CN109674879A - A kind of spray and preparation method thereof for treating rhinitis - Google Patents
A kind of spray and preparation method thereof for treating rhinitis Download PDFInfo
- Publication number
- CN109674879A CN109674879A CN201910157838.4A CN201910157838A CN109674879A CN 109674879 A CN109674879 A CN 109674879A CN 201910157838 A CN201910157838 A CN 201910157838A CN 109674879 A CN109674879 A CN 109674879A
- Authority
- CN
- China
- Prior art keywords
- parts
- spray
- rhinitis
- cordate houttuynia
- treating rhinitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
Abstract
The invention discloses a kind of sprays and preparation method thereof for treating rhinitis, a kind of spray for treating rhinitis, is made of raw material from the following weight: 2000 parts of cordate houttuynia, 25 parts of glycerol, 50 parts of full gear ethyl alcohol, 1.5 parts of Tween-80,2 parts of potassium sorbate.A kind of production method of spray for treating rhinitis, comprises the following steps that: step 1: cordate houttuynia is placed in cucurbit by distillation, and heating distills and collects just distillate；Step 2: redistillation is added glycerol, full gear ethyl alcohol, Tween-80, potassium sorbate after carrying out redistillation to first distillate, is uniformly mixed, obtains medicament；Step 3: bottling.The present invention has clearing heat and detoxicating, moisten, cleaning nasal cavity the effect of, for treating caused by rhinitis nasal obstruction, sneezing, the symptoms such as the excessive, mycteroxerosis of nasal mucus.
Description
Technical field
The present invention relates to medical sanitary technology fields, and in particular to a kind of spray and preparation method thereof for treating rhinitis.
Background technique
Rhinitis, that is, nasal cavity inflammatory disease is virus, bacterium, allergen, various physical and chemical factors and certain systemic diseases
The inflammation of caused bronchia mucosal.The main pathological change of rhinitis is bronchia mucosal hyperemia, swelling, exudation, hyperplasia, atrophy or bad
It waits indefinitely.
Rhinitis interferes the symptoms such as to breathe and cause headache brain swollen, influences work and rest, the state of an illness is more painful, the prior art
In be not also it is obvious that some long-time services easily cause the pairs such as rhinitis medicamentosa to the various treatment methods and effect of drugs of the disease
Effect, and it is easy to produce antibody, rhinitis cannot be effectively treated very well, and present many rhinitis drug prices all compare in addition
Height, patients with rhinitis will spend higher medical expenses under the premise of cannot be guaranteed to have good therapeutic effect, therefore, develop
New rhinitis drug is one of the important direction of scientific rersearch of people all the time.
Summary of the invention
For above-mentioned technical deficiency, the object of the present invention is to provide a kind of sprays and its production for treating rhinitis
Method, has clearing heat and detoxicating, moisten, cleaning nasal cavity the effect of, for treat caused by rhinitis nasal obstruction, sneeze, nasal mucus is excessive,
The symptoms such as mycteroxerosis.
In order to solve the above technical problems, the present invention adopts the following technical scheme:
A kind of spray for treating rhinitis, is made of raw material from the following weight: 2000 parts of cordate houttuynia, takes off 25 parts of glycerol
50 parts of aldehyde ethyl alcohol, 1.5 parts of Tween-80,2 parts of potassium sorbate.
A kind of production method of spray that treating rhinitis, comprises the following steps that:
Step 1: cordate houttuynia is placed in cucurbit by distillation, adds water to submerge cordate houttuynia surface, and heating is distilled and collected
First distillate；
Step 2: glycerol, full gear ethyl alcohol, Tween-80, mountain is added after carrying out redistillation to first distillate in redistillation
Potassium sorbate is uniformly mixed, obtains medicament；
Step 3: medicament described in step 2 is fitted into nose spray bottle by bottling.
Have clearing heat and detoxicating the beneficial effects of the present invention are: the present invention, moisten, cleaning nasal cavity the effect of, for treating
The symptoms such as nasal obstruction caused by rhinitis, sneezing, the excessive, mycteroxerosis of nasal mucus.
Specific embodiment
A kind of spray for treating rhinitis, is made of raw material from the following weight: 2000 parts of cordate houttuynia, takes off 25 parts of glycerol
50 parts of aldehyde ethyl alcohol, 1.5 parts of Tween-80,2 parts of potassium sorbate.
A kind of production method of spray that treating rhinitis, comprises the following steps that:
Step 1: cordate houttuynia is placed in cucurbit by distillation, adds water to submerge cordate houttuynia surface, and heating is distilled and collected
First distillate；
Step 2: glycerol, full gear ethyl alcohol, Tween-80, mountain is added after carrying out redistillation to first distillate in redistillation
Potassium sorbate is uniformly mixed, obtains medicament；
Step 3: medicament described in step 2 is fitted into nose spray bottle by bottling.
This spray is not suitable for infant patient.
The present invention has clearing heat and detoxicating, moisten, cleaning nasal cavity the effect of, for treat caused by rhinitis nasal obstruction, sneeze,
The symptoms such as the excessive, mycteroxerosis of nasal mucus.
Obviously, various changes and modifications can be made to the invention without departing from essence of the invention by those skilled in the art
Mind and range.In this way, if these modifications and changes of the present invention belongs to the range of the claims in the present invention and its equivalent technologies
Within, then the present invention is also intended to include these modifications and variations.
Claims (2)
1. a kind of spray for treating rhinitis, which is characterized in that be made of raw material from the following weight: 2000 parts of cordate houttuynia, sweet
Oily 25 parts, 50 parts of full gear ethyl alcohol, 1.5 parts of Tween-80,2 parts of potassium sorbate.
2. a kind of production method for the spray for treating rhinitis, which is characterized in that comprise the following steps that:
Step 1: cordate houttuynia is placed in cucurbit by distillation, adds water to submerge cordate houttuynia surface, and heating distills and collects just steaming
Distillate；
Step 2: glycerol, full gear ethyl alcohol, Tween-80, sorbic acid is added after carrying out redistillation to first distillate in redistillation
Potassium is uniformly mixed, obtains medicament；
Step 3: medicament described in step 2 is fitted into nose spray bottle by bottling.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910157838.4A CN109674879A (en) | 2019-03-02 | 2019-03-02 | A kind of spray and preparation method thereof for treating rhinitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910157838.4A CN109674879A (en) | 2019-03-02 | 2019-03-02 | A kind of spray and preparation method thereof for treating rhinitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109674879A true CN109674879A (en) | 2019-04-26 |
Family
ID=66197402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910157838.4A Pending CN109674879A (en) | 2019-03-02 | 2019-03-02 | A kind of spray and preparation method thereof for treating rhinitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109674879A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112057609A (en) * | 2020-09-28 | 2020-12-11 | 浙江丽能生物医药科技有限公司 | MOA lysozyme nasal spray preparation and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048784A (en) * | 2009-11-10 | 2011-05-11 | 董根荣 | Spray for treating rhinitis and preparation method thereof |
-
2019
- 2019-03-02 CN CN201910157838.4A patent/CN109674879A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048784A (en) * | 2009-11-10 | 2011-05-11 | 董根荣 | Spray for treating rhinitis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 汤杰等: "鱼腥草鼻用喷雾剂急性毒性、局部刺激性及过敏性的实验研究", 《中南药学》 * |
| 汤杰等: "鱼腥草鼻用喷雾剂拮抗大鼠实验性鼻炎的药效学研究", 《中国医院药学杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112057609A (en) * | 2020-09-28 | 2020-12-11 | 浙江丽能生物医药科技有限公司 | MOA lysozyme nasal spray preparation and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190426 |