CN109806657A - A kind of blood plasma extraction element - Google Patents
A kind of blood plasma extraction element Download PDFInfo
- Publication number
- CN109806657A CN109806657A CN201711154121.1A CN201711154121A CN109806657A CN 109806657 A CN109806657 A CN 109806657A CN 201711154121 A CN201711154121 A CN 201711154121A CN 109806657 A CN109806657 A CN 109806657A
- Authority
- CN
- China
- Prior art keywords
- blood
- cavity
- plasma
- blood plasma
- whole blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000002381 plasma Anatomy 0.000 title claims abstract description 104
- 238000000605 extraction Methods 0.000 title claims abstract description 51
- 210000004369 blood Anatomy 0.000 claims abstract description 93
- 239000008280 blood Substances 0.000 claims abstract description 93
- 238000010241 blood sampling Methods 0.000 claims abstract description 16
- 238000001914 filtration Methods 0.000 claims abstract description 16
- 238000003825 pressing Methods 0.000 claims abstract description 4
- 230000003014 reinforcing effect Effects 0.000 claims description 2
- 238000007789 sealing Methods 0.000 claims description 2
- 239000000284 extract Substances 0.000 abstract description 3
- 238000001514 detection method Methods 0.000 description 11
- 238000012123 point-of-care testing Methods 0.000 description 11
- 239000007788 liquid Substances 0.000 description 6
- 238000000926 separation method Methods 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000037303 wrinkles Effects 0.000 description 3
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000001772 blood platelet Anatomy 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/02—Filters adapted for location in special places, e.g. pipe-lines, pumps, stop-cocks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The present invention is suitable for medical instruments field, provides a kind of blood plasma extraction element, comprising: can form the cavity of negative pressure, one end of the cavity is mutually isolated whole blood extraction conduit and plasma outlet tube road；It is connected to respectively by the first check valve and second one-way valve between cavity and the whole blood extraction conduit and plasma outlet tube road；The end of whole blood extraction conduit is blood sampling end；The end in plasma outlet tube road is blood plasma output end, be provided in plasma outlet tube road can be by Whole Blood Filtration blood plasma filter device；When cavity forms negative pressure, whole blood can be collected in the cavity through the blood sampling end；When pressing to cavity, the chamber intracorporal Whole Blood Filtration can be discharged after blood plasma through the blood plasma output end.The blood plasma extraction element can disposably complete acquisition whole blood and export blood plasma, and not need that plasma sample can be obtained by other haemocyte separate apparatus, and it is convenient to operate, and can accurately and quantitatively extract blood plasma, and low in cost, safe and reliable.
Description
Technical field
The invention belongs to medical instruments field more particularly to a kind of blood plasma extraction elements.
Background technique
In clinical examination, carrying out screening to disease by blood biochemistry detection is a common disorder in screening method.Blood
Liquid is by blood plasma and is suspended in haemocyte therein and forms, and haemocyte includes red blood cell, leucocyte and blood platelet.Blood plasma is blood
Liquid component, contain moisture, plasma protein, electrolyte, nutrient, enzyme, steroids, cholesterol and other important compositions
Part.The sample of blood biochemistry detection is usually blood plasma and/or serum, that is, needs the blood that will be drawn into separate, obtain blood
The blood plasma and/or serum sample of biochemistry detection.
In the prior art, the blood of patient is usually extracted by medical staff and seals packing or refrigeration, then send blood back to
Liquid control laboratory is detected, therefore the period tested is longer, is unfavorable for the timely diagnosis direction of medication usage etc. to disease.And POCT
(point-of-care testing, real-time test) refers to and carries out clinical detection (bedside detection, bedside beside patient
Testing), it is not necessarily clinical examination teacher usually to carry out.Existing POCT is that the blood being drawn into directly is added to POCT
It is detected on chip, but due to the ratio of everyone blood plasma and/or serum difference, so it is same amount of to extract different people
Blood, the ratio of blood plasma and/or serum obtained after centrifuge separation is also different, therefore directly toward adding on POCT chip
Blood, which carries out detection, will have that sample-adding amount is inaccurate, and then the problem of influence the accuracy of testing result, this is equally unfavorable for
To the Accurate Diagnosis direction of medication usage etc. of disease.
However, the blood being drawn into can be carried out by centrifuge isolated to improve the accuracy of POCT sample-adding
Serum and/or blood plasma are then added on POCT chip, but centrifuge is generally placed upon in laboratory the use that is exclusively managed by a specially-assigned person, and
And volume is larger, it has not been convenient to move away to bedside and detect；Or by blood cell separation device, electricity drives washed corpuscles, obtains blood
Clear and/or blood plasma, but the time at high cost and isolated of this separation is long.
Summary of the invention
The embodiment of the invention provides a kind of blood plasma extraction elements, it is intended to it solves in the prior art, it is straight on POCT chip
It connects and heals liquid and detected and be not easy to there are sample-adding amount is inaccurate, and using other haemocyte separate apparatus washed corpuscles
Placement, and problem at high cost, that the time is long.
The embodiments of the present invention are implemented as follows, a kind of blood plasma extraction element, comprising:
The cavity of negative pressure can be formed, one end of the cavity is mutually isolated whole blood extraction conduit and plasma outlet tube
Road；
Pass through the first check valve and second between the cavity and the whole blood extraction conduit and plasma outlet tube road respectively
Check valve connection；
The end of the whole blood extraction conduit is blood sampling end；
The end in the plasma outlet tube road is blood plasma output end, and being provided in the plasma outlet tube road can be by whole blood mistake
Filter is the filter device of blood plasma；
When the cavity forms negative pressure, whole blood can be collected in the cavity through the blood sampling end；
When pressing to the cavity, the chamber intracorporal Whole Blood Filtration can be arranged after blood plasma through the blood plasma output end
Out.
Blood plasma extraction element provided in an embodiment of the present invention can be complete by the acquisition of blood sampling end when its cavity forms negative pressure
Blood, and to its cavity press when, can by the Whole Blood Filtration of acquisition be blood plasma after export, operate it is very convenient, do not need by
Other haemocyte separate apparatus, so that it may plasma sample is directly obtained, it is low in cost, that is, it solves in the prior art in POCT
Liquid is directly healed on chip to be detected and thin there are sample-adding amount is inaccurate, and using other haemocyte separate apparatus separation blood
Born of the same parents are not easy to dispose, and problem at high cost, that the time is long.
Detailed description of the invention
Fig. 1 is the structural schematic diagram for the blood plasma extraction element that first embodiment of the invention provides；
Fig. 2 is the structural schematic diagram for the blood plasma extraction element that second embodiment of the invention provides；
Fig. 3 is the structural schematic diagram for the blood plasma extraction element that third embodiment of the invention provides.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
Blood plasma extraction element provided in an embodiment of the present invention can be complete by the acquisition of blood sampling end when its cavity forms negative pressure
Blood, and to its cavity press when, can by the Whole Blood Filtration of acquisition be blood plasma after export, operate it is very convenient, do not need by
Other haemocyte separate apparatus, so that it may plasma sample is directly obtained, it is low in cost.
Referring to Fig. 1~3, blood plasma extraction element provided in an embodiment of the present invention includes: the cavity 1 that can form negative pressure, cavity 1
One end be mutually isolated whole blood extraction conduit 2 and plasma outlet tube road 3；Cavity 1 and whole blood extraction conduit 2 and blood plasma export
It is connected to respectively by the first check valve 4 with second one-way valve 5 between pipeline 3；Wherein, the end of whole blood extraction conduit 2 is blood sampling
End 21；The end in plasma outlet tube road 3 is blood plasma output end 31, and being provided in plasma outlet tube road 3 can be blood by Whole Blood Filtration
The filter device 6 of slurry；When cavity 1 forms negative pressure, end 21 that whole blood can be taken a blood sample is collected in cavity 1；It presses when to cavity 1
When, the Whole Blood Filtration in cavity 1 can be discharged after blood plasma through blood plasma output end 31.
Blood plasma extraction element provided in an embodiment of the present invention can be complete by the acquisition of blood sampling end when its cavity forms negative pressure
Blood, and to its cavity press when, can by the Whole Blood Filtration of acquisition be blood plasma after export, operate it is very convenient, do not need by
Other haemocyte separate apparatus, so that it may plasma sample is directly obtained, it is low in cost, that is, it solves in the prior art in POCT
Liquid is directly healed on chip to be detected and thin there are sample-adding amount is inaccurate, and using other haemocyte separate apparatus separation blood
Born of the same parents are not easy to dispose, and problem at high cost, that the time is long.
As the first embodiment of the present invention, referring to Fig. 1, be equipped in the cavity 1 of the blood plasma extraction element in cavity 1
Wall sealing cooperation, can push and pull the plunger 7 of movement.Plunger 7 is pulled, so that cavity 1 forms negative pressure, end 21 that whole blood can be taken a blood sample is adopted
Collect in cavity 1；Plunger 7 is pushed to press to cavity 1, so that Whole Blood Filtration in cavity 1 is after blood plasma through blood plasma output end 31
Discharge.
It in an embodiment of the present invention, can be first defeated by whole blood extraction conduit 2 and/or blood plasma during drawing blood detection
Pipeline 3 penetrates in the skin histology of patient out, and the end of hand-held plunger 7, plunger 7 is pulled out, at this point, whole blood extraction conduit
Air in 2 is extracted, and forms negative pressure, and whole blood is under conditions of pressure difference, as blood sampling end 21 enters whole blood extraction conduit 2, and
The first check valve 4 is opened, the opening via the first check valve 4 enters in cavity 1；After being drawn into the whole blood of sufficient amount, pass through
Plunger 7 is pushed to apply pressure to cavity 1, the whole blood being now in cavity 1 can open second under the action of the pressure of application
Check valve 5, and entered in filter device 6 via the opening of second one-way valve 5, after filter device 6 is filtered into blood plasma, then
It is discharged via blood plasma output end 31.
In a preferred embodiment of the invention, cavity 1 is equipped with the limit knot of the push-and-pull movement for limiting plunger 7
Structure (not shown).Specifically, position limiting structure can be set at handle 71 of the other end close to plunger 7 of cavity 1, to prevent
Only plunger 7 is completely pulled out of in cavity 1 during pulling.Certainly, which also can be set in plunger 7 close to hand
One end of handle 71 can prevent plunger 7 from continuing to move out when plunger 7 is drawn to the position limiting structure.
As the second embodiment of the present invention, referring to fig. 2, which includes a negative pressure generating device, wherein
The negative pressure generating device can be the flexible suction ball 8 for being installed on the other end of cavity 1.
In an embodiment of the present invention, during drawing blood detection, it can first squeeze flexible suction ball 8 and cavity 1, blood plasma is discharged
Air some or all of in output channel 3 and flexible suction ball 8 forms negative pressure, then by whole blood extraction conduit at this time in cavity 1
2 and/or plasma outlet tube road 3 penetrate in the skin histology of patient, and flexible suction ball 8 is unclamped, at this point, effect of the whole blood in pressure difference
Under whole blood extraction conduit 2 can be entered by blood sampling end 21, and open the first check valve 4, via the first check valve 4 opening into
Enter in cavity 1；After being drawn into the whole blood of sufficient amount, flexible suction ball 8 is squeezed again, is pressed to cavity 1, so that into cavity 1
Interior whole blood opens second one-way valve 5, and enters in filter device 6 via the opening of second one-way valve 5, by filter device 6
After being filtered into blood plasma, it is discharged from blood plasma output end 31.
In an embodiment of the present invention, flexible suction ball 8 can be made of rubber material, rubber high resilience, in very little
Larger deformation can be generated under external force, remove resilient after external force.
As the third embodiment of the present invention, referring to Fig. 3, which can be for set on the lateral wall of cavity 1
Bellows 9.Bellows 9 can be the tubular elastomeric sensing element connected into foldable wrinkle piece along folding retractable direction.
In an embodiment of the present invention, during drawing blood detection, by whole blood extraction conduit 2 and/or plasma outlet tube
Road 3 penetrates in the skin histology of patient, and compress bellows 9 fold up its wrinkle piece, can move out with piston 10, this
When, the air in cavity 1 is extracted, and forms negative pressure, and whole blood enters whole blood extraction tube under the action of pressure difference, from blood sampling end 21
Road 2, and the first check valve 4 is opened, entered inside cavity 1 by the opening of the first check valve 4；When the whole blood for being drawn into sufficient amount
Afterwards, unclamping bellows 9 extends its wrinkle piece, and piston 10 is under the drive of the stretching routine of bellows 9 at this time, to cavity
Pressure in 1 so that the whole blood in cavity 1 can open second one-way valve 5, and enters via the opening of second one-way valve 5
In filter device 6, after filter device 6 is filtered into blood plasma, it is discharged from blood plasma output end 31.
The blood plasma extraction element that above-mentioned first, second, third embodiment provides can lead to when its cavity forms negative pressure
Blood sampling end acquisition whole blood is crossed, and when pressing to its cavity, can be by the Whole Blood Filtration of acquisition to be exported after blood plasma, operation is very just
Victory is not needed by other haemocyte separate apparatus, so that it may plasma sample is directly obtained, it is low in cost, and improve POCT
It is loaded accuracy.
In an embodiment of the present invention, above-mentioned filter device 6 is blood filter membrane, can farthest inhibit haemolysis, in short-term
It is interior to fast implement separating and filtering red blood cell, and stability and homogeneity are good, can rapidly be realized and be isolated by blood filter membrane
Blood plasma and haemocyte, blood plasma can be discharged by blood filter membrane, and haemocyte is then trapped on the blood filtration membrane, and isolated cost is low, and
Operation is simple.
In an embodiment of the present invention, filter device 6 can be set before or after second one-way valve 5.Specifically,
Before filter device 6 is set to second one-way valve 5, then the whole blood in cavity 1 is being filtered into blood plasma by filter device 6
Afterwards, it is discharged using second one-way valve 5, blood plasma output end 31.After filter device 6 is set to second one-way valve 5, then it is in
Whole blood in cavity 1 is flowed into filter device 6 via second one-way valve 5 to be filtered, and blood plasma is discharged from blood plasma output end 31.
In a preferred embodiment of the invention, the quarter for showing botal blood volume collected can be set on cavity 1
Spend ruler 11.By the scale of graduated scale 11, medical staff can blood volume that is clear, being visually observed that current extraction, so as to
When the blood volume that extracts of control but also quickly completed blood so that the plasma volume of discharge can not only meet the usage amount of blood biochemistry detection
Slurry extracts, and reduces the blood drawing feeling of pain and psychological pressure of patient.But also be conducive to accurately quantify, improve the accuracy of detection.
In a preferred embodiment of the invention, which is a pen type structure, compact, light
Just, it carries, use convenient for medical staff.
In a preferred embodiment of the invention, the engagement of whole blood extraction conduit 2 and plasma outlet tube road 3 and cavity 1
Position is equipped with reinforcing rib (not shown), strong to improve whole blood extraction conduit 2 and plasma outlet tube road 3 and the engagement of cavity 1
Degree reduces needle tubing and occurs the risk being broken in use.
In an embodiment of the present invention, which can use Shooting Technique one-pass molding, disposably to make
Product avoids the cross contamination of blood, high safety and reliability.
Blood plasma extraction element provided in an embodiment of the present invention can be complete by the acquisition of blood sampling end when its cavity forms negative pressure
Blood, and to its cavity press when, can by the Whole Blood Filtration of acquisition be blood plasma after export, operate it is very convenient, do not need by
Other haemocyte separate apparatus, so that it may plasma sample is directly obtained, it is low in cost.It is whole device compact, light, it can
It carries, facilitates the use of personnel, mitigate the workload of medical staff, and use one-time formed technique, be simple to manufacture；One
Secondary property use is more safe and reliable.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (9)
1. a kind of blood plasma extraction element characterized by comprising
The cavity of negative pressure can be formed, one end of the cavity is mutually isolated whole blood extraction conduit and plasma outlet tube road；
It is unidirectional by the first check valve and second respectively between the cavity and the whole blood extraction conduit and plasma outlet tube road
Valve connection；
The end of the whole blood extraction conduit is blood sampling end；
The end in the plasma outlet tube road is blood plasma output end, and being provided in the plasma outlet tube road can be by Whole Blood Filtration
The filter device of blood plasma；
When the cavity forms negative pressure, whole blood can be collected in the cavity through the blood sampling end；
When pressing to the cavity, the chamber intracorporal Whole Blood Filtration can be discharged after blood plasma through the blood plasma output end.
2. blood plasma extraction element as described in claim 1, which is characterized in that be equipped in the cavity and the cavity inner wall
Sealing cooperation, can push and pull the plunger of movement；
The plunger is pulled, so that the cavity forms negative pressure, whole blood can be collected in the cavity through the blood sampling end；
Push the plunger to press to the cavity so that the intracorporal Whole Blood Filtration of the chamber be blood plasma after exported through the blood plasma
End discharge.
3. blood plasma extraction element as described in claim 1, which is characterized in that the blood plasma extraction element is generated including a negative pressure
Device；
The negative pressure generating device is the flexible suction ball device for being installed on the other end of the cavity.
4. blood plasma extraction element as described in claim 1, which is characterized in that the negative pressure generating device is set on the cavity
Lateral wall bellows.
5. the blood plasma extraction element as described in claim 1,2,3 or 4, which is characterized in that the filter device is set to described
Before or after second one-way valve.
6. blood plasma extraction element as described in claim 1, which is characterized in that be provided on the cavity and acquired for showing
Botal blood volume graduated scale.
7. blood plasma extraction element as described in claim 1, which is characterized in that the blood plasma extraction element is a pen type structure.
8. blood plasma extraction element as claimed in claim 2, which is characterized in that the cavity is equipped with for limiting the plunger
Push-and-pull movement position limiting structure.
9. blood plasma extraction element as described in claim 1, which is characterized in that the whole blood extraction conduit and plasma outlet tube road
Reinforcing rib is equipped with the junction of the cavity.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711154121.1A CN109806657A (en) | 2017-11-20 | 2017-11-20 | A kind of blood plasma extraction element |
| PCT/CN2018/115941 WO2019096259A1 (en) | 2017-11-20 | 2018-11-16 | Blood plasma extraction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711154121.1A CN109806657A (en) | 2017-11-20 | 2017-11-20 | A kind of blood plasma extraction element |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109806657A true CN109806657A (en) | 2019-05-28 |
Family
ID=66538925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711154121.1A Pending CN109806657A (en) | 2017-11-20 | 2017-11-20 | A kind of blood plasma extraction element |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN109806657A (en) |
| WO (1) | WO2019096259A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110693505A (en) * | 2019-10-16 | 2020-01-17 | 陈玟荪 | Plasma collection method and device for clinical medicine |
| CN111413186A (en) * | 2020-04-10 | 2020-07-14 | 芜湖森爱驰生物科技有限公司 | Blood separation ration application of sample ware |
| CN116159435A (en) * | 2023-04-24 | 2023-05-26 | 山东和康源生物育种股份有限公司 | Immune serum impurity infiltration filtering device and infiltration filtering method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09143081A (en) * | 1995-06-09 | 1997-06-03 | Toyobo Co Ltd | Plasma separation filter, separation of plasma using the filter and plasma separation apparatus |
| CN104519976A (en) * | 2012-08-09 | 2015-04-15 | 霍夫曼-拉罗奇有限公司 | Multi-part device for extracting plasma from blood |
| WO2016073415A2 (en) * | 2014-11-04 | 2016-05-12 | Wainamics, Inc. | Microscale plasma separator |
| CN207520722U (en) * | 2017-11-20 | 2018-06-22 | 李泉 | A kind of blood plasma extraction element |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6659288B2 (en) * | 2000-05-16 | 2003-12-09 | Fuji Photo Film Co., Ltd. | Plasma- or serum-collecting device |
| WO2014024066A1 (en) * | 2012-08-08 | 2014-02-13 | Koninklijke Philips N.V. | Method and apparatus for separating plasma from blood for bilirubin level estimation. |
| MX368793B (en) * | 2013-04-15 | 2019-10-16 | Becton Dickinson Co | Biological fluid collection device and biological fluid separation and testing system. |
| CN106108920A (en) * | 2016-08-23 | 2016-11-16 | 郭小兵 | A kind of negative pressure leaching formula sampled plasma device being applicable to medical experiment |
-
2017
- 2017-11-20 CN CN201711154121.1A patent/CN109806657A/en active Pending
-
2018
- 2018-11-16 WO PCT/CN2018/115941 patent/WO2019096259A1/en active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09143081A (en) * | 1995-06-09 | 1997-06-03 | Toyobo Co Ltd | Plasma separation filter, separation of plasma using the filter and plasma separation apparatus |
| CN104519976A (en) * | 2012-08-09 | 2015-04-15 | 霍夫曼-拉罗奇有限公司 | Multi-part device for extracting plasma from blood |
| WO2016073415A2 (en) * | 2014-11-04 | 2016-05-12 | Wainamics, Inc. | Microscale plasma separator |
| CN207520722U (en) * | 2017-11-20 | 2018-06-22 | 李泉 | A kind of blood plasma extraction element |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110693505A (en) * | 2019-10-16 | 2020-01-17 | 陈玟荪 | Plasma collection method and device for clinical medicine |
| CN110693505B (en) * | 2019-10-16 | 2022-02-18 | 陈玟荪 | Plasma collection method and device for clinical medicine |
| CN111413186A (en) * | 2020-04-10 | 2020-07-14 | 芜湖森爱驰生物科技有限公司 | Blood separation ration application of sample ware |
| CN116159435A (en) * | 2023-04-24 | 2023-05-26 | 山东和康源生物育种股份有限公司 | Immune serum impurity infiltration filtering device and infiltration filtering method thereof |
| CN116159435B (en) * | 2023-04-24 | 2023-06-20 | 山东和康源生物育种股份有限公司 | Immune serum impurity infiltration filtering device and infiltration filtering method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019096259A1 (en) | 2019-05-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2909359C (en) | Biological fluid collection device and biological fluid separation and testing system | |
| JP6193474B2 (en) | Biological fluid collection and transfer device and biological fluid separation and inspection system | |
| US20180049686A1 (en) | Biological Fluid Separation Device and Biological Fluid Separation and Testing System | |
| CN104107561B (en) | Biofluid separator and biofluid separation and checking system | |
| CN207520722U (en) | A kind of blood plasma extraction element | |
| CN104155435B (en) | Biofluid separator and biofluid separation and checking system | |
| CN109806657A (en) | A kind of blood plasma extraction element | |
| CN203898317U (en) | Biological fluid delivering device, biological fluid sampling system and biological fluid separating and testing system | |
| CN201642046U (en) | Blood sampling device for testing | |
| CN106108920A (en) | A kind of negative pressure leaching formula sampled plasma device being applicable to medical experiment | |
| CN109157228A (en) | Blood collection tube for instant serum separation | |
| CN212513920U (en) | Blood separation ration application of sample ware | |
| CN213309769U (en) | Blood taking needle for medical examination capable of detecting HIV antibody | |
| CN207708234U (en) | It removes haemocyte in drainage-fluid and assists the negative pressure filtration device of component quantifying | |
| CN209529144U (en) | Venous blood sample collection needle and blood sampling group set | |
| CN206166928U (en) | Negative pressure suction filtration formula plasma collection system suitable for medical test | |
| CN204630775U (en) | A kind of clinical laboratory sampler | |
| KR102518189B1 (en) | All-in-one antigen-antibody test kit using a non-rigid body fluid sample collection structure | |
| CN221925741U (en) | Urine sample collecting and processing device for nucleic acid detection | |
| CN202699151U (en) | Hemostix | |
| CN219089314U (en) | Pregnant mare plasma high-efficient extraction element | |
| CN214048831U (en) | Liquid sampling device and apparatus, and sampling head or syringe for liquid sampling device | |
| CN202903573U (en) | Serum separation storage device | |
| CN201524095U (en) | Quantitative extractor for bone marrow | |
| CN209661664U (en) | A kind of disposable binary channels blood taking needle |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |