
2. a kind of disposable self-destructing according to claim 1 vibrates head assembly, it is characterised in that: the pressure part it is interior
Surface is equipped with salient point.
3. a kind of disposable self-destructing according to claim 1 vibrates head assembly, it is characterised in that: the inner core and described
By twisting off part connection described in 4 between pressure part.
4. a kind of disposable self-destructing according to claim 1 vibrates head assembly, it is characterised in that: the pressure part and institute
The cross section for stating the active section of inner core is circle.
5. a kind of disposable self-destructing according to claim 1 vibrates head assembly, it is characterised in that: the inner core it is described
The cross section of linkage section is triangle or square, and the buckle of the upper end of the connector is to match with the linkage section
Three-clove style buckle or fFour piece type buckle.
6. a kind of disposable self-destructing according to claim 1 vibrates head assembly, it is characterised in that: the micro device is
Nanometer micropin or nanometer chip.
7. a kind of disposable self-destructing according to claim 1 vibrates head assembly, it is characterised in that: under the connector
End is equipped with connection card slot, and the platform is equipped with platform and buckles, the connector and the platform pass through the connection card slot and
The platform snap lock is solidly connected.
8. a kind of rush seeps instrument, it is characterised in that: including disposable self-destructing vibration head group of any of claims 1-7
Part, the upper housing being detachably connected with disposable self-destructing vibration head assembly, and be detachably connected with the upper housing
Lower case;The lower case is fixed on the base, and is equipped with power supply module in the pedestal and the lower case, and with it is described
The motor of power supply module electrical connection, one end of a shaft are connect with the motor driven, the other end and the disposable self-destructing
The platform of vibration head assembly offsets;Locating part is equipped in the upper housing, the connector is arranged in the locating part,
And the platform cannot pass through the locating part, and limit spring is equipped between the platform and the locating part.
9. a kind of rush stated according to claim 8 seeps instrument, it is characterised in that: the power supply module includes power supply body, and described
The wiring board of power supply body connection, and the switch with the circuit board electrical connection;The motor and the circuit board electrical connection.
10. a kind of rush according to claim 9 seeps instrument, it is characterised in that: the power supply body is rechargable power supplies, described
Charge port is electrically connected on wiring board.
11. a kind of rush according to claim 10 seeps instrument, it is characterised in that: the pedestal is equipped with and the switch and institute
State the corresponding switch hole of charge port and charging oral pore.
12. a kind of rush according to claim 8 seeps instrument, it is characterised in that: the upper end oral area of the upper housing is equipped with and institute
State the upper card slot that salient point matches, clamping and the Disposable, self-destroying of the upper housing by the upper card slot and the salient point
It is detachably connected that formula vibrates head assembly;The upper end oral area of the lower case is equipped with convex block, and the lower end oral area of the upper housing is set
There are the lower bayonet slot matched with the convex block, clamping and the lower casing of the upper housing by the lower bayonet slot and the convex block
Body is detachably connected;The upper end oral area of the pedestal is equipped with pedestal convex block, the lower end oral area of the lower case be equipped with it is described
The pedestal card slot that pedestal convex block matches, the lower case by the clamping of the pedestal card slot and the pedestal convex block with it is described
Pedestal is detachably connected.
13. seeping instrument according to a kind of rush that claim 8 is stated, it is characterised in that: be equipped with sealing between the motor and the platform
Part offers the through-hole for wearing the shaft on the sealing element.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711204592.9A CN109833562B (en) | 2017-11-27 | 2017-11-27 | Disposable self-destruction type vibrating head assembly and permeation promoting instrument using same |
PCT/CN2018/112009 WO2019100901A1 (en) | 2017-11-27 | 2018-10-26 | Disposable self-destructive vibration head assembly and penetration-enhancing instrument using same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711204592.9A CN109833562B (en) | 2017-11-27 | 2017-11-27 | Disposable self-destruction type vibrating head assembly and permeation promoting instrument using same |
Publications (2)
Publication Number | Publication Date |
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CN109833562A true CN109833562A (en) | 2019-06-04 |
CN109833562B CN109833562B (en) | 2024-03-15 |
Family
ID=66631807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201711204592.9A Active CN109833562B (en) | 2017-11-27 | 2017-11-27 | Disposable self-destruction type vibrating head assembly and permeation promoting instrument using same |
Country Status (2)
Country | Link |
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CN (1) | CN109833562B (en) |
WO (1) | WO2019100901A1 (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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US20150088050A1 (en) * | 2012-06-26 | 2015-03-26 | Franklin J. Chang | Apparatus and Method for Transdermal Fluid Delivery |
CN104707242A (en) * | 2015-03-31 | 2015-06-17 | 苏州纳通生物纳米技术有限公司 | Disposable self-damage device |
CN204910479U (en) * | 2015-03-31 | 2015-12-30 | 苏州纳通生物纳米技术有限公司 | Disposable self -damage device |
CN210205599U (en) * | 2017-11-27 | 2020-03-31 | 苏州纳通生物纳米技术有限公司 | Disposable self-destruction vibrating head component and infiltration promoting instrument using same |
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US7429258B2 (en) * | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
CN202516156U (en) * | 2011-12-22 | 2012-11-07 | 邓成燕 | Electric microneedle |
WO2014002872A1 (en) * | 2012-06-26 | 2014-01-03 | 凸版印刷株式会社 | Instrument for operating fluid injector using multi-microneedle device |
CN204293679U (en) * | 2014-11-14 | 2015-04-29 | 广州梓煊美容器材有限公司 | Sewing and skin micro-needle cosmetic instrument syringe needle governor motion |
CA2999988C (en) * | 2015-09-27 | 2024-06-11 | Follica, Inc. | Needling device and drug applicator |
CN206342799U (en) * | 2016-08-11 | 2017-07-21 | 广州天龙美业化妆品有限公司 | Disposable self-destructing sewing syringe needle and sewing beauty instrument |
CN206355435U (en) * | 2016-08-30 | 2017-07-28 | 蒋志敏 | A kind of portable electric micropin |
-
2017
- 2017-11-27 CN CN201711204592.9A patent/CN109833562B/en active Active
-
2018
- 2018-10-26 WO PCT/CN2018/112009 patent/WO2019100901A1/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150088050A1 (en) * | 2012-06-26 | 2015-03-26 | Franklin J. Chang | Apparatus and Method for Transdermal Fluid Delivery |
CN104707242A (en) * | 2015-03-31 | 2015-06-17 | 苏州纳通生物纳米技术有限公司 | Disposable self-damage device |
CN204910479U (en) * | 2015-03-31 | 2015-12-30 | 苏州纳通生物纳米技术有限公司 | Disposable self -damage device |
CN210205599U (en) * | 2017-11-27 | 2020-03-31 | 苏州纳通生物纳米技术有限公司 | Disposable self-destruction vibrating head component and infiltration promoting instrument using same |
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Publication number | Publication date |
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WO2019100901A1 (en) | 2019-05-31 |
CN109833562B (en) | 2024-03-15 |
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