CN109689892A - 用于检测寻常型间质性肺炎的方法和系统 - Google Patents
用于检测寻常型间质性肺炎的方法和系统 Download PDFInfo
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- CN109689892A CN109689892A CN201780055050.1A CN201780055050A CN109689892A CN 109689892 A CN109689892 A CN 109689892A CN 201780055050 A CN201780055050 A CN 201780055050A CN 109689892 A CN109689892 A CN 109689892A
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Data Mining & Analysis (AREA)
- Medical Informatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Evolutionary Biology (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Software Systems (AREA)
- Evolutionary Computation (AREA)
- Artificial Intelligence (AREA)
- Bioethics (AREA)
- Epidemiology (AREA)
- Databases & Information Systems (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Pulmonology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662384609P | 2016-09-07 | 2016-09-07 | |
| US62/384,609 | 2016-09-07 | ||
| US201762528899P | 2017-07-05 | 2017-07-05 | |
| US62/528,899 | 2017-07-05 | ||
| PCT/US2017/050358 WO2018048960A1 (en) | 2016-09-07 | 2017-09-06 | Methods and systems for detecting usual interstitial pneumonia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109689892A true CN109689892A (zh) | 2019-04-26 |
Family
ID=61562790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780055050.1A Pending CN109689892A (zh) | 2016-09-07 | 2017-09-06 | 用于检测寻常型间质性肺炎的方法和系统 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20190330680A1 (enExample) |
| EP (2) | EP4424840A1 (enExample) |
| JP (2) | JP2019528697A (enExample) |
| CN (1) | CN109689892A (enExample) |
| AU (1) | AU2017324949B2 (enExample) |
| CA (1) | CA3033241A1 (enExample) |
| WO (1) | WO2018048960A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115867668A (zh) * | 2020-07-01 | 2023-03-28 | 国际商业机器公司 | 下采样基因组序列数据 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1874962A2 (en) | 2005-04-14 | 2008-01-09 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
| EP2605018A1 (en) | 2006-03-09 | 2013-06-19 | The Trustees of the Boston University | Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells |
| CN101990577A (zh) | 2007-09-19 | 2011-03-23 | 波士顿大学理事会 | 鉴定肺病药物开发的新途径 |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| JP6078339B2 (ja) | 2009-05-07 | 2017-02-08 | ベラサイト インコーポレイテッド | 甲状腺状態の診断のための方法および組成物 |
| US10526655B2 (en) | 2013-03-14 | 2020-01-07 | Veracyte, Inc. | Methods for evaluating COPD status |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| EP3770274A1 (en) | 2014-11-05 | 2021-01-27 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| US10927417B2 (en) | 2016-07-08 | 2021-02-23 | Trustees Of Boston University | Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions |
| EP3886696A4 (en) * | 2018-11-29 | 2022-08-24 | SomaLogic Operating Co., Inc. | Methods for determining disease risk combining downsampling of class-imbalanced sets with survival analysis |
| WO2020132520A2 (en) * | 2018-12-20 | 2020-06-25 | Veracyte, Inc. | Methods and systems for detecting genetic fusions to identify a lung disorder |
| WO2020176620A1 (en) * | 2019-02-26 | 2020-09-03 | Tempus | Systems and methods for using sequencing data for pathogen detection |
| EP3994696B1 (en) * | 2019-07-03 | 2025-05-14 | BostonGene Corporation | Systems and methods for sample preparation, sample sequencing, and sequencing data bias correction and quality control |
| AU2020368546A1 (en) * | 2019-10-16 | 2022-05-26 | Icahn School Of Medicine At Mount Sinai | Systems and methods for detecting a disease condition |
| US20240087690A1 (en) * | 2020-05-12 | 2024-03-14 | Synaptic, ApS | An individualized group testing method for medical test samples |
| US20240277807A1 (en) * | 2021-06-11 | 2024-08-22 | Acceleron Pharma Inc. | Actrii proteins and uses thereof |
| WO2025117806A1 (en) * | 2023-11-30 | 2025-06-05 | Arizona Board Of Regents On Behalf Of Arizona State University | Volatile biomarkers for discriminating valley fever from other lung infections |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120329666A1 (en) * | 2009-10-05 | 2012-12-27 | Duke University | Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia and Methods of Use |
| US20140329251A1 (en) * | 2011-12-09 | 2014-11-06 | Pronota N.V. | Ltbp2 as a biomarker for lung injury |
| CN104334744A (zh) * | 2012-03-27 | 2015-02-04 | 弗·哈夫曼-拉罗切有限公司 | 预测、诊断和治疗特发性肺纤维化的方法 |
| CN105247075A (zh) * | 2013-03-15 | 2016-01-13 | 维拉赛特股份有限公司 | 用于诊断肺病的生物标记物及其使用方法 |
| CN105378104A (zh) * | 2013-03-15 | 2016-03-02 | 威拉赛特公司 | 用于样品分类的方法和组合物 |
| WO2016073768A1 (en) * | 2014-11-05 | 2016-05-12 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795782A (en) | 1995-03-17 | 1998-08-18 | President & Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
| US7258838B2 (en) | 1999-06-22 | 2007-08-21 | President And Fellows Of Harvard College | Solid state molecular probe device |
| JP2003502166A (ja) | 1999-06-22 | 2003-01-21 | プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ | 固体状態の次元的特徴の制御 |
| WO2006028508A2 (en) | 2004-03-23 | 2006-03-16 | President And Fellows Of Harvard College | Methods and apparatus for characterizing polynucleotides |
| JP4533015B2 (ja) | 2004-06-15 | 2010-08-25 | キヤノン株式会社 | 化合物及びそれを用いた有機エレクトロルミネッセンス素子 |
| EP1784754A4 (en) | 2004-08-13 | 2009-05-27 | Harvard College | OPTI-NANOPORE DNA READING PLATFORM WITH ULTRAHOLE THROUGHPUT |
-
2017
- 2017-09-06 AU AU2017324949A patent/AU2017324949B2/en active Active
- 2017-09-06 EP EP24166148.7A patent/EP4424840A1/en not_active Withdrawn
- 2017-09-06 WO PCT/US2017/050358 patent/WO2018048960A1/en not_active Ceased
- 2017-09-06 JP JP2019511497A patent/JP2019528697A/ja active Pending
- 2017-09-06 CN CN201780055050.1A patent/CN109689892A/zh active Pending
- 2017-09-06 CA CA3033241A patent/CA3033241A1/en active Pending
- 2017-09-06 EP EP17849490.2A patent/EP3510173A4/en not_active Withdrawn
-
2019
- 2019-03-05 US US16/292,573 patent/US20190330680A1/en not_active Abandoned
-
2021
- 2021-03-30 US US17/218,123 patent/US20210355524A1/en not_active Abandoned
-
2022
- 2022-05-19 JP JP2022082508A patent/JP7394169B2/ja active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120329666A1 (en) * | 2009-10-05 | 2012-12-27 | Duke University | Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia and Methods of Use |
| US20140329251A1 (en) * | 2011-12-09 | 2014-11-06 | Pronota N.V. | Ltbp2 as a biomarker for lung injury |
| CN104334744A (zh) * | 2012-03-27 | 2015-02-04 | 弗·哈夫曼-拉罗切有限公司 | 预测、诊断和治疗特发性肺纤维化的方法 |
| CN105247075A (zh) * | 2013-03-15 | 2016-01-13 | 维拉赛特股份有限公司 | 用于诊断肺病的生物标记物及其使用方法 |
| CN105378104A (zh) * | 2013-03-15 | 2016-03-02 | 威拉赛特公司 | 用于样品分类的方法和组合物 |
| WO2016073768A1 (en) * | 2014-11-05 | 2016-05-12 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
Non-Patent Citations (1)
| Title |
|---|
| SU YEON KIM等: "Classifi cation of usual interstitial pneumonia in patients with", 《LANCET RESPIR MED》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115867668A (zh) * | 2020-07-01 | 2023-03-28 | 国际商业机器公司 | 下采样基因组序列数据 |
| CN115867668B (zh) * | 2020-07-01 | 2025-05-02 | 国际商业机器公司 | 下采样基因组序列数据 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA3033241A1 (en) | 2018-03-15 |
| JP2022126644A (ja) | 2022-08-30 |
| WO2018048960A1 (en) | 2018-03-15 |
| JP2019528697A (ja) | 2019-10-17 |
| JP7394169B2 (ja) | 2023-12-07 |
| EP3510173A4 (en) | 2020-05-20 |
| US20190330680A1 (en) | 2019-10-31 |
| US20210355524A1 (en) | 2021-11-18 |
| AU2017324949B2 (en) | 2024-05-23 |
| EP3510173A1 (en) | 2019-07-17 |
| EP4424840A1 (en) | 2024-09-04 |
| AU2017324949A1 (en) | 2019-02-28 |
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