CN109804262B - 用于对对象进行成像的磁共振成像系统及其操作方法 - Google Patents

用于对对象进行成像的磁共振成像系统及其操作方法 Download PDF

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CN109804262B
CN109804262B CN201780062008.2A CN201780062008A CN109804262B CN 109804262 B CN109804262 B CN 109804262B CN 201780062008 A CN201780062008 A CN 201780062008A CN 109804262 B CN109804262 B CN 109804262B
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magnetic resonance
pulse sequence
sequence commands
fingerprint
control
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CN109804262A (zh
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K·佐默
M·G·赫勒
T·E·阿姆托尔
P·博尔纳特
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Koninklijke Philips NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56366—Perfusion imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/0263—Measuring blood flow using NMR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G01R33/4838—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective suppression or saturation of MR signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5608—Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/5635—Angiography, e.g. contrast-enhanced angiography [CE-MRA] or time-of-flight angiography [TOF-MRA]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4818—MR characterised by data acquisition along a specific k-space trajectory or by the temporal order of k-space coverage, e.g. centric or segmented coverage of k-space
    • G01R33/4824—MR characterised by data acquisition along a specific k-space trajectory or by the temporal order of k-space coverage, e.g. centric or segmented coverage of k-space using a non-Cartesian trajectory
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5607—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reducing the NMR signal of a particular spin species, e.g. of a chemical species for fat suppression, or of a moving spin species for black-blood imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
    • G01R33/5616—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE] using gradient refocusing, e.g. EPI
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10088—Magnetic resonance imaging [MRI]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing

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  • Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Magnetic Resonance Imaging Apparatus (AREA)
CN201780062008.2A 2016-10-07 2017-10-09 用于对对象进行成像的磁共振成像系统及其操作方法 Active CN109804262B (zh)

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EP16192733 2016-10-07
EP16192733.0 2016-10-07
PCT/EP2017/075614 WO2018065618A1 (en) 2016-10-07 2017-10-09 Combined arterial spin labeling and magnetic resonance fingerprinting

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CN109804262B true CN109804262B (zh) 2022-04-29

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EP (1) EP3523669B1 (enExample)
JP (1) JP7059263B6 (enExample)
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WO (1) WO2018065618A1 (enExample)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
US10143389B2 (en) 2014-04-22 2018-12-04 Case Western Reserve University Distinguishing diseased tissue from healthy tissue based on tissue component fractions using magnetic resonance fingerprinting (MRF)
US11747421B2 (en) * 2018-05-18 2023-09-05 Case Western Reserve University System and method for quantifying perfusion using a dictionary matching
EP3882850A1 (en) * 2020-03-20 2021-09-22 Siemens Healthcare GmbH Method and system for measuring a maturation stage using mri
EP4127758A4 (en) * 2020-03-28 2024-04-17 Özarslan, Evren MAGNETIC RESONANCE METHOD, SOFTWARE PRODUCT AND SYSTEM FOR DETERMINING A DIFFUSION PROPAGATOR OR RELATED DIFFUSION PARAMETERS FOR SPIN-LABELLED PARTICLES
EP3910358A1 (en) * 2020-05-15 2021-11-17 Koninklijke Philips N.V. Automated adjustment of the undersampling factor
US12681117B2 (en) * 2021-04-30 2026-07-14 Case Western Reserve University Systems and methods for integrated magnetic resonance imaging and magnetic resonance fingerprinting radiomics analysis
US20230368393A1 (en) * 2022-05-10 2023-11-16 Case Western Reserve University System and method for improving annotation accuracy in mri data using mr fingerprinting and deep learning
US12196831B2 (en) * 2022-11-18 2025-01-14 Regents Of The University Of Michigan Quantitative reduced field-of-view imaging system using 3D tailored inner volume excitation and pattern recognition

Citations (4)

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Publication number Priority date Publication date Assignee Title
US20030198940A1 (en) * 1999-10-05 2003-10-23 The Molecular Sciences Institute, Inc. Protein characterization system
CN1494871A (zh) * 2002-05-13 2004-05-12 ��ʽ���綫֥ 磁共振成像仪、流量量化仪及流量量化方法
CN103703383A (zh) * 2011-07-21 2014-04-02 皇家飞利浦有限公司 在mri装置中使用的位置标记
CN104780839A (zh) * 2012-09-19 2015-07-15 卡斯西部储备大学 核磁共振(nmr)指纹识别

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JP4574791B2 (ja) 1999-03-31 2010-11-04 株式会社東芝 Ｍｒｉ装置およびｍｒイメージング方法
US6717405B2 (en) * 2002-04-12 2004-04-06 Beth Israel Deaconess Medical Center, Inc. Arterial spin labeling using time varying gradients
US8965480B2 (en) 2010-04-14 2015-02-24 The Regents Of The University Of California Arterial blood flow and transit delay measurement using arterial spin labeling
US10627468B2 (en) 2011-03-18 2020-04-21 Case Western Reserve University Nuclear magnetic resonance (NMR) fingerprinting
US9097781B2 (en) 2012-04-12 2015-08-04 Mark Griswold Nuclear magnetic resonance (NMR) fingerprinting with parallel transmission
US10092199B2 (en) 2014-04-01 2018-10-09 Siemens Healthcare Gmbh MR imaging apparatus and method for generating a perfusion image with motion correction
US10143389B2 (en) * 2014-04-22 2018-12-04 Case Western Reserve University Distinguishing diseased tissue from healthy tissue based on tissue component fractions using magnetic resonance fingerprinting (MRF)
US10379189B2 (en) 2014-07-28 2019-08-13 Case Western Reserve University Simultaneous magnetic resonance angiography and perfusion with nuclear magnetic resonance fingerprinting

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030198940A1 (en) * 1999-10-05 2003-10-23 The Molecular Sciences Institute, Inc. Protein characterization system
CN1494871A (zh) * 2002-05-13 2004-05-12 ��ʽ���綫֥ 磁共振成像仪、流量量化仪及流量量化方法
CN103703383A (zh) * 2011-07-21 2014-04-02 皇家飞利浦有限公司 在mri装置中使用的位置标记
CN104780839A (zh) * 2012-09-19 2015-07-15 卡斯西部储备大学 核磁共振(nmr)指纹识别

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US20200050819A1 (en) 2020-02-13
WO2018065618A1 (en) 2018-04-12
JP7059263B2 (ja) 2022-04-25
US11226389B2 (en) 2022-01-18
JP7059263B6 (ja) 2022-06-03
EP3523669B1 (en) 2022-04-06
JP2019534748A (ja) 2019-12-05
CN109804262A (zh) 2019-05-24
EP3523669A1 (en) 2019-08-14

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