CN109689892A - 用于检测寻常型间质性肺炎的方法和系统 - Google Patents

用于检测寻常型间质性肺炎的方法和系统 Download PDF

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Publication number
CN109689892A
CN109689892A CN201780055050.1A CN201780055050A CN109689892A CN 109689892 A CN109689892 A CN 109689892A CN 201780055050 A CN201780055050 A CN 201780055050A CN 109689892 A CN109689892 A CN 109689892A
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G·C·肯尼迪
黄静
Y·崔
丹尼尔·潘克拉茨
帕特里克·肖恩·沃尔什
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Veracyte Inc
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Data Mining & Analysis (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Evolutionary Biology (AREA)
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  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
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  • Artificial Intelligence (AREA)
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  • Databases & Information Systems (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Pulmonology (AREA)
CN201780055050.1A 2016-09-07 2017-09-06 用于检测寻常型间质性肺炎的方法和系统 Pending CN109689892A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662384609P 2016-09-07 2016-09-07
US62/384,609 2016-09-07
US201762528899P 2017-07-05 2017-07-05
US62/528,899 2017-07-05
PCT/US2017/050358 WO2018048960A1 (en) 2016-09-07 2017-09-06 Methods and systems for detecting usual interstitial pneumonia

Publications (1)

Publication Number Publication Date
CN109689892A true CN109689892A (zh) 2019-04-26

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CN201780055050.1A Pending CN109689892A (zh) 2016-09-07 2017-09-06 用于检测寻常型间质性肺炎的方法和系统

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US (2) US20190330680A1 (enExample)
EP (2) EP4424840A1 (enExample)
JP (2) JP2019528697A (enExample)
CN (1) CN109689892A (enExample)
AU (1) AU2017324949B2 (enExample)
CA (1) CA3033241A1 (enExample)
WO (1) WO2018048960A1 (enExample)

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EP2360278A1 (en) 2005-04-14 2011-08-24 Trustees Of Boston University Diagnostic for lung disorders using class prediction
EP2605018A1 (en) 2006-03-09 2013-06-19 The Trustees of the Boston University Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
AU2008302076B2 (en) 2007-09-19 2015-06-11 The Trustees Of Boston University Identification of novel pathways for drug development for lung disease
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
EP3360978A3 (en) 2009-05-07 2018-09-26 Veracyte, Inc. Methods for diagnosis of thyroid conditions
EP2968988A4 (en) 2013-03-14 2016-11-16 Allegro Diagnostics Corp METHOD FOR EVALUATING A COPD STATUS
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
US20170335396A1 (en) 2014-11-05 2017-11-23 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
EP4180531A3 (en) 2016-05-12 2023-08-23 Trustees of Boston University Nasal epithelium gene expression signature and classifier for the prediction of lung cancer
US10927417B2 (en) 2016-07-08 2021-02-23 Trustees Of Boston University Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions
EP3886696A4 (en) * 2018-11-29 2022-08-24 SomaLogic Operating Co., Inc. PROCEDURE FOR DETERMINING DISEASE RISK USING A COMBINATION OF DOWNSAMPLING OF CLASS IMBALANCED DATASETS WITH SURVIVAL ANALYSIS
WO2020132520A2 (en) * 2018-12-20 2020-06-25 Veracyte, Inc. Methods and systems for detecting genetic fusions to identify a lung disorder
US11043304B2 (en) 2019-02-26 2021-06-22 Tempus Labs, Inc. Systems and methods for using sequencing data for pathogen detection
WO2021028726A2 (en) 2019-07-03 2021-02-18 Bostongene Corporation Systems and methods for sample preparation, sample sequencing, and sequencing data bias correction and quality control
WO2021077026A1 (en) * 2019-10-16 2021-04-22 Icahn School Of Medicine At Mount Sinai Systems and methods for detecting a disease condition
EP4150628A2 (en) * 2020-05-12 2023-03-22 Synaptic ApS An individualized group testing method for medical test samples
WO2022261437A2 (en) * 2021-06-11 2022-12-15 Acceleron Pharma Inc. Actrii proteins and uses thereof
WO2025117806A1 (en) * 2023-11-30 2025-06-05 Arizona Board Of Regents On Behalf Of Arizona State University Volatile biomarkers for discriminating valley fever from other lung infections

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CN115867668A (zh) * 2020-07-01 2023-03-28 国际商业机器公司 下采样基因组序列数据
CN115867668B (zh) * 2020-07-01 2025-05-02 国际商业机器公司 下采样基因组序列数据

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JP2022126644A (ja) 2022-08-30
EP4424840A1 (en) 2024-09-04
WO2018048960A1 (en) 2018-03-15
JP7394169B2 (ja) 2023-12-07
EP3510173A4 (en) 2020-05-20
CA3033241A1 (en) 2018-03-15
AU2017324949B2 (en) 2024-05-23
JP2019528697A (ja) 2019-10-17
US20210355524A1 (en) 2021-11-18
EP3510173A1 (en) 2019-07-17
US20190330680A1 (en) 2019-10-31
AU2017324949A1 (en) 2019-02-28

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