CN109810208A - A kind of preparation method of chitosan - Google Patents
A kind of preparation method of chitosan Download PDFInfo
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- CN109810208A CN109810208A CN201711175028.9A CN201711175028A CN109810208A CN 109810208 A CN109810208 A CN 109810208A CN 201711175028 A CN201711175028 A CN 201711175028A CN 109810208 A CN109810208 A CN 109810208A
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- chitosan
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- acidleach
- soda boiling
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Abstract
The invention discloses a kind of preparation methods of chitosan in Chitosan preparation field, comprising the following steps: ((1), crab shell carry out acidleach after crushing；(2), the sediment after the acidleach carries out soda boiling；(3), the substance after the soda boiling carries out deacetylation processing；(4), chitosan is obtained by filtration by washing in the deacetylation treated substance；The substance after sediment and soda boiling after the acidleach will carry out washing drying；The acidleach uses 5% hydrochloric acid；Chitosan is obtained by filtration by washing after carrying out acidleach, soda boiling and deacetylation processing after crushing crab shell; so that the manufacturing technology steps of Chitosan are reduced; the preparation engineering for enormously simplifying Chitosan, improves preparation efficiency, and the present invention can be used among Chitosan preparation.
Description
Technical field
The present invention relates to a kind of preparation method of chemical substance, in particular to a kind of preparation method of chitosan.
Background technique
Chitosan is also known as chitosan, is that the chitin (chitin) being widely present by nature passes through deacetylated work
With what is obtained, chemical name is Chitosan (1-4) -2- amino-B-D glucose.From 1859, Frenchman Rouget was first
After obtaining chitosan, the biological functionality and compatibility of this natural polymer, blood compatibility, safety, microbial degradation
The excellent performances such as property by all trades and professions extensive concern, medicine, food, chemical industry, cosmetics, water process, METAL EXTRACTION and recycling,
The application study of the numerous areas such as biochemical and biomedical engineering achieves major progress.For patient, chitosan reducing blood lipid, drop
The effect existing research of blood glucose is reported.Meanwhile chitosan is included in national food additive as thickener, fruit glaze agent and uses mark
Quasi- GB-2760..
Summary of the invention
The object of the present invention is to provide a kind of preparation methods of chitosan, by carrying out acidleach, soda boiling after crushing crab shell
And Chitosan is obtained by filtration in washing after deacetylation processing, so that the manufacturing technology steps of Chitosan are reduced, enormously simplifies
The preparation engineering of Chitosan, improves preparation efficiency.
, crab shell to achieve the above object, the present invention provides a kind of preparation methods of chitosan, comprising the following steps: (1)
Acidleach is carried out after crushing；(2), the sediment after the acidleach carries out soda boiling；(3), the substance after the soda boiling carries out deacetylated
Base processing；(4), chitosan is obtained by filtration by washing in the deacetylation treated substance.
Compared with prior art, the beneficial effects of the present invention are, by after crab shell is crushed carry out acidleach, soda boiling and
Chitosan is obtained by filtration in washing after deacetylation processing, so that the manufacturing technology steps of Chitosan are reduced, enormously simplifies poly- shell
The preparation engineering of sugar, improves preparation efficiency, and the present invention can be used among Chitosan preparation.
As a further improvement of the present invention, it is dry will to carry out washing for the sediment after the acidleach and the substance after soda boiling
It is dry, impurity can be further removed in this way, promote the purity of Chitosan.
As a further improvement of the present invention, the acidleach uses 5% hydrochloric acid, so that the effect of acidleach is more preferable.
As a further improvement of the present invention, hydrogen is obtained after the adjusting for the calcium chloride acid pickle progress PH that the acidleach obtains
Calcium oxide and upper liquid can be further processed waste liquid in this way, avoid waste liquor contamination environment.
As a further improvement of the present invention, the soda boiling uses 5% sodium hydroxide solution, can make soda boiling in this way
Effect is more preferable.
As a further improvement of the present invention, the soda boiling obtains lye containing albumen, and the lye containing albumen carries out PH tune
Protein and supernatant are obtained after section, the supernatant carries out the processing of FENTON reagent oxidation after carrying out biochemical treatment, then carries out
The clear liquid obtained after reverse osmosis desalination processing can recycle among for washing, and can pollute environment in this way to avoid lye, moreover it is possible to
Improve resource utilization.
As a further improvement of the present invention, the upper liquid carries out reverse osmosis desalination processing, in this way can be further
Processing upper liquid.
Detailed description of the invention
Fig. 1 is flow chart of the present invention.
Specific embodiment
The following further describes the present invention with reference to the drawings:
The preparation method of a kind of chitosan as shown in Figure 1, comprising the following steps: (1), after crab shell crushing carry out acidleach；(2),
Sediment after acidleach carries out soda boiling；(3), the substance after soda boiling carries out deacetylation processing；(4), treated for deacetylation
Chitosan is obtained by filtration by washing in substance；The substance after sediment and soda boiling after acidleach will carry out washing drying；Acidleach
Using 5% hydrochloric acid；Calcium hydroxide and upper liquid are obtained after the adjusting for the calcium chloride acid pickle progress PH that acidleach obtains；Soda boiling is adopted
With 5% sodium hydroxide solution；Soda boiling obtains lye containing albumen, and lye containing albumen obtains protein and supernatant after carrying out PH adjusting,
Supernatant carries out the processing of FENTON reagent oxidation after carrying out biochemical treatment, then the clear liquid obtain after reverse osmosis desalination processing can
It is used among washing with recycling；Upper liquid carries out reverse osmosis desalination processing.
When work, crab shell carries out acidleach with 5% hydrochloric acid after crushing and obtains calcium chloride acid pickle and sediment, sediment warp
It crosses after washing drying and is washed later with 5% sodium hydroxide solution soda boiling using deacetylation processing is carried out after washing drying
It washs and Chitosan is obtained by filtration, the lye containing albumen after soda boiling obtains supernatant after protein after carrying out PH adjusting, and supernatant passes through
Fenton reagent oxidation processes are carried out after biochemical treatment.Solution after treatment can be used for after carrying out reverse osmosis desalination processing
Among washing, calcium chloride acid pickle obtains calcium hydroxide and upper liquid, upper liquid warp let-off reverse osmosis desalination after carrying out PH adjusting
The clear liquid obtained after processing can be used among washing.
The present invention is not limited to the above embodiment, on the basis of the technical solution of the disclosure, those skilled in the art
According to disclosed technology contents, some replacements can be made to some of which technical characteristic by not needing creative labor
And deformation, these replacements and deformation are within the scope of the invention.
Claims (7)
1. a kind of preparation method of chitosan, which comprises the following steps:
(1), crab shell carries out acidleach after crushing；
(2), the sediment after the acidleach carries out soda boiling；
(3), the substance after the soda boiling carries out deacetylation processing；
(4), chitosan is obtained by filtration by washing in the deacetylation treated substance.
2. a kind of preparation method of chitosan according to claim 1, it is characterised in that: sediment after the acidleach with
And the substance after soda boiling will carry out washing drying.
3. a kind of preparation method of chitosan according to claim 1, it is characterised in that: the acidleach uses 5% salt
Acid.
4. a kind of preparation method of chitosan according to claim 2, it is characterised in that: the calcium chloride that the acidleach obtains
Calcium hydroxide and upper liquid are obtained after the adjusting of acid pickle progress PH.
5. a kind of preparation method of chitosan according to claim 1, it is characterised in that: the soda boiling uses 5% hydroxide
Sodium solution.
6. a kind of preparation method of chitosan according to claim 4, it is characterised in that: the soda boiling obtains alkali containing albumen
Liquid, the lye containing albumen obtain protein and supernatant after carrying out PH adjusting, and the supernatant carries out after carrying out biochemical treatment
FENTON reagent oxidation processing, then carry out the clear liquid obtained after reverse osmosis desalination processing can recycle for wash among.
7. a kind of preparation method of chitosan according to claim 4 or 6, it is characterised in that: the upper liquid carries out anti-
Infiltration removes salt treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711175028.9A CN109810208A (en) | 2017-11-22 | 2017-11-22 | A kind of preparation method of chitosan |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711175028.9A CN109810208A (en) | 2017-11-22 | 2017-11-22 | A kind of preparation method of chitosan |
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| Publication Number | Publication Date |
|---|---|
| CN109810208A true CN109810208A (en) | 2019-05-28 |
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ID=66601311
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| Application Number | Title | Priority Date | Filing Date |
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| CN201711175028.9A Pending CN109810208A (en) | 2017-11-22 | 2017-11-22 | A kind of preparation method of chitosan |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113402571A (en) * | 2021-05-28 | 2021-09-17 | 合肥信达膜科技有限公司 | Method for preparing chitosan oligosaccharide by membrane separation process |
-
2017
- 2017-11-22 CN CN201711175028.9A patent/CN109810208A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113402571A (en) * | 2021-05-28 | 2021-09-17 | 合肥信达膜科技有限公司 | Method for preparing chitosan oligosaccharide by membrane separation process |
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| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190528 |
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| WD01 | Invention patent application deemed withdrawn after publication |