CN109589183B

CN109589183B - Dissection device for animal experiments

Info

Publication number: CN109589183B
Application number: CN201811446510.6A
Authority: CN
Inventors: 邵秉一; 杨德琴
Original assignee: Stomatological Hospital of Chongqing Medical University
Current assignee: Stomatological Hospital of Chongqing Medical University
Priority date: 2018-11-29
Filing date: 2018-11-29
Publication date: 2020-10-30
Anticipated expiration: 2038-11-29
Also published as: CN109589183A

Abstract

The invention relates to the field of animal experiment devices, and particularly discloses an anatomical device for animal experiments, which comprises an oval base, wherein a circle of oval sliding groove is formed in the edge of the base, a chest fixing mechanism is movably connected in the sliding groove, and the chest fixing mechanism comprises two oppositely-arranged chest fixing components; the middle part of base rotates and is connected with supporting platform, and the equal sliding connection of two chest fixed components is in supporting platform's both sides portion. The problem of influence dissection effect among the prior art because lack fixing device is solved.

Description

Dissection device for animal experiments

Technical Field

The invention relates to the field of animal experiment devices, in particular to an anatomy device for animal experiments.

Background

Osteoclasts are multinucleated cells fused from mononuclear precursor cells from the monocyte/macrophage lineage, which are the major bone-resorbing cells and play a key role in skeletal development and regulation of bone mass. There are many methods for culturing osteoclasts in vitro, and the most common method is to extract mouse bone marrow cells to induce them to form multinucleated giant cells, mainly because: firstly, the bone marrow has a high number of monocytes capable of forming osteoclasts, which makes osteoclasts more potent; second, the mononuclear cells in the bone marrow are more primitive and contain more mesenchymal cells and mononuclear cell precursors.

Mice are generally sacrificed and dissected prior to extraction of the mouse bone marrow cells in order to obtain the mouse bone marrow cells. In the prior art, when a mouse is dissected after neck breakage, the existing containing disc in a laboratory is usually utilized for dissection, and in the dissection process, a dissector needs one hand to press and fix the leg of the mouse and the other hand to dissect the leg of the mouse. The mouse is poor in fixing effect due to the lack of a fixing device, so that the tissue of the mouse is easily scraped by an anatomist when the anatomist dissects, and the anatomical effect is influenced.

Disclosure of Invention

The invention aims to provide an animal experiment dissecting device to solve the problem that dissecting effect is affected due to lack of a fixing device in the prior art.

In order to achieve the purpose, the technical scheme of the invention is as follows: an anatomy device for animal experiments comprises an oval base, wherein a circle of oval sliding groove is arranged at the edge of the base, a chest fixing mechanism is movably connected in the sliding groove, and the chest fixing mechanism comprises two oppositely arranged chest fixing components; the middle part of base rotates and is connected with supporting platform, and the equal sliding connection of two chest fixed components is in supporting platform's both sides portion.

The principle and the beneficial effects of the technical scheme are as follows: this technical scheme base plays the effect of whole support, and supporting platform is used for supporting the animal of treating dissecting, and chest fixed establishment is used for the fixed chest of treating the animal of dissecting, because in chest fixed establishment sliding connection's the spout on the base, and two chest fixed subassemblies set up relatively, the accessible rotates supporting platform and realizes removing the position of two chest fixed subassemblies in the spout, and then realizes the regulation to the distance between two chest fixed subassemblies. When the two chest fixing components are respectively positioned at two ends of the long axis of the oval sliding chute, the distance between the two chest fixing components is large, and animals (such as rats) with large volume can be clamped and fixed; when the two chest fixing components move to the two ends of the short axis of the oval sliding chute, the distance between the two chest fixing components is small, and an animal (such as a mouse) with small volume can be clamped and fixed. The fixing of animal before the dissection has been realized to this scheme, and the personnel of conveniently dissecting dissect the animal, and can adjust the distance between the fixed subassembly of two chests according to the volume rotation support platform who treats the dissection animal for the device can be fixed the animal of different volumes, and application scope is wide and convenient operation.

Further, the chest fixing component comprises sliding balls movably connected in the sliding grooves, fixing rods are fixedly connected with the sliding balls, one ends, far away from the sliding balls, of the fixing rods are fixedly connected with fixing blocks, one side face, far away from the fixing rods, of each fixing block is set to be a cambered surface, one ends, far away from the sliding balls, of the fixing rods are connected to the supporting platform in a sliding mode, and limiting parts used for fixing the positions of the sliding balls are arranged in the sliding grooves.

When the distance between two chest fixing components needs to be moved, the supporting platform is rotated, the supporting platform rotates to drive the fixing rod which is connected with the supporting platform in a sliding mode to rotate, the fixing rod enables the sliding ball at the end of the fixing rod to move along the oval sliding groove in the rotating process, so that the distance between the two fixing blocks can be adjusted, after the fixing rod is moved in place, the limiting part is used for limiting the position of the sliding ball, the sliding ball is prevented from continuously moving in the clamping process, due to the arc surface design on the fixing blocks, the fixing blocks can be better attached to an animal to be clamped, and the fixing effect is enhanced.

Furthermore, a blood collecting groove is arranged on the base at the inner side of the sliding groove, and a blood dropping hole is arranged in the blood collecting groove.

The blood generated in the process of dissecting animals, the sewage generated in the process of cleaning the blood and dissecting tissues can flow downwards into the blood collection groove and be treated and collected uniformly along the blood dripping holes on the blood collection groove, so that the cleanness of the dissecting environment is ensured in the dissecting process.

Further, the middle part of base is fixedly connected with the round platform, is equipped with a plurality of guiding gutters that communicate with blood collection groove on the lateral wall of round platform, supporting platform rotates to be connected on the round platform.

The design of round platform makes the dirty bloody stain of the upward and downward flow of supporting platform at round platform top can follow the guiding gutter on the round platform and flow down to the blood collection inslot, and the guiding gutter has the effect of direction to the bloody stain, and the speed that the bloody stain flows down can be accelerated to the lateral wall of round platform slope, realizes the quick collection of bloody stain.

Furthermore, supporting platform is the supporting platform of rectangle, all sliding connection has shank fixed establishment on supporting platform's the four corners.

The supporting platform design accords with the general shape needs of dissecting the animal for the rectangle, and shank fixed establishment on the supporting platform is used for the four limbs of fixed animal, with shank fixed establishment sliding connection on the supporting platform, can adjust shank fixed establishment's position according to actual need, and then realizes the different fixed of opening the angle of animal four limbs, still can be applicable to the fixed of the animal of equidimension not simultaneously, increases the application range of device.

Further, shank fixed establishment includes the fixed frame of sliding connection on supporting platform, and the lateral wall of fixed frame is equipped with the deep hole, and the one end rigid coupling of fixed frame has the connection piece, is equipped with the connecting hole on the connection piece, be equipped with the fixed orifices on supporting platform's the side, be equipped with the fixed subassembly of shank in the fixed frame.

The fixing frame plays a role of integrally supporting the leg fixing mechanism, the deep hole provides a channel for the four limbs of the animal to be placed, after the leg fixing mechanism moves in place along the supporting platform, the connecting hole in the connecting sheet and the fixing hole in the supporting platform can be inserted with the fixing piece to fix the position of the leg fixing mechanism, and the operation is convenient.

Furthermore, the fixed subassembly of shank includes the tight piece of support of rigid coupling in fixed frame one side, supports to rotate on the tight piece and is connected with the lead screw, threaded connection has the extrusion piece on the lead screw, extrusion piece sliding connection is in fixed frame, the coaxial rigid coupling of the one end that supports the tight piece is kept away from to the lead screw has first bevel gear, first bevel gear meshing has the second bevel gear, the coaxial rigid coupling of second bevel gear has the regulation pole, the one end that the second bevel gear was kept away from to the regulation pole passes the lateral wall of fixed frame and the rigid coupling has the regulating block.

When the four limbs of an animal are placed in the fixing frame, the adjusting block is rotated, the adjusting block rotates to drive the adjusting rod fixedly connected with the adjusting block to rotate, and further drives the second bevel gear coaxially and fixedly connected with the adjusting rod to rotate, the second bevel gear is meshed with the first bevel gear to rotate, so that the first bevel gear drives the screw rod to rotate, the screw rod enables the extrusion block in threaded connection with the screw rod to axially move along the screw rod in the rotating process, and the extrusion block and the abutting block are matched to clamp the limbs of the animal. The clamping degree can be controlled by rotating the adjusting block, and the leg fixing component can be suitable for clamping animal limbs with different diameters, so that the application range of the device is further enlarged.

Further, sponge layers are wrapped on the abutting block and the extruding block.

The sponge layers on the abutting block and the extrusion block have the function of protecting the limbs of the animal, and the extrusion block and the abutting block can be prevented from breaking the tissues of the limbs of the animal.

Drawings

FIG. 1 is a top view of an animal experimental dissector device according to an embodiment of the present invention;

fig. 2 is an enlarged view at a1 in fig. 1.

Detailed Description

The following is further detailed by way of specific embodiments:

reference numerals in the drawings of the specification include: the blood collection and injection device comprises a base 1, a sliding groove 2, a supporting platform 3, a sliding ball 4, a fixing rod 5, a fixing block 6, a blood collection groove 7, a blood dripping hole 8, a circular truncated cone 9, a diversion groove 10, a fixing frame 11, a connecting sheet 12, a connecting hole 13, a fixing hole 14, a butting block 15, a screw rod 16, an extrusion block 17, a first bevel gear 18, a second bevel gear 19, an adjusting rod 20 and an adjusting block 21.

The embodiment is basically as shown in the attached figures 1 and 2: the utility model provides an animal is dissection device for experiments, includes oval base 1, and the middle part rigid coupling of base 1 has round platform 9, is equipped with a plurality of guiding gutters 10 on the lateral wall of round platform 9, and the top center department of round platform 9 rotates and is connected with rectangular supporting platform 3. The top edge of base 1 is equipped with oval-shaped spout 2 of round, is equipped with oval-shaped blood collection groove 7 on the base 1 of spout 2 inboard, is equipped with blood dripping hole 8 in the blood collection groove 7, and blood collection groove 7 communicates with guiding gutter 10.

A chest fixing mechanism is movably connected in the sliding chute 2 and comprises two fixing rods 5 which are oppositely arranged, sliding balls 4 are welded at the ends, far away from each other, of the two fixing rods 5, and the sliding balls 4 are connected in the sliding chute 2 in a sliding manner; the fixing blocks 6 are welded at the ends, close to each other, of the two fixing rods 5, the side face, opposite to the two fixing blocks 6, is provided with a cambered surface, the fixing blocks 6 can be tightly attached to the chest of an animal to be dissected due to the design of the cambered surface, and the fixing effect is enhanced; the two fixing rods 5 are slidably connected to the left and right sides of the supporting platform 3 at their ends close to each other, and a plurality of restraining members for fixing the position of the sliding ball 4 are disposed in the sliding groove 2, and the restraining members in this embodiment are a plurality of straps (not shown in the figure) disposed on the side wall of the sliding groove 2.

Equal vertical sliding connection has shank fixed establishment in supporting platform 3's the four corners, and shank fixed establishment includes the fixed frame 11 of vertical sliding connection on supporting platform 3, and fixed frame 11 in this embodiment all sets up to the center slope of keeping away from supporting platform 3, and the free end of fixed frame 11 all sets up to the 3 outside slopes of supporting platform promptly, so set up the four limbs of being convenient for place the animal. The side wall of the fixed frame 11 is provided with a deep hole, one end of the fixed frame 11 is fixedly connected with a connecting sheet 12, the connecting sheet 12 is provided with a connecting hole 13, and the side edge of the supporting platform 3 is provided with a fixing hole 14. A leg fixing assembly is arranged in the fixed frame 11, and as shown in fig. 2, the leg fixing assembly comprises a propping block 15 fixedly connected to the left side in the fixed frame 11, a screw rod 16 is rotatably connected to the propping block 15, an extrusion block 17 is connected to the screw rod 16 in a threaded manner, the extrusion block 17 is slidably connected in the fixed frame 11, sponge layers are wrapped on the propping block 15 and the extrusion block 17, the sponge layers have the effect of buffering and protecting animal limbs, and the extrusion block 17 and the propping block 15 can be prevented from crushing animal limb tissues; a first bevel gear 18 is coaxially and fixedly connected to one end of the screw rod 16 far away from the abutting block 15, a second bevel gear 19 is meshed with the first bevel gear 18, an adjusting rod 20 is coaxially and fixedly connected to the second bevel gear 19, and one end of the adjusting rod 20 far away from the second bevel gear 19 penetrates through the side wall of the fixed frame 11 and is fixedly connected with an adjusting block 21.

The specific implementation process is as follows: when the animal of waiting to dissect is the mouse, place the mouse on supporting platform 3, the chest diameter of mouse is little, at this moment, rotates the supporting platform 3 at base 1 middle part for sliding connection rotates along with supporting platform 3 at the dead lever 5 of supporting platform 3 left and right both sides portion, and the sliding ball 4 of dead lever 5 tip slides in oval-shaped spout 2 this moment. In the process that the two sliding balls 4 slide along the sliding groove 2 from two ends of a long shaft of the sliding groove 2 to two ends of a short shaft of the sliding groove 2, the distance between the two sliding balls 4 is gradually reduced, and the length of the fixing rod 5 is fixed, so that the distance between the two fixing blocks 6 is also gradually reduced, namely the two fixing blocks 6 move close to each other, when the two fixing blocks 6 move to the chest capable of clamping a mouse, the rotation of the supporting platform 3 is stopped, the fixing rod 5 is fixed by a binding band, and the chest of the mouse is fixed.

After the chest of the mouse is fixed, the four limbs of the mouse are fixed, the legs of the mouse penetrate through a deep hole in the fixing frame 11, the legs of the mouse are located between the abutting block 15 and the extrusion block 17, then an operator rotates the adjusting block 21 in the forward direction, the adjusting block 21 rotates to drive the adjusting rod 20 fixedly connected with the adjusting block to rotate, the second bevel gear 19 coaxially and fixedly connected with the adjusting rod 20 is driven to rotate, the second bevel gear 19 is meshed with the first bevel gear 18 to rotate, the first bevel gear 18 drives the screw rod 16 to rotate, the screw rod 16 enables the extrusion block 17 in threaded connection with the screw rod 16 to axially move along the screw rod 16 in the rotating process, and the extrusion block 17 moves towards one side close to the abutting block 15 and is matched with the abutting block 15 to clamp the limbs of the animal.

The rest three legs of the mouse are fixed by repeating the process, and the fixed frames 11 are connected to the supporting platform 3 in a sliding mode, so that the positions of the four fixed frames 11 can be adjusted according to actual needs in the actual anatomical process, and the four limbs of the mouse are in the optimal anatomical angle. When the positions of the four limbs of the mouse are adjusted, an inserting rod is taken and sequentially penetrates through the fixing hole 14 and the connecting hole 13, and the four limbs of the mouse are fixed.

When in dissection, blood of a mouse and sewage generated when an dissected part is cleaned flow downwards into the diversion trench 10 on the side wall of the circular truncated cone 9 from the supporting platform 3, flow into the blood collection trench 7 along the diversion trench 10, and finally flow out along the blood dropping hole 8 to be collected uniformly. After the dissection is finished, the operator reversely rotates the adjusting block 21, and the same principle indicates that the extrusion block 17 moves along the axial direction of the screw rod 16 away from one side of the abutting block 15, so that the limbs of the mouse are separated from the fixed frame 11; then untie the bandage, rotate supporting platform 3 once more, make two smooth balls 4 remove to the both ends of the major axis of oval spout 2 for two fixed blocks 6 keep away from each other and remove, no longer fix the chest of mouse, then take off the mouse from supporting platform 3, properly lay.

When the animal of waiting to dissect is the rat, place the rat on supporting platform 3, the chest diameter of rat is great, rotate supporting platform 3 this moment, make sliding connection at supporting platform 3 left and right both sides portion's dead lever 5 rotate along with supporting platform 3, the smooth ball 4 of dead lever 5 tip slides to the both ends of the major axis of spout 2 from the both ends of the minor axis of spout 2 in oval spout 2 this moment, the distance between two fixed blocks 6 also increases gradually, when two fixed blocks 6 move can hold the chest of waiting to centre gripping rat, the rotation of supporting platform 3 stops, and fix the position of dead lever 5 with the bandage, accomplish the fixed of rat chest. The procedure for the limb fixation of the rat is the same as that for the limb fixation of the mouse.

This technical scheme has realized dissecting the fixed of preceding animal, makes things convenient for the dissection personnel to dissect the animal, and can adjust the distance between the fixed subassembly of two chests according to the volume rotary supporting platform 3 of waiting to dissect the animal for the device can be fixed the animal of different volumes, and application scope is wide and convenient operation.

The foregoing is merely an example of the present invention and common general knowledge in the art of designing and/or characterizing particular aspects and/or features is not described in any greater detail herein. It should be noted that, for those skilled in the art, without departing from the technical solution of the present invention, several variations and modifications can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicability of the patent. The scope of the claims of the present application shall be determined by the contents of the claims, and the description of the embodiments and the like in the specification shall be used to explain the contents of the claims.

Claims

1. A dissecting device for animal experiments, which is characterized in that: the chest fixing mechanism comprises an oval base, wherein a circle of oval sliding groove is formed in the edge of the base, a chest fixing mechanism is movably connected in the sliding groove, and the chest fixing mechanism comprises two oppositely-arranged chest fixing components; the middle part of base rotates and is connected with supporting platform, and the equal sliding connection of two fixed subassemblies in chest is in supporting platform's both sides portion, the fixed subassembly of chest all includes the smooth ball of swing joint in the spout, and the smooth ball rigid coupling has the dead lever, and the one end rigid coupling that the smooth ball was kept away from to the dead lever has the fixed block, and the fixed block is kept away from a side of dead lever and is set up to the cambered surface, and the dead lever one end sliding connection of keeping away from the smooth ball is equipped with the locating part that is used for fixed.

2. The animal experimental dissecting device of claim 1, wherein: a blood collection groove is arranged on the base on the inner side of the sliding groove, and a blood dropping hole is formed in the blood collection groove.

3. The animal experimental dissecting device of claim 2, wherein: the middle part rigid coupling of base has the round platform, is equipped with a plurality of guiding gutters that communicate with blood collection groove on the lateral wall of round platform, supporting platform rotates to be connected on the round platform.

4. A dissecting device for animal experiments according to claim 3, characterized in that: the supporting platform is a rectangular supporting platform, and the four corners of the supporting platform are connected with leg fixing mechanisms in a sliding mode.

5. The animal experimental dissecting device of claim 4, wherein: the shank fixed establishment includes the fixed frame of sliding connection on supporting platform, and the lateral wall of fixed frame is equipped with the hole of going into deeply, and the one end rigid coupling of fixed frame has the connection piece, is equipped with the connecting hole on the connection piece, be equipped with the fixed orifices on supporting platform's the side, be equipped with the fixed subassembly of shank in the fixed frame.

6. The animal experimental dissecting device of claim 5, wherein: the leg fixing assembly comprises a supporting block fixedly connected to one side of the fixing frame, a lead screw is rotatably connected to the supporting block, an extrusion block is connected to the lead screw in a threaded mode, the extrusion block is slidably connected into the fixing frame, a first bevel gear is fixedly connected to one end, far away from the supporting block, of the lead screw in a coaxial mode, a second bevel gear is meshed with the first bevel gear, an adjusting rod is fixedly connected to the second bevel gear in a coaxial mode, and one end, far away from the second bevel gear, of the adjusting rod penetrates through the side wall of the fixing frame and.

7. The animal experimental dissecting device of claim 6, wherein: sponge layers are wrapped on the abutting blocks and the extruding blocks.