CN109580964A - Sample testing method, sample testing apparatus and pattern detection system - Google Patents

Sample testing method, sample testing apparatus and pattern detection system Download PDF

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Publication number
CN109580964A
CN109580964A CN201811378176.5A CN201811378176A CN109580964A CN 109580964 A CN109580964 A CN 109580964A CN 201811378176 A CN201811378176 A CN 201811378176A CN 109580964 A CN109580964 A CN 109580964A
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China
Prior art keywords
detection
sample
detected
project
detection device
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CN201811378176.5A
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Chinese (zh)
Inventor
吴岭
彭龙
范旭
戴立忠
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Sansure Biotech Inc
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Sansure Biotech Inc
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Priority to CN201811378176.5A priority Critical patent/CN109580964A/en
Publication of CN109580964A publication Critical patent/CN109580964A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00871Communications between instruments or with remote terminals

Abstract

A kind of sample testing method, device, system, computer equipment and storage medium, the method of one embodiment includes: to send detection instruction to the corresponding detection device of project to be detected, and the sample that the detection instruction detects sample placement location to control the detection device to it detects;Obtain the pattern detection intermediate result that the detection device returns;The pattern detection intermediate result is analyzed, final sample testing result corresponding with the project to be detected is obtained.The present embodiment can make main control device and detection device that can complete complete detection and analysis process with work compound, improve the efficiency of pattern detection.

Description

Sample testing method, sample testing apparatus and pattern detection system
Technical field
This application involves medical detection technologies, more particularly to a kind of sample testing method, sample testing apparatus, sample This detection system, computer equipment and computer storage medium.
Background technique
Current field of medical technology usually requires to be related to the detection to medical sample, such as blood sample, urine specimen Etc. detection, with can by the testing result of medical sample be reference, accordingly assess patient health status, whether suffer from disease Disease and comprehensive determining subsequent therapeutic scheme etc..However, at present when carrying out the detection of medical sample, usually from patient (usually the containers such as test tube are held the medical sample of offer, and the vessel surfaces such as test tube post bar code or by other means Indicate the corresponding patient information of the sample) in sampled after obtaining sample, which is placed into corresponding detection Sample is detected by detection device in the placement of equipment position to be detected, and detection device can obtain final detection As a result it is exported.
Pattern detection mode as described above, detection device need to execute complete detection and analysis mistake to sample Journey is fed back and is exported to obtain final detection result.To there is relatively high requirement to the processing capacity of detection device, And when the sample for needing to detect is more, subsequent pattern detection needs to wait longer time that could obtain final detection knot Fruit influences detection efficiency.
Summary of the invention
Based on this, it is necessary in view of the above technical problems, provide a kind of sample testing method, sample testing apparatus, sample Detection system, computer equipment and computer storage medium.
A kind of sample testing method, method include:
Detection instruction is sent to the corresponding detection device of project to be detected, the detection instruction is set to control the detection The standby sample that sample placement location is detected to it detects;
Obtain the pattern detection intermediate result that the detection device returns;
The pattern detection intermediate result is analyzed, final sample detection corresponding with the project to be detected is obtained As a result.
A kind of sample testing apparatus, comprising:
Control module, for sending detection instruction to the corresponding detection device of project to be detected, the detection instruction to It controls the detection device and detects the sample of sample placement location to it and detect;
Intermediate result obtains module, the pattern detection intermediate result returned for obtaining the detection device;
Analysis module obtains corresponding with the project to be detected for analyzing the pattern detection intermediate result Final sample testing result.
A kind of pattern detection system, including main control device and detection device;
Main control device, for sending detection instruction, the detection instruction to the corresponding detection device of project to be detected The sample for detecting sample placement location to it to control the detection device detects, and obtains the detection device and return Pattern detection intermediate result, the pattern detection intermediate result is analyzed, obtain it is corresponding with the project to be detected Final sample testing result;
Detection device detects sample placement location to it based on the detection instruction for receiving the detection instruction Sample is detected, and obtains pattern detection intermediate result, and return to the pattern detection intermediate result to the main control device.
A kind of computer equipment, including memory and processor, the memory are stored with computer program, the processing Device performs the steps of when executing the computer program
Detection instruction is sent to the corresponding detection device of project to be detected, the detection instruction is set to control the detection The standby sample that sample placement location is detected to it detects;
Obtain the pattern detection intermediate result that the detection device returns;
The pattern detection intermediate result is analyzed, final sample detection corresponding with the project to be detected is obtained As a result.
A kind of computer readable storage medium, is stored thereon with computer program, and the computer program is held by processor It is performed the steps of when row
Detection instruction is sent to the corresponding detection device of project to be detected, the detection instruction is set to control the detection The standby sample that sample placement location is detected to it detects;
Obtain the pattern detection intermediate result that the detection device returns;
The pattern detection intermediate result is analyzed, final sample detection corresponding with the project to be detected is obtained As a result.
Above-mentioned sample testing method, sample testing apparatus, pattern detection system, computer equipment and computer storage are situated between Matter is detected sending detection instruction to detection device with controlling detection device, and detection device is when being detected, and Complete detection and analysis process is not executed, it is only necessary to obtain pattern detection intermediate result, the pattern detection intermediate result of acquisition It can return to the main control device for sending the detection instruction, main control device again analyzes the pattern detection intermediate result, obtains Final sample testing result reduces so that detection device does not need to execute complete detection and analysis process to detection device Processing capacity requirement, the cost of detection device can be reduced, and analyze work and carried out by main control device, thus main control device Complete detection and analysis process can be completed with work compound with detection device, improve the efficiency of pattern detection.
Detailed description of the invention
Fig. 1 is the configuration diagram of pattern detection system in one embodiment;
Fig. 2 is the configuration diagram of pattern detection system in another embodiment;
Fig. 3 is the flow diagram of sample testing method in one embodiment;
Fig. 4 is the structural block diagram of sample testing apparatus in one embodiment;
Fig. 5 is the interaction flow schematic diagram of pattern detection process in one embodiment;
Fig. 6 is the internal structure chart of computer equipment in one embodiment.
Specific embodiment
It is with reference to the accompanying drawings and embodiments, right in order to which the objects, technical solutions and advantages of the application are more clearly understood The application is further elaborated.It should be appreciated that specific embodiment described herein is only used to explain the application, not For limiting the application.
Sample testing method provided by the embodiments of the present application can be applied in application environment as shown in Figure 1, the application Environment is related to including main control device and detection device, wherein main control device can pass through various possible communication modes and detection Equipment communication connection such as wireline cable connection, is wirelessly connected.Wherein, detection device is that can carry out detection to medical sample to obtain Intermediate detection result equipment, main control device can be it is any can to detection device send information, instruction with control detection Equipment executes detection operation, and the intermediate detection interpretation of result for combining detection device to return goes out setting for final pattern detection result It is standby.In some embodiments, which can be personal computer, laptop, smart phone, tablet computer and portable Any equipment that above-mentioned function may be implemented such as formula wearable device.
In some embodiments, refering to what is shown in Fig. 2, the application environment is also possible to further to sample extraction equipment, sweeps Retouch equipment and information management system, wherein information management system, which can be, to be set in independent management equipment, is also possible to It is integrated in above-mentioned main control device.Main control device can pass through various possible communication modes and sample extraction equipment, scanning device And the equipment communication connection where information management system.Scanning device can be used to the location information of scanned samples pipe, and sample mentions Taking equipment is that acquisition sample can be extracted to the sample of above-mentioned sample position, and detection device is can be to above-mentioned sampling The equipment that sample is detected, main control device can be and any can send out to scanning device, sample extraction equipment and detection device It delivers letters breath, the equipment to indicate the working condition of scanning device, sample extraction equipment and detection device.In some embodiments, The main control device can be that personal computer, laptop, smart phone, tablet computer and portable wearable device etc. are any can Equipment to realize above-mentioned function.
Refering to what is shown in Fig. 3, the sample testing method in one embodiment, includes the following steps S301 to step S303, it should Method can be executed by the main control device in Fig. 1,2.
Step S301: detection instruction is sent to the corresponding detection device of project to be detected, the detection instruction is to control The sample that the detection device detects sample placement location to it detects.
In one embodiment, which may include sample bar code information.Wherein it is possible to by providing operation circle Face inputs the corresponding sample bar code information of sample to be detected by operation user, sample to be detected can also be selected from system This bar code information, or sample bar code information is determined in other way.
For example, in some embodiments, can be scanned by bar code scan equipment and obtain sample bar code information, accordingly, It can also include step A1 and A2 before sending detection instruction.
A1: scan instruction is sent to bar code scan equipment.
Wherein, which is that can scan to obtain the sample bar code information of sample and sweeping for sample position information Retouch equipment, each putting position of the bar code scan equipment to scan the bar code obtained in sample tube, on sample tube placement equipment It installs in the case where being equipped with bar code information, the position bar code information for obtaining each placement location can also be scanned, obtained each sample The corresponding position bar code information of bar code information, to determine sample position information, in other embodiments, bar code scan equipment can also With in other way come realize each sample tube position positioning, to obtain the corresponding sample position of each sample bar code information Information.Wherein, which is the device that can place each sample tube.
A2: the scanning information that the bar code scan equipment is returned based on the scan instruction, the scanning information packet are received It includes: the sample position information on sample tube placement equipment, and the sample bar code corresponding with sample position information that scanning obtains Information.
To be based on scan instruction, main control device can obtain bar code scan equipment to each on sample tube placement equipment The corresponding sample tube of sample position information is scanned the corresponding sample bar code information of acquisition.In some embodiments, in item Code scanning device is based on after scan instruction scanning completion, information can be completed with feedback scan.Main control device can also be into One step receives the scanning that bar code scan equipment returns and information is completed, consequently facilitating doing after receiving scanning and information is completed Further handle.
In one embodiment, above-mentioned project to be detected can be to be detected by operation user's input by providing operation interface Project can also select project to be detected from all kinds of detection projects provided in system, can also be based on sample bar code information The relevant information of corresponding user selects project to be detected, or determines project to be detected in other way.
For example, in some embodiments, sample bar code information can be based on, obtained from information management system it is corresponding to Detection project accordingly, can also be including step B1 extremely before sending detection instruction to the corresponding detection device of project to be detected B3。
B1: inquiry instruction is sent to information management system, the inquiry instruction carries the sample bar code information.One reality Apply in example, the information management system can be LIS system (Laboratory Information Management System, Laboratory Information Management System aims at a set of information management system of hospital laboratory design).Certainly, the information management system It is also possible to the system of other storage and management patient informations.
B2: obtaining the query result that the information management system is returned based on the inquiry instruction, and the query result is taken The patient information of band user corresponding with the sample bar code information.
In information management system, it is stored with patient information, patient information may include various information relevant to patient, Such as patient's name, age, gender, patient barcode's information, diagnosis and treatment department, attending physician, inspection project.Therefore, based on trouble The bar code information of person can inquire in information management system and obtain patient information.
B3: the project to be detected is determined from the patient information.
In some embodiments, the patient information that information management system returns, may include that sample bar code information is corresponding All information of user, at this point, can be and extracted from this all information when determining project to be detected from patient information Inspection project out, and project to be detected is determined based on inspection project.
In some embodiments, the patient information that information management system returns can only include sample bar code information and send The relevant informations such as inspection project determine project to be detected so as to be directly based upon inspection project etc..
In one embodiment, the detection sample placement location of detection device can be had been placed in determining sample When, then detection instruction is sent to detection device.Therefore, in one embodiment, to detection corresponding with the project to be detected It, can be described with comprising steps of receive sample that the detection device returns placement information before equipment sends detection instruction Placement information may include that the detection device of the detection device identifies to sample.
In one embodiment, sample extraction equipment can be being determined to complete the extraction of sample and then to detection device Send detection instruction.Therefore, in one embodiment, detection instruction is being sent to detection device corresponding with the project to be detected It before, can be with comprising steps of obtaining the sample extraction that sample extraction equipment returns completes information, the sample extraction completes letter Breath includes: the sample bar code information.It can also include the item to be detected that sample extraction in one embodiment, which completes information, Mesh, in order to which main control device determines corresponding detection device.Sample extraction in one embodiment completes information The sample extraction device identification of the sample extraction equipment and/or the detection device mark of detection device, consequently facilitating master control is set Which detection device the standby sample for determining that sample extraction equipment is extracted has been placed on.
Accordingly, in one embodiment, main control device can also operate the sample extraction of sample extraction equipment and control System.Accordingly, before sending detection instruction to the corresponding detection device of project to be detected, can also include:
Send sample extraction instruction to sample extraction equipment, sample extraction instruction include the sample bar code information, The sample position information and the project to be detected, the sample extraction instruction are moved to control the sample extraction equipment It moves the corresponding position of the sample position information, the sample is extracted based on the corresponding sample extraction mode of the project to be detected The sample of this location information corresponding position obtains sample, and it is corresponding that sample is placed into the project to be detected The detection sample placement location of detection device.
In one embodiment, sample extraction equipment obtains sample, and the sample of acquisition is placed into corresponding After the detection sample placement location of detection device, above-mentioned sample extraction can also be fed back and complete information.
In some embodiments, above-mentioned sample extraction instruction can also include the sample extraction equipment mark of sample extraction equipment Know, sample extraction device identification is corresponding with the sample bar code information and sample position information.So as to which sample extraction is referred to Order is accurately sent to corresponding sample extraction equipment, and multiple sample extraction equipment can be set, can be to multiple sample extractions Equipment sends sample extraction instruction respectively Sample extraction device identification and sample bar code information, the sample position information and the project to be detected can not Together), so as to control multiple sample extraction instructions simultaneously, different samples is sampled respectively.
In some embodiments, above-mentioned sample extraction instruction can also include the detection of project to be detected or detection device Device identification, so which detection device the sample of acquisition should be placed by instruction sample extraction equipment accordingly Detect sample placement location.So as to carry out batch detection using multiple detection devices simultaneously.It is appreciated that in some implementations In example, sample extraction instruction can also sample extraction device identification simultaneously and detection device mark.
In some embodiments, above-mentioned detection instruction can also include detection parameters, and above-mentioned detection instruction is to control inspection Measurement equipment is detected based on sample of the detection parameters to detection sample placement location.
Detection parameters in one embodiment may include detection device operating parameter, detection one of environmental parameter or Two kinds, in other embodiments, which can also include other kinds of parameter.Wherein, detection device operating parameter To control the operating status of the detection device, detection environmental parameter is to indicate detection device or other equipment setting inspection The environmental parameter of environment where measurement equipment.
In one embodiment, by taking detection device is PCR detection device as an example, above-mentioned detection device operating parameter can be at this time It include: detection time, recurring number and fluorescence channel.
The detection parameters can be determined in conjunction with various possible modes, such as operated user and set by interactive interface. In one embodiment, corresponding detection parameters can be determined based on above-mentioned project to be detected, as can be based on default settings Template determines detection parameters, at this point, determine corresponding detection parameters based on the project to be detected, comprising:
Item detection template corresponding with the project to be detected, the item detection are transferred based on the project to be detected Template includes: detection device operating parameter, operating status of the detection device operating parameter to control the detection device, The detection parameters include the detection device operating parameter.
In one embodiment, can by operation user setting detect environmental parameter, so as to the input based on user come Obtain the detection environmental parameter.It in some embodiments, can include the detection environmental parameter in above-mentioned item detection template. In other embodiments, the detection environmental parameter can also be obtained in other way.
Step S302: the pattern detection intermediate result that the detection device returns is obtained.
For different types of detection device, the content for the pattern detection intermediate result for detecting and returning is had not Together.In one embodiment, by taking above-mentioned detection device is PCR detection device as an example, above-mentioned pattern detection intermediate result includes fluorescence Number.
Step S303: analyzing the pattern detection intermediate result, obtains corresponding most with the project to be detected Whole pattern detection result.
In one embodiment, the pattern detection intermediate result is analyzed, is obtained corresponding with the project to be detected Final sample testing result when, can be divided based on pattern detection intermediate result and corresponding pattern detection parameter information Analysis obtains final sample testing result corresponding with the project to be detected of the sample bar code information.Wherein, which examines Parameter information is surveyed, refers to the relevant sample parameter information of sample to be detected, it is corresponding to can be the sample to be detected in one embodiment Standard items relevant parameter information, by detection device be PCR detection device for, relevant parameter information at this time can be mark The information such as the concentration of quasi- product.
Wherein, the pattern detection parameter information can be obtained based on the setting of user, be also possible to set in advance in systems It sets.By taking the setting based on user obtains as an example, then detected in above-mentioned sent to detection device corresponding with the project to be detected Before instruction, further includes: receive pattern detection parameter setting instruction, the pattern detection parameter setting instruction includes pattern detection Parameter information.
With detection device for PCR detection device, for pattern detection result includes fluorescence number, the fluorescence number can be based on It is analyzed, is obtained corresponding most with the project to be detected of the sample bar code information with the pattern detection parameter information Whole pattern detection result.
In one embodiment, analyzed based on the fluorescence number and the pattern detection parameter information, obtain with it is described The corresponding final sample testing result of the project to be detected of sample bar code information, can specifically include:
Based on predetermined matching relationship, determining and the fluorescence number and the matched inspection of pattern detection parameter information It surveys as a result, and being detected the testing result as final sample corresponding with the project to be detected of the sample bar code information As a result, matching relationship of the matching relationship between fluorescence number, pattern detection parameter information and testing result.
In another embodiment, analyzed based on the fluorescence number and the pattern detection parameter information, obtain with The corresponding final sample testing result of the project to be detected of the sample bar code information, can specifically include:
The fluorescence number and pattern detection parameter information input are trained into the testing result Matching Model obtained in advance, It is determining with the fluorescence number and the matched testing result of pattern detection parameter information by the testing result Matching Model, And using the testing result as final sample testing result corresponding with the project to be detected of the sample bar code information.
Wherein, it when training obtains testing result Matching Model, can be carried out using following manner:
Obtain training sample, the training sample include training sample detection parameters information, training sample fluorescence number and Corresponding training sample testing result;
Initial detecting result Matching Model is trained based on the training sample;
When being unsatisfactory for training termination condition, after adjusting the model parameter in the initial detecting result Matching Model, The step of returning to the training sample, into next round training process;
When meeting training termination condition, final initial detecting result Matching Model is matched as the testing result Model.
Detailed training process can be by the way of any possible model training, and the embodiment of the present application does not do specific limit It is fixed.In other examples, the fluorescence number and the pattern detection parameter information can also be based on using other modes It is analyzed, obtains final sample testing result corresponding with the project to be detected of the sample bar code information, the application Embodiment is not specifically limited.
Refering to what is shown in Fig. 4, also providing a kind of sample testing apparatus in one embodiment, which includes:
Control module 401, for sending detection instruction to the corresponding detection device of project to be detected, the detection instruction is used The sample that sample placement location is detected to control the detection device to it detects;
Intermediate result obtains module 402, the pattern detection intermediate result returned for obtaining the detection device;
Analysis module 403 obtains and the project pair to be detected for analyzing the pattern detection intermediate result The final sample testing result answered.
In one embodiment, which may include sample bar code information.Wherein it is possible to by providing operation circle Face inputs the corresponding sample bar code information of sample to be detected by operation user, sample to be detected can also be selected from system This bar code information, or sample bar code information is determined in other way.
Accordingly, refering to what is shown in Fig. 4, device in one embodiment further include: further include: scan control module 408 is used for Scan instruction is sent to bar code scan equipment;And receive the scanning letter that the bar code scan equipment is returned based on the scan instruction Breath, the scanning information includes: the sample position information on sample tube placement equipment, and scanning obtain with sample bit confidence Cease corresponding sample bar code information.
In some embodiments, bar code scan equipment, can be with feedback scan after being completed based on scan instruction scanning Information is completed.Information is completed in the scanning that scan control module 408 can also further receive the return of bar code scan equipment, from And it is further handled convenient for being done after receiving scanning and information is completed.
In one embodiment, above-mentioned project to be detected can be to be detected by operation user's input by providing operation interface Project can also select project to be detected from all kinds of detection projects provided in system, can also be based on sample bar code information The relevant information of corresponding user selects project to be detected, or determines project to be detected in other way.
For example, in some embodiments, refering to what is shown in Fig. 4, the device can also include:
Information inquiry module 407, for sending inquiry instruction to information management system, the inquiry instruction carries the sample This bar code information;The query result that the information management system is returned based on the inquiry instruction is obtained, the query result is taken The patient information of band user corresponding with the sample bar code information;The project to be detected is determined from the patient information.
In one embodiment, which can be LIS system (Laboratory Information Management System, Laboratory Information Management System aim at a set of information management system of hospital laboratory design).When So, which is also possible to the system of other storage and management patient informations.
In one embodiment, sample extraction equipment can be being determined to complete the extraction of sample and then to detection device Send detection instruction.Accordingly, refering to what is shown in Fig. 4, the embodiment can also include in device;
Sample extraction control module 409 sends sample extraction instruction, the sample extraction instruction packet to sample extraction equipment The sample bar code information, the sample position information and the project to be detected are included, the sample extraction instruction is to control The sample extraction equipment is made to be moved to the corresponding position of the sample position information, be based on the corresponding sample of the project to be detected This extracting mode extracts the sample of the sample position information corresponding position, obtains sample, and sample is placed into The detection sample placement location of the corresponding detection device of the project to be detected.
In some embodiments, above-mentioned sample extraction instruction can also include the sample extraction equipment mark of sample extraction equipment Know, sample extraction device identification is corresponding with the sample bar code information and sample position information.So as to which sample extraction is referred to Order is accurately sent to corresponding sample extraction equipment, and multiple sample extraction equipment can be set, can be to multiple sample extractions Equipment sends sample extraction instruction respectively Sample extraction device identification and sample bar code information, the sample position information and the project to be detected can not Together), so as to control multiple sample extraction instructions simultaneously, different samples is sampled respectively.
In some embodiments, above-mentioned sample extraction instruction can also include the detection of project to be detected or detection device Device identification, so which detection device the sample of acquisition should be placed by instruction sample extraction equipment accordingly Detect sample placement location.So as to carry out batch detection using multiple detection devices simultaneously.It is appreciated that in some implementations In example, sample extraction instruction can also sample extraction device identification simultaneously and detection device mark.
In some embodiments, above-mentioned detection instruction can also include detection parameters, and above-mentioned detection instruction is to control inspection Measurement equipment is detected based on sample of the detection parameters to detection sample placement location.
Refering to what is shown in Fig. 4, the sample testing apparatus in one embodiment further include: detection parameters determining module 404 is used for Corresponding detection parameters are determined based on the project to be detected.
At this point, above-mentioned detection instruction further includes the detection parameters, the detection instruction is to control the detection device It is detected based on sample of the detection parameters to detection sample placement location.
Detection parameters in one embodiment may include detection device operating parameter, detection one of environmental parameter or Two kinds, in other embodiments, which can also include other kinds of parameter.Wherein, detection device operating parameter To control the operating status of the detection device, detection environmental parameter is to indicate detection device or other equipment setting inspection The environmental parameter of environment where measurement equipment.
In one embodiment, by taking detection device is PCR detection device as an example, above-mentioned detection device operating parameter can be at this time It include: detection time, recurring number and fluorescence channel.
The detection parameters can be determined in conjunction with various possible modes, such as operated user and set by interactive interface. In one embodiment, corresponding detection parameters can be determined based on above-mentioned project to be detected, as can be based on default settings Template determines detection parameters, at this point, detection parameters determining module 404, based on the project to be detected transfer with it is described to be checked The corresponding item detection template of survey project, the item detection template include: detection device operating parameter, the detection device fortune Operating status of the row parameter to control the detection device, the detection parameters include the detection device operating parameter.
In one embodiment, environmental parameter can be detected by operation user setting, i.e. detection parameters determining module 404 obtains The detection environmental parameter of user's input, so as to obtain the detection environmental parameter based on the input of user.In some implementations It can include the detection environmental parameter in above-mentioned item detection template in example.In other embodiments, other can also be passed through Mode obtain the detection environmental parameter.
In one embodiment, by taking detection device is PCR detection device as an example, above-mentioned detection device operating parameter can be at this time It include: detection time, recurring number and fluorescence channel.
For different types of detection device, the content for the pattern detection intermediate result for detecting and returning is had not Together.In one embodiment, by taking above-mentioned detection device is PCR detection device as an example, above-mentioned pattern detection intermediate result includes fluorescence Number.
In one embodiment, the pattern detection intermediate result is analyzed, is obtained corresponding with the project to be detected Final sample testing result when, can be divided based on pattern detection intermediate result and corresponding pattern detection parameter information Analysis obtains final sample testing result corresponding with the project to be detected of the sample bar code information.Wherein, which examines Parameter information is surveyed, refers to the relevant sample parameter information of sample to be detected, it is corresponding to can be the sample to be detected in one embodiment Standard items relevant parameter information, by detection device be PCR detection device for, relevant parameter information at this time can be mark The information such as the concentration of quasi- product.
Accordingly, it in one embodiment, as shown in figure 4, the device can also include detection parameters setup module 405, is used for Pattern detection parameter setting instruction is received, the pattern detection parameter setting instruction includes pattern detection parameter information.
At this point, analysis module 403, is divided based on the pattern detection intermediate result and the pattern detection parameter information Analysis obtains final sample testing result corresponding with the project to be detected of the sample bar code information.
By taking detection device is PCR detection device, pattern detection intermediate result includes fluorescence number as an example, at this point, analysis module 403, it is analyzed, is obtained described with the sample bar code information based on the fluorescence number and the pattern detection parameter information The corresponding final sample testing result of project to be detected.
In one embodiment, analysis module 403 is based on predetermined matching relationship, determining and the fluorescence number and institute State the matched testing result of pattern detection parameter information, and using the testing result as with described in the sample bar code information to The corresponding final sample testing result of detection project, the matching relationship are that fluorescence number, pattern detection parameter information and detection are tied Matching relationship between fruit.
In one embodiment, analysis module 403 instructs the fluorescence number and pattern detection parameter information input in advance Practice the testing result Matching Model obtained, is examined by the way that the testing result Matching Model is determining with the fluorescence number and the sample The matched testing result of parameter information is surveyed, and using the testing result as the project to be detected with the sample bar code information Corresponding final sample testing result.
Accordingly, the device in one embodiment can also include: model training module 406, for obtaining training sample, institute Stating training sample includes training sample detection parameters information, training sample fluorescence number and the intermediate knot of corresponding training sample detection Fruit;Initial detecting result Matching Model is trained based on the training sample;When being unsatisfactory for training termination condition, adjustment After model parameter in the initial detecting result Matching Model, the step of returning to the training sample, into next training in rotation Practice process;When meeting training termination condition, final initial detecting result Matching Model is matched as the testing result Model.
Specific about sample testing apparatus limits the restriction that may refer to above for sample testing method, herein not It repeats again.Modules in above-mentioned sample testing apparatus can be realized fully or partially through software, hardware and combinations thereof.On Stating each module can be embedded in the form of hardware or independently of in the processor in computer equipment, can also store in a software form In memory in computer equipment, the corresponding operation of the above modules is executed in order to which processor calls.
A pattern detection system is also provided in one embodiment, with reference to shown in Fig. 1 and 6, this in one embodiment is System may include main control device and detection device.
Wherein, main control device, for sending detection instruction, the detection to the corresponding detection device of project to be detected The sample that instruction detects sample placement location to control the detection device to it detects, and obtains the detection device The pattern detection intermediate result of return analyzes the pattern detection intermediate result, obtains and the project pair to be detected The final sample testing result answered.
The detection device detects sample putting position to it based on the detection instruction for receiving the detection instruction The sample set is detected, and obtains pattern detection intermediate result, and return to knot among the pattern detection to the main control device Fruit.
System in one embodiment can also include bar code scan equipment.It is also used at this point, stating main control device to described Bar code scan equipment sends scan instruction.The bar code scan equipment is based on scan instruction scanning and obtains sample tube placement equipment On sample position information and sample bar code information corresponding with sample position information, and to the main control device return sweep Feedback information is retouched, the scanning feedback information includes: the sample position information on sample tube placement equipment, and scanning obtains The sample bar code information corresponding with the sample position information obtained.
System in one embodiment can also include sample extraction equipment.At this point, the main control device, is also used to described Sample extraction equipment sends sample extraction instruction, and the sample extraction instruction includes the sample bar code information, the sample bit Confidence breath and the project to be detected.Wherein, sample extraction equipment, for being moved to institute based on sample extraction instruction It states the corresponding position of sample position information, the sample position is extracted based on the corresponding sample extraction mode of the project to be detected The sample of information corresponding position obtains sample, and sample is placed into the corresponding detection of the project to be detected and is set Standby detection sample placement location.
The detection device in one embodiment can be PCR detection device, and the pattern detection intermediate result includes glimmering Light number.
Bar code scan equipment in one embodiment may include two or more, and the scan instruction includes that bar code scan is set Standby mark, the scanning information includes bar code scan device identification.Above-mentioned sample extraction equipment in one embodiment can wrap Two or more is included, at this point, sample extraction instruction further includes sample extraction device identification.Above-mentioned detection device in one embodiment Including two or more, at this point, above-mentioned detection instruction further includes detection device mark, the sample extraction instruction further includes that detection is set Standby mark.
Specific about pattern detection system limits the restriction that may refer to above for sample testing method, device, Details are not described herein.Each step in above-mentioned sample testing method can be executed by the main control device in pattern detection system.
Refering to what is shown in Fig. 5, during below in conjunction with the pattern detection in one embodiment, respectively setting in pattern detection system Interactive process between standby is illustrated.
Sample information is obtained and when sample is sampled and detected needing to scan, and main control device is to bar code scan Equipment sends scan instruction.
After corresponding bar code scan equipment receives the scan instruction, acquisition sample tube storing is scanned based on scan instruction and is set Standby upper sample position information and sample bar code information corresponding with sample position information, and return and scan to main control device Information, scanning information include: the sample position information on sample tube placement equipment, and scanning obtain with the sample position The corresponding sample bar code information of information.
Main control device receives the scanning information, therefrom obtains sample bar code information to be detected, and to information management system System sends inquiry instruction, includes above-mentioned sample bar code information in the inquiry instruction.
After information management system receives the inquiry instruction, inquiry is obtained corresponding with sample bar code information from database The patient information of user, and inquiry response is returned to main control device accordingly, it include the trouble that above-mentioned inquiry obtains in the inquiry response Person's information.
After main control device receives inquiry response, based on the patient information in inquiry response, the sample bar code information is determined Corresponding project to be detected.After determining project to be detected, the detection parameters of the project to be detected are on the one hand determined, on the other hand Sample extraction instruction is sent to sample extraction equipment, sample extraction instruction includes sample bar code information, corresponding sample position Information and project to be detected can also include that sample extraction device identification and detection device identify.
After corresponding sample extraction equipment receives sample extraction instruction, sample bit is moved to based on sample extraction instruction Confidence is ceased corresponding position, is extracted the sample of sample position information corresponding position based on the corresponding sample extraction mode of project to be detected This, obtains sample, and sample is placed into the detection sample putting position that detection device identifies corresponding detection device It sets, and is extracted to main control device feedback samples and complete information.
Sample is placed into after the detection sample placement location of detection device by sample extraction equipment, and detection device exists When detecting that its detection sample placement location placed sample, sample placement information can be returned to main control device.
Main control device completes information and sample after placement information, based on above-mentioned determination receiving above-mentioned sample extraction Detection parameters, to detection device send detection instruction, which includes sample bar code information, can also include above-mentioned inspection Survey parameter.
After detection device receives detection instruction, the sample for being detected sample placement location to it based on detection instruction is carried out Detection obtains pattern detection intermediate result, and returns to the pattern detection intermediate result to main control device.
After main control device receives pattern detection intermediate result, to the pattern detection intermediate result combination pattern detection parameter Information is further analyzed, and really obtains final sample testing result.
In one embodiment, a kind of computer equipment, including memory and processor are provided, is stored in memory Computer program, the processor realize the pattern detection side in any one embodiment as described above when executing computer program Method.
Computer equipment in one embodiment can be terminal, and internal structure chart can be as shown in Figure 6.The computer Equipment includes processor, memory, network interface, display screen and the input unit connected by system bus.Wherein, the calculating The processor of machine equipment is for providing calculating and control ability.The memory of the computer equipment includes that non-volatile memories are situated between Matter, built-in storage.The non-volatile memory medium is stored with operating system and computer program.The built-in storage is non-volatile The operation of operating system and computer program in storage medium provides environment.The network interface of the computer equipment be used for it is outer The terminal in portion passes through network connection communication.To realize a kind of sample testing method when the computer program is executed by processor.It should The display screen of computer equipment can be liquid crystal display or electric ink display screen, and the input unit of the computer equipment can To be the touch layer covered on display screen, it is also possible to the key being arranged on computer equipment shell, trace ball or Trackpad, also It can be external keyboard, Trackpad or mouse etc..
It will be understood by those skilled in the art that structure shown in Fig. 6, only part relevant to application scheme is tied The block diagram of structure does not constitute the restriction for the computer equipment being applied thereon to application scheme, specific computer equipment It may include perhaps combining certain components or with different component layouts than more or fewer components as shown in the figure.
Those of ordinary skill in the art will appreciate that realizing all or part of the process in above-described embodiment method, being can be with Relevant hardware is instructed to complete by computer program, the computer program can be stored in a non-volatile computer In read/write memory medium, the computer program is when being executed, it may include such as the process of the embodiment of above-mentioned each method.Wherein, To any reference of memory, storage, database or other media used in each embodiment provided herein, Including non-volatile and/or volatile memory.Nonvolatile memory may include read-only memory (ROM), programming ROM (PROM), electrically programmable ROM (EPROM), electrically erasable ROM (EEPROM) or flash memory.Volatile memory may include Random access memory (RAM) or external cache.By way of illustration and not limitation, RAM is available in many forms, Such as static state RAM (SRAM), dynamic ram (DRAM), synchronous dram (SDRAM), double data rate sdram (DDRSDRAM), enhancing Type SDRAM (ESDRAM), synchronization link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM (RDRAM), direct memory bus dynamic ram (DRDRAM) and memory bus dynamic ram (RDRAM) etc..
Therefore, in one embodiment, a kind of computer readable storage medium is provided, computer journey is stored thereon with Sequence realizes the sample testing method in any one embodiment as described above when computer program is executed by processor.
Each technical characteristic of above embodiments can be combined arbitrarily, for simplicity of description, not to above-described embodiment In each technical characteristic it is all possible combination be all described, as long as however, the combination of these technical characteristics be not present lance Shield all should be considered as described in this specification.
The several embodiments of the application above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the concept of this application, various modifications and improvements can be made, these belong to the protection of the application Range.Therefore, the scope of protection shall be subject to the appended claims for the application patent.

Claims (10)

1. a kind of sample testing method, which comprises
Detection instruction is sent to the corresponding detection device of project to be detected, the detection instruction is to control the detection device pair Its sample for detecting sample placement location is detected;
Obtain the pattern detection intermediate result that the detection device returns;
The pattern detection intermediate result is analyzed, final sample detection knot corresponding with the project to be detected is obtained Fruit.
2. according to the method described in claim 1, it is characterized by:
Before sending detection instruction to detection device corresponding with the project to be detected, further includes: be based on the item to be detected Mesh determines corresponding detection parameters;
The detection instruction further includes the detection parameters, and the detection instruction is based on the inspection to control the detection device Parameter is surveyed to detect the sample of detection sample placement location.
3. according to the method described in claim 2, it is characterized in that, determining that corresponding detection is joined based on the project to be detected Number, comprising:
Item detection template corresponding with the project to be detected, the item detection template are transferred based on the project to be detected It include: detection device operating parameter, operating status of the detection device operating parameter to control the detection device is described Detection parameters include the detection device operating parameter.
4. according to the method described in claim 1, it is characterized by:
Before sending detection instruction to detection device corresponding with the project to be detected, further includes: receive pattern detection parameter Setting instruction, the pattern detection parameter setting instruction includes pattern detection parameter information;
The pattern detection intermediate result is analyzed, final sample detection knot corresponding with the project to be detected is obtained Fruit, comprising: analyzed, obtained and the sample based on the pattern detection intermediate result and the pattern detection parameter information The corresponding final sample testing result of the project to be detected of bar code information.
5. according to the method described in claim 4, the sample is examined it is characterized in that, the detection device is PCR detection device Surveying intermediate result includes fluorescence number;
It is analyzed, is obtained and the sample bar code based on the pattern detection intermediate result and the pattern detection parameter information The corresponding final sample testing result of the project to be detected of information, include following items in any one:
First item: being based on predetermined matching relationship, and determination is matched with the fluorescence number and the pattern detection parameter information Testing result, and using the testing result as final sample corresponding with the project to be detected of the sample bar code information Testing result, matching relationship of the matching relationship between fluorescence number, pattern detection parameter information and testing result;
Section 2: the fluorescence number and the pattern detection parameter information input testing result that training obtains in advance are matched into mould Type is tied by the way that the testing result Matching Model is determining with the fluorescence number and the matched detection of the pattern detection parameter information Fruit, and tied the testing result as final sample detection corresponding with the project to be detected of the sample bar code information Fruit.
6. the method according to claim 1, wherein the detection instruction further include detection device mark, it is described Detection device mark is corresponding with the sample bar code information.
7. a kind of sample testing apparatus, described device include:
Control module, for sending detection instruction to the corresponding detection device of project to be detected, the detection instruction is to control The sample that the detection device detects sample placement location to it detects;
Intermediate result obtains module, the pattern detection intermediate result returned for obtaining the detection device;
Analysis module obtains corresponding most with the project to be detected for analyzing the pattern detection intermediate result Whole pattern detection result.
8. a kind of pattern detection system, the system comprises main control devices and detection device:
Main control device, for sending detection instruction to the corresponding detection device of project to be detected, the detection instruction to It controls the detection device and detects the sample of sample placement location to it and detect, and obtain the sample that the detection device returns This detection intermediate result analyzes the pattern detection intermediate result, obtains corresponding with the project to be detected final Pattern detection result;
The detection device detects sample placement location to it based on the detection instruction for receiving the detection instruction Sample is detected, and obtains pattern detection intermediate result, and return to the pattern detection intermediate result to the main control device.
9. a kind of computer equipment, including memory and processor, the memory are stored with computer program, feature exists In the step of processor realizes any one of claims 1 to 6 the method when executing the computer program.
10. a kind of computer readable storage medium, is stored thereon with computer program, which is characterized in that the computer program The step of method described in any one of claims 1 to 6 is realized when being executed by processor.
CN201811378176.5A 2018-11-19 2018-11-19 Sample testing method, sample testing apparatus and pattern detection system Pending CN109580964A (en)

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Application publication date: 20190405