CN109609368A - The hydration kettle outer circulation that biotransformation method produces acrylamide feeds cooling device - Google Patents
The hydration kettle outer circulation that biotransformation method produces acrylamide feeds cooling device Download PDFInfo
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- CN109609368A CN109609368A CN201811433474.XA CN201811433474A CN109609368A CN 109609368 A CN109609368 A CN 109609368A CN 201811433474 A CN201811433474 A CN 201811433474A CN 109609368 A CN109609368 A CN 109609368A
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- valve
- inlet valve
- heat exchanger
- hydration
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
Abstract
Present invention discloses a kind of hydration kettle outer circulations of biotransformation method production acrylamide to feed cooling device, including being hydrated kettle, ultrafiltration membrane group and discharging pump, the hydration kettle outer circulation charging cooling device that biotransformation method produces acrylamide further includes heat exchanger and injection feeder, the discharge end of heat exchanger is connected to by return valve with hydration kettle, the feed end of heat exchanger is connected to the discharge end of injection feeder, the water inlet end of heat exchanger is communicated with the second inlet valve, the water outlet of heat exchanger is communicated with the second outlet valve, the discharge end of discharging pump passes through casing inlet valve, inner tube inlet valve and outer tube inlet valve are connected to injection feeder, the discharge end of discharging pump is connected to by film inlet valve with ultrafiltration membrane group, injection feeder is communicated with the manual inlet valve of acrylonitrile, the manual inlet valve of acrylonitrile is parallel with acrylonitrile magnetic feeder valve；The production cost that the present invention can be improved acrylamide product quality, reduce subsequent refining step.
Description
Technical field
The present invention relates to acrylamide production engineering device technique fields, and in particular to a kind of biotransformation method production acryloyl
The hydration kettle outer circulation of amine feeds cooling device.
Background technique
Currently, the manufacturer of domestic biotransformation method production acrylamide is all made of intermittent reaction, batch preparation, produce
Quality is not easy to stablize.The reaction condition control quality of hydration reaction kettle is directly related to biotransformation method production acrylamide
Product quality and production cost, wherein hydration reaction temperature control is the most important thing, and hydration reaction temperature determines hydration reaction
Speed and reaction time are related to the impurity such as hydration reaction by-product propylene content, the conductivity of aqua liquid, aqua liquid Pf and contain
Amount, acrylamide AM product quality, etc..25m at present3Be hydrated kettle it is cooling be typically all stream plus acrylonitrile reactor in hydration kettle,
Cooled down using coil pipe, but the period most fierce in hydration reaction, cool down by reaction kettle inner coil pipe, is often unable to control
Reaction temperature will cause biocatalyst enzyme activity to reduce, hydration once reaction temperature this period is more than optimum temperature range
The phenomenon that liquid impurity increases, conductivity increases, to will cause subsequent purification, the production cost increases, and product quality reduces, and
Biological enzyme eliminates replacement after generally using 5~7 batches, right after each batch reaction temperature increases in the 1st~5 or 7 batches
The enzymatic performance of latter batch will cause irreversible influence.
As shown in Figure 1, it is common hydration kettle discharging mode group on the market at present comprising hydration kettle a, ultrafiltration membrane group b,
Cooling water inlet valve a1, cooling water outlet valve a2, acrylonitrile inlet valve a3, outlet valve a4, bottom valve a5, acrylamide filtrate valve
B1, backwash water valve b2, the wash water valve b3, film inlet valve b4 and discharging pump c.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of hydration kettle outer circulation of biotransformation method production acrylamide
Feed cooling device, can be improved hydration reaction speed, shorten the reaction time, reduce hydration reaction by-product acrylic acid contain
Amount, reduces subsequent refining step at the product quality for the conductivity for reducing aqua liquid, reducing aqua liquid impurity, improving acrylamide
Production cost.
The hydration kettle outer circulation charging cooling device of biotransformation method production acrylamide of the invention, including hydration kettle,
Ultrafiltration membrane group and discharging pump are hydrated the coil pipe inside kettle and are communicated with the first inlet valve and the first outlet valve, and hydration kettle is communicated with third
Alkene nitrile inlet valve, ultrafiltration membrane group are connected to by outlet valve with hydration kettle, and ultrafiltration membrane group is communicated with acrylamide filtrate valve, backwash water
Valve and the wash water valve, the one end of backwash water valve far from ultrafiltration membrane group are connected to the wash water valve far from one end of ultrafiltration membrane group, discharging
The feed end of pump is connected to by bottom valve with hydration kettle, and biotransformation method produces the cooling dress of hydration kettle outer circulation charging of acrylamide
Setting further includes heat exchanger and injection feeder, and the discharge end of heat exchanger is connected to by return valve with hydration kettle, the charging of heat exchanger
End is connected to the discharge end of injection feeder, and the water inlet end of heat exchanger is communicated with the second inlet valve, the water outlet connection of heat exchanger
There is the second outlet valve, the discharge end of discharging pump passes through casing inlet valve, inner tube inlet valve and outer tube inlet valve and injection feeder
The discharge end of connection, discharging pump is connected to by film inlet valve with ultrafiltration membrane group, and injection feeder is communicated with acrylonitrile and feeds manually
Valve, the manual inlet valve of acrylonitrile are parallel with acrylonitrile magnetic feeder valve.
The hydration kettle outer circulation of biotransformation method production acrylamide of the invention feeds cooling device, wherein biology turns
The hydration kettle outer circulation charging cooling device that change method produces acrylamide further includes temperature sensor and solenoid valve, temperature sensor
It being mounted on the pipeline between return valve and heat exchanger, solenoid valve is mounted on the pipeline between heat exchanger and the second inlet valve,
Solenoid valve is electrically connected with temperature sensor.
The structure by the present invention in that the outer circulation charging constituted with heat exchanger and injection feeder cools, through overspray
Feeder, acrylonitrile and reaction solution containing biocatalyst reach moment charging, mixing, reaction on injection feeder head, can be with
By adjusting the opening size of acrylonitrile magnetic feeder valve and inner tube inlet valve, outer tube inlet valve, it is fast effectively to control reaction speed
Slow and reaction heat size, mixed reaction solution by the refrigerant of heat exchanger synchronous cooling down in time, reach side border ring synchronize it is cold
But purpose；Kettle internal cooling coil pipe is hydrated as cooling supplement, in the case where temperature-controllable, is hydrated the acrylonitrile charging of kettle
Valve can also moderately open charging, not only can be shortened the reaction time but also can control hydration reaction temperature, and achieved effective control hydration
Reaction temperature plays the catalytic performance of biological enzyme in the purpose of optimum temperature range to greatest extent, can be improved hydration reaction speed
Degree, the conductivity shorten the reaction time, reduce hydration reaction by-product acrylic acid content, reducing aqua liquid, reduction aqua liquid are miscellaneous
Matter, the production cost for improving acrylamide product quality, reducing subsequent refining step.
Detailed description of the invention
The drawings described herein are used to provide a further understanding of the present application, constitutes part of this application, this Shen
Illustrative embodiments and their description please are not constituted an undue limitation on the present application for explaining the application.In the accompanying drawings:
Fig. 1 is the structural schematic diagram for commonly using hydration kettle discharging mode group in the prior art；
Fig. 2 is structural schematic diagram of the invention.
Specific embodiment
Multiple embodiments of the invention will be disclosed with schema below, as clearly stated, the details in many practices
It will be explained in the following description.It should be appreciated, however, that the details in these practices is not applied to limit the present invention.Also
It is to say, in some embodiments of the invention, the details in these practices is non-essential.In addition, for the sake of simplifying schema,
Some known usual structures and component will be painted it in the drawings in simply illustrative mode.
In addition, the description for being such as related to " first ", " second " in the present invention is used for description purposes only, not especially censure
The meaning of order or cis-position, also non-to limit the present invention, the component described just for the sake of difference with same technique term
Or operation, it is not understood to indicate or imply its relative importance or implicitly indicates the number of indicated technical characteristic
Amount." first " is defined as a result, the feature of " second " can explicitly or implicitly include at least one of the features.In addition, each
Technical solution between a embodiment can be combined with each other, but must can be implemented as base with those of ordinary skill in the art
Plinth will be understood that the combination of this technical solution is not present when conflicting or cannot achieve when occurs in the combination of technical solution,
Also not the present invention claims protection scope within.
The hydration kettle outer circulation charging cooling device of biotransformation method production acrylamide of the invention, including hydration kettle 1,
Ultrafiltration membrane group 2 and discharging pump 3 are hydrated the coil pipe inside kettle 1 and are communicated with the first inlet valve 11 and the first outlet valve 12, be hydrated kettle 1
It is communicated with acrylonitrile inlet valve 13, ultrafiltration membrane group 2 is connected to by outlet valve 14 with hydration kettle 1, and ultrafiltration membrane group 2 is communicated with acryloyl
Amine filtrate valve 21, backwash water valve 22 and the wash water valve 23, backwash water valve 22 one end and the wash water valve 23 far from ultrafiltration membrane group 2 are remote
The feed end of one end connection from ultrafiltration membrane group 2, discharging pump 3 is connected to by bottom valve 15 with hydration kettle 1, biotransformation method production third
The hydration kettle outer circulation charging cooling device of acrylamide further includes heat exchanger 4 and injection feeder 5, and the discharge end of heat exchanger 4 is logical
Cross return valve 41 with hydration kettle 1 be connected to, the feed end of heat exchanger 4 is connected to the discharge end of injection feeder 5, heat exchanger 4 into
Water end (W.E.) is communicated with the second inlet valve 42, and the water outlet of heat exchanger 4 is communicated with the second outlet valve 43, and the discharge end of discharging pump 3 passes through
Casing inlet valve 31, inner tube inlet valve 32 and outer tube inlet valve 33 are connected to injection feeder 5, and the discharge end of discharging pump 3 passes through
Film inlet valve 34 is connected to ultrafiltration membrane group 2, and injection feeder 5 is communicated with the manual inlet valve 51 of acrylonitrile, and acrylonitrile is fed manually
Valve 51 is parallel with acrylonitrile magnetic feeder valve 52.
The hydration kettle outer circulation charging cooling device that biotransformation method produces acrylamide further includes temperature sensor 6 and electricity
Magnet valve 7, temperature sensor 6 are mounted on the pipeline between return valve 41 and heat exchanger 4, and solenoid valve 7 is mounted on heat exchanger 4 and
On pipeline between two inlet valves 42, solenoid valve 7 is electrically connected with temperature sensor 6.
In using the present invention: after hydration reaction starts, can choose and close film inlet valve 34, open the inner tube of outer circulation
Inlet valve 32, outer tube inlet valve 33, bottom valve 15, return valve 41, the second inlet valve 42, the second outlet valve 43, unlatching discharging pump (follow
Ring pump) 3, make aqua liquid in outer recycle feed cooling pipe circulating reflux, then appropriateness opens acrylonitrile magnetic feeder valve 52, leads to
For 6 feedback temperature signal of excess temperature sensor to solenoid valve 7, solenoid valve 7 automatically adjusts aperture, realizes effective control of temperature, such as
The control of the temperature of fruit outer circulation pipeline and hydration reaction kettle is good, can moderately open the first inlet valve 11,12 and of the first outlet valve
Charging acrylonitrile is sent into acrylonitrile inlet valve 13, Xiang Shuihe kettle inside, and realization outer circulation injection acrylonitrile is fed and hydration kettle top
Portion's acrylonitrile feeds while carrying out.In the hydration reaction later period, outer circulation injection acrylonitrile charging and hydration kettle top may gradually reduce
Acrylonitrile charging in portion's closes acrylonitrile magnetic feeder valve 52 and acrylonitrile inlet valve 13 when the reaction is finished, and appropriateness opens casing
Inlet valve 31 replaces residual propylene nitrile in the casing of injection feeder 5.When hydration kettle acrylamide concentration and acrylonitrile residual symbol
Discharging standard is closed, then in addition to maintenance opens bottom valve 15, discharging pump (circulating pump) 3, opens film inlet valve 34, return valve
41, acrylamide filtrate valve 21, closes casing inlet valve 31, inner tube inlet valve 32, outer tube inlet valve 33, and selection is enabled and discharged back
Road and the discharging of ultrafiltration membrane group start next group and feed intake until terminating.
The upper only embodiments of the present invention, are not intended to restrict the invention.For those skilled in the art
For, the invention may be variously modified and varied.All any modifications made in spirit and principles of the present invention are equal
Replacement, improvement etc., should all be included within scope of the presently claimed invention.
Claims (2)
1. a kind of hydration kettle outer circulation of biotransformation method production acrylamide feeds cooling device, including hydration kettle (1), ultrafiltration
Film group (2) and discharging pump (3), the internal coil pipe of hydration kettle (1) are communicated with the first inlet valve (11) and the first outlet valve
(12), the hydration kettle (1) is communicated with acrylonitrile inlet valve (13), and the ultrafiltration membrane group (2) passes through outlet valve (14) and hydration
Kettle (1) connection, the ultrafiltration membrane group (2) are communicated with acrylamide filtrate valve (21), backwash water valve (22) and the wash water valve (23),
The one end of the backwash water valve (22) far from ultrafiltration membrane group (2) is connected to the wash water valve (23) far from the one end of ultrafiltration membrane group (2),
The feed end of the discharging pump (3) is connected to by bottom valve (15) with hydration kettle (1), it is characterised in that: the biotransformation method is raw
The hydration kettle outer circulation charging cooling device for producing acrylamide further includes heat exchanger (4) and injection feeder (5), the heat exchanger
(4) discharge end is connected to by return valve (41) with hydration kettle (1), the feed end of the heat exchanger (4) and injection feeder (5)
Discharge end connection, the water inlet end of the heat exchanger (4) is communicated with the second inlet valve (42), the water outlet of the heat exchanger (4)
Be communicated with the second outlet valve (43), the discharge end of the discharging pump (3) by casing inlet valve (31), inner tube inlet valve (32) and
Outer tube inlet valve (33) is connected to injection feeder (5), and the discharge end of the discharging pump (3) passes through film inlet valve (34) and ultrafiltration
Film group (2) connection, the injection feeder (5) are communicated with the manual inlet valve of acrylonitrile (51), the manual inlet valve of acrylonitrile
(51) it is parallel with acrylonitrile magnetic feeder valve (52).
2. the hydration kettle outer circulation of biotransformation method production acrylamide according to claim 1 feeds cooling device,
It is characterized in that, the hydration kettle outer circulation charging cooling device of the biotransformation method production acrylamide further includes temperature sensor
(6) and solenoid valve (7), the temperature sensor (6) is mounted on the pipeline between return valve (41) and heat exchanger (4), described
Solenoid valve (7) is mounted on the pipeline between heat exchanger (4) and the second inlet valve (42), the solenoid valve (7) and temperature sensing
Device (6) electrical connection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811433474.XA CN109609368A (en) | 2018-11-28 | 2018-11-28 | The hydration kettle outer circulation that biotransformation method produces acrylamide feeds cooling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811433474.XA CN109609368A (en) | 2018-11-28 | 2018-11-28 | The hydration kettle outer circulation that biotransformation method produces acrylamide feeds cooling device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109609368A true CN109609368A (en) | 2019-04-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201811433474.XA Pending CN109609368A (en) | 2018-11-28 | 2018-11-28 | The hydration kettle outer circulation that biotransformation method produces acrylamide feeds cooling device |
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Citations (11)
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| CN206204187U (en) * | 2016-11-28 | 2017-05-31 | 江苏斯尔邦石化有限公司 | A kind of MMA productions cooling device of hybrid reaction system |
| CN207552317U (en) * | 2017-11-08 | 2018-06-29 | 南通博亿化工有限公司 | A kind of acrylamide produces purifier apparatus |
| CN208472052U (en) * | 2018-05-09 | 2019-02-05 | 山东香驰健源生物科技有限公司 | Starch milk and liquefier comprehensive utilization system for heat energy in fructose production process |
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2018
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Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040175809A1 (en) * | 2001-04-26 | 2004-09-09 | Olaf Peterson | Method for producing an aqueous acrylamide solution with a biocatalyst |
| CN101394921A (en) * | 2006-03-07 | 2009-03-25 | 托塔尔石油化学产品研究弗吕公司 | Method and system for determining catalyst activity |
| CN102015086A (en) * | 2008-04-30 | 2011-04-13 | 通用电气公司 | Methods and systems for feed injector multi-cooling channel |
| CN101684064A (en) * | 2009-07-21 | 2010-03-31 | 厦门中坤化学有限公司 | Environment-friendly process for producing dihydromyrcenol by using dihydromyrcene hydration reaction |
| CN202808773U (en) * | 2012-07-20 | 2013-03-20 | 江苏南天农科化工有限公司 | Series connection device of multiple stages of acrylamide reaction kettles |
| CN103361268A (en) * | 2013-08-06 | 2013-10-23 | 宁波先安化工有限公司 | A continuous catalytic hydration preparation system and a preparation method for acrylamide |
| CN203530325U (en) * | 2013-08-06 | 2014-04-09 | 宁波先安化工有限公司 | Acrylamide continuous catalytic hydration preparation system |
| CN106367454A (en) * | 2016-08-25 | 2017-02-01 | 山东省鲁洲食品集团有限公司 | Method of continuously jetting liquefaction for starch at high concentration |
| CN206204187U (en) * | 2016-11-28 | 2017-05-31 | 江苏斯尔邦石化有限公司 | A kind of MMA productions cooling device of hybrid reaction system |
| CN207552317U (en) * | 2017-11-08 | 2018-06-29 | 南通博亿化工有限公司 | A kind of acrylamide produces purifier apparatus |
| CN208472052U (en) * | 2018-05-09 | 2019-02-05 | 山东香驰健源生物科技有限公司 | Starch milk and liquefier comprehensive utilization system for heat energy in fructose production process |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190412 |
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| RJ01 | Rejection of invention patent application after publication |