CN109646999A - It is a kind of for separating the Simulation moving bed and method of glucide - Google Patents
It is a kind of for separating the Simulation moving bed and method of glucide Download PDFInfo
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- CN109646999A CN109646999A CN201811412850.7A CN201811412850A CN109646999A CN 109646999 A CN109646999 A CN 109646999A CN 201811412850 A CN201811412850 A CN 201811412850A CN 109646999 A CN109646999 A CN 109646999A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds
- B01D15/1828—Simulated moving beds characterized by process features
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
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Abstract
The present invention is separation core with the resin with uniform particle refined, the simulated moving bed separation device and sequential separating technology for cooperating optimization can significantly improve the purity of isolated purpose product in sugar products production process, reduce the consumption of eluant, eluent water, it is beneficial to energy conservation environmental protection, reduces cost.
Description
Technical field
The present invention relates to a kind of sugared separator, in particular to a kind of Simulation moving beds and side for separating glucide
Method.
Background technique
Simulation moving bed is realized, for the separating technology of petrochemical industry, have so far earliest by Praxair Technology, Inc
More than 60 years developing histories.Conventional Simulation moving bed is end to end at a closed loop, each root chromatogram column by more root chromatogram columns
Including material inlet, eluant, eluent entrance, extracting solution (mainly containing strong absorbed component) outlet and raffinate (main group containing weakly stable
Point) outlet, Simulation moving bed device is divided by four areas according to the position of each period entrance and exit: eluant, eluent entrance and being mentioned
It takes between liquid outlet as the area I, is the area II between extracting liquid outlet and material inlet, is between material inlet and raffinate outlet
The area III is the area IV between raffinate outlet and eluant, eluent entrance.Every area at least arranges 1 root chromatogram column, in operational process, disengaging
Mouth position periodically switches along mobile phase flow direction, keeps stationary phase " simulation " and mobile phase adverse current mobile, increases liquid and consolidate
Two alternate mass transfer forces, improve separative efficiency, while avoiding the mobile caused device problem of the solid adverse current of true liquid
It is worn with stationary phase.Currently, simulated moving bed technology has been widely used in the separation neck of petroleum chemicals, food, drug etc.
Domain.
The huge market demand of sugar products (such as glucose, fructose, xylose, arabinose, trehalose), therefore produce
Unit capacity is big, and input concentration is high, since the property of substance to be separated is close, generallys use simulated moving bed technology separation,
It generally selects strong basicity cation exchange resin as filler in separation process, uses water as eluant, eluent, utilize different carbohydrates
Molecular weight or polarity difference realize separation between molecule, obtain the product of high-purity.The performance of separation resin directly determines technique
Separative efficiency, and then to product yield, eluant, eluent consumption etc. economic factors have an impact.
Prior art CN105749584A discloses a kind of method of Simulation moving bed separate substance, wherein such as Fig. 1 institute
Show, the Simulation moving bed is divided into the area I, the area II, the area III and the area IV, process sequence are as follows: (1) by the feed liquid containing A, B substance
It is injected from the area III entrance, while eluant, eluent being injected from the area I entrance, carry out four Qu Xunhuan after injection；(2) when raffinate reaches
When the area III exports, the area IV is made to stop working, then inject eluant, eluent from the area I entrance, while raffinate being exported from the area III
Discharge；(3) when the outlet of the area I, extracting solution reaches predetermined concentration, eluant, eluent is injected from the area I entrance, while by extracting solution from the area I
Outlet discharge；Feed liquid is injected from the area III entrance, while raffinate being exported from the area III and is discharged；(4) make feed liquid injection phase,
Eluant, eluent injection phase, raffinate drain position, extracting solution drain position sequentially move an area, then repeat the above steps
(1)、(2)、(3)。
It is equal due to filler however, this sequential type simulated moving bed chromatography technique used by traditional separating technology
Once insufficient and partial size was larger, is unable to satisfy separating effect, material is caused to spread in separation system seriously, and mass-transfer efficiency is low,
It needs to consume more eluant, eluents and expends more times flushings to reach expected product purity.
Summary of the invention
In view of the above problem, present invention discover that by improving sequential simulated moving bed separating technology sequence, and tie
It closes and uses uniform particle diameter and the small resin of partial size is as separating medium, realize the optimization of sugar products separation process, it can be with
The purity of isolated target product is significantly improved, while reducing the consumption of eluant, eluent.
The purpose of the present invention and benefit are achieved through the following technical solutions:
On the one hand, the present invention provides a kind of for separating the Simulation moving bed of glucide, the Simulation moving bed packet
Include the area I, the area II, the area III and the area IV of fluid communication, wherein be respectively disposed with 1-2 in the area I, the area II, the area III and the area IV
Root chromatogram column, it is the cation exchange tree that 20 μm -250 μm and coefficient of uniformity are not more than 1.10 that partial size is filled in the chromatographic column
Rouge.
On the other hand, the present invention provides a kind of methods that glucide is separated using above-mentioned Simulation moving bed, wherein
The described method includes:
(1) area I, the area II, the area III are connected to the area IV, carry out four Qu Xunhuan；
(2) when making the component A of relatively strong absorption when the outlet of the area I reaches predetermined concentration by 4th area circulation, make II
Area and the area IV stop working, and eluant, eluent are injected from the area I entrance, while outlet is emptied containing the relatively strong absorption from the area I
The extracting solution of component A；Also, feed liquid is injected from the area III entrance, while containing opposite weakly stable from the area III outlet discharge
The raffinate of component B；
(3) when the feed liquid the area III feed after, by the area I, the area II and the area III be connected to the area Bing Shi IV keep stopping
Work injects eluant, eluent from the area I entrance, meanwhile, it will not go out net raffinate and export emptying from the area III；
(4) make the injection phase of the feed liquid, the injection phase of the eluant, eluent, the drain position of the raffinate and institute
The drain position for stating extracting solution sequentially moves an area, and then repeat the above steps (1), (2) and (3).
Beneficial effect
The present invention is separation core with the resin with uniform particle (20 μm -250 μm of partial size and coefficient of uniformity is no more than 1.10) refined
The heart can be effectively reduced diffusion of the material in separation system, improve mass-transfer efficiency；In addition, due to the drop with resin partial size
It is low, the higher sugar products of solid content are separated, resin column pressure can be bigger than normal, in order to preferably play the equal grain tree of above-mentioned fining
The separation efficiency of rouge, the present invention (pass through supplement eluant, eluent in feeding process by adjusting technique after above-mentioned step 2)
(above-mentioned step 3) can play certain diluting effect to material under open loop situations, be circulated throughout to reduce subsequent closed loop
Pressure in journey in system.
The sequential simulated moving bed separating technology sequence that the present invention is optimized by cooperation, in sugar products production process
In can significantly improve the purity of isolated product, the purity of the glucide after making separation reaches food industry demand,
The consumption of eluant, eluent water is reduced, and then reduces the steam consumption of subsequent evaporation concentration, while can also efficiently recycle may packet in feed liquid
The other glucides contained, are beneficial to energy conservation environmental protection, reduce cost.
Detailed description of the invention
Present invention will be further explained below with reference to the attached drawings and examples.
Fig. 1 is the schematic diagram for the process flow that conventional Simulation moving bed separates glucide.
Fig. 2 is the schematic diagram for the process flow that illustrative Simulation moving bed of the invention separates glucide.
Specific embodiment
Below in conjunction with attached drawing, detailed description of the preferred embodiments.It should be understood that tool herein
Body embodiment is merely to illustrate and explain the present invention, and is not intended to restrict the invention.
In the present invention, term " the component A of relatively strong absorption " and " relative to the component B of weakly stable " are based on simulation movement
Bed chromatographic column in cation exchange resin for the relative different between the adsorption capacity of the two the material of the charging of determination
Component in liquid, wherein the relatively stronger component of reserve capability is known as " relatively strong absorption in the cation exchange resin
Component A "；And the relatively weaker component of reserve capability is known as " the component B of opposite weakly stable " in the cation exchange resin.
In one embodiment, the present invention relates to a kind of for separating the Simulation moving bed of glucide, the simulation
Moving bed includes the area I, the area II, the area III and the area IV being in fluid communication, wherein in the area I, the area II, the area III and the area IV respectively
It is disposed with 1-2 root chromatogram column, it is the sun that 20 μm -250 μm and coefficient of uniformity are not more than 1.10 that partial size is filled in the chromatographic column
Ion exchange resin.
It should be appreciated by those skilled in the art Simulation moving bed is according to the injection phase of feed liquid, the note of eluant, eluent
Enter position, the drain position of raffinate, extracting solution the difference of drain position be divided into the area I, the area II, the area III and the area IV.Wherein,
Eluant, eluent entrance and extracting solution (the component A mainly containing relatively strong absorption) are exported it by Simulation moving bed device according to the present invention
Between pillar region be known as the area I, the pillar region between extracting liquid outlet and feed liquid port is known as the area II, and feed liquid enters
Pillar region between mouth and raffinate (the component B mainly containing opposite weakly stable) outlet is known as the area III, raffinate outlet
Pillar region between eluant, eluent entrance is known as the area IV.
In the present invention, term " four Qu Xunhuan " refers to the process of as follows: the area I, the area II, the area III are same after being connected to the area IV
When start to work, make the feed liquid of the component B of eluant, eluent and component A containing relatively strong absorption and opposite weakly stable in the area I, II
It is flowed in area, the area III and the area IV, due to the difference of reserve capability of the different component in cation exchange resin, so as to
The component B of the component A and opposite weakly stable that realize relatively strong absorption are flowed in different areas.
Cation exchange resin in the present invention can be used conventional preparation process preparation known in the art or can adopt
With meet the present invention claims commercialized ion exchange resin, for example, can refer to following technique reported in the literature to be made
It is standby: Deng Fuxing, Wang Guoqing, Xu Hanfu；Resin with uniform particle manufacturing technology and its application on chromatographic isolation resin；Food and fermentation
Industry；2015,41 (12): 180-183.
In a preferred embodiment, the cation exchange resin includes but is not limited to calcium type, sodium form and/or potassium type tree
Rouge, preferably calcium type and/or potassium type resin.
In the present invention, unless otherwise indicated, term " coefficient of uniformity " refers to the uniform level of resin.The homogenous system of resin
Several and partial size can be used methods known in the art and be measured, for example, coefficient of uniformity and partial size can refer to " GB/T5758-
The measurements of 2001 ion exchange resin bead degree, effective grain size and coefficient of uniformity " in method measure.
In one preferred embodiment, the coefficient of uniformity of the cation exchange resin is 1.06-1.10.
In a preferred embodiment, the partial size of the cation exchange resin is 80 μm -200 μm, preferably 150 μm -200
μm, to facilitate the pressure in the area II of reduction Simulation moving bed.
In another embodiment, the present invention relates to a kind of sides that glucide is separated using above-mentioned Simulation moving bed
Method, wherein the described method includes:
(1) area I, the area II, the area III are connected to the area IV, carry out four Qu Xunhuan；
(2) when making the component A of relatively strong absorption when the outlet of the area I reaches predetermined concentration by 4th area circulation, make II
Area and the area IV stop working, and eluant, eluent are injected from the area I entrance, while outlet is emptied containing the relatively strong absorption from the area I
The extracting solution of component A；Also, feed liquid is injected from the area III entrance, while containing opposite weakly stable from the area III outlet discharge
The raffinate of component B；
(3) when the feed liquid the area III feed after, by the area I, the area II and the area III be connected to the area Bing Shi IV keep stopping
Work injects eluant, eluent from the area I entrance, meanwhile, it will not go out net raffinate and export emptying from the area III；
(4) make the injection phase of the feed liquid, the injection phase of the eluant, eluent, the drain position of the raffinate and institute
The drain position for stating extracting solution sequentially moves an area, and then repeat the above steps (1), (2) and (3).
In a preferred embodiment, the eluant, eluent is water.
In a preferred embodiment, the method carries out under 50 DEG C -80 DEG C, such as 55 DEG C -65 DEG C of operation temperature.
In addition, other separation process conditions involved in method of the invention are the Simulation moving bed separating technology of this field routine
Condition can be adjusted by those skilled in the art according to the difference of device size and practical production capacity.Moreover, side of the invention
Predetermined concentration in the step of described in method (2) is preset concentration according to needs of production, can be by this field skill
Art personnel are adjusted according to actual needs.
In the present invention, unless otherwise indicated, term " glucide " is also known as carbohydrate, refers to by C, H, O tri-
The polyhydroxy aldehyde or polyhydroxyketone compound of kind element composition, can be divided into monosaccharide, disaccharides and polysaccharide etc., illustrative glucide
Including but not limited to two or more mixed of glucose, fructose, xylose, arabinose, trehalose and psicose etc.
Object is closed, for example, mixing molasses (the preferably psicose of the psicose containing 30wt% of F42 fructose syrup, psicose and fructose
With the mixing molasses of fructose) etc..Unless otherwise indicated, " feed liquid " herein refers to comprising the molten of glucide to be separated
Liquid, glucide therein are divided into the component of relatively strong absorption according to the difference of the reserve capability in cation exchange resin
(for example, in F42 fructose syrup, fructose is the component A of relatively strong absorption to the component B of A and opposite weakly stable, and glucose is
The component B of opposite weakly stable)；Preferably, the dry solid content of the feed liquid is 50wt%-60wt%；It is preferred that the feed liquid is dry
The psicose and fructose that the F42 fructose syrup or dry solid content that solid content is 60wt% are 50wt% mixing molasses (into
One step is preferred, and dry solid content is the psicose of the psicose containing 30wt% of 50wt% and the mixing molasses of fructose).
Embodiment
Invention is further described in detail by the following examples.These embodiments are merely illustrative, without
It is construed as being to limit the scope of the present invention.All technical solutions and its change realized based on above content of the present invention
Shape is within the scope of the present invention.
In the present invention, unless otherwise indicated, term " ratio of water to material " refers between water and reduction of feed volume as eluant, eluent
Mass ratio.
Following comparative examples 1 and embodiment 1- embodiment 3 uses existing conventional simulation moving bed and of the invention respectively
Simulation moving bed is from the isolated fructose of F42 fructose syrup.
Comparative example 1 utilizes conventional simulation moving bed separating levulose
Using existing sequential simulated moving bed system, in each of which area have one loaded partial size be 310 μm and
The fixed dimension chromatographic column for the calcium type resin that coefficient of uniformity is 1.10It is the F42 fruit of 60wt% with dry solid content
Glucose slurry is used as feed liquid, and operation temperature is 60 DEG C, and eluant, eluent is water.Operating procedure as shown in Figure 1 is realized by process control,
Online pressure detector data are recorded, the purity and technique ratio of water to material of separation product are recorded, as a result such as 1 institute of table
Show.
Embodiment 1 utilizes Simulation moving bed separating levulose of the invention
Using sequential simulated moving bed system of the invention, in each of which area have one loaded partial size be 20 μm and
The fixed dimension chromatographic column for the calcium type resin that coefficient of uniformity is 1.10It is the F42 fruit of 60wt% with dry solid content
Glucose slurry is used as feed liquid, and operation temperature is 60 DEG C, and eluant, eluent is water.Operating procedure as shown in Figure 2 is realized by process control,
Online pressure detector data are recorded, the purity and technique ratio of water to material of separation product are recorded, as a result such as 1 institute of table
Show.
Embodiment 2 utilizes Simulation moving bed separating levulose of the invention
It is 250 μm that there is one to have been loaded partial size using sequential simulated moving bed system of the invention, in each of which area
And coefficient of uniformity be 1.08 calcium type resin fixed dimension chromatographic columnIt is the F42 of 60wt% with dry solid content
Fructose syrup is as feed liquid, and operation temperature is 60 DEG C, and eluant, eluent is water.Operative employee as shown in Figure 2 is realized by process control
Skill records online pressure detector data, records to the purity and technique ratio of water to material of separation product, as a result such as table
Shown in 1.
Embodiment 3 utilizes Simulation moving bed separating levulose of the invention
It is 180 μm that there is one to have been loaded partial size using sequential simulated moving bed system of the invention, in each of which area
And coefficient of uniformity be 1.06 calcium type resin fixed dimension chromatographic columnIt is the F42 of 60wt% with dry solid content
Fructose syrup is as feed liquid, and operation temperature is 60 DEG C, and eluant, eluent is water.Operative employee as shown in Figure 2 is realized by process control
Skill records online pressure detector data, records to the purity and technique ratio of water to material of separation product, as a result such as table
Shown in 1.
The Simulation moving bed of the invention of table 1 is compared with the operating condition of conventional Simulation moving bed
Following comparative examples 2 and embodiment 4- embodiment 6 uses existing conventional simulation moving bed and of the invention respectively
The isolated psicose of the mixing molasses of Simulation moving bed from psicose and fructose.
Comparative example 2 separates psicose using conventional simulation moving bed
Using existing sequential simulated moving bed system, in each of which area have one loaded partial size be 320 μm and
The fixed dimension chromatographic column for the potassium type resin that coefficient of uniformity is 1.10With dry solid content containing for 50wt%
The psicose of 30wt% psicose and the mixing molasses of fructose are as feed liquid, and operation temperature is 60 DEG C, and eluant, eluent is water.It is logical
It crosses process control and realizes operating procedure as shown in Figure 1, online pressure detector data are recorded, to the pure of separation product
Degree and technique ratio of water to material are recorded, and the results are shown in Table 2.
Embodiment 4 separates psicose using Simulation moving bed of the invention
Using sequential simulated moving bed system of the invention, in each of which area have one loaded partial size be 20 μm and
The fixed dimension chromatographic column for the potassium type resin that coefficient of uniformity is 1.10With dry solid content containing for 50wt%
The psicose of 30wt% psicose and the mixing molasses of fructose are as feed liquid, and operation temperature is 60 DEG C, and eluant, eluent is water.It is logical
It crosses process control and realizes operating procedure as shown in Figure 2, online pressure detector data are recorded, to the pure of separation product
Degree and technique ratio of water to material are recorded, and the results are shown in Table 2.
Embodiment 5 separates psicose using Simulation moving bed of the invention
It is 250 μm that there is one to have been loaded partial size using sequential simulated moving bed system of the invention, in each of which area
And coefficient of uniformity be 1.08 potassium type resin fixed dimension chromatographic columnWith dry solid content containing for 50wt%
The psicose of 30wt% psicose and the mixing molasses of fructose are as feed liquid, and operation temperature is 60 DEG C, and eluant, eluent is water.It is logical
It crosses process control and realizes operating procedure as shown in Figure 2, online pressure detector data are recorded, to the pure of separation product
Degree and technique ratio of water to material are recorded, and the results are shown in Table 2.
Embodiment 6 separates psicose using Simulation moving bed of the invention
It is 180 μm that there is one to have been loaded partial size using sequential simulated moving bed system of the invention, in each of which area
And coefficient of uniformity be 1.06 potassium type resin fixed dimension chromatographic columnWith dry solid content containing for 50wt%
The psicose of 30wt% psicose and the mixing molasses of fructose are as feed liquid, and operation temperature is 60 DEG C, and eluant, eluent is water.It is logical
It crosses process control and realizes operating procedure as shown in Figure 2, online pressure detector data are recorded, to the pure of separation product
Degree and technique ratio of water to material are recorded, and the results are shown in Table 2.
The Simulation moving bed of the invention of table 2 is compared with the operating condition of conventional Simulation moving bed
Herein, the numerical value of pressure difference after the area II column front pillar, default warning value is shown in the area II Pressure maximum value
For 5.3bar, if the area II Pressure maximum value is more than the warning value, system meeting time out program could be after reforwarding after pressure decline
Line program.And usually it will cause the area II Pressure maximum value when the partial size of cation exchange resin reduces and significantly increase and be more than
Above-mentioned warning value, but the present invention passes through the sequential simulated moving bed separating technology sequence with the use of optimization, so that
When dramatically reducing the partial size of resin cation, the area II Pressure maximum value still is able under above-mentioned warning value, from
And enable production process continuous operation.
In addition, as shown in Table 1 and Table 2, it can be seen from the comparing result of embodiment and comparative example and using greater particle size
The comparative example of resin compare, the embodiment of the present invention is exchanged by using having the cation for the partial size being within a certain range
Resin can obtain the product of higher purity and more economic ratio of water to material may be implemented.
Claims (10)
1. a kind of for separating the Simulation moving bed of glucide, the Simulation moving bed include the area I being in fluid communication, the area II,
The area III and the area IV, wherein 1-2 root chromatogram column is respectively disposed in the area I, the area II, the area III and the area IV, in the chromatographic column
Being filled with partial size is the cation exchange resin that 20 μm -250 μm and coefficient of uniformity are not more than 1.10.
2. Simulation moving bed as described in claim 1, wherein the cation exchange resin includes calcium type, sodium form and/or potassium
Type resin, preferably calcium type and/or potassium type resin.
3. Simulation moving bed as claimed in claim 1 or 2, wherein the coefficient of uniformity of the cation exchange resin is 1.06-
1.10。
4. Simulation moving bed as claimed in any one of claims 1-3, wherein the partial size of the cation exchange resin is 80
μm -200 μm, preferably 150 μm -200 μm.
5. a kind of utilize the method for separating glucide such as Simulation moving bed of any of claims 1-4, wherein
The described method includes:
(1) area I, the area II, the area III are connected to the area IV, carry out four Qu Xunhuan；
(2) when by 4th area circulation make the component A of relatively strong absorption the area I outlet reach predetermined concentration when, make the area II and
The area IV stops working, and eluant, eluent is injected from the area I entrance, while the component A for containing the relatively strong absorption is emptied from the outlet of the area I
Extracting solution；Also, feed liquid is injected from the area III entrance, while the component B from the area III outlet discharge containing opposite weakly stable
Raffinate；
(3) when the feed liquid the area III feed after, by the area I, the area II and the area III be connected to the area Bing Shi IV holding stop working,
Eluant, eluent is injected from the area I entrance, meanwhile, it will not go out net raffinate and export emptying from the area III；
(4) make the injection phase of the feed liquid, the injection phase of the eluant, eluent, the raffinate drain position and described mention
The drain position of liquid is taken sequentially to move an area, then repeat the above steps (1), (2) and (3).
6. method as claimed in claim 5, wherein the eluant, eluent is water.
7. such as method described in claim 5 or 6, wherein the method is in 50 DEG C -80 DEG C, preferably 55 DEG C -65 DEG C of operation temperature
Degree is lower to carry out.
8. the method as described in any one of claim 5-7, wherein the glucide is the mixing of psicose and fructose
Syrup or F42 fructose syrup；
Preferably, the glucide is the psicose of the psicose containing 30wt% and the mixing molasses of fructose.
9. the method as described in any one of claim 5-8, wherein the dry solid content of the feed liquid is 50wt%-60wt%.
10. such as any one of claim 5-9 the method, wherein the feed liquid is the F42 fruit Portugal that dry solid content is 60wt%
Syrup or dry solid content are the psicose of 50wt% and the mixing molasses of fructose, such as dry solid content is containing for 50wt%
The psicose of 30wt% psicose and the mixing molasses of fructose.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110627847A (en) * | 2019-09-17 | 2019-12-31 | 山东百龙创园生物科技股份有限公司 | Preparation method of psicose crystal |
| CN113209670A (en) * | 2021-06-23 | 2021-08-06 | 内蒙古工业大学 | Xylo-oligosaccharide separation and purification system and process in sequential simulated moving bed coupling crystallization process |
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| CN110627847B (en) * | 2019-09-17 | 2023-06-13 | 山东百龙创园生物科技股份有限公司 | Preparation method of psicose crystal |
| CN113209670A (en) * | 2021-06-23 | 2021-08-06 | 内蒙古工业大学 | Xylo-oligosaccharide separation and purification system and process in sequential simulated moving bed coupling crystallization process |
| CN113209670B (en) * | 2021-06-23 | 2022-11-11 | 内蒙古工业大学 | Xylo-oligosaccharide separation and purification system and process in sequential simulated moving bed coupling crystallization process |
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