CN109589302A - Silicone scar gel and preparation method thereof - Google Patents

Silicone scar gel and preparation method thereof Download PDF

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Publication number
CN109589302A
CN109589302A CN201811507484.3A CN201811507484A CN109589302A CN 109589302 A CN109589302 A CN 109589302A CN 201811507484 A CN201811507484 A CN 201811507484A CN 109589302 A CN109589302 A CN 109589302A
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CN
China
Prior art keywords
parts
silicone
present
preparation
scar gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811507484.3A
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Chinese (zh)
Inventor
黄德虎
陈献举
沈智群
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Letai Medical Technology Co Ltd
Original Assignee
Suzhou Letai Medical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Letai Medical Technology Co Ltd filed Critical Suzhou Letai Medical Technology Co Ltd
Priority to CN201811507484.3A priority Critical patent/CN109589302A/en
Publication of CN109589302A publication Critical patent/CN109589302A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/80Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention provides a kind of silicone scar gels and preparation method thereof, silicone scar gel is in parts by weight, comprising: 2-10 parts of silicone, 3-7 parts of ammonium chloride, 0.2-1 parts of triethanolamine, 0.2-8 parts of phenyl trimethicone, 0.3-0.5 parts of sodium benzoate, 10-30 parts of glycerol, 3-8 parts of purified water, 1-9 parts of octyl methoxycinnamate.The present invention is easy to use, is easy to absorb, good permeability, non-greasy.

Description

Silicone scar gel and preparation method thereof
Technical field
The present invention relates to a kind of gels and preparation method thereof, and in particular, to a kind of silicone scar gel and its preparation side Method.
Background technique
Scar, which repairs gel, has the function of anti-proliferation of fibroblast, anti-inflammatory and softening, cicatricial tissue.Existing scar It is inconvenient to use to repair gel, is not easy to absorb, poor air permeability is greasy.
Summary of the invention
For the defects in the prior art, the technical problem to be solved in the present invention is to provide a kind of silicone scar gel and its Preparation method, it is easy to use, it is easy to absorb, good permeability, non-greasy.
According to an aspect of the present invention, a kind of silicone scar gel is provided, which is characterized in that in parts by weight, It include: 2-10 parts of silicone, 3-7 parts of ammonium chloride, 0.2-1 parts of triethanolamine, 0.2-8 parts of phenyl trimethicone, benzoic acid 0.3-0.5 parts of sodium, 10-30 parts of glycerol, 3-8 parts of purified water, 1-9 parts of octyl methoxycinnamate.
Preferably, the pH value of the sodium benzoate is 4-6.
The present invention also provides a kind of preparation methods of silicone scar gel, which comprises the following steps:
Silicone, ammonium chloride, triethanolamine, purified water are put into a reaction container and stir evenly by step 1;
Step 2, then phenyl trimethicone, sodium benzoate, glycerol, octyl methoxycinnamate are added to reaction In bucket and heat;
Step 3, cooling half an hour simultaneously carry out plastics package.
Compared with prior art, the present invention is with following the utility model has the advantages that present silicone scar gel and its preparation side Method is easy to use, is easy to absorb, good permeability, non-greasy.
Specific embodiment
The present invention is described in detail combined with specific embodiments below.Following embodiment will be helpful to the technology of this field Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that the ordinary skill of this field For personnel, without departing from the inventive concept of the premise, various modifications and improvements can be made.These belong to the present invention Protection scope.
Present silicone scar gel is in parts by weight, comprising: 2-10 parts of silicone, 3-7 parts of ammonium chloride, triethanolamine 0.2-1 parts, 0.2-8 parts of phenyl trimethicone, 0.3-0.5 parts of sodium benzoate, 10-30 parts of glycerol, 3-8 parts of purified water, 1-9 parts of octyl methoxycinnamate.
The pH value of sodium benzoate is 4-6, and emulsifying effectiveness can be improved in this way.
The preparation method of present silicone scar gel the following steps are included:
Silicone, ammonium chloride, triethanolamine, purified water are put into a reaction container and stir evenly by step 1;
Step 2, then phenyl trimethicone, sodium benzoate, glycerol, octyl methoxycinnamate are added to reaction In bucket and heat;
Step 3, cooling half an hour simultaneously carry out plastics package.
Embodiment one
Present silicone scar gel is in parts by weight, comprising: 2 parts of silicone, 3 parts of ammonium chloride, triethanolamine 0.2 Part, 0.2 part of phenyl trimethicone, 0.5 part of sodium benzoate, 30 parts of glycerol, 8 parts of purified water, octyl methoxycinnamate 9 Part.
Embodiment two
Present silicone scar gel is in parts by weight, comprising: 10 parts of silicone, 7 parts of ammonium chloride, 1 part of triethanolamine, 8 parts of phenyl trimethicone, 0.3 part of sodium benzoate, 10 parts of glycerol, 3 parts of purified water, 1 part of octyl methoxycinnamate.
Embodiment three
Present silicone scar gel is in parts by weight, comprising: 6 parts of silicone, 5 parts of ammonium chloride, triethanolamine 0.5 Part, 4 parts of phenyl trimethicone, 0.4 part of sodium benzoate, 20 parts of glycerol, 5 parts of purified water, 5 parts of octyl methoxycinnamate.
The present invention to the surface of a wound scar processing after, be applied with or be applied to gauze and stick, once a day or the next day it is primary.The present invention For assisting improving dermal pathology scars, the formation of auxiliary prevention dermal pathology scars.Present silicone scar gel and Preparation method is easy to use, is easy to absorb, good permeability, non-greasy.
Specific embodiments of the present invention are described above.It is to be appreciated that the invention is not limited to above-mentioned Particular implementation, those skilled in the art can make various deformations or amendments within the scope of the claims, this not shadow Ring substantive content of the invention.

Claims (3)

1. a kind of silicone scar gel, which is characterized in that in parts by weight, comprising: 2-10 parts of silicone, 3-7 parts of ammonium chloride, 0.2-1 parts of triethanolamine, 0.2-8 parts of phenyl trimethicone, 0.3-0.5 parts of sodium benzoate, 10-30 parts of glycerol, purifying 3-8 parts of water, 1-9 parts of octyl methoxycinnamate.
2. silicone scar gel according to claim 1, which is characterized in that the pH value of the sodium benzoate is 4-6.
3. a kind of preparation method of silicone scar gel, which comprises the following steps:
Silicone, ammonium chloride, triethanolamine, purified water are put into a reaction container and stir evenly by step 1;
Step 2, then phenyl trimethicone, sodium benzoate, glycerol, octyl methoxycinnamate are added in reaction container And it heats;
Step 3, cooling half an hour simultaneously carry out plastics package.
CN201811507484.3A 2018-12-11 2018-12-11 Silicone scar gel and preparation method thereof Pending CN109589302A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811507484.3A CN109589302A (en) 2018-12-11 2018-12-11 Silicone scar gel and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811507484.3A CN109589302A (en) 2018-12-11 2018-12-11 Silicone scar gel and preparation method thereof

Publications (1)

Publication Number Publication Date
CN109589302A true CN109589302A (en) 2019-04-09

Family

ID=65961623

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811507484.3A Pending CN109589302A (en) 2018-12-11 2018-12-11 Silicone scar gel and preparation method thereof

Country Status (1)

Country Link
CN (1) CN109589302A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420118A (en) * 1990-11-30 1995-05-30 Richardson-Vicks Inc. Gel type cosmetic compositions
CN104546552A (en) * 2013-10-09 2015-04-29 远东新世纪股份有限公司 Scar gel composition
CN105362210A (en) * 2015-11-19 2016-03-02 朱坤福 Scar gel and preparation method thereof
CN108403623A (en) * 2018-05-29 2018-08-17 南京华开生物科技有限公司 silicone scar gel

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420118A (en) * 1990-11-30 1995-05-30 Richardson-Vicks Inc. Gel type cosmetic compositions
CN104546552A (en) * 2013-10-09 2015-04-29 远东新世纪股份有限公司 Scar gel composition
CN105362210A (en) * 2015-11-19 2016-03-02 朱坤福 Scar gel and preparation method thereof
CN108403623A (en) * 2018-05-29 2018-08-17 南京华开生物科技有限公司 silicone scar gel

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Application publication date: 20190409