CN109731071A - A kind of skin barrier reparation weak acid dipping cream - Google Patents

A kind of skin barrier reparation weak acid dipping cream Download PDF

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Publication number
CN109731071A
CN109731071A CN201910189498.3A CN201910189498A CN109731071A CN 109731071 A CN109731071 A CN 109731071A CN 201910189498 A CN201910189498 A CN 201910189498A CN 109731071 A CN109731071 A CN 109731071A
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parts
radix
cream
skin
weak acid
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CN201910189498.3A
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何勇
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Guizhou Longyutang Pharmaceutical Co Ltd
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Guizhou Longyutang Pharmaceutical Co Ltd
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Abstract

The invention discloses a kind of skin barriers to repair weak acid dipping cream, it is raw material that the dipping cream, which is by the Chinese medicine of following parts by weight: 10-30 parts of eclipta, 20-40 parts of kuh-seng, 10-30 parts of the fruit of summer cypress, 10-30 parts of cortex moutan, 10-30 parts of smilax, 20-45 parts of Herba Epimedii, 10-30 parts of Chinese scholartree branch, 10-30 parts of wrinkled giant hyssop, 10-30 parts of lavender, 10-30 parts of ginseng, 10-30 parts of asparagus fern, Radix Ophiopogonis 10-30 part, 10-30 parts of radix polygonati officinalis, 10-30 parts of Semen sesami nigrum, 10-30 parts of Lysimachia foenum-graecum, 10-30 parts of Common St.Paulswort Herb, 20-40 parts of cortex dictamni, 10-30 parts of Cortex Phellodendri, 10-30 parts of Radix Angelicae Sinensis, 10-30 parts of Radix Isatidis, it is 5-15 parts windproof, 5-15 parts of mulberry leaf, 10-30 parts of peppermint, it is profound 10-30 parts, 5-15 parts of polygonum perfoliatum of ginseng;With expelling wind and clearing away heat eliminating dampness, the desinsection that detoxifies treats tinea, the health-care efficacy of moisturizing inflammation-resisting itch-stopping.

Description

A kind of skin barrier reparation weak acid dipping cream
Technical field
The present invention relates to a kind of Chinese medicine shower lotion, it is prepared more particularly to a kind of extracted as raw material using Chinese medicine Skin barrier repairs weak acid dipping cream.
Background technique
Skin is the maximum organ of human body, has the barrier protection effect of defence exopathogen invasion outer, also has secretion, inhales The multiple functions such as receipts, infiltration, excretion, feeling.Skin area is very big, and there are many pore, is that drug absorption enters human body performance pharmacology One of important channel of drug action.
Acute and chronic skin disease is clinically often to give disease person life and work belt with the common diseases in people's life Carry out larger puzzlement, but since the skin disease cause of disease is complex, body pathology variation is varied, therefore merely using for oral use Medicine treat dermatopathy, no matter Chinese medicine or doctor trained in Western medicine medication, exist centainly limit to, so that skin disease is shown as easy to recur, difficult root The characteristics of controlling.Acute and chronic skin disease is clinically often to live and work to disease person with the common diseases in people's life Larger puzzlement is brought, but since the skin disease cause of disease is complex, body pathology variation is varied, therefore simple using oral Medication treat dermatopathy, no matter Chinese medicine or doctor trained in Western medicine medication, exist centainly limit to, show as skin disease easy to recur, difficult The characteristics of radical cure.
Chinese medicine prepares bubble bath preparations using Chinese medicine, takes full advantage of the physiological property of skin " infiltration absorbs, excretion ", both Drug can be made directly to play drug action in the diseased region of dermatopathy, more quickly improve dermatopathy symptom, alleviate and suffer from Person's pain;Percutaneous can absorb again makes drug by blood vessels, channels and collaterals thoroughly up to internal organs, and decrease, which even is eliminated, leads to skin The cause of disease of illness morbidity.Therefore, for the treatment of dermatopathy or health care, Traditional Chinese medicine medicated bath therapy be can yet be regarded as, and " sample is simultaneous for one kind Control " good method.
Therefore, my company is on developing health treatment dosage form selection effective for acute and chronic skin disease, it is determined that Chinese medicine The direction of dipping.In development process, it has been found that due to human skin surface retain urea, uric acid, salinity, lactic acid, The acidic materials such as amino acid, free fatty acid, so skin surface often shows faintly acid.Normal skin surface pH value is about 5.0~ 6.5, average value 5.8.Human skin is only in normal pH value range, that is, is in faintly acid, and can just resist the external world has Evil, stimulant, daylight enter, while having the function of moisturizing and adjusting anti-inflammatory.On the contrary, when alkalinity is presented in skin surface for a long time When (pH value is greater than 7.0), the alkali neutralization ability of skin will weaken, so that skin self-defense scarce capacity, skin are easily quick Impression damage, bacterium easy to breed cause infection inflammation and cause physical skin barrier impaired.Skin barrier is impaired directly to cause urgency Chronic dermatosis, such as dry skin, skin aging, pigmentation atopic dermatitis, eczema, psoriasis, ichthyosis, solar lentigines skin The skin greasings such as the skin sensitivities such as inflammation, irritant dermatitis, steroid dependent dermatitis, seborrhea disease, such as acne, vinasse The skin diseases such as nose, seborrhea.New product " Mu Shengshu-skin barrier repairs weak acid dipping cream " organic knot of my company's research and development It closes " Traditional Chinese medicine medicated bath " " skin faintly acid feature ", manufactured dipping product pH value 5.0~6.5 is weakly acidic, to skin surface Acid, alkali have certain buffer capacity (that is, neutralization energy of skin), can not only safeguard skin surface weak acid environment, but also can pass through Drug effect QI invigorating Wen Yanggu table and enhance skin barrier.It was verified that this product property is mild, wide indications, effect directly, It has no toxic side effect.
Summary of the invention
In view of the deficiencies of the prior art, it is an object of the present invention to provide a kind of skin barriers to repair weak acid dipping cream.
What the purpose of the present invention was realized by the following technical solutions: a kind of skin barrier reparation weak acid dipping cream, it It is prepared by the following method to obtain:
(1) weigh the Chinese medicine material of following parts by weight: 10-30 parts of eclipta, 20-40 parts of kuh-seng, 10-30 parts of the fruit of summer cypress, 10-30 parts of cortex moutan, 10-30 parts of smilax, 20-45 parts of Herba Epimedii, Chinese scholartree branch 10-30 parts, 10-30 parts of wrinkled giant hyssop, lavender 10-30 Part, 10-30 parts of ginseng, 10-30 parts of asparagus fern, Radix Ophiopogonis 10-30 part, 10-30 parts of radix polygonati officinalis, 10-30 parts of Semen sesami nigrum, Lysimachia foenum-graecum 10-30 10-30 parts of Fen, Common St.Paulswort Herb, 20-40 parts of cortex dictamni, 10-30 parts of Cortex Phellodendri, 10-30 parts of Radix Angelicae Sinensis, 10-30 parts of Radix Isatidis, radix saposhnikoviae 5-15 Part, 5-15 parts of mulberry leaf, 10-30 parts of peppermint, 10-30 parts of radix scrophulariae, 5-15 parts of polygonum perfoliatum;
(2) water extracts: the weighed Chinese medicine material of step 1 being rinsed with water, is sliced, is placed in extractor and adds water to cook 2 times, press Chinese medicine material gross mass meter, for the first time plus 8 times of water amounts, immersion 0.5 hour decoct 0.5 hour;Second plus 6 times of water amounts, decoct 1 hour, collecting decoction, filtering, it was at 70 DEG C that filtrate decompression, which is concentrated into relative density,Clear cream when, stop concentration, Receive cream;It is sealed;
(3) auxiliary material of following parts by weight: 5-15 parts of glycerol, 2-5 parts of sodium chloride, 5-15 parts of alkyl glycosides, isothiazole is weighed 0.5-2 parts of quinoline ketone non-oxidative antimicrobial, 30-50 parts of sodium lauroyl sarcosine, fatty amide propyl dimethyl betaine 30-50 Part, 0.5-2 parts of guar gum, 0.2-0.3 parts of disodium ethylene diamine tetraacetate, 70-80 parts of cocoanut fatty acid diethanolamide;
(4) auxiliary material of following parts by weight: 40-60 parts of ethoxylated alkyl sulfate, citric acid 1-3 is successively weighed Part, 3-5 parts of essence;
(5) it prepares lotion: clear cream prepared by above-mentioned steps 2 being placed in ingredient heating tank, when being heated to 80 DEG C, successively The weighed auxiliary material of above-mentioned steps 3 is added, stirring stops heating to after being completely dissolved.When temperature drop to it is low enter 30 DEG C when, be added The weighed auxiliary material of above-mentioned steps 4 is stirred to being completely dissolved, and is obtained skin barrier and is repaired weak acid dipping cream.
Further, the Chinese medicine material is preferred are as follows: 20 parts of eclipta, 30 parts of kuh-seng, 20 parts of the fruit of summer cypress, cortex moutan 20 Part, 20 parts of smilax, 30 parts of Herba Epimedii, Chinese scholartree branch 20 parts, 20 parts of wrinkled giant hyssop, 20 parts of lavender, 20 parts of ginseng, 20 parts of asparagus fern, Radix Ophiopogonis 20 parts, 20 parts of radix polygonati officinalis, 20 parts of Semen sesami nigrum, 20 20 parts of Fen, Common St.Paulswort Herb of Lysimachia foenum-graecum, 30 parts of cortex dictamni, 20 parts of Cortex Phellodendri, 20 parts of Radix Angelicae Sinensis, 20 parts of Radix Isatidis, windproof 10 parts, 10 parts of mulberry leaf, 20 parts of peppermint, 20 parts of radix scrophulariae, 10 parts of polygonum perfoliatum.
Further, the auxiliary material is preferred are as follows: 10 parts of glycerol, 3 parts of sodium chloride, 10 parts of alkyl glycosides, isothiazolinone 1 part of non-oxidative antimicrobial, 40 parts of sodium lauroyl sarcosine, 40 parts of fatty amide propyl dimethyl betaine, 1 part of guar gum, second 0.25 part of edetate disodium, 75 parts of cocoanut fatty acid diethanolamide, 50 parts of ethoxylated alkyl sulfate, citric acid 2 parts, 4 parts of essence.Beneficial effects of the present invention are as follows:
The invention has the advantages that skin barrier reparation weak acid dipping cream pH value prepared by the present invention is weakly acidic, tool There is expelling wind and clearing away heat eliminating dampness, removing toxic substances desinsection treats tinea, safeguards skin surface weak acid environment, moisturizing inflammation-resisting itch-stopping, and table is consolidated in tonifying Qi Yiyang, Clean the health-care efficacy of moist skin.Rehabilitation and daily skin care suitable for acute and chronic dermatopathy.
Specific embodiment
Below according to preferred embodiment the present invention is described in detail, the objects and effects of the present invention be will become more apparent, with Under in conjunction with the embodiments, the present invention will be described in further detail.It should be appreciated that specific embodiment described herein is only used To explain the present invention, it is not intended to limit the present invention.
Embodiment 1
Eclipta 25g, kuh-seng 20g, fruit of summer cypress 25g, cortex moutan 25g, smilax 25g, Herba Epimedii 35g, Chinese scholartree branch are taken respectively 25g, wrinkled giant hyssop 25g, lavender 25g, ginseng 25g, asparagus fern 25g, Radix Ophiopogonis 25g, radix polygonati officinalis 25g, Semen sesami nigrum 25g, Lysimachia foenum-graecum 25g, pig Xian grass 25g, cortex dictamni 25g, Cortex Phellodendri 25g, Radix Angelicae Sinensis 25g, Radix Isatidis 25g, radix saposhnikoviae 15g, mulberry leaf 15g, peppermint 30g, radix scrophulariae 15g, Polygonum perfoliatum 15g, is got express developed with Drinking Water, and rhizome, branch class medicinal material are sliced, extractor is placed in and adds water to cook 2 times, and first Secondary plus 8 times of amounts of water impregnate half an hour, decoct 0.5 hour, and for the second time plus 6 times of amounts of water decoct 1 hour, collecting decoction, filtration, filtrate When being concentrated under reduced pressure into the clear cream that relative density is 1.0~1.20 (70 DEG C), stop concentration, receives cream.The another device of clear cream is sealed.It is standby With.
Above-mentioned spare clear cream is placed in ingredient heating tank, when being heated to 80 DEG C, sequentially adds auxiliary material: glycerol 5g, Sodium chloride 5g, alkyl glycosides 5g, isothiazolinone non-oxidative antimicrobial 2g, sodium lauroyl sarcosine 30g, fatty amide propyl two Methyl betaine 30g, guar gum 2g, disodium ethylene diamine tetraacetate 0.2g, cocoanut fatty acid diethanolamide 80g, stirring 35 Minute to after being completely dissolved, stops heating.When temperature drop to it is low enter 30 DEG C when, be added auxiliary material: ethoxylated alkyl sulfate 15g, citric acid 3g, daily essence 3ml, stirring to be completely dissolved lotion.It is sealed after lotion room temperature, it is spare.
Above-mentioned emulsion is pressed into defined specification after the assay was approved and carries out filling, bottling, that is, it is weak that skin barrier reparation is made Sour dipping cream.
Embodiment 2
Eclipta 10g, kuh-seng 40g, fruit of summer cypress 10g, cortex moutan 30g, smilax 10g, Herba Epimedii 45g, Chinese scholartree branch are taken respectively 10g, wrinkled giant hyssop 30g, lavender 10g, ginseng 10g, asparagus fern 30g, Radix Ophiopogonis 10g, radix polygonati officinalis 30g, Semen sesami nigrum 10g, Lysimachia foenum-graecum 30g, pig Xian grass 10g, cortex dictamni 40g, Cortex Phellodendri 10g, Radix Angelicae Sinensis 30g, Radix Isatidis 10g, radix saposhnikoviae 15g, mulberry leaf 5g, peppermint 20g, radix scrophulariae 10g, thick stick Plate returns 15g, is got express developed with Drinking Water, and rhizome, branch class medicinal material are sliced, extractor is placed in and adds water to cook 2 times, for the first time Add 8 times of amounts of water to impregnate half an hour, decoct 0.5 hour, for the second time plus 6 times of amounts of water decoct 1 hour, collecting decoction, and filtration, filtrate subtracts When pressure is concentrated into the clear cream that relative density is 1.0~1.20 (70 DEG C), stop concentration, receives cream.The another device of clear cream is sealed.It is standby With.
Above-mentioned spare clear cream is placed in ingredient heating tank, when being heated to 80 DEG C, sequentially adds auxiliary material: glycerol 5g, Sodium chloride 5g, alkyl glycosides 5g, isothiazolinone non-oxidative antimicrobial 2g, sodium lauroyl sarcosine 30g, fatty amide propyl two Methyl betaine 30g, guar gum 2g, disodium ethylene diamine tetraacetate 0.2g, cocoanut fatty acid diethanolamide 80g, stirring 35 Minute to after being completely dissolved, stops heating.When temperature drop to it is low enter 30 DEG C when, be added auxiliary material: ethoxylated alkyl sulfate 15g, citric acid 3g, daily essence 3ml, stirring to be completely dissolved lotion.It is sealed after lotion room temperature, it is spare.
Above-mentioned emulsion is pressed into defined specification after the assay was approved and carries out filling, bottling, that is, it is weak that skin barrier reparation is made Sour dipping cream.
Embodiment 3
Eclipta 30g, kuh-seng 30g, fruit of summer cypress 30g, cortex moutan 10g, smilax 30g, Herba Epimedii 20g, Chinese scholartree branch are taken respectively 30g, wrinkled giant hyssop 10g, lavender 30g, ginseng 30g, asparagus fern 10g, Radix Ophiopogonis 30g, radix polygonati officinalis 10g, Semen sesami nigrum 30g, Lysimachia foenum-graecum 10g, pig Xian grass 30g, cortex dictamni 20g, Cortex Phellodendri 30g, Radix Angelicae Sinensis 10g, Radix Isatidis 30g, radix saposhnikoviae 5g, mulberry leaf 15g, peppermint 30g, radix scrophulariae 20g, thick stick Plate returns 5g, is got express developed with Drinking Water, and rhizome, branch class medicinal material are sliced, extractor is placed in and adds water to cook 2 times, for the first time Add 8 times of amounts of water to impregnate half an hour, decoct 0.5 hour, for the second time plus 6 times of amounts of water decoct 1 hour, collecting decoction, and filtration, filtrate subtracts When pressure is concentrated into the clear cream that relative density is 1.0~1.20 (70 DEG C), stop concentration, receives cream.The another device of clear cream is sealed.It is standby With.
Above-mentioned spare clear cream is placed in ingredient heating tank, when being heated to 80 DEG C, sequentially adds auxiliary material: glycerol 5g, Sodium chloride 5g, alkyl glycosides 5g, isothiazolinone non-oxidative antimicrobial 2g, sodium lauroyl sarcosine 30g, fatty amide propyl two Methyl betaine 30g, guar gum 2g, disodium ethylene diamine tetraacetate 0.2g, cocoanut fatty acid diethanolamide 80g, stirring 35 Minute to after being completely dissolved, stops heating.When temperature drop to it is low enter 30 DEG C when, be added auxiliary material: ethoxylated alkyl sulfate 15g, citric acid 3g, daily essence 3ml, stirring to be completely dissolved lotion.It is sealed after lotion room temperature, it is spare.
Above-mentioned emulsion is pressed into defined specification after the assay was approved and carries out filling, bottling, that is, it is weak that skin barrier reparation is made Sour dipping cream.
The verifying that weak acid dipping cream carries out test data is repaired to skin barrier made of embodiment 1-3 respectively.
The present invention has the function of that antibacterial, specific testing result are as follows:
1), the present invention in weak acid dipping cream 1:100 dilute solution to concentration 2.53*104The golden yellow grape of cfu/ml Coccus test bacteria suspension acts on 20min, each secondary bacteriostasis rate > 90%, and product has staphylococcus aureus stronger antibacterial Effect.
2), the dilute solution of weak acid dipping cream 1:100 of the present invention is to concentration 4.19*104The Candida albicans of cfu/ml tries It tests and acts on 20min, each secondary bacteriostasis rate > 90% with bacteria suspension, product has stronger bacteriostasis to Candida albicans.
3), weak acid dipping cream of the present invention is after 37 DEG C keep the temperature 90 days, and the dilute solution of 1:100 is to Staphylococcus aureus Bacterium, Candida albicans test act on 20min, each secondary bacteriostasis rate > 90% with bacteria suspension, and preceding fungistatic effect is not significant with storing Difference shows that product stablizes staphylococcus aureus, Candida albicans fungistatic effect.
The present invention has the function of that improvement pruitus, specific test result are as follows:
1) the medical cutaneous pruritus 65 Cases of Patients of Low Potassium of certain institute's Dermatology Outpatient Department, is chosen, is randomly divided into two groups, treatment group 35 Example, control group 30.Two groups of patients no significant difference (p > 0.5) in age, gender, the course of disease, is comparable.
2), curative effect determinate standard: recovery from illness: itch completely disappears, and secondary skin lesion disappears substantially;Effective: itch is substantially reduced, Excitation skin lesion is obviously improved;Effective: itch mitigates, and secondary skin lesion makes moderate progress;Invalid: itch is unchanged with associated disease.With Recovery from illness plus effective calculating are efficient.
3), result is as shown in table 1 below:
Table 1
Seen from table 1 above, skin barrier prepared by the present invention, which repairs weak acid dipping cream, has expelling wind and clearing away heat eliminating dampness, solution poisoning Worm treats tinea, safeguards skin surface weak acid environment, moisturizing inflammation-resisting itch-stopping, and table is consolidated in tonifying Qi Yiyang, cleans the health care function of moist skin Effect.
It will appreciated by the skilled person that being not used to limit the foregoing is merely the preferred embodiment of invention System invention, although invention is described in detail referring to previous examples, for those skilled in the art, still It can modify to the technical solution of aforementioned each case history or equivalent replacement of some of the technical features.It is all Within the spirit and principle of invention, modification, equivalent replacement for being made etc. be should be included within the protection scope of invention.

Claims (3)

1. a kind of skin barrier repairs weak acid dipping cream, which is characterized in that it is prepared by the following method to obtain:
(1) Chinese medicine material of following parts by weight: 10-30 parts of eclipta, 20-40 parts of kuh-seng, 10-30 parts of the fruit of summer cypress, tree peony is weighed 10-30 parts of skin, 10-30 parts of smilax, 20-45 parts of Herba Epimedii, Chinese scholartree branch 10-30 parts, 10-30 parts of wrinkled giant hyssop, 10-30 parts of lavender, 10-30 parts of ginseng, 10-30 parts of asparagus fern, Radix Ophiopogonis 10-30 part, 10-30 parts of radix polygonati officinalis, 10-30 parts of Semen sesami nigrum, 10-30 parts of Lysimachia foenum-graecum, 10-30 parts of Common St.Paulswort Herb, 20-40 parts of cortex dictamni, 10-30 parts of Cortex Phellodendri, 10-30 parts of Radix Angelicae Sinensis, 10-30 parts of Radix Isatidis, 5-15 parts of radix saposhnikoviae, 5-15 parts of mulberry leaf, 10-30 parts of peppermint, 10-30 parts of radix scrophulariae, 5-15 parts of polygonum perfoliatum.
(2) water extracts: the weighed Chinese medicine material of step 1 being rinsed with water, is sliced, is placed in extractor and adds water to cook 2 times, by Chinese medicine Total mass of raw material meter, for the first time plus then 8 times of water amounts, immersion about 0.5 hour decoct about 0.5 hour;Second plus 6 times of water amounts, It decocts about 1 hour, collecting decoction, filtering, it is at 70 DEG C that filtrate decompression, which is concentrated into relative density,Clear cream when, stop It is only concentrated, receives cream;It is sealed.
(3) auxiliary material of following parts by weight: 5-15 parts of glycerol, 2-5 parts of sodium chloride, 5-15 parts of alkyl glycosides, isothiazolinone is weighed 0.5-2 parts of non-oxidative antimicrobial, 30-50 parts of sodium lauroyl sarcosine, 30-50 parts of fatty amide propyl dimethyl betaine, melon That 0.5-2 parts of glue, 0.2-0.3 parts of disodium ethylene diamine tetraacetate, 70-80 parts of cocoanut fatty acid diethanolamide.
(4) auxiliary material of following parts by weight: 40-60 parts of ethoxylated alkyl sulfate, 1-3 parts of citric acid, perfume is successively weighed It is 3-5 parts smart.
(5) prepare lotion: clear cream prepared by above-mentioned steps 2 is placed in ingredient heating tank, when being heated to about 80 DEG C, successively plus Enter the weighed auxiliary material of above-mentioned steps 3, stirring stops heating to after being completely dissolved.When temperature is decreased below 30 DEG C, in addition The weighed auxiliary material of step 4 is stated, is stirred to being completely dissolved, skin barrier is obtained and repairs weak acid dipping cream.
2. skin barrier according to claim 1 repairs weak acid dipping cream, which is characterized in that the Chinese medicine material is preferred Are as follows: 20 parts of eclipta, 30 parts of kuh-seng, 20 parts of the fruit of summer cypress, 20 parts of cortex moutan, 20 parts of smilax, 30 parts of Herba Epimedii, Chinese scholartree branch 20 parts, 20 parts of wrinkled giant hyssop, 20 parts of lavender, 20 parts of ginseng, 20 parts of asparagus fern, 20 parts of Radix Ophiopogonis, 20 parts of radix polygonati officinalis, 20 parts of Semen sesami nigrum, Lysimachia foenum-graecum 20 20 parts of Fen, Common St.Paulswort Herb, 30 parts of cortex dictamni, 20 parts of Cortex Phellodendri, 20 parts of Radix Angelicae Sinensis, 20 parts of Radix Isatidis, windproof 10 parts, 10 parts of mulberry leaf, peppermint 20 parts, 20 parts of radix scrophulariae, 10 parts of polygonum perfoliatum.
3. skin barrier according to claim 1 repairs weak acid dipping cream, which is characterized in that the auxiliary material is preferred are as follows: 10 parts of glycerol, 3 parts of sodium chloride, 10 parts of alkyl glycosides, 1 part of isothiazolinone non-oxidative antimicrobial, 40 parts of sodium lauroyl sarcosine, 40 parts of fatty amide propyl dimethyl betaine, 1 part of guar gum, 0.25 part of disodium ethylene diamine tetraacetate, coco-nut oil fatty acid two 75 parts of glycollic amide, 50 parts of ethoxylated alkyl sulfate, 2 parts of citric acid, 4 parts of essence.
CN201910189498.3A 2019-03-13 2019-03-13 A kind of skin barrier reparation weak acid dipping cream Pending CN109731071A (en)

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Publication number Priority date Publication date Assignee Title
WO2021105339A1 (en) * 2019-11-28 2021-06-03 Ceva Sante Animale Shampoo veterinary compositions

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Publication number Priority date Publication date Assignee Title
CN1504205A (en) * 2002-11-28 2004-06-16 贵州丽康制药公司 Medicine for skin disease
CN105997678A (en) * 2016-06-22 2016-10-12 广州科玛生物科技股份有限公司 Washing and care two-in-one infant shower gel

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021105339A1 (en) * 2019-11-28 2021-06-03 Ceva Sante Animale Shampoo veterinary compositions
CN114980977A (en) * 2019-11-28 2022-08-30 法国诗华大药厂 Shampoo composition for animal

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