CN1096272C - Syrup for giving up drug-taking and its preparing process - Google Patents
Syrup for giving up drug-taking and its preparing process Download PDFInfo
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- CN1096272C CN1096272C CN98114499A CN98114499A CN1096272C CN 1096272 C CN1096272 C CN 1096272C CN 98114499 A CN98114499 A CN 98114499A CN 98114499 A CN98114499 A CN 98114499A CN 1096272 C CN1096272 C CN 1096272C
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- 239000006188 syrup Substances 0.000 title claims abstract description 12
- 235000020357 syrup Nutrition 0.000 title claims abstract description 12
- 238000000034 method Methods 0.000 title claims abstract description 4
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- 239000000843 powder Substances 0.000 claims abstract description 11
- 238000002360 preparation method Methods 0.000 claims abstract description 9
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- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 14
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- 238000005516 engineering process Methods 0.000 claims description 10
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- SACAEVOKRBNXPN-UHFFFAOYSA-N n-phenyl-4,5-dihydroimidazol-1-amine Chemical compound C1=NCCN1NC1=CC=CC=C1 SACAEVOKRBNXPN-UHFFFAOYSA-N 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a drug-dropping syrup and its preparation process, wherein the drug-dropping syrup is prepared from ten Chinese medicinal materials of pilose asiabell root, eucommia bark, chestnut shell, licorice root, cyperus tuber and cinnamon bark through the processes of decocting, filtering, concentrating to obtain thick paste, drying and pulverizing the thick paste, mixing with fine powder of amomum fruit and Chinese yam, adding brown sugar and distilled water, filling and making into syrup. The medicine provided by the invention is used for withdrawal syndrome when opium abuse and withdrawal are carried out, and is mainly used for withdrawal treatment of addicts who take opium addiction or inject heroin, dolantine, dihydroetorphine morphine, codeine and the like. Half a month is a treatment course, and the patients with mild symptoms can be abstained and detoxified and recovered. The serious patient can be abstinent and detoxified for rehabilitation in one month, has no side effect of chemical medicine and is not easy to relapse.
Description
The present invention relates to a kind of medicine and preparation technology thereof, particularly a kind of medicine that is used to quit drug abuse and preparation technology thereof.
Narcotics (drugs) is meant that continuous use back easily produces dependency, the medicine of energy addiction, comprising: opiates, cocaines, cannabis, synthetic anesthesia class medicine class, very serious to human health damage, once use a large amount of or frequent application can cause poisonings, deadly.The situation of drug-breaking medicine is at present: all carry out drug addiction treatment to have dependent Western medicine both at home and abroad, this class Western medicine often is difficult for effecting a permanent cure, and the relapse rate height of the poison of reverting to take drugs, and cost height have certain toxic and side effects.Drug addiction treatment for opiate addiction is the problem of all tackling key problems in research in countries in the world always, at present Western medicine methadone (methadone) that adopts and clonidine hydrochloride sheet be after taking, with untoward reaction such as xerostomia, asthenia, dizzy, constipation and postural hypotensions.Become the new developing direction of this research topic and utilize natural plants such as Chinese herbal medicine to quit drug abuse, but do not see prescription listing evident in efficacy yet, many places are in experimental stage.The key of Chinese medicine drug rehabilitation is reasonable proportioning component and pharmaceutical technology thereof, awaits in this respect constantly exploring.
The object of the present invention is to provide a kind ofly according to Chinese medical theory, is the oral syrup type drug-relief medicine that raw material is made with the natural Chinese medicinal herb, this medicine have no chemical drugs toxic and side effects, be difficult for characteristics such as recurrence; Around this medicine a kind of new preparation technology is proposed simultaneously.
The present invention is realized by following technical scheme:
Drug-dropping syrup proposed by the invention is made by following materials of weight proportions and method:
A. press column weight amount percentage ratio and take by weighing raw material:
Foxtail millet shell 19.92%, Radix Codonopsis 15.94%, the Cortex Eucommiae 4.78%, Fructus Amomi 1.59%, Rhizoma Zingiberis Preparatum 3.98%, Pericarpium Citri Reticulatae 1.59%, Poria 3.19%, burnt Fructus Crataegi 4.78%, Radix Glycyrrhizae 1.59%, Rhizoma Cyperi 0.8%, Cortex Cinnamomi 0.8%, Bulbus Fritillariae Cirrhosae 0.8%, sodium benzoate 0.4%, brown sugar 39.84%, standby;
B. decocting: get foxtail millet shell, Radix Codonopsis, the Cortex Eucommiae, Rhizoma Zingiberis Preparatum, Pericarpium Citri Reticulatae, Poria, burnt Fructus Crataegi, Radix Glycyrrhizae, Rhizoma Cyperi, Cortex Cinnamomi, decoct with water secondary, add water for the first time and decocted 3 hours for 10 times, add 8 times of amounts of water for the second time, decocted 2 hours, merge decocting liquid twice, filter, left standstill 12 hours;
C. concentrate: get supernatant concentration to thick paste, the relative density in the time of 30 ℃ is 1.19-1.22;
D. mix: get Fructus Amomi, Bulbus Fritillariae Cirrhosae powder is broken into fine powder, mix thoroughly with above-mentioned thick paste; Get brown sugar and add water, an amount of dissolving is boiled, and filters when hot, and the above-mentioned thick paste mixing of filtrate is put into cold water and added sodium benzoate;
E. finished product: add distilled water to the full dose mixing, fill gets final product.
Raw material consumption wherein is: foxtail millet shell 2500 grams, Radix Codonopsis 2000 grams, the Cortex Eucommiae 600 grams, Fructus Amomi 200 grams, Rhizoma Zingiberis Preparatum 500 grams, Pericarpium Citri Reticulatae 200 grams, Poria 400 grams, burnt Fructus Crataegi 600 grams, Radix Glycyrrhizae 200 grams, Rhizoma Cyperi 100 grams, Cortex Cinnamomi 100 grams, Bulbus Fritillariae Cirrhosae 100 grams, sodium benzoate 50 grams, brown sugar 5000 grams.
The preparation technology of drug-dropping syrup proposed by the invention is:
A. press column weight amount percentage ratio and take by weighing raw material:
Foxtail millet shell 19.92%, Radix Codonopsis 15.94%, the Cortex Eucommiae 4.78%, Fructus Amomi 1.59%, Rhizoma Zingiberis Preparatum 3.98%, Pericarpium Citri Reticulatae 1.59%, Poria 3.19%, burnt Fructus Crataegi 4.78%, Radix Glycyrrhizae 1.59%, Rhizoma Cyperi 0.8%, Cortex Cinnamomi 0.8%, Bulbus Fritillariae Cirrhosae 0.8%, sodium benzoate 0.4%, brown sugar 39.84%, standby;
B. decocting: get foxtail millet shell, Radix Codonopsis, the Cortex Eucommiae, Rhizoma Zingiberis Preparatum, Pericarpium Citri Reticulatae, Poria, burnt Fructus Crataegi, Radix Glycyrrhizae, Rhizoma Cyperi, Cortex Cinnamomi, decoct with water secondary, add water for the first time and decocted 3 hours for 10 times, add 8 times of amounts of water for the second time, decocted 2 hours, merge decocting liquid twice, filter, left standstill 12 hours;
C. concentrate: get supernatant concentration to thick paste, the relative density in the time of 30 ℃ is 1.19-1.22;
D. mix; Get Fructus Amomi, Bulbus Fritillariae Cirrhosae powder is broken into fine powder, mix thoroughly with above-mentioned thick paste; Get brown sugar and add water, an amount of dissolving is boiled, and filters when hot, and the above-mentioned thick paste mixing of filtrate is put into cold water and added sodium benzoate;
E. finished product: add distilled water to the full dose mixing, fill gets final product.
Raw material consumption wherein is: foxtail millet shell 2500 grams, Radix Codonopsis 2000 grams, the Cortex Eucommiae 600 grams, Fructus Amomi 200 grams, Rhizoma Zingiberis Preparatum 500 grams, Pericarpium Citri Reticulatae 200 grams, Poria 400 grams, burnt Fructus Crataegi 600 grams, Radix Glycyrrhizae 200 grams, Rhizoma Cyperi 100 grams, Cortex Cinnamomi 100 grams, Bulbus Fritillariae Cirrhosae 100 grams, sodium benzoate 50 grams, brown sugar 5000 grams.
Advantage of the present invention and good effect are:
1. the set of dispense of Chinese herbal medicine of the present invention is a pharmacological action that makes full use of each component than through repeatedly clinical verification, maximum performance drug effect, effective prescription of also thoroughly removing drug addiction rapidly.
2. preparation technology of the present invention is peculiar at this drug-dropping syrup, and its technology is simply cheap.
3. the present invention provides a kind of effective drug rehabilitation product for junkie and drug intoxication and addict, the withdrawal syndrome during for the disconnected medicine of opiates abuse, and withdrawal is detoxified rapidly.It is mainly used in sucks the opiate addiction suction or injects addict's drug addiction treatments such as heroin, dolantin, dihydroetorphine morphine, codeine.First quarter moon is a course of treatment, but the lighter's first quarter moon withdrawal detoxifcation, rehabilitation.But weight person's withdrawal in January detoxifying recovery, the side effect of no chemical drugs is difficult for recurrence, and Western medicine methadone of no use (methadone), hydrochloric acid are got phenylamino imidazoline sheet, xerostomia, asthenia, untoward reaction such as dizzy, constipation, postural hypotension.
The invention will be further described below in conjunction with embodiment:
The pharmacology of Chinese medicinal ingredients of the present invention is:
1. foxtail millet shell (function with cure mainly): astringing lung-QI and relieving cough, puckery fat antidiarrheal is used for chronic cough, chronic diarrhea, chronic dysentery, all pains of trusted subordinate's muscles and bones, spermatorrhea.
2. Radix Codonopsis (function with cure mainly): invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting is used for weakness of the spleen and stomach, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
3. the Cortex Eucommiae (function with cure mainly): invigorating the liver and kidney, bone and muscle strengthening, antiabortive, be used for lumbago due to renal deficiency, muscles and bones is unable, blood leaking in gestation, frequent fetal movement, vascular hypertension.
4. Fructus Amomi (function with cure mainly): change the reason appetizing, warming spleen and stopping diarrha, it is antiabortive to regulate the flow of vital energy.Be used for turbid damp obstructing in middle-JIAO, the gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, diseases such as tire children uneasiness.
5. Rhizoma Zingiberis Preparatum (function with cure mainly): warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, warming the lung for resolving phlegm.Be applicable to Deficiency and coldness of spleen and stomach, coldness and pain in the epigastrium, yang-energy is on the decline, and faint pulse being about to disappear, lung cold cough, cold physique are carried on the back the cold disease of waiting.
6. Pericarpium Citri Reticulatae (function with cure mainly): promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Be used for the edema oliguria, the phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in the loose stool, irritability, palpitation with fear insomnia.
7. Poria (function with cure mainly): promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Be used for the edema oliguria, the phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in the loose stool, irritability, palpitation with fear insomnia.
8. burnt Fructus Crataegi (function with cure mainly): promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.Be used for meat stagnation, the gastral cavilty distension, dysentery stomachache, the blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain, hyperlipidemia, the effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens, and is used for meat stagnation, and it is not well to rush down disease.
9. Radix Glycyrrhizae (function with cure mainly): invigorating the spleen and replenishing QI, remove thermal detoxification, expelling phlegm for arresting cough is painted anxious pain relieving, transfers as all medicines.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
10. Rhizoma Cyperi (function with cure mainly): promoting QI circulation for relieving depression, reason meridian and relieving pain.Be used for stagnation of QI due to depression of the liver, breast, rib, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type raw meat pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
11. Cortex Cinnamomi (function with cure mainly): it is supporing yang to mend fire, let the fire back to its origin, and dispersing cold for relieving pain is controlled blood and is stimulated the menstrual flow, and is used for sexual impotence, cold womb, chills and pain of the waist and kness is suffered from a deficiency of the kidney and is done to breathe heavily, dizziness due to yang deficiency, the conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, amenorrhea, dysmenorrhea.
12. Bulbus Fritillariae Cirrhosae (function with cure mainly): clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.Be used for lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood.
Illustrate below:
Get raw material: foxtail millet shell 2500 grams, Radix Codonopsis 2000 grams, the Cortex Eucommiae 600 grams, Fructus Amomi 200 grams, Rhizoma Zingiberis Preparatum 500 grams, Pericarpium Citri Reticulatae 200 grams, Poria 400 grams, burnt Fructus Crataegi 600 grams, Radix Glycyrrhizae 200 grams, Rhizoma Cyperi 100 grams, Cortex Cinnamomi 100 grams, Bulbus Fritillariae Cirrhosae 100 grams, sodium benzoate 50 grams, brown sugar 5000 grams.
Get foxtail millet shell, Radix Codonopsis, the Cortex Eucommiae, Rhizoma Zingiberis Preparatum, Pericarpium Citri Reticulatae, Poria, burnt Fructus Crataegi, Radix Glycyrrhizae, Rhizoma Cyperi, Cortex Cinnamomi, decoct with water secondary, add water for the first time and decocted 3 hours for 10 times, add 8 times of amounts of water for the second time, decocted 2 hours, merge decocting liquid twice, filter, left standstill 12 hours.
Get supernatant concentration to thick paste, the relative density in the time of 30 ℃ is 1.19-1.22.Get Fructus Amomi, Bulbus Fritillariae Cirrhosae powder is broken into fine powder, mix thoroughly with above-mentioned thick paste; Get brown sugar and add water, an amount of dissolving is boiled, and filters when hot, and the above-mentioned thick paste mixing of filtrate is put into cold water and added sodium benzoate; Add distilled water to the full dose mixing, fill gets final product.This medicine is reddish brown to bronzing thick liquid, sour in the mouth.
Claims (4)
1. drug-dropping syrup is characterized in that it is made by following materials of weight proportions and method:
A. press column weight amount percentage ratio and take by weighing raw material:
Foxtail millet shell 19.92%, Radix Codonopsis 15.94%, the Cortex Eucommiae 4.78%, Fructus Amomi 1.59%, Rhizoma Zingiberis Preparatum 3.98%, Pericarpium Citri Reticulatae 1.59%, Poria 3.19%, burnt Fructus Crataegi 4.78%, Radix Glycyrrhizae 1.59%, Rhizoma Cyperi 0.8%, Cortex Cinnamomi 0.8%, Bulbus Fritillariae Cirrhosae 0.8%, sodium benzoate 0.4%, brown sugar 39.84%, standby;
B. decocting: get foxtail millet shell, Radix Codonopsis, the Cortex Eucommiae, Rhizoma Zingiberis Preparatum, Pericarpium Citri Reticulatae, Poria, burnt Fructus Crataegi, Radix Glycyrrhizae, Rhizoma Cyperi, Cortex Cinnamomi, decoct with water secondary, add water for the first time and decocted 3 hours for 10 times, add 8 times of amounts of water for the second time, decocted 2 hours, merge decocting liquid twice, filter, left standstill 12 hours;
C. concentrate: get supernatant concentration to thick paste, the relative density in the time of 30 ℃ is 1.19-1.22;
D. mix: get Fructus Amomi, Bulbus Fritillariae Cirrhosae powder becomes fine powder, mix thoroughly with above-mentioned thick paste; Get brown sugar and add water, an amount of dissolving is boiled, and filters when hot, and the above-mentioned thick paste mixing of filtrate is put into cold water and added sodium benzoate;
E. finished product: add distilled water to the full dose mixing, fill gets final product.
2. drug-dropping syrup according to claim 1, raw material consumption wherein is: foxtail millet shell 2500 grams, Radix Codonopsis 2000 grams, the Cortex Eucommiae 600 grams, Fructus Amomi 200 grams, Rhizoma Zingiberis Preparatum 500 grams, Pericarpium Citri Reticulatae 200 grams, Poria 400 grams, burnt Fructus Crataegi 600 grams, Radix Glycyrrhizae 200 grams, Rhizoma Cyperi 100 grams, Cortex Cinnamomi 100 grams, Bulbus Fritillariae Cirrhosae 100 grams, sodium benzoate 50 grams, brown sugar 5000 grams.
3. the preparation technology of drug-dropping syrup is characterized in that:
A. press column weight amount percentage ratio and take by weighing raw material:
Foxtail millet shell 19.92%, Radix Codonopsis 15.94%, the Cortex Eucommiae 4.78%, Fructus Amomi 1.59%, Rhizoma Zingiberis Preparatum 3.98%, Pericarpium Citri Reticulatae 1.59%, Poria 3.19%, burnt Fructus Crataegi 4.78%, Radix Glycyrrhizae 1.59%, Rhizoma Cyperi 0.8%, Cortex Cinnamomi 0.8%, Bulbus Fritillariae Cirrhosae 0.8%, sodium benzoate 0.4%, brown sugar 39.84%, standby;
B. decocting: get foxtail millet shell, Radix Codonopsis, the Cortex Eucommiae, Rhizoma Zingiberis Preparatum, Pericarpium Citri Reticulatae, Poria, burnt Fructus Crataegi, Radix Glycyrrhizae, Rhizoma Cyperi, Cortex Cinnamomi, decoct with water secondary, add water for the first time and decocted 3 hours for 10 times, add 8 times of amounts of water for the second time, decocted 2 hours, merge decocting liquid twice, filter, left standstill 12 hours;
C. concentrate: get supernatant concentration to thick paste, the relative density in the time of 30 ℃ is 1.19-1.22;
D. mix: get Fructus Amomi, Bulbus Fritillariae Cirrhosae powder is broken into fine powder, mix thoroughly with above-mentioned thick paste; Get brown sugar and add water, an amount of dissolving is boiled, and filters when hot, and the above-mentioned thick paste mixing of filtrate is put into cold water and added sodium benzoate;
E. finished product: add distilled water to the full dose mixing, fill gets final product.
4. preparation technology according to claim 3, raw material consumption wherein is: foxtail millet shell 2500 grams, Radix Codonopsis 2000 grams, the Cortex Eucommiae 600 grams, Fructus Amomi 200 grams, Rhizoma Zingiberis Preparatum 500 grams, Pericarpium Citri Reticulatae 200 grams, Poria 400 grams, burnt Fructus Crataegi 600 grams, Radix Glycyrrhizae 200 grams, Rhizoma Cyperi 100 grams, Cortex Cinnamomi 100 grams, Bulbus Fritillariae Cirrhosae 100 grams, sodium benzoate 50 grams, brown sugar 5000 grams.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN98114499A CN1096272C (en) | 1998-11-25 | 1998-11-25 | Syrup for giving up drug-taking and its preparing process |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN98114499A CN1096272C (en) | 1998-11-25 | 1998-11-25 | Syrup for giving up drug-taking and its preparing process |
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CN1254569A CN1254569A (en) | 2000-05-31 |
CN1096272C true CN1096272C (en) | 2002-12-18 |
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CN98114499A Expired - Fee Related CN1096272C (en) | 1998-11-25 | 1998-11-25 | Syrup for giving up drug-taking and its preparing process |
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CN1202843C (en) * | 2002-06-21 | 2005-05-25 | 天大药业(深圳)有限公司 | Drug rehabilitation oral liquid |
CN1305520C (en) * | 2005-07-14 | 2007-03-21 | 邯郸制药有限公司 | Medicinal composition for get rid of opium drug dependence |
CN102940705A (en) * | 2012-12-08 | 2013-02-27 | 吴乃明 | Chinese medicament capable of giving up drug addiction |
Citations (1)
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CN1156041A (en) * | 1996-01-30 | 1997-08-06 | 赵文 | Chinese drug preparation for giving up drug and its producing method |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1156041A (en) * | 1996-01-30 | 1997-08-06 | 赵文 | Chinese drug preparation for giving up drug and its producing method |
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