CN109674837A - A kind of Radix Notoginseng medicinal extract extraction process - Google Patents
A kind of Radix Notoginseng medicinal extract extraction process Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A61K2236/10—Preparation or pretreatment of starting material
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
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- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a kind of Radix Notoginseng medicinal extract extraction process, the present invention is the following steps are included: a. cleans Radix Notoginseng raw material；B. Radix Notoginseng raw material is carried out dry for the first time；C. Radix Notoginseng raw material is cut；D. second of drying is carried out to Radix Notoginseng raw material；E. Radix Notoginseng raw material is crushed；F. concentration is extracted to Radix Notoginseng raw material；Using blasting ozone in service sink, it carries out disinfection to Radix Notoginseng blade, Radix Notoginseng stem and sanchi flower, spending for Radix Notoginseng individually carries out ozonization simultaneously, disinfecting times different from cauline leaf using flower in this way, and clear water is cooperated to clean, whole strain Radix Notoginseng is effectively eliminated after being cleaned, the pesticide residue of each portion faces is by effective cleaning removal, the content of beary metal in plant is removed simultaneously, it, can be from wash phase it is prevented that the residual of harmful substance compared with ethyl alcohol cleaning；Achieve the purpose that efficiently to remove the pesticide residue and content of beary metal in Notogineng Extract with extremely simple step.
Description
Technical field
The present invention relates to a kind of extraction processes, are that a kind of Radix Notoginseng medicinal extract extraction process is further specifically
A kind of reduction agriculture is residual, content of beary metal Radix Notoginseng medicinal extract extraction process.
Background technique
Radix Notoginseng, Chinese medicine name.Main product is Araliaceae three in Yunnan Wenshan Prefecture, therefore named mountain of papers Radix Notoginseng, also known as literary state Radix Notoginseng
Seven dry root and rhizome.Excavation before autumn, the flowers are in blossom, is cleaned, and separates main root, branch root and rhizome, dry.Supporting root, which is practised, claims " rib ",
Rhizome, which is practised, claims " clip ".
It is all the root for only extracting Radix Notoginseng that common Radix Notoginseng, which is extracted, for sanchi flower and leaf be not used as effective component into
Row extracts, and common extraction process may remain some pesticides and heavy metal during cleaning and extracting concentration,
So after extraction, also can remains of pesticide and heavy metal, although it is residual to reduce to greatest extent agriculture after certain process
And content of beary metal, but common activity time is long, while complex process, is easy to appear more careless mistake.
Summary of the invention
The purpose of the present invention is to provide a kind of Radix Notoginseng medicinal extract extraction processes, efficiently remove three with extremely simple step to reach
The purpose of pesticide residue and content of beary metal in seven extracts.
In order to achieve the above object, the present invention uses following technological means:
A kind of Radix Notoginseng medicinal extract extraction process, comprising the following steps:
A. Radix Notoginseng raw material is cleaned；
B. Radix Notoginseng raw material is carried out dry for the first time；
C. Radix Notoginseng raw material is cut；
D. second of drying is carried out to Radix Notoginseng raw material；
E. Radix Notoginseng raw material is crushed；
F. concentration is extracted to Radix Notoginseng raw material.
Preferably, Radix Notoginseng raw material, which is put into service sink, to be cleaned, by into the service sink in the step a
It is passed through ozone to clean the Radix Notoginseng raw material in the service sink, clear water of the Radix Notoginseng raw material soaking in the service sink
In.
Further, it is uniformly passed through 5-8g ozone per hour in the service sink of every 1m3.
Further, the Radix Notoginseng raw material separates the flower of Radix Notoginseng raw material before being put into the service sink, the Radix Notoginseng
For the stem and leaf of raw material by ozone clean 10-20min, the flower after separation passes through ozone clean 30-40min.
Further, in the step b, the dry first time is that room temperature air-dries drying, will be clear in the step a
The flower separation of rear Radix Notoginseng raw material is washed, the colored room temperature air-dries dry 10-20min, and the stem and leaf room temperature of the Radix Notoginseng raw material air-dry
Dry 5-15min.
Further, in the step c, the cutting process includes separating the cauline leaf flower of Radix Notoginseng raw material,
After separation, the stem of the Radix Notoginseng raw material is prescinded, after prescinding, the length of the stem is in 0.5-1cm.
Further, in the step d, it is that vacuum drying oven is dry, and is carrying out vacuum that described second dry
The Radix Notoginseng raw material flower, stem, leaf are separated before dry, the leaf is dried in vacuo 2-6h, and the flower and stem are dried in vacuo 10-
14h, the vacuum drying temperature are 40-80 DEG C.
Further, in the step e, the pulverising step is crushed using disintegrating apparatus, Radix Notoginseng after crushing
For the mesh number of raw material in 40-80 mesh, smashed Radix Notoginseng raw material includes following parts by weight material: Radix Notoginseng raw material flower 5-15 parts, Radix Notoginseng
65-75 parts of raw material stem, 15-25 parts of Radix Notoginseng raw material leaf.
Further, in the step f, the extraction concentration step includes extraction step, the extraction step packet
It includes and extracts and extract for the second time for the first time, the first time extracts: 45-55kg water being added after 10-20kg Radix Notoginseng raw material is crushed
The first mixed serum is made in stirring, and first mixed serum is added in extractor and carries out first time extraction, and Extracting temperature is
40-80 DEG C, extraction time 30-120min, the first solid content and first is obtained by filtration in first mixed serum after extraction
Filtered fluid；Second of extraction: being added 25-35kg water for first solid content again, and the second mixed serum is made in stirring,
Second mixed serum is added in extractor and carries out second of extraction, Extracting temperature is 40-80 DEG C, extraction time 30-
After extraction the second solid content and the second filtered fluid is obtained by filtration in second mixed serum by 120min；Described first is filtered
Liquid and second filtered fluid are mixed to prepare concentrate, and the concentrate is added in concentration tank and is concentrated.
Further, in the step f, the extraction concentration step includes concentration step, and the step e is crushed
Mixed Radix Notoginseng raw material is mixed with water, filters the mixing liquid of Radix Notoginseng raw material and water after extraction, obtains solution to be concentrated, is carried out
The concentration step, the concentration step concentration time are 50-90min, and thickening temperature is 40-80 DEG C, described to dense after concentration
The water content of contracting liquid is 15%-30%.
The present invention at least has one of following beneficial effect compared with common Radix Notoginseng extraction process:
1, it using ozone is blasted in service sink, carries out disinfection to Radix Notoginseng blade, Radix Notoginseng stem and sanchi flower, while the flower of Radix Notoginseng
Ozonization, disinfecting times different from cauline leaf using flower so are individually carried out, and clear water is cooperated to clean, is effectively eliminated
For whole strain Radix Notoginseng after being cleaned, the pesticide residue of each portion faces removes plant by effective cleaning removal
In content of beary metal, with ethyl alcohol cleaning compared with, can be from wash phase it is prevented that the residual of harmful substance；
2, the Radix Notoginseng plant after cleaning is entered the wind into separate drying, and air-dries drying using room temperature, can guarantee that Radix Notoginseng is planted in this way
By after drying, internal composition not will receive the influence of high temperature, that is, the flower of Radix Notoginseng is taken for strain, and independent room temperature air-dries dry
It is dry, allow the drying effect of sanchi flower more preferable in this way, occur when preventing volume drying cauline leaf it is dry excessively or spend not by
To completely dry problem；
3, material is carried out using vacuum drying second dry, second is dry using vacuum drying, when vacuum drying, Radix Notoginseng
Leaf is individually dried in vacuo, flower be dried in vacuo again with stem, in this way according to leaf, stem, spend respective characteristic, with it is optimal very
Empty drying time allows in Radix Notoginseng plant in the case that respective benefit materials are not destroyed reduction in guaranteeing leaf, stem, spending
Content of beary metal is greatly lowered；
4, after being dried in vacuo, the flower, stem, leaf of Radix Notoginseng plant are subjected to co-grinding, benefit after co-grinding according to a certain percentage
With extracting twice, the beneficiating ingredient in Radix Notoginseng plant is extracted in a solvent, using concentration, reduces the water content of extracting solution
Afterwards, residual, heavy metal the Radix Notoginseng medicinal extract without containing agriculture is obtained.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
Embodiment 1
A kind of Radix Notoginseng medicinal extract extraction process, comprising the following steps:
A. Radix Notoginseng raw material is cleaned；In the step a, Radix Notoginseng raw material, which is put into service sink, to be cleaned, by into the service sink
It is passed through ozone to clean the Radix Notoginseng raw material in the service sink, clear water of the Radix Notoginseng raw material soaking in the service sink
In, in general, using 3m3Service sink Radix Notoginseng raw material clean while according to every 1m3The service sink in per hour
The draft speed for being uniformly passed through 5g ozone carries out ozone bubbles cleaning to the Radix Notoginseng raw material in service sink；Radix Notoginseng raw material is being put simultaneously
The flower of Radix Notoginseng raw material is separated before entering the service sink, that is, colored stem and leaf with Radix Notoginseng is cleaned separately, aforementioned Radix Notoginseng is former
For the stem and leaf of material by ozone clean 10min, the flower after separation passes through ozone clean 30min.
In this way using ozone is blasted in service sink, carry out disinfection to Radix Notoginseng blade, Radix Notoginseng stem and sanchi flower, while three
Seven spend individually carries out ozonization, disinfecting times different from cauline leaf using flower in this way, and clear water is cooperated to clean, effectively
Whole strain Radix Notoginseng is eliminated after being cleaned, the pesticide residue of each portion faces by effective cleaning removal, is gone simultaneously
Except the content of beary metal in plant can be from wash phase it is prevented that the residual of harmful substance compared with ethyl alcohol cleaning；
B. Radix Notoginseng raw material is carried out dry for the first time；Dry aforementioned first time is that room temperature air-dries drying, after cleaning in step a
Radix Notoginseng raw material keeps the colored separation with cauline leaf, and the flower room temperature of aforementioned Radix Notoginseng raw material air-dries dry 10min, the stem of the Radix Notoginseng raw material
Dry 5min is air-dried with leaf room temperature.
The Radix Notoginseng plant after cleaning is entered the wind into separate drying in this way, and air-dries drying using room temperature, can be guaranteed in this way
After Radix Notoginseng plant is dried, internal composition not will receive the influence of high temperature, that is, the flower of Radix Notoginseng be taken, independent room temperature
Drying is air-dried, allows the drying effect of sanchi flower more preferable in this way, occur cauline leaf drying when preventing volume drying excessively or is spent
The problem that do not dried completely；
C. Radix Notoginseng raw material is cut；In order to facilitate the vacuum drying in Radix Notoginseng plant later period, allow vacuum drying effect more
It is good, cutting process is carried out to the stem of Radix Notoginseng raw material, cutting process includes separating the cauline leaf flower of Radix Notoginseng raw material, after separation,
The stem of the Radix Notoginseng raw material is prescinded, after prescinding, the length of the stem is controlled in 0.5cm or so.
D. second of drying is carried out to Radix Notoginseng raw material；It is that vacuum drying oven is dry, and is carrying out that second above-mentioned dry
The Radix Notoginseng raw material flower, stem, leaf are separated before vacuum drying, the leaf is dried in vacuo 2h, and the flower is dried in vacuo with stem
10h, the vacuum drying temperature are 40 DEG C.
Material is carried out using vacuum drying second dry, second is dry using vacuum drying, when vacuum drying, three
Seven leaves are individually dried in vacuo, flower be dried in vacuo again with stem, in this way according to leaf, stem, spend respective characteristic, use is optimal
Vacuum drying time allows in Radix Notoginseng plant in the case that respective benefit materials are not destroyed reduction in guaranteeing leaf, stem, spending
Content of beary metal be greatly lowered；
E. Radix Notoginseng raw material is crushed；And crush purpose for convenience of subsequent extraction concentration step, can be effective after crushing
Increase Radix Notoginseng raw material and extracting solution contact surface area, can effectively increase the effect and speed of extraction, but such as fruit powder
It is too smallly broken, it will increase the difficulty of filtering in filtering, and if crushing is excessive, and the effect promoting that will cause extraction is unknown
Aobvious, so in the art in abovementioned steps e, the pulverising step is crushed using disintegrating apparatus, and disintegrating apparatus can be with
It is the equipment that high-speed mixer etc. has crushing function, the mesh number of Radix Notoginseng raw material is in 60 mesh or so, smashed Radix Notoginseng after crushing
Raw material includes following parts by weight material: Radix Notoginseng raw material spends 5 parts, 65 parts of Radix Notoginseng raw material stem, 15 parts of Radix Notoginseng raw material leaf, in this way by Radix Notoginseng
Flower, stem, the leaf of raw material are mixed according to a certain percentage, and after crushing, medicinal extract obtained can have very after extracting concentration
Good nutritive value；
F. concentration is extracted to Radix Notoginseng raw material；Extraction concentration step above-mentioned includes extraction step, and the extraction step includes
It extracts for the first time and second is extracted, the first time extracts: the stirring of 45kg water being added after 10kg Radix Notoginseng raw material is crushed and is made
First mixed serum is added in extractor and carries out first time extraction by the first mixed serum, and Extracting temperature is 40 DEG C, extracts
Time is 30-60min, is specifically as follows 50min, and the first solid content and is obtained by filtration in first mixed serum after extraction
One filtered fluid；Second of extraction: being added 25kg water for first solid content again, and the second mixed serum is made in stirring,
Second mixed serum is added in extractor and carries out second of extraction, Extracting temperature is 40 DEG C, extraction time 30-60min, tool
Body can be 50min, and the second solid content and the second filtered fluid is obtained by filtration in second mixed serum after extraction；By described
One filtered fluid and second filtered fluid are mixed to prepare concentrate, and the concentrate is added in concentration tank and is concentrated, is passed through in this way
It extracts twice, can effectively increase the effect entirely extracted, the beneficiating ingredient in Radix Notoginseng plant is allowed largely to be suggested, it is aforementioned
Extraction concentration step include concentration step, the liquid after extracting twice be solution to be concentrated, carry out the concentration step, institute
Stating concentration step concentration time is 50min, and thickening temperature is 40 DEG C, and the water content of the solution to be concentrated is 30% after concentration.
After being dried in vacuo in this way, the flower, stem, leaf of Radix Notoginseng plant are subjected to co-grinding, mixed powder according to a certain percentage
Using extracting twice after broken, the beneficiating ingredient in Radix Notoginseng plant is extracted in a solvent, using concentration, reduces the water of extracting solution
After content, residual, heavy metal the Radix Notoginseng medicinal extract without containing agriculture is obtained.
Embodiment 2
A kind of Radix Notoginseng medicinal extract extraction process, comprising the following steps:
A. Radix Notoginseng raw material is cleaned；In the step a, Radix Notoginseng raw material, which is put into service sink, to be cleaned, by into the service sink
It is passed through ozone to clean the Radix Notoginseng raw material in the service sink, clear water of the Radix Notoginseng raw material soaking in the service sink
In, in general, using 3m3Service sink Radix Notoginseng raw material clean while according to every 1m3The service sink in per hour
The draft speed for being uniformly passed through 8g ozone carries out ozone bubbles cleaning to the Radix Notoginseng raw material in service sink；Radix Notoginseng raw material is being put simultaneously
The flower of Radix Notoginseng raw material is separated before entering the service sink, that is, colored stem and leaf with Radix Notoginseng is cleaned separately, aforementioned Radix Notoginseng is former
For the stem and leaf of material by ozone clean 20min, the flower after separation passes through ozone clean 40min.
In this way using ozone is blasted in service sink, carry out disinfection to Radix Notoginseng blade, Radix Notoginseng stem and sanchi flower, while three
Seven spend individually carries out ozonization, disinfecting times different from cauline leaf using flower in this way, and clear water is cooperated to clean, effectively
Whole strain Radix Notoginseng is eliminated after being cleaned, the pesticide residue of each portion faces by effective cleaning removal, is gone simultaneously
Except the content of beary metal in plant can be from wash phase it is prevented that the residual of harmful substance compared with ethyl alcohol cleaning；
B. Radix Notoginseng raw material is carried out dry for the first time；Dry aforementioned first time is that room temperature air-dries drying, after cleaning in step a
Radix Notoginseng raw material keeps the colored separation with cauline leaf, and the flower room temperature of aforementioned Radix Notoginseng raw material air-dries dry 20min, the stem of the Radix Notoginseng raw material
Dry 15min is air-dried with leaf room temperature.
The Radix Notoginseng plant after cleaning is entered the wind into separate drying in this way, and air-dries drying using room temperature, can be guaranteed in this way
After Radix Notoginseng plant is dried, internal composition not will receive the influence of high temperature, that is, the flower of Radix Notoginseng be taken, independent room temperature
Drying is air-dried, allows the drying effect of sanchi flower more preferable in this way, occur cauline leaf drying when preventing volume drying excessively or is spent
The problem that do not dried completely；
C. Radix Notoginseng raw material is cut；In order to facilitate the vacuum drying in Radix Notoginseng plant later period, allow vacuum drying effect more
It is good, cutting process is carried out to the stem of Radix Notoginseng raw material, cutting process includes separating the cauline leaf flower of Radix Notoginseng raw material, after separation,
The stem of the Radix Notoginseng raw material is prescinded, after prescinding, the length of the stem is controlled in 1cm or so.
D. second of drying is carried out to Radix Notoginseng raw material；It is that vacuum drying oven is dry, and is carrying out that second above-mentioned dry
The Radix Notoginseng raw material flower, stem, leaf are separated before vacuum drying, the leaf is dried in vacuo 6h, and the flower is dried in vacuo with stem
14h, the vacuum drying temperature are 82 DEG C.
Material is carried out using vacuum drying second dry, second is dry using vacuum drying, when vacuum drying, three
Seven leaves are individually dried in vacuo, flower be dried in vacuo again with stem, in this way according to leaf, stem, spend respective characteristic, use is optimal
Vacuum drying time allows in Radix Notoginseng plant in the case that respective benefit materials are not destroyed reduction in guaranteeing leaf, stem, spending
Content of beary metal be greatly lowered；
E. Radix Notoginseng raw material is crushed；And crush purpose for convenience of subsequent extraction concentration step, can be effective after crushing
Increase Radix Notoginseng raw material and extracting solution contact surface area, can effectively increase the effect and speed of extraction, but such as fruit powder
It is too smallly broken, it will increase the difficulty of filtering in filtering, and if crushing is excessive, and the effect promoting that will cause extraction is unknown
Aobvious, so in the art in abovementioned steps e, the pulverising step is crushed using disintegrating apparatus, and disintegrating apparatus can be with
It is the equipment that high-speed mixer etc. has crushing function, the mesh number of Radix Notoginseng raw material is in 80 mesh or so, smashed Radix Notoginseng after crushing
Raw material includes following parts by weight material: Radix Notoginseng raw material spends 15 parts, 75 parts of Radix Notoginseng raw material stem, 25 parts of Radix Notoginseng raw material leaf, in this way by three
Flower, stem, the leaf of seven raw materials are mixed according to a certain percentage, and after crushing, medicinal extract obtained can have after extracting concentration
Good nutritive value；
F. concentration is extracted to Radix Notoginseng raw material；Extraction concentration step above-mentioned includes extraction step, and the extraction step includes
It extracts for the first time and second is extracted, the first time extracts: the stirring of 55kg water being added after 20kg Radix Notoginseng raw material is crushed and is made
First mixed serum is added in extractor and carries out first time extraction by the first mixed serum, and Extracting temperature is 80 DEG C, extracts
Time is 60-120min, is specifically as follows 90min, after extraction by first mixed serum be obtained by filtration the first solid content and
First filtered fluid；Second of extraction: 35kg water is added in first solid content again, the second mixing slurry is made in stirring
Second mixed serum is added in extractor and carries out second of extraction by liquid, and Extracting temperature is 40 DEG C, extraction time 60-120min,
It is specifically as follows 90min, the second solid content and the second filtered fluid is obtained by filtration in second mixed serum after extraction；It will be described
First filtered fluid and second filtered fluid are mixed to prepare concentrate, and the concentrate is added in concentration tank and is concentrated, logical in this way
It is extracted after twice, can effectively increase the effect entirely extracted, the beneficiating ingredient in Radix Notoginseng plant is allowed largely to be suggested, it is preceding
The extraction concentration step stated includes concentration step, and the liquid after extracting twice is solution to be concentrated, carries out the concentration step,
The concentration step concentration time is 90min, and thickening temperature is 80 DEG C, and the water content of the solution to be concentrated is 15% after concentration.
After being dried in vacuo in this way, the flower, stem, leaf of Radix Notoginseng plant are subjected to co-grinding, mixed powder according to a certain percentage
Using extracting twice after broken, the beneficiating ingredient in Radix Notoginseng plant is extracted in a solvent, using concentration, reduces the water of extracting solution
After content, residual, heavy metal the Radix Notoginseng medicinal extract without containing agriculture is obtained.
Although reference be made herein to invention has been described for multiple explanatory embodiments of the invention, however, it is to be understood that
Those skilled in the art can be designed that a lot of other modification and implementations, these modifications and implementations will fall in this Shen
It please be within disclosed scope and spirit.It more specifically, within the scope of the present disclosure and claims, can be to master
The building block and/or layout for inscribing composite configuration carry out a variety of variations and modifications.In addition to what is carried out to building block and/or layout
Outside modification and improvement, to those skilled in the art, other purposes also be will be apparent.
Claims (10)
1. a kind of Radix Notoginseng medicinal extract extraction process, it is characterised in that: the following steps are included:
A. Radix Notoginseng raw material is cleaned；
B. Radix Notoginseng raw material is carried out dry for the first time；
C. Radix Notoginseng raw material is cut；
D. second of drying is carried out to Radix Notoginseng raw material；
E. Radix Notoginseng raw material is crushed；
F. concentration is extracted to Radix Notoginseng raw material.
2. a kind of Radix Notoginseng medicinal extract extraction process according to claim 1, it is characterised in that: in the step a, Radix Notoginseng is former
Material, which is put into service sink, to be cleaned, and is carried out clearly by being passed through ozone into the service sink to the Radix Notoginseng raw material in the service sink
It washes, the Radix Notoginseng raw material soaking is in the clear water in the service sink.
3. a kind of Radix Notoginseng medicinal extract extraction process according to claim 2, it is characterised in that: every 1m3The service sink in it is every
Hour is uniformly passed through 5-8g ozone.
4. a kind of Radix Notoginseng medicinal extract extraction process according to claim 3, it is characterised in that: the Radix Notoginseng raw material is being put into
The flower of Radix Notoginseng raw material is separated before stating service sink, the stem and leaf of the Radix Notoginseng raw material are by ozone clean 10-20min, after separation
The flower pass through ozone clean 30-40min.
5. a kind of Radix Notoginseng medicinal extract extraction process described in any one of according to claim 1, it is characterised in that: in the step
In b, the dry first time is that room temperature air-dries drying, and the flower of Radix Notoginseng raw material separates after cleaning in the step a, described to spend often
Temperature air-dries dry 10-20min, and the stem and leaf room temperature of the Radix Notoginseng raw material air-dry dry 5-15min.
6. a kind of Radix Notoginseng medicinal extract extraction process according to claim 1, it is characterised in that: described to cut in the step c
The process of cutting includes separating the cauline leaf flower of Radix Notoginseng raw material, and after separation, the stem of the Radix Notoginseng raw material is prescinded, after prescinding, institute
The length of stem is stated in 0.5-1cm.
7. a kind of Radix Notoginseng medicinal extract extraction process according to claim 1, it is characterised in that: in the step d, described
Redrying is dry for vacuum drying oven, and separates the Radix Notoginseng raw material flower, stem, leaf before being dried in vacuo, the leaf
It is dried in vacuo 2-6h, the flower and stem are dried in vacuo 10-14h, and the vacuum drying temperature is 40-80 DEG C.
8. a kind of Radix Notoginseng medicinal extract extraction process as claimed in any of claims 1 to 7, it is characterised in that: described
In step e, the pulverising step is crushed using disintegrating apparatus, and the mesh number of Radix Notoginseng raw material is in 40-80 mesh after crushing, after crushing
Radix Notoginseng raw material include following parts by weight material: Radix Notoginseng raw material flower 5-15 parts, 65-75 parts of Radix Notoginseng raw material stem, Radix Notoginseng raw material leaf 15-
25 parts.
9. a kind of Radix Notoginseng medicinal extract extraction process as claimed in any of claims 1 to 7, it is characterised in that: described
In step f, the extraction concentration step includes extraction step, and the extraction step includes extracting and extracting for the second time for the first time,
The first time extracts: the stirring of 45-55kg water being added after 10-20kg Radix Notoginseng raw material is crushed, the first mixed serum is made, by institute
It states the first mixed serum and progress first time extraction in extractor is added, Extracting temperature is 40-80 DEG C, extraction time 30-
After extraction the first solid content and the first filtered fluid is obtained by filtration in first mixed serum by 120min；Second of extraction:
25-35kg water is added in first solid content again, the second mixed serum is made in stirring, and the second mixed serum is added and is extracted
It carries out extracting for second in tank, Extracting temperature is 40-80 DEG C, extraction time 30-120min, is mixed after extraction by described second
The second solid content and the second filtered fluid is obtained by filtration in slurries；First filtered fluid is mixed to prepare with second filtered fluid dense
The concentrate is added in concentration tank and is concentrated by contracting liquid.
10. a kind of Radix Notoginseng medicinal extract extraction process according to claim 1, it is characterised in that: described in the step f
Extracting concentration step includes concentration step, and the Radix Notoginseng raw material after the step e is pulverized and mixed is mixed with water, by Radix Notoginseng after extraction
The filtering of the mixing liquid of raw material and water, obtains solution to be concentrated, carries out the concentration step, the concentration step concentration time is
50-90min, thickening temperature are 40-80 DEG C, and the water content of the solution to be concentrated is 15%-30% after concentration.
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Citations (2)
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|---|---|---|---|---|
| CN108014154A (en) * | 2017-12-05 | 2018-05-11 | 四川金岁方药业有限公司 | A kind of method for extracting arasaponin |
| CN108835639A (en) * | 2018-08-07 | 2018-11-20 | 玉溪市维和维生堂保健食品有限公司 | A kind of Radix Notoginseng spray composition and the preparation method and application thereof |
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2019
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108014154A (en) * | 2017-12-05 | 2018-05-11 | 四川金岁方药业有限公司 | A kind of method for extracting arasaponin |
| CN108835639A (en) * | 2018-08-07 | 2018-11-20 | 玉溪市维和维生堂保健食品有限公司 | A kind of Radix Notoginseng spray composition and the preparation method and application thereof |
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