CN109580867A - A kind of Development of Thin-Layer Chromatography instrument - Google Patents
A kind of Development of Thin-Layer Chromatography instrument Download PDFInfo
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- CN109580867A CN109580867A CN201811492864.4A CN201811492864A CN109580867A CN 109580867 A CN109580867 A CN 109580867A CN 201811492864 A CN201811492864 A CN 201811492864A CN 109580867 A CN109580867 A CN 109580867A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
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Abstract
The invention discloses a kind of Development of Thin-Layer Chromatography instrument, belong to chemical analysis instrument field.The device includes expanding box and expansion plate, expanding box is divided into the first development chamber for storing solvent and the second development chamber for storing desiccant by a splitter, the first feeder for adding solvent and the second feeder for adding desiccant are provided on the outside of expanding box, first feeder and the second feeder are penetrated through respectively to two development chambers, waterproof ventilated membrane is provided in expanding box, waterproof ventilated membrane is connected on splitter and the inner sidewall of expanding box, is used for the second development chamber of block.The present invention can add solvent and/or desiccant by the first feeder and the second feeder in the case where not opening expanding box cylinder cap, avoid influencing experimental precision；Solvent and desiccant are spaced using waterproof ventilated membrane, will not influence the work of desiccant, while can prevent solvent or desiccant from passing through again, to prevent the two from mixing.
Description
Technical field
The present invention relates to chemical analysis instrument field, in particular to a kind of Development of Thin-Layer Chromatography instrument.
Background technique
Thin-layer chromatography or thin-layer chromatography (thin-layer chromatography), are to be coated on thin-layer developing plate
On support as stationary phase, using suitable solvent as mobile phase, to mixing sample separated, one kind of identification and quantification
Chromatography technology.Thin-layered chromatography is a kind of adsorption thin-layer chromatography partition method, it adsorbs same adsorbent using each ingredient
Ability is different, makes during mobile phase (solvent) flows through stationary phase (adsorbent), and the continuous Adsorption and desorption that generates is attached, again
Absorption, again desorption, to achieve the purpose that the disconnected from each other of each ingredient.Usually the ingredient with different adsorption capacities is chromatographing
Can have specific relative displacement (Rf), calculation in the process are as follows: the mobile distance of Rf=solute/solution it is mobile away from
From.
Because thin layer chromatography is the chromatographic technique of a kind of " open system ", different regions, Various Seasonal cause to test
Environment is different, and environmental condition is very big to the chromatography behavioral implications of thin-layer chromatography separated object matter.The activity of adsorbent depends on
The relative humidity of experimental situation.In the identical situation of other conditions, influence of the relative humidity to chromatography quality is apparent.It is logical
Often think the poor reproducibility of thin-layer chromatography, it is one of chief reason that lamellae, which is in operation under different relative humidity,.In order not to
With between laboratory and the reproducible test result of Various Seasonal, should be expanded under conditions of relative humidity is controllable as far as possible
Preferably.Existing control method is the sulfuric acid that debita spissitudo is added in a side channel of double flute chromatography cylinder, by the lamellae after point sample
Be put into another side channel, it is closed place 15~30 minutes, then plus solvent be unfolded in the slot of not sulfur acid.Its shortcoming exists
In: addition solvent is inconvenient, when solvent is added, it is necessary to open chromatography cylinder cap, can make gas in chromatography cylinder and outer in this way
The gas exchanges on boundary destroy the various stable states in chromatography cylinder；It is easy to splash solvent on lamellae, and is easy to make sulfuric acid
Solution and solvent mixing.
Summary of the invention
The present invention provides a kind of Development of Thin-Layer Chromatography instrument, can solve existing for Development of Thin-Layer Chromatography instrument in the prior art
It is not easy to addition solvent and/or desiccant, is easy the problem of mixing solvent and desiccant.
A kind of Development of Thin-Layer Chromatography instrument, including expanding box and expansion plate, the expanding box are divided by a splitter and are used for
The first development chamber of solvent and the second development chamber for storing desiccant are stored, is provided with and is used on the outside of the expanding box
The first feeder and the second feeder for adding desiccant for adding solvent, first feeder and described second into
Glassware is penetrated through respectively to two development chambers, and waterproof ventilated membrane, the waterproof ventilated membrane connection are provided in the expanding box
On the splitter and the inner sidewall of the expanding box, for the second development chamber described in block.
More preferably, first feeder and second feeder include the charging of funnel and perforation to the funnel
Pipe, the feed pipe are penetrated through far from one end of the funnel to the expanding box, and the feed pipe is integrally u-shaped and is turned under
It is bent.
More preferably, the lowermost end of the feed pipe offers the discharge duct for holding and expanding agent or desiccant outflow, institute
State the valve being provided on discharge duct for controlling its on-off.
It more preferably, further include unloading equipment comprising motor, drive shaft, fixed gear, adjustment gear, fixed rack, tune
Section sliding rail and adjustment axis, the motor are arranged on the lateral wall of the expanding box, and the drive shaft is located in the expanding box,
The motor driven is connected to the drive shaft, and the fixed gear is coaxially fixed in the drive shaft, the driving
External splines is offered on axis, and the internal spline matched with the external splines, the adjustment gear are offered in the adjustment gear
By the internal spline, coaxially slideably driving is arranged in the drive shaft, and the fixed rack is fixed at the exhibition
In unpacking, the both ends of the adjustment axis are fixed in the expanding box, and the adjusting sliding rail is movably disposed at described
It adjusts on sliding rail；
The back side of the expansion plate is provided with the rack gear matched with the fixed gear and the adjustment gear, the exhibition
The two sides for opening plate are respectively slidably arranged in the fixed rack and the adjusting sliding rail, and the drive shaft drives described solid
When fixed gear and the adjustment gear rotate, drive the expansion plate along the fixed rack and the extension side for adjusting sliding rail
To movement；
The back side of the expansion plate is provided with hook, and the hook is made of elastic material, the expansion plate with it is described solid
When fixed gear and the adjustment gear are detached from, the hook can be hung on the side wall of the expanding box.
It more preferably, further include control device comprising first processor and timer, the first processor and the meter
When device signal connect, the motor signal is connected to the first processor.
More preferably, the unloading equipment further includes whether being deployed into predeterminated position for monitoring solvent and capable of controlling institute
State the monitoring module of motor action.
More preferably, the monitoring module include electrode, the conductive plate for connecting the electrode, paper folding, second processor,
First wireless transmitter module and wireless receiving module；
The first wireless transmitter module signal is connected to the second processor, the wireless receiving module signal connection
To the first processor, first wireless transmitter module with the wireless receiving module for communicating；
Pedestal is provided on the expansion plate, the conductive plate is rotatably arranged on the pedestal；
The cross section of the paper folding is triangle, and face where one right-angle side is fitted on the expansion plate, bevel edge institute
It is resisted against on the conductive plate in face, is used to support the conductive plate far from the electrode, becomes when the paper folding absorbs solvent
After soft, the electrode is connected to generate electric signal in the conductive plate.
More preferably, the monitoring module includes sampling sensor, third processor and the second wireless transmitter module, described to adopt
Sample sensor is used to obtain the image information of expansion plate, and the sampling sensor and the equal signal of second wireless transmitter module connect
It is connected to the third processor, second wireless transmitter module with the wireless receiving module for communicating.
More preferably, further include pin shaft and spring, offered in the drive shaft several along the drive shaft extending direction cloth
The adjustment hole set, the side of the adjustment gear are provided with scotch, and locking groove is offered in the scotch, and the pin shaft is worn
The locking groove is crossed to protrude into the adjustment hole, the spring one end is connected in the locking groove, the other end be connected to it is described
On pin shaft, the pin shaft at least has the first working condition and the second working condition, when being in the first working condition, the bullet
Spring compression, the pin shaft are separated with the drive shaft；When being in the second working condition, the spring restores, the pin shaft
It protrudes into the adjustment hole.
It more preferably, further include that the openable and closable outer case of upper cover is provided in the outer case for storing the expanding box
Temperature and humidity control device, the temperature and humidity control device include temperature sensor, humidity sensor, adding thermal resistance, fourth process
Device and dehumidifier, the temperature sensor, the humidity sensor, the adding thermal resistance and the equal signal of the dehumidifier are connected to
The fourth processor.
The present invention provides a kind of Development of Thin-Layer Chromatography instrument, can not open exhibition by the first feeder and the second feeder
Solvent and/or desiccant are added in the case where unpacking cylinder cap, solvent and/or desiccant is avoided to splash expansion plate when adding
On, influence experimental precision；Solvent and desiccant are spaced using waterproof ventilated membrane, waterproof ventilated membrane can be through the air
Hydrone, will not influence the work of desiccant, while can prevent solvent or desiccant from passing through again, to both prevent mixed
It closes.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram one of Development of Thin-Layer Chromatography instrument provided by the invention；
Fig. 2 is a kind of structural schematic diagram two of Development of Thin-Layer Chromatography instrument provided by the invention；
Fig. 3 is the top view of Fig. 1；
Fig. 4 is the left view of Fig. 1；
Fig. 5 is C-C cross-sectional view in Fig. 4；
Fig. 6 is partial enlarged view at D in Fig. 5；
Fig. 7 is A-A cross-sectional view in Fig. 3；
Fig. 8 is partial enlarged view at E in Fig. 7；
Fig. 9 is B-B cross-sectional view in Fig. 3；
Figure 10 is the structural schematic diagram one of expansion plate in Fig. 1；
Figure 11 is the structural schematic diagram two of expansion plate in Fig. 1；
Figure 12 is partial enlarged view at F in Figure 11；
Figure 13 is the structural schematic diagram three of expansion plate in Fig. 1；
Figure 14 is the structural schematic diagram of the first feeder in Fig. 1；
Figure 15 is a kind of systematic schematic diagram one of Development of Thin-Layer Chromatography instrument provided by the invention；
Figure 16 is a kind of systematic schematic diagram two of Development of Thin-Layer Chromatography instrument provided by the invention；
Figure 17 is a kind of systematic schematic diagram three of Development of Thin-Layer Chromatography instrument provided by the invention；
Figure 18 is a kind of systematic schematic diagram four of Development of Thin-Layer Chromatography instrument provided by the invention；
Figure 19 is a kind of structural schematic diagram with outer case of Development of Thin-Layer Chromatography instrument provided by the invention.
Description of symbols:
10, expanding box, the 11, first feeder, 111, funnel, 112, feed pipe, 1121, discharge duct, the 12, second charging
Device, 13, cylinder cap, 14, fixed rack, 15, adjusting sliding rail, 16, adjustment axis, 17, splitter, 20, motor, 21, drive shaft, 22,
Fixed gear, 23, adjustment gear, 231, scotch, 232, pin shaft, 233, spring, 30, expansion plate, 31, rack gear, 32, hook,
40, monitoring module, 41, conductive plate, 42, pedestal, 43, paper folding, 44, electrode, the 45, first wireless transmitter module, 46, second processing
Device, 50, waterproof ventilated membrane, 60, outer case, 61, adding thermal resistance, 62, dehumidifier, 70, sampling sensor.
Specific embodiment
With reference to the accompanying drawing, the specific embodiment of the present invention is described in detail, it is to be understood that of the invention
Protection scope be not limited by the specific implementation.
Embodiment one:
As shown in Figures 1 to 7, a kind of Development of Thin-Layer Chromatography instrument provided in an embodiment of the present invention, including expanding box 10 and exhibition
Open plate 30, expanding box 10 by a splitter 17 is divided into the first development chamber for storing solvent and for storing desiccant
Second development chamber, the tapered structure of splitter 17 are located at 10 middle position of expanding box, as shown in Figure 1 to Figure 4, the outside of expanding box 10
It is provided with the first feeder 11 for adding solvent and the second feeder 12 for adding desiccant, the first feeder 11
It is penetrated through respectively with the second feeder 12 to two development chambers, as shown in fig. 7, being provided with waterproof ventilated membrane 50 in expanding box 10, is prevented
Water ventilated membrane 50 is connected on the inner sidewall of splitter 17 and expanding box 10, is used for the second development chamber of block, waterproof ventilated membrane 50,
The side wall of splitter 17, the bottom plate of expanding box 10 and expanding box 10 surrounds a closed storage space, waterproof ventilated membrane 50 jointly
It is a kind of novel high polymer waterproof material, in the state of steam, particle water is very tiny, according to the principle of capillary moving,
Capillary can smoothly be penetrated into the other side, so that vapour phenomenon occur.After moisture condensation becomes droplet, particle becomes larger,
Due to the effect (mutual " pull and contend with " between hydrone) of droplet surface tension, hydrone cannot smoothly be detached from droplet infiltration
To the other side, that is, the infiltration of water is prevented to occur, steam film is made to have the function of waterproof.Therefore work as and pass through the first feeder
11 and second feeder 12 add solvent and desiccant respectively after, waterproof ventilated membrane 50 can separate the two, simultaneously because
The steam in air in expanding box 10 can penetrate waterproof ventilated membrane 50, therefore will not influence the desiccation of desiccant, from
And it can be used while realizing dry to avoid solvent and desiccant mixed influence.The above-mentioned preferred concentrated sulfuric acid of desiccant,
Also other liquid desiccants substitution can be used.
Specifically, as shown in figure 14, the first feeder 11 and the second feeder 12 include funnel 111 and penetrate through to funnel
111 feed pipe 112, feed pipe 112 are penetrated through far from one end of funnel 111 to expanding box 10, and feed pipe 112 is whole u-shaped
And be bent downwardly, the lower end perforation of funnel 111 is connected to feed pipe 112, and convenient for charging, feed pipe 112 is U-shaped, is turned under
Song, the perforation of feed pipe 112 is located to the port of expanding box 10 and the bottom wall of expanding box 10 is at the same level, in order to after the completion of expansion
Facilitate the discharge of the desiccant and solvent in expanding box 10, U-shaped structure can make to remain certain exhibition in feed pipe 112
Agent or desiccant are opened, so that air and extraneous air inside expanding box 10 be made to be isolated, outside air is avoided to enter cabinet
It is interior, influence the environment in expanding box 10.
Further, the lowermost end of feed pipe 112 offers the discharge duct for holding and expanding agent or desiccant outflow
1121, it is provided with the valve for controlling its on-off on discharge duct 1121, after expansion, opens valve, in expanding box 10
Solvent and desiccant flowed out by discharge duct 1121, clear water is added by 10 upper opening of expanding box and is rinsed, is rinsed
Waste water afterwards can be flowed out by discharge duct 1121, convenient for the cleaning of expanding box 10.
Embodiment two:
Expansion plate 30 in the prior art needs manually to monitor in time to take out expansion plate 30 after expansion,
Otherwise solvent is easy " race " mistake, causes the failure of an experiment, therefore the present embodiment further includes unloading equipment, as shown in Figures 5 to 9,
Unloading equipment includes motor 20, drive shaft 21, fixed gear 22, adjustment gear 23, fixed rack 14, adjusts sliding rail 15 and adjust
Axis 16, motor 20 are arranged on the lateral wall of expanding box 10, and drive shaft 21 is located in expanding box 10, and the output shaft of motor 20 passes through
The side wall of expanding box 10 is drivingly connected to drive shaft 21, and fixed gear 22 is coaxially fixed in drive shaft 21, drive shaft 21
On offer external splines, the internal spline matched with external splines is offered in adjustment gear 23, adjustment gear 23 passes through internal spline
Coaxially slideably driving is arranged in drive shaft 21, and spline fitted can guarantee that adjustment gear 23 can prolonging along drive shaft 21
Direction sliding is stretched, while can guarantee rotate when drive shaft 21 rotates with synchronous drive adjustment gear 23 again, as shown in figure 5,
Fixed rack 14 is fixed in expanding box 10, is preferably disposed in the one side wall of expanding box 10, and the both ends of adjustment axis 16 are solid
It is fixed to be arranged in expanding box 10, it adjusts sliding rail 15 and is movably disposed on adjusting sliding rail 15, adjustment axis 16 is two, along fixation
The extending direction of sliding rail 14 is arranged, and adjusts and offers adjustment hole on sliding rail 15, and adjustment axis 16 passes through adjustment hole, adjusts 15 He of sliding rail
Fixed rack 14 is arranged in parallel, and the two cooperates to expansion plate 30 can be in the effect for adjusting sliding rail 15 and fixed rack 14
It is lower to be moved along fixation locus；It is adjustable solid by adjusting sliding rail 15 since expansion plate 30 has plurality of specifications of different sizes
The distance between determine sliding rail 14 and adjust sliding rail 15, to be applicable in the expansion plate 30 of a variety of different sizes；
As shown in figure 13, the back side of expansion plate 30 is provided with the rack gear matched with fixed gear 22 and adjustment gear 23
31, it adjusts and offers sliding slot on sliding rail 15 and fixed rack 14, fixation is respectively slidably arranged in the two sides of expansion plate 30
It sliding rail 14 and adjusts in the sliding slot of sliding rail 15, as shown in figures 7 and 9, fixed rack 14 and adjusts sliding rail 15 along from expanding box
10 openings are tilted towards the directions of the first development chambers, and making expansion plate 30 in fixed rack 14 and adjust can be under the limit of sliding rail 15
It is protruded into expanding box 10 with an inclined angle, expansion plate 30 can protrude into the first expansion along fixed rack 14 and adjusting sliding rail 15
Room drives expansion plate 30 to slide along fixed rack 14 and adjusting when the fixed gear 22 of the drive of drive shaft 21 and adjustment gear 23 rotate
The extending direction of rail 15 is mobile, and before expansion, after importing solvent, the atmosphere of box house is unstable, and solvent is still not
Saturation, carrying out other atmosphere in expansion air at this time will affect the precision of expansion, therefore usually require first to fall before the experiments
Enter solvent, waiting for a period of time is saturated the atmosphere of the solvent of box house, case lid is then opened, by 30 side of expansion plate
Formula, but the atmosphere that this mode will lead to box house when opening case lid changes, atmosphere is again in the case being saturated originally
It is possible that is become is unsaturated to have an impact to experimental precision, and pass through fixed rack 14, adjusting sliding rail 15 and fixed tooth
The mating reaction of wheel 22, adjustment gear 23 and rack gear 31 can be made in the engagement of fixed gear 22, adjustment gear 23 and rack gear 31
Under, first expansion plate 30 is limited, is located in the box body expansion plate 30, but do not contact with solvent, box house carried out pre-
Saturation rotates after reaching saturation state in expanding box 10, then through control motor 20, and fixed gear 22 and adjustment gear 23 exist
It is rotated under the drive of drive shaft 21 and then drives expansion plate 30 mobile, so that expansion plate 30 be made to protrude into solvent, be unfolded
Operation, whole process can guarantee the stability of 10 internal atmosphere of expanding box without opening case lid, improve experimental precision；
The back side of expansion plate 30 is provided with hook 32, and hook 32 is made of elastic material, expansion plate 30 and fixed gear 22
And when the disengaging of adjustment gear 23, hook 32 can be hung on the side wall of expanding box 10.As shown in figure 9, drive shaft 21 is located at exhibition
Inside unpacking 10, fixed gear 22 and adjustment gear 23 are located at close to the position of 10 top edge of expanding box, after the completion of expansion, electricity
Machine 20 rotates, and drive shaft 21 is driven to rotate, and drive shaft 21 transfers fixed gear 22 and adjustment gear 23 rotates, thus in expansion plate
Drive expansion plate 30 to moving obliquely under the action of the rack gear 31 at 30 backs, when expansion plate 30 moves to front end and fixed rack
14 and when adjusting sliding rail 15 and being detached from, 32 inner sidewalls for contradicting expanding box 10 are linked up at this time, and expansion plate 30 is due to losing fixation
Sliding rail 14 and the support for adjusting sliding rail 15 can generate overturning under the effect of gravity, therefore expansion plate 30 can be in gravity and hook 32
Downward overturning is generated under the action of the conflict power of the inner sidewall of suffered expanding box 10, the center of expansion plate 30 is being opened up at this time
Unpacking 10 outside, since hook 32 is contradicted with the inner sidewall of expanding box 10 at this time, expansion plate 30 is linked up with when overturning
32 active force by expanding box 10 makes expansion plate 30 without departing from expanding box 10, after the overturning to a certain degree of expansion plate 30, finally
It forms hook 32 to hang on the side wall of expanding box 10, expansion plate 30 is located at 10 outside of expanding box, while being hung in expanding box 10.
There is cylinder cap 13, linking up with 32 in order to prevent makes to be formed between cylinder cap 13 and expanding box 10 at the upper opening of expanding box 10
Gap escapes solvent, influences the health of experimenter.Therefore the medial surface of cylinder cap 13 is provided with layer of silica gel, 13 He of cylinder cap
Hinged using torsional spring between expanding box 10, torsional spring allows cylinder cap 13 to be adjacent to 10 upper end of expanding box always in its natural state
Face, when hook 32 is between cylinder cap 13 and expanding box 10, since the active force of torsional spring makes cylinder cap 13 push down hook 32, and silicon
Glue-line deformation, makes the sealed around of hook 32, when so that hook 32 is between cylinder cap 13 and expanding box 10, can still guarantee
The sealing of expanding box 10.
It is of course also possible to use the first magnet is arranged in the upper end of expanding box 10, it is arranged between layer of silica gel and cylinder cap 13
Second magnet enables cylinder cap 13 to be closely adjacent in 10 upper surface of expanding box by the suction of magnet.
Embodiment three:
On the basis of example 2, in order to easily control saturation time, realization is facilitated to make saturation automatically after the completion
Expansion plate 30 protrudes into solvent, and as shown in figure 15, the present embodiment further includes control device comprising first processor and timing
Device, first processor are connect with timer-signals, and 20 signal of motor is connected to first processor.First processor and timer peace
On the lateral wall of expanding box 10.Saturation time is set by timer, when countdown terminates, timer is to first processor
Signal is sent, first processor receives signal and controls motor 20 and rotates, and drives drive shaft 21 and then by fixed gear 22, tune
Section gear 23 and rack gear 31 drive expansion plate 30 to protrude into solvent, and built-in length can pass through the turning collar of control motor 20
Prompt point can be arranged to control in number on 10 inner sidewall of expanding box, when initial, expansion plate 30 is inserted into fixed rack 14 and is adjusted
It saves between sliding rail 15, and pushes expansion plate 30 to prompt point, then since the diameter of fixed gear 22 and adjustment gear 23 is fixed,
Its distance for driving expansion plate 30 mobile that rotates a circle is certain, and motor 20 rotates a circle and drives fixed gear 22 and adjust
Gear 23 rotates a circle, and stepper motor 20 can be used in motor 20, convenient for control stroke, controls 20 turning collar of motor by processor
The i.e. controllable expansion plate 30 of number protrudes into distance.Timer can certainly be omitted, it will be at code write-in by way of programming
Reason device can also realize above-mentioned function course.
Example IV:
On the basis of embodiment two or three, for the ease of expansion plate 30 be unfolded after can be automatically by expansion plate 30
It lays down, avoids excessively being unfolded, unloading equipment further includes whether being deployed into predeterminated position for monitoring solvent and capable of controlling electricity
The monitoring module 40 that machine 20 acts.
Specifically, as shown in Figure 10, Figure 11, Figure 12 and Figure 16, monitoring module 40 includes electrode 44, for connecting electrode 44
Conductive plate 41, paper folding 43, second processor 46, the first wireless transmitter module 45 and wireless receiving module；
First wireless transmitter module, 45 signal is connected to second processor 46, and wireless receiving module signal is connected at first
Device is managed, the first wireless transmitter module 45 with wireless receiving module for communicating；
Pedestal 42 is provided on expansion plate 30, conductive plate 41 is rotatably arranged on pedestal 42；
The cross section of paper folding 43 is triangle, and face where one right-angle side is fitted on expansion plate 30, face where bevel edge
It is resisted against on conductive plate 41, is used to support conductive plate 41 far from electrode 44, after paper folding 43, which absorbs solvent, to soften, conductive plate 41
Conduction electrode 44 is to generate electric signal.When solvent is expanded to predeterminated position, paper folding 43 absorbs rapidly solvent, and paper folding 43 is inhaled
Quality softens after receiving solvent, to be difficult to support conductive plate 41, conductive plate 41 pushes paper folding 43 under the effect of gravity to paste
Tight electrode 44, electrode 44 are switched on, and second processor 46 receives signal, and is sent signal by the first wireless transmitter module 45
To wireless receiving module, wireless receiving module sends the signal to first processor, and first processor controls motor 20 and reversely turns
It is dynamic, it drives drive shaft 21 to rotate and then drives expansion plate 30 to be displaced outwardly by fixed gear 22 and adjustment gear 23, expansion plate
30 upper ends contradict cylinder cap 13, cylinder cap 13 are opened a part, expansion plate 30 continues to be displaced outwardly, the same embodiment of subsequent action process
Two action process, final expansion plate 30 are hung on the outside of expanding box 10.
The present embodiment additionally provides another alternative scheme, and as shown in figure 17, monitoring module 40 includes sampling sensing
Device 70, third processor and the second wireless transmitter module, sampling sensor 70 are used to obtain the image information of expansion plate 30, sampling
Sensor 70 and the equal signal of the second wireless transmitter module are connected to third processor, and the second wireless transmitter module is used for and wirelessly connects
Receive module communication.After being unfolded on expansion plate 30 due to solvent, the color of the part of the expansion plate 30 of solvent has been adsorbed
There is a biggish color difference with the color of the part of the expansion plate 30 still without adsorbing solvent, when 70 original state of sampling sensor is
Towards the predeterminated position of expansion plate 30, color-values are to implement to obtain image information being simultaneously sent at third with fixed value
Device is managed, when solvent is expanded to predeterminated position, 30 color difference of expansion plate generates variation, and third processor detects signal, passes through
Second wireless transmitter module sends the signal to wireless receiving module, and wireless receiving module sends the signal to first processor,
First processor controls motor 20 and rotates, and subsequent action is the same as embodiment two.
It wherein, is the prior art above by the technical solution that chromatic aberration generates signal.Such as application number
201310308465.9 technical solution, for another example application No. is 02133311.4 technical solution or application No. is
200510002800.8 algorithm.The technical solution of above-mentioned application number can also be directlyed adopt to realize the identification of color difference, so as to right
Whether expansion is monitored in place.
Embodiment five:
In order to enable adjustment gear 23 to be stably positioned in adjusting position, avoid placing by expanding box 10 do not measure up from
And it is caused to move along drive shaft 21, on the basis of example 2, as shown in figure 8, the present embodiment further includes pin shaft 232 and bullet
Spring 233 offers several adjustment holes along 21 extending direction of drive shaft arrangement, the side setting of adjustment gear 23 in drive shaft 21
There is scotch 231, locking groove is offered in scotch 231, pin shaft 232 passes through locking groove and protrudes into adjustment hole, 233 one end of spring
Be connected in locking groove, the other end is connected on pin shaft 232, when needing mobile adjustment gear 23, pin shaft 232 is pulled up
It is dynamic, so that pin shaft 232 and adjustment hole is separated, i.e., the position of adjustable adjustment gear 23, and when needing adjustment gear 23 fixed,
Pin shaft 232 only need to be unclamped, pin shaft 232 protrudes into adjustment hole under the active force of spring 233.The position of adjustment hole and different size
The width of expansion plate 30 is adapted.
Embodiment six:
On the basis of embodiment one to five, as shown in Figure 18 and Figure 19, the present embodiment further includes that upper cover is openable and closable outer
Cabinet 60 is provided with temperature and humidity control device, temperature and humidity control device includes temperature for storing expanding box 10 in outer case 60
Sensor, humidity sensor, adding thermal resistance 61, fourth processor and dehumidifier 62, temperature sensor, humidity sensor, heating
Resistance 61 and the equal signal of dehumidifier 62 are connected to fourth processor.Temperature sensor detects between outer case 60 and expanding box 10
The temperature of environment, and adding thermal resistance 61 is controlled by fourth processor and is heated, to adjust local ambient temperature, utilize humidity
Sensor detects the humidity of local environment, controls dehumidifier 62 by fourth processor, adjusts the humidity of local environment.Wherein remove
Wet device 62 is the prior art, can be blower or such as application No. is 201410645079.3 dehumidifiers 62.
Disclosed above is only several specific embodiments of the invention, and still, the embodiment of the present invention is not limited to this, is appointed
What what those skilled in the art can think variation should all fall into protection scope of the present invention.
Claims (10)
1. a kind of Development of Thin-Layer Chromatography instrument, including expanding box and expansion plate, the expanding box are divided by a splitter for depositing
Put the first development chamber of solvent and the second development chamber for storing desiccant, which is characterized in that the outside of the expanding box
Be provided with the first feeder for adding solvent and the second feeder for adding desiccant, first feeder and
Second feeder is penetrated through respectively to two development chambers, is provided with waterproof ventilated membrane, the waterproof in the expanding box
Ventilated membrane is connected on the splitter and the inner sidewall of the expanding box, for the second development chamber described in block.
2. a kind of Development of Thin-Layer Chromatography instrument as described in claim 1, which is characterized in that first feeder and described second
Feeder includes the feed pipe of funnel and perforation to the funnel, and the feed pipe is penetrated through far from one end of the funnel to institute
Expanding box is stated, the feed pipe is integrally u-shaped and is bent downwardly.
3. a kind of Development of Thin-Layer Chromatography instrument as claimed in claim 2, which is characterized in that the lowermost end of the feed pipe offers
For the discharge duct that holding and expanding agent or desiccant are flowed out, the valve for controlling its on-off is provided on the discharge duct.
4. a kind of Development of Thin-Layer Chromatography instrument as described in claim 1, which is characterized in that further include unloading equipment comprising electricity
Machine, fixed gear, adjustment gear, fixed rack, adjusts sliding rail and adjustment axis at drive shaft, and the motor is arranged in the expansion
On the lateral wall of case, the drive shaft is located in the expanding box, and the motor driven is connected to the drive shaft, the fixation
Gear is coaxially fixed in the drive shaft, and external splines is offered in the drive shaft, is offered in the adjustment gear
The internal spline matched with the external splines, by the internal spline, coaxially slideably driving is arranged in institute the adjustment gear
It states in drive shaft, the fixed rack is fixed in the expanding box, and the both ends of the adjustment axis are fixed at described
In expanding box, the adjusting sliding rail is movably disposed on the adjusting sliding rail；
The back side of the expansion plate is provided with the rack gear matched with the fixed gear and the adjustment gear, the expansion plate
Two sides be respectively slidably arranged in the fixed rack and the adjusting sliding rail, the drive shaft drives the fixed tooth
When wheel and adjustment gear rotation, the expansion plate is driven to move along the fixed rack and the extending direction for adjusting sliding rail
It is dynamic；
The back side of the expansion plate is provided with hook, and the hook is made of elastic material, the expansion plate and the fixed tooth
When wheel and the adjustment gear are detached from, the hook can be hung on the side wall of the expanding box.
5. a kind of Development of Thin-Layer Chromatography instrument as claimed in claim 4, which is characterized in that further include control device comprising the
One processor and timer, the first processor are connect with the timer-signals, and the motor signal is connected to described
One processor.
6. a kind of Development of Thin-Layer Chromatography instrument as claimed in claim 5, which is characterized in that the unloading equipment further includes for supervising
Survey whether solvent is deployed into predeterminated position and can control the monitoring module of the motor action.
7. a kind of Development of Thin-Layer Chromatography instrument as claimed in claim 6, which is characterized in that the monitoring module includes electrode, uses
In conductive plate, paper folding, second processor, the first wireless transmitter module and the wireless receiving module of connecting the electrode；
The first wireless transmitter module signal is connected to the second processor, and the wireless receiving module signal is connected to institute
First processor is stated, first wireless transmitter module with the wireless receiving module for communicating；
Pedestal is provided on the expansion plate, the conductive plate is rotatably arranged on the pedestal；
The cross section of the paper folding is triangle, and face where one right-angle side is fitted on the expansion plate, face where bevel edge
It is resisted against on the conductive plate, is used to support the conductive plate far from the electrode, after the paper folding, which absorbs solvent, to soften,
The electrode is connected to generate electric signal in the conductive plate.
8. a kind of Development of Thin-Layer Chromatography instrument as claimed in claim 6, which is characterized in that the monitoring module includes sampling sensing
Device, third processor and the second wireless transmitter module, the sampling sensor is used to obtain the image information of expansion plate, described to adopt
Sample sensor and the equal signal of the second wireless transmitter module are connected to the third processor, second wireless transmitter module
For being communicated with the wireless receiving module.
9. a kind of Development of Thin-Layer Chromatography instrument as claimed in claim 4, which is characterized in that further include pin shaft and spring, the drive
Several adjustment holes along drive shaft extending direction arrangement are offered on moving axis, the side of the adjustment gear is provided with stop
Block offers locking groove in the scotch, and the pin shaft passes through the locking groove and protrudes into the adjustment hole, the spring one
End is connected in the locking groove, the other end is connected on the pin shaft, and the pin shaft at least has the first working condition and the
Two working conditions, when being in the first working condition, the spring-compressed, the pin shaft is separated with the drive shaft；Work as place
When the second working condition, the spring restores, and the pin shaft protrudes into the adjustment hole.
10. a kind of Development of Thin-Layer Chromatography instrument as described in any one of claims 1-9, which is characterized in that further include that upper cover can
The outer case of folding is provided with temperature and humidity control device, the temperature and humidity control for storing the expanding box in the outer case
Device processed includes temperature sensor, humidity sensor, adding thermal resistance, fourth processor and dehumidifier, the temperature sensor, institute
It states humidity sensor, the adding thermal resistance and the equal signal of the dehumidifier and is connected to the fourth processor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811492864.4A CN109580867B (en) | 2018-12-07 | 2018-12-07 | Thin-layer chromatography expandes appearance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811492864.4A CN109580867B (en) | 2018-12-07 | 2018-12-07 | Thin-layer chromatography expandes appearance |
Publications (2)
| Publication Number | Publication Date |
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| CN109580867A true CN109580867A (en) | 2019-04-05 |
| CN109580867B CN109580867B (en) | 2020-09-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201811492864.4A Expired - Fee Related CN109580867B (en) | 2018-12-07 | 2018-12-07 | Thin-layer chromatography expandes appearance |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110470784A (en) * | 2019-06-13 | 2019-11-19 | 广州科曼生物科技有限公司 | A kind of thin-layer chromatography self-presenting devices and Automatic-expanding method |
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| CN107843684A (en) * | 2017-12-28 | 2018-03-27 | 王洪娥 | A kind of thin layer chromatograph developing cylinder |
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|---|---|---|---|---|
| GB1046282A (en) * | 1963-01-11 | 1966-10-19 | Euratom | Method and apparatus for thin-layer chromatography |
| US3535086A (en) * | 1967-10-31 | 1970-10-20 | Eastman Kodak Co | Portable unit for thin-layer chromatographic analysis |
| CN203455324U (en) * | 2013-09-30 | 2014-02-26 | 齐齐哈尔医学院 | Sealed saturated chromatography cylinder |
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| CN205426872U (en) * | 2016-03-31 | 2016-08-03 | 刘凤艳 | Thin -layer chromatography of suspension formula expandes case |
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| CN109580867B (en) | 2020-09-01 |
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