CN221925741U - Urine sample collecting and processing device for nucleic acid detection - Google Patents
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- CN221925741U CN221925741U CN202323394704.5U CN202323394704U CN221925741U CN 221925741 U CN221925741 U CN 221925741U CN 202323394704 U CN202323394704 U CN 202323394704U CN 221925741 U CN221925741 U CN 221925741U
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- 210000002700 urine Anatomy 0.000 title claims abstract description 115
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 25
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 25
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 25
- 238000001514 detection method Methods 0.000 title claims abstract description 15
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229910052782 aluminium Inorganic materials 0.000 claims abstract description 7
- 238000007789 sealing Methods 0.000 claims description 11
- 238000000605 extraction Methods 0.000 abstract description 4
- 230000007774 longterm Effects 0.000 abstract description 4
- 238000012360 testing method Methods 0.000 description 16
- 241000700605 Viruses Species 0.000 description 6
- 238000010586 diagram Methods 0.000 description 4
- 239000000243 solution Substances 0.000 description 3
- 239000012528 membrane Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000003761 preservation solution Substances 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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Abstract
本实用新型涉及一种用于核酸检测的尿液样本采集与处理装置,所属样本采集处理技术领域,包括尿液收集管,所述的尿液收集管下端设有与尿液收集管呈一体化连通的下通管,所述的下通管下端设有与下通管相粘合的铝膜,所述的尿液收集管内设有与尿液收集管相活动式嵌套的推杆件,所述的尿液收集管下端设有一次性吸头,所述的一次性吸头与尿液收集管间设有与下通管、一次性吸头相插嵌连接固定的尿液过滤柱。具有结构紧凑、省时省力和样本提取便捷的特点。解决了尿液样本核酸进行长时间保存和运输的问题。确保尿液样本进行核酸检测的准确性。
The utility model relates to a urine sample collection and processing device for nucleic acid detection, belonging to the field of sample collection and processing technology, including a urine collection tube, the lower end of the urine collection tube is provided with a down pipe that is integrated with the urine collection tube, the lower end of the down pipe is provided with an aluminum film bonded to the down pipe, the urine collection tube is provided with a push rod that is movably nested with the urine collection tube, the lower end of the urine collection tube is provided with a disposable suction head, and a urine filter column that is plugged and connected and fixed with the down pipe and the disposable suction head is provided between the disposable suction head and the urine collection tube. It has the characteristics of compact structure, time-saving and labor-saving, and convenient sample extraction. It solves the problem of long-term storage and transportation of urine sample nucleic acid. It ensures the accuracy of nucleic acid detection of urine samples.
Description
技术领域Technical Field
本实用新型涉及样本采集处理技术领域,具体涉及一种用于核酸检测的尿液样本采集与处理装置。The utility model relates to the technical field of sample collection and processing, and in particular to a urine sample collection and processing device for nucleic acid detection.
背景技术Background Art
核酸检测一般指核酸检测法,主要用于检测体内是否有病毒的存在。核酸检测法检测的物质一般是病毒的核酸,通过受检者的呼吸道标本、血液标本或者粪便标本等检测是否有外来入侵的病毒的核酸,来判断是否感染病毒,如果检测结果为阴性,大多表明没有感染病毒;如果检测结果为阳性,可能已经感染病毒或者出现假阳性的症状,一般需要再次进行相关检查。Nucleic acid testing generally refers to nucleic acid testing methods, which are mainly used to detect the presence of viruses in the body. The substance detected by the nucleic acid testing method is generally the nucleic acid of the virus. The nucleic acid of the invading virus is detected in the respiratory specimens, blood specimens or fecal specimens of the subject to determine whether the virus is infected. If the test result is negative, it mostly indicates that the virus is not infected; if the test result is positive, the virus may have been infected or false positive symptoms have occurred, and relevant tests are generally required again.
尿液检查是临床上常用的检测方法,在进行尿液检测的时候,需要对尿液进行取样,在日常检测中,通常是采集中段尿进行检验的。但是在常见的采集尿液的方式,通常是通过一次性的收集盒进行收集尿液然后再将收集盒中的尿液导入至试管中收存。Urine testing is a commonly used detection method in clinical practice. When conducting urine testing, urine samples need to be collected. In daily testing, midstream urine is usually collected for testing. However, in the common way of collecting urine, urine is usually collected through a disposable collection box and then the urine in the collection box is introduced into a test tube for storage.
发明内容Summary of the invention
本实用新型主要解决现有技术中存在的不足,提供了一种用于核酸检测的尿液样本采集与处理装置,其具有结构紧凑、省时省力和样本提取便捷的特点。解决了尿液样本核酸进行长时间保存和运输的问题。确保尿液样本进行核酸检测的准确性。The utility model mainly solves the deficiencies in the prior art and provides a urine sample collection and processing device for nucleic acid detection, which has the characteristics of compact structure, time-saving and labor-saving, and convenient sample extraction. It solves the problem of long-term storage and transportation of urine sample nucleic acid and ensures the accuracy of nucleic acid detection of urine samples.
本实用新型的上述技术问题主要是通过下述技术方案得以解决的:The above technical problems of the utility model are mainly solved by the following technical solutions:
一种用于核酸检测的尿液样本采集与处理装置,包括尿液收集管,所述的尿液收集管下端设有与尿液收集管呈一体化连通的下通管,所述的下通管下端设有与下通管相粘合的铝膜,下通管在孔未使用时覆铝膜密封。所述的尿液收集管内设有与尿液收集管相活动式嵌套的推杆件,所述的尿液收集管下端设有一次性吸头,所述的一次性吸头与尿液收集管间设有与下通管、一次性吸头相插嵌连接固定的尿液过滤柱。尿液过滤柱内部容量约1~2mL,中间含过滤膜,尿液过滤柱内的过滤膜孔径为2~30um,A urine sample collection and processing device for nucleic acid testing, comprising a urine collecting tube, wherein the lower end of the urine collecting tube is provided with a down pipe which is integrally connected with the urine collecting tube, and the lower end of the down pipe is provided with an aluminum film which is bonded to the down pipe, and the down pipe is sealed with the aluminum film when the hole is not in use. The urine collecting tube is provided with a push rod which is movably nested with the urine collecting tube, and the lower end of the urine collecting tube is provided with a disposable pipette tip, and a urine filter column which is inserted and fixedly connected with the down pipe and the disposable pipette tip is provided between the disposable pipette tip and the urine collecting tube. The internal capacity of the urine filter column is about 1 to 2 mL, and a filter membrane is contained in the middle. The pore size of the filter membrane in the urine filter column is 2 to 30 um.
作为优选,所述的推杆件包括连杆,所述的连杆下端设有与尿液收集管相活动式嵌套的橡胶活塞。推杆件与一次性注射器推杆结构功能一致。Preferably, the push rod member comprises a connecting rod, and a rubber piston movably nested with the urine collection tube is provided at the lower end of the connecting rod. The push rod member has the same structure and function as the push rod of the disposable syringe.
作为优选,所述的连杆上端设有与连杆呈一体化且直径大于尿液收集管的压盘。Preferably, the upper end of the connecting rod is provided with a pressure plate which is integrated with the connecting rod and has a diameter larger than that of the urine collection tube.
作为优选,所述的尿液过滤柱上端设有与尿液过滤柱相外螺纹式套接的上密封帽,密封尿液过滤柱的上通孔。所述的尿液过滤柱下端设有与尿液过滤柱相内螺纹式套接的下密封塞。密封尿液过滤柱的下通孔。Preferably, the upper end of the urine filter column is provided with an upper sealing cap which is externally threadedly sleeved with the urine filter column to seal the upper through hole of the urine filter column. The lower end of the urine filter column is provided with a lower sealing plug which is internally threadedly sleeved with the urine filter column to seal the lower through hole of the urine filter column.
作为优选,所述的尿液收集管上部设有外螺纹槽,所述的尿液收集管上端设有与外螺纹槽相套接固定的管盖。管盖用于收集尿液至尿液收集管后密封用。Preferably, the upper part of the urine collecting tube is provided with an external thread groove, and the upper end of the urine collecting tube is provided with a tube cover which is sleeved and fixed with the external thread groove. The tube cover is used for sealing after collecting urine into the urine collecting tube.
作为优选,所述的尿液收集管外圆壁上设有刻度值。尿液收集管带刻度,可直立放置,容量10~100mL。Preferably, the outer wall of the urine collection tube is provided with scale values. The urine collection tube is provided with scales, can be placed upright, and has a capacity of 10 to 100 mL.
本实用新型能够达到如下效果:The utility model can achieve the following effects:
本实用新型提供了一种用于核酸检测的尿液样本采集与处理装置,与现有技术相比较,具有结构紧凑、省时省力和样本提取便捷的特点。解决了尿液样本核酸进行长时间保存和运输的问题。确保尿液样本进行核酸检测的准确性。The utility model provides a urine sample collection and processing device for nucleic acid detection, which has the characteristics of compact structure, time-saving and labor-saving, and convenient sample extraction compared with the prior art. It solves the problem of long-term storage and transportation of urine sample nucleic acid and ensures the accuracy of nucleic acid detection of urine samples.
附图说明BRIEF DESCRIPTION OF THE DRAWINGS
图1是本实用新型的结构示意图。Fig. 1 is a schematic structural diagram of the utility model.
图2是本实用新型中的推杆件的结构示意图。FIG. 2 is a schematic structural diagram of a push rod member in the present utility model.
图3是本实用新型中的收集尿液的结构示意图。FIG. 3 is a schematic diagram of the structure of collecting urine in the present invention.
图4是本实用新型中的尿液样本保存和运输的结构示意图。FIG. 4 is a schematic diagram of the structure of urine sample storage and transportation in the present invention.
图中:尿液收集管1,推杆件2,外螺纹槽3,刻度值4,下通管5,铝膜6,尿液过滤柱7,一次性吸头8,压盘9,连杆10,橡胶活塞11,管盖12,上密封帽13,下密封塞14。In the figure: urine collection tube 1, push rod 2, external thread groove 3, scale value 4, lower through tube 5, aluminum film 6, urine filter column 7, disposable suction head 8, pressure plate 9, connecting rod 10, rubber piston 11, tube cover 12, upper sealing cap 13, lower sealing plug 14.
具体实施方式DETAILED DESCRIPTION
下面通过实施例,并结合附图,对本实用新型的技术方案作进一步具体的说明。The technical solution of the utility model is further specifically described below through embodiments and in conjunction with the accompanying drawings.
实施例:如图1-4所示,一种用于核酸检测的尿液样本采集与处理装置,包括尿液收集管1,尿液收集管1外圆壁上设有刻度值4。尿液收集管1下端设有与尿液收集管1呈一体化连通的下通管5,下通管5下端设有与下通管5相粘合的铝膜6,尿液收集管1上部设有外螺纹槽3,尿液收集管1上端设有与外螺纹槽3相套接固定的管盖12。尿液收集管1内设有与尿液收集管1相活动式嵌套的推杆件2,推杆件2包括连杆10,连杆10下端设有与尿液收集管1相活动式嵌套的橡胶活塞11。连杆10上端设有与连杆10呈一体化且直径大于尿液收集管1的压盘9。尿液收集管1下端设有一次性吸头8,一次性吸头8与尿液收集管1间设有与下通管5、一次性吸头8相插嵌连接固定的尿液过滤柱7,尿液过滤柱7上端设有与尿液过滤柱7相外螺纹式套接的上密封帽13,尿液过滤柱7下端设有与尿液过滤柱7相内螺纹式套接的下密封塞14。Embodiment: As shown in Figures 1-4, a urine sample collection and processing device for nucleic acid detection includes a urine collection tube 1, and a scale value 4 is provided on the outer circular wall of the urine collection tube 1. A lower through pipe 5 is provided at the lower end of the urine collection tube 1, which is connected to the urine collection tube 1 in an integrated manner, and an aluminum film 6 is provided at the lower end of the lower through pipe 5, which is bonded to the lower through pipe 5. An external thread groove 3 is provided at the upper part of the urine collection tube 1, and a tube cover 12 is provided at the upper end of the urine collection tube 1, which is sleeved and fixed to the external thread groove 3. A push rod member 2 is provided in the urine collection tube 1, which is movably nested with the urine collection tube 1. The push rod member 2 includes a connecting rod 10, and a rubber piston 11 is provided at the lower end of the connecting rod 10, which is movably nested with the urine collection tube 1. A pressure plate 9 is provided at the upper end of the connecting rod 10, which is integrated with the connecting rod 10 and has a diameter larger than that of the urine collection tube 1. A disposable suction head 8 is provided at the lower end of the urine collection tube 1, and a urine filter column 7 is provided between the disposable suction head 8 and the urine collection tube 1, which is plugged and connected with the lower through pipe 5 and the disposable suction head 8, and an upper sealing cap 13 is provided at the upper end of the urine filter column 7, which is externally threadedly sleeved with the urine filter column 7, and a lower sealing plug 14 is provided at the lower end of the urine filter column 7, which is internally threadedly sleeved with the urine filter column 7.
工作原理:患者收集尿液样本于尿液收集管1中,使用管盖12密封,交由专业人员或自行进行后续处理。接着将带尿液样本的尿液收集管1倒置,撕去下通管5处的铝膜6,将尿液过滤柱7与下通管5插接,然后正置尿液收集管1,打开管盖12,将推杆件2插入尿液收集管1,此时取尿液样本保存试管,通过推杆件2按压过滤尿液样本,至尿液样本完全滤过并保持至试管中。Working principle: The patient collects urine samples in the urine collection tube 1, seals it with the tube cover 12, and hands it over to professionals or handles it by himself. Then, turn the urine collection tube 1 with the urine sample upside down, tear off the aluminum film 6 at the lower tube 5, plug the urine filter column 7 into the lower tube 5, and then put the urine collection tube 1 upright, open the tube cover 12, and insert the push rod 2 into the urine collection tube 1. At this time, take the urine sample to store the test tube, and press the push rod 2 to filter the urine sample until the urine sample is completely filtered and kept in the test tube.
将一次性吸头8插入尿液过滤柱7下端通孔,提拉推杆件2,吸取另外配置的样本保存液或裂解液至充满尿液过滤柱7。接着拔去一次性吸头8,使用下密封塞14密封尿液过滤柱7下通孔,然后尿液过滤柱7与下通管5脱离,使用上密封帽13密封尿液过滤柱7上通孔。含尿脱落细胞的尿液过滤柱7即可进行长时间的常温保存和运输,待后续检测。Insert the disposable suction tip 8 into the through hole at the lower end of the urine filter column 7, pull up the push rod 2, and suck the separately configured sample preservation solution or lysis solution until the urine filter column 7 is filled. Then remove the disposable suction tip 8, use the lower sealing plug 14 to seal the lower through hole of the urine filter column 7, then separate the urine filter column 7 from the lower through pipe 5, and use the upper sealing cap 13 to seal the upper through hole of the urine filter column 7. The urine filter column 7 containing urine exfoliated cells can be stored and transported at room temperature for a long time, waiting for subsequent detection.
综上所述,该用于核酸检测的尿液样本采集与处理装置,具有结构紧凑、省时省力和样本提取便捷的特点。解决了尿液样本核酸进行长时间保存和运输的问题。确保尿液样本进行核酸检测的准确性。In summary, the urine sample collection and processing device for nucleic acid testing has the characteristics of compact structure, time-saving and labor-saving, and convenient sample extraction. It solves the problem of long-term storage and transportation of urine sample nucleic acid and ensures the accuracy of nucleic acid testing of urine samples.
对于本领域技术人员而言,显然本实用新型不限于上述示范实施例的细节,而且在不背离实用新型的基本特征的情况下,能够以其他的具体形式实现本实用新型。因此无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本实用新型的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本实用新型内。不应将权利要求中的任何附图标记视为限制所涉及的权利要求。It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the basic features of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention. Any reference numerals in the claims should not be regarded as limiting the claims involved.
总之,以上所述仅为本实用新型的具体实施例,但本实用新型的结构特征并不局限于此,任何本领域的技术人员在本实用新型的领域内,所作的变化或修饰皆涵盖在本实用新型的专利范围之中。In summary, the above description is only a specific embodiment of the present invention, but the structural features of the present invention are not limited thereto. Any changes or modifications made by any technician in the field of the present invention are included in the patent scope of the present invention.
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