CN109770864B - Vascular endothelial function detection device, method and storage medium - Google Patents

Vascular endothelial function detection device, method and storage medium Download PDF

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Publication number
CN109770864B
CN109770864B CN201711114602.XA CN201711114602A CN109770864B CN 109770864 B CN109770864 B CN 109770864B CN 201711114602 A CN201711114602 A CN 201711114602A CN 109770864 B CN109770864 B CN 109770864B
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temperature
blood flow
module
blood
blocked
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CN109770864A (en
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方炎林
纳格哈维·迪沃雷·莫特扎
周伟
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Shenzhen Belter Health Measurement and Analysis Technology Co Ltd
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Shenzhen Belter Health Measurement and Analysis Technology Co Ltd
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Abstract

The invention is suitable for the technical field of vascular endothelial function detection, and provides a vascular endothelial function detection device, a method and a storage medium, wherein the method comprises the following steps: the pressurizing module pressurizes the blood vessel within a preset time to block blood flow; the temperature measuring module measures the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked; the processing module acquires the rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked, and acquires the cardiovascular event risk level corresponding to the rebound time according to the pre-established mapping relation between the rebound time and the cardiovascular event risk level; the display module displays the fingertip temperature measured by the temperature measurement module in real time in a graph mode, and displays the obtained cardiovascular event risk level. According to the invention, the cardiovascular event risk grade is obtained by testing the rebound time of the fingertip temperature, so that the problems of high detection cost and complex operation in the prior art are solved.

Description

Vascular endothelial function detection device, method and storage medium
Technical Field
The invention belongs to the technical field of physiological detection, and particularly relates to a vascular endothelial function detection device, a vascular endothelial function detection method and a storage medium.
Background
Vascular endothelial dysfunction has been considered by the medical community as a key factor in atherosclerosis for over a decade and is highly correlated with cardiovascular disease. Since endothelial dysfunction still has recoverability, the detection of endothelial function has become a major measure for the prevention of cardiovascular diseases in the medical community.
The current clinical method for detecting the vascular endothelial function mainly comprises the following steps: coronary angiography, brachial artery blood flow-mediated blood vessel diameter detection, peripheral artery tension index detection, endothelial activity factor detection and the like. However, the existing method for detecting the vascular endothelial function has high detection cost, complex operation and low detection efficiency due to expensive equipment.
Disclosure of Invention
In view of this, embodiments of the present invention provide a device, a method, and a storage medium for detecting a vascular endothelial function, so as to solve the problems of high detection cost and complex operation in the prior art.
A first aspect of an embodiment of the present invention provides a vascular endothelial function detection apparatus, including:
the device comprises a pressurizing module, a temperature measuring module, a display module and a processing module;
the processing module is respectively connected with the pressurizing module, the temperature measuring module and the display module;
the pressurizing module is used for pressurizing the blood vessel within a preset time to block blood flow;
the temperature measuring module is used for measuring the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked;
the processing module is used for acquiring the rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked, and acquiring the cardiovascular event risk level corresponding to the rebound time according to the pre-established mapping relation between the rebound time and the cardiovascular event risk level;
the display module is used for displaying the fingertip temperature measured by the temperature measurement module in real time in a graph mode and displaying the obtained cardiovascular event risk level;
wherein a short rebound time corresponds to a low risk rating for cardiovascular events.
A second aspect of the embodiments of the present invention provides a method for detecting vascular endothelial function, including:
applying pressure to the blood vessel for a predetermined time to block blood flow;
measuring the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked;
acquiring the rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked, and acquiring the cardiovascular event risk level corresponding to the rebound time according to the pre-established mapping relation between the rebound time and the cardiovascular event risk level;
displaying the fingertip temperature measured by the temperature measurement module in real time in a graph mode, and displaying the obtained cardiovascular event risk level;
wherein a short rebound time corresponds to a low risk rating for cardiovascular events.
A third aspect of embodiments of the present invention provides a computer-readable storage medium storing a computer program which, when executed by a processor, implements the steps of the method as provided in the first aspect above.
Compared with the prior art, the embodiment of the invention has the following beneficial effects: firstly, applying pressure to the blood vessel within a preset time to block blood flow; then measuring the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked; then, acquiring the rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked, and acquiring the cardiovascular event risk level corresponding to the rebound time according to the pre-established mapping relation between the rebound time and the cardiovascular event risk level; and finally, displaying the fingertip temperature measured by the temperature measuring module and the obtained cardiovascular event risk level in real time in a graph mode. The vascular endothelial function detection method detects the vascular endothelial function through the pre-established mapping relation between the fingertip temperature and the cardiovascular event, and can carry out daily continuous monitoring because the fingertip temperature is low in detection cost and easy to use. And the operation is simple and quick, and the practicability and the usability are strong.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise.
FIG. 1 is a block diagram of a device for detecting endothelial function of blood vessels according to an embodiment of the present invention;
FIG. 2 is a schematic flow chart of a method for detecting vascular endothelial function according to an embodiment of the present invention;
fig. 3 is a graph showing the variation of fingertip temperature according to the embodiment of the present invention.
Detailed Description
In the following description, for purposes of explanation and not limitation, specific details are set forth, such as particular system structures, techniques, etc. in order to provide a thorough understanding of the embodiments of the invention. It will be apparent, however, to one skilled in the art that the present invention may be practiced in other embodiments that depart from these specific details. In other instances, detailed descriptions of well-known systems, devices, circuits, and methods are omitted so as not to obscure the description of the present invention with unnecessary detail.
In order to explain the technical solution of the present invention, the following description will be given by way of specific examples.
Example one
Fig. 1 shows a block diagram of a vascular endothelial function detection apparatus provided in an embodiment of the present invention, and for convenience of description, only the parts related to the embodiment of the present invention are shown.
The vascular endothelial function test apparatus 1 includes: a pressurizing module 11, a temperature measuring module 12, a processing module 13 and a display module 14.
The pressurizing module 11 is used for pressurizing the blood vessel within a preset time to block blood flow;
the temperature measuring module 12 is used for measuring the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked;
the processing module 13 is configured to obtain a rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked, and obtain a cardiovascular event risk level corresponding to the rebound time according to a mapping relationship between the rebound time and the cardiovascular event risk level, which is established in advance;
a display module 14 for displaying the fingertip temperature measured by the temperature measurement module in real time in a graph manner and displaying the obtained cardiovascular event risk level.
Further, the pressurizing module 11 is specifically configured to inflate the blood pressure cuff after the vascular endothelial function detecting device is started by a preset key, stop inflating when the blood pressure parameter board monitors that the current blood pressure reaches a preset blood pressure value, and maintain the air pressure of the blood pressure cuff within the preset time to block blood flow.
Alternatively, the pressurizing module 11 includes:
the blood pressure cuff is used for pressurizing the blood vessel within the preset time;
and the blood pressure parameter board is used for monitoring the blood pressure in real time.
Optionally, the temperature measuring module 12 includes:
the first temperature sensor is used for measuring the fingertip temperature of the pressurizing module when the pressurizing module blocks blood flow in real time;
the second temperature sensor is used for measuring the fingertip temperature in real time when the blood flow is not blocked by the pressurizing module;
and the third temperature sensor is used for measuring the current ambient temperature in real time.
Optionally, the vascular endothelial function test apparatus 1 further includes:
the expansion module is used for measuring at least one of blood sugar, uric acid, cholesterol, high-density lipoprotein, low-density lipoprotein and triglyceride of a tester.
Optionally, the vascular endothelial function test apparatus 1 further includes:
and the temperature board is used for displaying the fingertip temperature measured by the temperature measuring module 12 when the pressurizing module blocks the blood flow, the fingertip temperature when the pressurizing module does not block the blood flow and the current environment temperature in real time.
Optionally, the vascular endothelial function test apparatus 1 further includes:
and the key module is used for controlling the switch of the vascular endothelial function detection device 1 and operating the pressurizing module 11, the temperature measuring module 12, the processing module 13 and the display module 14.
Example two
Fig. 2 shows an implementation process of a method for detecting vascular endothelial function according to an embodiment of the present invention, which is detailed as follows:
in step S201, a blood vessel is pressurized for a preset time to block blood flow.
In the embodiment of the present invention, optionally, after the vascular endothelial function detection device is activated by the preset button, the blood pressure cuff is inflated, and at the same time, the inflation is stopped when the blood pressure parameter board monitors that the current blood pressure reaches the preset blood pressure value, and the air pressure of the blood pressure cuff is maintained within the preset time to block the blood flow. The blood pressure parameter board monitors the current blood pressure by pressurizing the cuff to block the blood flow of brachial artery, then slowly reducing the pressure, wherein the arm can transmit sound and pressure small pulse during the process, the small pulse transmitted from the arm to the cuff is identified and differentiated, and the blood pressure value is obtained.
Optionally, when the air pressure of the blood pressure cuff is maintained within a preset time to block blood flow, the cuff pressure may be automatically adjusted according to the blood pressure monitored by the blood pressure parameter board, and the systolic pressure of the blood pressure cuff is maintained at a pressure of 35mmhg, so that the blood vessel endothelium function detection device is also suitable for people who cannot tolerate pressure, and complications caused by long-time blood flow blocking are reduced.
Step S202 measures the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked.
In the embodiment of the present invention, the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked are measured by a device having a temperature measurement function in the blood vessel function detection device, wherein the device having a temperature measurement function may be a temperature sensor, and the tester measures the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked by contacting the temperature sensor with the fingertip.
Optionally, the current ambient temperature is measured while measuring the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked, because the lower the ambient temperature is, the greater the heat loss of the fingertip is, so that the temperature rise value is smaller, and the test result is inaccurate, and the ambient temperature is measured to correct the influence of the ambient temperature on the measurement result.
Step S203, obtaining the rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked, and obtaining the cardiovascular event risk level corresponding to the rebound time according to the pre-established mapping relation between the rebound time and the cardiovascular event risk level.
Alternatively, the blood pressure cuff is deflated after a preset time period to allow blood to flow again while maintaining the pressure in the blood pressure cuff for a preset time period to block blood flow, the fingertip temperature is lowered due to lack of warm circulating blood, and blood flow is rapidly flushed into the forearm and fingers to cause a rise in fingertip temperature, which is positively correlated with cardiovascular reactivity. Specifically, in the process of deflating the blood pressure cuff after the preset time to circulate blood again, the shorter the time taken for the fingertip temperature to rise back to the fingertip temperature without blood flow blockage, the better the cardiovascular reactivity, and the longer the time taken for the fingertip temperature to rise back to the fingertip temperature without blood flow blockage, the worse the cardiovascular reactivity.
Optionally, the pre-established mapping relationship between the rebound time and the risk level of the cardiovascular event is a research result of the finger temperature change and the vascular function in the existing cardiovascular response test, the finger temperature change and the vascular function are linked through data obtained by clinical tests, and the shorter the rebound time is, the better the cardiovascular activity is, so that the risk level of the cardiovascular event is lower.
Step S204, displaying the fingertip temperature measured by the temperature measuring module in real time in a graph mode, and displaying the obtained cardiovascular event risk level.
Optionally, in the operation process of the blood vessel function detecting device, the display screen displays the change of the fingertip temperature in real time, wherein the change of the fingertip temperature is represented by a curve in a rectangular coordinate system, as shown in fig. 3, a horizontal axis represents time, and a vertical axis represents the fingertip temperature. Specifically, in the above-described graph, the time points of inflation and deflation of the blood pressure cuff are indicated by solid points, the fingertip temperature at the time when the blood flow is not blocked is set before the time point of inflation of the blood pressure cuff, the fingertip temperature at the time when the blood flow is blocked is set between the time point of inflation of the blood pressure cuff and the time point of deflation of the blood pressure cuff, and the change in the fingertip temperature at the time when the blood flow rises is set after the time point of deflation of the blood pressure cuff.
Therefore, the invention maintains the air pressure of the blood pressure cuff to block the blood flow within the preset time, the temperature of the fingertip is reduced due to lack of warm circulating blood, the blood pressure cuff is deflated after the preset time so as to circulate the blood again, the blood flow rapidly rushes into the forearm and the finger to cause the temperature of the fingertip to rise, the rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked is obtained, and the cardiovascular event risk grade corresponding to the rebound time is obtained according to the pre-established mapping relation between the rebound time and the cardiovascular event risk grade. The vascular endothelial function detection method detects the vascular endothelial function through the pre-established mapping relation between the fingertip temperature and the cardiovascular event, so that a user can know the risk of cardiovascular diseases according to the fingertip temperature.
It should be understood that, the sequence numbers of the steps in the foregoing embodiments do not imply an execution sequence, and the execution sequence of each process should be determined by its function and inherent logic, and should not constitute any limitation to the implementation process of the embodiments of the present invention.
It will be apparent to those skilled in the art that, for convenience and brevity of description, only the above-mentioned division of the functional units and modules is illustrated, and in practical applications, the above-mentioned function distribution may be performed by different functional units and modules according to needs, that is, the internal structure of the apparatus is divided into different functional units or modules to perform all or part of the above-mentioned functions. Each functional unit and module in the embodiments may be integrated in one processing unit, or each unit may exist alone physically, or two or more units are integrated in one unit, and the integrated unit may be implemented in a form of hardware, or in a form of software functional unit. In addition, specific names of the functional units and modules are only for convenience of distinguishing from each other, and are not used for limiting the protection scope of the present application. The specific working processes of the units and modules in the system may refer to the corresponding processes in the foregoing method embodiments, and are not described herein again.
In the above embodiments, the descriptions of the respective embodiments have respective emphasis, and reference may be made to the related descriptions of other embodiments for parts that are not described or illustrated in a certain embodiment.
Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the implementation. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present invention.
In the embodiments provided in the present invention, it should be understood that the disclosed apparatus/terminal device and method may be implemented in other ways. For example, the above-described embodiments of the apparatus/terminal device are merely illustrative, and for example, the division of the above modules or units is only one logical function division, and there may be other division manners in actual implementation, for example, a plurality of units or components may be combined or integrated into another system, or some features may be omitted, or not executed. In addition, the shown or discussed mutual coupling or direct coupling or communication connection may be an indirect coupling or communication connection through some interfaces, devices or units, and may be in an electrical, mechanical or other form.
The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of the embodiment.
In addition, functional units in the embodiments of the present invention may be integrated into one processing unit, or each unit may exist alone physically, or two or more units are integrated into one unit. The integrated unit can be realized in a form of hardware, and can also be realized in a form of a software functional unit.
The integrated modules/units described above, if implemented in the form of software functional units and sold or used as separate products, may be stored in a computer readable storage medium. Based on such understanding, all or part of the flow of the method according to the embodiments of the present invention may also be implemented by a computer program, which may be stored in a computer-readable storage medium and can implement the steps of the embodiments of the method when the computer program is executed by a processor. . The computer program includes computer program code, and the computer program code may be in a source code form, an object code form, an executable file or some intermediate form. The computer readable medium may include: any entity or device capable of carrying the above-mentioned computer program code, recording medium, usb disk, removable hard disk, magnetic disk, optical disk, computer Memory, Read-Only Memory (ROM), Random Access Memory (RAM), electrical carrier wave signal, telecommunication signal, software distribution medium, etc. It should be noted that the computer readable medium described above may be suitably increased or decreased as required by legislation and patent practice in jurisdictions, for example, in some jurisdictions, computer readable media excludes electrical carrier signals and telecommunications signals in accordance with legislation and patent practice.
The above embodiments are only used for illustrating the technical solutions of the present invention, and not for limiting the same; although the present invention has been described in detail with reference to the above embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the above embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not substantially depart from the spirit and scope of the embodiments of the present invention, and are intended to be included within the scope of the present invention.

Claims (10)

1. A vascular endothelial function test device, comprising:
the device comprises a pressurizing module, a temperature measuring module, a display module and a processing module;
the processing module is respectively connected with the pressurizing module, the temperature measuring module and the display module;
the pressurizing module is used for pressurizing the blood vessel within a preset time to block blood flow;
the temperature measuring module is used for measuring the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked;
the processing module is used for acquiring the rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked, and acquiring the cardiovascular event risk level corresponding to the rebound time according to the pre-established mapping relation between the rebound time and the cardiovascular event risk level;
the display module is used for displaying the fingertip temperature measured by the temperature measurement module in real time in a graph mode and displaying the obtained cardiovascular event risk level;
wherein a short rebound time corresponds to a low risk rating for cardiovascular events.
2. The vascular endothelial function testing device of claim 1, wherein the pressurizing module comprises:
the blood pressure cuff is used for pressurizing the blood vessel within the preset time;
and the blood pressure parameter board is used for monitoring the blood pressure in real time.
3. The vascular endothelial function testing device of claim 2, wherein the pressurizing module,
the blood pressure parameter board is specifically used for inflating the blood pressure cuff after the blood vessel endothelium function detection device is started through a preset key, stopping inflating when the blood pressure parameter board monitors that the current blood pressure reaches a preset blood pressure value, and maintaining the air pressure of the blood pressure cuff within the preset time to block blood flow.
4. The vascular endothelial function test device of claim 1, wherein the temperature measurement module comprises:
the first temperature sensor is used for measuring the fingertip temperature of the pressurizing module when the pressurizing module blocks blood flow in real time;
the second temperature sensor is used for measuring the fingertip temperature in real time when the blood flow is not blocked by the pressurizing module;
and the third temperature sensor is used for measuring the current ambient temperature in real time.
5. The vascular endothelial function test device of any one of claims 1 to 4, further comprising:
the expansion module is connected with the processing module;
the expansion module is used for measuring at least one of blood sugar, uric acid, cholesterol, high-density lipoprotein, low-density lipoprotein and triglyceride of a tester.
6. A method for detecting vascular endothelial function, comprising:
applying pressure to the blood vessel for a predetermined time to block blood flow;
measuring the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked;
acquiring the rebound time from the fingertip temperature when the blood flow is blocked to the fingertip temperature when the blood flow is not blocked, and acquiring the cardiovascular event risk level corresponding to the rebound time according to the pre-established mapping relation between the rebound time and the cardiovascular event risk level;
displaying the fingertip temperature measured by the temperature measurement module in real time in a graph mode, and displaying the obtained cardiovascular event risk level;
wherein a short rebound time corresponds to a low risk rating for cardiovascular events.
7. The method for detecting endothelial function of blood vessels according to claim 6, wherein the applying pressure to the blood vessels for the predetermined time to block the blood flow comprises:
and after the vascular endothelial function detection device is started through a preset key, inflating the blood pressure cuff, stopping inflating when the blood pressure parameter board monitors that the current blood pressure reaches a preset blood pressure value, and maintaining the air pressure of the blood pressure cuff within the preset time to block blood flow.
8. The method for detecting vascular endothelial function according to claim 6, wherein the measuring the fingertip temperature when the blood flow is blocked and the fingertip temperature when the blood flow is not blocked further comprises:
measuring the fingertip temperature of the pressurizing module when the pressurizing module blocks blood flow in real time;
measuring the fingertip temperature in real time when the blood flow is not blocked by the pressurizing module;
the current ambient temperature is measured in real time.
9. The method of any one of claims 6-8, further comprising:
at least one of blood glucose, uric acid, cholesterol, high density lipoprotein, low density lipoprotein, and triglyceride is measured.
10. A computer-readable storage medium, in which a computer program is stored, which, when being executed by a processor, carries out the steps of the method for detecting vascular endothelial function according to any one of claims 6 to 9.
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