CN109596670A - A kind of electric/magnetic field environment comprehensive generating system - Google Patents

A kind of electric/magnetic field environment comprehensive generating system Download PDF

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CN109596670A
CN109596670A CN201811499405.9A CN201811499405A CN109596670A CN 109596670 A CN109596670 A CN 109596670A CN 201811499405 A CN201811499405 A CN 201811499405A CN 109596670 A CN109596670 A CN 109596670A
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gradient
coil
plate
magnetic
electric
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CN109596670B (en
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李光辉
奚鹏程
李菠
董媛瑞
何际平
张西峰
刘杰
郭江黔
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Beijing Institute of Technology BIT
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Beijing Institute of Technology BIT
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05FSYSTEMS FOR REGULATING ELECTRIC OR MAGNETIC VARIABLES
    • G05F1/00Automatic systems in which deviations of an electric quantity from one or more predetermined values are detected at the output of the system and fed back to a device within the system to restore the detected quantity to its predetermined value or values, i.e. retroactive systems
    • G05F1/10Regulating voltage or current

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Abstract

The invention discloses a kind of electric/magnetic field environment comprehensive generating systems, including host computer, gradient magnetic generating device and electromagnetic field device, host computer is connect with gradient magnetic generating device by data line, and gradient magnetic generating device is connect with electromagnetic field device by power supply line;Electromagnetic field device includes being set in parallel in the first plate gradient coil of parallel interval setting and the second plate gradient coil and the multiple planar excitation electrical field coils being set in distance between the first plate gradient coil and the second plate gradient coil, each planar excitation electrical field coil with the first plate gradient coil;When work, each planar excitation electrical field coil surface between the first plate gradient coil and the second plate gradient coil forms the magnetic field of distribution gradient, and the planar excitation electrical field coil for being located at different location generates different electric fields, two kinds of physical field environment of electric and magnetic fields are realized, can be used for carrying out biological effect and biological response Mechanism Study under multiple physical field environment.

Description

A kind of electric/magnetic field environment comprehensive generating system
Technical field
The present invention relates to electromagnetic application and bioengineering and engineering in medicine art fields, and in particular to a kind of electric/magnetic field environment Comprehensive generating system, it can be achieved that screened to physical field environmental condition to the big flux of multidimensional when plane and 3D are cultivated, It can be used for the device/system of biological effect and biological response Mechanism Study under multiple physical field environment.
Background technique
Electrotechnics development promotes the increasing fast of electrical equipment in life production, and relevant electromagnetic field environment is to people The influence of body and living environment is also increasingly by social concerns and attention.Universal result of study shows the heat of electromagnetic field of high frequency Effect has certain nocuity to human body, and daily life is 50Hz with electric frequency, and Extremely low frequency electromagnetic field refers generally to 300Hz or less The electromagnetic wave of frequency, with many electromagnetic environments that daily life is closely related belong to Extremely low frequency electromagnetic field environmental field it It is interior.For example, UHV transmission, rail traffic, the influence to human health such as magnetic levitation technology is by social common concern, even Affect the planning and decision of some Large Infrastructure Projects construction.
Although for many years, having carried out a large amount of research to the physiological effect of low frequency electromagnetic environment, not yet shape so far At unification, specific research conclusion.Its reason is experimental facilities and research method between each laboratory and researcher The inconsistent difference for causing experimental result.With in recent years including electric field, magnetic field, the multiple physical means such as far infrared start to be situated between Enter rehabilitation medical and biomedical engineering field, under a variety of physics field actions biological effect and biofacies answer grinding for mechanism Study carefully and explores new effective treatment method, specification related fields product and market to nocuity physical environment is evaded, it is correct to formulate Effective therapeutic scheme provides the guiding theory of science.Using a kind of standard, general physical field generating device can grind correlation The development for studying carefully work will be played the role of greatly facilitating.
There is not even relevant device that can apply electric field/magnetic field in the same space in current open report data comprehensive , for biological effect under multiple physical field environment and biological response Mechanism Study comprehensive electric/magnetic field environment generating system.In State patent document CN 101324552B discloses the design method and Chinese patent literature of a kind of magnetic field biology effect experiment instrument CN 106886001A discloses a kind of controllable magnetic field generating device for biological study, and coil system uses Hai Muhuo Hereby coil generates stationary magnetic field, and disturbance of magnetic field, the existing research to magnetic field biology effect are realized by current impulse design Similar device is mostly used, Magnetic Field Design target is that can form stable uniform magnetic field in the inner space of magnetic field, therefore be placed in such Biological sample in the device space can only receive the magnetic field environment of uniform level, i.e., each laboratory sample in stable magnetic field region A kind of intensity magnetic field environmental treatment can only be done.Quantity of sample handling is small, and in addition such system can only apply magnetic field environment, cannot be to life Object sample applies electric field environment, cannot do the analysis of synthetic physical field environment influence.
Summary of the invention
Therefore, object of the present invention is to solve under electric field, two kinds of magnetic field physical field environment, carry out raw under multiple physical field environment Object effect and biological response Mechanism Study realize the magnetic field environment and electric field environment of a variety of levels in stable magnetic field region, For this purpose, the present invention provides a kind of electric/magnetic field environment comprehensive generating systems.
Used technical solution is as follows:
On the one hand, the present invention provides a kind of electric/magnetic field environment comprehensive generating system, the system comprises host computers, ladder Degree field generator for magnetic and electromagnetic field device, the host computer are connect with the gradient magnetic generating device by data line, institute It states gradient magnetic generating device and is connect with the electromagnetic field device by power supply line, for providing stabilization for the electromagnetic field device Magnetic field, the host computer are that the electromagnetic field device carries out current impulse size and electric current by the gradient magnetic generating device The adjusting of pulse train;The electromagnetic field device includes the first plate gradient coil and the second plate ladder in parallel interval setting Spend coil and the multiple planes being set in distance between the first plate gradient coil and the second plate gradient coil Excitation electrical field coil, each planar excitation electrical field coil are set in parallel with the first plate gradient coil;By upper When position machine controls gradient magnetic generating device work, in the first plate gradient coil and the second plate gradient line Each planar excitation electrical field coil surface between circle forms the magnetic field of distribution gradient, and in each planar excitation electric field Different electric fields is generated in coil.
Further, the gradient magnetic generating device includes electromagnetic shielding rack and is located in the electromagnetic shielding rack Digital analog converter, gradient controller, gradient power, gradient amplifier, high pressure caching capacitor and analog-digital converter, it is described upper Machine is connect by data line with the digital analog converter, and the digital analog converter and the gradient controller are connected by signal wire It connects, the gradient controller caches capacitance connection with the gradient amplifier and high pressure respectively by signal wire;The gradient Power supply is electrically connected by power supply line and the gradient amplifier, and the gradient amplifier is exported according to the gradient controller Waveform amplifies the electric current of the gradient power output, the gradient amplifier and high pressure caching capacitor and first plate Gradient coil and the second plate gradient coil are electrically connected;Gradient controller described in the PC control exports multiple waveforms Signal is controlled, the high pressure caching capacitor is that the electromagnetic field device carries out high pressure according to the control instruction of the gradient controller Power supply.
Further, the gradient magnetic generating device further includes analog-digital converter, by signal wire respectively with it is described Electromagnetic field device, gradient controller connection, the analog-digital converter acquire the first plate gradient coil and second flat in real time Current signal in plate gradient coil, and current signal collected is fed back into the gradient controller.
It is further preferred that being additionally provided with heat exchanger tube inside the first plate gradient coil and the second plate gradient coil Road, the heat exchanging pipe are connect with external water cooling plant, for being the first plate gradient coil and the second plate gradient Coil cools down.
The waveform control signal of the gradient controller output is that continuous wave controls signal or interruption waveform control signal, It includes one of sine wave, triangular wave, trapezoidal wave and square wave, and output waveform frequency is 0~155Hz.
The planar excitation electrical field coil is Archimedes's shape planar coil.
The surface of the planar excitation electrical field coil is covered with Signa Gel coating, and is equipped at least one in its perimeter A open point electrode point I, position is equipped with an open point electrode point II, the opening point electrode point I, open point therebetween Electrode points II and the Signa Gel apply interlayer and form closed circuit.
Preferably, the first plate gradient coil and the second plate gradient coil are located below in setting up and down The second plate gradient coil be equipped with a bracket, each planar excitation electrical field coil is set to described in parallel interval On bracket.
The bracket includes at least three pillars, and the planar excitation electrical field coil is equipped with and the pillar installation site Corresponding through-hole, the planar excitation electrical field coil are placed on each pillar by the through-hole, and adjacent two is described flat The regulation pipe for adjusting the two planar excitation electrical field coil spacing is equipped on pillar between the excitation electrical field coil of face.
Preferably, the regulation pipe is acrylic pipe.
The electromagnetic field device further includes covering in outside the first plate gradient coil and the second plate gradient coil Without magnetic acrylic transparent sealing outer cover.
Technical solution of the present invention has the advantages that
A. the present invention is provided with the first plate gradient coil and the second plate gradient coil in electromagnetic field device, and the The multilayer planar excitation electrical field coil that can produce electric field is provided between one plate gradient coil and the second plate gradient coil, The design for carrying out current impulse size and current pulse sequence to gradient magnetic generating device by host computer, in two plate gradients It is formd between coil by the extremely linear gradient magnetic field environment of the medium position distribution gradient of the two spacing, and position on the inside of plate Different electric fields is generated in the planar excitation electrical field coil of different location, realizes two kinds of physical field environment of electric and magnetic fields, it can For carrying out biological effect and biological response Mechanism Study under multiple physical field environment.
B. the present invention can generate stabilizing magnetic field on the different level between two plate gradient coils, can also pass through Gradient magnetic field pulses are applied to different level, induction field is generated on planar excitation electrical field coil, is applied to culture, It can be realized in same culture plane in plane 2D and 3D culture, big flux is carried out to electric field/physical field environmental condition Ground screening.Using high bio-compatibility natural polymers Signa Gel as biology 3D material and external structure organoid structure Skeleton realizes the controllable building of multidimensional ordered structure in conjunction with biological 3D printing technique, realizes and carries out mould to cell and tissue model It is quasi-, influence of the electric and magnetic fields synthetic physical field environment to physiological effect is explored, and be used for therapeutic electric field/magnetic field stimulation parameter Screening.
C. the planar excitation electrical field coil in the present invention uses Archimedes's coil, the gradient magnetic phase is being maintained, by applying The design of loading current sequence can cause gradient fields environmental perturbation, and the disturbance in magnetic field will cause Archimedes in coil space The variation of coil flux amount, change of flux can further induce Archimedes's coil and generate excitation electrical field, and the present invention can pass through The design for changing Archimedes's coil magnetic flux line circle winding density changes coil flux area, even if in same gradient plane, Electromagnetic disturbance degree is consistent, however the difference of the magnetic flux area due to coil, each coil induce different excitation electrical fields.It is logical Adjustment magnetic field pulse sequence size, frequency are crossed, waveform emergence pattern stimulates emergence pattern to test excitation electrical field, and excitation electrical field is big It is small, frequency, duration.The characteristics of system has high throughput, flexibly adjustable, multi-mode is, it can be achieved that a variety of magnetic in the same space Field, electromagnetic environment are simulated, and biological effect and biological response mechanism under the comprehensive field environment of electric and magnetic fields complexity are suitable for Carry out the research of exploration.
D. the present invention is the comprehensive field generating device of a set of electric field/magnetic field, and apparatus structure design is succinct, flexible setting for parameters, It can be used for the Large-scale Screening of effective biological effect physical field environment, while the device can be used as a set of biomedicine that is used for and lead The standardized equipment of domain research and teaching can study each laboratory with effective solution current electric field/magnetic field biology effect and grind Study carefully the big problem of means disunity, result difference.
Detailed description of the invention
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art Embodiment or attached drawing needed to be used in the description of the prior art be briefly described, it should be apparent that, it is described below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is electric/magnetic field environment comprehensive generating system overall structure diagram provided by the present invention;
Fig. 2-1 is electromagnetic field device side view;
Fig. 2-2 is top view shown in Fig. 2-1;
Fig. 3-1 is supporting structure installation diagram in Fig. 2-1;
Fig. 3-2 is supporting structure perspective view in Fig. 3-1;
Fig. 4-1 is the assembling side elevation of plate gradient coil;
Fig. 4-2 is the top view of Fig. 4-1;
Fig. 4-3 is the perspective view of Fig. 4-1;
Fig. 5 show the planar excitation electric field Archimedes that cell tissue two-dimensional culture system is used in the embodiment of the present invention Coil design master drawing
Fig. 6 show the planar excitation electric field plan view that cell tissue three dimensional culture system is used in the embodiment of the present invention.
In figure:
1- host computer
2- gradient magnetic generating device
21- electromagnetic shielding rack, 22- digital analog converter, 23- gradient controller, 24- gradient power
25- gradient amplifier, 26- high pressure cache capacitor, 27- analog-digital converter
3- electromagnetic field device
31- the first plate gradient coil, 32- the second plate gradient coil
33- planar excitation electrical field coil, the open point electrode point II of 331- open point electrode point I, 332-
34- transparent sealing outer cover
4- data line;5- power supply line;6- signal wire;7- heat exchanging pipe;8- water cooling plant
9- bracket
91- pillar, 92- regulation pipe, 93- frame
10- Signa Gel coating.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with attached drawing.Obviously, described implementation Example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill Personnel's every other embodiment obtained without making creative work, shall fall within the protection scope of the present invention.
As shown in Figure 1, Figure 2 shown in-1 and Fig. 2-2, the present invention provides a kind of electric/magnetic field environment comprehensive generating system, including it is upper Position machine 1, gradient magnetic generating device 2 and electromagnetic field device 3, host computer 1 are connected with gradient magnetic generating device 2 by data line 4 It connects, gradient magnetic generating device 2 is connect with electromagnetic field device 3 by power supply line 5, for providing stable magnetic for electromagnetic field device 3 , host computer 1 is that electromagnetic field device 3 carries out current impulse size and current pulse sequence by gradient magnetic generating device 2 It adjusts;Electromagnetic field device 3 include in parallel interval setting the first plate gradient coil 31 and the second plate gradient coil 32 and The multiple planar excitation electric fields being set in distance between the first plate gradient coil 31 and the second plate gradient coil 32 Coil 33, each planar excitation electrical field coil 33 are set in parallel with the first plate gradient coil 31;Gradient magnetic generating device 2 Each planar excitation electrical field coil 33 when work, between the first plate gradient coil 31 and the second plate gradient coil 32 The magnetic field of surface formation distribution gradient.Host computer 1 therein can carry out 2 current impulse size of gradient magnetic generating device and Current pulse sequence design, while the communication realized between each system electronics can be connect with gradient magnetic generating device 2, it is real Existing gradient magnetic generating device 2 is stablized.
Here gradient magnetic generating device 2 includes electromagnetic shielding rack 21 and the digital-to-analogue in electromagnetic shielding rack 21 Converter 22, gradient controller 23, gradient power 24, gradient amplifier 25, high pressure caching capacitor 26 and analog-digital converter 27, on Position machine 1 is connect by data line 4 with digital analog converter 22, and digital analog converter 22 is connect with gradient controller 23 by signal wire 6, Gradient controller 23 caches capacitor 26 with gradient amplifier 25, high pressure respectively by signal wire 6 and analog-digital converter 27 is connect, mould Number converter 27 is connect with electromagnetic field device 3 by signal wire 6;Gradient power 24 passes through 25 electricity of power supply line 5 and gradient amplifier Property connection, the electric current for the waveform amplification output of gradient power 24 that gradient amplifier 25 export according to gradient controller 23, gradient puts Big device 25 and high pressure caching capacitor 26 and the first plate gradient coil 31 and the second plate gradient coil 32 are electrically connected;Host computer 1 control gradient controller 23 exports the control signal of multiple waveforms, and high pressure caches capacitor 26 according to the control of gradient controller 23 Instruction is that electromagnetic field device 3 carries out high voltage supply.
Here gradient controller 23 is 1 current sequence information actuator of host computer, is amplified by signal wire 6 and gradient Device 25 is connected, and gradient controller 23 can export the control signal of multiple waveforms, including sine wave, triangular wave, trapezoidal wave, square wave Equal waveforms, the frequency range of output waveform are 0-155Hz, frequency departure 5%;It is defeated that waveform output can both make continuous wave Out, waveform output gap also can be set, adjustable, the step of adjusting between interval time range 0~60 second between output waveform Width is 0.5s.Output is provided with base band option simultaneously.Gradient controller 23 is connected by signal wire 6 with gradient amplifier 7, ladder The electric current that the waveform amplification gradient power 24 that degree amplifier 25 is exported according to gradient controller 23 exports, gives the first plate gradient line Circle 31 and the second plate gradient coil 32 are powered.High pressure cache capacitor 26 by power supply line 5 and the first plate gradient coil 31 and Second plate gradient coil 32 is connected, and it is electromagnetic field device 3 that high pressure, which caches capacitor 26 according to the control instruction of gradient controller 23, Pass through high voltage supply.Analog-digital converter 27 is connected by signal wire 6 with gradient controller 23 and electromagnetic field device 3, analog-to-digital conversion Device 27 acquires the current signal of the first plate gradient coil 31 and the second plate gradient coil 32 in real time, feeds back to gradient controller 23, realize accurate control of the gradient controller 23 to electromagnetic field device 3.Cell and tissue structrue room and planar excitation electrical field coil 33 Positioned at the inside of the first plate gradient coil 31 and the second plate gradient coil 32, cell and tissue structrue room provides cell culture Environment, planar excitation electrical field coil 33 generate stimulation field.
In order to maintain the stabilization of entire electromagnetic field environment, as shown in Fig. 1 and Fig. 4-1, Fig. 4-2 and Fig. 4-3.The present invention is two A plate gradient coil interior parallel is placed with heat exchanging pipe 7, and heat exchanging pipe 7 and external water-cooling device 8 collectively form coil water Cooling system realizes the water-cooling system temperature-controllable of coil, controls precision in ± 1 degree, water-cooling system can be to avoid because being powered Journey coil, while can be consistent with hold-in winding resistance performance process temperature because of the excessively high damage of heat production.
As shown in Figure 5 and Figure 6, currently preferred planar excitation electrical field coil 33 uses Archimedes's shape planar coil, It is covered with Signa Gel coating 10 on the surface of planar excitation electrical field coil 33, and be uniformly provided with four in its perimeter to have The opening point electrode point I331 of equal high potentials, position setting has the opening point electrode point II332 of low potential therebetween, open Closed circuit is formed between point electrode point I331, open point electrode point II332 and Signa Gel coating 10.Biological culture object is in conduction It is cultivated on gel layer, gel is used to electric field being strapped in gel layer.Four are provided in the outside of planar excitation electrical field coil in Fig. 5 A open point is waits high voltages, and the open point in centre is low potential point, and electric current passes through conductive gel layer and flows to center by surrounding, Uniform electric field environment is formed inside gel.In two planar excitation coils in Fig. 6, magnetic flux in two planar excitation coils Change direction is consistent, and current direction is consistent, all for clockwise or counterclockwise, so that the opening point electrode of one of thiol Point II forms high voltage, and the opening point electrode point II of another thiol forms low potential point, and electric current passes through among two coils Signa Gel forms closed circuit, applies electrical field stimulation to the culture in gel.
On same H plane, since Archimedes's coil magnetic flux size is different, the inductance potential of acquisition it is big Gradient electric field design may be implemented in small difference.Culture is placed on planar excitation electrical field coil 33 and is cultivated, it can be by upper Machine 1 changes magnetic field pulse and size and emergence pattern occurs, and influences excitation electrical field emergence pattern, realizes and carries out difference to culture The electro photoluminescence of mode.Therefore the first plate gradient coil 31 in the present invention and the second plate gradient coil 32 and Archimedes Planar excitation electrical field coil 33 collectively constitutes complicated gradient electric field/magnetic field comprehensive physical field environment.Electric field and gradient magnetic environment Superposition, realize in the same space under varying strength magnetic/electric field environment biological effect and biological response mechanism carry out Research.
As shown in Fig. 4-3, the first plate gradient coil 31 and the second plate gradient coil 32 are located below in setting up and down The second plate gradient coil 32 be equipped with a bracket 9, each planar excitation electrical field coil 33 is set to bracket 9 in parallel interval On, bracket 9 is for fixing the first plate gradient coil 31 and the second plate gradient coil 32.
Meanwhile bracket 9 includes at least three pillars 91 and frame 93, as shown in Fig. 3-1 and Fig. 3-2, in planar excitation electricity Field coil 33 is equipped with through-hole corresponding with 91 installation site of pillar, and planar excitation electrical field coil 33 is placed on respectively by through-hole On pillar 91, it is equipped on the pillar 91 between adjacent two planar excitations electrical field coil 33 for adjusting two planar excitation electric field lines Enclose the regulation pipe 92 of 33 spacing.Here regulation pipe 92 is preferably acrylic pipe.
In order to avoid external environment is adversely affected to electromagnetic field environment is formed by, electromagnetic field device 3 further includes cover Outside the first plate gradient coil 31 and the second plate gradient coil 32 without magnetic acrylic transparent sealing outer cover 34, form envelope The cell culture chamber closed, there are carbon dioxide stomatas and water cooling tube inlet outlet hole.Branch therein is placed on two plate gradient coils Inside, for the planar excitation electrical field coil of each layer as every confluent monolayer cells culturing rack, the spacing of adjacent two planar excitations electrical field coil can According to needing to be adjusted, hollow acrylic pipe is cut into unit length, pass through the nestable number with acrylic pipe in pillar upper layer Mesh adjusts the spacing in every layer of culture face, and culture is made be in different magnetic field environment culture, entire culturing room's outside culture hood and Internal culture pillar is avoided the influence to magnetic field environment and is facilitated observation using no magnetic acrylic transparent material.It is flat to give two Plate gradient coil current pulse mode, magnetic field strength disturbance, planar excitation electrical field coil generate excitation electrical field between culture, swash Coil design is encouraged using Archimedes's coil form, the area that coil spiral is surrounded obtains area using θ as integral parameter Element:
DA=(a θ)2/2dθ
A=a2/2∫[0,2π]θ2
=4a2π3/3
Host computer 1 is connected by USB data line 4 with digital analog converter 22, and digital analog converter 22 receives the number of host computer 1 Signal and output are that analog signal passes to gradient controller 23.Since the magnetic field gradient rise time needs from 0 to 100A 820us, under the conditions of two plate gradient coil current semi-load, the pulse application time of electric current is set as 500us to 200ms, because This, magnetic field pulse frequency highest can reach 2000Hz, and burst length duty ratio is no more than 5%.Utilize plate gradient coil shape At a stable gradient magnetic, adds additional various current impulses to be to be formed and interfered to entire field, induce in magnetic field Coil generates inductance potential, while it is basicly stable to retain magnetic field, forms the comprehensive field of an electro magnetic.Current sequence information is by ladder Operand value is further amplified in degree amplifier 25, powers via gradient power 24 to plate gradient coil, gradient current has wink Between change etc. require, it is desirable that power supply has the features such as carrying load ability is strong, and the rate of climb is fast, and consistency is good.
The present invention uses 150V, and 20A gradient power 24 is powered, in addition, realizing pulse train using high pressure caching capacitor 26 Be switched fast.Current signal is amplified to working value by gradient amplifier 25, and operating current passes through two plates setting up and down Gradient coil generates Gz gradient magnetic in coil inside, due to the synergistic effect of upper and lower two pieces of plates gradient coil internal magnetic field, Coil inside forms uniform gradient magnetic environment.In gradient magnetic inner space magnetic field environment from the inside of gradient coil plate extremely Theoretical zero magnetic environment is reduced to by high-intensity magnetic field at 2 hub of a spool point of distance.Gradient magnetic space is formed by be built-in with along ladder The multilayer planar excitation electrical field coil that direction is placed is spent, when applying gradient magnetic, in different planar excitation electrical field coils Magnetic field strength is related to axial position.It is trained being placed in the plane of planar excitation electrical field coil containing cell or tissue culture dish It supports, the magnetic field of the biological sample perception in different culture layers is strong and weak different, to realize in the same space to varying strength magnetic Biological effect and biological response mechanism under the environment of field are studied.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or It changes still within the protection scope of the invention.

Claims (10)

1. a kind of electric/magnetic field environment comprehensive generating system, which is characterized in that the system comprises host computer (1), gradient magnetics to send out Generating apparatus (2) and electromagnetic field device (3), the host computer (1) and the gradient magnetic generating device (2) pass through data line (4) Connection, the gradient magnetic generating device (2) are connect with the electromagnetic field device (3) by power supply line (5), for being the electricity Magnetic field device (3) provides stabilizing magnetic field, and the host computer (1) is the electromagnetic field by the gradient magnetic generating device (2) The adjusting of device (3) progress current impulse size and current pulse sequence;The electromagnetic field device (3) includes setting in parallel interval The the first plate gradient coil (31) and the second plate gradient coil (32) set and it is located at the first plate gradient coil (31) The multiple planar excitation electrical field coils (33) being set in distance between the second plate gradient coil (32), each plane Excitation electrical field coil (33) is set in parallel with the first plate gradient coil (31);The ladder is controlled by host computer (1) When spending field generator for magnetic (2) work, in the first plate gradient coil (31) and the second plate gradient coil (32) Between each planar excitation electrical field coil (33) surface form the magnetic field of distribution gradient, and in each planar excitation electricity Different electric fields is generated in field coil (33).
2. electric/magnetic field environment comprehensive generating system according to claim 1, which is characterized in that the gradient magnetic occurs Device (2) includes electromagnetic shielding rack (21) and the digital analog converter (22) being located in the electromagnetic shielding rack (21), gradient Controller (23), gradient power (24), gradient amplifier (25) and high pressure caching capacitor (26), the host computer (1) pass through number It is connect according to line (4) with the digital analog converter (22), the digital analog converter (22) and the gradient controller (23) pass through letter The connection of number line (6), the gradient controller (23) are slow with the gradient amplifier (25), high pressure respectively by signal wire (6) Deposit capacitor (26) connection;The gradient power (24) is electrically connected by power supply line (5) and the gradient amplifier (25), described Gradient amplifier (25) amplifies the electric current of gradient power (24) output according to the waveform that the gradient controller (23) exports, The gradient amplifier (25) and high pressure caching capacitor (26) and the first plate gradient coil (31) and the second plate Gradient coil (32) is electrically connected;The host computer (1) controls the control letter of gradient controller (23) the output multiple waveforms Number, high pressure caching capacitor (26) according to the control instruction of the gradient controller (23) be the electromagnetic field device (3) into Horizontal high voltage power supply.
3. electric/magnetic field environment comprehensive generating system according to claim 2, which is characterized in that the gradient magnetic occurs Device (2) further includes analog-digital converter (27), by signal wire (6) respectively with the electromagnetic field device (3), gradient controller (23) it connects, the analog-digital converter (27) acquires the first plate gradient coil (31) and the second plate gradient coil in real time (32) current signal in, and current signal collected is fed back into the gradient controller (23).
4. electric/magnetic field environment comprehensive generating system according to claim 3, which is characterized in that the first plate gradient line It is additionally provided with heat exchanging pipe (7) inside circle (31) and the second plate gradient coil (32), the heat exchanging pipe (7) and external water cooling Device (8) connection, for being cooled down for the first plate gradient coil (31) and the second plate gradient coil (32).
5. electric/magnetic field environment comprehensive generating system according to claim 4, which is characterized in that the gradient controller (23) waveform control signal exported is that continuous wave controls signal or interruption waveform control signal comprising sine wave, triangle One of wave, trapezoidal wave and square wave, output waveform frequency are 0~155Hz.
6. -5 any electric/magnetic field environment comprehensive generating system according to claim 1, which is characterized in that the plane swashs Encouraging electrical field coil (33) is Archimedes's shape planar coil.
7. electric/magnetic field environment comprehensive generating system according to claim 6, which is characterized in that the planar excitation electric field The surface of coil (33) is covered with Signa Gel coating (10), and is equipped at least one in its perimeter and is opened point electrode point I (331), position is equipped with an open point electrode point II (332), the opening point electrode point I (331), open point therebetween Closed circuit is formed between electrode points II (332) and the Signa Gel coating (10).
8. electric/magnetic field environment comprehensive generating system according to claim 7, which is characterized in that the first plate gradient Coil (31) is in setting up and down, the underlying second plate gradient coil with the second plate gradient coil (32) (32) bracket (9) are equipped with, each planar excitation electrical field coil (33) is set on the bracket (9) in parallel interval.
9. electric/magnetic field environment comprehensive generating system according to claim 8, which is characterized in that the bracket (9) includes at least Three pillars (91), the planar excitation electrical field coil (33) are equipped with corresponding with the pillar (91) installation site logical Hole, the planar excitation electrical field coil (33) are placed on each pillar (91) by the through-hole, adjacent two plane It is equipped on pillar (91) between excitation electrical field coil (33) for adjusting two planar excitation electrical field coil (33) spacing Regulation pipe (92);The regulation pipe (92) is acrylic pipe.
10. electric/magnetic field environment comprehensive generating system according to claim 1, which is characterized in that the electromagnetic field device (3) It further include covering in external transparent without magnetic acrylic of the first plate gradient coil (31) and the second plate gradient coil (32) Sealing cover (34).
CN201811499405.9A 2018-12-08 2018-12-08 Comprehensive generation system for electric/magnetic field environment Active CN109596670B (en)

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